Anterior Urethral Valve disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Orphanet: ⁵⁸ A rare, congenital, fetal lower urinary tract obstruction (LUTO) anomaly occurring in males and characterized by a posteriorly directed semilunar fold arising from the floor of the anterior urethra and causing urethral obstruction during micturition. The valves may be located anywhere distal to the membranous urethra. Clinical presentation is highly variable, depending on age and degree of urinary obstruction, and includes urinary incontinence, urinary retention, weak urinary stream, post-micturitional dribbling, bulging on the ventral penis, urinary tract infection, and urosepsis.

MalaCards based summary: Anterior Urethral Valve is related to posterior urethral valves and urinary tract obstruction.

Sources

Related Diseases for Anterior Urethral Valve

Diseases in the Anterior Urethral Valve family:

Posterior Urethral Valves

Diseases related to Anterior Urethral Valve via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)

#	Related Disease	Score
1	posterior urethral valves	10.5
2	urinary tract obstruction	10.4
3	urethral stricture	10.3
4	urethral diverticulum	10.3
5	urinary tract infection	10.2
6	bladder neck obstruction	10.2
7	hydronephrosis	10.1
8	neurogenic bladder	10.1
9	urinary tract infections, recurrent	10.0
10	hypospadias	10.0
11	pyelonephritis	10.0
12	balanitis	10.0
13	balanitis xerotica obliterans	10.0
14	acute pyelonephritis	10.0
15	end stage renal disease	10.0
16	chronic kidney disease	10.0
17	vesicoureteral reflux	10.0

Graphical network of the top 20 diseases related to Anterior Urethral Valve:

Sources

Symptoms & Phenotypes for Anterior Urethral Valve

Sources

Drugs & Therapeutics for Anterior Urethral Valve

Search Clinical Trials, NIH Clinical Center for Anterior Urethral Valve

Sources

Genetic Tests for Anterior Urethral Valve

Sources

Anatomical Context for Anterior Urethral Valve

Sources

Publications for Anterior Urethral Valve

Articles related to Anterior Urethral Valve:

(show all 50)

