MCID: ANT018
MIFTS: 51

Anthracosis

Categories: Rare diseases, Respiratory diseases
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Aliases & Classifications for Anthracosis

MalaCards integrated aliases for Anthracosis:

Name: Anthracosis 11 43 14 16 71 75 33
Black Lung 11 2 33
Coal Workers' Pneumoconiosis 11 75
Black Lung Disease 19 33
Pneumoconiosis 19 71
Melanoedema 11 33
Fibrosis of Lung with Anthracosilicosis 33
Cwp - [coalworkers Pneumoconiosis] 33
Lung Fibrosis with Anthracosis 33
Coal Worker's Pneumoconiosis 19
Coal Miner's Pneumoconiosis 11
Coal Workers Pneumoconiosis 53
Coal Miners' Pneumoconiosis 33
Miners' Pneumoconiosis 33
Colliers' Anthracosis 33
Coal Pneumoconiosis 33
Coal Workers' Lung 11
Anthracosilicosis 33
Coal Miners' Lung 33
Collier's Asthma 33
Lung Anthracosis 33
Pneumomelanosis 33
Coalworker Lung 33
Colliers' Lung 33
Lung Melanosis 33
Miners' Asthma 33
Miners' Lung 33
Carbon Lung 33

Classifications:



External Ids:

Disease Ontology 11 DOID:10327
ICD9CM 34 500
MeSH 43 D055008
NCIt 49 C34390
SNOMED-CT 68 29422001
ICD10 31 J60
ICD11 33 1355167773
UMLS 71 C0003165 C0032273

Summaries for Anthracosis

CDC: 2 The pneumoconioses are a group of interstitial lung diseases caused by the inhalation of certain dusts and the lung tissue's reaction to the dust. The principal cause of the pneumoconioses is work-place exposure; environmental exposures have rarely given rise to these diseases. The primary pneumoconioses are asbestosis, silicosis, and coal workers' pneumoconiosis (commonly referred to as CWP or black lung). As their names imply, they are caused by inhalation of asbestos fibers, silica dust, and coal mine dust. Typically, these three diseases take many years to develop and be manifested, although in some cases – silicosis, particularly – rapidly progressive forms can occur after only short periods of intense exposure. When severe, the diseases often lead to lung impairment, disability, and premature death. From a public health perspective, these conditions are entirely man-made, and can be avoided through appropriate dust control. Other forms of pneumoconioses can be caused by inhaling dusts containing aluminum, antimony, barium, graphite, iron, kaolin, mica, talc, among other dusts. There is also a form called mixed-dust pneumoconiosis. Overall, most physicians do not encounter these diseases very frequently. Byssinosis, caused by exposure to cotton dust, is sometimes included among the pneumoconioses, although its pattern of lung abnormality is different from the pneumoconioses listed here.

MalaCards based summary: Anthracosis, also known as black lung, is related to baritosis and bronchitis. An important gene associated with Anthracosis is CCL2 (C-C Motif Chemokine Ligand 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Pirfenidone and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include lung, lymph node and heart, and related phenotype is Synthetic lethal with MLN4924 (a NAE inhibitor).

GARD: 19 A diffuse parenchymal lung disease caused by inhalation of dust and by tissue reaction to their presence. These inorganic, organic, particulate, or vaporized matters usually are inhaled by workers in their occupational environment, leading to the various forms (ASBESTOSIS; BYSSINOSIS; and others). Similar air pollution can also have deleterious effects on the general population.

Disease Ontology: 11 A pneumoconiosis that is characterized by deposition of carbon or coal dust in the lung parenchyma leading to the formation of black nodules and emphysema.

Wikipedia: 75 Coal workers' pneumoconiosis (CWP), also known as black lung disease or black lung, is an occupational... more...

