MCID: APC003
MIFTS: 27

Apocrine Adenoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Apocrine Adenoma

MalaCards integrated aliases for Apocrine Adenoma:

Name: Apocrine Adenoma 12 15 71
Tubular Apocrine Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3895
NCIt 49 C27527 C4168
SNOMED-CT 67 36318001
UMLS 71 C0334345

Summaries for Apocrine Adenoma

MalaCards based summary : Apocrine Adenoma, also known as tubular apocrine adenoma, is related to hidrocystoma and syringocystadenoma papilliferum. An important gene associated with Apocrine Adenoma is KRAS (KRAS Proto-Oncogene, GTPase), and among its related pathways/superpathways are Bladder cancer and Negative regulation of MAPK pathway. Affiliated tissues include breast, colon and thyroid.

Related Diseases for Apocrine Adenoma

Diseases related to Apocrine Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 220)
# Related Disease Score Top Affiliating Genes
1 hidrocystoma 31.8 PIP KRT7 CEACAM5
2 syringocystadenoma papilliferum 31.2 KRAS BRAF
3 adenoma 30.7 KRT7 KRAS BRAF
4 apocrine adenocarcinoma 30.5 PIP KRT7
5 eccrine papillary adenoma 30.2 PIP KRAS CEACAM5
6 syringoma 29.8 KRT7 CEACAM5
7 ceruminoma 29.8 PIP KRT7
8 hidradenoma 29.7 PIP KRT7 CEACAM5
9 mammary paget's disease 29.5 PIP KRT7
10 adenocarcinoma 29.1 KRT7 KRAS CEACAM5 BRAF
11 breast apocrine adenoma 12.4
12 selection of therapeutic option in colorectal cancer 10.3 KRAS BRAF
13 hyperplastic polyposis syndrome 10.2 KRAS BRAF
14 serous cystadenocarcinoma 10.2 KRAS BRAF
15 signet ring basal cell carcinoma 10.2 KRAS CEACAM5
16 rosai-dorfman disease 10.2 KRAS BRAF
17 immature teratoma of ovary 10.2 KRAS CEACAM5
18 struma ovarii 10.2 KRAS BRAF
19 descending colon cancer 10.2 KRAS CEACAM5
20 ascending colon cancer 10.2 KRAS CEACAM5
21 pulmonic stenosis 10.1 KRAS BRAF
22 bile duct cysts 10.1 KRAS CEACAM5
23 rectosigmoid cancer 10.1 KRAS CEACAM5
24 vulvar syringoma 10.1 PIP CEACAM5
25 vulvar eccrine porocarcinoma 10.1 PIP CEACAM5
26 nodular hidradenoma 10.1 PIP CEACAM5
27 fox-fordyce disease 10.1 PIP CEACAM5
28 rasopathy 10.1 KRAS BRAF
29 primary mediastinal b-cell lymphoma 10.1 KRAS BRAF
30 cecum carcinoma 10.1 KRAS CEACAM5
31 thyroid tumor 10.1 KRAS BRAF
32 vulvar benign neoplasm 10.0 PIP CEACAM5
33 costello syndrome 10.0 KRAS BRAF
34 pilomyxoid astrocytoma 10.0 KRAS BRAF
35 reproductive organ benign neoplasm 10.0 KRAS CEACAM5
36 ovarian cystadenocarcinoma 10.0 KRAS CEACAM5
37 differentiated thyroid carcinoma 10.0 KRAS BRAF
38 papillary adenoma 10.0 KRT7 KRAS
39 breast cancer 10.0
40 nevus, epidermal 10.0
41 schimmelpenning-feuerstein-mims syndrome 10.0
42 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.0
43 breast fibroadenoma 10.0
44 squamous cell carcinoma 10.0
45 basal cell carcinoma 10.0
46 breast ductal carcinoma 10.0
47 pleomorphic adenoma 10.0
48 spiradenoma 10.0
49 posttransplant acute limbic encephalitis 10.0
50 rare tumor 10.0

Graphical network of the top 20 diseases related to Apocrine Adenoma:



Diseases related to Apocrine Adenoma

Symptoms & Phenotypes for Apocrine Adenoma

Drugs & Therapeutics for Apocrine Adenoma

Search Clinical Trials , NIH Clinical Center for Apocrine Adenoma

Genetic Tests for Apocrine Adenoma

Anatomical Context for Apocrine Adenoma

MalaCards organs/tissues related to Apocrine Adenoma:

40
Breast, Colon, Thyroid, Ovary, Appendix, Skin, Liver

Publications for Apocrine Adenoma

Articles related to Apocrine Adenoma:

(show top 50) (show all 78)
# Title Authors PMID Year
1
Tubular apocrine adenoma: dermoscopic and in vivo reflectance confocal microscopic aspects. 61
31286506 2019
2
Tubular apocrine adenoma of the eyelid - A case report and literature review. 61
31686976 2019
3
Blaschkoid distribution of composite syringocystadenoma papilliferum and tubular apocrine adenoma without naevus sebaceous. 61
30251370 2019
4
Tubular apocrine adenoma: A rare and controversial tumor. 61
29863779 2019
5
Apocrine Adenoma of the External Auditory Canal with Pseudoepitheliomatous Hyperplasia. 61
30915250 2019
6
[Palpebral hidrocystoma]. 61
31448032 2019
7
Tubular Apocrine Adenoma on Vulva: An Unusual Location. 61
30258809 2018
8
Ectopic Tubular Papillary Apocrine Adenoma on the Eyelid: A Case Report of Misleading Clinical Presentation and Location. 61
30320096 2018
9
Umbilical Lesions: Clinicopathologic Features of 99 Tumors. 61
29484912 2018
10
BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin. 61
29241739 2018
11
Syringocystadenoma papilliferum combined with a tubular apocrine adenoma. 61
29166517 2017
12
Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma. 61
27772650 2016
13
[Tubulo-papillary apocrine adenoma in association with syringocystadenoma papilliferum]. 61
27693311 2016
14
Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma. 61
25037809 2014
15
Development of six tumors in a sebaceus nevus of jadassohn: report of a case. 61
24421851 2013
16
Fatal metastatic cutaneous squamous cell carcinoma evolving from a localized verrucous epidermal nevus. 61
24403890 2013
17
Syringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature. 61
23569386 2013
18
Case of tubular apocrine adenoma with follicular differentiation located on the trunk. 61
21906134 2012
19
Anal apocrine carcinoma: a case report and literature review. 61
22307230 2012
20
Syringocystadenoma papilliferum of the back combined with a tubular apocrine adenoma. 61
22148038 2011
21
Syringocystadenoma Papilliferum in Co-existence with Tubular Apocrine Adenoma on the Calf. 61
22148043 2011
22
A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria. 61
22355505 2011
23
Lipomatous apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. 61
21854651 2011
24
Tubular apocrine adenoma of the nose. 61
21252032 2011
25
Squamous cell carcinoma, syringocystadenoma papilliferum and apocrine adenoma arising in a nevus sebaceus of Jadassohn. 61
21393932 2011
26
A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum that Developed in a Nevus Sebaceus. 61
20711270 2010
27
Tubular apocrine adenoma: presentation in the vaginal introitus of an eight-year-old. 61
20537077 2010
28
Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. 61
18982051 2008
29
Congenital apocrine tumour: a rare scalp tumour. 61
18629773 2008
30
Apocrine adenoma of the breast. 61
18491794 2008
31
Non-operative breast pathology: apocrine lesions. 61
18042688 2007
32
Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists. 61
17519623 2007
33
Naevus sebaceus on the female breast accompanied with a tubular apocrine adenoma and a syringocystadenoma papilliferum. 61
17535243 2007
34
Axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia. 61
17868540 2007
35
Apocrine adenoma of the breast coexistent with invasive carcinoma. 61
17936522 2007
36
Mohs micrographic surgery for tubular apocrine adenoma. 61
17076735 2006
37
An unusual hamartoma of the folliculosebaceous-apocrine unit: a case report. 61
16640544 2006
38
Tubular adenoma of the skin with follicular and sebaceous differentiation: A report of two cases. 61
16625077 2006
39
Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. 61
16354370 2005
40
Eyelid reconstruction using a split eyelid flap after excision of a palpebral tumour in a Persian cat. 61
16119058 2005
41
Tubular apocrine adenoma--an unusual eyelid tumour. 61
15105822 2005
42
Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. 61
15677547 2005
43
A case of tubular apocrine adenoma with syringocystadenoma papilliferum arising in nevus sebaceus. 61
15235197 2004
44
Multifocal papillary apocrine adenoma arising in a systematized linear epidermal nevus. 61
15186052 2004
45
Three-millimeter apocrine adenoma in a man: a case report and review of the literature. 61
14567753 2003
46
Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor. 61
12641782 2003
47
Tubular apocrine adenoma in association with syringocystadenoma papilliferum. 61
12639465 2003
48
A case of ductal apocrine carcinoma in the left axilla with tubular apocrine adenoma in the right axilla. 61
12598714 2003
49
Verrucous carcinoma arising within syringocystadenoma papilliferum. 61
12458900 2002
50
Apocrine adenoma of the breast: diagnosis on large core needle biopsy. 61
11358045 2001

Variations for Apocrine Adenoma

Expression for Apocrine Adenoma

Search GEO for disease gene expression data for Apocrine Adenoma.

Pathways for Apocrine Adenoma

Pathways related to Apocrine Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.27 KRAS BRAF
2
Show member pathways
11.18 KRAS BRAF
3 11.1 KRAS BRAF
4 10.89 KRAS BRAF
5 10.74 KRAS BRAF
6 10.47 KRAS BRAF
7 10.05 KRAS BRAF

GO Terms for Apocrine Adenoma

Biological processes related to Apocrine Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.13 PIP KRAS BRAF
2 visual learning GO:0008542 8.62 KRAS BRAF

Sources for Apocrine Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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