MCID: ANS010
MIFTS: 24

Anus Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Anus Adenocarcinoma

MalaCards integrated aliases for Anus Adenocarcinoma:

Name: Anus Adenocarcinoma 12 15
Adenocarcinoma of the Anus 12
Adenocarcinoma of Anus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3447
NCIt 50 C5600
SNOMED-CT 67 423607006
UMLS 70 C1332257

Summaries for Anus Adenocarcinoma

Disease Ontology : 12 An anal carcinoma that originating in the cortex of the adrenal gland and derives from epithelial cells of glandular origin.

MalaCards based summary : Anus Adenocarcinoma, also known as adenocarcinoma of the anus, is related to anal canal adenocarcinoma and anal colloid adenocarcinoma. An important gene associated with Anus Adenocarcinoma is CD320 (CD320 Molecule), and among its related pathways/superpathways are Diseases of metabolism and Cobalamin (Cbl, vitamin B12) transport and metabolism. Affiliated tissues include cortex, adrenal gland and appendix.

Related Diseases for Anus Adenocarcinoma

Diseases related to Anus Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 anal canal adenocarcinoma 29.3 MUC5AC KRT7 CDX2
2 anal colloid adenocarcinoma 11.2
3 spleen angiosarcoma 10.1 TCN2 CD320
4 vitamin metabolic disorder 10.0 TCN2 CD320
5 vitamin b12 deficiency 10.0 TCN2 CD320
6 rare tumor 10.0
7 malignant exocrine pancreas neoplasm 10.0 MUC5AC CDX2
8 omphalocele 10.0 TCN2 CD320
9 bile reflux 9.9 MUC5AC CDX2
10 microinvasive gastric cancer 9.9 MUC5AC CDX2
11 bile duct cystadenocarcinoma 9.9 MUC5AC KRT7
12 cystadenocarcinoma 9.9 MUC5AC KRT7
13 cystadenoma 9.9 MUC5AC KRT7
14 biliary papillomatosis 9.9 MUC5AC KRT7
15 bile duct mucoepidermoid carcinoma 9.9 MUC5AC KRT7
16 mucoepidermoid carcinoma 9.9 MUC5AC KRT7
17 pancreatic mucinous cystadenoma 9.9 MUC5AC KRT7
18 biliary tract benign neoplasm 9.9 MUC5AC KRT7
19 methylmalonic acidemia 9.9 TCN2 CD320
20 endobronchial lipoma 9.9 MUC5AC KRT7
21 solid adenocarcinoma with mucin production 9.9 MUC5AC KRT7
22 teratoma 9.9 KRT7 CDX2
23 cervical adenocarcinoma 9.9 KRT7 CDX2
24 ovary neuroendocrine neoplasm 9.9 KRT7 CDX2
25 anal canal paget's disease 9.9 KRT7 CDX2
26 anal paget's disease 9.9 KRT7 CDX2
27 gastric signet ring cell adenocarcinoma 9.9 KRT7 CDX2
28 ureter adenocarcinoma 9.9 KRT7 CDX2
29 mucinous adenofibroma 9.8 KRT7 CDX2
30 pancreatic foamy gland adenocarcinoma 9.8 KRT7 CDX2
31 adenosquamous colon carcinoma 9.8 KRT7 CDX2
32 bartholin's gland disease 9.8 KRT7 CDX2
33 bartholin's gland carcinoma 9.8 KRT7 CDX2
34 vulva adenocarcinoma 9.8 KRT7 CDX2
35 vaginal tubulovillous adenoma 9.8 KRT7 CDX2
36 female urethral cancer 9.8 KRT7 CDX2
37 cystitis cystica 9.8 KRT7 CDX2
38 ovarian seromucinous carcinoma 9.8 KRT7 CDX2
39 rectum neuroendocrine neoplasm 9.8 KRT7 CDX2
40 mucinous ovarian cystadenoma 9.8 KRT7 CDX2
41 sigmoid neoplasm 9.8 KRT7 CDX2
42 krukenberg carcinoma 9.8 KRT7 CDX2
43 megaloblastic anemia 9.8 TCN2 CD320
44 jejunal cancer 9.8 KRT7 CDX2
45 appendiceal neoplasm 9.8 KRT7 CDX2
46 appendix adenocarcinoma 9.8 KRT7 CDX2
47 mucinous bronchioloalveolar adenocarcinoma 9.8 KRT7 CDX2
48 jejunal adenocarcinoma 9.8 KRT7 CDX2
49 gastric diffuse adenocarcinoma 9.8 KRT7 CDX2
50 linitis plastica 9.8 KRT7 CDX2

