Anterior Scleritis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ANT023 MIFTS: 38	Anterior Scleritis Categories: Eye diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs Download Expand all tables

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Aliases & Classifications for Anterior Scleritis

MalaCards integrated aliases for Anterior Scleritis:

Name: Anterior Scleritis ¹² ¹⁵ ⁷³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:13794

ICD10 ³³ H15.01

ICD9CM ³⁵ 379.03

SNOMED-CT ⁶⁸ 63454000

UMLS ⁷³ C0155353

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Summaries for Anterior Scleritis

MalaCards based summary : Anterior Scleritis is related to loiasis and deep keratitis. An important gene associated with Anterior Scleritis is SRCIN1 (SRC Kinase Signaling Inhibitor 1), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Immune response Fc epsilon RI pathway. The drugs Cyclophosphamide and Infliximab have been mentioned in the context of this disorder. Affiliated tissues include eye, neutrophil and t cells, and related phenotypes are Reduced mammosphere formation and hematopoietic system

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Related Diseases for Anterior Scleritis

Diseases in the Scleritis family:

Posterior Scleritis

Anterior Scleritis

Diseases related to Anterior Scleritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 101)

#	Related Disease	Score	Top Affiliating Genes
1	loiasis	10.9	MFF SRCIN1
2	deep keratitis	10.9	MFF SRCIN1
3	elephantiasis	10.8	MFF SRCIN1
4	plantar fasciitis	10.8	MFF MRAP
5	early yaws	10.7	CD22 CD79A
6	juvenile dermatitis herpetiformis	10.7	CD79A GLS2
7	granuloma inguinale	10.7	CD22 MRAP
8	chondromalacia	10.6	IL1RN TNFRSF1B
9	iritis	10.5	MRAP TNFRSF1B
10	pustulosis of palm and sole	10.5	MRAP TNFRSF1B
11	cow milk allergy	10.5	CD79A IL5
12	tenosynovitis	10.5	MRAP TNFRSF1B
13	scleritis	10.5
14	transient hypogammaglobulinemia of infancy	10.5	CD19 CD79A
15	urethritis	10.5	CD79A MRAP
16	strongyloidiasis	10.5	CD79A IL5
17	bladder lymphoma	10.5	CD19 CD5
18	chorioretinitis	10.5	CD79A MRAP SRCIN1
19	intestinal schistosomiasis	10.4	IL5 SRCIN1
20	congenital hypogammaglobulinemia	10.4	CD19 CD79A
21	autoinflammation, lipodystrophy, and dermatosis syndrome	10.4	IL1RAPL2 IL1RN IL5
22	hypopyon	10.4	MRAP NCAM1
23	cervicitis	10.4	CD79A MRAP
24	b cell prolymphocytic leukemia	10.4	CD19 CD5
25	scleral disease	10.4	MRAP SRCIN1 TNFRSF1B
26	parasitic ichthyosporea infectious disease	10.3	CD79A NCAM1
27	mediastinal cancer	10.3	CD5 NCAM1
28	intravascular large b-cell lymphoma	10.3	B2M CD5
29	rhinosporidiosis	10.3	CD79A NCAM1
30	colon lymphoma	10.3	CD19 CD22 CD5
31	osteosclerotic myeloma	10.3	CD79A IL1RN
32	gastrointestinal allergy	10.3	CD79A IL5
33	conjunctival disease	10.3	CD79A IL5 MRAP
34	exanthem	10.3	CD79A IL1RN TNFRSF1B
35	acute salpingitis	10.2	CD79A MRAP TNFRSF1B
36	orthostatic proteinuria	10.2	B2M CD79A
37	spondyloarthropathy 1	10.2	CD79A MRAP TNFRSF1B
38	anal canal adenocarcinoma	10.2	KRT19 TNFRSF1B
39	plasma protein metabolism disease	10.2	CD19 CD5 CD79A
40	intestinal disease	10.2	CD79A MRAP TNFRSF1B
41	morpheaform basal cell carcinoma	10.2	KRT19 NCAM1
42	norwegian scabies	10.2	CD79A IL5 TNFRSF1B
43	diffuse glomerulonephritis	10.1	B2M CD79A
44	sweat gland disease	10.1	IL1RN TNFRSF1B
45	parasitic helminthiasis infectious disease	10.1	CD79A IL5 MFF SRCIN1
46	danubian endemic familial nephropathy	10.1	B2M CD79A
47	orbital granuloma	10.1	CD79A PRTN3
48	cutaneous adenocystic carcinoma	10.1	B2M KRT19
49	cervix disease	10.0	CD79A MRAP
50	non-secretory myeloma	10.0	B2M CD79A

