Apocrine Adenoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Apocrine Adenoma

MalaCards integrated aliases for Apocrine Adenoma:

Name: Apocrine Adenoma ¹¹ ¹⁴ ⁷¹

Tubular Apocrine Adenoma ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:3895

NCIt ⁴⁹ C4168

SNOMED-CT ⁶⁸ 307596009

UMLS ⁷¹ C0334345

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Summaries for Apocrine Adenoma

MalaCards based summary: Apocrine Adenoma, also known as tubular apocrine adenoma, is related to hidrocystoma and apocrine adenocarcinoma. An important gene associated with Apocrine Adenoma is PIP (Prolactin Induced Protein). Affiliated tissues include skin and breast, and related phenotype is Increased shRNA abundance (Z-score > 2).

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Related Diseases for Apocrine Adenoma

Diseases related to Apocrine Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)

#	Related Disease	Score	Top Affiliating Genes
1	hidrocystoma	31.2	PIP KRT8 KRT7 CEACAM5
2	apocrine adenocarcinoma	30.4	PIP KRT7 CEACAM5
3	hidradenoma	30.2	PIP KRT7 CEACAM5
4	eccrine acrospiroma	30.2	PIP KRT7 CEACAM5
5	ceruminoma	30.2	PIP KRT7
6	eccrine papillary adenoma	30.1	PIP KRT8 CEACAM5
7	syringocystadenoma papilliferum	30.1	PIP KRT7 ERAS CEACAM5
8	spiradenoma	29.8	PIP KRT7 CEACAM5
9	mammary paget's disease	29.8	PIP KRT7 CEACAM5
10	skin benign neoplasm	29.8	PLAG1 PIP KRT7
11	basal cell carcinoma	29.7	PIP KRT8 KRT7
12	mixed cell type cancer	29.6	PLAG1 KRT7 CEACAM5
13	breast ductal carcinoma	29.6	PIP KRT8 KRT7
14	syringoma	29.4	PLAG1 PIP KRT7 CEACAM5
15	sweat gland benign neoplasm	29.3	PLAG1 PIP KRT8 KRT7 CEACAM5
16	breast apocrine adenoma	11.3
17	adenoma	10.8
18	anal canal paget's disease	10.2	PIP KRT7
19	anal gland adenocarcinoma	10.2	PIP KRT7
20	bartholin's gland adenocarcinoma	10.2	PIP KRT7
21	anus adenocarcinoma	10.2	PIP KRT7
22	oncocytic breast carcinoma	10.2	PIP KRT7
23	anal canal adenocarcinoma	10.2	PIP KRT7
24	gastric signet ring cell adenocarcinoma	10.2	PIP KRT7
25	ceruminous adenocarcinoma	10.2	PIP KRT7
26	breast papillary carcinoma	10.2	PIP KRT7
27	eyelid carcinoma	10.2	PIP KRT7
28	breast mucinous carcinoma	10.2	PIP KRT7
29	meibomian cyst	10.2	PIP KRT7
30	erysipeloid	10.2	PIP KRT7
31	bartholin's gland disease	10.2	PIP KRT7
32	papillary cystadenocarcinoma	10.1	PIP KRT7
33	sebaceous breast carcinoma	10.1	PIP CEACAM5
34	vulvar eccrine porocarcinoma	10.1	PIP CEACAM5
35	cystic basal cell carcinoma	10.1	PIP KRT7
36	fox-fordyce disease	10.1	PIP CEACAM5
37	cystadenoma	10.1	KRT7 CEACAM5
38	lacrimal gland carcinoma	10.1	PIP KRT7
39	papillary adenoma	10.1	KRT7 CEACAM5
40	salivary gland adenoid cystic carcinoma	10.1	PIP KRT7
41	myoepithelial carcinoma	10.1	PLAG1 KRT7
42	leukoplakia of penis	10.1	KRT7 CEACAM5
43	urethral villous adenoma	10.1	KRT7 CEACAM5
44	villous adenoma	10.1	KRT7 CEACAM5
45	pancreatic foamy gland adenocarcinoma	10.1	KRT7 CEACAM5
46	pancreatic serous cystadenocarcinoma	10.1	KRT7 CEACAM5
47	aggressive digital papillary adenocarcinoma	10.1	KRT7 CEACAM5
48	ureter adenocarcinoma	10.1	KRT7 CEACAM5
49	malignant epithelial mesothelioma	10.1	KRT7 CEACAM5
50	vaginal tubulovillous adenoma	10.1	KRT7 CEACAM5

Graphical network of the top 20 diseases related to Apocrine Adenoma:

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Symptoms & Phenotypes for Apocrine Adenoma

GenomeRNAi Phenotypes related to Apocrine Adenoma according to GeneCards Suite gene sharing:

