Aliases & Classifications for Annular Erythema

MalaCards integrated aliases for Annular Erythema:

Name: Annular Erythema 57 55 73

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant


HPO:

32
annular erythema:
Inheritance autosomal dominant inheritance


Summaries for Annular Erythema

MalaCards based summary : Annular Erythema is related to keratolytic winter erythema and lupus erythematosus. An important gene associated with Annular Erythema is HSPG2 (Heparan Sulfate Proteoglycan 2), and among its related pathways/superpathways are Integrin Pathway and Immune response Role of DAP12 receptors in NK cells. Affiliated tissues include t cells, skin and colon, and related phenotypes are erythema and integument

Description from OMIM: 106500

Related Diseases for Annular Erythema

Graphical network of the top 20 diseases related to Annular Erythema:



Diseases related to Annular Erythema

Symptoms & Phenotypes for Annular Erythema

Symptoms via clinical synopsis from OMIM:

57
Skin:
annular erythema


Clinical features from OMIM:

106500

Human phenotypes related to Annular Erythema:

32
# Description HPO Frequency HPO Source Accession
1 erythema 32 HP:0010783

MGI Mouse Phenotypes related to Annular Erythema:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.13 HSPG2 ICAM1 ITGB2
2 vision/eye MP:0005391 8.8 HSPG2 ICAM1 ITGB2

Drugs & Therapeutics for Annular Erythema

Search Clinical Trials , NIH Clinical Center for Annular Erythema

Genetic Tests for Annular Erythema

Anatomical Context for Annular Erythema

MalaCards organs/tissues related to Annular Erythema:

41
T Cells, Skin, Colon, Breast, Prostate, Thyroid, Neutrophil

Publications for Annular Erythema

Articles related to Annular Erythema:

(show top 50) (show all 110)
# Title Authors Year
1
Two cases of annular erythema without bullous lesions by autoimmune blistering diseases. ( 26382039 )
2018
2
Annular erythema nodosum leprosum reaction in a young male: a rare presentation. ( 29392708 )
2018
3
Exertional myalgia, contractures and annular erythema in a patient with muscle lactate dehydrogenase (LDH) deficiency. ( 29198466 )
2018
4
A case of eosinophilic annular erythema as a presenting sign for autoimmune hepatitis. ( 29387758 )
2018
5
Atypical presentation of eosinophilic annular erythema in a 5-year-old girl. ( 29341284 )
2018
6
Efficacy of suplatast tosilate in a case of recurrent eosinophilic annular erythema. ( 29655235 )
2018
7
Eosinophilic annular erythema treated with dupilumab. ( 29790187 )
2018
8
Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report. ( 30186440 )
2018
9
Image Gallery: Annular erythema related to Capnocytophaga canimorsus bacteraemia after a dog bite. ( 30387520 )
2018
10
Eosinophilic annular erythema: A late but complete response to hydroxychloroquine. ( 26768795 )
2017
11
Eosinophilic Annular Erythema Associated with Churg-Strauss Syndrome. ( 29200781 )
2017
12
Bullous eosinophilic annular erythema. ( 27511273 )
2017
13
Eosinophilic annular erythema in adults: report of two cases and review of the literature. ( 29267450 )
2017
14
Eosinophilic annular erythema localized on the neck. ( 29165308 )
2017
15
Dapsone for Recalcitrant Eosinophilic Annular Erythema: A Case Report and Literature Review. ( 29222624 )
2017
16
Lymphocytic hidradenitis: A distinctive histopathological finding of annular erythema of SjAPgren syndrome. ( 28771678 )
2017
17
Eosinophilic annular erythema is clinically characterized by central pigmentation reflecting basal melanosis: a clinicopathological study of 10 cases. ( 28543605 )
2017
18
Eosinophilic Annular Erythema Localized to the Palms and the Soles. ( 27904280 )
2016
19
Eosinophilic annular erythema in a patient with autoimmune pancreatitis: Nicotinamide therapy may be beneficial for achieving remission. ( 27129768 )
2016
20
Anti-signal recognition particle antibody-positive polymyositis in a patient with SjAPgren's syndrome showing various types of annular erythema: Positive correlation between the activities of annular erythema and myositis. ( 26972113 )
2016
21
Eosinophilic annular erythema in childhood - Case report. ( 27579748 )
2016
22
Pyoderma gangrenosum and annular erythema associated with SjAPgren's syndrome controlled with minocycline. ( 25899670 )
2015
23
Eosinophilic annular erythema limited on the palms and the soles and possibly associated with thymoma. ( 25816730 )
2015
24
Eosinophilic annular erythema: successful response to ultraviolet B therapy. ( 25958878 )
2015
25
Eosinophilic annular erythema in a patient with metastatic prostate adenocarcinoma. ( 25515818 )
2015
26
Eosinophilic annular erythema: complete clinical response with dapsone. ( 25556880 )
2015
27
Annular erythema in primary Sjogren's syndrome: description of 43 non-Asian cases. ( 24326481 )
2014
28
Eosinophilic annular erythema: attention must be paid. ( 25823085 )
2014
29
Annular erythema of Sjögren's syndrome treated successfully with low-dose cyclosporine. ( 24801928 )
2014
30
Immunohistochemical Analysis of Interleukin-17 Producing T Helper Cells and Regulatory T Cells Infiltration in Annular Erythema Associated with Sjögren's Syndrome. ( 24882975 )
2014
31
Eosinophilic annular erythema is a peculiar subtype in the spectrum of Wells syndrome: a multicentre long-term follow-up study. ( 22731886 )
2013
32
Annular Erythema Associated with SjAPgren's Syndrome Preceding Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with Anti-PL-12 Autoantibodies. ( 24322624 )
2013
33
Annular Erythema and Papules in Infantile Atopic Dermatitis. ( 24202180 )
2013
34
Bullous annular erythema as a cutaneous sign of vaginal stump adenocarcinoma. ( 23463841 )
2013
35
Annular erythema and photosensitivity as manifestations of efavirenz-induced cutaneous reactions: a review of five consecutive cases. ( 23852540 )
2013
36
A new type of annular erythema with perieccrine inflammation: erythema papulatum centrifugum. ( 23948702 )
2013
37
Systemic allergic contact dermatitis to palladium inlay manifesting as annular erythema. ( 22759481 )
2012
38
Eosinophilic annular erythema. ( 22483519 )
2012
39
Spontaneously resolving eosinophilic annular erythema. ( 22794821 )
2012
40
Eosinophilic annular erythema: an expression of the clinical and pathological polymorphism of Wells syndrome. ( 21920240 )
2011
41
Familial annular erythema--a rare dermatology diagnosis. ( 21276056 )
2011
42
Recurrent annular erythema after thymectomy. ( 21527370 )
2011
43
Annular erythema associated with Sjögren's syndrome: review of the literature on the management and clinical analysis of skin lesions. ( 20054701 )
2010
44
Annular erythema as a sign of recurrent breast cancer. ( 20546222 )
2010
45
Is annular erythema developing in a pregnant patient with Sjögren's syndrome a predictor of potential neonatal lupus erythematosus in the infant? ( 21039792 )
2010
46
Mycosis fungoides mimicking an annular erythema. ( 19486059 )
2009
47
Eosinophilic annular erythema responsive to chloroquin. ( 19171544 )
2009
48
Annular erythema associated with anti-Ro/SS-A and anti-La/SS-B antibodies: a new case in a Hispanic patient. ( 19999246 )
2009
49
Eosinophilic annular erythema: a subset of Wells' syndrome or a distinct entity? ( 18638225 )
2008
50
Annular erythema of Sjögren's syndrome. ( 16698414 )
2006

