MCID: ANS006
MIFTS: 29

Anosognosia

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Anosognosia

MalaCards integrated aliases for Anosognosia:

Name: Anosognosia 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0060133
UMLS 71 C0234507

Summaries for Anosognosia

Disease Ontology : 12 An agnosia that is a loss of the ability to gain feedback about one's own condition or impairments.

MalaCards based summary : Anosognosia is related to amnestic disorder and anterograde amnesia, and has symptoms including other general symptoms An important gene associated with Anosognosia is ADAMTS2 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2). The drugs Donepezil and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, parietal lobe and testes.

Wikipedia : 74 Anosognosia is a deficit of self-awareness, a condition in which a person with a disability is unaware... more...

Related Diseases for Anosognosia

Diseases related to Anosognosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 amnestic disorder 30.4 BCHE APOE
2 anterograde amnesia 30.3 RTN4 APOE
3 cortical deafness 30.3 RTN4 BCHE
4 capgras syndrome 30.2 CDR1 BCHE ADAMTS2
5 aphasia 30.2 CBSL C9orf72 APOE ADAMTS2
6 simultanagnosia 29.8 CBSL APOE ADAMTS2
7 agraphia 29.8 CBSL C9orf72
8 dysgraphia 29.8 CBSL C9orf72
9 alexia 29.7 CBSL BCHE APOE
10 frontotemporal dementia 29.3 C9orf72 BCHE APOE
11 anton's syndrome 11.6
12 hemiplegia 11.0
13 alzheimer disease 10.9
14 dementia 10.6
15 cerebrovascular disease 10.5
16 stroke, ischemic 10.5
17 yemenite deaf-blind hypopigmentation syndrome 10.5
18 apraxia 10.4
19 cortical blindness 10.4
20 depression 10.4
21 paraneoplastic cerebellar degeneration 10.4 CDR2 CDR1
22 cerebellar degeneration 10.4 CDR2 CDR1
23 acute diffuse nephritis 10.4 CDR2 CDR1
24 retinitis pigmentosa 47 10.4 CDR2 CDR1
25 retinitis pigmentosa 57 10.3 CDR2 CDR1
26 visual agnosia 10.3 APOE ADAMTS2
27 denture stomatitis 10.3 CDR2 CDR1
28 agnosia 10.3
29 schuurs-hoeijmakers syndrome 10.2 CDR2 CDR1
30 cone-rod dystrophy 1 10.2 CDR2 CDR1
31 alcohol dependence 10.2
32 amyotrophic lateral sclerosis 1 10.2
33 schizophrenia 10.2
34 branchiootic syndrome 1 10.2
35 lateral sclerosis 10.2
36 brain injury 10.2
37 communicating hydrocephalus 10.2 APOE ADAMTS2
38 drug psychosis 10.1 BCHE ADAMTS2
39 drug-induced mental disorder 10.1 BCHE ADAMTS2
40 hand skill, relative 10.1
41 huntington disease 10.1
42 visual epilepsy 10.1
43 mood disorder 10.1
44 head injury 10.1
45 seizure disorder 10.1
46 traumatic brain injury 10.1
47 semantic dementia 10.1 C9orf72 APOE
48 finger agnosia 10.1 CBSL ADAMTS2
49 alzheimer disease 2 10.0 BCHE APOE
50 associative agnosia 10.0 C9orf72 BCHE

Graphical network of the top 20 diseases related to Anosognosia:



Diseases related to Anosognosia

Symptoms & Phenotypes for Anosognosia

UMLS symptoms related to Anosognosia:


other general symptoms

Drugs & Therapeutics for Anosognosia

Drugs for Anosognosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Donepezil Approved Phase 1 120014-06-4 3152
2 Neurotransmitter Agents Phase 1
3 Nootropic Agents Phase 1
4 Cholinergic Agents Phase 1
5 Cholinesterase Inhibitors Phase 1
6 Flutemetamol Investigational 637003-10-2
7 Radiopharmaceuticals