²⁵ (show all 18)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-113	9.66	SLC4A9
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-115	9.66	SLC4A9
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-126	9.66	KRT8
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-135	9.66	KRT7 KRT8
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-15	9.66	SLC4A9
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-168	9.66	SLC4A9
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-180	9.66	KRT8 SLC4A9
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-192	9.66	KRT7 KRT8
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-25	9.66	SLC4A9
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-35	9.66	SLC4A9
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-40	9.66	KRT8
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-68	9.66	KRT7
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-71	9.66	SLC4A9
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-72	9.66	KRT7
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-73	9.66	SLC4A9
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-74	9.66	KRT7 KRT8
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-91	9.66	KRT7
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-93	9.66	SLC4A9

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Drugs & Therapeutics for Apocrine Adenoma

Search Clinical Trials, NIH Clinical Center for Apocrine Adenoma

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Genetic Tests for Apocrine Adenoma

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Anatomical Context for Apocrine Adenoma

Organs/tissues related to Apocrine Adenoma:

MalaCards : Skin, Breast

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Publications for Apocrine Adenoma

Articles related to Apocrine Adenoma:

(show top 50) (show all 81)

#	Title	Authors	PMID	Year
1	Complex sweat gland hamartoma: A case report. ⁶²	Skopec Z...Liu V	36323653	2022
2	Apocrine tubular adenoma on the palm: A case report. ⁶²	Choi J...Jung SN	34889245	2021
3	Trilogy Revisited: A Case Report of Co-Existing Nevus Sebaceous with Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma. ⁶²	Bardia A...Vinay K	34430463	2021
4	Tubular apocrine adenoma: dermoscopic and in vivo reflectance confocal microscopic aspects. ⁶²	Lupu M...Ardigo M	31286506	2019
5	Tubular apocrine adenoma of the eyelid - A case report and literature review. ⁶²	Eiger-Moscovich M...Milman T	31686976	2019
6	Blaschkoid distribution of composite syringocystadenoma papilliferum and tubular apocrine adenoma without naevus sebaceous. ⁶²	Khullar G...Mann KK	30251370	2019
7	[Palpebral hidrocystoma]. ⁶²	Agharbi FZ	31448032	2019
8	Apocrine Adenoma of the External Auditory Canal with Pseudoepitheliomatous Hyperplasia. ⁶²	Ohki M...Kikuchi S	30915250	2019
9	Tubular apocrine adenoma: A rare and controversial tumor. ⁶²	Cortes-Pinto C...Casanova Seuma JM	29863779	2019
10	Tubular Apocrine Adenoma on Vulva: An Unusual Location. ⁶²	Jain S...Malkar BV	30258809	2018
11	Ectopic Tubular Papillary Apocrine Adenoma on the Eyelid: A Case Report of Misleading Clinical Presentation and Location. ⁶²	Abbeel L...Van Ginderdeuren R	30320096	2018
12	Umbilical Lesions: Clinicopathologic Features of 99 Tumors. ⁶²	Yan L...Gattuso P	29484912	2018
13	BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin. ⁶²	Liau JY...Yuan CT	29241739	2018
14	Syringocystadenoma papilliferum combined with a tubular apocrine adenoma. ⁶²	Leda LDSB...Houly RLS	29166517	2017
15	Tubular Apocrine Adenoma in Association with an Apocrine Hidrocystoma. ⁶²	Raven ML...Lucarelli MJ	27772650	2016
16	[Tubulo-papillary apocrine adenoma in association with syringocystadenoma papilliferum]. ⁶²	Ayadi L...Gouiaa N	27693311	2016
17	Tubular apocrine adenoma clinically and dermoscopically mimicking basal cell carcinoma. ⁶²	Ito T...Shimizu H	25037809	2014
18	Development of six tumors in a sebaceus nevus of jadassohn: report of a case. ⁶²	Gozel S...Yikilkan H	24421851	2013
19	Fatal metastatic cutaneous squamous cell carcinoma evolving from a localized verrucous epidermal nevus. ⁶²	Riad H...Hussain K	24403890	2013
20	Syringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature. ⁶²	Xu D...Jin K	23569386	2013
21	Case of tubular apocrine adenoma with follicular differentiation located on the trunk. ⁶²	Nakagomi D...Shimada S	21906134	2012
22	Anal apocrine carcinoma: a case report and literature review. ⁶²	Hall BJ...Liu T	22307230	2012
23	Syringocystadenoma papilliferum of the back combined with a tubular apocrine adenoma. ⁶²	Lee HJ...Lee JD	22148038	2011
24	A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria. ⁶²	Abudu EK...Obi-Ihesie A	22355505	2011
25	Syringocystadenoma Papilliferum in Co-existence with Tubular Apocrine Adenoma on the Calf. ⁶²	Yoon JH...Seo SH	22148043	2011
26	Lipomatous apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. ⁶²	Su TC...Chen ML	21854651	2011
27	Squamous cell carcinoma, syringocystadenoma papilliferum and apocrine adenoma arising in a nevus sebaceus of Jadassohn. ⁶²	Malhotra P...Singh A	21393932	2011
28	Tubular apocrine adenoma of the nose. ⁶²	Mitsuishi T...Kawana S	21252032	2011
29	A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum that Developed in a Nevus Sebaceus. ⁶²	Kim MS...Son SJ	20711270	2010
30	Tubular apocrine adenoma: presentation in the vaginal introitus of an eight-year-old. ⁶²	Ross I...Shwayder T	20537077	2010
31	Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. ⁶²	Akcay EK...Gumus M	18982051	2008
32	Congenital apocrine tumour: a rare scalp tumour. ⁶²	Goodden JR...Smith MF	18629773	2008
33	Apocrine adenoma of the breast. ⁶²	Cashell AW	18491794	2008
34	Non-operative breast pathology: apocrine lesions. ⁶²	Wells CA...El-Ayat GA	18042688	2007
35	Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists. ⁶²	Kazakov DV...Zelger B	17519623	2007
36	Naevus sebaceus on the female breast accompanied with a tubular apocrine adenoma and a syringocystadenoma papilliferum. ⁶²	Yamane N...Osawa R	17535243	2007
37	Apocrine adenoma of the breast coexistent with invasive carcinoma. ⁶²	Bezic J...Gunjaca G	17936522	2007
38	Axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia. ⁶²	Bujas T...Tomas D	17868540	2007
39	Mohs micrographic surgery for tubular apocrine adenoma. ⁶²	Martinelli PT...Nelson BR	17076735	2006
40	An unusual hamartoma of the folliculosebaceous-apocrine unit: a case report. ⁶²	Kazakov DV...Michal M	16640544	2006
41	Tubular adenoma of the skin with follicular and sebaceous differentiation: A report of two cases. ⁶²	Kazakov DV...Michal M	16625077	2006
42	Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. ⁶²	Lee CK...Cho YS	16354370	2005
43	Eyelid reconstruction using a split eyelid flap after excision of a palpebral tumour in a Persian cat. ⁶²	Hagard GM	16119058	2005
44	Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. ⁶²	MacNeill KN...Ghazarian D	15677547	2005
45	Tubular apocrine adenoma--an unusual eyelid tumour. ⁶²	Stokes J...Dhillon B	15105822	2005
46	A case of tubular apocrine adenoma with syringocystadenoma papilliferum arising in nevus sebaceus. ⁶²	Ahn BK...Kim YC	15235197	2004
47	Multifocal papillary apocrine adenoma arising in a systematized linear epidermal nevus. ⁶²	Rechdouni A...Vadmal MS	15186052	2004
48	Three-millimeter apocrine adenoma in a man: a case report and review of the literature. ⁶²	Pasquale-Styles MA...Milikowski C	14567753	2003
49	Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor. ⁶²	Hsu PJ...Huang CJ	12641782	2003
50	Tubular apocrine adenoma in association with syringocystadenoma papilliferum. ⁶²	Aktepe F...Dilek FH	12639465	2003