Graphical network of the top 20 diseases related to Anus Adenocarcinoma:



Diseases related to Anus Adenocarcinoma

Symptoms & Phenotypes for Anus Adenocarcinoma

Drugs & Therapeutics for Anus Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Anus Adenocarcinoma

Genetic Tests for Anus Adenocarcinoma

Anatomical Context for Anus Adenocarcinoma

MalaCards organs/tissues related to Anus Adenocarcinoma:

40
Cortex, Adrenal Gland, Appendix, Colon, Breast, Ovary, Spleen

Publications for Anus Adenocarcinoma

Articles related to Anus Adenocarcinoma:

(show all 20)
# Title Authors PMID Year
1
Patterns of Care and Comparison of Outcomes Between Primary Anal Squamous Cell Carcinoma and Anal Adenocarcinoma. 61
31725581 2019
2
Impact of Surgical Resection on Survival Outcomes After Chemoradiotherapy in Anal Adenocarcinoma. 61
31590155 2019
3
Anal adenocarcinoma: Treatment outcomes and trends in a rare disease entity. 61
31173487 2019
4
Lifestyle and reproductive risk factors associated with anal cancer in women aged over 50 years. 61
25867258 2015
5
Primary anal mucinous adenocarcinoma: a case series. 61
21429457 2011
6
[Anal mucinous adenocarcinoma arising in long standing fistula-in-ano]. 61
18357666 2008
7
Phase I study of capecitabine and oxaliplatin in combination with the proteasome inhibitor bortezomib in patients with advanced solid tumors. 61
18376220 2008
8
Is histopathological evidence really essential for making a surgical decision about mucinous carcinoma arising in a perianal fistula? Report of a case. 61
18516539 2008
9
[Anal cancer in Iceland 1987-2003. A population based study]. 61
16741319 2006
10
Primary adenocarcinoma of the anus treated with combined modality therapy. 61
14530668 2003
11
Management of primary anal canal adenocarcinoma: a large retrospective study from the Rare Cancer Network. 61
12873671 2003
12
Chemoradiation for adenocarcinoma of the anus. 61
12573754 2003
13
Perianal mucinous adenocarcinoma: unusual case presentations and review of the literature. 61
12641361 2003
14
Primary adenocarcinoma of the anus: a retrospective analysis. 61
10613313 1999
15
[Mucinous adenocarcinoma of the anal region. Study of 4 cases]. 61
7577129 1995
16
Immunohistochemical stains in extramammary Paget's disease. 61
1384380 1992
17
The aetiology and surgery of carcinoma of the anus, rectum and sigmoid colon in Crohn's disease. Negative correlation with human papillomavirus type 16 (HPV 16). 61
1657651 1991
18
Human papillomavirus detection in adenocarcinoma of the anus. 61
1850518 1991
19
[Adenocarcinoma of the anus. Therapeutic considerations]. 61
1015696 1976
20
Radiotherapy in adenocarcinoma of the anus. 61
20343609 1947

Variations for Anus Adenocarcinoma

Expression for Anus Adenocarcinoma

Search GEO for disease gene expression data for Anus Adenocarcinoma.

Pathways for Anus Adenocarcinoma

GO Terms for Anus Adenocarcinoma

Biological processes related to Anus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin metabolic process GO:0009235 8.96 TCN2 CD320
2 cobalamin transport GO:0015889 8.62 TCN2 CD320

Molecular functions related to Anus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 8.62 TCN2 CD320

Sources for Anus Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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