MCID: ANT078
MIFTS: 25

Antipyrine Metabolism

Categories: Metabolic diseases

Aliases & Classifications for Antipyrine Metabolism

MalaCards integrated aliases for Antipyrine Metabolism:

Name: Antipyrine Metabolism 58 74

Classifications:



External Ids:

OMIM 58 107290
UMLS 74 C1862824

Summaries for Antipyrine Metabolism

MalaCards based summary : Antipyrine Metabolism is related to alcoholic liver cirrhosis and liver cirrhosis. An important gene associated with Antipyrine Metabolism is ALB (Albumin), and among its related pathways/superpathways are Selenium Micronutrient Network and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include liver, lung and thyroid.

Description from OMIM: 107290

Related Diseases for Antipyrine Metabolism

Diseases related to Antipyrine Metabolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 alcoholic liver cirrhosis 29.6 ALB F2
2 liver cirrhosis 29.6 ALB F2
3 liver disease 29.6 ALB F2
4 colorectal cancer 10.0
5 lung cancer 10.0
6 diabetes mellitus 10.0
7 non-a-e hepatitis 9.9 ALB F2
8 epstein-barr virus hepatitis 9.9 ALB F2
9 fournier gangrene 9.9 ALB F2
10 abdominal tuberculosis 9.9 ALB F2
11 hepatic tuberculosis 9.9 ALB F2
12 kwashiorkor 9.9 ALB F2
13 hepatic coma 9.9 ALB F2
14 infantile liver failure syndrome 1 9.9 ALB F2
15 splenic disease 9.9 ALB F2
16 esophageal varix 9.9 ALB F2
17 ascending cholangitis 9.9 ALB F2
18 cholangitis 9.9 ALB F2
19 hypersplenism 9.9 ALB F2
20 compartment syndrome 9.9 ALB F2
21 hepatorenal syndrome 9.9 ALB F2
22 choledocholithiasis 9.9 ALB F2
23 analbuminemia 9.9 ALB F2
24 autoimmune disease of urogenital tract 9.9 ALB F2
25 hepatic vascular disease 9.9 ALB F2
26 vascular disease 9.9 ALB F2
27 pulmonary artery disease 9.9 ALB F2
28 dysfibrinogenemia 9.9 ALB F2
29 acute liver failure 9.9 ALB F2
30 hepatitis e 9.9 ALB F2
31 vein disease 9.9 ALB F2
32 intermittent claudication 9.9 ALB F2
33 bile duct disease 9.9 ALB F2
34 polycystic liver disease 1 with or without kidney cysts 9.9
35 hemochromatosis, type 1 9.9
36 gastric cancer 9.9
37 alcohol abuse 9.9
38 polycystic liver disease 9.9
39 cholelithiasis 9.9
40 bronchus cancer 9.9
41 porphyria 9.9
42 iron metabolism disease 9.9
43 testicular cancer 9.9
44 juvenile hereditary hemochromatosis 9.9
45 nonalcoholic steatohepatitis 9.9
46 hypoxia 9.9
47 hepatitis a 9.9 ALB F2
48 typhoid fever 9.9 ALB F2
49 cholecystitis 9.9 ALB F2
50 bilirubin metabolic disorder 9.9 ALB F2

Graphical network of the top 20 diseases related to Antipyrine Metabolism:



Diseases related to Antipyrine Metabolism

Symptoms & Phenotypes for Antipyrine Metabolism

Clinical features from OMIM:

107290

Drugs & Therapeutics for Antipyrine Metabolism

Search Clinical Trials , NIH Clinical Center for Antipyrine Metabolism

Genetic Tests for Antipyrine Metabolism

Anatomical Context for Antipyrine Metabolism

MalaCards organs/tissues related to Antipyrine Metabolism:

42
Liver, Lung, Thyroid, Testes, Kidney, Heart

Publications for Antipyrine Metabolism

Articles related to Antipyrine Metabolism:

