MCID: ANM031
MIFTS: 28

Anomalous Left Coronary Artery from the Pulmonary Artery

Categories: Cardiovascular diseases

Aliases & Classifications for Anomalous Left Coronary Artery from the Pulmonary Artery

MalaCards integrated aliases for Anomalous Left Coronary Artery from the Pulmonary Artery:

Name: Anomalous Left Coronary Artery from the Pulmonary Artery 12 15
Bland White Garland Syndrome 45 74
Bland-White-Garland Syndrome 12
White-Garland Syndrome 12
Alcapa 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060562
MeSH 45 D063748
UMLS 74 C1735886

Summaries for Anomalous Left Coronary Artery from the Pulmonary Artery

Disease Ontology : 12 A coronary artery anomaly in which the left coronary artery (LCA) branches off the pulmonary artery instead of the aortic sinus.

MalaCards based summary : Anomalous Left Coronary Artery from the Pulmonary Artery, also known as bland white garland syndrome, is related to coronary artery anomaly and myocardial infarction. An important gene associated with Anomalous Left Coronary Artery from the Pulmonary Artery is GJA1 (Gap Junction Protein Alpha 1). Affiliated tissues include heart, and related phenotypes are cellular and hematopoietic system

Related Diseases for Anomalous Left Coronary Artery from the Pulmonary Artery

Diseases related to Anomalous Left Coronary Artery from the Pulmonary Artery via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 coronary artery anomaly 29.3 GJA1 PF4 SMUG1 TET1
2 myocardial infarction 10.5
3 mitral valve insufficiency 10.4
4 arteries, anomalies of 10.3
5 orthostatic intolerance 10.3
6 leber congenital amaurosis 10.3
7 ventricular septal defect 10.3
8 coronary aneurysm 10.3
9 congestive heart failure 10.3
10 rere-related disorders 10.3
11 atrial standstill 1 10.1
12 cardiac conduction defect 10.1
13 tetralogy of fallot 10.1
14 endocardial fibroelastosis 10.1
15 patent ductus arteriosus 1 10.1
16 peripartum cardiomyopathy 10.1
17 dilated cardiomyopathy 10.1
18 infective endocarditis 10.1
19 endocarditis 10.1
20 ischemia 10.1
21 myocarditis 10.1
22 aortopulmonary window 10.1
23 coronary artery aneurysm 10.1
24 pulmonary venous return anomaly 10.1
25 ventricular fibrillation, paroxysmal familial, 1 10.1
26 refractory anemia 10.1
27 endocardium disease 10.0 SMUG1 TAZ
28 atrial heart septal defect 10.0
29 distal trisomy 9q 10.0
30 spleen angiosarcoma 9.9 SMUG1 VWF
31 platelet aggregation, spontaneous 9.9 PF4 VWF
32 lymphangiosarcoma 9.9 SMUG1 VWF
33 blood coagulation disease 9.9 PF4 VWF
34 thrombophilia due to activated protein c resistance 9.8 PF4 VWF
35 blood platelet disease 9.8 PF4 VWF
36 megakaryocytic leukemia 9.7 PF4 VWF
37 atrial fibrillation 9.7 GJA1 PF4 VWF
38 hemorrhagic disease 9.6 PF4 VWF
39 heart disease 9.5 GJA1 PF4 TAZ VWF

Graphical network of the top 20 diseases related to Anomalous Left Coronary Artery from the Pulmonary Artery:



Diseases related to Anomalous Left Coronary Artery from the Pulmonary Artery

Symptoms & Phenotypes for Anomalous Left Coronary Artery from the Pulmonary Artery

MGI Mouse Phenotypes related to Anomalous Left Coronary Artery from the Pulmonary Artery:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.7 EHD1 GJA1 PDIA3 SMUG1 TAZ TET1
2 hematopoietic system MP:0005397 9.43 EHD1 GJA1 PDIA3 PF4 TET1 VWF
3 homeostasis/metabolism MP:0005376 9.17 EHD1 GJA1 PF4 PTPRN2 SMUG1 TET1

Drugs & Therapeutics for Anomalous Left Coronary Artery from the Pulmonary Artery

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Resynchronization of Left Ventricular Contraction After Reimplantation of Anomalous Left Coronary Artery Terminated NCT00268112

Search NIH Clinical Center for Anomalous Left Coronary Artery from the Pulmonary Artery