Graphical network of the top 20 diseases related to Anterior Scleritis:

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Symptoms & Phenotypes for Anterior Scleritis

GenomeRNAi Phenotypes related to Anterior Scleritis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.17	CD22 CD5 CD79A IL5 NCAM1 PRTN3

MGI Mouse Phenotypes related to Anterior Scleritis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	9.81	B2M CD19 CD22 CD5 CD79A IL1RN
2	immune system	MP:0005387	9.61	CD79A IL1RN IL5 PRTN3 TNFRSF1B B2M
3	neoplasm	MP:0002006	9.1	B2M CD19 CD79A IL5 KRT19 TNFRSF1B

Sources

Drugs & Therapeutics for Anterior Scleritis

Drugs for Anterior Scleritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cyclophosphamide

Approved, Investigational

Phase 3

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CPA

CTX

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Ledoxina

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

Infliximab

Approved

Phase 3

170277-31-3

Methotrexate

Approved

Phase 3

1959-05-2, 59-05-2

126941

Synonyms:

4-amino-10-Methylfolate

4-amino-10-methylfolic acid

4-amino-10-Methylfolic acid

4-amino-N(10)-Methylpteroylglutamate

4-amino-N(10)-methylpteroylglutamic acid

4-amino-N(10)-Methylpteroylglutamic acid

Abitrexate

Amethopterin

Amethopterine

Antifolan

Arbitrexate

Dicesium salt methotrexate

Emtexate

Emtexic acid

Folex

HDMTX

Hydrate, methotrexate

L-Amethopterin

Ledertrexate

Ledertrexic acid

Metatrexan

Methopterin

Methotextrate

Methotrate

Methotrexat

Méthotrexate

Methotrexate hydrate

Methotrexate sodium

Methotrexate Sodium

Methotrexate, (D)-isomer

Methotrexate, (DL)-isomer

Methotrexate, dicesium salt

Methotrexate, disodium salt

Methotrexate, sodium salt

Methotrexatum

Methotrexic acid

Methylaminopterin

Methylaminopterinum

Metotrexato

Mexate

MTX

N-[4-[[(2,4-diamino-6-Pteridinyl)methyl]methylamino]benzoyl]-L-glutamate

N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

N-[4-[[(2,4-diamino-6-Pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

N-Bismethylpteroylglutamic acid

N-Bismethylpteroylglutamic Acid

Rheumatrex

Sodium, methotrexate

Trexall

Prednisone

Approved, Vet_approved

Phase 3

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Adasone

AI3-52939

Ancortone

apo-Prednisone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

Anti-Inflammatory Agents

Phase 3,Phase 1

Antineoplastic Agents, Hormonal

Phase 3,Phase 1

Gastrointestinal Agents

Phase 3,Phase 1

glucocorticoids

Phase 3,Phase 1

Hormone Antagonists

Phase 3,Phase 1

Hormones

Phase 3,Phase 1

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 3,Phase 1

Immunosuppressive Agents

Phase 3,Phase 1,Phase 2

Alkylating Agents

Phase 3

Antineoplastic Agents, Alkylating

Phase 3

Antirheumatic Agents

Phase 3

Dermatologic Agents

Phase 3

Everolimus

Approved

Phase 1, Phase 2

159351-69-6

6442177

Synonyms:

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone

(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

001, RAD

07741_FLUKA

159351-69-6

40-O-(2-hydroxyethyl)-rapamycin

40-O-(2-Hydroxyethyl)-rapamycin

42-O-(2-Hydroxyethyl)rapamycin

Afinitor

Certican

CERTICAN(R)

