Aortic Aneurysm, Familial Abdominal, 2 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Aortic Aneurysm, Familial Abdominal, 2

MalaCards integrated aliases for Aortic Aneurysm, Familial Abdominal, 2:

Name: Aortic Aneurysm, Familial Abdominal, 2 ⁵⁷

Aortic Aneurysm, Familial Abdominal 2 ⁵⁷ ¹³ ⁷¹

Aaa2 ⁵⁷

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases
Anatomical: Cardiovascular diseases Blood diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM® ⁵⁷ 609782

OMIM Phenotypic Series ⁵⁷ PS100070

MedGen ⁴¹ C1853364

UMLS ⁷¹ C1853364

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Summaries for Aortic Aneurysm, Familial Abdominal, 2

MalaCards based summary : Aortic Aneurysm, Familial Abdominal, 2, is also known as aortic aneurysm, familial abdominal 2. An important gene associated with Aortic Aneurysm, Familial Abdominal, 2 is AAA2 (Aortic Aneurysm, Familial Abdominal 2). Affiliated tissues include liver.

More information from OMIM: 609782 PS100070

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Related Diseases for Aortic Aneurysm, Familial Abdominal, 2

Diseases in the Familial Abdominal Aortic Aneurysm family:

Aortic Aneurysm, Familial Abdominal, 1	Aortic Aneurysm, Familial Abdominal, 2
Aortic Aneurysm, Familial Abdominal, 3	Aortic Aneurysm, Familial Abdominal, 4

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Symptoms & Phenotypes for Aortic Aneurysm, Familial Abdominal, 2

Clinical features from OMIM®:

609782 (Updated 05-Mar-2021)

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Drugs & Therapeutics for Aortic Aneurysm, Familial Abdominal, 2

Search Clinical Trials , NIH Clinical Center for Aortic Aneurysm, Familial Abdominal, 2

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Genetic Tests for Aortic Aneurysm, Familial Abdominal, 2

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Anatomical Context for Aortic Aneurysm, Familial Abdominal, 2

MalaCards organs/tissues related to Aortic Aneurysm, Familial Abdominal, 2:

⁴⁰

Liver

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Publications for Aortic Aneurysm, Familial Abdominal, 2

Articles related to Aortic Aneurysm, Familial Abdominal, 2:

(show all 14)

#	Title	Authors	PMID	Year
1	Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13. ⁵⁷	Shibamura H...Kuivaniemi H	15096456	2004
2	Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. ⁶¹	Deville C...Saibil HR	31216466	2019
3	Dynamics of Allosteric Transitions in Dynein. ⁶¹	Goldtzvik Y...Thirumalai D	30270176	2018
4	Electrostatic interactions between middle domain motif-1 and the AAA1 module of the bacterial ClpB chaperone are essential for protein disaggregation. ⁶¹	Sugita S...Watanabe YH	30327424	2018
5	The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. ⁶¹	Sosnowski P...Schmidt H	30460895	2018
6	Coarse-grained modeling of the structural states and transition underlying the powerstroke of dynein motor domain. ⁶¹	Zheng W	22519354	2012
7	Insights into dynein motor domain function from a 3.3-Å crystal structure. ⁶¹	Schmidt H...Carter AP	22426545	2012
8	AAA+ Ring and linker swing mechanism in the dynein motor. ⁶¹	Roberts AJ...Burgess SA	19203583	2009
9	Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. ⁶¹	Horvat S...Milostic-Srb A	16722632	2006
10	Biochemical coupling of the two nucleotide binding domains of ClpB: covalent linkage is not a prerequisite for chaperone activity. ⁶¹	Beinker P...Reinstein J	16162497	2005
11	Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. ⁶¹	Reck-Peterson SL...Vale RD	14755060	2004
12	Potent side-chain to side-chain cyclized dermorphin analogues containing a carbonyl bridge. ⁶¹	Filip K...Izdebski J	14620130	2003
13	Antibiotic selective pressure for the maintenance of antibiotic resistant genes in coliform bacteria isolated from the aquatic environment. ⁶¹	Park JC...Lee WB	12639037	2003
14	Immunochemical characterization of anti-albumin antibodies in liver diseases. ⁶¹	Onica D...Belascu I	6872343	1983

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Genes for Aortic Aneurysm, Familial Abdominal, 2

Genes related to Aortic Aneurysm, Familial Abdominal, 2 (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	AAA2	Aortic Aneurysm, Familial Abdominal 2	Genetic Locus	58.94	Genetic linkage ⁵⁷ GeneCards inferred via : Gene name (show sections)

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Variations for Aortic Aneurysm, Familial Abdominal, 2

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Expression for Aortic Aneurysm, Familial Abdominal, 2

Search GEO for disease gene expression data for Aortic Aneurysm, Familial Abdominal, 2.

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Pathways for Aortic Aneurysm, Familial Abdominal, 2

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GO Terms for Aortic Aneurysm, Familial Abdominal, 2

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Sources for Aortic Aneurysm, Familial Abdominal, 2

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

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¹⁵ DISEASES

¹⁶ DrugBank

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¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Aortic Aneurysm, Familial Abdominal, 2 (AAA2)

Aliases & Classifications for Aortic Aneurysm, Familial Abdominal, 2

MalaCards integrated aliases for Aortic Aneurysm, Familial Abdominal, 2:

Classifications:

External Ids:

Summaries for Aortic Aneurysm, Familial Abdominal, 2

Related Diseases for Aortic Aneurysm, Familial Abdominal, 2

Diseases in the Familial Abdominal Aortic Aneurysm family:

Symptoms & Phenotypes for Aortic Aneurysm, Familial Abdominal, 2

Clinical features from OMIM®:

Drugs & Therapeutics for Aortic Aneurysm, Familial Abdominal, 2

Genetic Tests for Aortic Aneurysm, Familial Abdominal, 2

Anatomical Context for Aortic Aneurysm, Familial Abdominal, 2

MalaCards organs/tissues related to Aortic Aneurysm, Familial Abdominal, 2:

Publications for Aortic Aneurysm, Familial Abdominal, 2

Articles related to Aortic Aneurysm, Familial Abdominal, 2:

Genes for Aortic Aneurysm, Familial Abdominal, 2

Genes related to Aortic Aneurysm, Familial Abdominal, 2 (1 elite genes):

Variations for Aortic Aneurysm, Familial Abdominal, 2

Expression for Aortic Aneurysm, Familial Abdominal, 2

Pathways for Aortic Aneurysm, Familial Abdominal, 2

GO Terms for Aortic Aneurysm, Familial Abdominal, 2

Sources for Aortic Aneurysm, Familial Abdominal, 2