Cochrane evidence based reviews: bland white garland syndrome

Genetic Tests for Anomalous Left Coronary Artery from the Pulmonary Artery

Anatomical Context for Anomalous Left Coronary Artery from the Pulmonary Artery

MalaCards organs/tissues related to Anomalous Left Coronary Artery from the Pulmonary Artery:

42
Heart

Publications for Anomalous Left Coronary Artery from the Pulmonary Artery

Articles related to Anomalous Left Coronary Artery from the Pulmonary Artery:

(show top 50) (show all 194)
# Title Authors Year
1
Anomalous Left Coronary Artery From the Pulmonary Artery Presenting as Dilated Cardiomyopathy With Regional Wall Motion Abnormality on Point-of-Care Ultrasound. ( 30702648 )
2019
2
The detection of retrograde flow from the left anterior descending artery into the main pulmonary artery by 4D-flow cardiac magnetic resonance in a patient with Bland-White-Garland syndrome. ( 30629145 )
2019
3
The outcome of mitral regurgitation after the repair of anomalous left coronary artery from the pulmonary artery in infants and older children. ( 29528421 )
2018
4
Anomalous Left Coronary Artery From the Pulmonary Artery: Masquerading as Peripartum Cardiomyopathy. ( 29530774 )
2018
5
Anomalous left coronary artery from the pulmonary artery (ALCAPA) diagnosed in adulthood: Varied clinical presentation, therapeutic approach and outcome. ( 29548537 )
2018
6
Vascular Network Inside the Hearta88- Collateral Flow on Color Doppler Echo in a Child With Anomalous Left Coronary Artery From the Pulmonary Artery (ALCAPA). ( 29628455 )
2018
7
Presence of reduced regional left ventricular function even in the absence of left ventricular wall scar tissue in the long term after repair of an anomalous left coronary artery from the pulmonary artery. ( 29091021 )
2018
8
Levosimendan for Pediatric Anomalous Left Coronary Artery From the Pulmonary Artery Undergoing Repair: A Single-Center Experience. ( 30155453 )
2018
9
An unusual presentation of anomalous left coronary artery from the pulmonary artery (ALCAPA) syndrome in a 70-year-old man: a case report. ( 30343670 )
2018
10
Bland-White-Garland syndrome on coronary CT angiography. ( 29636337 )
2018
11
Bland-White-Garland syndrome in a 39-year-old lumberjack. ( 29984813 )
2018
12
Multimodal Imaging of Anomalous Left Coronary Artery from the Pulmonary Artery in a 75-Year-Old Woman. ( 29276438 )
2017
13
Misdiagnosed anomalous left coronary artery from the pulmonary artery as endocardial fibroelastosis in infancy: A case series. ( 28614263 )
2017
14
Multimodality Imaging of Anomalous Left Coronary Artery from the Pulmonary Artery. ( 29093774 )
2017
15
Long-term outcome after anomalous left coronary artery from the pulmonary artery repair: a 40-year single-centre experience. ( 29182759 )
2017
16
Anomalous Left Coronary Artery from the Pulmonary Artery Presenting with Atypical Chest Pain in an Adult: A Case Report. ( 29062380 )
2017
17
Echocardiographic Diagnosis, Surgical Treatment, and Outcomes of Anomalous Left Coronary Artery from the Pulmonary Artery. ( 28651802 )
2017
18
Cardiac MRI T1 mapping in unrepaired anomalous left coronary artery from the pulmonary artery. ( 28554340 )
2017
19
Late presentation of an anomalous left coronary artery from the pulmonary artery treated with conservative surgical management with long-term cardiac magnetic resonance imaging follow-up. ( 28321308 )
2017
20
Adult Bland-White-Garland syndrome presenting as a sudden cardiac death: successful resuscitation, implantable cardioverter defibrillator and surgery. ( 25062269 )
2017
21
Nicorandil was an Effective Treatment Option for a Patient with Bland-White-Garland Syndrome. ( 28794372 )
2017
22
A case of successful bystander cardiopulmonary resuscitation of an adult with Bland-White-Garland syndrome. ( 29152274 )
2017
23
An adult case of Bland-White-Garland syndrome with collaterals from giant right coronary artery and bronchial artery. ( 30279793 )
2017
24
Whole Exome Sequencing in a Rare Disease: A Patient with Anomalous Left Coronary Artery from the Pulmonary Artery (Bland-White-Garland Syndrome). ( 27195969 )
2016
25
Bypassing the Pump: Midterm Follow-Up of an Off-Pump Technique for Anomalous Left Coronary Artery From the Pulmonary Artery. ( 27098608 )
2016
26
