Aliases & Classifications for Anuria

MalaCards integrated aliases for Anuria:

Name: Anuria 12 54 44 15 17 70
Suppression of Urinary Secretion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2983
MeSH 44 D001002
NCIt 50 C114699
SNOMED-CT 67 139460001
UMLS 70 C0003460

Summaries for Anuria

MalaCards based summary : Anuria, also known as suppression of urinary secretion, is related to renal tubular dysgenesis and uremia, and has symptoms including oliguria and anuria, polyuria and suppressed urine secretion. An important gene associated with Anuria is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are AGE-RAGE signaling pathway in diabetic complications and Renin secretion. The drugs carbamide peroxide and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and cortex, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 73 Anuria is nonpassage of urine, in practice is defined as passage of less than 100 milliliters of urine... more...

Related Diseases for Anuria

Diseases related to Anuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 538)
# Related Disease Score Top Affiliating Genes
1 renal tubular dysgenesis 32.3 REN AGTR1 AGT ACE
2 uremia 30.9 REN CRP ALB ACE
3 glomerulonephritis 30.6 LCN2 ALB AGTR1 ACE
4 renal artery obstruction 30.6 REN ACE
5 hydronephrosis 30.5 REN HAVCR1 CRP ALB
6 pyelonephritis 30.4 LCN2 CRP ALB ACE
7 proteinuria, chronic benign 30.4 REN ALB AGTR1 ACE
8 kidney cortex necrosis 30.4 F2 ADAMTS13
9 oligohydramnios 30.3 REN AGTR1 AGT ACE
10 renal hypodysplasia/aplasia 1 30.2 REN AGTR1 AGT ACE
11 hyperuricemia 30.2 REN CRP ALB
12 renovascular hypertension 30.2 REN LCN2 AGTR1 ACE
13 urinary tract infection 30.1 LCN2 CRP ACE
14 gastroenteritis 30.1 REN CRP ALB
15 renal tuberculosis 30.1 REN CRP
16 acute pyelonephritis 30.0 LCN2 CRP ALB ACE
17 posterior urethral valves 30.0 AGTR1 AGT ACE
18 malignant hypertension 30.0 REN AGTR1 AGT ADAMTS13 ACE
19 blackwater fever 30.0 MB HP
20 eclampsia 30.0 REN F2 ALB AGT ACE
21 urinary tract obstruction 30.0 REN LCN2 HAVCR1 CRP ALB ACE
22 fibromuscular dysplasia 29.9 REN AGTR1 AGT ACE
23 paralytic ileus 29.8 F2 CRP ALB
24 congenital anomalies of kidney and urinary tract 2 29.7 REN LCN2 HAVCR1
25 gas gangrene 29.7 PIK3C2A MB CRP
26 cholangitis, primary sclerosing 29.6 F2 CRP ALB
27 obstructive jaundice 29.6 REN F2 CRP ALB
28 pneumonia 29.6 PIK3C2A CRP ALB ACE
29 sickle cell anemia 29.6 F2 CRP ALB ACE
30 focal segmental glomerulosclerosis 29.6 LCN2 ALB AGTR1 AGT ACE
31 sclerosing cholangitis 29.6 HP F2 ALB
32 hemoglobinuria 29.5 MB HP F2
33 hemolytic-uremic syndrome 29.5 HP F3 F2 ADAMTS13
34 tetanus 29.5 MB CRP ALB
35 thrombotic microangiopathy 29.4 HP F3 ADAMTS13
36 endocarditis 29.4 PIK3C2A F2 CRP ALB
37 purpura 29.4 F3 F2 CRP ADAMTS13 ACE
38 pulmonary edema 29.3 REN PIK3C2A HP F2 CRP AGTR1
39 mitral valve stenosis 29.2 REN F3 F2 CRP ACE
40 interstitial nephritis 29.2 REN HAVCR1 CRP ALB AGTR1 AGT
41 renal artery disease 29.2 REN CST3 ALB AGTR1 AGT ACE
42 thrombotic thrombocytopenic purpura 29.2 HP F3 ADAMTS13
43 pyuria 29.1 LCN2 HAVCR1 F2 CRP ALB
44 aortic aneurysm, familial abdominal, 1 29.1 REN LCN2 CST3 CRP ALB AGTR1
45 hemolytic uremic syndrome, atypical 1 29.0 HP F3 ALB ADAMTS13
46 hepatorenal syndrome 29.0 REN LCN2 F2 CST3 ALB ACE
47 pulmonary embolism 28.9 MB F3 F2 CRP ALB ACE
48 polycystic kidney disease 28.9 REN LCN2 CST3 ALB AGTR1 AGT
49 aortic valve insufficiency 28.8 REN F3 F2 CRP ALB ACE
50 acute kidney failure 28.8 REN PIK3C2A MB LCN2 HP HAVCR1

Graphical network of the top 20 diseases related to Anuria:



Diseases related to Anuria

Symptoms & Phenotypes for Anuria

UMLS symptoms related to Anuria:


oliguria and anuria; polyuria; suppressed urine secretion; kidney problem

GenomeRNAi Phenotypes related to Anuria according to GeneCards Suite gene sharing:

26 (show all 25)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.78 HSD11B2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-104 9.78 HSD11B2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-111 9.78 CST3
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.78 CRP HSD11B2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.78 ADAMTS13
6 Increased shRNA abundance (Z-score > 2) GR00366-A-134 9.78 CST3
7 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.78 ADAMTS13
8 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.78 CRP HSD11B2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-148 9.78 CRP
10 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.78 CRP HSD11B2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-174 9.78 CST3
12 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.78 ADAMTS13
13 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.78 HSD11B2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.78 CST3
15 Increased shRNA abundance (Z-score > 2) GR00366-A-203 9.78 CST3
16 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.78 CST3
17 Increased shRNA abundance (Z-score > 2) GR00366-A-26 9.78 CST3
18 Increased shRNA abundance (Z-score > 2) GR00366-A-34 9.78 CST3
19 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.78 HSD11B2
20 Increased shRNA abundance (Z-score > 2) GR00366-A-51 9.78 HSD11B2
21 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.78 HSD11B2
22 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.78 CRP HSD11B2
23 Increased shRNA abundance (Z-score > 2) GR00366-A-76 9.78 CST3
24 Increased shRNA abundance (Z-score > 2) GR00366-A-89 9.78 ADAMTS13
25 Increased shRNA abundance (Z-score > 2) GR00366-A-97 9.78 ADAMTS13

MGI Mouse Phenotypes related to Anuria:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.28 ACE AGT AGTR1 ALB CRP CST3
2 homeostasis/metabolism MP:0005376 10.27 ACE ADAMTS13 AGT AGTR1 ALB CRP
3 mortality/aging MP:0010768 10.13 ACE ADAMTS13 AGT AGTR1 ALB CST3
4 immune system MP:0005387 10.1 ACE ADAMTS13 AGT AGTR1 ALB CRP
5 muscle MP:0005369 9.81 AGT ALB CST3 F2 F3 HSD11B2
6 neoplasm MP:0002006 9.43 ACE ALB CST3 F3 HP HSD11B2
7 renal/urinary system MP:0005367 9.32 ACE AGT AGTR1 ALB HP HSD11B2

Drugs & Therapeutics for Anuria

Drugs for Anuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
carbamide peroxide Approved 124-43-6
2 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Controlled Multi-Center Trial of the Early Application of CRRT in Patients With Severe Sepsis or Septic Shock Unknown status NCT00837057 Phase 4
2 Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria Unknown status NCT02139059
3 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage in Children With Obstructive Anuria and Acute Renal Failure Due to Ureteral Calculi: a Prospective, Randomized Study Completed NCT02055430
4 The Artificial Kidney Initiation in Kidney Injury 2 A Multi-Centre, Randomized, Controlled Trial Completed NCT03396757
5 Hemodialysis Frequency and the Calcification Propensity of Serum Completed NCT01975025
6 Acute Kidney Injury in Patients With Acute Respiratory Distress Syndrome: Incidence, Risk Factors and Its Impact on the Outcome Completed NCT04154007
7 Perioperative Relevance of Intraoperative Anuric Episodes Within a Goal-directed Haemodynamic Algorithm in Patients Undergoing Laparotomy Due to Epithelial Ovarian Cancer Withdrawn NCT01703442

Search NIH Clinical Center for Anuria

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Mannitol
Mannitol hexanitrate
MANNITOL PWDR

Cochrane evidence based reviews: anuria

Genetic Tests for Anuria

Anatomical Context for Anuria

MalaCards organs/tissues related to Anuria:

40
Kidney, Heart, Cortex, Uterus, Bone, Liver, Bone Marrow

Publications for Anuria

Articles related to Anuria:

(show top 50) (show all 3250)
# Title Authors PMID Year
1
Rhabdomyolysis following recent severe coxsackie virus infection in patient with chronic renal failure: one case report and a review of the literature. 61 54
16526325 2006
2
[A case of rhabdomyolysis associated with Salmonella encephalopathy]. 61 54
12440101 2002
3
[Acute renal insufficiency caused by burn injury]. 54 61
9102856 1996
4
[Experience with the use of plasmapheresis in the combined treatment of children with the crush syndrome]. 61 54
2333628 1990
5
Severe acute kidney injury following Sri Lankan Hypnale spp. envenoming is associated with thrombotic microangiopathy. 61
32870056 2021
6
COVID-19 presented as acute kidney injury with secondary myocardial damage. 61
33647554 2021
7
Takotsubo syndrome and pheochromocytoma: an insidious combination. 61
33691391 2021
8
Atypical hemolytic uremic syndrome and acute tubular necrosis induced by complement factor B gene (CFB) mutation: A case report. 61
33725982 2021
9
Successful High-dose Chemotherapy in Combination With Autologous Peripheral Blood Stem Cell Transplantation in an Anuric Child With Neuroblastoma. 61
33625080 2021
10
Spontaneous urinary bladder perforation: An unusual presentation of well-differentiated papillary peritoneum mesothelioma. 61
33779398 2021
11
Reflex anuria causing acute kidney injury following myomectomy: A case report. 61
33522051 2021
12
[TAFRO syndrome and cutaneous necrotizing vasculitis]. 61
33218790 2021
13
Renal failure and hepatitis following ingestion of raw grass carp gallbladder: A case report. 61
33585643 2021
14
Snake bite associated with acute kidney injury. 61
33559706 2021
15
111In-Labeled White Blood Cell Uptake in the Urinary Bladder in Occult Urinary Tract Infection. 61
33315678 2021
16
Crystalglobulinemia causing cutaneous vasculopathy and acute nephropathy in a kidney transplant patient. 61
33565232 2021
17
Tumor Embolism as a Cause of Renal Artery Occlusion and Acute Kidney Injury Diagnosed and Treated with Endovascular Intervention in a Patient with Mediastinal Undifferentiated Sarcoma. 61
33456039 2021
18
[Acute renal failure of the donor in encephalic death: A real contraindication to kidney transplantation?] 61
33478867 2021
19
Rhabdomyolysis with acute anuria renal failure caused by surgical injection-induced tetanus in an adult. 61
33479088 2021
20
Unexpected success in early post-transplantation renal vein thrombosis: A case report and literature review. 61
33633926 2021
21
Effect of Endoscopic Ureteral Stone Treatment on Kidney Function. 61
33633912 2021
22
Daptomycin Pharmacokinetics in Adolescents Undergoing Hemodialysis and Peritoneal Dialysis: A Case Series With Pharmacokinetic Modeling. 61
33603575 2021
23
Net ultrafiltration prescription survey in Europe. 61
33256635 2020
24
Successful treatment of acute circulatory failure of unknown cause using critical ultrasound-guided reverse fluid resuscitation: A case report. 61
33371091 2020
25
Factors Associated With Postoperative Voiding Dysfunction Post Renal Transplantation. 61
32593439 2020
26
Effect of losartan on the recoverability of renal function in anuric and oliguric patients with a solitary obstructed kidney: a double-blind randomized placebo-controlled trial. 61
32648662 2020
27
Effects of exercise on residual renal function in patients undergoing peritoneal dialysis: A post-hoc analysis of a randomized controlled trial. 61
31997526 2020
28
Case - Reflex anuria: A rare complication of retrograde pyelography. 61
33382376 2020
29
Anuria in neonatal intensive care: Answers. 61
32451731 2020
30
Anuria in neonatal intensive care: Questions. 61
32451730 2020
31
Rare renal pathologic manifestation of antineutrophil cytoplasmic antibodies associated vasculitis as suppurative interstitial nephritis: A case report and review of the literature. 61
33565458 2020
32
Postdiarrheal hemolytic uremic syndrome in Egyptian children: An 11-year single-center experience. 61
33565450 2020
33
Multi-parasite infection in an immigrant from Ghana: potential for new epidemic foci. 61
33296350 2020
34
Autosomal Recessive Renal Tubular Dysgenesis Caused by a Founder Mutation of Angiotensinogen. 61
33163725 2020
35
Spontaneous bladder rupture: Laparoscopic management of rare complications after nontraumatic vaginal delivery. 61
33102075 2020
36
Multiples deep abscesses: A rare complications of bricker ileal conduit urinary diversion after bilateral stenosis of the uretero-ileal anastomosis. 61
33102097 2020
37
Concurrent Thoracic Endovascular Aortic Repair and Liver Transplant: Multidisciplinary Management of Multiple Posttraumatic Lesions. 61
33227463 2020
38
A longitudinal analysis of the relationship between serum uric acid and residual renal function loss in peritoneal dialysis patients. 61
32401146 2020
39
Vajra Bhasma, Ayurvedic medicine: a rare and unusual cause of Lyell's syndrome and its successful management. 61
33127708 2020
40
Clear Cell carcinoma of the urinary bladder, A case report: Surgical and oncological management. 61
33016051 2020
41
'Full prosthetic jacket': external stenting of the renal vein. 61
30973079 2020
42
A Needle in the Haystack: A Rare Case of Spontaneous Tumor Lysis in Newly Diagnosed Chronic Lymphocytic Leukemia Unmasked by Acute Renal Failure. 61
33274154 2020
43
Drug rash with eosinophilia and systemic symptoms and severe renal injury induced by proton pump inhibitor therapy: A case report. 61
33080685 2020
44
Urinary neutrophil gelatinase-associated lipocalin determines short-term mortality and type of acute kidney injury in cirrhosis. 61
33102772 2020
45
Ultrasonography and Surgical Treatment of an Unusual Case of Urethral Calculus in an Arabian Horse. 61
32797778 2020
46
Novel risk models to predict acute kidney disease and its outcomes in a Chinese hospitalized population with acute kidney injury. 61
32973230 2020
47
Delayed type III hypersensitivity reaction with acute kidney injury in two dogs following administration of concentrated human albumin during treatment for hypoalbuminemia secondary to septic peritonitis. 61
32652787 2020
48
Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study. 61
32677736 2020
49
Staphylococcal toxic shock syndrome in a child with interleukin-17 inhibitor treatment for psoriasis. 61
32533569 2020
50
Emphysematous Pyelonephritis in a Diabetic Patient with Remarkable Radiological Findings and Excellent Outcome without Surgical Intervention or Drainage. 61
32950996 2020

