MSK1
MCID: ANT080
MIFTS: 18

Antigen Defined by Monoclonal Antibody Aj9 (MSK1)

Categories: Immune diseases

Aliases & Classifications for Antigen Defined by Monoclonal Antibody Aj9

MalaCards integrated aliases for Antigen Defined by Monoclonal Antibody Aj9:

Name: Antigen Defined by Monoclonal Antibody Aj9 56
Msk1 56

Classifications:



External Ids:

OMIM 56 158030

Summaries for Antigen Defined by Monoclonal Antibody Aj9

MalaCards based summary : Antigen Defined by Monoclonal Antibody Aj9, also known as msk1, is related to antigen defined by monoclonal antibody t87 and craniosynostosis with fibular aplasia. Affiliated tissues include breast, skin and brain.

More information from OMIM: 158030

Related Diseases for Antigen Defined by Monoclonal Antibody Aj9

Diseases in the Antigen Defined by Monoclonal Antibody Aj9 family:

Antigen Defined by Monoclonal Antibody T87

Diseases related to Antigen Defined by Monoclonal Antibody Aj9 via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 antigen defined by monoclonal antibody t87 10.6
2 craniosynostosis with fibular aplasia 10.2
3 coffin-lowry syndrome 10.2
4 microphthalmia 10.2
5 b-cell lymphoma 10.2
6 spinal cord injury 10.2
7 breast cancer 10.0
8 colorectal cancer 10.0
9 neutrophil migration 10.0
10 pheochromocytoma 10.0
11 proteasome-associated autoinflammatory syndrome 1 10.0
12 leukemia, acute myeloid 10.0
13 muscle hypertrophy 10.0
14 helix syndrome 10.0
15 adrenal gland pheochromocytoma 10.0
16 leukemia 10.0
17 dermatitis 10.0
18 mood disorder 10.0
19 skin carcinoma 10.0
20 pustulosis of palm and sole 10.0
21 myeloid leukemia 10.0
22 psoriasis 10.0
23 brain injury 10.0
24 traumatic brain injury 10.0

Graphical network of the top 20 diseases related to Antigen Defined by Monoclonal Antibody Aj9:



Diseases related to Antigen Defined by Monoclonal Antibody Aj9

Symptoms & Phenotypes for Antigen Defined by Monoclonal Antibody Aj9

Clinical features from OMIM:

158030

Drugs & Therapeutics for Antigen Defined by Monoclonal Antibody Aj9

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Trial Readiness for SCA1 and SCA3 Recruiting NCT03487367

Search NIH Clinical Center for Antigen Defined by Monoclonal Antibody Aj9

Genetic Tests for Antigen Defined by Monoclonal Antibody Aj9

Anatomical Context for Antigen Defined by Monoclonal Antibody Aj9

MalaCards organs/tissues related to Antigen Defined by Monoclonal Antibody Aj9:

40
Breast, Skin, Brain, Cardiac Myocytes, Skeletal Muscle, Lung, Endothelial

Publications for Antigen Defined by Monoclonal Antibody Aj9

Articles related to Antigen Defined by Monoclonal Antibody Aj9:

(show top 50) (show all 400)
# Title Authors PMID Year
1
Two cell-surface markers for human chromosome 1 in interspecies hybrids. 56
6585973 1984
2
Experience Recruits MSK1 to Expand the Dynamic Range of Synapses and Enhance Cognition. 61
32376781 2020
3
Immuno-metabolic impact of the multiple sclerosis patients' sera on endothelial cells of the blood-brain barrier. 61
32386505 2020
4
Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis. 61
32284328 2020
5
Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling. 61
32408395 2020
6
A proteomic signature for CNS adaptations to the valence of environmental stimulation. 61
32006564 2020
7
STAT3 activates MSK1-mediated histone H3 phosphorylation to promote NFAT signaling in gastric carcinogenesis. 61
32041943 2020
8
Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis: A Demonstration of the Effect on Peripheral Blood Mononuclear Cells, Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate. 61
32309199 2020
9
TRAF2 Knockdown in Nasopharyngeal Carcinoma Induced Cell Cycle Arrest and Enhanced the Sensitivity to Radiotherapy. 61
32566659 2020
10
Soluble PTX3 of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuates Hyperoxic Lung Injury by Activating Macrophage Polarization in Neonatal Rat Model. 61
32399038 2020
11
Activation of Toll-Like Receptor 3 Induces Interleukin-1 Receptor Antagonist Expression by Activating the Interferon Regulatory Factor 3. 61
31865314 2019
12
Chemogenomic Analysis of the Druggable Kinome and Its Application to Repositioning and Lead Identification Studies. 61
31521622 2019
13
Oncogenic Ras mutant causes the hyperactivation of NF-κB via acceleration of its transcriptional activation. 61
31580526 2019
14
An Angle on MK2 Inhibition-Optimization and Evaluation of Prevention of Activation Inhibitors. 61
31325352 2019
15
Novel Insights into MSK1 Phosphorylation by MRKβ in Intracerebral Hemorrhage-Induced Neuronal Apoptosis. 61
30744416 2019
16
Inhibition of MSK1 Promotes Inflammation and Apoptosis and Inhibits Functional Recovery After Spinal Cord Injury. 61
30919247 2019
17
Quercetin conjugated with superparamagnetic iron oxide nanoparticles improves learning and memory better than free quercetin via interacting with proteins involved in LTP. 61
31053743 2019
18
Role of MSK1 in the Induction of NF-κB by the Chemokine CX3CL1 in Microglial Cells. 61
30830503 2019
19
Risperidone effects on heterochromatin: the role of kinase signaling. 61
30714144 2019
20
Intracellular Signaling Mechanisms Involved in the Biological Effects of the Xanthophyll Carotenoid Astaxanthin to Prevent the Photo-aging of the Skin in a Reactive Oxygen Species Depletion-independent Manner: The Key Role of Mitogen and Stress-activated Protein Kinase 1. 61
30317634 2019
21
EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases. 61
30679314 2019
22
MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sjögren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1. 61
31281310 2019
23
Phosphothreonine Lyase Promotes p65 Degradation in a Mitogen-Activated Protein Kinase/Mitogen- and Stress-Activated Protein Kinase 1-Dependent Manner. 61
30396897 2019
24
Excessive Neutrophil Extracellular Trap Formation Aggravates Acute Myocardial Infarction Injury in Apolipoprotein E Deficiency Mice via the ROS-Dependent Pathway. 61
31249639 2019
25
Histone H3 Serine 10 Phosphorylation Facilitates Endothelial Activation in Diabetic Kidney Disease. 61
30213824 2018
26
Aloe emodin suppresses EGF‑induced neoplastic cell transformation by inhibiting the ERK/MSK1 and AKT/GSK3β signaling pathways. 61
30272294 2018
27
High expression of mitogen-activated and stress-activated protein kinase 1 indicates poor prognosis in patients with glioma. 61
30020192 2018
28
MSK1 functions as a transcriptional coactivator of p53 in the regulation of p21 gene expression. 61
30305627 2018
29
Strategies of biochemical adaptation for hibernation in a South American marsupial Dromiciops gliroides: 1. Mitogen-activated protein kinases and the cell stress response. 61
29247845 2018
30
Exclusive enteral nutrition protects against inflammatory bowel disease by inhibiting NF‑κB activation through regulation of the p38/MSK1 pathway. 61
29901086 2018
31
Publisher Correction: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer. 61
29674681 2018
32
PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1. 61
29860311 2018
33
[Effect of lentivirus-mediated small interfering RNA on mitogen- and stress-activated protein kinase 1 in spinal cord injury of rats]. 61
30129321 2018
34
Signaling Cascades Activated by UVB in Human Melanocytes Lead to the Increased Expression of Melanocyte Receptors, Endothelin B Receptor and c-KIT. 61
28977677 2018
35
The stem cell factor-stimulated melanogenesis in human melanocytes can be abrogated by interrupting the phosphorylation of MSK1: evidence for involvement of the p38/MSK1/CREB/MITF axis. 61
29362867 2018
36
High nuclear MSK1 is associated with longer survival in breast cancer patients. 61
29327245 2018
37
Selective Activation of Striatal NGF-TrkA/p75NTR/MAPK Intracellular Signaling in Rats That Show Suppression of Methamphetamine Intake 30 Days following Drug Abstinence. 61
29165617 2018
38
MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer. 61
29358704 2018
39
Illuminating MSK1's role in tumour dormancy. 61
29371707 2018
40
Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB. 61
29495390 2018
41
Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α. 61
29290625 2018
42
Astragalin Attenuates UVB Radiation-induced Actinic Keratosis Formation. 61
29298652 2018
43
Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells. 61
30323812 2018
44
Mitogen- and stress-activated protein kinase 1 is required for gonadotropin-releasing hormone-mediated activation of gonadotropin α-subunit expression. 61
29054929 2017
45
The Specific Mitogen- and Stress-Activated Protein Kinase MSK1 Inhibitor SB-747651A Modulates Chemokine-Induced Neutrophil Recruitment. 61
29039777 2017
46
ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB. 61
28721437 2017
47
Reactive oxygen species mediated NF-κB/p38 feedback loop implicated in proliferation inhibition of HFLS-RA cells induced by 1,7-dihydroxy-3,4-dimethoxyxanthone. 61
28810523 2017
48
Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the Hippocampus. 61
28870089 2017
49
MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats. 61
28927047 2017
50
Aldosterone activates the oncogenic signals ERK1/2 and STAT3 via redox-regulated mechanisms. 61
28272757 2017

Variations for Antigen Defined by Monoclonal Antibody Aj9

Expression for Antigen Defined by Monoclonal Antibody Aj9

Search GEO for disease gene expression data for Antigen Defined by Monoclonal Antibody Aj9.

Pathways for Antigen Defined by Monoclonal Antibody Aj9

GO Terms for Antigen Defined by Monoclonal Antibody Aj9

Sources for Antigen Defined by Monoclonal Antibody Aj9

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57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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