MCID: APP003
MIFTS: 40

Appendiceal Neoplasm

Categories: Cancer diseases, Gastrointestinal diseases
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Aliases & Classifications for Appendiceal Neoplasm

Summaries for Appendiceal Neoplasm

MalaCards based summary: Appendiceal Neoplasm, also known as malignant neoplasm of appendix vermiformis, is related to appendix cancer and pseudomyxoma peritonei. An important gene associated with Appendiceal Neoplasm is GNAS (GNAS Complex Locus), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and CCR3 Pathway in Eosinophils. The drugs Cyclophosphamide and Durvalumab have been mentioned in the context of this disorder. Affiliated tissues include appendix, small intestine and colon, and related phenotypes are Reduced mammosphere formation and neoplasm

Related Diseases for Appendiceal Neoplasm

Diseases related to Appendiceal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 398)
# Related Disease Score Top Affiliating Genes
1 appendix cancer 30.7 SATB2 PEX19 KRT7 KRAS HRAS GNAS
2 pseudomyxoma peritonei 30.0 KRT7 KRAS GNAS CEACAM5 CDX2
3 anal canal carcinoma 29.8 KRT7 CEACAM5 CDX2
4 intestinal obstruction 29.8 KRT7 CEACAM5 CDX2
5 cystadenocarcinoma 29.7 KRT7 KRAS CEACAM5
6 krukenberg carcinoma 29.7 SATB2 KRT7 CEACAM5 CDX2
7 rectum cancer 29.7 KRAS HRAS CEACAM5
8 cystadenoma 29.6 KRT7 GNAS CHGA CEACAM5
9 ovarian cystadenocarcinoma 29.5 KRAS HRAS GNAS CEACAM5
10 colon adenocarcinoma 29.5 KRAS HRAS GNAS CEACAM5
11 tubular adenocarcinoma 29.4 KRT7 CHGA CEACAM5 CDX2
12 intestinal benign neoplasm 29.4 KRAS HRAS CEACAM5 CDX2
13 mucinous adenocarcinoma 29.1 KRT7 KRAS HRAS GNAS CEACAM5 CDX2
14 rectal benign neoplasm 29.1 KRT7 KRAS HRAS CEACAM5 CDX2
15 anus cancer 29.1 KRT7 KRAS HRAS CEACAM5 CDX2
16 colonic benign neoplasm 29.0 KRT7 KRAS HRAS CEACAM5 CDX2
17 villous adenoma 28.9 KRT7 KRAS HRAS GNAS CEACAM5 CDX2
18 ovary adenocarcinoma 28.9 KRT7 KRAS HRAS GNAS CEACAM5 CDX2
19 colorectal adenocarcinoma 28.9 SATB2 KRT7 KRAS HRAS CEACAM5 CDX2
20 adenoma 28.8 KRT7 KRAS HRAS GNAS CHGA CDX2
21 mucinous cystadenocarcinoma 28.7 MIR4328 KRT7 KRAS HRAS CEACAM5 CDX2
22 adenocarcinoma 28.5 KRT7 KRAS HRAS CHGA CEACAM5 CDX2
23 signet ring cell adenocarcinoma 28.4 KRT7 KRAS HRAS CHGA CEACAM5 CDX2
24 appendix adenocarcinoma 28.0 SATB2 KRT7 KRAS HRAS GNAS CHGA
25 appendix carcinoid tumor 11.1
26 appendicitis 10.4
27 ovarian cyst 10.3 GNAS CEACAM5
28 mucinous cystadenocarcinoma of pancreas 10.3 SATB2 CEACAM5
29 laryngeal mucoepidermoid carcinoma 10.3 CEACAM5 CDX2
30 parosteal osteosarcoma 10.3 SATB2 GNAS
31 thymus adenocarcinoma 10.3 CEACAM5 CDX2
32 ovarian cystadenoma 10.2 KRT7 CEACAM5
33 gallbladder carcinoma in situ 10.2 CEACAM5 CDX2
34 peripheral osteosarcoma 10.2 SATB2 GNAS
35 leukoplakia of penis 10.2 KRT7 CEACAM5
36 trachea carcinoma 10.2 KRT7 CEACAM5
37 urethral villous adenoma 10.2 KRT7 CEACAM5
38 carcinoid syndrome 10.2
39 goblet cell carcinoid 10.2
40 pancreatic serous cystadenocarcinoma 10.2 KRT7 CEACAM5
41 aggressive digital papillary adenocarcinoma 10.2 KRT7 CEACAM5
42 cutaneous mucoepidermoid carcinoma 10.2 KRT7 CEACAM5
43 malignant epithelial mesothelioma 10.2 KRT7 CEACAM5
44 malignant spiradenoma 10.2 KRT7 CEACAM5
45 atypical polypoid adenomyoma 10.2 SATB2 CDX2
46 spiradenoma 10.2 KRT7 CEACAM5
47 eccrine porocarcinoma 10.2 KRT7 CEACAM5
48 adenosquamous bile duct carcinoma 10.2 KRT7 CEACAM5
49 ureter squamous cell carcinoma 10.2 KRT7 CEACAM5
50 apocrine adenoma 10.2 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Appendiceal Neoplasm:



Diseases related to Appendiceal Neoplasm

Symptoms & Phenotypes for Appendiceal Neoplasm

GenomeRNAi Phenotypes related to Appendiceal Neoplasm according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.02 CHGA GNAS HRAS KRAS KRT7

MGI Mouse Phenotypes related to Appendiceal Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.35 CDX2 CEACAM5 GNAS HRAS KRAS
2 endocrine/exocrine gland MP:0005379 9.17 CDX2 CEACAM5 CHGA GNAS HRAS KRAS

Drugs & Therapeutics for Appendiceal Neoplasm

Drugs for Appendiceal Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 66)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 1, Phase 2 50-18-0, 6055-19-2 2907
2
Durvalumab Approved, Investigational Phase 1, Phase 2 1428935-60-7
3
Thalidomide Approved, Investigational, Withdrawn Phase 2 50-35-1 5426
4
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
5
Levoleucovorin Approved, Experimental, Investigational Phase 2 68538-85-2, 58-05-9, 73951-54-9 149436 6006
6
Capecitabine Approved, Investigational Phase 2 154361-50-9 60953
7
Melphalan Approved Phase 2 148-82-3 4053 460612
8
Floxuridine Approved Phase 2 50-91-9 5790
9
Cetuximab Approved Phase 1, Phase 2 205923-56-4
10
Dexlansoprazole Approved, Investigational Phase 2 138530-94-6 9578005
11
Clarithromycin Approved Phase 2 81103-11-9 84029
12
Carbamide peroxide Approved Phase 2 124-43-6
13
Lansoprazole Approved, Investigational Phase 2 103577-45-3 3883
14
Amoxicillin Approved, Vet_approved Phase 2 26787-78-0 33613
15
Oxaliplatin Approved, Investigational Phase 2 61825-94-3 43805 11947679 6857599
16
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
17
Nintedanib Approved Phase 2 656247-17-5 135423438 9809715
18
Nivolumab Approved Phase 2 946414-94-4
19
Ipilimumab Approved Phase 2 477202-00-9
20
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
21
Exatecan Investigational Phase 1, Phase 2 171335-80-1 18546929 151115
22 Cola Phase 2
23 Angiogenesis Inhibitors Phase 2
24 Mitomycins Phase 2
25 Tubulin Modulators Phase 2
26 Antimitotic Agents Phase 2
27 Albumin-Bound Paclitaxel Phase 2
28 Alkylating Agents Phase 2
29 Antidotes Phase 2
30 Protective Agents Phase 2
31 Antimetabolites Phase 2
32 Immunosuppressive Agents Phase 2
33 Immunologic Factors Phase 2
34 Antineoplastic Agents, Alkylating Phase 2
35 Micronutrients Phase 2
36 Folate Phase 2
37 Vitamins Phase 2
38 Trace Elements Phase 2
39 Vitamin B9 Phase 2
40 Vitamin B Complex Phase 2
41 Anti-Infective Agents Phase 2
42 Gastrointestinal Agents Phase 2
43 Cytochrome P-450 Enzyme Inhibitors Phase 2
44 Cytochrome P-450 CYP3A Inhibitors Phase 2
45 Anti-Ulcer Agents Phase 2
46 Proton Pump Inhibitors Phase 2
47 Antibiotics, Antitubercular Phase 2
48 Anti-Bacterial Agents Phase 2
49 Antacids Phase 2
50 Antineoplastic Agents, Immunological Phase 2