CHEMBL1201755

D02714

DB01590

everolimus

Everolimus

Everolimus (JAN/USAN/INN)

Everolimus [USAN]

LS-143292

MolPort-003-847-342

MolPort-003-925-588

NCGC00167512-01

NVP-RAD-001

RAD 001

RAD, SDZ

RAD001

RAD-001

RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus

RAD-001C

S1120_Selleck

SDZ RAD

SDZ-RAD

UNII-9HW64Q8G6G

Zortress

Miconazole

Approved, Investigational, Vet_approved

Phase 1, Phase 2

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin iv

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (tn)

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Sirolimus

Approved, Investigational

Phase 1, Phase 2

53123-88-9

5284616 6436030 46835353

Synonyms:

(-)-rapamycin

(-)-Rapamycin

1fkb

1pbk

23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine

23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine

23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29

3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone

53123-88-9

A422989, NSC226080

AC1L1JH9

AC1L7MJ9

AC1L9ZMV

AC-722

Ambotz53123-88-9

Antibiotic AY 22989

AY 22989

AY22989

AY-22989

BIDD:PXR0165

Bio1_000293

Bio1_000782

Bio1_001271

Bio2_000375

Bio2_000855

BiomolKI2_000084

C07909

C51H79NO13

CBiol_002007

CCRIS 9024

CHEBI:100923

CHEBI:9168

CHEMBL413

CID10213190

CID10795871

CID11949238

CID11959112

CID313006

CID478951

CID5040

CID5284616

CID5358081

CID5374464

CID5460439

CID5497196

CID5924240

CID6436030

CID6610270

CID6610346

CID6711160

CID6713081

CID9833581

CID9854379

CID9854380

CID9962926

CID9962928

D00753

DB00877

DE-109

DivK1c_006936

FT-0082351

heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy

HMS2089A21

HSDB 7284

KBio1_001880

KBio2_000410

KBio2_002978

KBio2_005546

KBio3_000779

KBio3_000780

KBioGR_000410

KBioSS_000410

LCP-Siro

LMPK06000003

LS-143290

MLS000028373

MolMap_000043

MolPort-003-959-433

MS-R001

NCGC00021305-05

nchembio.100-comp4

nchembio.2007.42-comp2

nchembio.79-comp1

nchembio762-comp1

nchembio883-comp3

NCI60_001851

NCIMech_000355

NSC 226080

NSC226080

Perceiva

QTL1_000069

R0395_SIAL

R0395_SIGMA

RAP

RAPA

Rapammune

Rapamune

Rapamune (TN)

rapamycin

Rapamycin

Rapamycin (TN)

Rapamycin C-7, analog 4

Rapamycin from Streptomyces hygroscopicus

Rapamycin Immunosuppressant Drug

RPM

S1039_Selleck

SIIA 9268A

SILA 9268A

SILA9268A

sirolimus

Sirolimus

sirolimús

Sirolimus (RAPAMUNE)

Sirolimus (USAN/INN)

Sirolimus [USAN:BAN:INN]

Sirolimus, Rapamune,Rapamycin

sirolimusum

SMP1_000255

SMR000058564

SpecPlus_000840

UNII-W36ZG6FT64

UNM-0000358684

Wy 090217

WY-090217

Anti-Bacterial Agents

Phase 1, Phase 2

Antibiotics, Antitubercular

Phase 1, Phase 2

Antifungal Agents

Phase 1, Phase 2

Anti-Infective Agents

Phase 1, Phase 2

Dexamethasone

Approved, Investigational, Vet_approved

Phase 1

50-02-2

5743

Synonyms:

