MCID: ANT064
MIFTS: 14

Antidepressant or Antipsychotic Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards integrated aliases for Antidepressant or Antipsychotic Toxicity or Dose Selection:

Name: Antidepressant or Antipsychotic Toxicity or Dose Selection 60

Classifications:



External Ids:

Orphanet 60 ORPHA413667

Summaries for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards based summary : Antidepressant or Antipsychotic Toxicity or Dose Selection is related to multiple chemical sensitivity and drug-induced hepatitis. Among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Serotonergic synapse.

Related Diseases for Antidepressant or Antipsychotic Toxicity or Dose Selection

Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 multiple chemical sensitivity 9.7 CYP2C19 CYP2D6
2 drug-induced hepatitis 9.7 CYP2C19 CYP2D6
3 acetaminophen metabolism 9.7 CYP2C19 CYP2D6
4 anxiety 9.6 CYP2C19 CYP2D6
5 major depressive disorder 9.5 CYP2C19 CYP2D6

Graphical network of the top 20 diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection:



Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection

Symptoms & Phenotypes for Antidepressant or Antipsychotic Toxicity or Dose Selection

Drugs & Therapeutics for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Antidepressant or Antipsychotic Toxicity or Dose Selection

Genetic Tests for Antidepressant or Antipsychotic Toxicity or Dose Selection

Anatomical Context for Antidepressant or Antipsychotic Toxicity or Dose Selection

Publications for Antidepressant or Antipsychotic Toxicity or Dose Selection

Variations for Antidepressant or Antipsychotic Toxicity or Dose Selection

Expression for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search GEO for disease gene expression data for Antidepressant or Antipsychotic Toxicity or Dose Selection.

Pathways for Antidepressant or Antipsychotic Toxicity or Dose Selection

Pathways related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.16 CYP2C19 CYP2D6
2 11.46 CYP2C19 CYP2D6
3
Show member pathways
11.43 CYP2C19 CYP2D6
4
Show member pathways
11.21 CYP2C19 CYP2D6
5
Show member pathways
11.11 CYP2C19 CYP2D6
6
Show member pathways
10.96 CYP2C19 CYP2D6
7
Show member pathways
10.55 CYP2C19 CYP2D6
8 10.19 CYP2C19 CYP2D6

GO Terms for Antidepressant or Antipsychotic Toxicity or Dose Selection

Cellular components related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular membrane-bounded organelle GO:0043231 8.96 CYP2C19 CYP2D6
2 organelle membrane GO:0031090 8.62 CYP2C19 CYP2D6

Biological processes related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.43 CYP2C19 CYP2D6
2 steroid metabolic process GO:0008202 9.4 CYP2C19 CYP2D6
3 xenobiotic metabolic process GO:0006805 9.37 CYP2C19 CYP2D6
4 drug metabolic process GO:0017144 9.32 CYP2C19 CYP2D6
5 exogenous drug catabolic process GO:0042738 9.26 CYP2C19 CYP2D6
6 organic acid metabolic process GO:0006082 9.16 CYP2C19 CYP2D6
7 heterocycle metabolic process GO:0046483 8.96 CYP2C19 CYP2D6
8 monoterpenoid metabolic process GO:0016098 8.62 CYP2C19 CYP2D6

Molecular functions related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.4 CYP2C19 CYP2D6
2 heme binding GO:0020037 9.37 CYP2C19 CYP2D6
3 iron ion binding GO:0005506 9.32 CYP2C19 CYP2D6
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2C19 CYP2D6
5 monooxygenase activity GO:0004497 9.16 CYP2C19 CYP2D6
6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.96 CYP2C19 CYP2D6
7 steroid hydroxylase activity GO:0008395 8.62 CYP2C19 CYP2D6

Sources for Antidepressant or Antipsychotic Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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