MCID: ANT076
MIFTS: 13

Anthracycline Extravasation

Categories: Rare diseases

Aliases & Classifications for Anthracycline Extravasation

MalaCards integrated aliases for Anthracycline Extravasation:

Name: Anthracycline Extravasation 59

Characteristics:

Orphanet epidemiological data:

59
anthracycline extravasation
Prevalence: 1-9/1000000 (Europe);

Classifications:



External Ids:

Orphanet 59 ORPHA90079
ICD10 via Orphanet 34 Y43.2

Summaries for Anthracycline Extravasation

MalaCards based summary : Anthracycline Extravasation is related to breast cancer. An important gene associated with Anthracycline Extravasation is CSF2 (Colony Stimulating Factor 2). The drugs razoxane and Topoisomerase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include breast.

Related Diseases for Anthracycline Extravasation

Diseases related to Anthracycline Extravasation via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 breast cancer 9.9

Symptoms & Phenotypes for Anthracycline Extravasation

Drugs & Therapeutics for Anthracycline Extravasation

Drugs for Anthracycline Extravasation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 razoxane Phase 2, Phase 3,Phase 3
2 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3
3 Protective Agents Phase 2, Phase 3,Phase 3
4 Antimitotic Agents Phase 2, Phase 3,Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines Completed NCT00548561 Phase 2, Phase 3 Dexrazoxane
2 A Clinical Trial on Topotect® (Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracyclines Completed NCT00548704 Phase 2, Phase 3 Dexrazoxane

Search NIH Clinical Center for Anthracycline Extravasation

Genetic Tests for Anthracycline Extravasation

Anatomical Context for Anthracycline Extravasation

MalaCards organs/tissues related to Anthracycline Extravasation:

41
Breast

Publications for Anthracycline Extravasation

Articles related to Anthracycline Extravasation:

(show all 23)
# Title Authors Year
1
Management of anthracycline extravasation into the pleural space. ( 27699056 )
2016
2
Treatment of anthracycline extravasations using dexrazoxane. ( 23949792 )
2014
3
Dexrazoxane efficacy for anthracycline extravasation: use in UK clinical practice. ( 23409691 )
2013
4
Carnitine or dimethyl sulfoxide, or both, for the treatment of anthracycline extravasation in rats. ( 23710793 )
2013
5
Dexrazoxane: a management option for anthracycline extravasations. ( 24067273 )
2013
6
BET 3: emergency management of anthracycline extravasation. ( 22903427 )
2012
7
Anthracycline extravasations: prevention and management. ( 22067533 )
2011
8
A murine experimental anthracycline extravasation model: pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage. ( 20079798 )
2010
9
Successful experience utilizing dexrazoxane treatment for an anthracycline extravasation. ( 20371757 )
2010
10
Anthracycline extravasation injuries: management with dexrazoxane. ( 19536310 )
2009
11
Anthracycline extravasation: a comprehensive review of experimental and clinical treatments. ( 19688963 )
2009
12
Dexrazoxane: new indication. Anthracycline extravasation: continue using dimethyl sulfoxide. ( 19382398 )
2009
13
The use of dexrazoxane for the prevention of anthracycline extravasation injury. ( 18230055 )
2008
14
Dexrazoxane treatment for intrathoracic anthracycline extravasation. ( 19145099 )
2008
15
Vacuum-Sealing as a Treatment Option for Severe Anthracycline Extravasation in a Breast Cancer Patient. ( 20824030 )
2008
16
Treatment of anthracycline extravasation with Savene (dexrazoxane): results from two prospective clinical multicentre studies. ( 17185744 )
2007
17
Dexrazoxane for anthracycline extravasation. ( 18028016 )
2007
18
Accidental anthracycline extravasation. ( 18090648 )
2007
19
Re: Totect: a new agent for treating anthracycline extravasation. ( 17962168 )
2007
20
Other uses of dexrazoxane: Savene, the first proven antidote against anthracycline extravasation injuries. ( 17652821 )
2007
21
Totect: a new agent for treating anthracycline extravasation. ( 17623623 )
2007
22
Management of anthracycline extravasation injuries. ( 17550954 )
2007
23
Treatment of anthracycline extravasation with dexrazoxane -- clinical experience. ( 16874015 )
2006

Variations for Anthracycline Extravasation

Expression for Anthracycline Extravasation

Search GEO for disease gene expression data for Anthracycline Extravasation.

Pathways for Anthracycline Extravasation

GO Terms for Anthracycline Extravasation

Sources for Anthracycline Extravasation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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