(3H)-Dexamethasone

.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol

.gamma.corten

137098-19-2

16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol

16.alpha.-Methyl-9.alpha.-fluoroprednisolone

16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol

16alpha -Methyl-9alpha -fluoroprednisolone

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol

16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone

16alpha-Methyl-9alpha-fluoroprednisolone

16-alpha-Methyl-9-alpha-fluoroprednisolone

16a-Methyl-9a-fluoro-1-dehydrocortisol

16α-methyl-9α-fluoro-1-dehydrocortisol

16α-Methyl-9α-fluoro-1-dehydrocortisol

1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone

1-dehydro-16alpha -Methyl-9alpha -fluorohydrocortisone

1-dehydro-16alpha-Methyl-9alpha-fluorohydrocortisone

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

1-dehydro-16a-Methyl-9a-fluorohydrocortisone

1-dehydro-16α-methyl-9α-fluorohydrocortisone

1-Dehydro-16α-methyl-9α-fluorohydrocortisone

23495-06-9

31375_FLUKA

46165_FLUKA

46165_RIEDEL

50-02-2

8054-59-9

9.alpha.-Fluoro-16.alpha.-methylprednisolone

906422-84-2

9a-fluoro-16a-Methylprednisolone

9a-fluoro-16BETA-METHYLPREDNISOLONE

9A-FLUORO-16BETA-METHYLPREDNISOLONE

9alpha -fluoro-16alpha -Methylprednisolone

9alpha-fluoro-16alpha-Methylprednisolone

9alpha-fluoro-16alpha-Methyl-prednisolone

9-alpha-fluoro-16-alpha-Methylprednisolone

9alpha-Fluoro-16alpha-methylprednisolone

9-alpha-Fluoro-16-alpha-methylprednisolone

9-fluoro-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione

9-fluoro-11alpha -Methylpregna-1,4-diene-3,20-dione

9-fluoro-16-Methylprednisolone

9α-fluoro-16α-methylprednisolone

9α-Fluoro-16α-methylprednisolone

AC-11056

AC1L1L1H

AC1Q29DM

Adexone

Aeroseb-D

Aeroseb-dex

Aeroseb-Dex

AI3-50934

Ak dex OPH otic soln 0.1%

Alcon brand OF dexamethasone

Alcon Brand of Dexamethasone

alpha -fluoro-16-alpha -Methylcortisol

Anaflogistico

Aphtasolon

Aphthasolone

apo-Dexamethasone

Auxiron

Azimycin (veterinary)

Azium

Azium (veterinary)

Azium (Veterinary)

BIDD:ER0494

BIDD:PXR0060

Bisu Ds

Bisu DS

BRD-K38775274-001-02-3

BRD-K38775274-001-06-4

BSPBio_000995

C15643

C22H29FO5

Calonat

CCRIS 7067

CHEBI:41879

CHEMBL384467

CID5743

Corson

Corsone

Cortisumman

CPD001227192

CPD-10549

D00292

D003907

D1756_SIGMA

D4902_SIGMA

D6645_SIGMA

D8893_SIGMA

D9184_SIGMA

DB01234

Decacort

Decacortin

Decaderm

Decadron

Decadron (TN)

Decadron Tablets, Elixir

Decadron, Dexamethasone

Decadron-La

Decadron-LA

Decagel

Decaject

Decaject l.a.

Decaject L.A.

Decaject-l.a.

Decaject-L.A.

Decalix

Decameth

Decasone

Decaspray

Dectancyl

Dekacort

delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol

delta1-9alpha-Fluoro-16alpha-methylcortisol

Delta1-9alpha-fluoro-16alpha-Methylcortisol

Deltafluorene

Dergramin

Deronil

Desadrene

Desametasone

Desametasone [Dcit]

Desametasone [DCIT]

Desamethasone

Desameton

Deseronil

DEX

Dexa

DEXA

Dexa mamallet

Dexa Mamallet

Dexacen-4

Dexacidin

Dexacort

Dexacortal

Dexa-cortidelt

Dexa-Cortidelt

Dexacortin

Dexa-cortisyl

Dexa-Cortisyl

Dexadeltone

Dexafarma

Dexair

Dexalona

Dexaltin

Dexa-Mamallet

Dexametasona

Dexametasona [INN-Spanish]

Dexametasone

Dexameth

Dexamethansone

dexamethasone

Dexamethasone

Dexamethasone (JP15/USP/INN)

Dexamethasone [INN:BAN:JAN]

