MCID: ART015
MIFTS: 16

Aortic Valve Prolapse

Categories: Cardiovascular diseases

Aliases & Classifications for Aortic Valve Prolapse

MalaCards integrated aliases for Aortic Valve Prolapse:

Name: Aortic Valve Prolapse 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5232
MeSH 45 D001023
UMLS 74 C0003505

Summaries for Aortic Valve Prolapse

MalaCards based summary : Aortic Valve Prolapse is related to ventricular septal defect and aortic valve insufficiency. An important gene associated with Aortic Valve Prolapse is KIDINS220 (Kinase D Interacting Substrate 220). Affiliated tissues include heart, and related phenotypes are Decreased homologous recombination repair frequency and Decreased homologous recombination repair frequency

Related Diseases for Aortic Valve Prolapse

Diseases related to Aortic Valve Prolapse via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ventricular septal defect 10.6
2 aortic valve insufficiency 10.5
3 aortic valve disease 1 10.0
4 orthostatic intolerance 10.0
5 rheumatic heart disease 10.0
6 heart disease 10.0
7 patent foramen ovale 10.0
8 aortitis 10.0
9 laubry-pezzi syndrome 10.0

Graphical network of the top 20 diseases related to Aortic Valve Prolapse:



Diseases related to Aortic Valve Prolapse

Symptoms & Phenotypes for Aortic Valve Prolapse

GenomeRNAi Phenotypes related to Aortic Valve Prolapse according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased homologous recombination repair frequency GR00236-A-1 8.8 ACOT13 KIDINS220
2 Decreased homologous recombination repair frequency GR00236-A-2 8.8 ACOT13

Drugs & Therapeutics for Aortic Valve Prolapse

Search Clinical Trials , NIH Clinical Center for Aortic Valve Prolapse

Cochrane evidence based reviews: aortic valve prolapse

Genetic Tests for Aortic Valve Prolapse

Anatomical Context for Aortic Valve Prolapse

MalaCards organs/tissues related to Aortic Valve Prolapse:

42
Heart

Publications for Aortic Valve Prolapse

Articles related to Aortic Valve Prolapse:

(show all 50)
# Title Authors Year
1
Transcatheter closure of ventricular septal defect in aortic valve prolapse and aortic regurgitation. ( 30170648 )
2018
2
Measurement of Aortic Valve Coaptation and Effective Height Using Echocardiography in Patients with Ventricular Septal Defects and Aortic Valve Prolapse. ( 28108755 )
2017
3
Aortic valve prolapse misdiagnosed as aortic sinus aneurysm in patients with ventricular septal defect. Analysis of the echocardiographic findings. ( 28397952 )
2017
4
Evaluation of Ventricular Septal Defect with Special Reference to the Spontaneous Closure Rate, Subaortic Ridge, and Aortic Valve Prolapse II. ( 28401252 )
2017
5
Aortic Valve Prolapse and Aortic Regurgitation During Long-Term Follow Up in Children with Ventricular Septal Defect. ( 30207110 )
2017
6
Case images: a rare cause of severe aortic valve regurgitation: isolated aortic valve prolapse. ( 25782130 )
2015
7
Transcatheter closure of ventricular septal defect in patients with aortic valve prolapse and mild aortic regurgitation: feasibility and preliminary outcome. ( 25975505 )
2015
8
Demonstration of doubly committed juxta-arterial ventricular septal defect with aortic valve prolapse by cardiac computed tomography. ( 24582047 )
2014
9
'Aortic valve prolapse' in rheumatic heart disease. ( 27279057 )
2014
10
Reliability and identification of aortic valve prolapse in the horse. ( 23311963 )
2013
11
Anatomic and functional aortic valvuloplasty for correction of aortic valve prolapse in ventricular septal defect with aortic insufficiency. ( 21172547 )
2011
12
An object in the proximal left ventricular outflow tract during late diastole: aortic valve prolapse, mass, or normal anatomy? ( 19231244 )
2010
13
Leaflet suspension and subvalvular annuloplasty in aortic valve prolapse. ( 19643852 )
2009
14
An atypical cause of aortic valve prolapse. ( 19699939 )
2009
15
Aortic valve prolapse and insufficiency due to elongation of a fibrous strand. ( 20099703 )
2009
16
Aortic insufficiency due to a partial left-coronary aortic valve prolapse and the detection of two small interatrial jets after blunt thoracic trauma. ( 17064799 )
2007
17
Left valsalva sinus aneurysm rupture into left atrium and aortic valve prolapse confirmed with transesophageal echocardiography. ( 17555925 )
2007
18
Repair of trileaflet aortic valve prolapse: mid-term outcome in patients with normal aortic root morphology. ( 17669769 )
2007
19
Aortic valve prolapse associated with outlet-type ventricular septal defect. ( 15797078 )
2005
20
Repair of aortic valve prolapse: experience with 44 patients. ( 15302061 )
2004
21
Aortic valve prolapse and aortic regurgitation in patients with ventricular septal defect. ( 12360382 )
2003
22
Evolution of ventricular septal defect with special reference to spontaneous closure rate, subaortic ridge and aortic valve prolapse. ( 12360383 )
2003
23
Diastolic musical murmur changing with cardiac cycle. Aortic valve prolapse due to myxomatous degeneration. ( 12728541 )
2003
24
Aortic valve prolapse in subpulmonic ventricular septal defect. ( 14700147 )
2003
25
Influence of surgery on aortic valve prolapse and aortic regurgitation in doubly committed subarterial ventricular septal defect. ( 10606121 )
1999
26
Is early surgery always necessary in patients with aortic valve prolapse complicating an Eisenmenger-type ventricular septal defect? ( 9695295 )
1998
27
Aortic valve prolapse and aortic regurgitation associated with subpulmonic ventricular septal defect. ( 9164909 )
1997
28
Aneurysms of all sinuses of Valsalva and aortic valve prolapse secondary to Behçet's disease. ( 8922939 )
1996
29
Surgical management of ventricular septal defect with aortic valve prolapse: clinical considerations and results. ( 7546804 )
1995
30
Echocardiographic evaluation of the development of aortic valve prolapse in supracristal ventricular septal defect. ( 7758512 )
1995
31
Isolated aortic valve prolapse due to cuspal inequality causing aortic regurgitation. ( 7744463 )
1994
32
Aortic valve prolapse with aortic regurgitation assessed by Doppler color-flow echocardiography. ( 1442499 )
1992
33
Acute aortic valve prolapse in Marfan's syndrome. ( 2041858 )
1991
34
Ventricular septal defect closure without aortic valve plication in patients with aortic valve prolapse. ( 2337043 )
1990
35
[Prevalence of tricuspid and aortic valve prolapse in patients with mitral valve prolapse]. ( 2629684 )
1989
36
Results of surgery for aortic regurgitation due to aortic valve prolapse. ( 3239439 )
1988
37
Postinflammatory mitral and aortic valve prolapse: a clinical and pathological study. ( 3594777 )
1987
38
Echocardiographic follow-up in Marfan's syndrome: mitral, tricuspid, and aortic valve prolapse with calcification of patent foramen ovale. ( 3098792 )
1986
39
Evaluation of aortic valve prolapse in ventricular septal defect. ( 3756041 )
1986
40
Ventricular septal defect in Chinese with aortic valve prolapse and aortic regurgitation. ( 3759798 )
1986
41
Pathological anatomy of ventricular septal defect associated with aortic valve prolapse and regurgitation. ( 3759799 )
1986
42
Cross-sectional echocardiography in the evaluation of aortic valve prolapse associated with ventricular septal defect. ( 3766381 )
1986
43
Aortic regurgitation due to aortic valve prolapse. ( 3993589 )
1985
44
Prevalence and clinical significance of aortic valve prolapse. ( 4015927 )
1985
45
Aortic valve prolapse in congenital and acquired systemic disease. ( 4026490 )
1985
46
Prevalence of aortic valve prolapse with bicuspid aortic valve and its relation to aortic regurgitation: a cross-sectional echocardiographic study. ( 6507297 )
1984
47
Aortic valve prolapse due to syphilitic aortitis. ( 6731276 )
1984
48
Rheumatoid aortic valve prolapse requiring emergency aortic valve replacement. ( 7362719 )
1980
49
Cross-sectional echocardiographic detection of aortic valve prolapse. ( 7405799 )
1980
50
Aortic valve prolapse associated with ventricular septal defect: echocardiographic features. ( 466593 )
1979

Variations for Aortic Valve Prolapse

Expression for Aortic Valve Prolapse

Search GEO for disease gene expression data for Aortic Valve Prolapse.

Pathways for Aortic Valve Prolapse

GO Terms for Aortic Valve Prolapse

Sources for Aortic Valve Prolapse

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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