MCID: ANT064
MIFTS: 14

Antidepressant or Antipsychotic Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards integrated aliases for Antidepressant or Antipsychotic Toxicity or Dose Selection:

Name: Antidepressant or Antipsychotic Toxicity or Dose Selection 59

Classifications:



External Ids:

Orphanet 59 ORPHA413667

Summaries for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards based summary : Antidepressant or Antipsychotic Toxicity or Dose Selection is related to multiple chemical sensitivity and drug-induced hepatitis. Among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Serotonergic synapse.

Related Diseases for Antidepressant or Antipsychotic Toxicity or Dose Selection

Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 multiple chemical sensitivity 9.8 CYP2C19 CYP2D6
2 drug-induced hepatitis 9.8 CYP2C19 CYP2D6
3 acetaminophen metabolism 9.8 CYP2C19 CYP2D6
4 anxiety 9.8 CYP2C19 CYP2D6
5 major depressive disorder 9.7 CYP2C19 CYP2D6

Graphical network of the top 20 diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection:



Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection

Symptoms & Phenotypes for Antidepressant or Antipsychotic Toxicity or Dose Selection

Drugs & Therapeutics for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Antidepressant or Antipsychotic Toxicity or Dose Selection

Genetic Tests for Antidepressant or Antipsychotic Toxicity or Dose Selection

Anatomical Context for Antidepressant or Antipsychotic Toxicity or Dose Selection

Publications for Antidepressant or Antipsychotic Toxicity or Dose Selection

Variations for Antidepressant or Antipsychotic Toxicity or Dose Selection

Expression for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search GEO for disease gene expression data for Antidepressant or Antipsychotic Toxicity or Dose Selection.

Pathways for Antidepressant or Antipsychotic Toxicity or Dose Selection

Pathways related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.13 CYP2C19 CYP2D6
2 11.46 CYP2C19 CYP2D6
3
Show member pathways
11.3 CYP2C19 CYP2D6
4
Show member pathways
11.21 CYP2C19 CYP2D6
5
Show member pathways
11.11 CYP2C19 CYP2D6
6
Show member pathways
10.96 CYP2C19 CYP2D6
7
Show member pathways
10.55 CYP2C19 CYP2D6
8 10.19 CYP2C19 CYP2D6

GO Terms for Antidepressant or Antipsychotic Toxicity or Dose Selection

Cellular components related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular membrane-bounded organelle GO:0043231 8.96 CYP2C19 CYP2D6
2 organelle membrane GO:0031090 8.62 CYP2C19 CYP2D6

Biological processes related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.43 CYP2C19 CYP2D6
2 steroid metabolic process GO:0008202 9.4 CYP2C19 CYP2D6
3 xenobiotic metabolic process GO:0006805 9.37 CYP2C19 CYP2D6
4 drug metabolic process GO:0017144 9.32 CYP2C19 CYP2D6
5 exogenous drug catabolic process GO:0042738 9.26 CYP2C19 CYP2D6
6 organic acid metabolic process GO:0006082 9.16 CYP2C19 CYP2D6
7 heterocycle metabolic process GO:0046483 8.96 CYP2C19 CYP2D6
8 monoterpenoid metabolic process GO:0016098 8.62 CYP2C19 CYP2D6

Molecular functions related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.4 CYP2C19 CYP2D6
2 heme binding GO:0020037 9.37 CYP2C19 CYP2D6
3 iron ion binding GO:0005506 9.32 CYP2C19 CYP2D6
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2C19 CYP2D6
5 monooxygenase activity GO:0004497 9.16 CYP2C19 CYP2D6
6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.96 CYP2C19 CYP2D6
7 steroid hydroxylase activity GO:0008395 8.62 CYP2C19 CYP2D6

Sources for Antidepressant or Antipsychotic Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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