Dexamethasone acetate

Dexamethasone Acetate

Dexamethasone alcohol

Dexamethasone Alcohol

Dexamethasone base

Dexamethasone Base

Dexamethasone intensol

Dexamethasone Intensol

Dexamethasone sodium phosphate

Dexamethasone Sodium Phosphate

Dexamethasone-omega

Dexamethasonum

Dexamethasonum [INN-Latin]

Dexamethazone

Dexamonozon

Dexapolcort

Dexapos

Dexaprol

Dexa-scheroson

Dexa-Scheroson

Dexa-sine

Dexa-Sine

Dexason

Dexasone

Dexasone 0.5MG

Dexasone 0.75MG

Dexasone 4MG

Dexasporin

Dex-ide

Dex-Ide

Dexinolon

Dexinoral

Dexone

Dexone 0.5

DEXONE 0.5

Dexone 0.75

DEXONE 0.75

Dexone 1.5

DEXONE 1.5

Dexone 4

DEXONE 4

Dexonium

Dexpak

Dextelan

Dezone

Dinormon

DXM

Dxms

DXMS

ECR brand OF dexamethasone

ECR Brand of Dexamethasone

EINECS 200-003-9

Fluormethylprednisolone

Fluormone

Fluorocort

Fortecortin

Foy brand OF dexamethasone

Foy Brand of Dexamethasone

FT-0080377

Gammacorten

Hexadecadrol

Hexadrol

Hexadrol elixir

Hexadrol Elixir

Hexadrol Tablets

Hl-dex

Hl-Dex

HL-Dex

HMS1792A17

HMS1990A17

HMS2089N13

HSDB 3053

I06-1196

ICN brand OF dexamethasone

ICN Brand of Dexamethasone

IontoDex

isopto-Dex

Isopto-Dex

Lokalison F

Loverine

LS-7300

Luxazone

Maxidex

Maxidex ont 0.1%

Maxidex sus 0.1%

Maxitrol

Mediamethasone

Merck brand OF dexamethasone

Merck Brand of Dexamethasone

Merz brand 1 OF dexamethasone

Merz Brand 1 of Dexamethasone

Merz brand 2 OF dexamethasone

Merz Brand 2 of Dexamethasone

Methylfluorprednisolone

Mexidex

Millicorten

MK 125

MLS001055412

MLS001332507

MLS001332508

MolMap_000018

MolPort-003-846-433

Mymethasone

Naquasone (veterinary)

NCGC00091019-01

NCGC00091019-02

NCGC00091019-03

NCGC00091019-04

NCGC00091019-05

nchembio809-comp2

NCI60_003067

Neomycin and polymyxin b sulfates and dexamethasone

Neomycin and polymyxin b sulphates and dexamethasone

NSC 34521

NSC34521

Ocu-trol

Ocu-Trol

Oradexon

OTO-104

Pet derm III

Pet Derm Iii

Pet Derm III

Pet-Derm Iii

PHL-Dexamethasone

PMS Dexamethasone elixir 0.5mg/5ML

PMS-Dexamethasone

Policort

Posurdex

Prednisolon F

Prednisolone F

Prodex

S1322_Selleck

SAM002548948

Sandoz dexamethasone

SGCUT00126

Sk-Dexamethasone

SK-Dexamethasone

SMP1_000092

SMR000857119

SMR001227192

Spectrum5_002019

Spoloven

ST50307091

Sunia sol D

Sunia Sol D

Superprednol

TL8003317

to_000038

Tobradex

Tobramycin and dexamethasone

Tresaderm (veterinary)

Turbinaire

UNII-7S5I7G3JQL

Visumetazone

WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1

ZINC03875332

Antiemetics

Phase 1

Autonomic Agents

Phase 1

BB 1101

Phase 1

Dexamethasone 21-phosphate

Phase 1

Dexamethasone acetate

Phase 1

1177-87-3

HIV Protease Inhibitors

Phase 1

Ophthalmic Solutions

Phase 1

Peripheral Nervous System Agents

Phase 1

Pharmaceutical Solutions

Phase 1

protease inhibitors

Phase 1

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS)	Not yet recruiting	NCT03088293	Phase 3	Infliximab;Cyclophosphamide
2	Sirolimus Injections for Autoimmune Scleritis	Completed	NCT01517074	Phase 1, Phase 2	Sirolimus
3	Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study	Completed	NCT01059955	Phase 1	Dexamethasone Phosphate Ophthalmic Solution (EGP-437);Dexamethasone phosphate ophthalmic solution
4	Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis	Completed	NCT01958567	Not Applicable