Variations for Annular Erythema

Expression for Annular Erythema

Search GEO for disease gene expression data for Annular Erythema.

Pathways for Annular Erythema

Pathways related to Annular Erythema according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.86 HSPG2 ICAM1 ITGB2
2
Show member pathways
12.05 ICAM1 ITGB2
3 11.97 ICAM1 ITGB2
4
Show member pathways
11.9 ICAM1 ITGB2
5
Show member pathways
11.79 HSPG2 ICAM1 ITGB2
6 11.69 ICAM1 ITGB2
7
Show member pathways
11.68 HSPG2 ITGB2
8 11.64 ICAM1 ITGB2
9
Show member pathways
11.6 HSPG2 ITGB2
10
Show member pathways
11.6 HSPG2 ICAM1 ITGB2
11 11.57 ICAM1 ITGB2
12 11.51 ICAM1 ITGB2
13 11.39 ICAM1 ITGB2
14 11.15 ICAM1 ITGB2
15 11.06 ICAM1 ITGB2
16
Show member pathways
10.98 HSPG2 ICAM1 ITGB2
17 10.94 ICAM1 ITGB2
18 10.8 ICAM1 ITGB2

GO Terms for Annular Erythema

Cellular components related to Annular Erythema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.5 HSPG2 ICAM1 ITGB2
2 external side of plasma membrane GO:0009897 9.26 ICAM1 ITGB2
3 collagen-containing extracellular matrix GO:0062023 9.16 HSPG2 ICAM1
4 membrane raft GO:0045121 8.96 ICAM1 ITGB2
5 focal adhesion GO:0005925 8.8 HSPG2 ICAM1 ITGB2

Biological processes related to Annular Erythema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.48 ICAM1 ITGB2
2 regulation of immune response GO:0050776 9.46 ICAM1 ITGB2
3 leukocyte migration GO:0050900 9.43 ICAM1 ITGB2
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.4 ICAM1 ITGB2
5 regulation of cell shape GO:0008360 9.37 ICAM1 ITGB2
6 cell-cell adhesion GO:0098609 9.32 ICAM1 ITGB2
7 positive regulation of nitric oxide biosynthetic process GO:0045429 9.26 ICAM1 ITGB2
8 leukocyte cell-cell adhesion GO:0007159 9.16 ICAM1 ITGB2
9 cell adhesion mediated by integrin GO:0033627 8.96 ICAM1 ITGB2
10 extracellular matrix organization GO:0030198 8.8 HSPG2 ICAM1 ITGB2

Molecular functions related to Annular Erythema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-containing complex binding GO:0044877 9.16 ICAM1 ITGB2
2 signaling receptor activity GO:0038023 8.96 ICAM1 ITGB2
3 integrin binding GO:0005178 8.62 ICAM1 ITGB2

Sources for Annular Erythema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....