MCID: ANT078
MIFTS: 26

Antipyrine Metabolism

Categories: Metabolic diseases

Aliases & Classifications for Antipyrine Metabolism

MalaCards integrated aliases for Antipyrine Metabolism:

Name: Antipyrine Metabolism 57 73

Classifications:



External Ids:

OMIM 57 107290
UMLS 73 C1862824

Summaries for Antipyrine Metabolism

MalaCards based summary : Antipyrine Metabolism is related to liver disease and alcoholic liver cirrhosis. An important gene associated with Antipyrine Metabolism is ALB (Albumin), and among its related pathways/superpathways are Selenium Micronutrient Network and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include liver, lung and thyroid.

Description from OMIM: 107290

Related Diseases for Antipyrine Metabolism

Diseases related to Antipyrine Metabolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 liver disease 29.7 F2 ALB
2 alcoholic liver cirrhosis 29.7 F2 ALB
3 liver cirrhosis 29.7 F2 ALB
4 colorectal cancer 10.0
5 lung cancer 10.0
6 diabetes mellitus 10.0
7 non-a-e hepatitis 10.0 F2 ALB
8 epstein-barr virus hepatitis 10.0 F2 ALB
9 fournier gangrene 10.0 F2 ALB
10 abdominal tuberculosis 10.0 F2 ALB
11 hepatic tuberculosis 10.0 F2 ALB
12 kwashiorkor 10.0 F2 ALB
13 hepatic coma 10.0 F2 ALB
14 infantile liver failure syndrome 1 10.0 F2 ALB
15 splenic disease 10.0 F2 ALB
16 ascending cholangitis 10.0 F2 ALB
17 cholangitis 10.0 F2 ALB
18 esophageal varix 10.0 F2 ALB
19 hypersplenism 10.0 F2 ALB
20 hemorrhagic fever 10.0 F2 ALB
21 compartment syndrome 10.0 F2 ALB
22 hepatorenal syndrome 10.0 F2 ALB
23 choledocholithiasis 10.0 F2 ALB
24 dysfibrinogenemia 10.0 F2 ALB
25 pulmonary artery disease 9.9 F2 ALB
26 hepatic vascular disease 9.9 F2 ALB
27 vascular disease 9.9 F2 ALB
28 autoimmune disease of urogenital tract 9.9 F2 ALB
29 analbuminemia 9.9 F2 ALB
30 acute liver failure 9.9 F2 ALB
31 hepatitis e 9.9 F2 ALB
32 vein disease 9.9 ALB F2
33 intermittent claudication 9.9 ALB F2
34 bile duct disease 9.9 ALB F2
35 hepatitis a 9.9 ALB F2
36 typhoid fever 9.9 ALB F2
37 cholecystitis 9.9 ALB F2
38 bilirubin metabolic disorder 9.9 ALB F2
39 dengue hemorrhagic fever 9.9 ALB F2
40 biliary tract disease 9.9 ALB F2
41 obstructive jaundice 9.9 ALB F2
42 hepatic encephalopathy 9.9 ALB F2
43 homocysteinemia 9.9 F2 ALB
44 endocarditis 9.9 F2 ALB
45 alcoholic hepatitis 9.9 F2 ALB
46 pulmonary embolism 9.9 F2 ALB
47 portal hypertension 9.9 F2 ALB
48 peripheral vascular disease 9.9 F2 ALB
49 wilson disease 9.9 F2 ALB
50 polycystic liver disease 1 with or without kidney cysts 9.9

Graphical network of the top 20 diseases related to Antipyrine Metabolism:



Diseases related to Antipyrine Metabolism

Symptoms & Phenotypes for Antipyrine Metabolism

Clinical features from OMIM:

107290

Drugs & Therapeutics for Antipyrine Metabolism

Search Clinical Trials , NIH Clinical Center for Antipyrine Metabolism

Genetic Tests for Antipyrine Metabolism

Anatomical Context for Antipyrine Metabolism

MalaCards organs/tissues related to Antipyrine Metabolism:

41
Liver, Lung, Thyroid, Testes, Kidney, Heart

Publications for Antipyrine Metabolism

Articles related to Antipyrine Metabolism:

(show top 50) (show all 105)
# Title Authors Year
1
Impact of dioxins on antipyrine metabolism in firefighters. ( 27067104 )
2016
2
Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion. ( 12926547 )
2003
3
Effect of experimental fasciolosis on antipyrine metabolism and clearance in water buffaloes. ( 10714456 )
2000
4
Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity. ( 10678296 )
2000
5
The effect of sex on antipyrine metabolism in cattle at different ages. ( 10447826 )
1999
6
Antipyrine metabolism in lung cancer patients and their relatives. ( 9337547 )
1997
7
The effect of cimetidine on antipyrine metabolism in calves. ( 9049953 )
1997
8
Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( 8869667 )
1996
9
Effect of spironolactone on antipyrine metabolism in calves. ( 8819201 )
1996
10
Relationship between antipyrine metabolism and acetylation phenotype in health and chronic liver diseases. ( 7665722 )
1995
11
Antipyrine Metabolism during Chemotherapy with 5-Fluorouracil Plus Folinic Acid in Patients with Liver Metastases from Primary Colorectal Cancer. ( 11835096 )
1994
12
Inhibitory action of cimetidine on antipyrine metabolism. ( 8118484 )
1993
13
[Antipyrine metabolism in lung cancer patients]. ( 8111326 )
1993
14
Antipyrine metabolism in patients with liver metastases from colorectal cancer. ( 1515999 )
1992
15
Antipyrine metabolism in coke oven workers. ( 1805733 )
1991
16
The influence of Org 10172, a low molecular weight heparinoid, on antipyrine metabolism and the effect of enzyme induction on the response to Org 10172. ( 1716140 )
1991
17
Inhibition of antipyrine metabolism by low-dose contraceptives with gestodene and desogestrel. ( 1826096 )
1991
18
Metronidazole and antipyrine metabolism in the rat: clearance determination from one saliva sample. ( 2003365 )
1991
19
Non-alcoholic steatohepatitis: impaired antipyrine metabolism and hypertriglyceridaemia may be clues to its pathogenesis. ( 1782374 )
1991
20
Influence of the method of fluosol-DA administration on antipyrine metabolism in the rat. ( 1982312 )
1990
21
Ranitidine alters antipyrine metabolism in control and phenobarbital-treated mice. ( 2084458 )
1990
22
Short term anti-tubercular drug therapy and hepatic microsomal enzyme activity. Antipyrine metabolism as an index. ( 2266077 )
1990
23
Hepatic antipyrine metabolism in athletes. ( 2266756 )
1990
24
Quinidine does not alter antipyrine metabolism. ( 2312782 )
1990
25
Impairment of human antipyrine metabolism by piroxicam. ( 2372742 )
1990
26
Sex difference in antipyrine 3-hydroxylation. An in vivo-in vitro correlation of antipyrine metabolism in two rat strains. ( 2386545 )
1990
27
The influence of antineoplastic chemotherapy on antipyrine metabolism in man. ( 2498398 )
1989
28
Fluconazole is a potent inhibitor of antipyrine metabolism in vivo in mice. ( 2566469 )
1989
29
Biostin (RU-41740) does not impair antipyrine metabolism in healthy volunteers. ( 2586200 )
1989
30
The effect of moderately severe hemodilution with Fluosol-DA on cytochrome P-450 mediated antipyrine metabolism. ( 2605353 )
1989
31
Antipyrine metabolism is not affected by terbinafine, a new antifungal agent. ( 2612536 )
1989
32
Effects of endophyte-infected fescue and cimetidine on respiration rates, rectal temperatures and hepatic mixed function oxidase activity as measured by hepatic antipyrine metabolism in sheep. ( 2613583 )
1989
33
Antipyrine metabolism in female Lewis and Dark Agouti strains of rats, which are extensive and poor metabolizers of debrisoquine, respectively. ( 2747044 )
1989
34
Influence of rifampicin on thyroid gland volume, thyroid hormones, and antipyrine metabolism. ( 2800919 )
1989
35
The effect of age on antipyrine metabolism by liver microsomes isolated from phenobarbital-treated rats. ( 2811495 )
1989
36
The effect of varying percentages of haemodilution with fluosol-DA or normal saline on antipyrine metabolism in the rat. ( 2901469 )
1988
37
The effect of ciprofloxacin on antipyrine metabolism. ( 3170391 )
1988
38
Antipyrine metabolism in acute hepatic porphyria in relapse and remission. ( 3567053 )
1987
39
Studies on in vitro antipyrine metabolism by 13C,15N double labeled method. ( 3298908 )
1987
40
Antipyrine metabolism in the Venda. ( 3557469 )
1987
41
Inhibition and induction of metronidazole and antipyrine metabolism. ( 3582467 )
1987
42
Comparison of effects of ozone, cadmium chloride and carbon tetrachloride on [14C]antipyrine metabolism in conscious rats. ( 3624772 )
1987
43
Antipyrine metabolism in cultured rat hepatocytes. ( 3632725 )
1987
44
Antipyrine metabolism not influenced by level of carbohydrate intake. ( 3691321 )
1987
45
Dynamic interactions among host factors that influence antipyrine metabolism: implications for the design and interpretation of studies on ethnic pharmacokinetic variations. ( 3523515 )
1986
46
Inhibition of antipyrine metabolism by interferon. ( 3790409 )
1986
47
The pharmacokinetics of mefloquine in man: lack of effect of mefloquine on antipyrine metabolism. ( 3878153 )
1985
48
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator. ( 4087137 )
1985
49
Investigations on antipyrine metabolism V. Differentiation of two isomeric hydroxyantipyrine glucuronides by field desorption and fast atom bombardment mass spectrometry. ( 3161551 )
1985
50
Hepatic antipyrine metabolism in malnourished patients: influence of the type of malnutrition and course after nutritional rehabilitation. ( 3923817 )
1985

Variations for Antipyrine Metabolism

Expression for Antipyrine Metabolism

Search GEO for disease gene expression data for Antipyrine Metabolism.

Pathways for Antipyrine Metabolism

Pathways related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 ALB F2
2 10.27 ALB F2

GO Terms for Antipyrine Metabolism

Cellular components related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 8.96 ALB F2
2 blood microparticle GO:0072562 8.62 ALB F2

Biological processes related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.62 ALB F2

Sources for Antipyrine Metabolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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