Search NIH Clinical Center for Anterior Scleritis

Sources

Genetic Tests for Anterior Scleritis

Sources

Anatomical Context for Anterior Scleritis

MalaCards organs/tissues related to Anterior Scleritis:

⁴¹

Eye, Neutrophil, T Cells, Breast, Lung

Sources

Publications for Anterior Scleritis

Articles related to Anterior Scleritis:

(show all 47)

#	Title	Authors	Year
1	Iontophoretic delivery of dexamethasone phosphate for non-infectious, non-necrotising anterior scleritis, dose-finding clinical trial. ( 29666122 )	O'Neil E.C....Kempen J.H.	2018
2	Limbal Stem Cell Deficiency Secondary to Diffuse Non-necrotizing Anterior Scleritis: A Clinicopathological Report. ( 29794824 )	Khoo L.W....Roberts F.	2018
3	Ocular metastasis from breast carcinoma simulating anterior scleritis: a case report. ( 28844204 )	Shah R.K....Lamichhane S.	2017
4	Anterior scleritis following intravitreal injections in a patient with rheumatoid arthritis: A case report. ( 29382031 )	Ryu S.J....Shin Y.U.	2017
5	Indocyanine green angiography in anterior scleritis. ( 28886929 )	Garcia-Saenz M.C....BaA+uelos BaA+uelos J.	2017
6	Anterior Scleritis Associated with Pemphigus Vulgaris. ( 29095065 )	Zeeli T....Sprecher E.	2017
7	Uveitis Specialists and Rheumatologists Select Different Therapies for Idiopathic Non-necrotizing Anterior Scleritis. ( 27744531 )	Ozzello D.J....Palestine A.G.	2016
8	Gevokizumab in the treatment of autoimmune, non-necrotizing, anterior scleritis: Results of a phase I/II clinical trial. ( 27663070 )	Knickelbein J.E....Sen H.N.	2016
9	Subconjunctival sirolimus in the treatment of autoimmune non-necrotizing anterior scleritis: results of a phase I/II clinical trial. ( 25526946 )	Bhatt N....Sen H.N.	2015
10	Anterior segment spectral domain optical coherence tomography imaging of patients with anterior scleritis. ( 26597942 )	Levison A.L....Srivastava S.K.	2015
11	Flurbiprofen: A Nonselective Cyclooxygenase (COX) Inhibitor for Treatment of Noninfectious, Non-necrotizing Anterior Scleritis. ( 26308394 )	Agrawal R....Pavesio C.	2015
12	Adalimumab-induced remission of anterior scleritis: a very rare late manifestation of Takayasu arteritis. ( 26320134 )	Akhtar S....Mason J.C.	2015
13	Cotrimoxazole as a Treatment for Recurrent Idiopathic Anterior Scleritis: A Single-center Experience in 20 Patients. ( 24432898 )	Bielefeld P....Bron A.M.	2014
14	Diffuse anterior scleritis and secondary glaucoma as a manifestation of adult T-cell prolymphocytic leukemia. ( 24977988 )	Kommaraju K.R....Demirci H.	2014
15	Anterior scleritis and celiac disease: a proposed association. ( 23876049 )	Keller J....Sainz de la Maza M.	2013
16	Management and outcome of microbial anterior scleritis. ( 21694595 )	Cunningham M.A....Wilhemus K.R.	2011
17	Resolution of anterior scleritis after periodontal therapy. ( 21769277 )	Guncu G.N....Caglayan F.	2011
18	Long-term, multicenter evaluation of subconjunctival injection of triamcinolone for non-necrotizing, noninfectious anterior scleritis. ( 21708408 )	Sohn E.H....Rao N.	2011
19	Subconjunctival triamcinolone acetonide injection in the treatment of acute noninfectious nonnecrotizing anterior scleritis. ( 20510689 )	Onal S....Kazokoglu H.	2010
20	Subconjunctival triamcinolone treatment for non-necrotising anterior scleritis. ( 20447959 )	Roufas A....McCluskey P.	2010
21	Trabeculectomy with mitomycin C in refractory glaucoma associated with nonnecrotizing anterior scleritis. ( 20001263 )	Williams T.A....Shah P.	2009