Midterm outcome after surgical correction of anomalous left coronary artery from the pulmonary artery. ( 27562655 )
2016
27
Anomalous left coronary artery from the pulmonary artery discovered following total anomalous pulmonary venous return repair: a rare entity. ( 27573031 )
2016
28
Anomalous Left Coronary Artery From the Pulmonary Artery in Infants and Toddlers Misdiagnosed as Myocarditis. ( 26414630 )
2016
29
A Rare Case of Anomalous Left Coronary Artery From the Pulmonary Artery (Bland-White-Garland Syndrome) in a 68-Year-Old Woman. ( 27401860 )
2016
30
Unusual Survival of Anomalous Left Coronary Artery From the Pulmonary Artery With Severe Rheumatic Mitral Stenosis in Septuagenarian Women: Foes Becoming Friends? ( 27635184 )
2016
31
A curious course of an intramural anomalous left coronary artery from the pulmonary artery. ( 27993364 )
2016
32
Contrast Media Delivery in the Assessment of Anomalous Left Coronary Artery From the Pulmonary Artery. ( 27146172 )
2016
33
Coronary Artery Bypass Grafting for an Anomalous Left Coronary Artery from the Pulmonary Artery in a 73-Year-Old Female. ( 27102973 )
2016
34
Surgical Treatment of an Anomalous Left Coronary Artery From the Pulmonary Artery in a Sexagenarian Woman. ( 26971237 )
2016
35
Temporary left ventricular assistance for extreme postoperative heart failure in two infants with Bland-White-Garland syndrome. ( 27785147 )
2016
36
Two adult cases of Bland-White-Garland syndrome with lethal arrhythmia due to coronary steal phenomenon during physical or mental stress. ( 30546646 )
2016
37
Oblique coronary artery prolongation approach in anomalous left coronary artery from the pulmonary artery in a low-birth-weight neonate. ( 25870360 )
2015
38
Repair of anomalous left coronary artery from the pulmonary artery in the modern era: preoperative predictors of immediate postoperative outcomes and long term cardiac follow-up. ( 25301273 )
2015
39
Takeuchi repair of anomalous left coronary artery from the pulmonary artery. ( 25843240 )
2015
40
Combined Non-Invasive Doppler Echocardiography and Coronary Computed Tomography Lead to Diagnosis of Anomalous Left Coronary Artery From the Pulmonary Artery (ALCAPA) Syndrome. ( 25739407 )
2015
41
Unusual late clinical manifestation of Bland-White-Garland syndrome as sudden cardiac death survival. ( 25412599 )
2015
42
Bland-White-Garland syndrome. ( 24890555 )
2015
43
Bland-White-Garland syndrome diagnosed by computed tomography. ( 26313868 )
2015
44
Mechanical circulatory support after surgical repair of Bland-White-Garland syndrome. A study of three cases. ( 26336486 )
2015
45
Repair of Bland-White-Garland Syndrome via a Modified Technique. ( 26504455 )
2015
46
Aneurysm of the Left Coronary Artery in Postoperative Bland-White-Garland Syndrome. ( 26770839 )
2015
47
Midterm results of left coronary artery reimplantation through the transverse sinus of the pericardium in adult Bland-White-Garland syndrome. ( 26943392 )
2015
48
Giant coronary artery aneurysm after takeuchi repair for anomalous left coronary artery from the pulmonary artery. ( 24169018 )
2014
49
Myocardial perfusion, scarring, and function in anomalous left coronary artery from the pulmonary artery syndrome: a long-term analysis using magnetic resonance imaging. ( 25130077 )
2014
50
Left ventricular thrombus formation after repair of anomalous left coronary artery from the pulmonary artery. ( 24668990 )
2014

Variations for Anomalous Left Coronary Artery from the Pulmonary Artery

Expression for Anomalous Left Coronary Artery from the Pulmonary Artery

Search GEO for disease gene expression data for Anomalous Left Coronary Artery from the Pulmonary Artery.

Pathways for Anomalous Left Coronary Artery from the Pulmonary Artery

GO Terms for Anomalous Left Coronary Artery from the Pulmonary Artery

Cellular components related to Anomalous Left Coronary Artery from the Pulmonary Artery according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 recycling endosome membrane GO:0055038 8.96 EHD1 PDIA3
2 platelet alpha granule lumen GO:0031093 8.62 PF4 VWF

Sources for Anomalous Left Coronary Artery from the Pulmonary Artery

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
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43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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