MSK2
MCID: ANT081
MIFTS: 13

Antigen Defined by Monoclonal Antibody T87 (MSK2)

Categories: Immune diseases

Aliases & Classifications for Antigen Defined by Monoclonal Antibody T87

MalaCards integrated aliases for Antigen Defined by Monoclonal Antibody T87:

Name: Antigen Defined by Monoclonal Antibody T87 56
Msk2 56

Classifications:



External Ids:

OMIM 56 158040

Summaries for Antigen Defined by Monoclonal Antibody T87

MalaCards based summary : Antigen Defined by Monoclonal Antibody T87, also known as msk2, is related to antigen defined by monoclonal antibody aj9 and retinoblastoma. Affiliated tissues include skin, skeletal muscle and smooth muscle.

More information from OMIM: 158040

Related Diseases for Antigen Defined by Monoclonal Antibody T87

Diseases in the Antigen Defined by Monoclonal Antibody Aj9 family:

Antigen Defined by Monoclonal Antibody T87

Diseases related to Antigen Defined by Monoclonal Antibody T87 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 antigen defined by monoclonal antibody aj9 10.7
2 retinoblastoma 10.2
3 cervical cancer 10.2
4 dermatitis 10.2
5 familial retinoblastoma 10.2

Graphical network of the top 20 diseases related to Antigen Defined by Monoclonal Antibody T87:



Diseases related to Antigen Defined by Monoclonal Antibody T87

Symptoms & Phenotypes for Antigen Defined by Monoclonal Antibody T87

Clinical features from OMIM:

158040

Drugs & Therapeutics for Antigen Defined by Monoclonal Antibody T87

Search Clinical Trials , NIH Clinical Center for Antigen Defined by Monoclonal Antibody T87

Genetic Tests for Antigen Defined by Monoclonal Antibody T87

Anatomical Context for Antigen Defined by Monoclonal Antibody T87

MalaCards organs/tissues related to Antigen Defined by Monoclonal Antibody T87:

40
Skin, Skeletal Muscle, Smooth Muscle, Colon, Breast

Publications for Antigen Defined by Monoclonal Antibody T87

Articles related to Antigen Defined by Monoclonal Antibody T87:

(show all 45)
# Title Authors PMID Year
1
MSK2 promotes proliferation and tumor formation in squamous cervical cancer via PAX8/RB-E2F1/cyclin A2 axis. 61
30756420 2019
2
Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro. 61
31889894 2019
3
Possible role of ginsenoside Rb1 in skin wound healing via regulating senescent skin dermal fibroblast. 61
29577907 2018
4
High nuclear MSK1 is associated with longer survival in breast cancer patients. 61
29327245 2018
5
Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. 61
29991026 2018
6
Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation. 61
28816616 2018
7
Epigenetic Activation of μ-Opioid Receptor Gene via Increased Expression and Function of Mitogen- and Stress-Activated Protein Kinase 1. 61
28153853 2017
8
miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. 61
27350436 2016
9
Emerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2. 61
27376065 2016
10
The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development. 61
27973548 2016
11
Mitogen and stress-activated kinases 1/2 regulate ischemia-induced hippocampal progenitor cell proliferation and neurogenesis. 61
25451279 2015
12
Mouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 Residue. 61
26642194 2015
13
Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeres. 61
24821703 2014
14
Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes. 61
24792438 2014
15
The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation. 61
24519526 2014
16
Statins and musculoskeletal conditions, arthropathies, and injuries. 61
23877079 2013
17
MSK1 and MSK2 inhibit lipopolysaccharide-induced prostaglandin production via an interleukin-10 feedback loop. 61
23382072 2013
18
Sunlight UV-induced skin cancer relies upon activation of the p38α signaling pathway. 61
23382047 2013
19
Secondary metabolites from Marchantia paleacea calluses and their allelopathic effects on Arabidopsis seed growth. 61
22400496 2013
20
Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction. 61
23675462 2013
21
Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus. 61
23020821 2012
22
Characterization of the cellular action of the MSK inhibitor SB-747651A. 61
21970321 2012
23
HCV-induced PKR activation is stimulated by the mitogen- and stress-activated protein kinase MSK2. 61
21385567 2011
24
Mice lacking MSK1 and MSK2 show reduced skin tumor development in a two-stage chemical carcinogenesis model. 61
21314333 2011
25
Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients. 61
20805296 2011
26
Differential regulation of mitogen- and stress-activated protein kinase-1 and -2 (MSK1 and MSK2) by CK2 following UV radiation. 61
19933278 2010
27
MSK2 inhibits p53 activity in the absence of stress. 61
19797274 2009
28
Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. 61
19592492 2009
29
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. 61
18690222 2008
30
Dual enzyme-linked immunosorbent assay system for detection of endogenous kinase activities of mitogen- and stress-activated protein kinase-1/2. 61
17767420 2007
31
Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis. 61
17429437 2007
32
Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS. 61
17117922 2007
33
Evidence that N-acetylcysteine inhibits TNF-alpha-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase. 61
17023264 2006
34
The kinases MSK1 and MSK2 are required for epidermal growth factor-induced, but not tumor necrosis factor-induced, histone H3 Ser10 phosphorylation. 61
16517600 2006
35
MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling. 61
15910281 2005
36
p90 ribosomal S6 kinase 2 is associated with and dephosphorylated by protein phosphatase 2Cdelta. 61
15206906 2004
37
MSK1 and MSK2 mediate mitogen- and stress-induced phosphorylation of histone H3: a controversy resolved. 61
12915720 2003
38
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. 61
12773393 2003
39
MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts. 61
11909979 2002
40
Construction of a conditional allele of RSK-B/MSK2 in the mouse. 61
11857808 2002
41
Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle. 61
11557517 2001
42
Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle. 61
11579175 2001
43
Effects of exercise on mitogen- and stress-activated kinase signal transduction in human skeletal muscle. 61
11049854 2000
44
Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages. 61
10706690 2000
45
Genomic organization of the mouse and human genes encoding the ATP sulfurylase/adenosine 5'-phosphosulfate kinase isoform SK2. 61
10559207 1999

Variations for Antigen Defined by Monoclonal Antibody T87

Expression for Antigen Defined by Monoclonal Antibody T87

Search GEO for disease gene expression data for Antigen Defined by Monoclonal Antibody T87.

Pathways for Antigen Defined by Monoclonal Antibody T87

GO Terms for Antigen Defined by Monoclonal Antibody T87

Sources for Antigen Defined by Monoclonal Antibody T87

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61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
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70 Tocris
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72 UMLS via Orphanet
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