Related Diseases for Anthracosis

Diseases related to Anthracosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 712)
# Related Disease Score Top Affiliating Genes
1 baritosis 32.0 CXCL8 CCL2
2 bronchitis 30.9 TNF IL6 IL1B CXCL8
3 pulmonary tuberculosis 30.6 TNF IL6 IL1B CCL2
4 extrinsic allergic alveolitis 30.5 TNF MUC5B CXCL8 CCL2
5 aspergillosis 30.3 TNF IL6 IL1B CXCL8
6 pulmonary sarcoidosis 30.3 TNF IL6 CCL2
7 lymphadenitis 30.2 TNF IL6 IL1B CXCL8
8 silicosis 30.2 TNF NLRP3 IL1B CXCL8 CCL2
9 pulmonary alveolar proteinosis 30.1 TNF IL6 CXCL8 CCL2
10 arteries, anomalies of 30.0 TNF IL6 IL1B CCL2
11 pleural tuberculosis 30.0 TNF CXCL8 CCL2
12 peripheral vascular disease 30.0 TNF IL6 IL1B CCL2
13 pneumoconiosis 30.0 TNF SOD1 IL6 IL1B CXCL8 CCL2
14 autoimmune disease 29.9 TNF IL6 IL1B CCL2 BMP6
15 systemic scleroderma 29.9 TNF IL6 IL1B CXCL8 CCL2
16 persistent fetal circulation syndrome 29.9 TNF IL6 IL1B
17 pleural disease 29.9 TNF IL6 IL1B CXCL8
18 sarcoidosis 1 29.9 TNF IL6 IL1B CCL2
19 rheumatic heart disease 29.8 TNF IL6 IL1B
20 pulmonary edema 29.8 TNF IL1B CXCL8
21 pneumonia 29.8 TNF MUC5B IL6 IL1B CXCL8 CCL2
22 mycobacterium kansasii 29.8 NLRP3 CXCL8
23 pleurisy 29.8 TNF IL1B CXCL8 CCL2
24 endocarditis 29.8 TNF IL6 CXCL8
25 peptic ulcer disease 29.7 TNF IL6 IL1B CXCL8
26 haemophilus influenzae 29.7 TNF IL1B CXCL8
27 speech and communication disorders 29.7 TNF PRODH IL6 IL1B
28 leptin deficiency or dysfunction 29.7 TNF IL6 IL1B CCL2
29 respiratory failure 29.7 TNF SOD1 NLRP3 IL6 IL1B CXCL8
30 bronchiolitis obliterans 29.7 TNF IL6 CXCL8
31 common cold 29.7 TNF IL6 IL1B CXCL8
32 bronchiectasis 29.6 TNF IL6 IL1B CXCL8
33 vascular disease 29.6 TNF SOD1 IL6 CCL2 BMP6
34 rhinitis 29.6 TNF IL6 IL1B CXCL8
35 bronchiolitis 29.6 TNF IL6 IL1B CXCL8 CCL2
36 interstitial lung disease 2 29.6 TNF NLRP3 MUC5B IL6 IL1B CXCL8
37 atherosclerosis susceptibility 29.6 TNF IL6 IL1B CXCL8 CCL2
38 interstitial lung disease 29.5 TNF MUC5B IL6 IL1B CXCL8 CCL2
39 esophagitis 29.5 TNF IL6 IL1B CXCL8
40 cellulitis 29.5 TNF IL6 IL1B CXCL8
41 paranasal sinus disease 29.5 TNF IL6 IL1B CXCL8
42 pericarditis 29.5 TNF IL6 IL1B CXCL8
43 pulmonary disease, chronic obstructive 29.5 TNF IL6 IL1B CXCL8 CCL2
44 pulmonary fibrosis 29.5 MUC5B IL1B CXCL8 CCL2 BMP6
45 lipoprotein quantitative trait locus 29.4 TNF NLRP3 IL6 IL1B CXCL8 CCL2
46 bronchopneumonia 29.4 TNF IL6 IL1B CXCL8 CCL2
47 myelodysplastic syndrome 29.4 TNF IL6 IL1B CXCL8 BMP6
48 bronchial disease 29.3 TNF MUC5B IL6 IL1B CXCL8 CCL2
49 anxiety 29.3 TNF PRODH IL6 IL1B CXCL8
50 gout 29.3 TNF NLRP3 IL6 IL1B CXCL8