#	Title	Authors	PMID	Year
1	Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves. ⁶²	Menon P...Rao KLN	36123286	2022
2	Anterior urethral valve associated with balanitis xerotica obliterans: A rare case report. ⁶²	Li M	36031515	2022
3	Concomitant anterior urethral valve, distal urethral diverticulum and posterior urethral valve with five-year follow up; A case report and literature review. ⁶²	Ganjaroudi NM...Kajbafzadeh AM	35311025	2022
4	Case Report: Neonatal Urinary Ascites Without Hydronephrosis: A Rare Case of Anterior Urethral Valve and Diverticulum in Preterm Newborn. ⁶²	He Y...Zhang R	35844749	2022
5	Are anterior urethral valve and anterior urethral diverticulum two separate entities: A radiological and endoscopic review. ⁶²	Jain P...Jain S	33229229	2021
6	Anterior Urethral Valve - A Commonly Misdiagnosed Entity in Adolescent Boys. ⁶²	Reddy D...Shekar P A	32087211	2020
7	A Rare Association of Posterior Urethral Valve with Anterior Urethral Valve, Large Anterior Urethral Diverticula, and Glanular Hypospadias. ⁶²	Jain P...Jain S	33457674	2020
8	Prenatal diagnosis and postnatal outcome of anterior urethral anomalies. ⁶²	Perlman S...Gilboa Y	31654578	2020
9	Long-term renal outcome in infants with congenital lower urinary tract obstruction. ⁶²	Berte N...Lemelle JL	29980359	2018
10	Anterior Urethral Valve: Uncommon Association with Renal Duplicity. ⁶²	Salem AB...Hafsa C	28770138	2017
11	Male urethral diverticulum uncommon entity: Our experience. ⁶²	Thakur N...Mullay A	28057997	2016
12	Anterior Urethral Valve: A Rare But an Important Cause of Infravesical Urinary Tract Obstruction. ⁶²	Parmar JP...Vora MP	27231492	2016
13	Concomitant anterior and posterior urethral valves in pediatrics: A single center experience over 12 years and long-term follow up after endoscopic treatment. ⁶²	Kajbafzadeh AM...Mehdizadeh M	25689730	2015
14	Re: Tran et al.: anterior urethral valve associated with posterior urethral valves: report of 2 cases and review of the literature (Urology 2014;84:469-471). ⁶²	Keihani S...Kajbafzadeh AM	25733298	2015
15	Anterior urethral valve associated with posterior urethral valves: report of 2 cases and review of the literature. ⁶²	Tran CN...Rhee A	24958476	2014
16	Sepsis in a newborn with anterior urethral valve and urinary tract infection. ⁶²	Liu X...Wu D	24438643	2014
17	Congenital anterior urethral valve with or without diverticulum: a single-centre experience. ⁶²	Prakash J...Singh BP	23764376	2013
18	A case of hypospadias, anterior and posterior urethral valves. ⁶²	Carvell J...Mulik R	24964414	2013
19	Anterior urethral valves: not such a benign condition…. ⁶²	Cruz-Diaz O...Castellan MA	24400281	2013
20	Anterior urethral valve and diverticulum in a neonate with febrile urinary tract infection. ⁶²	Song JH...Kim DS	22866225	2012
21	Missed diagnosis of anterior urethral valve complicated with a foreign body: a cause for concern. ⁶²	Nayyar R...Gupta NP	21478596	2011
22	Megacystis with an anterior urethral valve: case report and review of literature. ⁶²	Confer SD...Kropp BP	20837325	2010
23	Case report: prenatal intervention for severe anterior urethral valve. ⁶²	Mizuno Y...Igarashi T	20500471	2010
24	Anterior urethral valve in the fossa navicularis presenting as a split urinary stream in a child. ⁶²	Kubota Y...Takahashi Y	18323174	2008
25	Anterior urethral valve--an [corrected] uncommon cause of urethral obstruction. ⁶²	Hassam SM...Tew K	17991067	2007
26	Anterior urethral valve in an adolescent with nocturnal enuresis. ⁶²	Wu CC...Tsai YC	18068473	2007
27	Neonatal abdominal wall urinoma due to rupture of anterior urethral diverticulum. ⁶²	Obara W...Fujioka T	16734857	2006
28	Holmium laser ablation of anterior urethral valves: case report. ⁶²	Al-Busaidy SS...Pai SV	16359217	2005
29	Anterior urethral valve associated with posterior urethral valves. ⁶²	Kajbafzadeh AM...Ahmadi Yazdi C	18947585	2005
30	Congenital urethral anomalies in boys. Part II. ⁶²	Kajbafzadeh A	17602414	2005
31	Fetal bladder rupture due to anteriorurethral valves. ⁶²	Merrot T...Alessandrini P	12809917	2003
32	Ultrasound diagnosis of the anterior urethral valve. ⁶²	Bates DG...Coley BD	11512003	2001
33	Anterior urethral valve as a cause of end-stage renal disease. ⁶²	Aygun C...Ozkardes H	11260343	2001
34	Diagnosis of the congenital urethral anomalies of male child by voiding cystourethrography. ⁶²	Lo WC...Lim KE	10910605	1999
35	[Cutaneous vesicostomy in children]. ⁶²	Tucci S...Martins AC	14685401	1997
36	Anterior urethral valve in an adolescent boy. ⁶²	Punekar SV...Prem AR	10707710	1995
37	[Endoscopic operation of congenital anterior urethral valve. Application of flexible renoureteroscope for antegrade urethroscopy]. ⁶²	Kawasaki T...Sato S	1434276	1992
38	Application of flexible renoureteroscope for antegrade urethroscopy in the treatment of congenital anterior urethral valve. ⁶²	Takeda M...Sato S	1468473	1992
39	[Congenital lower urinary tract obstruction and enuresis in children]. ⁶²	Mori Y...Ikoma F	2072610	1991
40	Urethral abnormalities in male neonates with VATER association. ⁶²	Fernbach SK	1898547	1991
41	Anterior urethral valve presenting in an adult male. ⁶²	Khim A...Raffel J	2042270	1991
42	Anterior urethral valve. ⁶²	Ono Y...Mitsuya H	7147535	1982
43	[Anterior urethral valve in a newborn infant]. ⁶²	Halal F...Laberge I	519616	1979
44	[Anterior urethral valve in a five year old boy (author's transl)]. ⁶²	Grasset D...Guiter J	1003609	1976
45	Anterior urethral valve: complications and treatment. ⁶²	Blumberg N...Maletta TJ	5052262	1972
46	Anterior urethral valve as cause for urinary obstruction: a case report. ⁶²	Texter JH...Engel RM	5061464	1972
47	Congenital anterior urethral valve--diagnosis and treatment. ⁶²	Daniel J...Blair DW	5683574	1968
48	ANTERIOR URETHRAL VALVE: A CASE REPORT. ⁶²	COLABAWALLA BN	14319473	1965
49	Anterior urethral valve: a rare cause of bilateral hydronephrosis. ⁶²	WATERHOUSE K...SCORDAMAGLIA LJ	14005223	1962
50	Diagnosis of anterior urethral valve by voiding urethrography: report of two cases. ⁶²	HOPE JW...MICHIE AJ	14403021	1960

Sources

Genes for Anterior Urethral Valve

Sources

Variations for Anterior Urethral Valve

Sources

Expression for Anterior Urethral Valve

Search GEO for disease gene expression data for Anterior Urethral Valve.

Sources

Pathways for Anterior Urethral Valve

Sources

GO Terms for Anterior Urethral Valve

Sources

Sources for Anterior Urethral Valve

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: ANT062 MIFTS: 14	Anterior Urethral Valve Categories: Fetal diseases, Nephrological diseases, Rare diseases, Respiratory diseases	Data Licensing For inquiries, contact: [email protected]
Related diseases Publications Expand all tables