Interventional clinical trials:

(show all 36)
# Name Status NCT ID Phase Drugs
1 Repetitive Electrostatic Pressurised Intraperitoneal Aerosol Chemotherapy With Oxaliplatin (ePIPAC-OX) as a Palliative Monotherapy for Isolated Unresectable Colorectal Peritoneal Metastases: Protocol of a Multicentre, Open-label, Single-arm, Phase II Study (CRC-PIPAC) Completed NCT03246321 Phase 2
2 Single Arm Study Treating Patients of Peritoneal Surface Malignancy (Colorectal, Appendical, Pseudomyxoma, Gastric) With Cytoreductive Surgery and Hyperthermic Intraperitoneal Mitomycin-C Completed NCT02040142 Phase 2 Mitomycin C
3 A Phase 1/2 Dose Escalation Study With Expansion Cohorts to Investigate the Safety, Biologic and Anti-tumor Activity of ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies Completed NCT02963831 Phase 1, Phase 2 Durvalumab
4 Phase II Trial of Adjuvant Thalidomide Following Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemotherapy for Peritoneal Carcinomatosis or Adenomucinosis From Colorectal/Appendiceal Cancer Completed NCT00310076 Phase 2 thalidomide
5 Phase II Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Ovarian, or Other Gynecologic Primary Cancer Recruiting NCT05185947 Phase 2 Paclitaxel;Nilotinib
6 Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes Recruiting NCT04907643 Phase 2
7 A Phase 1/2 Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors Recruiting NCT04902872 Phase 1, Phase 2 CBX-12
8 Surufatinib and Sintilimab in Combination With Capecitabine in Patients With Previously Treated Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma : a Single-arm, a Single-center , Phase 2 Trial Recruiting NCT05472948 Phase 2 Surufatinib
9 Phase II Single-Blind Randomized Trial Comparing Morbidity of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis Recruiting NCT03073694 Phase 2 Mitomycin c;Melphalan
10 ICARuS (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Multi-center, Randomized Phase II Trial of Early Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis Recruiting NCT01815359 Phase 2 HIPEC with Mitomycin-C;EPIC with FUDR and Leucovorin
11 A Phase Ib/II Trial of JAB-21822 in Combination With Cetuximab in Patients With Advanced Colorectal Cancer, Small Intestine Cancer and Appendiceal Cancer With KRAS G12C Mutation Recruiting NCT05194995 Phase 1, Phase 2 JAB-21822;Cetuximab
12 Clinical Trial to Define the Effect of Perioperative H. Pylori Eradication With Antibiotic Treatment on Long Term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin Undergoing Cytoreductive Surgery/Hyperthermic Intraperitoneal Chemotherapy Active, not recruiting NCT02387203 Phase 2 PrevPac (Prevacid, Amoxicillin, Clarithromycin)
13 Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery With Intraperitoneal Chemohyperthermia Using Oxaliplatin Plus Irinotecan Terminated NCT00180960 Phase 2 Oxaliplatin and irinotecan
14 LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma Terminated NCT03287947 Phase 2 nintedanib
15 A Phase II Study of Nivolumab and Ipilimumab in Mucinous Colorectal and Appendiceal Tumors Terminated NCT03693846 Phase 2 Nivolumab;Ipilimumab
16 Phase I Trial of Intraperitoneal Oxaliplatin in Combination With Intravenous FOLFIRI (5-fluorouracil, Leucovorin and Irinotecan) for Peritoneal Carcinomatosis From Colorectal and Appendiceal Cancer Completed NCT02833753 Phase 1 Oxaliplatin
17 Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies Recruiting NCT04847063 Phase 1 Mitomycin C;Cisplatin;Doxorubicin;Oxaliplatin;5-Fluorouracil;Sodium Thiosulfate
18 Safety and Efficacy of Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Ovarian, Uterine, Appendiceal, Colorectal, and Gastric Cancer Patients With Peritoneal Carcinomatosis (PC) Recruiting NCT04329494 Phase 1 Cisplatin;Doxorubicin;Fluorouracil;Irinotecan;Leucovorin;Mitomycin;Oxaliplatin
19 Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer: a Phase I Study Not yet recruiting NCT05277766 Phase 1 PIPAC with Nal-IRI
20 Phase I Trial of Intraperitoneal Oxaliplatin in Combination With Intravenous mFOLFIRI for Peritoneal Carcinomatosis From Colorectal and Appendiceal Cancer Terminated NCT04158349 Phase 1 Oxaliplatin;mFOLFIRI
21 Selective Rather Than Routine Histopathological Examination Following Appendectomy and Cholecystectomy; the FANCY Study. Unknown status NCT03510923
22 Multicenter, International Online Documentation of Indications and Results of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC Und PITAC) for Treating Malignant Peritoneal and Pleural Diseases Unknown status NCT03210298
23 A Survey of the Knowledge, Attitudes, and Practice of Surgeons Toward Nutrition Support in HIPEC Patients Completed NCT02374411
24 Surgical Outcome and Predictors of Overall Survival of Stage I-III Appendiceal Adenocarcinoma; a National Cancer Database Analysis Completed NCT05452382
25 Distant Metastases and Long-Term Survival After Complete Resection of Neuroendocrine Tumors of the Appendix: An International Multicenter Study Completed NCT03852693
26 Trial of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Primary Peritoneal Cancers and Secondary Peritoneal Cancers From Stomach, Colorectal, Appendiceal, and/or Gynecological Origins Completed NCT03604653 Mitomycin c;CDDP 50;CDDP 75;Doxorubicin
27 GI 1549: PROGRAMS TO SUPPORT YOU DURING CHEMOTHERAPY (PRO-YOU) A Randomized Controlled Pilot Study of Yoga Compared to an Attention Control in Patients Receiving Chemotherapy Completed NCT02489422
28 A Cohort Study of the Gastrointestinal Microbiome in Appendiceal Cancer With Peritoneal Spread Recruiting NCT02599116
29 A Phase II Trial to Analyze Clinical and Pharmacological Properties for Severe Neutropenia After Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy Using Mitomycin-C Recruiting NCT05513183
30 The Registry of Oncology Outcomes Associated With Testing and Treatment (ROOT) Recruiting NCT04028479 Systemic Treatment (T)
31 5-hydroxymethylation Signatures in Plasma Circulating Cell-free DNA as Markers for Tumor Burden and Recurrence in Appendiceal and Colorectal Peritoneal Metastasis Recruiting NCT04157322
32 The PANO Trial: Perioperative Exercise and Nutrition Optimisation Prehabilitation in Cancer Patients With Peritoneal Malignancy Recruiting NCT05305820
33 A Pragmatic, Single-Arm Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy Recruiting NCT04526886
34 Characterisation of Appendiceal Cancer by Genomic and Transcriptomic Analysis and Correlation With Clinical Outcomes Not yet recruiting NCT05364788
35 The Prevalence of Appendiceal Tumours in Patients Presenting With a Periappendicular Abscess - A Nationwide Prospective Cohort Study Not yet recruiting NCT04634448
36 Justification of Incidental Appendectomy With Respect to Pathohistological Findings Not yet recruiting NCT05202600

