MCID: ANS001
MIFTS: 19

Anus Basaloid Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Anus Basaloid Carcinoma

MalaCards integrated aliases for Anus Basaloid Carcinoma:

Name: Anus Basaloid Carcinoma 12 15
Basaloid Carcinoma of the Anus 12 73
Anal Basaloid Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7174
NCIt 50 C8256
UMLS 73 C0280470

Summaries for Anus Basaloid Carcinoma

MalaCards based summary : Anus Basaloid Carcinoma, also known as basaloid carcinoma of the anus, is related to apocrine sweat gland neoplasm and cystic basal cell carcinoma. An important gene associated with Anus Basaloid Carcinoma is CYLD (CYLD Lysine 63 Deubiquitinase). The drugs Cisplatin and Fluorouracil have been mentioned in the context of this disorder.

Related Diseases for Anus Basaloid Carcinoma

Graphical network of the top 20 diseases related to Anus Basaloid Carcinoma:



Diseases related to Anus Basaloid Carcinoma

Symptoms & Phenotypes for Anus Basaloid Carcinoma

Drugs & Therapeutics for Anus Basaloid Carcinoma

Drugs for Anus Basaloid Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 3,Phase 2 15663-27-1 84093 441203 2767
2
Fluorouracil Approved Phase 3,Phase 2 51-21-8 3385
3 Immunosuppressive Agents Phase 3,Phase 2
4 Antimetabolites Phase 3,Phase 2
5 Antimetabolites, Antineoplastic Phase 3,Phase 2
6 Alkylating Agents Phase 3,Phase 2
7 Mitomycins Phase 3,Phase 2
8 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
9 Anti-Bacterial Agents Phase 3,Phase 2
10 Antibiotics, Antitubercular Phase 3,Phase 2
11
Cetuximab Approved Phase 2 205923-56-4 56842117 2333
12
nivolumab Approved Phase 2 946414-94-4
13
Capecitabine Approved, Investigational Phase 2 154361-50-9 60953
14
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
15
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
16 Antibodies Phase 2
17 Immunoglobulins Phase 2
18 Antibodies, Monoclonal Phase 2
19 Albumin-Bound Paclitaxel Phase 2
20 Antimitotic Agents Phase 2
21 Antineoplastic Agents, Phytogenic Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer Unknown status NCT00003652 Phase 3 cisplatin;fluorouracil
2 Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer Completed NCT00003596 Phase 3 cisplatin;fluorouracil;mitomycin C
3 Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer Completed NCT00025090 Phase 3 cisplatin;fluorouracil;mitomycin C
4 Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer Completed NCT00423293 Phase 2 fluorouracil;mitomycin C
5 Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer Completed NCT00324415 Phase 2 cisplatin;fluorouracil
6 Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer Recruiting NCT03233711 Phase 2
7 Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer Active, not recruiting NCT02560298 Phase 2 Capecitabine;Carboplatin;Cisplatin;Fluorouracil;Paclitaxel
8 Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer Active, not recruiting NCT00316888 Phase 2 cisplatin;fluorouracil

Search NIH Clinical Center for Anus Basaloid Carcinoma

Genetic Tests for Anus Basaloid Carcinoma

Anatomical Context for Anus Basaloid Carcinoma

Publications for Anus Basaloid Carcinoma

Variations for Anus Basaloid Carcinoma

Expression for Anus Basaloid Carcinoma

Search GEO for disease gene expression data for Anus Basaloid Carcinoma.

Pathways for Anus Basaloid Carcinoma

GO Terms for Anus Basaloid Carcinoma

Biological processes related to Anus Basaloid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 8.96 PTGER4 TAC1
2 positive regulation of cytosolic calcium ion concentration GO:0007204 8.62 PTGER4 TAC1

Sources for Anus Basaloid Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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