MCID: ANT022
MIFTS: 32

Anterior Cranial Fossa Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Anterior Cranial Fossa Meningioma

MalaCards integrated aliases for Anterior Cranial Fossa Meningioma:

Name: Anterior Cranial Fossa Meningioma 12 15 73
Meningioma of the Anterior Fossa 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4436
NCIt 50 C5286
UMLS 73 C1332301

Summaries for Anterior Cranial Fossa Meningioma

MalaCards based summary : Anterior Cranial Fossa Meningioma, also known as meningioma of the anterior fossa, is related to tracheal stenosis and tracheal disease, and has symptoms including headache and seizures. An important gene associated with Anterior Cranial Fossa Meningioma is PGRMC1 (Progesterone Receptor Membrane Component 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Folate Metabolism. Affiliated tissues include brain, and related phenotypes are Increased proliferation and cardiovascular system

Related Diseases for Anterior Cranial Fossa Meningioma

Diseases related to Anterior Cranial Fossa Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 tracheal stenosis 10.8 PGRMC1 RHNO1
2 tracheal disease 10.8 PGRMC1 RHNO1
3 cecal disease 10.7 CHGA PGRMC1
4 tanycytic ependymoma 10.7 CHGA NF2
5 lung meningioma 10.7 NF2 PGR
6 petrous apex meningioma 10.6 KANTR PGRMC1
7 foramen magnum meningioma 10.6 KANTR NF2
8 benign meningioma 10.6 NF2 PGR
9 clear cell meningioma 10.6 CHGA PGR
10 malignant skin fibrous histiocytoma 10.6 CHGA F7
11 pancreatic serous cystadenoma 10.6 CHGA PGR
12 substernal goiter 10.5 F7 KANTR
13 malignant dermis tumor 10.5 CHGA F7
14 facial nerve disease 10.5 KANTR NF2
15 dermoid cyst 10.5 CHGA PGR
16 visual agnosia 10.5 F7 KANTR
17 chronic myocardial ischemia 10.5 CHGA PLG
18 cerebral convexity meningioma 10.5 NF2 TP53
19 conjugate gaze palsy 10.5 F3 PLG
20 peritoneal mesothelioma 10.5 NF2 PGR
21 spinal cancer 10.5 NF2 TP53
22 chordoid glioma 10.4 NF2 TP53
23 cerebellopontine angle tumor 10.4 KANTR NF2
24 malignant ependymoma 10.4 NF2 TP53
25 radiation cystitis 10.4 F7 KANTR
26 cellular ependymoma 10.4 CHGA TP53
27 corneal abscess 10.4 PGR PLG
28 hemophilia a 10.4 F3 F7
29 atypical follicular adenoma 10.4 CHGA TP53
30 small cell sarcoma 10.4 NF2 TP53
31 hemometra 10.4 F3 KANTR
32 conjunctival disease 10.4 PLG RHNO1
33 vertebral artery occlusion 10.4 F3 PLG
34 lemierre's syndrome 10.4 F3 PLG
35 acute anterolateral myocardial infarction 10.3 KANTR PLG
36 posterolateral myocardial infarction 10.3 KANTR PLG
37 facial neuralgia 10.3 KANTR PLG
38 cerebral arteritis 10.3 KANTR PLG
39 shwartzman phenomenon 10.3 F3 KANTR
40 pulmonary blastoma 10.3 CHGA TP53
41 apical myocardial infarction 10.3 KANTR PLG
42 tubular adenocarcinoma 10.3 CHGA PGR
43 optic nerve neoplasm 10.3 NF2 TP53
44 endometrium carcinoma in situ 10.3 PGR TP53
45 breast papillary carcinoma 10.3 CHGA PGR
46 vestibular gland benign neoplasm 10.3 PGR TP53
47 pleomorphic xanthoastrocytoma 10.3 CHGA TP53
48 alveolar periostitis 10.3 KANTR PLG
49 bartholin's gland adenoma 10.3 PGR TP53
50 intermediate coronary syndrome 10.3 F3 PLG

Graphical network of the top 20 diseases related to Anterior Cranial Fossa Meningioma:



Diseases related to Anterior Cranial Fossa Meningioma

Symptoms & Phenotypes for Anterior Cranial Fossa Meningioma

UMLS symptoms related to Anterior Cranial Fossa Meningioma:


headache, seizures

GenomeRNAi Phenotypes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 TP53

MGI Mouse Phenotypes related to Anterior Cranial Fossa Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.87 CHGA F2 F3 F7 PGR PLG
2 mortality/aging MP:0010768 9.81 F7 NF2 PGR PGRMC1 PLG TP53
3 integument MP:0010771 9.73 F2 F3 NF2 PGR PLG TP53
4 neoplasm MP:0002006 9.35 F3 NF2 PGR PLG TP53
5 reproductive system MP:0005389 9.17 CHGA F2 NF2 PGR PGRMC1 PLG

Drugs & Therapeutics for Anterior Cranial Fossa Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Actigraphic Measurement of a Neurosurgical Procedure Completed NCT00945230 Not Applicable

Search NIH Clinical Center for Anterior Cranial Fossa Meningioma

Genetic Tests for Anterior Cranial Fossa Meningioma

Anatomical Context for Anterior Cranial Fossa Meningioma

MalaCards organs/tissues related to Anterior Cranial Fossa Meningioma:

41
Brain

Publications for Anterior Cranial Fossa Meningioma

Articles related to Anterior Cranial Fossa Meningioma:

# Title Authors Year
1
The Radiographic Effects of Surgical Approach and Use of Retractors on the Brain After Anterior Cranial Fossa Meningioma Resection. ( 29367000 )
2018
2
Incidental finding of anterior cranial fossa meningioma on 18F-fluoride PET/CT. ( 24096998 )
2013
3
Psychiatric symptoms and an anterior cranial fossa meningioma. ( 9861864 )
1998

Variations for Anterior Cranial Fossa Meningioma

Expression for Anterior Cranial Fossa Meningioma

Search GEO for disease gene expression data for Anterior Cranial Fossa Meningioma.

Pathways for Anterior Cranial Fossa Meningioma

GO Terms for Anterior Cranial Fossa Meningioma

Cellular components related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type peptidase complex GO:1905286 8.62 F3 F7

Biological processes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 cellular response to ionizing radiation GO:0071479 9.52 RHNO1 TP53
2 positive regulation of reactive oxygen species metabolic process GO:2000379 9.51 F2 TP53
3 signal peptide processing GO:0006465 9.49 F2 F7
4 fibrinolysis GO:0042730 9.48 F2 PLG
5 positive regulation of blood coagulation GO:0030194 9.46 F2 F7
6 positive regulation of positive chemotaxis GO:0050927 9.43 F3 F7
7 peptidyl-glutamic acid carboxylation GO:0017187 9.4 F2 F7
8 negative regulation of fibrinolysis GO:0051918 9.37 F2 PLG
9 blood coagulation, extrinsic pathway GO:0007598 9.32 F3 F7
10 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.26 F3 F7
11 blood coagulation GO:0007596 9.26 F2 F3 F7 PLG
12 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway GO:1900738 9.16 CHGA F2
13 hemostasis GO:0007599 8.92 F2 F3 F7 PLG

Molecular functions related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 9.16 PGR PGRMC1
2 serine-type peptidase activity GO:0008236 9.13 F2 F7 PLG
3 serine-type endopeptidase activity GO:0004252 8.92 F2 F3 F7 PLG

Sources for Anterior Cranial Fossa Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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