MCID: ANT014
MIFTS: 13

Anterior Urethra Cancer

Categories: Cancer diseases

Aliases & Classifications for Anterior Urethra Cancer

MalaCards integrated aliases for Anterior Urethra Cancer:

Name: Anterior Urethra Cancer 12
Anterior Urethral Malignant Tumor 12
Anterior Urethral Cancer 73

Classifications:



External Ids:

Disease Ontology 12 DOID:8272
NCIt 50 C7641
UMLS 73 C0279930

Summaries for Anterior Urethra Cancer

MalaCards based summary : Anterior Urethra Cancer, is also known as anterior urethral malignant tumor. The drugs Gemcitabine and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include liver and kidney.

Related Diseases for Anterior Urethra Cancer

Symptoms & Phenotypes for Anterior Urethra Cancer

Drugs & Therapeutics for Anterior Urethra Cancer

Drugs for Anterior Urethra Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Gemcitabine Approved Phase 2, Phase 3 95058-81-4 60750
2
Cisplatin Approved Phase 3,Phase 2 15663-27-1 84093 441203 2767
3
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 498142 38904
4
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
5
Vinblastine Approved Phase 3,Phase 2 865-21-4 13342 241903
6
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
7
Paclitaxel Approved, Vet_approved Phase 3,Phase 2 33069-62-4 36314
8
leucovorin Approved, Nutraceutical Phase 3,Phase 2 58-05-9 143 6006
9
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
10
Doxil Approved June 1999 Phase 3,Phase 2 31703
11 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
12 Anti-Infective Agents Phase 2, Phase 3,Phase 1
13 Antimetabolites Phase 3,Phase 2
14 Antiviral Agents Phase 2, Phase 3,Phase 1
15 Antimetabolites, Antineoplastic Phase 3,Phase 2
16 Folic Acid Antagonists Phase 3,Phase 2
17 Albumin-Bound Paclitaxel Phase 3,Phase 2
18 Topoisomerase Inhibitors Phase 3,Phase 2
19 Dermatologic Agents Phase 3,Phase 2
20 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
21 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
22 Vitamin B Complex Phase 3,Phase 2
23 Antibiotics, Antitubercular Phase 3,Phase 2
24 Antirheumatic Agents Phase 3,Phase 2
25 Antimitotic Agents Phase 3,Phase 2,Phase 1
26 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
27 Folate Nutraceutical Phase 3,Phase 2
28 Vitamin B9 Nutraceutical Phase 3,Phase 2
29
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
30
Fluorouracil Approved Phase 2 51-21-8 3385
31
Lenograstim Approved, Investigational Phase 2 135968-09-1
32
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
33
Ifosfamide Approved Phase 2 3778-73-2 3690
34
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
35
Gefitinib Approved, Investigational Phase 2 184475-35-2 123631
36
Pemetrexed Approved, Investigational Phase 2 150399-23-8, 137281-23-3 446556 60843
37
Levoleucovorin Approved, Investigational Phase 2 68538-85-2
38
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
39
Camptothecin Experimental Phase 2 7689-03-4
40
Rubitecan Investigational Phase 2 91421-42-0
41 Angiogenesis Inhibitors Phase 2,Phase 1
42 Angiogenesis Modulating Agents Phase 2,Phase 1
43
Isophosphamide mustard Phase 2 0
44 Alkylating Agents Phase 2
45 topoisomerase I inhibitors Phase 2
46 Protein Kinase Inhibitors Phase 2
47 Antineoplastic Agents, Alkylating Phase 2
48
Docetaxel Approved, Investigational Phase 1 114977-28-5 148124
49
Entinostat Investigational Phase 1 209783-80-2
50 interferons Phase 1

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium Completed NCT00003376 Phase 3 carboplatin;cisplatin;doxorubicin hydrochloride;methotrexate;paclitaxel;vinblastine
2 Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium Completed NCT00014274 Phase 2, Phase 3 carboplatin;gemcitabine hydrochloride;methotrexate;vinblastine sulfate
3 Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer Unknown status NCT01191892 Phase 2 carboplatin;gemcitabine hydrochloride;vandetanib;Placebo
4 Gemcitabine Hydrochloride, Cisplatin, and Sunitinib Malate as First-Line Therapy in Treating Patients With Locally Advanced And/or Metastatic Transitional Cell Carcinoma of the Urothelium Unknown status NCT01089088 Phase 2 cisplatin;gemcitabine hydrochloride;sunitinib malate
5 Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract Unknown status NCT00006111 Phase 2 cisplatin;fluorouracil
6 Neoadjuvant Ifosfamide, Doxorubicin, Gemcitabine, and Cisplatin in Treating Patients Who Are Undergoing Radical Cystectomy for Locally Advanced Carcinoma (Cancer) of the Urothelium Completed NCT00080795 Phase 2 cisplatin;doxorubicin hydrochloride;gemcitabine hydrochloride;ifosfamide
7 S0219, Combination Chemotherapy Followed By Observation or Surgery in Patients With Stage II or Stage III Cancer of the Urothelium Completed NCT00045630 Phase 2 carboplatin;gemcitabine;paclitaxel
8 Sunitinib in Treating Patients With Progressive Metastatic Transitional Cell Cancer of the Urothelium Completed NCT00397488 Phase 2 sunitinib malate
9 SCH 66336 Plus Gemcitabine in Treating Patients With Advanced Cancer of the Urinary Tract Completed NCT00006351 Phase 2 gemcitabine hydrochloride;lonafarnib
10 Nitrocamptothecin in Treating Patients With Metastatic Cancer of the Urinary Tract Completed NCT00006026 Phase 2 rubitecan
11 S0031, ZD 1839 in Treating Patients With Advanced Cancer of the Urinary Tract Completed NCT00014144 Phase 2 gefitinib
12 S0306, Irinotecan in Treating Patients With Recurrent or Refractory Advanced Transitional Cell Cancer of the Urothelium Previously Treated With Chemotherapy Completed NCT00066612 Phase 2 irinotecan hydrochloride
13 Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium Completed NCT00053209 Phase 2 gemcitabine hydrochloride;pemetrexed disodium
14 Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant Active, not recruiting NCT00082706 Phase 2 5-Fluorouracil (5-FU);Leucovorin;Cisplatin;Gemcitabine
15 S0400, FR901228 in Treating Patients With Advanced Cancer of the Urothelium Terminated NCT00087295 Phase 2 Depsipeptide
16 S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract Terminated NCT00022633 Phase 2 gemcitabine hydrochloride;paclitaxel
17 Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer Withdrawn NCT01639521 Phase 2 cisplatin;gemcitabine hydrochloride;methotrexate;vinblastine;doxorubicin hydrochloride
18 Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium Completed NCT00082719 Phase 1
19 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
20 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
21 Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants Completed NCT00900276
22 Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients Completed NCT00253383 Not Applicable

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Genetic Tests for Anterior Urethra Cancer

Anatomical Context for Anterior Urethra Cancer

MalaCards organs/tissues related to Anterior Urethra Cancer:

41
Liver, Kidney

Publications for Anterior Urethra Cancer

Variations for Anterior Urethra Cancer

Expression for Anterior Urethra Cancer

Search GEO for disease gene expression data for Anterior Urethra Cancer.

Pathways for Anterior Urethra Cancer

GO Terms for Anterior Urethra Cancer

Sources for Anterior Urethra Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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