MCID: ANT022
MIFTS: 35

Anterior Cranial Fossa Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Anterior Cranial Fossa Meningioma

MalaCards integrated aliases for Anterior Cranial Fossa Meningioma:

Name: Anterior Cranial Fossa Meningioma 12 15 73
Meningioma of the Anterior Fossa 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4436
NCIt 50 C5286
UMLS 73 C1332301

Summaries for Anterior Cranial Fossa Meningioma

MalaCards based summary : Anterior Cranial Fossa Meningioma, also known as meningioma of the anterior fossa, is related to tracheal disease and cecal disease, and has symptoms including seizures and headache. An important gene associated with Anterior Cranial Fossa Meningioma is PGRMC1 (Progesterone Receptor Membrane Component 1), and among its related pathways/superpathways are Selenium Micronutrient Network and Microglia Activation During Neuroinflammation: Overview. Affiliated tissues include brain, lung and colon, and related phenotypes are Increased proliferation and cardiovascular system

Related Diseases for Anterior Cranial Fossa Meningioma

Diseases related to Anterior Cranial Fossa Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 212)
# Related Disease Score Top Affiliating Genes
1 tracheal disease 10.3 PGRMC1 RHNO1
2 cecal disease 10.3 CHGA PGRMC1
3 malignant skin fibrous histiocytoma 10.3 CHGA F7
4 chronic maxillary sinusitis 10.3 RHNO1 SYP
5 anaplastic ependymoma 10.3 NF2 SYP
6 carcinoid tumors, intestinal 10.2 CHGA SYP
7 respiratory system benign neoplasm 10.2 CHGA SYP
8 central neurocytoma 10.2 CHGA SYP
9 cranial nerve malignant neoplasm 10.2 CHGA SYP
10 papillary ependymoma 10.2 CHGA SYP
11 gastric squamous cell carcinoma 10.2 CHGA SYP
12 gastric small cell carcinoma 10.2 CHGA SYP
13 pancreatoblastoma 10.2 CHGA SYP
14 non-functioning pancreatic endocrine tumor 10.2 CHGA SYP
15 binswanger's disease 10.2 CHGA SYP
16 carcinoid syndrome 10.2 CHGA SYP
17 horseshoe kidney 10.2 CHGA SYP
18 subependymoma 10.2 CHGA SYP
19 benign meningioma 10.2 NF2 PGR
20 ureter small cell carcinoma 10.2 CHGA SYP
21 esophageal neuroendocrine tumor 10.2 CHGA SYP
22 urinary bladder small cell neuroendocrine carcinoma 10.2 CHGA SYP
23 ovarian large-cell neuroendocrine carcinoma 10.2 CHGA SYP
24 dermoid cyst 10.2 CHGA PGR
25 facial nerve disease 10.2 KANTR NF2
26 auditory system cancer 10.2 CHGA SYP
27 adenoma of the pancreas 10.2 CHGA SYP
28 acinar cell cystadenocarcinoma 10.2 CHGA SYP
29 peritoneal serous adenocarcinoma 10.2 CHGA SYP
30 gallbladder small cell carcinoma 10.2 CHGA SYP
31 primary hepatic neuroendocrine carcinoma 10.2 CHGA SYP
32 small cell carcinoma of the bladder 10.2 CHGA SYP
33 spermatocele 10.2 PGR SYP
34 perivascular epithelioid cell tumor 10.2 PGR SYP
35 gastrointestinal neuroendocrine tumor 10.2 CHGA SYP
36 sertoli cell tumor 10.2 PGR SYP
37 pulmonary large cell neuroendocrine carcinoma 10.2 CHGA SYP
38 chordoid meningioma 10.2 CHGA SYP
39 petrous apex meningioma 10.2 KANTR PGRMC1
40 radiation cystitis 10.2 F7 KANTR
41 cauda equina neoplasm 10.2 CHGA SYP
42 conventional angiosarcoma 10.2 CHGA SYP
43 foramen magnum meningioma 10.2 KANTR NF2
44 partial motor epilepsy 10.2 F3 SYP
45 abducens nerve disease 10.2 KANTR SYP
46 functional colonic disease 10.2 KANTR SYP
47 intraocular retinoblastoma 10.2 KANTR SYP
48 small cell sarcoma 10.2 NF2 TP53
49 olfactory nerve neoplasm 10.2 CHGA SYP
50 benign ependymoma 10.2 NF2 SYP

