MCID: ANT022
MIFTS: 26

Anterior Cranial Fossa Meningioma

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Anterior Cranial Fossa Meningioma

MalaCards integrated aliases for Anterior Cranial Fossa Meningioma:

Name: Anterior Cranial Fossa Meningioma 11 14 71
Meningioma of the Anterior Fossa 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4436
NCIt 49 C5286
UMLS 71 C1332301

Summaries for Anterior Cranial Fossa Meningioma

MalaCards based summary: Anterior Cranial Fossa Meningioma, also known as meningioma of the anterior fossa, is related to meningioma, familial and full schwannomatosis, and has symptoms including headache and seizures. An important gene associated with Anterior Cranial Fossa Meningioma is TRAF7 (TNF Receptor Associated Factor 7), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and Hedgehog signaling pathway. Affiliated tissues include brain, and related phenotypes are Increased proliferation and neoplasm

Related Diseases for Anterior Cranial Fossa Meningioma

Diseases related to Anterior Cranial Fossa Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 28.1 TRAF7 SUFU SMARCE1 SMARCB1 PTCH1 POLR2A
2 full schwannomatosis 10.2 SMARCB1 NF2
3 posterior pituitary gland neoplasm 10.2 SMARCB1 NF2
4 intraneural perineurioma 10.2 TRAF7 NF2
5 peripheral nerve schwannoma 10.2 SMARCB1 NF2
6 pineal region meningioma 10.2 SMARCB1 NF2
7 petroclival meningioma 10.2 TRAF7 NF2
8 plexiform schwannoma 10.2 SMARCB1 NF2
9 schwannomatosis 1 10.2 SMARCB1 NF2
10 cerebellopontine angle tumor 10.2 SMARCB1 NF2
11 cellular schwannoma 10.2 SMARCB1 NF2
12 cerebellopontine angle meningioma 10.2 SMARCE1 NF2
13 atypical neurofibroma 10.2 SMARCB1 NF2
14 optic nerve neoplasm 10.2 SMARCB1 NF2
15 melanotic neurilemmoma 10.2 SMARCB1 NF2
16 schwannoma of twelfth cranial nerve 10.2 SMARCB1 NF2
17 hypoglossal nerve disease 10.2 SMARCB1 NF2
18 spinal cord ependymoma 10.2 SMARCB1 NF2
19 cranial nerve malignant neoplasm 10.2 SMARCB1 NF2
20 anaplastic ependymoma 10.2 SMARCB1 NF2
21 plexiform neurofibroma 10.1 SMARCB1 NF2
22 high grade ependymoma 10.1 SMARCB1 NF2
23 cerebral ventricle cancer 10.1 SMARCB1 NF2
24 optic nerve sheath meningioma 10.1 TRAF7 SMARCB1 NF2
25 breast cancer 10.1
26 dementia, lewy body 10.1
27 parkinsonism 10.1
28 psychotic disorder 10.1
29 chordoid meningioma 10.1 TRAF7 SMARCB1 NF2
30 melanotic medulloblastoma 10.1 SUFU SMARCB1
31 foramen magnum meningioma 10.1 TRAF7 POLR2A NF2
32 psammomatous meningioma 10.1 TRAF7 POLR2A NF2
33 sphenoorbital meningioma 10.1 TRAF7 SMARCE1 NF2
34 microcystic meningioma 10.1 TRAF7 SMARCE1 NF2
35 cerebrospinal fluid leak 10.1
36 solitary fibrous tumor/hemangiopericytoma 10.1 TRAF7 SMARCE1 SMARCB1
37 clark-baraitser syndrome 10.1 SMARCE1 SMARCB1
38 cerebrum cancer 10.1 SMARCB1 NF2
39 supratentorial cancer 10.1 SMARCB1 NF2
40 foster-kennedy syndrome 10.0 MAL2 HOXA6
41 petrous apex meningioma 10.0 NF2 EPB41
42 autosomal dominant intellectual developmental disorder 10.0 SMARCE1 SMARCB1
43 small intestine leiomyoma 10.0 PTCH1 NF2
44 tuberculum sellae meningioma 10.0 TRAF7 NF2 EPB41
45 childhood meningioma 10.0 TRAF7 SMARCE1 SMARCB1 NF2
46 sella turcica neoplasm 10.0 TRAF7 NF2 EPB41
47 spinal cancer 10.0 TRAF7 SMARCE1 SMARCB1 NF2
48 cavernous sinus meningioma 9.9 TRAF7 SMARCE1 POLR2A NF2
49 intraventricular meningioma 9.9 TRAF7 SMARCE1 POLR2A NF2
50 tinea capitis 9.9 PTCH1 NF2

