MCID: ART012
MIFTS: 32

Aortitis

Categories: Cardiovascular diseases

Aliases & Classifications for Aortitis

Summaries for Aortitis

MalaCards based summary : Aortitis is related to temporal arteritis and spondyloarthropathy 1. An important gene associated with Aortitis is CRP (C-Reactive Protein). The drugs rituximab and Immunoglobulin G have been mentioned in the context of this disorder. Affiliated tissues include colon, heart and thyroid.

Wikipedia : 76 Aortitis is the inflammation of the aortic wall. The disorder is potentially life-threatening and rare.... more...

Related Diseases for Aortitis

Diseases related to Aortitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)
# Related Disease Score Top Affiliating Genes
1 temporal arteritis 30.1 CRP SMUG1
2 spondyloarthropathy 1 30.0 CRP MRAP
3 vasculitis 29.9 CRP MPO
4 appendicitis 29.6 CRP MPO
5 ulcerative colitis 29.3 CRP MPO
6 pneumonia 29.2 CRP MPO
7 mediastinitis 28.8 CRP MPO RERE
8 igg4-related aortitis 12.0
9 takayasu arteritis 11.4
10 ovarian squamous cell carcinoma 10.5 CRP SMUG1
11 cartilage disease 10.5 CRP SMUG1
12 central nervous system vasculitis 10.5 CRP SMUG1
13 tuberculous peritonitis 10.5 CRP SMUG1
14 lemierre's syndrome 10.5 CRP SMUG1
15 pyuria 10.5 CRP MRAP
16 lipid pneumonia 10.5 CRP SMUG1
17 tenosynovitis 10.5 CRP MRAP
18 spinal disease 10.5 CRP MRAP
19 xanthogranulomatous pyelonephritis 10.5 CRP SMUG1
20 aneurysm 10.5
21 bursitis 10.5 CRP MRAP
22 intermittent explosive disorder 10.5 CRP SMUG1
23 tendinitis 10.5 CRP MRAP
24 endocardium disease 10.5 CRP SMUG1
25 mesenteric lymphadenitis 10.4 CRP MRAP
26 mononeuritis multiplex 10.4 CRP MPO
27 rapidly progressive glomerulonephritis 10.4 CRP MPO
28 hypersensitivity vasculitis 10.4 CRP MPO
29 tracheal cancer 10.4 NT5C1B SMUG1
30 hypersensitivity reaction type iii disease 10.4 CRP MPO
31 palindromic rheumatism 10.3 CRP MRAP
32 pulmonary alveolar microlithiasis 10.3 NT5C1B SMUG1
33 polyarteritis nodosa 10.3 CRP MPO
34 arteritic anterior ischemic optic neuropathy 10.3 CRP MPO
35 ochronosis 10.3 MRAP NT5C1B
36 pleural disease 10.3 CRP MPO
37 hypersensitivity reaction type iv disease 10.3 MRAP SMUG1
38 proctitis 10.3 CRP MPO
39 pericardium cancer 10.3 MPO SMUG1
40 multiple cranial nerve palsy 10.3 CRP MPO
41 vulvitis 10.3 MPO MRAP
42 aortic aneurysm 10.2
43 pelvic inflammatory disease 10.2 CRP MPO
44 actinomycosis 10.2 RERE SMUG1
45 pericardial mesothelioma 10.2 MPO SMUG1
46 suppurative cholangitis 10.2 CRP MPO
47 pleurisy 10.2 CRP MPO
48 bone inflammation disease 10.2 CRP MRAP
49 autoinflammation, lipodystrophy, and dermatosis syndrome 10.2 CRP MPO
50 peritonitis 10.1 CRP MPO

Graphical network of the top 20 diseases related to Aortitis:



Diseases related to Aortitis

Symptoms & Phenotypes for Aortitis

Drugs & Therapeutics for Aortitis

Drugs for Aortitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
2 Immunoglobulin G Phase 1, Phase 2
3 Antibodies Phase 1, Phase 2
4 Immunoglobulins Phase 1, Phase 2
5 Antirheumatic Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission. Recruiting NCT03244709 Phase 4 Tocilizumab
2 Rituximab in IgG4-RD: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2 Rituximab
3 Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis Completed NCT01795456
4 VCRC Longitudinal Protocol for Aortitis Recruiting NCT03022331
5 Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria Recruiting NCT03133949
6 VCRC Tissue Repository Recruiting NCT02967068

Search NIH Clinical Center for Aortitis

Cochrane evidence based reviews: aortitis

Genetic Tests for Aortitis

Anatomical Context for Aortitis

MalaCards organs/tissues related to Aortitis:

41
Colon, Heart, Thyroid, Liver, Bone, Neutrophil, Skin

Publications for Aortitis

Articles related to Aortitis:

(show top 50) (show all 647)
# Title Authors Year
1
Noninfectious aortitis: Experience with tocilizumab in a regional hospital. ( 29398465 )
2018
2
Additional Diagnostic Value of Combined Angio-Computed Tomography and<sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography in Infectious Aortitis. ( 29055634 )
2018
3
A Clinicopathological Analysis of Six Autopsy Cases of Sudden Unexpected Death Due to Infectious Aortitis in Patients with Aortic Tears. ( 29321404 )
2018
4
Infectious Aortitis: A Life-Threatening Endovascular Complication of Nontyphoidal <i>Salmonella</i> Bacteremia. ( 29808097 )
2018
5
Aortitis as a Rare Cause of Aortic Aneurysm and Valve Regurgitation: Is Repair Precluded? ( 29662705 )
2018
6
Subclinical aortitis after starting nivolumab in a patient with metastatic melanoma. A case of drug-associated aortitis? ( 29799390 )
2018
7
Impact of Medical Therapy on Late Morbidity and Mortality After Aortic Aneurysm Repair for Aortitis. ( 29408240 )
2018
8
Recurrent ventricular arrhythmia in a patient with aortitis and myocardial inflammation due to possible immunoglobulin G4-related disease. ( 29722185 )
2018
9
Conservative treatment of non-aneurysmal infectious aortitis: a case report and review of the literature. ( 29745308 )
2018
10
Infectious aortitis: A bridge too far. ( 29249489 )
2018
11
Imaging giant cell arteritis and Aortitis in contrast enhanced 18F-FDG PET/CT: Which imaging score correlates best with laboratory inflammation markers? ( 29362158 )
2018
12
Response to Jolobe: 'Beyond identification of GCA-related thoracic aortitis'. ( 29860324 )
2018
13
Surgical strategy for refractory aortitis. ( 29404904 )
2018
14
Myelodysplastic syndrome presenting as a BehAset's-like disease with aortitis. ( 29545422 )
2018
15
Two-stage surgical approach for ruptured Salmonella aortitis. ( 29089095 )
2018
16
A case of giant cell arteritis associated with a culture proven Coxiella burnetii aortitis. ( 29408476 )
2018
17
Beyond identification of GCA-related thoracic aortitis. ( 29860448 )
2018
18
Aortitis With an Aneurysm at Initial Presentation of Crohn Disease. ( 29927874 )
2018
19
Tuberculous Aortitis Associated With Pleuritis and Spondylitis. ( 29398471 )
2018
20
Acute infectious aortitis presenting as pyelonephritis. ( 29903668 )
2018
21
A rare case of <i>Clostridium septicum</i> aortitis with colon adenocarcinoma. ( 29707691 )
2018
22
Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by<sup>18</sup>F-fluorodeoxyglucose Positron Emission Tomography. ( 29321427 )
2018
23
Efficacy of tocilizumab highlighted by FDG-PET/CT in a patient with relapsing polychondritis-associated aortitis. ( 28965131 )
2017
24
Contrast-enhanced magnetic resonance imaging to detect chronic aortic dissection complicated by acute aortitis. ( 28828099 )
2017
25
Successful Hybrid Neurovascular Surgery for a Ruptured Basilar Artery Dissecting Aneurysm in a Patient with Jeopardized Collateral Circulation Associated with Aortitis Syndrome. ( 28602923 )
2017
26
Thoracic Aortitis Due to Salmonella enteritidis. ( 28754550 )
2017
27
A case series of surgically diagnosed idiopathic aortitis in a Canadian centre: a retrospective study. ( 28641275 )
2017
28
Cogan's syndrome - A rare aortitis, difficult to diagnose but with therapeutic potential. ( 29489984 )
2017
29
Giant cell aortitis leading to Stanford type B and type A aortic dissection. ( 29051823 )
2017
30
eComment. The quest for elusive causative microbiological agents of infectious ascending aortitis. ( 28881944 )
2017
31
Clostridium septicum aortitis with synchronous ascending colon and rectal adenocarcinoma. ( 28655990 )
2017
32
Transient aortitis documented by positron emission tomography in a case series of men and transgender women infected with syphilis. ( 28866636 )
2017
33
Repeated isolated bilateral coronary ostial stenosis related to the syphilitic aortitis. ( 28651312 )
2017
34
Syphilitic aortitis: The bigger picture. ( 28528717 )
2017
35
Double-locus lymphoplasmacytic aortitis. ( 28893088 )
2017
36
Takayasus's Aortitis Induced Ascending Aorta Dissection. ( 29701396 )
2017
37
Thoracic aortitis and aortic dissection following pegfilgrastim administration. ( 28549110 )
2017
38
Diagnosis, Management, and Outcome of Aortitis at a Single Center. ( 28859604 )
2017
39
Sustained response to tocilizumab in a patient with relapsing polychondritis complicated by aortitis. ( 28229816 )
2017
40
Hepatitis C Virus-Associated Aortitis Caused by Type I Cryoglobulins. ( 29090238 )
2017
41
IgG4-Related Aortitis: Multimodality Imaging Approach. ( 28219573 )
2017
42
Noninfectious aortitis: what the cardiologist needs to know. ( 28806184 )
2017
43
Exceptional cause of chest pain: idiopathic ascending aortitis. ( 28990949 )
2017
44
IgG4-Aortopathy: An Underappreciated Cause of Non-Infectious Thoracic Aortitis. ( 28511923 )
2017
45
Aortitis: A new feature of Schnitzler syndrome. ( 28971133 )
2017
46
Non-infectious aortitis in an immunosuppressed renal transplant recipient with IgA nephropathy. ( 29054943 )
2017
47
A Rare Report of Infectious Emphysematous Aortitis Secondary to<i>Clostridium septicum</i>without Prior Vascular Intervention. ( 29075546 )
2017
48
Immunoglobulin G Subclass 4-Related Lymphoplasmacytic Thoracic Aortitis in a Patient with Acute Type A Aortic Dissection. ( 29279461 )
2017
49
Isolated Syphilitic Aortitis: A Rare Association. ( 28528065 )
2017
50
A Rare Case of Paraneoplastic Aortitis Associated with Chronic Myelomonocytic Leukemia. ( 28630775 )
2017

Variations for Aortitis

Expression for Aortitis

Search GEO for disease gene expression data for Aortitis.

Pathways for Aortitis

GO Terms for Aortitis

Sources for Aortitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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