22	Anterior scleritis as the presenting sign of metastatic lung cancer. ( 18156383 )	Taban M....Singh A.D.	2008
23	Optic atrophy, necrotizing anterior scleritis and keratitis presenting in association with Streptococcal Toxic Shock Syndrome: a case report. ( 18312659 )	Papageorgiou K.I....Sinha A.J.	2008
24	Necrotising anterior scleritis in a late-onset rheumatoid arthritis (LORA) patient. ( 17365805 )	Ooi K.G....Adler P.A.	2007
25	Nodular non-necrotising anterior scleritis due to Nocardia nova infection. ( 16878113 )	Das S....Whiting M.	2007
26	Efficacy of the IL-1 receptor antagonist, anakinra, for the treatment of diffuse anterior scleritis in rheumatoid arthritis. Report of two cases. ( 17449489 )	Botsios C....Punzi L.	2007
27	Fungal endophthalmitis complicating subconjunctival injection of triamcinolone acetonide in anterior scleritis. ( 17416964 )	Singh R....Gupta A.	2006
28	Anterior scleritis, scleral thinning, and intraocular pressure measurement. ( 16321890 )	Nessim M....Murray P.I.	2005
29	Celecoxib, a selective inhibitor of cyclooxygenase 2 for therapy of diffuse anterior scleritis. ( 15953441 )	Bauer A.M....Becker M.D.	2005
30	Subconjunctival corticosteroid injection for the treatment of non-necrotising anterior scleritis. ( 15965178 )	Sen H.N....Buggage R.R.	2005
31	Successful treatment of refractory anterior scleritis in primary Sjogren's syndrome with rituximab. ( 15958765 )	Ahmadi-Simab K....Gross W.L.	2005
32	Evaluation of subconjunctival triamcinolone for nonnecrotizing anterior scleritis. ( 16199269 )	Albini T.A....Rao N.A.	2005
33	Therapeutic decision in anterior scleritis: our experience at a tertiary care eye center. ( 16395198 )	Carrasco M.A....Laibson P.R.	2005
34	The diagnosis and management of anterior scleritis. ( 15791166 )	Albini T.A....Smith R.E.	2005
35	Acute febrile neutrophilic dermatosis (Sweet's syndrome) with erythema nodosum and anterior scleritis. A case report. ( 16409276 )	Mazokopakis E....Papadakis J.A.	2005
36	Anterior scleritis: three case reports and a review of the literature. ( 15296376 )	Castells D.D.	2004
37	Bilateral centripetal lipid keratopathy with diffuse anterior scleritis. ( 12752066 )	Morisawa M....Tsuru T.	2003
38	Anterior segment indocyanine green angiography in anterior scleritis and episcleritis. ( 13129874 )	Guex-Crosier Y....Durig J.	2003
39	Self-inflicted anterior scleritis. ( 12579186 )	Mushtaq B....Murray P.I.	2003
40	A prospective evaluation of subconjunctival injection of triamcinolone acetonide for resistant anterior scleritis. ( 11927443 )	Zamir E....Rao N.A.	2002
41	Nodular anterior scleritis associated with ocular trauma. ( 11465321 )	Smith J.R....Chee S.P.	2001
42	Self-inflicted anterior scleritis. ( 11150288 )	Zamir E....Rao N.A.	2001
43	Subconjunctival corticosteroid injections for nonnecrotizing anterior scleritis. ( 10408466 )	Croasdale C.R....Brightbill F.S.	1999
44	Use of topical steroid therapy in the management of nonnecrotizing anterior scleritis. ( 10396658 )	McMullen M....Hodge W.G.	1999
45	Therapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection. ( 7777270 )	Tu E.Y....Chodosh J.C.	1995
46	Necrotising anterior scleritis after pterygium surgery. ( 7818874 )	Galanopoulos A....O'Day J.	1994
47	Diffuse anterior scleritis during OKT3 monoclonal antibody therapy for renal transplant rejection. ( 1555131 )	McCarthy J.M....Rollins D.T.	1992

