MCID: ANT014
MIFTS: 13

Anterior Urethra Cancer

Categories: Cancer diseases

Aliases & Classifications for Anterior Urethra Cancer

MalaCards integrated aliases for Anterior Urethra Cancer:

Name: Anterior Urethra Cancer 12
Anterior Urethral Malignant Tumor 12
Anterior Urethral Cancer 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8272
NCIt 49 C7641
UMLS 71 C0279930

Summaries for Anterior Urethra Cancer

Disease Ontology : 12 A female urethral cancer located in the anterior urethra.

MalaCards based summary : Anterior Urethra Cancer, is also known as anterior urethral malignant tumor. The drugs Gemcitabine and leucovorin have been mentioned in the context of this disorder. Affiliated tissues include anterior urethra, kidney and liver.

Related Diseases for Anterior Urethra Cancer

Diseases in the Urethra Cancer family:

Posterior Urethra Cancer Anterior Urethra Cancer

Symptoms & Phenotypes for Anterior Urethra Cancer

Drugs & Therapeutics for Anterior Urethra Cancer

Drugs for Anterior Urethra Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Gemcitabine Approved Phase 2, Phase 3 95058-81-4 60750
2
leucovorin Approved Phase 2, Phase 3 58-05-9 6006 143
3
Cisplatin Approved Phase 2, Phase 3 15663-27-1 2767 441203 84093
4
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
5
Methotrexate Approved Phase 2, Phase 3 59-05-2, 1959-05-2 126941
6
Vinblastine Approved Phase 2, Phase 3 865-21-4 241903 13342
7
Carboplatin Approved Phase 3 41575-94-4 10339178 38904 498142
8
Folic acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
9 Anti-Infective Agents Phase 2, Phase 3
10 Antiviral Agents Phase 2, Phase 3
11 Immunologic Factors Phase 2, Phase 3
12 Vitamin B Complex Phase 2, Phase 3
13 Folate Phase 2, Phase 3
14 Immunosuppressive Agents Phase 2, Phase 3
15 Vitamin B9 Phase 2, Phase 3
16 Antimetabolites Phase 2, Phase 3
17 Folic Acid Antagonists Phase 2, Phase 3
18 Albumin-Bound Paclitaxel Phase 3
19 Tubulin Modulators Phase 2, Phase 3
20 Antimitotic Agents Phase 2, Phase 3
21 Dermatologic Agents Phase 2, Phase 3
22 Antirheumatic Agents Phase 2, Phase 3
23
Sunitinib Approved, Investigational Phase 2 557795-19-4, 341031-54-7 5329102
24
Ifosfamide Approved Phase 2 3778-73-2 3690
25
Gefitinib Approved, Investigational Phase 2 184475-35-2 123631
26
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
27
Pemetrexed Approved, Investigational Phase 2 137281-23-3, 150399-23-8 60843 446556
28
Fluorouracil Approved Phase 2 51-21-8 3385
29
Levoleucovorin Approved, Investigational Phase 2 68538-85-2
30
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
31
Lonafarnib Investigational Phase 2 193275-84-2 148195
32
Rubitecan Investigational Phase 2 91421-42-0
33
Camptothecin Experimental Phase 2 7689-03-4
34 Protein Kinase Inhibitors Phase 2
35 Angiogenesis Inhibitors Phase 2
36 Alkylating Agents Phase 2
37
Isophosphamide mustard Phase 2 0
38 topoisomerase I inhibitors Phase 2
39 Vitamins Phase 2
40 Micronutrients Phase 2
41 Antidotes Phase 2
42 Nutrients Phase 2
43 Trace Elements Phase 2
44 Protective Agents Phase 2
45
Docetaxel Approved, Investigational Phase 1 114977-28-5 148124
46
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
47
Entinostat Investigational Phase 1 209783-80-2
48 Interferon alpha-2 Phase 1
49 interferons Phase 1
50 Interferon-alpha Phase 1