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Phase 1 Study of Aricept Plus a Behavioral Strategy to Improve Functional Tasks in Vascular Dementia Active, not recruiting NCT00457769 Phase 1 Donepezil and self-generated memory training;Donepezil and experimenter-administered memory training
2 FMRI of Anosognosia in Amnestic MCI and AD: Focus on Cortical Midline Structures Completed NCT00908999
3 ACT-HF: Attention, Cognition and Self-Management in Heart Failure Completed NCT01064765
4 Brain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of Life Completed NCT03589677
5 Enhancing Working Memory in Patients With Early Alzheimer's Disease Through the Enhancement of Dorsolateral Prefrontal Cortex Neuroplasticity: A TMS-EEG Study Completed NCT02537496
6 Anosognosia Evaluation After Cranocerebral Trauma Moderate to Severe Recruiting NCT02333006
7 The Clinical and Functional Imaging Effects of Transcranial Direct Current Stimulation (tDCS) on Illness Awareness in Schizophrenia Recruiting NCT02848885
8 Lack of Awareness of Symptoms (Anosognosia) in PD: An Observational Study to Examine the Effects of Anosognosia on Self-Reported Quality of Life for People With Parkinson's Recruiting NCT02561715
9 Assessing Efficacy of Neuropsychiatric Assessment and Treatment Protocols in Huntington's Disease Patients Recruiting NCT03417583
10 The Swedish BioFINDER 2 Study Recruiting NCT03174938
11 Cognitive and Cerebral Mechanisms of Anosognosia in Patients With Acquired Brain Damage: New Evaluation Strategies Based on Daily Tasks Enrolling by invitation NCT03712839
12 Clinical Assessment and Screening of Patients With Spatial Neglect Following Stroke Not yet recruiting NCT04072614

Search NIH Clinical Center for Anosognosia

Genetic Tests for Anosognosia

Anatomical Context for Anosognosia

MalaCards organs/tissues related to Anosognosia:

40
Brain, Parietal Lobe, Testes, Cortex, Heart, Prefrontal Cortex, Eye

Publications for Anosognosia

Articles related to Anosognosia:

(show top 50) (show all 719)
# Title Authors PMID Year
1
Hippocampal diaschisis contributes to anosognosia for hemiplegia: Evidence from lesion network-symptom-mapping. 61
31870945 2020
2
Evolution of anosognosia in alzheimer's disease and its relationship to amyloid. 61
31750553 2020
3
Novel Alzheimer's disease subtypes identified using a data and knowledge driven strategy. 61
31992745 2020
4
Anosognosia in patients with Alzheimer's disease: current perspectives. 61
31930617 2020
5
CADASIL presenting as late-onset mania with anosognosia. 61
31998484 2020
6
Anosognosia Is Associated With Greater Caregiver Burden and Poorer Executive Function in Huntington Disease. 61
31213121 2020
7
Understanding Anosognosia for Hemiplegia After Stroke. 61
31876873 2020
8
Understanding Anosognosia for Hemiplegia After Stroke. 61
30086101 2020
9
Delay in diagnosing patients with right-sided glioblastoma induced by hemispheric-specific clinical presentation. 61
31713017 2020
10
The behavioral presentation of an individual with a disordered sense of self. 61
31977238 2020
11
Dissociations between perception and awareness in hemianopia. 61
31929128 2020
12
Anton's syndrome: a rare and unusual form of blindness. 61
31801772 2019
13
Anosognosia and default mode subnetwork dysfunction in Alzheimer's disease. 61
31444942 2019
14
Neuropsychological Correlates of Anosognosia for Objective Functional Difficulties in Older Adults on the Mild Cognitive Impairment Spectrum. 61
31875876 2019
15
A case of somatoparaphrenia characterized by very mild somatosensory disturbance and absence of anosognosia for hemiplegia and personal neglect. 61
30979503 2019
16
Awareness of Chorea in Huntington's Disease. 61
31707371 2019
17
Functional and Pathological Correlates of Judgments of Learning in Cognitively Unimpaired Older Adults. 61
31696223 2019
18
In the here and now: Short term memory predictions are preserved in Alzheimer's disease. 61
31132694 2019
19
Explicit and implicit monitoring in neurodegeneration and stroke. 61
31575976 2019
20
Anosognosia for prospective and retrospective memory deficits: Assessment and theoretical considerations. 61
31219295 2019
21
The Phenomenology of Acute Anosognosia for Hemiplegia. 61
31662091 2019
22
[Rehabilitation of anosognosia in patients with unilateral visuospatial neglect]. 61
31364148 2019
23
Anosognosia of financial ability in mild cognitive impairment. 61
30968462 2019
24
Anosognosia for hemiplegia as a tripartite disconnection syndrome. 61
31383259 2019
25
Olfactory anosognosia is a predictor of cognitive decline and dementia conversion in Parkinson's disease. 61
31011798 2019
26
Evaluation of a performance-rating method to assess awareness of cognitive functioning in Huntington's disease. 61
31322031 2019
27
Measuring awareness in people with dementia: protocol for a scoping review. 61
31272501 2019
28
Functional Neural Correlates of Anosognosia in Mild Cognitive Impairment and Alzheimer's Disease: a Systematic Review. 61
31161466 2019
29
A combined therapy for limb apraxia and related anosognosia. 61
31210088 2019
30
Interaction between memory impairment and depressive symptoms can exacerbate anosognosia: a comparison of Alzheimer's disease with mild cognitive impairment. 61
29528693 2019
31
Long-term cognitive disability after traumatic brain injury: Contribution of the DEX relative questionnaires. 61
31116085 2019
32
Clinical Considerations in Physician-Assisted Death for Probable Alzheimer's Disease: Decision-Making Capacity, Anosognosia, and Suffering. 61
31275347 2019
33
Metacognition and self-awareness in Multiple Sclerosis. 61
30530267 2019
34
Online and offline awareness deficits: Anosognosia for spatial neglect. 61
29648845 2019
35
Bioccipital Lobe Hypoperfusion and Anton's Syndrome Resolution with Intravenous Thrombolysis. 61
30314761 2019
36
Anton's Syndrome associated with autotopagnosia. 61
30661390 2019
37
Insight across mental disorders: A multifaceted metacognitive phenomenon. 61
31115349 2019
38
Quality of Life in People with Young-Onset Dementia: A Nordic Two-Year Observational Multicenter Study. 61
30530973 2019
39
History of Anosognosia. 61
31220837 2019
40
Seneca and the First Description of Anton Syndrome. 61
29979335 2018
41
Anosognosia for chronic dysphagia. 61
30292345 2018
42
Anosognosia in degenerative brain diseases: The role of the right hemisphere and of its dominance for emotions. 61
30179807 2018
43
Patients' experiences of unilateral spatial neglect between stroke onset and discharge from inpatient rehabilitation: a thematic analysis of qualitative interviews. 61
30466328 2018
44
Over- and underestimation of motor ability after a stroke: Implications for anosognosia. 61
30098977 2018
45
Anosognosia for cognitive and behavioral symptoms in Parkinson's disease with mild dementia and mild cognitive impairment: Frequency and neuropsychological/neuropsychiatric correlates. 61
29709507 2018
46
Cortical thickness and metacognition in cognitively diverse older adults. 61
29878837 2018
47
The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia. 61
29866588 2018
48
Teaching NeuroImages: Distinct visual anosognosia after serial lesions of Meyer loop and the lateral geniculate body. 61
29967211 2018
49
Anosognosia. 61
29731103 2018
50
Metacognition of visuomotor decisions in conversion disorder. 61
29698734 2018

Variations for Anosognosia

Expression for Anosognosia

Search GEO for disease gene expression data for Anosognosia.

Pathways for Anosognosia

GO Terms for Anosognosia

Sources for Anosognosia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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