Variations for Anuria

Expression for Anuria

Search GEO for disease gene expression data for Anuria.

Pathways for Anuria

Pathways related to Anuria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 F3 AGTR1 AGT
2 11.1 REN AGTR1 AGT ACE
3
Show member pathways
10.92 REN NR3C2 AGTR1 AGT ACE

GO Terms for Anuria

Cellular components related to Anuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.91 PIK3C2A MB LCN2 HP F2 CST3
2 extracellular region GO:0005576 9.7 REN LCN2 HP F3 F2 CST3
3 endoplasmic reticulum lumen GO:0005788 9.62 F2 CST3 ALB ADAMTS13
4 blood microparticle GO:0072562 9.46 HP F2 ALB AGT
5 extracellular space GO:0005615 9.36 REN LCN2 HP F3 F2 CST3

Biological processes related to Anuria according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.97 REN HP F2 ADAMTS13 ACE
2 kidney development GO:0001822 9.71 REN AGTR1 AGT ACE
3 regulation of blood pressure GO:0008217 9.7 REN AGT ACE
4 hemostasis GO:0007599 9.67 F3 F2 ADAMTS13
5 acute-phase response GO:0006953 9.63 HP F2 CRP
6 peptide catabolic process GO:0043171 9.58 ADAMTS13 ACE
7 positive regulation of cellular protein metabolic process GO:0032270 9.58 AGTR1 AGT
8 amyloid-beta metabolic process GO:0050435 9.56 REN ACE
9 angiotensin maturation GO:0002003 9.55 REN ACE
10 positive regulation of cholesterol esterification GO:0010873 9.54 AGTR1 AGT
11 positive regulation of reactive oxygen species metabolic process GO:2000379 9.54 F2 AGTR1 AGT
12 positive regulation of NAD(P)H oxidase activity GO:0033864 9.51 AGTR1 AGT
13 regulation of renal sodium excretion GO:0035813 9.48 AGTR1 AGT
14 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.43 AGTR1 AGT
15 regulation of vasoconstriction GO:0019229 9.33 AGTR1 AGT ACE
16 regulation of renal output by angiotensin GO:0002019 9.32 AGT ACE
17 regulation of blood volume by renin-angiotensin GO:0002016 9.26 REN AGT
18 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.13 AGTR1 AGT ACE
19 renin-angiotensin regulation of aldosterone production GO:0002018 8.8 REN AGTR1 AGT

Molecular functions related to Anuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 9.43 LCN2 F3 CST3
2 endopeptidase activity GO:0004175 9.33 REN ADAMTS13 ACE
3 enterobactin binding GO:1903981 8.96 LCN2 ALB
4 bradykinin receptor binding GO:0031711 8.62 AGTR1 ACE

Sources for Anuria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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