AAA2
MCID: ART151
MIFTS: 14

Aortic Aneurysm, Familial Abdominal, 2 (AAA2)

Categories: Blood diseases, Cardiovascular diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Aortic Aneurysm, Familial Abdominal, 2

MalaCards integrated aliases for Aortic Aneurysm, Familial Abdominal, 2:

Name: Aortic Aneurysm, Familial Abdominal, 2 56
Aortic Aneurysm, Familial Abdominal 2 56 13 71
Aaa2 56

Classifications:



External Ids:

OMIM 56 609782
OMIM Phenotypic Series 56 PS100070
MedGen 41 C1853364
UMLS 71 C1853364

Summaries for Aortic Aneurysm, Familial Abdominal, 2

MalaCards based summary : Aortic Aneurysm, Familial Abdominal, 2, also known as aortic aneurysm, familial abdominal 2, is related to familial abdominal aortic aneurysm. An important gene associated with Aortic Aneurysm, Familial Abdominal, 2 is AAA2 (Aortic Aneurysm, Familial Abdominal 2). Affiliated tissues include liver.

More information from OMIM: 609782 PS100070

Related Diseases for Aortic Aneurysm, Familial Abdominal, 2

Diseases in the Familial Abdominal Aortic Aneurysm family:

Aortic Aneurysm, Familial Abdominal, 1 Aortic Aneurysm, Familial Abdominal, 2
Aortic Aneurysm, Familial Abdominal, 3 Aortic Aneurysm, Familial Abdominal, 4

Diseases related to Aortic Aneurysm, Familial Abdominal, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 familial abdominal aortic aneurysm 11.3

Symptoms & Phenotypes for Aortic Aneurysm, Familial Abdominal, 2

Clinical features from OMIM:

609782

Drugs & Therapeutics for Aortic Aneurysm, Familial Abdominal, 2

Search Clinical Trials , NIH Clinical Center for Aortic Aneurysm, Familial Abdominal, 2

Genetic Tests for Aortic Aneurysm, Familial Abdominal, 2

Anatomical Context for Aortic Aneurysm, Familial Abdominal, 2

MalaCards organs/tissues related to Aortic Aneurysm, Familial Abdominal, 2:

40
Liver

Publications for Aortic Aneurysm, Familial Abdominal, 2

Articles related to Aortic Aneurysm, Familial Abdominal, 2:

(show all 14)
# Title Authors PMID Year
1
Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13. 56
15096456 2004
2
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. 61
31216466 2019
3
Dynamics of Allosteric Transitions in Dynein. 61
30270176 2018
4
Electrostatic interactions between middle domain motif-1 and the AAA1 module of the bacterial ClpB chaperone are essential for protein disaggregation. 61
30327424 2018
5
The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1. 61
30460895 2018
6
Coarse-grained modeling of the structural states and transition underlying the powerstroke of dynein motor domain. 61
22519354 2012
7
Insights into dynein motor domain function from a 3.3-Å crystal structure. 61
22426545 2012
8
AAA+ Ring and linker swing mechanism in the dynein motor. 61
19203583 2009
9
Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. 61
16722632 2006
10
Biochemical coupling of the two nucleotide binding domains of ClpB: covalent linkage is not a prerequisite for chaperone activity. 61
16162497 2005
11
Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. 61
14755060 2004
12
Potent side-chain to side-chain cyclized dermorphin analogues containing a carbonyl bridge. 61
14620130 2003
13
Antibiotic selective pressure for the maintenance of antibiotic resistant genes in coliform bacteria isolated from the aquatic environment. 61
12639037 2003
14
Immunochemical characterization of anti-albumin antibodies in liver diseases. 61
6872343 1983

Variations for Aortic Aneurysm, Familial Abdominal, 2

Expression for Aortic Aneurysm, Familial Abdominal, 2

Search GEO for disease gene expression data for Aortic Aneurysm, Familial Abdominal, 2.

Pathways for Aortic Aneurysm, Familial Abdominal, 2

GO Terms for Aortic Aneurysm, Familial Abdominal, 2

Sources for Aortic Aneurysm, Familial Abdominal, 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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