Aliases & Classifications for Anoxia

MalaCards integrated aliases for Anoxia:

Name: Anoxia 54 73

External Ids:

UMLS 73 C0003130

Summaries for Anoxia

NINDS : 54 Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow. Drowning, strangling, choking, suffocation, cardiac arrest, head trauma, carbon monoxide poisoning, and complications of general anesthesia can create conditions that can lead to cerebral hypoxia. Symptoms of mild cerebral hypoxia include inattentiveness, poor judgment, memory loss, and a decrease in motor coordination. Brain cells are extremely sensitive to oxygen deprivation and can begin to die within five minutes after oxygen supply has been cut off. When hypoxia lasts for longer periods of time, it can cause coma, seizures, and even brain death.  In brain death, there is no measurable activity in the brain, although cardiovascular function is preserved. Life support is required for respiration.

MalaCards based summary : Anoxia is related to ischemia and cerebral hypoxia, and has symptoms including anoxemia, cyanosis and dyspnea. An important gene associated with Anoxia is SIRT2 (Sirtuin 2), and among its related pathways/superpathways are Folate Metabolism and Photodynamic therapy-induced NF-kB survival signaling. The drugs Zinc and Amlodipine have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and heart, and related phenotypes are Strongly decreased CFP-tsO45G cell surface transport and endocrine/exocrine gland

Wikipedia : 76 The term anoxia means a total depletion in the level of oxygen, an extreme form of hypoxia or \"low... more...

Related Diseases for Anoxia

Graphical network of the top 20 diseases related to Anoxia:



Diseases related to Anoxia

Symptoms & Phenotypes for Anoxia

UMLS symptoms related to Anoxia:


anoxemia, cyanosis, dyspnea, signs and symptoms, respiratory, respiratory distress, labored breathing, symptoms

GenomeRNAi Phenotypes related to Anoxia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Strongly decreased CFP-tsO45G cell surface transport GR00360-A-2 8.92 CTGF EEF2K OXTR SIRT2

MGI Mouse Phenotypes related to Anoxia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.02 ACOX1 CTGF EEF2K ICAM1 NOS2 OXTR
2 cellular MP:0005384 9.95 CTGF EEF2K ICAM1 NOS2 SIRT2 SOD1
3 growth/size/body region MP:0005378 9.87 ACOX1 CTGF ICAM1 NOS2 OXTR SOD1
4 homeostasis/metabolism MP:0005376 9.86 SOD1 XDH ACOX1 CTGF EEF2K ICAM1
5 integument MP:0010771 9.7 CTGF ICAM1 NOS2 OXTR SIRT2 SOD1
6 muscle MP:0005369 9.35 ICAM1 NOS2 OXTR SOD1 XDH
7 neoplasm MP:0002006 9.02 ACOX1 ICAM1 NOS2 SIRT2 SOD1

