MCID: ART012
MIFTS: 33

Aortitis

Categories: Cardiovascular diseases

Aliases & Classifications for Aortitis

Summaries for Aortitis

MalaCards based summary : Aortitis is related to temporal arteritis and vasculitis. An important gene associated with Aortitis is CRP (C-Reactive Protein). The drugs rituximab and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include heart, colon and thyroid.

Wikipedia : 76 Aortitis is the inflammation of the aortic wall. The disorder is potentially life-threatening and rare.... more...

Related Diseases for Aortitis

Diseases related to Aortitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 temporal arteritis 30.5 CRP SMUG1
2 vasculitis 30.2 CRP MPO
3 spondyloarthropathy 1 30.2 CRP MRAP
4 coronary artery anomaly 29.5 CRP SMUG1
5 polyarteritis nodosa 29.5 CRP MPO
6 appendicitis 29.4 CRP MPO
7 pneumonia 29.2 CRP MPO
8 igg4-related aortitis 12.2
9 takayasu arteritis 11.6
10 aortic aneurysm 10.4
11 aortic valve insufficiency 10.4
12 endocarditis 10.3
13 spondylitis 10.2
14 arthritis 10.2
15 gastrointestinal tuberculosis 10.2 CRP SMUG1
16 cartilage disease 10.2 CRP SMUG1
17 central nervous system vasculitis 10.2 CRP SMUG1
18 tuberculous peritonitis 10.2 CRP SMUG1
19 pericardium disease 10.2 CRP SMUG1
20 discitis 10.2 CRP MRAP
21 xanthogranulomatous pyelonephritis 10.2 CRP SMUG1
22 pyuria 10.2 CRP MRAP
23 relapsing polychondritis 10.2
24 tenosynovitis 10.2 CRP MRAP
25 lemierre's syndrome 10.1 CRP SMUG1
26 bursitis 10.1 CRP MRAP
27 tendinitis 10.1 CRP MRAP
28 endocardium disease 10.1 CRP SMUG1
29 intermittent explosive disorder 10.1 CRP SMUG1
30 mesenteric lymphadenitis 10.1 CRP MRAP
31 renal tuberculosis 10.1 CRP MRAP
32 myocardial infarction 10.1
33 crohn's disease 10.1
34 pleural disease 10.1 CRP SMUG1
35 lymphatic system disease 10.1 CRP SMUG1
36 pulmonary alveolar microlithiasis 10.1 NT5C1B SMUG1
37 palindromic rheumatism 10.1 CRP MRAP
38 rheumatoid arthritis 10.1
39 aortic aneurysm, familial thoracic 1 10.1
40 renovascular hypertension 10.1
41 syphilis 10.1
42 ochronosis 10.1 MRAP NT5C1B
43 hypersensitivity reaction type iv disease 10.1 MRAP SMUG1
44 actinomycosis 10.1 RERE SMUG1
45 bone inflammation disease 10.1 CRP MRAP
46 adenocarcinoma 10.1
47 aortic coarctation 10.1
48 aortic valve disease 1 10.0 CRP MRAP
49 aortic aneurysm, familial abdominal, 1 10.0
50 systemic lupus erythematosus 10.0

Graphical network of the top 20 diseases related to Aortitis:



Diseases related to Aortitis

Symptoms & Phenotypes for Aortitis

Drugs & Therapeutics for Aortitis

Drugs for Aortitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
2 Antibodies Phase 1, Phase 2
3 Immunoglobulin G Phase 1, Phase 2
4 Immunoglobulins Phase 1, Phase 2
5 Antirheumatic Agents Phase 1, Phase 2
6 Immunologic Factors Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission. Recruiting NCT03244709 Phase 4 Tocilizumab
2 Rituximab in IgG4-RD: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2 Rituximab
3 Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis Completed NCT01795456
4 VCRC Longitudinal Protocol for Aortitis Recruiting NCT03022331
5 Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria Recruiting NCT03133949
6 VCRC Tissue Repository Recruiting NCT02967068

Search NIH Clinical Center for Aortitis

Cochrane evidence based reviews: aortitis

Genetic Tests for Aortitis

Anatomical Context for Aortitis

MalaCards organs/tissues related to Aortitis:

41
Heart, Colon, Thyroid, Liver, Kidney, Bone, Pituitary

Publications for Aortitis

Articles related to Aortitis:

(show top 50) (show all 925)
# Title Authors Year
1
Noninfectious aortitis: Experience with tocilizumab in a regional hospital. ( 29398465 )
2018
2
Additional Diagnostic Value of Combined Angio-Computed Tomography and<sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography in Infectious Aortitis. ( 29055634 )
2018
3
A Clinicopathological Analysis of Six Autopsy Cases of Sudden Unexpected Death Due to Infectious Aortitis in Patients with Aortic Tears. ( 29321404 )
2018
4
Infectious Aortitis: A Life-Threatening Endovascular Complication of Nontyphoidal <i>Salmonella</i> Bacteremia. ( 29808097 )
2018
5
Aortitis as a Rare Cause of Aortic Aneurysm and Valve Regurgitation: Is Repair Precluded? ( 29662705 )
2018
6
Subclinical aortitis after starting nivolumab in a patient with metastatic melanoma. A case of drug-associated aortitis? ( 29799390 )
2018
7
Impact of Medical Therapy on Late Morbidity and Mortality After Aortic Aneurysm Repair for Aortitis. ( 29408240 )
2018
8
Recurrent ventricular arrhythmia in a patient with aortitis and myocardial inflammation due to possible immunoglobulin G4-related disease. ( 29722185 )
2018
9
Conservative treatment of non-aneurysmal infectious aortitis: a case report and review of the literature. ( 29745308 )
2018
10
Infectious aortitis: A bridge too far. ( 29249489 )
2018
11
Imaging giant cell arteritis and Aortitis in contrast enhanced 18F-FDG PET/CT: Which imaging score correlates best with laboratory inflammation markers? ( 29362158 )
2018
12
Response to Jolobe: 'Beyond identification of GCA-related thoracic aortitis'. ( 29860324 )
2018
13
Surgical strategy for refractory aortitis. ( 29404904 )
2018
14
Myelodysplastic syndrome presenting as a BehAset's-like disease with aortitis. ( 29545422 )
2018
15
Two-stage surgical approach for ruptured Salmonella aortitis. ( 29089095 )
2018
16
A case of giant cell arteritis associated with a culture proven Coxiella burnetii aortitis. ( 29408476 )
2018
17
Beyond identification of GCA-related thoracic aortitis. ( 29860448 )
2018
18
Aortitis With an Aneurysm at Initial Presentation of Crohn Disease. ( 29927874 )
2018
19
Tuberculous Aortitis Associated With Pleuritis and Spondylitis. ( 29398471 )
2018
20
Acute infectious aortitis presenting as pyelonephritis. ( 29903668 )
2018
21
A rare case of <i>Clostridium septicum</i> aortitis with colon adenocarcinoma. ( 29707691 )
2018
22
Aspergillus aortitis in an immunocompetent patient presenting with acute endophthalmitis. ( 30344969 )
2018
23
A case of Brucella aortitis associated with development of thoracic aortic aneurysm and aortobronchial fistula. ( 30513449 )
2018
24
Eosinophilic aortitis with thoracic aortic aneurysm and rupture in a captive-born owl monkey. ( 30187922 )
2018
25
Management of Salmonella typhimurium sepsis with thoracic infectious aortitis using 18F-FDG PET/CT. ( 28188443 )
2018
26
Pyogenic Aortitis - Role of 18F-FDG Positron Emission Tomography/Computed Tomography in Aortic Infection Imaging. ( 28747614 )
2018
27
Cardiac Sarcoidosis Concomitant with Large-vessel Aortitis Detected by 18F-fluorodeoxyglucose Positron Emission Tomography. ( 29321427 )
2018
28
Gonococcal aortitis in a patient with fever of unknown origin. ( 29984511 )
2018
29
Pneumococcal urinary antigen test: A tool for pneumococcal aortitis diagnosis? ( 29998060 )
2018
30
Granulocyte colony-stimulating factors and aortitis: A rare adverse event. ( 30016548 )
2018
31
Aortitis. ( 30077362 )
2018
32
Clostridium septicum arthroplasty infection: beware of occult aortitis and malignancy. ( 30153761 )
2018
33
Aortitis Presenting as Fever of Unknown Origin. ( 30158332 )
2018
34
Idiopathic aortitis presenting as pyrexia of unknown origin and delirium. ( 30290748 )
2018
35
A Case of IgG4-Related Aortitis and Pericarditis: Diagnostic Challenges and Natural History. ( 30323165 )
2018
36
Drug-induced aortitis in a patient with ovarian cancer treated with bevacizumab combination therapy. ( 30342665 )
2018
37
A Case of IBD Immunosuppression Related Salmonella Aortitis Requiring Emergency Vascular Grafting. ( 30395221 )
2018
38
Incidence of Aortitis in Surgical Specimens of the Ascending Aorta Clinical Implications at Follow-Up. ( 30414447 )
2018
39
A case of syphilitic aortitis. ( 30517985 )
2018
40
Antineutrophil Cytoplasmic Antibody Vasculitis Causing Skull Base Inflammation and Aortitis. ( 30532374 )
2018
41
Efficacy of tocilizumab highlighted by FDG-PET/CT in a patient with relapsing polychondritis-associated aortitis. ( 28965131 )
2017
42
Contrast-enhanced magnetic resonance imaging to detect chronic aortic dissection complicated by acute aortitis. ( 28828099 )
2017
43
Successful Hybrid Neurovascular Surgery for a Ruptured Basilar Artery Dissecting Aneurysm in a Patient with Jeopardized Collateral Circulation Associated with Aortitis Syndrome. ( 28602923 )
2017
44
Thoracic Aortitis Due to Salmonella enteritidis. ( 28754550 )
2017
45
A case series of surgically diagnosed idiopathic aortitis in a Canadian centre: a retrospective study. ( 28641275 )
2017
46
Cogan's syndrome - A rare aortitis, difficult to diagnose but with therapeutic potential. ( 29489984 )
2017
47
Giant cell aortitis leading to Stanford type B and type A aortic dissection. ( 29051823 )
2017
48
eComment. The quest for elusive causative microbiological agents of infectious ascending aortitis. ( 28881944 )
2017
49
Clostridium septicum aortitis with synchronous ascending colon and rectal adenocarcinoma. ( 28655990 )
2017
50
Transient aortitis documented by positron emission tomography in a case series of men and transgender women infected with syphilis. ( 28866636 )
2017

Variations for Aortitis

Expression for Aortitis

Search GEO for disease gene expression data for Aortitis.

Pathways for Aortitis

GO Terms for Aortitis

Sources for Aortitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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