Search NIH Clinical Center for Appendiceal Neoplasm

Genetic Tests for Appendiceal Neoplasm

Anatomical Context for Appendiceal Neoplasm

Organs/tissues related to Appendiceal Neoplasm:

MalaCards : Appendix, Small Intestine, Colon, Lymph Node, Ovary, T Cells, Liver

Publications for Appendiceal Neoplasm

Articles related to Appendiceal Neoplasm:

(show top 50) (show all 588)
# Title Authors PMID Year
1
Validation of a Nomogram to Predict Recurrence in Patients with Mucinous Neoplasms of the Appendix with Peritoneal Dissemination After Cytoreductive Surgery and HIPEC. 62
35876926 2022
2
Appendiceal Goblet Cell Adenocarcinoma: A Historically Informed Reading of 6 Cases. 62
35142802 2022
3
Acute lower gastrointestinal bleeding due to low-grade mucinous neoplasm of appendix. 62
33274692 2022
4
ASO Visual Abstract: Socioeconomic Barriers to CRS HIPEC for Appendiceal Cancer within a Regional Academic Hospital System. 62
35798897 2022
5
ASO Author Reflections: CRS/HIPEC Cannot be Done-Now what? Systemic Chemotherapy in Mucinous Appendiceal Cancer. 62
35644859 2022
6
Socioeconomic Barriers to CRS HIPEC for Appendiceal Cancer within a Regional Academic Hospital System. 62
35639293 2022
7
Systemic Chemotherapy for High-Grade Mucinous Appendiceal Cancer with Peritoneal Spread After Unsuccessful CRS/HIPEC. 62
35641710 2022
8
Do Lymph Node Metastases Matter in Appendiceal Cancer with Peritoneal Carcinomatosis? A US HIPEC Collaborative Study. 62
36258061 2022
9
Incomplete cytoreduction with peritoneal metastases from appendiceal mucinous neoplasms. 62
36102369 2022
10
Is Cytoreductive Surgery-Hyperthermic Intraperitoneal Chemotherapy Still Indicated in Patients With Extraperitoneal Disease? 62
35525209 2022
11
Second-look Surgery for Appendiceal High Grade and Colorectal Cancers Following Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC). 62
36099142 2022
12
Primary Appendiceal Adenocarcinoma Masquerading as Acute Appendicitis: A Case Report. 62
36225475 2022
13
Treatment Patterns of Real-World Patients with TRK Fusion Cancer Treated by US Community Oncologists. 62
36089643 2022
14
Amyand's hernia: which oncologic risk can be hidden in the sac? 62
36134747 2022
15
Initial Experience of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Baltic Country Center. 62
36233421 2022
16
Incidental Appendiceal Tumors During Appendectomy: A Nineteen-Year Retrospective Review at a Municipal Hospital. 62
36074007 2022
17
An ex-vivo organotypic culture platform for functional interrogation of human appendiceal cancer reveals a prominent and heterogenous immunological landscape. 62
36067351 2022
18
Adjuvant chemotherapy for high-grade appendiceal cancer after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. 62
36253240 2022
19
Accidental discovery of appendiceal carcinoma during gynecological surgery: A case report. 62
36158468 2022
20
An unusual case of appendicitis due to appendiceal neuroendocrine tumor in a patient: A case report. 62
35837025 2022
21
Short and long-term outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for colorectal and appendiceal cancer peritoneal metastasis: Propensity score-matched comparison between laparoscopy vs. open approaches. 62
35430126 2022
22
Revisiting the necessity for routine appendectomies in mucinous neoplasms of the ovary: An evaluation of 460 mucinous ovarian tumors. 62
35439697 2022
23
Clinicopathological features of appendiceal goblet cell adenocarcinoma in Japan: a multicenter retrospective study. 62
35913635 2022
24
Signet-ring cell carcinoma of the appendix with ganglioneuromatosis: a case report. 62
35927360 2022
25
Bone metaplasia of the appendix presented with clinical and computed tomography signs of acute appendicitis managed with laparoscopic appendectomy. 62