Comorbidity relations with Anthracosis via Phenotypic Disease Network (PDN): (show all 12)


Bronchitis Chronic Pulmonary Heart Disease
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Intermediate Coronary Syndrome
Pneumoconiosis Postinflammatory Pulmonary Fibrosis
Prostate Cancer Prostatic Hypertrophy
Respiratory Failure Silicosis

Graphical network of the top 20 diseases related to Anthracosis:



Diseases related to Anthracosis

Symptoms & Phenotypes for Anthracosis

GenomeRNAi Phenotypes related to Anthracosis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.44 CARD8 CXCL8 IL1B NLRP3 SOD1 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.44 CARD8 CXCL8 IL1B NLRP3 SOD1 TMEM268

Drugs & Therapeutics for Anthracosis

Drugs for Anthracosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pirfenidone Approved, Investigational Phase 3 53179-13-8 40632
2 Analgesics Phase 3
3 Antirheumatic Agents Phase 3
4 Anti-Inflammatory Agents, Non-Steroidal Phase 3
5 Analgesics, Non-Narcotic Phase 3
6 Anti-Inflammatory Agents Phase 3
7
Nintedanib Approved Phase 2 656247-17-5 135423438 9809715
8 Protein Kinase Inhibitors Phase 2
9
Cocaine Approved, Illicit 50-36-2 446220 5760
10 Radiopharmaceuticals Early Phase 1
11 FAPI-46 Early Phase 1

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 A Randomized, Double-blind, Placebo-controlled, Multicenter Phase III Clinical Trial of Efficacy and Safety of Pirfenidone Capsules in the Treatment of Pneumoconiosis Not yet recruiting NCT05288179 Phase 3 Pirfenidone Capsules;placebo capsules
2 The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial Recruiting NCT04161014 Phase 2 Nintedanib 150 MG [Ofev]
3 Examination of Pirfenidone (Esbriet®) Therapy in Coal Workers' Pneumoconiosis With Pulmonary Fibrosis Associated With Radiographic and Functional Impairment to Examine the Reduction in Progression of Disease, Reduction of Exacerbation Rates and Possible Reduction of Inflammatory Biomarkers as an Index of Clinical Response. Active, not recruiting NCT04461587 Phase 2 Pirfenidone
4 A Phase I Study of Human Umbilical Cord-Mesenchymal Stem Cells for Pneumoconiosis Unknown status NCT02790762 Phase 1
5 A Multicenter, Randomized, Single-blind, Parallel-group Study of Combined Large Volume WLL With Clinical Grade Umbilical Cord Mesenchymal Stem Cells(MSC) Transplantation for Treatment of Pneumoconiosis Completed NCT02668068 Phase 1
6 Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma Unknown status NCT04205708
7 The Experience of Patients and Family Caregivers in Managing Pneumoconiosis in the Family Context: An Exploratory Qualitative Study Completed NCT04022902
8 Investigate the Potential of Deep Learning in Assessing Pneumoconiosis Depicted on Digital Chest Radiographs and to Compare Its Performance With Certified Radiologists Completed NCT04963348
9 Specialized Center of Research in Occupational and Immunologic Lung Disease Completed NCT00005280
10 Effects of Chinese Medicine on Patients With Coal Worker's Pneumoconiosis: Study Protocol for a Randomized Controlled Trial Recruiting NCT04841200 Chinese medicine compound combined with symptomatic treatments;Chinese medicine compound placebo combined with symptomatic treatments
11 The Development and Clinical Application of Pneumoconiosis High Risk Early Warning Models Based on Convolutional Neural Network in Chest Radiography Recruiting NCT04952675
12 PET Study of 68Ga-FAPi-46 in Patients With Interstitial Lung Disease: an Exploratory Biodistribution Study With Histopathology Validation. Recruiting NCT05365802 Early Phase 1 68Ga-FAPi-46

Search NIH Clinical Center for Anthracosis

Cochrane evidence based reviews: anthracosis

Genetic Tests for Anthracosis

Anatomical Context for Anthracosis

Organs/tissues related to Anthracosis:

MalaCards : Lung, Lymph Node, Heart, Liver, Neutrophil, Monocytes, Bone Marrow

Publications for Anthracosis

Articles related to Anthracosis:

(show top 50) (show all 4975)
# Title Authors PMID Year
1
[Transforming growth factor beta and tumor necrosis factor gene polymorphism and coal worker's pneumoconiosis]. 53 62
19493496 2009
2
Polymorphisms in chemokine and chemokine receptor genes and the development of coal workers' pneumoconiosis. 53 62
16524739 2006
3
[Oxidative injury and serum cytokines in coal workers with pneumoconiosis]. 53 62
16078574 2005
4
MCP-1 secretion in lung from nonsmoking patients with coal worker's pneumoconiosis. 53 62
9072984 1997
5
The role of cytokines in human lung fibrosis. 53 62
8680382 1996
6
Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor beta and relationship to disease severity. 53 62
7921435 1994
7
Co-occurrence of pneumoconiosis with COPD, pneumonia and lung cancer. 62
35932472 2022
8
Postexposure progression of pneumoconiosis among former Appalachian coal miners. 62
36161659 2022
9
Prevalence of coal worker's pneumoconiosis: a systematic review and meta-analysis. 62
35836046 2022
10
Serum metabolic profiling of coal worker's pneumoconiosis using untargeted lipidomics. 62
35796929 2022
11
Welder's lung and brain MRI findings in manganese-exposed welders. 62
36475507 2022
12
Giant Cell Interstitial Pneumonia In Native, Transplanted And Re-Transplanted Lungs 8 Years Apart Without Known Hard Metal Exposure. 62
35382615 2022
13
Progressive massive fibrosis: An overview of the recent literature. 62
35732247 2022
14
Efficacy of direct oral anticoagulant for renal infarction due to pulmonary vein stump thrombosis after left pneumonectomy. 62
36459304 2022
15
Calibration of low-cost particulate matter sensors for coal dust monitoring. 62
36414053 2022
16
Radiological Findings in the Case Exposed to Zirconium. 62
36101981 2022
17
How much have adverse occupational health outcomes among construction workers improved over time? Evidence from 25 years of medical screening. 62
36398410 2022
18
Challenges in the Implementation of the Rajasthan Pneumoconiosis Policy. 62
36081326 2022
19
High-resolution computed tomography diagnosis of pneumoconiosis complicated with pulmonary tuberculosis based on cascading deep supervision U-Net. 62
36179657 2022
20
Prognostic Implication of Exfoliative Airway Pathology in Cancer-Free Coal Workers' Pneumoconiosis. 62
36429692 2022
21
Comparison of ARIMA model, DNN model and LSTM model in predicting disease burden of occupational pneumoconiosis in Tianjin, China. 62
36434563 2022
22
Characteristics and factors associated with morbidity of migrant workers with pneumoconiosis: a cross-sectional study. 62
36368744 2022
23
Proportions distribution of pneumoconiosis stages in China: a study based on a meta-analysis and field investigation. 62
36285421 2022
24
[Investigation on dust pollution and pneumoconiosis incidence in a steel enterprise]. 62
36348553 2022
25
Charcoal maker's pneumoconiosis. 62
36176719 2022
26
Inter-observer agreement and accuracy in classifying radiographs for pneumoconiosis among Asian physicians taking AIR Pneumo certification examination. 62