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Genes for Apocrine Adenoma

Genes related to Apocrine Adenoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PIP	Prolactin Induced Protein	Protein Coding	6.49	DISEASES inferred ¹⁴
2	SLC4A9	Solute Carrier Family 4 Member 9	Protein Coding	5.39	DISEASES inferred ¹⁴
3	KRT7	Keratin 7	Protein Coding	5.32	DISEASES inferred ¹⁴
4	PLAG1	PLAG1 Zinc Finger	Protein Coding	5.29	DISEASES inferred ¹⁴
5	KRT8	Keratin 8	Protein Coding	5.2	DISEASES inferred ¹⁴
6	ERAS	ES Cell Expressed Ras	Protein Coding	5	DISEASES inferred ¹⁴
7	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	4.98	DISEASES inferred ¹⁴

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Variations for Apocrine Adenoma

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Expression for Apocrine Adenoma

Search GEO for disease gene expression data for Apocrine Adenoma.

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Pathways for Apocrine Adenoma

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GO Terms for Apocrine Adenoma

Molecular functions related to Apocrine Adenoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	structural constituent of skin epidermis	GO:0030280	8.92	KRT8 KRT7

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Sources for Apocrine Adenoma

¹ BitterDB

² CDC

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²⁶ GEO DataSets

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³¹ ICD10

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³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

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³⁹ MalaCards

⁴⁰ MedGen

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⁴⁷ NCBI Bookshelf

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⁵¹ NIH Clinical Center

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⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

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⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: APC003 MIFTS: 22	Apocrine Adenoma Categories: Cancer diseases, Skin diseases	Data Licensing For inquiries, contact: [email protected]
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