35915527 2022
26
Cerebral Metastases in Appendiceal Cancer: Comprehensive Review and Report of Rare Medullary Carcinoma Histology. 62
35929119 2022
27
Early postoperative intraperitoneal chemotherapy (EPIC) following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in 632 patients with pseudomyxoma peritonei of appendiceal origin: A single institution experience. 62
35168851 2022
28
Mucinous appendiceal neoplasms and pseudomyxoma peritonei: Morphological and clinical findings, differential diagnosis, and prognosis. 62
35900483 2022
29
Lymph node positive pseudomyxoma peritonei. 62
35941031 2022
30
Incidental Finding of Appendiceal Mucinous Neoplasm After Trauma: A Case Report. 62
35836463 2022
31
After thirty years of experience with early postoperative intraperitoneal 5-fluorouracil now saying goodbye. 62
35398760 2022
32
Prognostic Impact of Pathology, Cytoreduction, and Tumor Markers in Pseudomyxoma Peritonei. 62
35123285 2022
33
Iterative Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Recurrent Mucinous Adenocarcinoma of the Appendix. 62
35133518 2022
34
ASO Author Reflections: If at First You Don't Succeed, Try, Try Again: Iterative CRS/HIPEC for Recurrent Mucinous Appendix Cancer. 62
35015184 2022
35
ASO Visual Abstract: Systemic Chemotherapy in High-Grade Mucinous Appendiceal Cancer with Peritoneal Spread after Unsuccessful Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC). 62
35731357 2022
36
Survival and prognostic factors for postoperative primary appendiceal cancer: a retrospective cohort study based on the Surveillance, Epidemiology, and End Results database. 62
35837159 2022
37
Appendiceal Cancer in the National Cancer Database: Increasing Frequency, Decreasing Age, and Shifting Histology. 62
35703801 2022
38
The association between appendicitis severity and patient age with appendiceal neoplasm histology-a population-based study. 62
35474547 2022
39
A Canadian single-centre experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for abdominal malignancies. 62
35580884 2022
40
Incidental Findings of Appendiceal Diverticulitis Presenting as Acute Appendicitis. 62
34937429 2022
41
Case series on high grade appendiceal cancer with peritoneal and liver carcinomatosis undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). 62
35398783 2022
42
Re: Tuberculosis, still the great mimicker: a rare case of disseminated tuberculosis masquerading as appendiceal cancer with peritoneal carcinomatosis. 62
35434958 2022
43
A case report of appendiceal adenocarcinoma without gastrointestinal evidence mimicking primary ovarian cancer. 62
35387517 2022
44
Utility of Neoadjuvant Chemotherapy for Peritoneal Carcinomatosis Secondary to High-Grade Appendiceal Neoplasms for Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy. 62
35022900 2022
45
ASO Visual Abstract: Utility of Neoadjuvant Chemotherapy for Peritoneal Carcinomatosis Secondary to High-Grade Appendiceal Neoplasms for Patients Undergoing Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy. 62
35006505 2022
46
ASO Author Reflections: Neoadjuvant Chemotherapy for High-Grade Appendiceal Neoplasms Before Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy, Closer to Evidence-Based Practice? 62
35001235 2022
47
Validating the PSOGI classification of peritoneal disease from non-carcinoid epithelial appendiceal neoplasms in the curative and palliative setting: an observational retrospective study. 62
35557579 2022
48
ASO Author Reflections: Establishing Novel Molecular Subtypes of Appendiceal Cancer. 62
34708274 2022
49
ASO Visual Abstract: Establishing Novel Molecular Subtypes of Appendiceal Cancer. 62
34718914 2022
50
Controversies in appendiceal pathology: mucinous and goblet cell neoplasms. 62
34836648 2022