Graphical network of the top 20 diseases related to Anterior Cranial Fossa Meningioma:



Diseases related to Anterior Cranial Fossa Meningioma

Symptoms & Phenotypes for Anterior Cranial Fossa Meningioma

UMLS symptoms related to Anterior Cranial Fossa Meningioma:


headache; seizures

GenomeRNAi Phenotypes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Anterior Cranial Fossa Meningioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.43 KLF4 NF2 POLR2A PTCH1 SMARCB1 SUFU
2 digestive/alimentary MP:0005381 9.1 KLF4 NF2 POLR2A PTCH1 SMARCB1 SUFU

Drugs & Therapeutics for Anterior Cranial Fossa Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Analysis of Post Surgical Response in A Fifty-Six Year Old Female With An Incidental Large Left Anterior Cranial Fossa Meningioma Completed NCT00945230

Search NIH Clinical Center for Anterior Cranial Fossa Meningioma

Genetic Tests for Anterior Cranial Fossa Meningioma

Anatomical Context for Anterior Cranial Fossa Meningioma

Organs/tissues related to Anterior Cranial Fossa Meningioma:

MalaCards : Brain

Publications for Anterior Cranial Fossa Meningioma

Articles related to Anterior Cranial Fossa Meningioma:

# Title Authors PMID Year
1
Minimally invasive nummular approach to a giant meningioma of the anterior fossa. 62
35673653 2022
2
Multifocal spinal glioblastoma and leptomeningeal carcinomatosis in an elderly male with hydrocephalus and myelopathy. 62
34992912 2021
3
Anatomical Variations in the Location of Veins Draining Into the Anterior Superior Sagittal Sinus: Implications for the Transbasal Approach. 62
31748805 2020
4
Secondary Parkinsonism Due to a Large Anterior Cranial Fossa Meningioma. 62
31139580 2019
5
The Radiographic Effects of Surgical Approach and Use of Retractors on the Brain After Anterior Cranial Fossa Meningioma Resection. 62
29367000 2018
6
Incidental finding of anterior cranial fossa meningioma on 18F-fluoride PET/CT. 62
24096998 2013
7
Nasoethmoid schwannoma with intracranial extension. Case report and review of literature. 62
19234915 2009
8
Psychiatric symptoms and an anterior cranial fossa meningioma. 62
9861864 1998

Variations for Anterior Cranial Fossa Meningioma

Expression for Anterior Cranial Fossa Meningioma

Search GEO for disease gene expression data for Anterior Cranial Fossa Meningioma.

Pathways for Anterior Cranial Fossa Meningioma

GO Terms for Anterior Cranial Fossa Meningioma

Cellular components related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nBAF complex GO:0071565 9.62 SMARCE1 SMARCB1
2 RSC-type complex GO:0016586 9.56 SMARCE1 SMARCB1
3 npBAF complex GO:0071564 9.46 SMARCE1 SMARCB1
4 brahma complex GO:0035060 9.26 SMARCE1 SMARCB1
5 bBAF complex GO:0140092 8.92 SMARCE1 SMARCB1

Biological processes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleosome disassembly GO:0006337 9.46 SMARCE1 SMARCB1
2 negative regulation of DNA-binding transcription factor activity GO:0043433 9.35 SUFU PTCH1 KLF4
3 positive regulation of cell differentiation GO:0045597 9.1 SMARCE1 SMARCB1 NF2

Sources for Anterior Cranial Fossa Meningioma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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