MCID: ANT013
MIFTS: 29

Anterior Spinal Artery Syndrome

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Anterior Spinal Artery Syndrome

MalaCards integrated aliases for Anterior Spinal Artery Syndrome:

Name: Anterior Spinal Artery Syndrome 12 43 15 17 71
Anterior Spinal Artery Occlusion Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6712
MeSH 43 D020759
SNOMED-CT 67 282785008
ICD10 32 G83.82
UMLS 71 C0221069

Summaries for Anterior Spinal Artery Syndrome

MalaCards based summary : Anterior Spinal Artery Syndrome, also known as anterior spinal artery occlusion syndrome, is related to paraplegia and spinal cord infarction. An important gene associated with Anterior Spinal Artery Syndrome is SRP72 (Signal Recognition Particle 72), and among its related pathways/superpathways is Platelet activation. The drugs Lidocaine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, liver and eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 74 Anterior spinal artery syndrome (also known as "anterior spinal cord syndrome") is syndrome caused by... more...

Related Diseases for Anterior Spinal Artery Syndrome

Diseases related to Anterior Spinal Artery Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 paraplegia 10.5
2 spinal cord infarction 10.4
3 aortic aneurysm 10.2
4 spinal cord injury 10.2
5 aortic dissection 10.2
6 back pain 10.2
7 pain agnosia 10.1
8 arteriosclerosis 10.1
9 aneurysm 10.1
10 aortic aneurysm, familial abdominal, 1 10.0
11 coarctation of aorta 10.0
12 systemic lupus erythematosus 10.0
13 spondylosis, cervical 10.0
14 scoliosis 10.0
15 idiopathic scoliosis 10.0
16 endocarditis 10.0
17 arteriovenous malformation 10.0
18 quadriplegia 10.0
19 spondylosis 10.0
20 protein s deficiency 10.0
21 hemangioma 10.0
22 vascular myelopathy 10.0
23 myelitis 10.0
24 lupus erythematosus 10.0
25 spastic paraparesis 10.0
26 spasticity 10.0
27 hypercholesterolemia, familial, 1 9.9
28 marfan syndrome 9.9
29 scoliosis, isolated 1 9.9
30 down syndrome 9.9
31 hydrops fetalis, nonimmune 9.9
32 pulmonary disease, chronic obstructive 9.9
33 aortic aneurysm, familial thoracic 1 9.9
34 hypertensive nephropathy 9.9
35 ewing sarcoma 9.9
36 peripheral vascular disease 9.9
37 rheumatic heart disease 9.9
38 infective endocarditis 9.9
39 pulmonary edema 9.9
40 horner's syndrome 9.9
41 neurogenic bladder 9.9
42 detrusor sphincter dyssynergia 9.9
43 spinal muscular atrophy 9.9
44 subclavian steal syndrome 9.9
45 coccidioidomycosis 9.9
46 patent foramen ovale 9.9
47 hypothyroidism 9.9
48 thrombocytopenia 9.9
49 vascular disease 9.9
50 thrombocytosis 9.9

Graphical network of the top 20 diseases related to Anterior Spinal Artery Syndrome:



Diseases related to Anterior Spinal Artery Syndrome

Symptoms & Phenotypes for Anterior Spinal Artery Syndrome

GenomeRNAi Phenotypes related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

26 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-104 9.5 NCBP1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.5 GABRR3
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.5 GABRR3
4 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.5 NCBP1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.5 GABRR3
6 Increased shRNA abundance (Z-score > 2) GR00366-A-153 9.5 NCBP1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.5 NCBP1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.5 NCBP1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.5 GABRR3
10 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.5 NCBP1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.5 NCBP1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-6 9.5 NCBP1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.5 NCBP1 PPP1R12A
14 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.5 NCBP1