Drugs & Therapeutics for Anoxia

Drugs for Anoxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 639)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 23994
2
Amlodipine Approved Phase 4,Phase 2,Phase 3 88150-42-9 2162
3
Sevoflurane Approved, Vet_approved Phase 4,Not Applicable 28523-86-6 5206
4
Dopamine Approved Phase 4,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
5
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
6
Budesonide Approved Phase 4,Phase 1 51333-22-3 63006 5281004
7
Succinylcholine Approved Phase 4 306-40-1 5314
8
Bosentan Approved, Investigational Phase 4,Phase 1 147536-97-8 104865
9
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
10
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Not Applicable 59467-70-8 4192
11
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 10102-43-9 145068 160954
12
Ibuprofen Approved Phase 4,Phase 2,Phase 1,Not Applicable 15687-27-1 3672
13
Sufentanil Approved, Investigational Phase 4,Not Applicable 56030-54-7 41693
14
Metoprolol Approved, Investigational Phase 4,Phase 2,Phase 3 37350-58-6, 51384-51-1 4171
15
Ipratropium Approved Phase 4 22254-24-6, 60205-81-4 43232
16
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 2078-54-8 4943
17
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
18
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 51-43-4 5816
19
Terbutaline Approved Phase 4 23031-25-6 5403
20
Adenosine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 58-61-7 60961
21
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 437-38-7 3345
22
Angiotensin II Approved, Investigational Phase 4,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
23
Acetylcysteine Approved, Investigational Phase 4,Not Applicable,Early Phase 1 616-91-1 12035
24
Fluticasone Approved, Experimental, Investigational Phase 4 90566-53-3 62924
25
Bromhexine Approved Phase 4 3572-43-8
26
Racepinephrine Approved Phase 4,Phase 2,Phase 3,Not Applicable 329-65-7 838
27
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
28
Etomidate Approved Phase 4 33125-97-2 36339 667484
29
Benzydamine Approved Phase 4 100-46-9, 642-72-8 7504
30
Ranibizumab Approved Phase 4,Not Applicable 347396-82-1 459903
31
Menthol Approved Phase 4,Phase 3,Phase 2,Not Applicable 2216-51-5 16666
32
Acetazolamide Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 59-66-5 1986
33
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
34
Memantine Approved, Investigational Phase 4,Phase 2 19982-08-2 4054
35
Captopril Approved Phase 4 62571-86-2 44093
36
Losartan Approved Phase 4,Phase 2 114798-26-4 3961
37
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
38
Bupivacaine Approved, Investigational Phase 4,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
39
Methazolamide Approved Phase 4,Phase 1,Phase 2 554-57-4 4100
40
Nifedipine Approved Phase 4 21829-25-4 4485
41
Ketorolac Approved Phase 4,Phase 1 74103-06-3, 66635-83-4 3826
42
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
43
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
44
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
45
Morphine Approved, Investigational Phase 4,Phase 2,Not Applicable 57-27-2 5288826
46
Oseltamivir Approved Phase 4,Phase 2 204255-11-8, 196618-13-0 65028
47
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
48
Lorazepam Approved Phase 4,Not Applicable 846-49-1 3958
49
Isoflurane Approved, Vet_approved Phase 4,Phase 3 26675-46-7 3763
50
Bisoprolol Approved Phase 4 66722-44-9 2405

Interventional clinical trials:

(show top 50) (show all 1317)
# Name Status NCT ID Phase Drugs
1 Intermittent Hypoxia 2: Cardiovascular and Metabolism Unknown status NCT02058823 Phase 4 Placebo;Placebo;Valsartan;Amlodipine
2 Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or Hypoxia Unknown status NCT01449253 Phase 4 Sildenafil;Bosentan
3 Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery Unknown status NCT02133638 Phase 4 Sevoflurane;Propofol
4 Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children Unknown status NCT02205580 Phase 4 continuous intravenous sufentanil 0.02μg•kg-1•h-1 infusion;continuous intravenous sufentanil 0.03μg•kg-1•h-1 infusion;continuous intravenous sufentanil 0.04μg•kg-1•h-1 infusion
5 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4 sodium bicarbonate
6 Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage Unknown status NCT01180192 Phase 4 oxygen
7 Home Oxygen Therapy in Bronchiolitis Unknown status NCT01216553 Phase 4
8 Effect of Acute Hyperglycemia on Renal Tissue Oxygenation Unknown status NCT02346149 Phase 4
9 CPAP in Liver Transplant Unknown status NCT00510770 Phase 4
10 Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation Unknown status NCT01595399 Phase 4 atropine;Placebo
11 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure Unknown status NCT00668408 Phase 4
12 AZ, MZ, and the Pulmonary System Response to Hypoxia Completed NCT02760121 Phase 4 Acetazolamide;Methazolamide;Placebo
13 5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females Completed NCT02356107 Phase 4 5-hydroxytryptophan and Creatine monohydrate
14 Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation Completed NCT01692821 Phase 4 100% oxygen breathing;15% oxygen in N2 breathing;12% oxygen in N2 breathing
15 Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy Completed NCT02628106 Phase 4 Lipo-PGE1
16 Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers Completed NCT01873612 Phase 4
17 Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects. Completed NCT00924833 Phase 4 placebo;Carvedilol;Nebivolol
18 CPAP in SAHS Patients With Hypertension Completed NCT02398032 Phase 4
19 Muscle Fatigue and Carbonic Anhydrase Inhibitors Completed NCT02758470 Phase 4 Acetazolamide;Methazolamide
20 Ambulatory Oxygen Effects on Muscles in COPD Completed NCT01722370 Phase 4 Oxygen;Medical air equivalent
21 Doxapram as an Additive to Propofol Sedation in Sedation for ERCP Completed NCT02171910 Phase 4 Doxapram;Placebo
22 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
23 Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure Completed NCT00517725 Phase 4 carvedilol;bisoprolol;Nebivolol
24 The Effect of Nasal Cannula During the First 2 Hours Postoperative in Patient Undergoing Thoracotomy Completed NCT01725464 Phase 4
25 Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate Completed NCT00880672 Phase 4 dutasteride
26 Influence of Cardiopulmonary Bypass, and Sevoflurane or Propofol Anesthesia, on Tissue Oxygen Saturation. Completed NCT02593448 Phase 4
27 Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring Completed NCT01327677 Phase 4 Fentanyl;Fentanyl
28 Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation Completed NCT01260662 Phase 4 Propofol;1:1 Propofol/Ketamine;4:1 Propofol/Ketamine
29 Treatment of Patients With the Obstructive Sleep Apnea Syndrome at Altitude Completed NCT00714740 Phase 4 acetazolamide
30 Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy Completed NCT02602743 Phase 4 Remifentanyl;Propofol;Ketamine
31 Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress Completed NCT01830335 Phase 4 Indomethacin;Placebo
32 The Use of Statins for Myocardial Death Prevention Completed NCT00772564 Phase 4 Atorvastatin
33 Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP. Completed NCT00360659 Phase 4
34 Preventive Effect of the PRetreatment With Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients With RenaL Dysfunction UndEergoing Coronary Angiography (PRINCIPLE Study) Completed NCT01103336 Phase 4 pretreatment with intravenous nicorandil vs. placebo before coronary angiography
35 Increased Renal Oxygenation and Angiotensin Converting Enzyme Inhibition Completed NCT01545479 Phase 4 captopril 25mg
36 Ranibizumab in Patients With Branch Retinal Vein Occlusion Completed NCT01027481 Phase 4 Lucentis
37 Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude Completed NCT02024386 Phase 4 Riociguat
38 Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation Completed NCT02962999 Phase 4 Ketamine;Saline
39 To Evaluate the Effect of Chlorhexidine-benzidamine Administration Completed NCT03253497 Phase 4 Chlorobenzene Liquid
40 The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia Completed NCT01091571 Phase 4 Dipyridamole;Placebo
41 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4 early enteral nutrition;Delayed enteral nutrition
42 Erythropoietin in the Prevention of Acute Mountain Sickness Completed NCT01665781 Phase 4 Erythropoietin
43 Acute Effect of Pulmonary Desufflation on Cardiac Performance in COPD Patients Completed NCT01996124 Phase 4 Indacaterol Fumarate;Placebo
44 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Completed NCT00560586 Phase 4 Budesonide;placebo
45 Effect-site Concentration of Remifentanil for Smooth Induction With Desflurane Completed NCT02379715 Phase 4 Remifentanil;Desflurane
46 Bispectral Index and Clinical Parameters Evaluation in Dental Procedures Completed NCT02671578 Phase 4 Nitrous Oxide
47 Investigating the Accuracy of the Home Glucose Monitors in Hypoglycemia Completed NCT01013402 Phase 4 Human insulin;Human Insulin
48 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
49 Optiflow® to Prevent Post-Extubation Hypoxemia afteR Abdominal Surgery (the OPERA Trial) Completed NCT01887015 Phase 4
50 Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy Completed NCT01470170 Phase 4 Alfentanil;Normal saline;Propofol

Search NIH Clinical Center for Anoxia

Genetic Tests for Anoxia

Anatomical Context for Anoxia

MalaCards organs/tissues related to Anoxia:

41
Lung, Brain, Heart, Kidney, Prostate, Liver, Endothelial

Publications for Anoxia

Articles related to Anoxia:

(show top 50) (show all 704)
# Title Authors Year
1
Capsaicin prevents mitochondrial damage, protects cardiomyocytes subjected to anoxia/reoxygenation injury mediated by 14-3-3I^/Bcl-2. ( 29175072 )
2018
2
Prazosin protects myocardial cells against anoxia-reoxygenation injury via the extracellular signala89regulated kinase signaling pathway. ( 29207167 )
2018
3
The role of the ATPase inhibitor factor 1 (IF<sub>1</sub>) in cancer cells adaptation to hypoxia and anoxia. ( 29097244 )
2018
4
Paralytic hypo-energetic state facilitates anoxia tolerance despite ionic imbalance in adult <i>Drosophila melanogaster</i>. ( 29615525 )
2018
5
Reversible growth arrest of 3D tumor spheroids stored in oxygen absorber-induced anoxia. ( 29434901 )
2018
6
Rat astrocytes during anoxia: Secretome profile of cytokines and chemokines. ( 29863786 )
2018
7
The protective effect of Hif3a RNA interference and HIF-prolyl hydroxylase inhibition on cardiomyocytes under anoxia-reoxygenation. ( 29660430 )
2018
8
Temperature-dependent metabolic adaptation of Triticum aestivum seedlings to anoxia. ( 29670175 )
2018
9
The evaluation of anoxia responsive E2F DNA binding activity in the red eared slider turtle, <i>Trachemys scripta elegans</i>. ( 29770276 )
2018
10
Thallium isotopes reveal protracted anoxia during the Toarcian (Early Jurassic) associated with volcanism, carbon burial, and mass extinction. ( 29891692 )
2018
11
Multiple episodes of extensive marine anoxia linked to global warming and continental weathering following the latest Permian mass extinction. ( 29651454 )
2018
12
50 Years Ago in The Journal of Pediatrics: The Effect of Pretreatment with Pentobarbital, Meperidine, or Hyperbaric Oxygen on the Response to Anoxia and Resuscitation in Newborn Rabbits. ( 29576175 )
2018
13
Effects of anoxia on survival and gene expression in Bactrocera dorsalis. ( 29630918 )
2018
14
High-Mobility Group Box 1 Protein Regulates Autophagy in LO2 Cells Following Anoxia-Reoxygenation Injury. ( 29880383 )
2018
15
Assessment of possible solid-phase phosphate sorbents to mitigate eutrophication: Influence of pH and anoxia. ( 29734619 )
2018
16
Two new flavonoid-triterpene saponin meroterpenoids from Clinopodium chinense and their protective effects against anoxia/reoxygenation-induced apoptosis in H9c2 cells. ( 29782903 )
2018
17
Combating hypoxia/anoxia at sediment-water interfaces: A preliminary study of oxygen nanobubble modified clay materials. ( 29754089 )
2018
18
-Characterization of pyruvate kinase from the anoxia tolerant turtle, <i>Trachemys scripta elegans</i>: a potential role for enzyme methylation during metabolic rate depression. ( 29900073 )
2018
19
Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle. ( 29382574 )
2018
20
Hormetic benefits of prior anoxia exposure in buffering anoxia stress in a soil-pupating insect. ( 29367272 )
2018
21
Protective effects of echinacoside against anoxia/reperfusion injury in H9c2 cells via up-regulating p-AKT and SLC8A3. ( 29763795 )
2018
22
Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). ( 29402754 )
2018
23
Early Palaeozoic ocean anoxia and global warming driven by the evolution of shallow burrowing. ( 29967319 )
2018
24
Abrupt global-ocean anoxia during the Late Ordovician-early Silurian detected using uranium isotopes of marine carbonates. ( 29784792 )
2018
25
Sodium pump alpha-2 subunit (ATP1A2) alleviates cardiomyocyte anoxia/reoxygenation injury via inhibition of endoplasmic reticulum stress-related apoptosis. ( 29394489 )
2018
26
Extensive marine anoxia during the terminal Ediacaran Period. ( 29938217 )
2018
27
Editorial: Eukaryotic Microbes Store Nitrate for &amp;quot;Breathing&amp;quot; in Anoxia. ( 29375489 )
2017
28
Charcoal evidence that rising atmospheric oxygen terminated Early Jurassic ocean anoxia. ( 28497785 )
2017
29
Small noncoding RNA expression during extreme anoxia tolerance of annual killifish (Austrofundulus limnaeus) embryos. ( 28802262 )
2017
30
Ocean deoxygenation, the global phosphorus cycle and the possibility of human-caused large-scale ocean anoxia. ( 28784709 )
2017
31
Effect of total flavonoid in rabdosia rubescens on tolerant mice models under cerebral anoxia. ( 29551926 )
2017
32
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat. ( 28428423 )
2017
33
Surviving anoxia in marine sediments: The metabolic response of ubiquitous benthic foraminifera (Ammonia tepida). ( 28562648 )
2017
34
Promotion of anoxia-reoxygenation-induced inflammation and permeability enhancement by nicotinamide phosphoribosyltransferase-activated MAPK signaling in human umbilical vein endothelial cells. ( 29104667 )
2017
35
White - cGMP Interaction Promotes Fast Locomotor Recovery from Anoxia in Adult Drosophila. ( 28060942 )
2017
36
GATA1 activated lncRNA (Galont) promotes anoxia/reoxygenation-induced autophagy and cell death in cardiomyocytes by sponging miR-338. ( 29247537 )
2017
37
An Efficient and Reliable Assay for Investigating the Effects of Hypoxia/Anoxia on Drosophila. ( 28866769 )
2017
38
I^-Aminobutyric Acid (GABA) Accumulation in Tea (Camellia sinensis L.) through the GABA Shunt and Polyamine Degradation Pathways under Anoxia. ( 28355482 )
2017
39
Exploration of low temperature microRNA function in an anoxia tolerant vertebrate ectotherm, the red eared slider turtle (Trachemys scripta elegans). ( 28689715 )
2017
40
Effects of erythropoietin on astrocytes and brain endothelial cells in primary culture during anoxia depend on simultaneous signaling by other cytokines and on duration of anoxia. ( 29180303 )
2017
41
Re-oxygenation after anoxia induces brain cell death and memory loss in the anoxia-tolerant crucian carp. ( 29093186 )
2017
42
Effect of Calcium-sensing Receptor on the Apoptosis of Rat Spinal Cord Neurons in Anoxia/Reoxygenation Injury and Its Significance. ( 29125103 )
2017
43
SYK protects cardiocytes against anoxia and hypoglycemia-induced injury in ischemic heart failure. ( 28869869 )
2017
44
Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1. ( 29435095 )
2017
45
Intervention effect of total flavonoids of ilex pubesceus on tolerant rat models under cerebral anoxia. ( 29551938 )
2017
46
Sex differences in somatic and sensory motor development after neonatal anoxia in Wistar rats. ( 28709915 )
2017
47
VDAC1 deacetylation is involved in the protective effects of resveratrol against mitochondria-mediated apoptosis in cardiomyocytes subjected to anoxia/reoxygenation injury. ( 28826100 )
2017
48
AMP-activated protein kinase protects against anoxia in Drosophila melanogaster. ( 28916374 )
2017
49
The effects of pH and Pi on tension and Ca(2+) sensitivity of ventricular myofilaments from the anoxia-tolerant painted turtle. ( 28939564 )
2017
50
Inter- and intraspecific variability in physiological traits and post-anoxia recovery of photosynthetic efficiency in grasses under oxygen deprivation. ( 28767128 )
2017

