MCID: ANT064
MIFTS: 13

Antidepressant or Antipsychotic Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards integrated aliases for Antidepressant or Antipsychotic Toxicity or Dose Selection:

Name: Antidepressant or Antipsychotic Toxicity or Dose Selection 58

Classifications:



External Ids:

Orphanet 58 ORPHA413667

Summaries for Antidepressant or Antipsychotic Toxicity or Dose Selection

MalaCards based summary : Antidepressant or Antipsychotic Toxicity or Dose Selection is related to hypertrophy of tongue papillae and acetaminophen metabolism. An important gene associated with Antidepressant or Antipsychotic Toxicity or Dose Selection is CYP2C19 (Cytochrome P450 Family 2 Subfamily C Member 19), and among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Serotonergic synapse.

Related Diseases for Antidepressant or Antipsychotic Toxicity or Dose Selection

Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 8, show less)
# Related Disease Score Top Affiliating Genes
1 hypertrophy of tongue papillae 9.6 CYP2D6 CYP2C19
2 acetaminophen metabolism 9.6 CYP2D6 CYP2C19
3 multiple chemical sensitivity 9.6 CYP2D6 CYP2C19
4 drug-induced hepatitis 9.6 CYP2D6 CYP2C19
5 severe cutaneous adverse reaction 9.5 CYP2D6 CYP2C19
6 substance abuse 9.5 CYP2D6 CYP2C19
7 anxiety 9.4 CYP2D6 CYP2C19
8 major depressive disorder 9.2 CYP2D6 CYP2C19

Graphical network of the top 20 diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection:



Diseases related to Antidepressant or Antipsychotic Toxicity or Dose Selection

Symptoms & Phenotypes for Antidepressant or Antipsychotic Toxicity or Dose Selection

Drugs & Therapeutics for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Antidepressant or Antipsychotic Toxicity or Dose Selection

Genetic Tests for Antidepressant or Antipsychotic Toxicity or Dose Selection

Anatomical Context for Antidepressant or Antipsychotic Toxicity or Dose Selection

Publications for Antidepressant or Antipsychotic Toxicity or Dose Selection

Variations for Antidepressant or Antipsychotic Toxicity or Dose Selection

Expression for Antidepressant or Antipsychotic Toxicity or Dose Selection

Search GEO for disease gene expression data for Antidepressant or Antipsychotic Toxicity or Dose Selection.

Pathways for Antidepressant or Antipsychotic Toxicity or Dose Selection

Pathways related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

(showing 9, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.18 CYP2D6 CYP2C19
2 11.49 CYP2D6 CYP2C19
3
Show member pathways
11.46 CYP2D6 CYP2C19
4
Show member pathways
11.38 CYP2D6 CYP2C19
5
Show member pathways
11.2 CYP2D6 CYP2C19
6
Show member pathways
11.06 CYP2D6 CYP2C19
7
Show member pathways
10.75 CYP2D6 CYP2C19
8 10.52 CYP2D6 CYP2C19
9
Show member pathways
10.15 CYP2D6 CYP2C19

GO Terms for Antidepressant or Antipsychotic Toxicity or Dose Selection

Cellular components related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.62 CYP2D6 CYP2C19

Biological processes related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

(showing 10, show less)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.48 CYP2D6 CYP2C19
2 lipid metabolic process GO:0006629 9.46 CYP2D6 CYP2C19
3 fatty acid metabolic process GO:0006631 9.43 CYP2D6 CYP2C19
4 steroid metabolic process GO:0008202 9.4 CYP2D6 CYP2C19
5 xenobiotic metabolic process GO:0006805 9.37 CYP2D6 CYP2C19
6 exogenous drug catabolic process GO:0042738 9.32 CYP2D6 CYP2C19
7 drug metabolic process GO:0017144 9.26 CYP2D6 CYP2C19
8 organic acid metabolic process GO:0006082 9.16 CYP2D6 CYP2C19
9 heterocycle metabolic process GO:0046483 8.96 CYP2D6 CYP2C19
10 monoterpenoid metabolic process GO:0016098 8.62 CYP2D6 CYP2C19

Molecular functions related to Antidepressant or Antipsychotic Toxicity or Dose Selection according to GeneCards Suite gene sharing:

(showing 7, show less)
# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.4 CYP2D6 CYP2C19
2 heme binding GO:0020037 9.37 CYP2D6 CYP2C19
3 iron ion binding GO:0005506 9.32 CYP2D6 CYP2C19
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2D6 CYP2C19
5 monooxygenase activity GO:0004497 9.16 CYP2D6 CYP2C19
6 steroid hydroxylase activity GO:0008395 8.96 CYP2D6 CYP2C19
7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.62 CYP2D6 CYP2C19

Sources for Antidepressant or Antipsychotic Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....