MCID: APC003
MIFTS: 22

Apocrine Adenoma

Categories: Cancer diseases, Skin diseases
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Aliases & Classifications for Apocrine Adenoma

MalaCards integrated aliases for Apocrine Adenoma:

Name: Apocrine Adenoma 11 14 71
Tubular Apocrine Adenoma 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3895
NCIt 49 C4168
SNOMED-CT 68 307596009
UMLS 71 C0334345

Summaries for Apocrine Adenoma

MalaCards based summary: Apocrine Adenoma, also known as tubular apocrine adenoma, is related to hidrocystoma and apocrine adenocarcinoma. An important gene associated with Apocrine Adenoma is PIP (Prolactin Induced Protein). Affiliated tissues include skin and breast, and related phenotype is Increased shRNA abundance (Z-score > 2).

Related Diseases for Apocrine Adenoma

Diseases related to Apocrine Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)
# Related Disease Score Top Affiliating Genes
1 hidrocystoma 31.2 PIP KRT8 KRT7 CEACAM5
2 apocrine adenocarcinoma 30.4 PIP KRT7 CEACAM5
3 hidradenoma 30.2 PIP KRT7 CEACAM5
4 eccrine acrospiroma 30.2 PIP KRT7 CEACAM5
5 ceruminoma 30.2 PIP KRT7
6 eccrine papillary adenoma 30.1 PIP KRT8 CEACAM5
7 syringocystadenoma papilliferum 30.1 PIP KRT7 ERAS CEACAM5
8 spiradenoma 29.8 PIP KRT7 CEACAM5
9 mammary paget's disease 29.8 PIP KRT7 CEACAM5
10 skin benign neoplasm 29.8 PLAG1 PIP KRT7
11 basal cell carcinoma 29.7 PIP KRT8 KRT7
12 mixed cell type cancer 29.6 PLAG1 KRT7 CEACAM5
13 breast ductal carcinoma 29.6 PIP KRT8 KRT7
14 syringoma 29.4 PLAG1 PIP KRT7 CEACAM5
15 sweat gland benign neoplasm 29.3 PLAG1 PIP KRT8 KRT7 CEACAM5
16 breast apocrine adenoma 11.3
17 adenoma 10.8
18 anal canal paget's disease 10.2 PIP KRT7
19 anal gland adenocarcinoma 10.2 PIP KRT7
20 bartholin's gland adenocarcinoma 10.2 PIP KRT7
21 anus adenocarcinoma 10.2 PIP KRT7
22 oncocytic breast carcinoma 10.2 PIP KRT7
23 anal canal adenocarcinoma 10.2 PIP KRT7
24 gastric signet ring cell adenocarcinoma 10.2 PIP KRT7
25 ceruminous adenocarcinoma 10.2 PIP KRT7
26 breast papillary carcinoma 10.2 PIP KRT7
27 eyelid carcinoma 10.2 PIP KRT7
28 breast mucinous carcinoma 10.2 PIP KRT7
29 meibomian cyst 10.2 PIP KRT7
30 erysipeloid 10.2 PIP KRT7
31 bartholin's gland disease 10.2 PIP KRT7
32 papillary cystadenocarcinoma 10.1 PIP KRT7
33 sebaceous breast carcinoma 10.1 PIP CEACAM5
34 vulvar eccrine porocarcinoma 10.1 PIP CEACAM5
35 cystic basal cell carcinoma 10.1 PIP KRT7
36 fox-fordyce disease 10.1 PIP CEACAM5
37 cystadenoma 10.1 KRT7 CEACAM5
38 lacrimal gland carcinoma 10.1 PIP KRT7
39 papillary adenoma 10.1 KRT7 CEACAM5
40 salivary gland adenoid cystic carcinoma 10.1 PIP KRT7
41 myoepithelial carcinoma 10.1 PLAG1 KRT7
42 leukoplakia of penis 10.1 KRT7 CEACAM5
43 urethral villous adenoma 10.1 KRT7 CEACAM5
44 villous adenoma 10.1 KRT7 CEACAM5
45 pancreatic foamy gland adenocarcinoma 10.1 KRT7 CEACAM5
46 pancreatic serous cystadenocarcinoma 10.1 KRT7 CEACAM5
47 aggressive digital papillary adenocarcinoma 10.1 KRT7 CEACAM5
48 ureter adenocarcinoma 10.1 KRT7 CEACAM5
49 malignant epithelial mesothelioma 10.1 KRT7 CEACAM5
50 vaginal tubulovillous adenoma 10.1 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Apocrine Adenoma:



Diseases related to Apocrine Adenoma

Symptoms & Phenotypes for Apocrine Adenoma

GenomeRNAi Phenotypes related to Apocrine Adenoma according to GeneCards Suite gene sharing:

25 (show all 18)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.66 SLC4A9
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.66 SLC4A9
3 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.66 KRT8
4 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.66 KRT7 KRT8
5 Increased shRNA abundance (Z-score > 2) GR00366-A-15 9.66 SLC4A9
6 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.66 SLC4A9
7 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.66 KRT8 SLC4A9
8 Increased shRNA abundance (Z-score > 2) GR00366-A-192 9.66 KRT7 KRT8
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.66 SLC4A9
10 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.66 SLC4A9
11 Increased shRNA abundance (Z-score > 2) GR00366-A-40 9.66 KRT8
12 Increased shRNA abundance (Z-score > 2) GR00366-A-68 9.66 KRT7
13 Increased shRNA abundance (Z-score > 2) GR00366-A-71 9.66 SLC4A9
14 Increased shRNA abundance (Z-score > 2) GR00366-A-72 9.66 KRT7
15 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.66 SLC4A9
16 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.66 KRT7 KRT8
17 Increased shRNA abundance (Z-score > 2) GR00366-A-91 9.66 KRT7
18 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.66 SLC4A9