(show top 50) (show all 105)
# Title Authors Year
1
Impact of dioxins on antipyrine metabolism in firefighters. ( 27067104 )
2016
2
Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion. ( 12926547 )
2003
3
Effect of experimental fasciolosis on antipyrine metabolism and clearance in water buffaloes. ( 10714456 )
2000
4
Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity. ( 10678296 )
2000
5
The effect of sex on antipyrine metabolism in cattle at different ages. ( 10447826 )
1999
6
Antipyrine metabolism in lung cancer patients and their relatives. ( 9337547 )
1997
7
The effect of cimetidine on antipyrine metabolism in calves. ( 9049953 )
1997
8
Effect of spironolactone on antipyrine metabolism in calves. ( 8819201 )
1996
9
Effect of alcohol abuse and glutathione administration on the circulating levels of glutathione and on antipyrine metabolism in patients with alcoholic liver cirrhosis. ( 8869667 )
1996
10
Relationship between antipyrine metabolism and acetylation phenotype in health and chronic liver diseases. ( 7665722 )
1995
11
Antipyrine Metabolism during Chemotherapy with 5-Fluorouracil Plus Folinic Acid in Patients with Liver Metastases from Primary Colorectal Cancer. ( 11835096 )
1994
12
Inhibitory action of cimetidine on antipyrine metabolism. ( 8118484 )
1993
13
[Antipyrine metabolism in lung cancer patients]. ( 8111326 )
1993
14
Antipyrine metabolism in patients with liver metastases from colorectal cancer. ( 1515999 )
1992
15
Metronidazole and antipyrine metabolism in the rat: clearance determination from one saliva sample. ( 2003365 )
1991
16
Inhibition of antipyrine metabolism by low-dose contraceptives with gestodene and desogestrel. ( 1826096 )
1991
17
Antipyrine metabolism in coke oven workers. ( 1805733 )
1991
18
Non-alcoholic steatohepatitis: impaired antipyrine metabolism and hypertriglyceridaemia may be clues to its pathogenesis. ( 1782374 )
1991
19
The influence of Org 10172, a low molecular weight heparinoid, on antipyrine metabolism and the effect of enzyme induction on the response to Org 10172. ( 1716140 )
1991
20
Sex difference in antipyrine 3-hydroxylation. An in vivo-in vitro correlation of antipyrine metabolism in two rat strains. ( 2386545 )
1990
21
Impairment of human antipyrine metabolism by piroxicam. ( 2372742 )
1990
22
Quinidine does not alter antipyrine metabolism. ( 2312782 )
1990
23
Hepatic antipyrine metabolism in athletes. ( 2266756 )
1990
24
Short term anti-tubercular drug therapy and hepatic microsomal enzyme activity. Antipyrine metabolism as an index. ( 2266077 )
1990
25
Ranitidine alters antipyrine metabolism in control and phenobarbital-treated mice. ( 2084458 )
1990
26
Influence of the method of fluosol-DA administration on antipyrine metabolism in the rat. ( 1982312 )
1990
27
The effect of age on antipyrine metabolism by liver microsomes isolated from phenobarbital-treated rats. ( 2811495 )
1989
28
Influence of rifampicin on thyroid gland volume, thyroid hormones, and antipyrine metabolism. ( 2800919 )
1989
29
Antipyrine metabolism in female Lewis and Dark Agouti strains of rats, which are extensive and poor metabolizers of debrisoquine, respectively. ( 2747044 )
1989
30
Effects of endophyte-infected fescue and cimetidine on respiration rates, rectal temperatures and hepatic mixed function oxidase activity as measured by hepatic antipyrine metabolism in sheep. ( 2613583 )
1989
31
Antipyrine metabolism is not affected by terbinafine, a new antifungal agent. ( 2612536 )
1989
32
The effect of moderately severe hemodilution with Fluosol-DA on cytochrome P-450 mediated antipyrine metabolism. ( 2605353 )
1989
33
Biostin (RU-41740) does not impair antipyrine metabolism in healthy volunteers. ( 2586200 )
1989
34
Fluconazole is a potent inhibitor of antipyrine metabolism in vivo in mice. ( 2566469 )
1989
35
The influence of antineoplastic chemotherapy on antipyrine metabolism in man. ( 2498398 )
1989
36
The effect of ciprofloxacin on antipyrine metabolism. ( 3170391 )
1988
37
The effect of varying percentages of haemodilution with fluosol-DA or normal saline on antipyrine metabolism in the rat. ( 2901469 )
1988
38
Antipyrine metabolism not influenced by level of carbohydrate intake. ( 3691321 )
1987
39
Antipyrine metabolism in cultured rat hepatocytes. ( 3632725 )
1987
40
Comparison of effects of ozone, cadmium chloride and carbon tetrachloride on [14C]antipyrine metabolism in conscious rats. ( 3624772 )
1987
41
Inhibition and induction of metronidazole and antipyrine metabolism. ( 3582467 )
1987
42
Antipyrine metabolism in acute hepatic porphyria in relapse and remission. ( 3567053 )
1987
43
Antipyrine metabolism in the Venda. ( 3557469 )
1987
44
Studies on in vitro antipyrine metabolism by 13C,15N double labeled method. ( 3298908 )
1987
45
Inhibition of antipyrine metabolism by interferon. ( 3790409 )
1986
46
Dynamic interactions among host factors that influence antipyrine metabolism: implications for the design and interpretation of studies on ethnic pharmacokinetic variations. ( 3523515 )
1986
47
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator. ( 4087137 )
1985
48
Antipyrine metabolism during hepatic regeneration in the rat. ( 4058271 )
1985
49
Effect of hypoxia and pregnancy on antipyrine metabolism in isolated perfused rat livers. ( 4032283 )
1985
50
Antipyrine metabolism in African villagers. ( 4018817 )
1985

Variations for Antipyrine Metabolism

Expression for Antipyrine Metabolism

Search GEO for disease gene expression data for Antipyrine Metabolism.

Pathways for Antipyrine Metabolism

Pathways related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 ALB F2
2 10.27 ALB F2

GO Terms for Antipyrine Metabolism

Cellular components related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 8.96 ALB F2
2 blood microparticle GO:0072562 8.62 ALB F2

Biological processes related to Antipyrine Metabolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.62 ALB F2

Sources for Antipyrine Metabolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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