Variations for Appendiceal Neoplasm

Expression for Appendiceal Neoplasm

Search GEO for disease gene expression data for Appendiceal Neoplasm.

Pathways for Appendiceal Neoplasm

Pathways related to Appendiceal Neoplasm according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.87 KRAS HRAS CEACAM5
2
Show member pathways
11.71 KRAS HRAS GNAS
3
Show member pathways
11.49 KRAS HRAS GNAS
4 11.38 KRAS HRAS CHGA
5
Show member pathways
11.18 KRAS HRAS GNAS
6 11.13 KRAS HRAS
7
Show member pathways
11.07 KRAS HRAS
8 11.03 KRAS HRAS
9 11.02 KRAS HRAS
10
Show member pathways
11 KRAS HRAS
11 10.97 KRAS HRAS
12 10.94 KRAS HRAS
13
Show member pathways
10.93 KRAS HRAS
14 10.84 KRAS HRAS
15 10.76 HRAS KRAS
16 10.73 HRAS KRAS
17
Show member pathways
10.58 KRAS HRAS GNAS
18
Show member pathways
10.4 KRAS HRAS

GO Terms for Appendiceal Neoplasm

Biological processes related to Appendiceal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of long-term neuronal synaptic plasticity GO:0048169 8.92 KRAS HRAS

Sources for Appendiceal Neoplasm

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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