Graphical network of the top 20 diseases related to Anterior Cranial Fossa Meningioma:



Diseases related to Anterior Cranial Fossa Meningioma

Symptoms & Phenotypes for Anterior Cranial Fossa Meningioma

UMLS symptoms related to Anterior Cranial Fossa Meningioma:


seizures, headache

GenomeRNAi Phenotypes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 TP53

MGI Mouse Phenotypes related to Anterior Cranial Fossa Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 CHGA F2 F3 F7 PGR PLG
2 mortality/aging MP:0010768 9.91 CHGA F2 F3 F7 NF2 PGR
3 integument MP:0010771 9.8 F2 F3 NF2 PGR PLG TP53
4 nervous system MP:0003631 9.56 CHGA F2 F3 NF2 PGRMC1 PLG
5 neoplasm MP:0002006 9.55 F3 NF2 PGR PLG TP53
6 reproductive system MP:0005389 9.17 CHGA F2 NF2 PGR PGRMC1 PLG

Drugs & Therapeutics for Anterior Cranial Fossa Meningioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Actigraphic Measurement of a Neurosurgical Procedure Completed NCT00945230 Not Applicable

Search NIH Clinical Center for Anterior Cranial Fossa Meningioma

Genetic Tests for Anterior Cranial Fossa Meningioma

Anatomical Context for Anterior Cranial Fossa Meningioma

MalaCards organs/tissues related to Anterior Cranial Fossa Meningioma:

41
Brain, Lung, Colon, Breast, Ovary, Spinal Cord, Cerebellum

Publications for Anterior Cranial Fossa Meningioma

Articles related to Anterior Cranial Fossa Meningioma:

# Title Authors Year
1
The Radiographic Effects of Surgical Approach and Use of Retractors on the Brain After Anterior Cranial Fossa Meningioma Resection. ( 29367000 )
2018
2
Incidental finding of anterior cranial fossa meningioma on 18F-fluoride PET/CT. ( 24096998 )
2013
3
Psychiatric symptoms and an anterior cranial fossa meningioma. ( 9861864 )
1998

Variations for Anterior Cranial Fossa Meningioma

Expression for Anterior Cranial Fossa Meningioma

Search GEO for disease gene expression data for Anterior Cranial Fossa Meningioma.

Pathways for Anterior Cranial Fossa Meningioma

GO Terms for Anterior Cranial Fossa Meningioma

Cellular components related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type peptidase complex GO:1905286 8.62 F3 F7

Biological processes related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of reactive oxygen species metabolic process GO:2000379 9.48 F2 TP53
2 fibrinolysis GO:0042730 9.46 F2 PLG
3 positive regulation of blood coagulation GO:0030194 9.43 F2 F7
4 positive regulation of positive chemotaxis GO:0050927 9.4 F3 F7
5 negative regulation of fibrinolysis GO:0051918 9.37 F2 PLG
6 blood coagulation, extrinsic pathway GO:0007598 9.32 F3 F7
7 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway GO:1900738 9.26 CHGA F2
8 blood coagulation GO:0007596 9.26 F2 F3 F7 PLG
9 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.16 F3 F7
10 hemostasis GO:0007599 8.92 F2 F3 F7 PLG

Molecular functions related to Anterior Cranial Fossa Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 9.16 PGR PGRMC1
2 serine-type peptidase activity GO:0008236 9.13 F2 F7 PLG
3 serine-type endopeptidase activity GO:0004252 8.92 F2 F3 F7 PLG

Sources for Anterior Cranial Fossa Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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