34803130 2022
27
Differentiation and prediction of pneumoconiosis stage by computed tomography texture analysis based on U-Net neural network. 62
36057227 2022
28
A Fully Deep Learning Paradigm for Pneumoconiosis Staging on Chest Radiographs. 62
35834466 2022
29
Clinical efficacy of comprehensive therapy based on traditional Chinese medicine patterns on patients with pneumoconiosis: a pilot double-blind, randomized, and placebo-controlled study. 62
35451681 2022
30
Nonmalignant respiratory disease mortality in male Colorado Plateau uranium miners, 1960-2016. 62
35941829 2022
31
Risk of Mortality from Respiratory Malignant and Non-Malignant Diseases among Talc Miners and Millers: A Systematic Review and Meta-Analysis. 62
36287869 2022
32
Assessment of Risk of Rheumatoid Arthritis Among Underground Hard Rock and Other Mining Industry Workers in Colorado, New Mexico, and Utah. 62
36251293 2022
33
FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis. 62
36087468 2022
34
[Analysis on disease burden and trend of occupational lung disease in Tianjin from 2010 to 2019 based on disability adjusted life years]. 62
36348559 2022
35
Epidemiology of silicosis reported to the central register of occupational diseases over last 20 years in Poland. 62
35678162 2022
36
Study on dust-gas coupling pollution law and selection of optimal purification distance of air duct during tunneling process. 62
35643998 2022
37
Human neutrophil peptide 1 promotes immune sterilization in vivo by reducing the virulence of multidrug-resistant Klebsiella pneumoniae and increasing the ability of macrophages. 62
34664729 2022
38
Understanding the pathogenesis of occupational coal and silica dust-associated lung disease. 62
35831008 2022
39
Progressive Massive Fibrosis Mimicking Lung Cancer: Two Case Reports with Potentially Useful CT Features for Differential Diagnosis. 62
36276214 2022
40
Oridonin attenuates lung inflammation and fibrosis in silicosis via covalent targeting iNOS. 62
36076611 2022
41
A 44-year-old stone worker with progressive dyspnea: lessons from a new twist on an old foe. 62
36111414 2022
42
Artificial Intelligence Techniques to Predict the Airway Disorders Illness: A Systematic Review. 62
36189431 2022
43
Glycogen metabolism reprogramming promotes inflammation in coal dust-exposed lung. 62
35907323 2022
44
Workers' Occupational Dust Exposure and Pulmonary Function Assessment: Cross-Sectional Study in China. 62
36078779 2022
45
Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study. 62
36100920 2022
46
Pathology and Mineralogy Demonstrate Respirable Crystalline Silica Is a Major Cause of Severe Pneumoconiosis in U.S. Coal Miners. 62
35353671 2022
47
Deep Ensemble Learning for the Automatic Detection of Pneumoconiosis in Coal Worker's Chest X-ray Radiography. 62
36142989 2022
48
Pneumoconiosis in Coal Miners: Anthracosilicosis after All? 62
36048122 2022
49
Detection and Visualisation of Pneumoconiosis Using an Ensemble of Multi-Dimensional Deep Features Learned from Chest X-rays. 62
36141457 2022
50
Difference in Intestinal Flora and Characteristics of Plasma Metabonomics in Pneumoconiosis Patients. 62
36295819 2022