Variations for Anoxia

Expression for Anoxia

Search GEO for disease gene expression data for Anoxia.

Pathways for Anoxia

GO Terms for Anoxia

Cellular components related to Anoxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.56 ACOX1 CTGF ICAM1 KCNJ5 NOS2 OXTR
2 peroxisome GO:0005777 8.92 ACOX1 NOS2 SOD1 XDH

Biological processes related to Anoxia according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.83 ACOX1 NOS2 SOD1 XDH
2 response to drug GO:0042493 9.72 ICAM1 OXTR SOD1
3 negative regulation of gene expression GO:0010629 9.63 CTGF NOS2 XDH
4 positive regulation of synapse assembly GO:0051965 9.57 EEF2K OXTR
5 response to peptide hormone GO:0043434 9.56 CTGF OXTR
6 lactation GO:0007595 9.54 OXTR XDH
7 ovarian follicle development GO:0001541 9.51 ICAM1 SOD1
8 reactive oxygen species metabolic process GO:0072593 9.49 CTGF SOD1
9 response to amino acid GO:0043200 9.48 CTGF ICAM1
10 positive regulation of vasoconstriction GO:0045907 9.43 ICAM1 OXTR
11 negative regulation of protein catabolic process GO:0042177 9.4 NOS2 SIRT2
12 cell aging GO:0007569 9.37 ICAM1 SOD1
13 response to organic cyclic compound GO:0014070 9.33 CTGF ICAM1 OXTR
14 superoxide metabolic process GO:0006801 9.32 NOS2 SOD1
15 response to copper ion GO:0046688 9.26 ICAM1 SOD1
16 response to anoxia GO:0034059 8.96 CTGF OXTR
17 response to amphetamine GO:0001975 8.8 ICAM1 OXTR SOD1

Molecular functions related to Anoxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.26 ACOX1 NOS2 SOD1 XDH
2 flavin adenine dinucleotide binding GO:0050660 8.8 ACOX1 NOS2 XDH

Sources for Anoxia

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