Drugs & Therapeutics for Anterior Spinal Artery Syndrome

Drugs for Anterior Spinal Artery Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved 137-58-6 3676
2
Epinephrine Approved, Vet_approved 51-43-4 5816
3
Iodine Approved, Investigational 7553-56-2 807
4
Racepinephrine Approved 329-65-7 838
5
Povidone Approved 9003-39-8
6
Povidone-iodine Approved 25655-41-8
7
Bupivacaine Approved, Investigational 2180-92-9, 38396-39-3 2474
8 Tea
9 Pharmaceutical Solutions
10 Epinephryl borate
11 cadexomer iodine

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation the Effect of Ultrasound Guided Superficial, Deep Serratus Plane Blocks and Thoracic Epidural in Cancer Patients Undergoing Thoracotomy: A Prospective Randomized Controlled Study Recruiting NCT04189120

Search NIH Clinical Center for Anterior Spinal Artery Syndrome

Cochrane evidence based reviews: anterior spinal artery syndrome

Genetic Tests for Anterior Spinal Artery Syndrome

Anatomical Context for Anterior Spinal Artery Syndrome

MalaCards organs/tissues related to Anterior Spinal Artery Syndrome:

40
Spinal Cord, Liver, Eye, Brain, Colon, Prostate

Publications for Anterior Spinal Artery Syndrome

Articles related to Anterior Spinal Artery Syndrome:

(show top 50) (show all 204)
# Title Authors PMID Year
1
Anterior spinal artery syndrome caused by thoracic disc herniation. 61
32409217 2020
2
Anterior Spinal Artery Syndrome: A Rare Precedented Reason of Postoperative Plegia After Spinal Deformity Surgery: A Report of Two Cases. 61
32502625 2020
3
A case report of atopic myelitis mimicking anterior spinal artery syndrome. 61
31713189 2020
4
Fibrocartilaginous embolism as a cause of anterior spinal artery syndrome? 61
32238974 2020
5
Lund University Cardiac Assist System Induced Liver Laceration and Anterior Cord Infarction After Cardiac Arrest: A Case Report. 61
31842196 2020
6
Anterior Spinal Artery Syndrome in a Patient with Cervical Spondylosis Demonstrated by CT Angiography. 61
31680448 2019
7
Acute Anterior Spinal Artery Syndrome in the Context of Multisystem Arterial Emboli. 61
31544725 2019
8
Anterior spinal artery syndrome and aortic dissection. 61
31264980 2019
9
Management of the left subclavian artery during TEVAR - complications and mid-term follow-up. 61
29788799 2018
10
Anterior spinal artery syndrome from type A aortic dissection in a patient with Marfan syndrome due to a novel fibrillin mutation. 61
29992200 2018
11
A case with angiographic demonstration of isolated anterior spinal artery occlusion. 61
29889472 2018
12
Cocaine-Related Acute Spinal Cord Infarction. 61
29393308 2018
13
Transient paraplegia after neurolytic splanchnic block in a patient with metastatic colon carcinoma. 61
29372026 2018
14
A Case of Anterior Spinal Artery Syndrome Caused by Streptococcus mitis Endocarditis. 61
29560019 2018
15
Acute tetraplegia following laryngotracheal reconstruction surgery. 61
29416908 2018
16
The Cervical Arteries: An Anatomical Study with Application to Avoid the Nerve Root and Spinal Cord Blood Supply. 61
28266004 2018
17
Anterior spinal artery syndrome after double valve replacement and coronary artery bypass surgery. 61
28469882 2017
18
Coronary angiography as a rare cause for incomplete anterior spinal artery syndrome. 61
28229242 2017
19
Anterior Spinal Artery Syndrome Following Coronary Artery Bypass Grafting: a Case Report. 61
28492795 2017
20
"Man in the Barrel" Syndrome with Anterior Spinal Artery Infarct due to Vertebral Artery Dissection. 61
28065615 2017
21
Delayed Hospital Presentation and Neuroimaging in Non-surgical Spinal Cord Infarction. 61
28446898 2017
22
Anterior spinal artery syndrome after spinal anaesthesia for caesarean delivery with normal lumbar and thoracic magnetic resonance imaging. 61
27184089 2016
23
Etiological, clinical, and radiological features of longitudinally extensive myelopathy in Chinese patients. 61
27526974 2016
24
Poster 431 Anterior Spinal Artery Syndrome Caused by Traumatic Disk Herniation: A Case Report. 61
27673181 2016
25
Cervical disc herniation as a trigger for temporary cervical cord ischemia. 61
27683710 2016
26
Systemic thrombolysis in anterior spinal artery syndrome: what has to be considered? 61
26386968 2016
27
A Clinical Perspective and Definition of Spinal Cord Injury. 61
27015067 2016
28
Guillain Barré Syndrome, Systemic Lupus Erythematosus and Acute Intermittent Porphyria – A Deadly Trio. 61
29900713 2015
29
"Owl eye sign": Anterior spinal artery syndrome. 61
26053834 2015
30
Persistent paralysis after spinal anesthesia for cesarean delivery. 61
25433726 2015
31
Mechanisms and prevention of anterior spinal artery syndrome following abdominal aortic surgery. 61
25757179 2015
32
[Longitudinally extensive spinal cord lesion: etiology and imaging features]. 61
25604223 2014
33
The prevalence of abnormal preoperative neurological examination in Scheuermann kyphosis: correlation with X-ray, magnetic resonance imaging, and surgical outcome. 61
25029218 2014
34
Thoracic disc herniation leads to anterior spinal artery syndrome demonstrated by diffusion-weighted magnetic resonance imaging (DWI): a case report and literature review. 61
24252234 2014
35
[Cervical medullar infarction in multileveled discopathy]. 61
24908948 2014
36
Anterior spinal artery syndrome in a patient with vasospasm secondary to a ruptured cervical dural arteriovenous fistula. 61
22211300 2014
37
Anterior spinal artery syndrome: reversible paraplegia after minimally invasive spine surgery. 61
25210639 2014
38
[Acute non-traumatic myelopathy in children and adolescents]. 61
23897140 2013
39
Anterior spinal artery syndrome presenting as cervical myelopathy in a patient with subclavian steal syndrome. 61
24195022 2013
40
Images in anesthesiology: reversible anterior spinal artery syndrome during celiac plexus block. 61
22710956 2013
41
Subacute anterior spinal cord ischemia with lower limb monoplegia: a clinical dilemma and challenging scenario. 61
22983543 2012
42
Delayed onset of anterior spinal artery syndrome after repair of aortic coarctation. 61
22858787 2012
43
Thrombolysis in anterior spinal artery syndrome. 61
22962400 2012
44
Spinal Cord Infarction Caused by Non-dissected and Unruptured Thoracoabdominal Aortic Aneurysm with Intraluminal Thrombus. 61
22639759 2012
45
A case of spontaneous spinal epidural hematoma mimicking a stroke. 61
22217615 2012
46
Spinal cord syndromes. 61
22377894 2012
47
Painless transient paraparesis as the solitary manifestation of aortic dissection. 61
21741795 2011
48
[A case of benign postpartum anterior spinal artery syndrome with thrombocytosis and high fibrolytic activity]. 61
21987569 2011
49
[Two cases of posterior spinal artery syndrome (PSAS)]. 61
21946428 2011
50
Anterior spinal artery syndrome after percutaneous vertebroplasty. 61
21835701 2011

Variations for Anterior Spinal Artery Syndrome

Expression for Anterior Spinal Artery Syndrome

Search GEO for disease gene expression data for Anterior Spinal Artery Syndrome.

Pathways for Anterior Spinal Artery Syndrome

Pathways related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.72 PPP1R12A F2

GO Terms for Anterior Spinal Artery Syndrome

Biological processes related to Anterior Spinal Artery Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell growth GO:0030307 8.62 NCBP1 F2

Sources for Anterior Spinal Artery Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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