Sources

Genes for Anterior Scleritis

Genes related to Anterior Scleritis (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SRCIN1	SRC Kinase Signaling Inhibitor 1	Protein Coding	16.8	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	KRT12	Keratin 12	Protein Coding	15.73	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	MFF	Mitochondrial Fission Factor	Protein Coding	15.64	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	GLS2	Glutaminase 2	Protein Coding	14.07	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	CD22	CD22 Molecule	Protein Coding	13.94	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	IL1RN	Interleukin 1 Receptor Antagonist	Protein Coding	13.81	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	CD5	CD5 Molecule	Protein Coding	13.33	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	MRAP	Melanocortin 2 Receptor Accessory Protein	Protein Coding	13.31	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	CD79A	CD79a Molecule	Protein Coding	13.29	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	IL5	Interleukin 5	Protein Coding	13.27	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	13.14	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	CD19	CD19 Molecule	Protein Coding	13.13	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	13.12	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
14	B2M	Beta-2-Microglobulin	Protein Coding	13.06	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
15	IL1RAPL2	Interleukin 1 Receptor Accessory Protein Like 2	Protein Coding	7.09	GeneCards inferred via : Publications (show sections)
16	PRTN3	Proteinase 3	Protein Coding	5.02	DISEASES inferred ¹⁵
17	KRT19	Keratin 19	Protein Coding	3.53	DISEASES inferred ¹⁵

Sources

Variations for Anterior Scleritis

Sources

Expression for Anterior Scleritis

Search GEO for disease gene expression data for Anterior Scleritis.

Sources

Pathways for Anterior Scleritis

Pathways related to Anterior Scleritis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.02	B2M IL1RN IL5 NCAM1 PRTN3 TNFRSF1B
2	Immune response Fc epsilon RI pathway ²² Show member pathways Fc epsilon RI signaling pathway ³⁷ Fc-epsilon receptor I signaling in mast cells ¹ Immune response BCR pathway ²² VEGF signaling pathway ³⁷	12.2	CD19 CD22 CD79A IL5
3	NF-kappaB Signaling ⁴	11.95	B2M CD19 CD79A IL1RN NCAM1 TNFRSF1B
4	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell ⁶⁶	11.71	B2M CD19 CD22
5	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers ⁶⁶ Show member pathways B-Cell Receptor Complex ⁶⁴ CD22 mediated BCR regulation ⁶⁶ CLEC7A (Dectin-1) induces NFAT activation ⁶⁶ FCERI mediated Ca+2 mobilization ⁶⁶	11.52	CD19 CD22 CD79A
6	Hematopoietic cell lineage ³⁷	11.44	CD19 CD22 CD5 IL5
7	B Cell Development Pathways ⁶⁵	11.16	CD19 CD22 CD5
8	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.16	CD19 CD22 CD5 CD79A IL5 NCAM1

Sources

GO Terms for Anterior Scleritis

Cellular components related to Anterior Scleritis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	9.44	B2M CD19 CD22 CD5 CD79A IL1RAPL2
2	external side of plasma membrane	GO:0009897	9.35	B2M CD19 CD5 CD79A NCAM1

Biological processes related to Anterior Scleritis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine-mediated signaling pathway	GO:0019221	9.02	IL1RAPL2 IL1RN IL5 PRTN3 TNFRSF1B

Molecular functions related to Anterior Scleritis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:0005515	9.53	B2M CD19 CD22 CD5 CD79A GLS2

Sources

Sources for Anterior Scleritis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

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¹⁰ dbSNP

¹¹ DGIdb

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¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

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⁴⁸ NCBI Bookshelf

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⁵² NIH Clinical Center

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⁵⁵ Novoseek

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⁵⁷ OMIM

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⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

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⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia