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MCID: ANR004
MIFTS: 43

Anuria

Categories: Nephrological diseases
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Aliases & Classifications for Anuria

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MalaCards integrated aliases for Anuria:

Name: Anuria 11 53 43 14 16 71 75
Suppression of Urinary Secretion 11

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 11 DOID:2983
MeSH 43 D001002
NCIt 49 C114699
SNOMED-CT 68 139460001
UMLS 71 C0003460
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Summaries for Anuria

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MalaCards based summary: Anuria, also known as suppression of urinary secretion, is related to renal tubular dysgenesis and uremia, and has symptoms including oliguria and anuria, polyuria and suppressed urine secretion. An important gene associated with Anuria is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and ACE Inhibitor Pathway, Pharmacodynamics. The drug Anesthetics has been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism

Wikipedia: 75 Anuria is nonpassage of urine, in practice is defined as passage of less than 100 milliliters of urine... more...
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Related Diseases for Anuria

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Diseases related to Anuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 656)
# Related Disease Score Top Affiliating Genes
1 renal tubular dysgenesis 32.2 REN AGTR1 AGT ACE
2 uremia 30.9 REN CRP ALB ACE
3 ureterolithiasis 30.6 F2 CRP ALB
4 renal artery obstruction 30.5 REN ACE
5 hydronephrosis 30.5 REN LCN2 HAVCR1 CRP ALB
6 pyelonephritis 30.5 LCN2 CRP ALB ACE
7 renal artery atheroma 30.3 REN CST3 ALB AGTR1 ACE
8 glomerulonephritis 30.3 REN LCN2 CRP ALB AGTR1 ACE
9 appendicitis 30.2 LCN2 CRP ALB
10 potter's syndrome 30.1 REN AGTR1 AGT ACE
11 henoch-schoenlein purpura 30.1 CRP CFHR2 ALB ACE
12 gastroenteritis 30.0 REN CRP ALB
13 congenital anomalies of kidney and urinary tract 2 30.0 REN LCN2 HAVCR1
14 obstructive jaundice 30.0 F2 CRP ALB
15 gastric dilatation 30.0 CRP ALB
16 renal tuberculosis 30.0 REN CRP ALB
17 oligohydramnios 29.9 REN CRP ALB AGTR1 AGT ACE
18 acute pyelonephritis 29.9 LCN2 HAVCR1 CRP ALB
19 blackwater fever 29.9 MB HP
20 renovascular hypertension 29.9 REN NR3C2 ALB AGTR1 AGT ACE
21 fibromuscular dysplasia 29.9 REN AGTR1 AGT ACE
22 purpura 29.9 F3 F2 CRP ADAMTS13
23 placental abruption 29.8 F3 F2 CFHR2
24 autonomic nervous system disease 29.8 REN CRP ALB ACE
25 hyperuricemia 29.8 REN LCN2 HAVCR1 CRP ALB
26 urinary tract obstruction 29.8 REN LCN2 HAVCR1 CST3 CRP ALB
27 thrombocytopenic purpura, autoimmune 29.8 F3 F2 ADAMTS13
28 focal segmental glomerulosclerosis 29.7 REN CFHR2 ALB AGTR1 AGT ACE
29 aortic dissection 29.7 CRP ALB ACE
30 schistosomiasis 29.7 F2 CRP ALB
31 eclampsia 29.7 REN F3 F2 ALB AGT ACE
32 hemolytic-uremic syndrome 29.6 HP F3 F2 CFHR2 ADAMTS13
33 methemoglobinemia 29.6 MB HP ALB
34 babesiosis 29.6 HP CRP ALB
35 malignant hypertension 29.6 REN HP CFHR2 AGTR1 ADAMTS13 ACE
36 limb ischemia 29.6 F3 CRP ALB ACE
37 afibrinogenemia, congenital 29.6 F3 F2 CFHR2
38 congestive heart failure 29.5 REN NR3C2 ALB AGTR1 AGT ACE
39 iga glomerulonephritis 29.5 REN CFHR2 ALB AGTR1 AGT ACE
40 aortic valve disease 1 29.5 REN F2 CRP AGTR1 ACE
41 hemoglobinuria 29.5 MB HP F2
42 kidney cortex necrosis 29.4 HP F3 F2 CFHR2 ADAMTS13
43 paralytic ileus 29.4 F3 F2 CRP ALB
44 hemorrhagic disease 29.4 F3 F2 CRP ALB ADAMTS13
45 kidney papillary necrosis 29.4 REN HAVCR1 F3 CST3 ALB ACE
46 sclerosing cholangitis 29.3 HP F2 CRP ALB
47 hypersensitivity vasculitis 29.3 REN F2 CRP CFHR2 ALB ACE
48 peripheral nervous system disease 29.3 REN F3 CRP ALB ACE
49 pulmonary embolism 29.3 MB F3 F2 CRP ALB ACE
50 hypokalemia 29.3 REN PIK3C2A NR3C2 MB HSD11B2 ALB

Graphical network of the top 20 diseases related to Anuria:



Diseases related to Anuria
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Symptoms & Phenotypes for Anuria

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UMLS symptoms related to Anuria:


oliguria and anuria; polyuria; suppressed urine secretion; kidney problem

GenomeRNAi Phenotypes related to Anuria according to GeneCards Suite gene sharing:

25 (show all 27)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.19 ACE ADAMTS13 AGT AGTR1 ALB CFHR2
2 no effect GR00402-S-2 10.19 ACE ADAMTS13 AGT AGTR1 ALB CFHR2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-101 10.12 HSD11B2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-104 10.12 HSD11B2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-111 10.12 CST3
6 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.12 CRP HSD11B2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-13 10.12 ADAMTS13
8 Increased shRNA abundance (Z-score > 2) GR00366-A-134 10.12 CST3
9 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.12 ADAMTS13
10 Increased shRNA abundance (Z-score > 2) GR00366-A-147 10.12 CRP HSD11B2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-148 10.12 CRP
12 Increased shRNA abundance (Z-score > 2) GR00366-A-161 10.12 CRP HSD11B2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-174 10.12 CST3
14 Increased shRNA abundance (Z-score > 2) GR00366-A-178 10.12 ADAMTS13
15 Increased shRNA abundance (Z-score > 2) GR00366-A-191 10.12 HSD11B2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-195 10.12 CST3
17 Increased shRNA abundance (Z-score > 2) GR00366-A-203 10.12 CST3
18 Increased shRNA abundance (Z-score > 2) GR00366-A-214 10.12 CST3
19 Increased shRNA abundance (Z-score > 2) GR00366-A-26 10.12 CST3
20 Increased shRNA abundance (Z-score > 2) GR00366-A-34 10.12 CST3
21 Increased shRNA abundance (Z-score > 2) GR00366-A-50 10.12 HSD11B2
22 Increased shRNA abundance (Z-score > 2) GR00366-A-51 10.12 HSD11B2
23 Increased shRNA abundance (Z-score > 2) GR00366-A-57 10.12 HSD11B2
24 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.12 CRP HSD11B2
25 Increased shRNA abundance (Z-score > 2) GR00366-A-76 10.12 CST3
26 Increased shRNA abundance (Z-score > 2) GR00366-A-89 10.12 ADAMTS13
27 Increased shRNA abundance (Z-score > 2) GR00366-A-97 10.12 ADAMTS13

MGI Mouse Phenotypes related to Anuria:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.31 ACE ADAMTS13 AGT AGTR1 ALB CRP
2 cardiovascular system MP:0005385 10.2 ACE AGT AGTR1 ALB CRP CST3
3 renal/urinary system MP:0005367 10.16 ACE AGT AGTR1 ALB HP HSD11B2
4 cellular MP:0005384 10.15 ACE ALB CST3 F2 F3 HP
5 muscle MP:0005369 10.09 AGT ALB CST3 F2 F3 HSD11B2
6 behavior/neurological MP:0005386 10.03 ACE AGT AGTR1 F2 F3 HAVCR1
7 immune system MP:0005387 9.97 ACE ADAMTS13 AGT AGTR1 ALB CRP
8 hematopoietic system MP:0005397 9.73 ACE ADAMTS13 AGTR1 F2 F3 HAVCR1
9 mortality/aging MP:0010768 9.53 ACE ADAMTS13 AGT AGTR1 ALB CST3
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Drugs & Therapeutics for Anuria

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Drugs for Anuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
2 Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria Unknown status NCT02139059
3 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage in Children With Obstructive Anuria and Acute Renal Failure Due to Ureteral Calculi: a Prospective, Randomized Study Completed NCT02055430
4 Hemodialysis Frequency and the Calcification Propensity of Serum Completed NCT01975025
5 Prospective Study on the Effects of the Intermittent Pneumoperitoneum (IPP) Work Break Scheme on Surgeons and Patients. Completed NCT01009372
6 Primary Versus Deferred Ureteroscopy for Management of Calculus Anuria in Children: A Prospective Randomized Study Recruiting NCT04980079
7 Perioperative Relevance of Intraoperative Anuric Episodes Within a Goal-directed Haemodynamic Algorithm in Patients Undergoing Laparotomy Due to Epithelial Ovarian Cancer Withdrawn NCT01703442

Search NIH Clinical Center for Anuria

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Mannitol
Mannitol hexanitrate
MANNITOL PWDR

Cochrane evidence based reviews: anuria

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Genetic Tests for Anuria

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Anatomical Context for Anuria

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Organs/tissues related to Anuria:

MalaCards : Kidney, Heart, Liver, Uterus, Bone Marrow, Cervix, Prostate
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Publications for Anuria

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Articles related to Anuria:

(show top 50) (show all 3362)
# Title Authors PMID Year
1
Rhabdomyolysis following recent severe coxsackie virus infection in patient with chronic renal failure: one case report and a review of the literature. 53 62
16526325 2006
2
[A case of rhabdomyolysis associated with Salmonella encephalopathy]. 53 62
12440101 2002
3
[Acute renal insufficiency caused by burn injury]. 53 62
9102856 1996
4
[Experience with the use of plasmapheresis in the combined treatment of children with the crush syndrome]. 53 62
2333628 1990
5
An Encrusted Ureteral Stent Removed by Open Surgery in a Solitary Pelvic Ectopic Kidney (PEK) Patient Presented with Anuria and Renal Dysfunction: A Case Report. 62
32135560 2022
6
Primary versus deferred ureteroscopy for the management of obstructive anuria secondary to ureteric urolithiasis in children: a prospective randomized study. 62
36459265 2022
7
Clinical characteristics and outcomes of antibiotic-associated encephalopathy in patients with end-stage kidney disease. 62
36259485 2022
8
Contribution of Serial Focused High-Resolution Renal Ultrasound in the Management of a Neonate in Acute Renal Failure. 62
36451964 2022
9
Anti-glomerular basement membrane diseases and thrombotic microangiopathy treated with rituximab. 62
36420905 2022
10
Comparative polymyxin B pharmacokinetics in critically ill patients with renal insufficiency and in continuous veno-venous hemodialysis. 62
36378296 2022
11
Target attainment and pharmacokinetics of cefotaxime in critically ill patients undergoing continuous kidney replacement therapy. 62
36210582 2022
12
Should a Living Donor Renal Graft be Removed Due To Prolonged Delayed Function? A Case Report. 62
36374795 2022
13
Single-dose intravesical amikacin instillation for pyocystis in a patient with autonomic dysreflexia: A case report. 62
33983103 2022
14
Severe delayed graft function in a living-related kidney transplant recipient due to combination of alloimmunity, autoimmunity, and heterologous immunity: A case report. 62
36324262 2022
15
Bilateral Ureterovesical Junction Obstruction Resulting in Anuria in a 3-Week-Old Infant. 62
35623500 2022
16
Bilateral renal subcapsular hematoma caused by polyarteritis nodosa: a case report. 62
35171449 2022
17
Spontaneous urinary bladder perforation: An unusual presentation of well-differentiated papillary peritoneum mesothelioma. 62
33779398 2022
18
A Child with Abdominal Pain and Anuria. 62
35866320 2022
19
Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report. 62
36250482 2022
20
Bilateral Renal Artery Thrombosis: A Case of Successful Kidney Recovery After Prolonged Anuria. 62
36381786 2022
21
A 66-Year-Old Woman with Achondroplasia and Quadriparesis with an Ovarian Cyst Erroneously Diagnosed as Urinary Retention by an Automated Bladder Scan. 62
36299173 2022
22
A unique case of anti-GBM disease with concomitant anti-PLA2R positivity. 62
36271343 2022
23
Nationwide observational study of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the Czech Republic. 62
35987943 2022
24
Solitary kidney functional damage due to caesarean ureteric injury monitored for 2 years after acute management: A case report. 62
36035238 2022
25
Unexpected difficult airway due to severe upper tracheal distortion: A case report. 62
36159427 2022
26
Page phenomenon in a transplanted kidney: is it salvageable? 62
36162963 2022
27
Anti-GBM Disease after Oxford-AstraZeneca ChAdOx1 nCoV-19 Vaccination: A Report of Two Cases. 62
36465571 2022
28
Milk-Alkali Syndrome: How Electronic Medical Record Open Notes Helped to Rule Out Cancer. 62
36056538 2022
29
Comparative Genomics of Shiga Toxin-Producing Escherichia coli Strains Isolated from Pediatric Patients with and without Hemolytic Uremic Syndrome from 2000 to 2016 in Finland. 62
35730965 2022
30
Design and Protocol of the Renal Anhydramnios Fetal Therapy (RAFT) Trial. 62
35918190 2022
31
Successful renal recovery from multiple myeloma-associated crystalline light chain cast nephropathy and accompanying acute kidney injury with early use of bortezomib-based therapy: a case report and literature review. 62
35854043 2022
32
Emergency upper urinary tract decompression: double-J stent or nephrostomy? A European YAU/ESUT/EULIS/BSIR survey among urologists and radiologists. 62
35286423 2022
33
Successful weight reduction of over 70 kg under hemodialysis and renal function recovery after 87 days of anuria in a patient with dilated cardiomyopathy. 62
35923529 2022
34
Increased level of free-circulating MtDNA in maintenance hemodialysis patients: Possible role in systemic inflammation. 62
35708020 2022
35
Prognostic significance of risk factors and biomarkers in patients hospitalized for cardiorenal syndromes: A pilot study. 62
35733316 2022
36
Emergency open drainage of massive hemoperitoneum and early stage left hepatectomy for abdominal compartment syndrome due to hepatocellular carcinoma rupture: a case report. 62
35731449 2022
37
Constructing a continuous hemodiafiltration-type circulatory model of acute kidney injury in pigs. 62
35247221 2022
38
Treatment of Severe Renal Artery Stenosis with Acute Kidney Injury Requiring Hemodialysis by Percutaneous Transluminal Renal Angioplasty and Stent Implantation. 62
35288233 2022
39
Phosphatidylethanol (PEth) for Monitoring Sobriety in Liver Transplant Candidates: Preliminary Results of Differences Between Alcohol-Related and Non-Alcohol-Related Cirrhosis Candidates. 62
35668618 2022
40
Acute renal failure and bladder tumors, about 106 cases. 62
35181289 2022
41
[Prepubic urethrostomy in a Wiesenauer minipig with urolithiasis]. 62
35790159 2022
42
Acute bilateral ureteropelvic junction obstruction as a rare cause of hypertensive crisis: a case report. 62
35606828 2022
43
Expanding the clinical spectrum of autosomal-recessive renal tubular dysgenesis: Two siblings with neonatal survival and review of the literature. 62
35286024 2022
44
Metformin-associated lactic acidosis exacerbated by acute kidney injury in an overseas traveler. 62
34837633 2022
45
Continuous Monitoring of Intra-abdominal Pressure in Severe Acute Pancreatitis Leads to Early Detection of Abdominal Compartment Syndrome: A Case Report. 62
35509753 2022
46
Delayed Graft Function Complicated by Anuria in a Kidney Transplant Patient. 62
35721624 2022
47
Bilateral Renal Mucor Mycosis Presenting as Anuria in a Covid 19 Recovered Patient: A Case Report and Review of Literature. 62
34968570 2022
48
Obstructive oligo-anuria revealing pelvic gynecological cancers, analysis of a series of 102 cases. 62
35198181 2022
49
Foley catheter erosion through bladder wall causing intraperitoneal bladder injury: a case report. 62
35280051 2022
50
Acute kidney injury in dogs: Etiology, clinical and clinicopathologic findings, prognostic markers, and outcome. 62
35103347 2022
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Variations for Anuria