Drugs & Therapeutics for Apocrine Adenoma

Search Clinical Trials, NIH Clinical Center for Apocrine Adenoma

Genetic Tests for Apocrine Adenoma

Anatomical Context for Apocrine Adenoma

Organs/tissues related to Apocrine Adenoma:

MalaCards : Skin, Breast

Publications for Apocrine Adenoma

Articles related to Apocrine Adenoma:

(show top 50) (show all 81)
# Title Authors PMID Year
1
Complex sweat gland hamartoma: A case report. 62
36323653 2022
2
Apocrine tubular adenoma on the palm: A case report. 62
34889245 2021
3
Trilogy Revisited: A Case Report of Co-Existing Nevus Sebaceous with Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma. 62
34430463 2021
4
Tubular apocrine adenoma: dermoscopic and in vivo reflectance confocal microscopic aspects. 62
31286506 2019
5
Tubular apocrine adenoma of the eyelid - A case report and literature review. 62
31686976 2019
6
Blaschkoid distribution of composite syringocystadenoma papilliferum and tubular apocrine adenoma without naevus sebaceous. 62
30251370 2019
7
[Palpebral hidrocystoma]. 62
31448032 2019
8
Apocrine Adenoma of the External Auditory Canal with Pseudoepitheliomatous Hyperplasia. 62
30915250 2019
9
Tubular apocrine adenoma: A rare and controversial tumor. 62
29863779 2019
10
Tubular Apocrine Adenoma on Vulva: An Unusual Location. 62
30258809 2018
11
Ectopic Tubular Papillary Apocrine Adenoma on the Eyelid: A Case Report of Misleading Clinical Presentation and Location. 62
30320096 2018
12
Umbilical Lesions: Clinicopathologic Features of 99 Tumors. 62
29484912 2018
13
BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin. 62
29241739 2018
14
Syringocystadenoma papilliferum combined with a tubular apocrine adenoma. 62
29166517 2017
15
Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma. 62
27772650 2016
16
[Tubulo-papillary apocrine adenoma in association with syringocystadenoma papilliferum]. 62
27693311 2016
17
Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma. 62
25037809 2014
18
Development of six tumors in a sebaceus nevus of jadassohn: report of a case. 62
24421851 2013
19
Fatal metastatic cutaneous squamous cell carcinoma evolving from a localized verrucous epidermal nevus. 62
24403890 2013
20
Syringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature. 62
23569386 2013
21
Case of tubular apocrine adenoma with follicular differentiation located on the trunk. 62
21906134 2012
22
Anal apocrine carcinoma: a case report and literature review. 62
22307230 2012
23
Syringocystadenoma papilliferum of the back combined with a tubular apocrine adenoma. 62
22148038 2011
24
A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria. 62
22355505 2011
25
Syringocystadenoma Papilliferum in Co-existence with Tubular Apocrine Adenoma on the Calf. 62
22148043 2011
26
Lipomatous apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. 62
21854651 2011
27
Squamous cell carcinoma, syringocystadenoma papilliferum and apocrine adenoma arising in a nevus sebaceus of Jadassohn. 62
21393932 2011
28
Tubular apocrine adenoma of the nose. 62
21252032 2011
29
A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum that Developed in a Nevus Sebaceus. 62
20711270 2010
30
Tubular apocrine adenoma: presentation in the vaginal introitus of an eight-year-old. 62
20537077 2010
31
Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. 62
18982051 2008
32
Congenital apocrine tumour: a rare scalp tumour. 62
18629773 2008
33
Apocrine adenoma of the breast. 62
18491794 2008
34
Non-operative breast pathology: apocrine lesions. 62
18042688 2007
35
Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists. 62
17519623 2007
36
Naevus sebaceus on the female breast accompanied with a tubular apocrine adenoma and a syringocystadenoma papilliferum. 62
17535243 2007
37
Apocrine adenoma of the breast coexistent with invasive carcinoma. 62
17936522 2007
38
Axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia. 62
17868540 2007
39
Mohs micrographic surgery for tubular apocrine adenoma. 62
17076735 2006
40
An unusual hamartoma of the folliculosebaceous-apocrine unit: a case report. 62
16640544 2006
41
Tubular adenoma of the skin with follicular and sebaceous differentiation: A report of two cases. 62
16625077 2006
42
Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. 62
16354370 2005
43
Eyelid reconstruction using a split eyelid flap after excision of a palpebral tumour in a Persian cat. 62
16119058 2005
44
Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. 62
15677547 2005
45
Tubular apocrine adenoma--an unusual eyelid tumour. 62
15105822 2005
46
A case of tubular apocrine adenoma with syringocystadenoma papilliferum arising in nevus sebaceus. 62
15235197 2004
47
Multifocal papillary apocrine adenoma arising in a systematized linear epidermal nevus. 62
15186052 2004
48
Three-millimeter apocrine adenoma in a man: a case report and review of the literature. 62
14567753 2003
49
Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor. 62
12641782 2003
50
Tubular apocrine adenoma in association with syringocystadenoma papilliferum. 62
12639465 2003

Variations for Apocrine Adenoma

Expression for Apocrine Adenoma

Search GEO for disease gene expression data for Apocrine Adenoma.

Pathways for Apocrine Adenoma

GO Terms for Apocrine Adenoma

Molecular functions related to Apocrine Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of skin epidermis GO:0030280 8.92 KRT8 KRT7

Sources for Apocrine Adenoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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