Variations for Anthracosis

Expression for Anthracosis

Search GEO for disease gene expression data for Anthracosis.

Pathways for Anthracosis

Pathways related to Anthracosis according to GeneCards Suite gene sharing:

(show all 49)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.26 TNF SOD1 IL6 IL1B CXCL8 CCL2
2
Show member pathways
13.24 TNF IL6 IL1B CXCL8 CCL2 BMP6
3
Show member pathways
12.79 TNF IL6 IL1B HSPA1L CXCL8
4
Show member pathways
12.59 TNF IL6 IL1B CXCL8 BMP6
5
Show member pathways
12.56 CXCL8 IL1B IL6 MUC5B TNF
6
Show member pathways
12.53 TNF IL6 IL1B CCL2
7
Show member pathways
12.44 TNF NLRP3 IL6 IL1B CXCL8
8
Show member pathways
12.37 CXCL8 IL1B IL6 TNF
9
Show member pathways
12.28 TNF IL6 IL1B CXCL8
10
Show member pathways
12.2 TNF MUC5B IL6 CXCL8 CCL2
11 12.13 TNF IL6 IL1B CXCL8
12 11.9 IL6 IL1B CXCL8
13 11.89 TNF IL6 IL1B CXCL8 CCL2
14
Show member pathways
11.87 TNF IL6 IL1B
15 11.85 CCL2 CXCL8 IL6
16 11.84 TNF IL6 IL1B CXCL8 CCL2
17 11.83 TNF IL1B CXCL8
18
Show member pathways
11.76 TNF NLRP3 IL1B
19
Show member pathways
11.74 IL6 CXCL8 CCL2
20 11.71 TNF IL6 IL1B
21 11.68 IL6 CXCL8 CCL2
22 11.62 TNF IL6 CXCL8
23 11.62 TNF IL6 IL1B
24
Show member pathways
11.6 TNF IL6 IL1B CXCL8
25 11.59 CCL2 CXCL8 IL1B IL6 TNF
26 11.53 CCL2 CXCL8 TNF
27 11.5 TNF IL1B CCL2
28 11.48 TNF IL6 CCL2
29 11.47 TNF IL6 CXCL8 CCL2
30 11.46 TNF IL6 IL1B
31 11.44 TNF IL6 CCL2
32 11.41 NLRP3 IL1B CARD8
33 11.33 IL6 CXCL8 CCL2
34 11.33 TNF IL6 IL1B CXCL8 CCL2
35 11.32 TNF IL6 IL1B
36 11.27 TNF IL6 IL1B
37 11.23 TNF MUC5B IL6 IL1B CXCL8 CCL2
38 11.22 TNF IL6 IL1B
39 11.18 TNF IL6 CXCL8
40 11.11 CCL2 IL1B NLRP3
41 11.03 TNF IL6 IL1B CXCL8 CCL2
42 10.99 TNF IL6 CXCL8
43 10.95 TNF IL6 IL1B CXCL8 CCL2 BMP6
44 10.9 TNF IL1B CCL2
45 10.77 IL6 IL1B
46 10.65 CCL2 CXCL8 IL6
47 10.55 TNF NLRP3 IL6 IL1B CXCL8 CCL2
48 10.5 NLRP3 IL1B
49
Show member pathways
10.24 TNF IL6 CXCL8

GO Terms for Anthracosis

Biological processes related to Anthracosis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 humoral immune response GO:0006959 10.09 TNF IL6 CCL2
2 cellular response to organic cyclic compound GO:0071407 10.08 TNF IL1B CCL2
3 protein kinase B signaling GO:0043491 10.08 TNF IL1B CCL2
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 10.07 IL1B IL6 NLRP3 TNF
5 immune response GO:0006955 10.06 TNF IL6 IL1B CXCL8 CCL2 BMP6
6 positive regulation of phagocytosis GO:0050766 10.05 TNF SOD1 IL1B
7 response to activity GO:0014823 10.04 BMP6 IL6 TNF
8 defense response to Gram-positive bacterium GO:0050830 10.04 TNF NLRP3 IL6 IL1B
9 regulation of insulin secretion GO:0050796 10.03 IL1B IL6 TNF
10 lipopolysaccharide-mediated signaling pathway GO:0031663 10 TNF IL1B CCL2
11 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.98 TNF NLRP3 CARD8
12 positive regulation of chemokine production GO:0032722 9.95 TNF IL6 IL1B
13 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.95 CARD8 IL1B TNF
14 positive regulation of interleukin-1 beta production GO:0032731 9.92 TNF NLRP3 IL6 CARD8
15 negative regulation of neurogenesis GO:0050768 9.88 TNF IL6 IL1B
16 positive regulation of glial cell proliferation GO:0060252 9.85 TNF IL6 IL1B
17 positive regulation of fever generation GO:0031622 9.84 TNF IL1B
18 sequestering of triglyceride GO:0030730 9.81 TNF IL1B
19 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.73 TNF IL1B
20 positive regulation of neuroinflammatory response GO:0150078 9.73 IL1B IL6 TNF
21 cellular response to lipopolysaccharide GO:0071222 9.7 TNF NLRP3 IL6 IL1B CXCL8 CCL2
22 vascular endothelial growth factor production GO:0010573 9.63 TNF IL6 IL1B
23 inflammatory response GO:0006954 9.53 TNF NLRP3 IL6 IL1B CXCL8 CCL2

Molecular functions related to Anthracosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.32 TNF IL6 IL1B CXCL8 CCL2 BMP6

Sources for Anthracosis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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