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Expression for Anuria

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Search GEO for disease gene expression data for Anuria.
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Pathways for Anuria

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Pathways related to Anuria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 66
Show member pathways
 11.62 IGFBP7 F2 CST3 ALB
2
ACE Inhibitor Pathway, Pharmacodynamics 60
Show member pathways
 11.08 REN NR3C2 AGTR1 AGT ACE
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GO Terms for Anuria

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Cellular components related to Anuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 10.03 ACE ADAMTS13 AGT ALB CFHR2 CRP
2 endoplasmic reticulum lumen GO:0005788 9.96 IGFBP7 F2 CST3 ALB ADAMTS13
3 blood microparticle GO:0072562 9.76 HP F2 ALB AGT
4 extracellular space GO:0005615 9.74 REN LCN2 IGFBP7 HP F3 F2

Biological processes related to Anuria according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 10.13 REN AGTR1 AGT ACE
2 acute-phase response GO:0006953 9.99 HP F2 CRP
3 positive regulation of reactive oxygen species metabolic process GO:2000379 9.95 F2 AGTR1 AGT
4 positive regulation of NAD(P)H oxidase activity GO:0033864 9.84 AGTR1 AGT
5 blood vessel diameter maintenance GO:0097746 9.83 ACE AGT AGTR1
6 regulation of renal sodium excretion GO:0035813 9.8 AGTR1 AGT
7 regulation of vasoconstriction GO:0019229 9.8 AGTR1 AGT ACE
8 maintenance of blood vessel diameter homeostasis by renin-angiotensin GO:0002034 9.71 AGTR1 AGT
9 regulation of renal output by angiotensin GO:0002019 9.67 AGT ACE
10 vasoconstriction GO:0042310 9.65 CRP AGT ACE
11 hemostasis GO:0007599 9.63 F3 F2 ADAMTS13
12 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.35 AGTR1 AGT ACE
13 regulation of blood volume by renin-angiotensin GO:0002016 9.33 REN AGT
14 renin-angiotensin regulation of aldosterone production GO:0002018 9.1 REN AGTR1 AGT

Molecular functions related to Anuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enterobactin binding GO:1903981 9.26 LCN2 ALB
2 bradykinin receptor binding GO:0031711 8.92 AGTR1 ACE
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Sources for Anuria

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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