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 Phase III Trial of Methotrexate, Vinblastine, Doxorubicin and Cisplatin vs Carboplatin and Paclitaxel in Advanced Carcinoma of the Urothelium Completed NCT00003376 Phase 3 carboplatin;cisplatin;doxorubicin hydrochloride;methotrexate;paclitaxel;vinblastine
2 Randomized Phase II/III Study Assessing Gemcitabine/Carboplatin And Methotrexate/Carboplatin/Vinblastine In Previously Untreated Patients With Advanced Urothelial Cancer Ineligible For Cisplatin Based Chemotherapy Completed NCT00014274 Phase 2, Phase 3 carboplatin;gemcitabine hydrochloride;methotrexate;vinblastine sulfate
3 Multicenter Study of the Quality of Life of Patients With Invasive Urothelial Cancer Treated With Conservative Surgery Followed by Cisplatin, Fluorouracil and Radiotherapy Unknown status NCT00006111 Phase 2 cisplatin;fluorouracil
4 Phase II Study of Sunitinib in Metastatic Transitional Cell Carcinoma of the Urothelium Completed NCT00397488 Phase 2 sunitinib malate
5 Phase II Trial of Neoadjuvant, Multi-Agent Chemotherapy For Locally Advanced Urothelial Cancer Completed NCT00080795 Phase 2 cisplatin;doxorubicin hydrochloride;gemcitabine hydrochloride;ifosfamide
6 Phase II Study on SCH 66336 (Farnesyl Protein Transferase Inhibitor) and Gemcitabine as Second Line Treatment in Advanced Metastatic Urothelial Cancer - EORTC Study 16997 Completed NCT00006351 Phase 2 gemcitabine hydrochloride;lonafarnib
7 Open Label Phase II Study on RFS 2000 (9-Nitro-Camptothecin, 9-NC) Administered as a "5 Days On-2 Days Off" Oral Treatment in Advanced/Metastatic Urothelial Tract Tumors Completed NCT00006026 Phase 2 rubitecan
8 Evaluation of ZD1839 (NSC #715055) for Advanced Transitional Cell Carcinoma of the Urothelium, Phase II Completed NCT00014144 Phase 2 gefitinib
9 Phase II Study of Irinotecan in Patients With Advanced Transitional Cell Carcinoma of the Urothelium Completed NCT00066612 Phase 2 irinotecan hydrochloride
10 Phase II Trial Of Pemetrexed Disodium And Gemcitabine In Advanced Urothelial Cancer Completed NCT00053209 Phase 2 gemcitabine hydrochloride;pemetrexed disodium
11 A Phase II Single-Arm Trial to Evaluate Cisplatin and Gemcitabine Chemotherapy in Combination With Sunitinib for First-Line Treatment of Patients With Advanced Transitional Carcinoma of the Urothelium Completed NCT01089088 Phase 2 cisplatin;gemcitabine hydrochloride;sunitinib malate
12 A Sequential Approach to the Treatment of Muscle Invasive, Non-Metastatic Urothelial Carcinoma of the Bladder: A Phase II Trial of Neoadjuvant Gemcitabine, Paclitaxel and Carboplatin With Molecular Correlates Completed NCT00045630 Phase 2 carboplatin;gemcitabine;paclitaxel
13 A Randomized Phase II Trial of Carboplatin and Gemcitabine +/- Vandetanib in First Line Treatment of Advanced Urothelial Cell Cancer in Patients Who Are Not Suitable to Receive Cisplatin Completed NCT01191892 Phase 2 carboplatin;gemcitabine hydrochloride;vandetanib;Placebo
14 Phase II Trial of 5-FU, Leucovorin, Gemcitabine, and Cisplatin for Adenocarcinomas of the Urothelial Tract and Urachal Remnant Active, not recruiting NCT00082706 Phase 2 5-Fluorouracil (5-FU);Leucovorin;Cisplatin;Gemcitabine
15 A Phase II Study of Depsipeptide (NSC-630176) In Patients With Advanced Transitional Cell Carcinoma Of The Urinary Tract Who Have Progressed After Receiving One Prior Chemotherapy Regimen For Advanced Disease Terminated NCT00087295 Phase 2 Depsipeptide
16 Protocol for Assessment of Gemcitabine and Paclitaxel for Metastatic Urothelial Cancer in Patients Aged 70 Years or Older (and in a Cohort of Patients Younger Than 60 Years) Terminated NCT00022633 Phase 2 gemcitabine hydrochloride;paclitaxel
17 Randomized Phase II Trial Of Adjuvant Chemotherapy For Urothelial Carcinoma Comparing GC To Dose-Dense MVAC Withdrawn NCT01639521 Phase 2 cisplatin;gemcitabine hydrochloride;methotrexate;vinblastine;doxorubicin hydrochloride
18 Modulation of Death Effector Expression By Short-Term Exposure to Low-Dose Interferon Completed NCT00082719 Phase 1
19 Phase I Pharmacokinetic Trial of Thalidomide and Docetaxel: A Regimen Based on Anti-Angiogenic Therapeutic Principles Completed NCT00049296 Phase 1 docetaxel;thalidomide
20 A Phase I Study of an Oral Histone Deacetylase Inhibitor, MS-275, in Refractory Solid Tumors and Lymphomas Completed NCT00020579 Phase 1 entinostat
21 BARC: A Secreted Marker of Kidney Cancer Completed NCT00900276
22 Improving Palliative Care for Patients With Cancer Completed NCT00253383

Search NIH Clinical Center for Anterior Urethra Cancer

Genetic Tests for Anterior Urethra Cancer

Anatomical Context for Anterior Urethra Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Anterior Urethra Cancer:

19
Anterior Urethra

MalaCards organs/tissues related to Anterior Urethra Cancer:

40
Kidney, Liver

Publications for Anterior Urethra Cancer

Variations for Anterior Urethra Cancer

Expression for Anterior Urethra Cancer

Search GEO for disease gene expression data for Anterior Urethra Cancer.

Pathways for Anterior Urethra Cancer

GO Terms for Anterior Urethra Cancer

Sources for Anterior Urethra Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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