MCID: APP010
MIFTS: 46

Appendix Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Appendix Cancer

MalaCards integrated aliases for Appendix Cancer:

Name: Appendix Cancer 12 15
Appendiceal Neoplasms 45 74
Malignant Neoplasm of Appendix Vermiformis 12
Malignant Tumor of the Appendix 12
Malignant Neoplasm of Appendix 74
Malignant Tumor of Appendix 12
Carcinoma of the Appendix 74
Cancer of the Appendix 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11239
ICD9CM 36 153.5
MeSH 45 D001063
NCIt 51 C9333
SNOMED-CT 69 93679002
ICD10 34 C18.1

Summaries for Appendix Cancer

Disease Ontology : 12 A intestinal cancer that is located in the appendix.

MalaCards based summary : Appendix Cancer, also known as appendiceal neoplasms, is related to appendix adenocarcinoma and pseudomyxoma peritonei. An important gene associated with Appendix Cancer is KRT7 (Keratin 7), and among its related pathways/superpathways are Circadian entrainment and fMLP Pathway. The drugs Oxaliplatin and Liver Extracts have been mentioned in the context of this disorder. Affiliated tissues include appendix, lung and colon, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 77 Appendix cancer are very rare cancers of the vermiform... more...

Related Diseases for Appendix Cancer

Diseases related to Appendix Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)
# Related Disease Score Top Affiliating Genes
1 appendix adenocarcinoma 32.1 CDX2 KRT20 KRT7
2 pseudomyxoma peritonei 30.6 CDX2 KRAS KRT20 KRT7 MUC1 MUC6
3 ovarian cystadenocarcinoma 29.8 GNAS HRAS KRAS
4 cystadenocarcinoma 29.5 HRAS KRT7 MUC1
5 adenocarcinoma 29.4 GNAS HRAS KRAS MUC1
6 cystadenoma 29.2 KRT20 KRT7 MUC1 MUC6
7 mucinous adenocarcinoma 29.0 CDX2 KRAS KRT20 KRT7 MUC1
8 colorectal cancer 27.6 CDX2 GNAS HRAS KRAS KRT20 KRT7
9 appendiceal neoplasm 12.5
10 appendix carcinoid tumor 11.2
11 anus cancer 10.4 CDX2 KRT7
12 hidradenocarcinoma 10.4 CDX2 KRT7
13 sex cord-gonadal stromal tumor 10.4 GNAS KRT7
14 pregnancy adenoma 10.4 GNAS KRT7
15 ovarian clear cell carcinoma 10.4 KRAS KRT7
16 ovary neuroendocrine neoplasm 10.3 CDX2 KRT7
17 mucinous adenofibroma 10.3 CDX2 KRT7
18 large cell neuroendocrine carcinoma 10.3 KRT20 KRT7
19 anus adenocarcinoma 10.3 CDX2 KRT7
20 immune system organ benign neoplasm 10.3 KRT20 KRT7
21 thymus lipoma 10.3 KRT20 KRT7
22 ovarian brenner tumor 10.3 KRT20 KRT7
23 inverted papilloma 10.3 KRT20 KRT7
24 ovarian cystic teratoma 10.3 KRT20 KRT7
25 appendicitis 10.3
26 cervical adenosquamous carcinoma 10.3 KRT7 MUC6
27 epithelial predominant wilms' tumor 10.3 CDX2 KRT7
28 nasal cavity cancer 10.3 CDX2 KRT7
29 cystic basal cell carcinoma 10.3 KRT20 KRT7
30 seminal vesicle adenocarcinoma 10.3 KRT20 KRT7
31 transverse colon cancer 10.3 KRT20 KRT7
32 malignant syringoma 10.3 KRT20 KRT7
33 papillary transitional carcinoma 10.3 KRT20 KRT7
34 vaginal benign neoplasm 10.3 CDX2 KRT20
35 eyelid carcinoma 10.3 KRT20 KRT7
36 urachal adenocarcinoma 10.3 GNAS KRAS
37 vaginal adenoma 10.3 CDX2 KRT20
38 krukenberg carcinoma 10.3 KRT20 KRT7
39 vaginal tubulovillous adenoma 10.3 CDX2 KRT20
40 large intestine adenocarcinoma 10.3 KRT20 KRT7
41 linitis plastica 10.3 KRT20 KRT7
42 lung acinar adenocarcinoma 10.3 KRT20 KRT7
43 small cell carcinoma of the bladder 10.3 KRT20 KRT7
44 adenoid squamous cell carcinoma 10.2 KRT20 KRT7
45 mixed cell type cancer 10.2 HRAS KRT7
46 intratubular embryonal carcinoma 10.2 KRT20 KRT7
47 epithelial-myoepithelial carcinoma 10.2 HRAS KRT7
48 mucinous intrahepatic cholangiocarcinoma 10.2 CDX2 MUC6
49 vulval paget's disease 10.2 KRT20 KRT7
50 cervical polyp 10.2 CDX2 MUC6

Comorbidity relations with Appendix Cancer via Phenotypic Disease Network (PDN):


Cecal Benign Neoplasm

Graphical network of the top 20 diseases related to Appendix Cancer:



Diseases related to Appendix Cancer

Symptoms & Phenotypes for Appendix Cancer

GenomeRNAi Phenotypes related to Appendix Cancer according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.47 HRAS KRAS MUC1
2 Decreased viability GR00106-A-0 9.47 KRAS
3 Decreased viability GR00221-A-1 9.47 HRAS KRAS
4 Decreased viability GR00221-A-2 9.47 HRAS KRAS
5 Decreased viability GR00221-A-3 9.47 HRAS
6 Decreased viability GR00301-A 9.47 KRAS
7 Decreased viability GR00381-A-1 9.47 KRAS
8 Decreased viability GR00402-S-2 9.47 HRAS KRAS MUC1

Drugs & Therapeutics for Appendix Cancer

Drugs for Appendix Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 153)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61825-94-3 43805 6857599 5310940 9887054
2 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
3 Cola Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
4
leucovorin Approved Phase 3,Phase 2,Phase 1 58-05-9 143 6006
5
Fluorouracil Approved Phase 3,Phase 2,Phase 1 51-21-8 3385
6
Paclitaxel Approved, Vet_approved Phase 3,Phase 1 33069-62-4 36314
7
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
8
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
9
Ondansetron Approved Phase 3 99614-02-5 4595
10
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
11
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
12 Pancreatic Polypeptide Investigational Phase 3,Phase 2,Phase 1 59763-91-6
13 Albumin-Bound Paclitaxel Phase 3,Phase 1
14 Narcotics Phase 3
15 Adjuvants, Anesthesia Phase 3
16 Analgesics Phase 3
17 Anesthetics, Intravenous Phase 3
18 Anesthetics, General Phase 3
19 Anesthetics Phase 3
20 Analgesics, Opioid Phase 3
21 Central Nervous System Depressants Phase 3
22 Peripheral Nervous System Agents Phase 3,Phase 2
23
protease inhibitors Phase 3
24 Tranquilizing Agents Phase 3
25 BB 1101 Phase 3
26 glucocorticoids Phase 3
27 HIV Protease Inhibitors Phase 3
28 Hormone Antagonists Phase 3
29 Serotonin Agents Phase 3,Phase 2
30 Hormones Phase 3
31 Antineoplastic Agents, Hormonal Phase 3
32 Dermatologic Agents Phase 3,Not Applicable
33 Serotonin Antagonists Phase 3,Phase 2
34 Psychotropic Drugs Phase 3
35 Anti-Inflammatory Agents Phase 3
36 Neurotransmitter Agents Phase 3,Phase 2
37 Anti-Anxiety Agents Phase 3
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
39 Antiemetics Phase 3,Phase 2
40 Antipruritics Phase 3
41 Antipsychotic Agents Phase 3
42 Gastrointestinal Agents Phase 3,Phase 2
43 Autonomic Agents Phase 3,Phase 2
44
Serotonin Investigational, Nutraceutical Phase 3,Phase 2 50-67-9 5202
45
Levoleucovorin Approved, Investigational Phase 2,Phase 1 68538-85-2
46
Doxorubicin Approved, Investigational Phase 2,Not Applicable 23214-92-8 31703
47
Pancrelipase Approved, Investigational Phase 2 53608-75-6
48
Melphalan Approved Phase 2 148-82-3 460612 4053
49
Floxuridine Approved Phase 2,Phase 1 50-91-9 5790
50
Irinotecan Approved, Investigational Phase 2,Phase 1 100286-90-6, 97682-44-5 60838

Interventional clinical trials:

(show top 50) (show all 51)
# Name Status NCT ID Phase Drugs
1 Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal Cancer Unknown status NCT00274885 Phase 4 oxaliplatin
2 Debulking and Chemotherapy With or Without Intraperitoneal Chemotherapy to Treat Peritoneal Carcinomatosis Completed NCT00052962 Phase 3
3 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
4 Ondansetron With or Without Dexamethasone to Prevent Vomiting in Patients Receiving Radiation Therapy to the Upper Abdomen Completed NCT00016380 Phase 3 dexamethasone;ondansetron
5 Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer Unknown status NCT00006112 Phase 2 chemotherapy;fluorouracil;leucovorin calcium;mitomycin C
6 Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer Completed NCT00310076 Phase 2 thalidomide
7 Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix Completed NCT01580410 Phase 2 mitomycin C;oxaliplatin;hyperthermic intraperitoneal chemotherapy
8 Treating Peritoneal Carcinomatosis With PIPAC Completed NCT02320448 Phase 2 PIPAC
9 Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer Completed NCT00096083 Phase 2 isolated perfusion;melphalan
10 LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma Recruiting NCT03287947 Phase 2 nintedanib
11 ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis Recruiting NCT01815359 Phase 2 HIPEC with Mitomycin-C;EPIC with FUDR and Leucovorin
12 A Phase 1/2 Study to Investigate the Safety, Biologic and Anti-tumor Activity of ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies Recruiting NCT02963831 Phase 1, Phase 2 Durvalumab
13 Treatment of Peritoneal Carcinomatosis With Pressurized IntraPeritoneal Aerosol Chemotherapy - Recruiting NCT03287375 Phase 2 PIPAC
14 Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin Recruiting NCT02387203 Phase 2 PrevPac (Prevacid, Amoxicillin, Clarithromycin)
15 Nivolumab and Ipilimumab in Mucinous Colorectal and Appendiceal Tumors Recruiting NCT03693846 Phase 2 Nivolumab;Ipilimumab
16 PIPAC for Peritoneal Metastases of Colorectal Cancer Recruiting NCT03246321 Phase 2
17 Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis Recruiting NCT03073694 Phase 2 Mitomycin c;Melphalan
18 Single Arm Study Treating Patients of Peritoneal Surface Malignancy (Colorectal, Appendical, Pseudomyxoma, Gastric) With Cytoreductive Surgery and Hyperthermic Intraperitoneal Mitomycin-C Enrolling by invitation NCT02040142 Phase 2 Mitomycin C
19 Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer Terminated NCT00903396 Phase 2 palonosetron hydrochloride
20 Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia Terminated NCT00180960 Phase 2 Oxaliplatin and irinotecan
21 Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer Completed NCT00458809 Phase 1 oxaliplatin
22 Oxaliplatin Plus Capecitabine in Treating Patients With Colorectal, Appendix, or Small Bowel Cancer Completed NCT00019773 Phase 1 capecitabine;oxaliplatin
23 Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer Completed NCT00654160 Phase 1 fluorouracil;irinotecan hydrochloride;leucovorin calcium
24 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) Completed NCT00031681 Phase 1 7-hydroxystaurosporine;irinotecan hydrochloride
25 Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer Completed NCT00397384 Phase 1 cetuximab;erlotinib hydrochloride
26 Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu Completed NCT00004074 Phase 1
27 Interleukin-12 in Treating Patients With Cancer in the Abdomen Completed NCT00003046 Phase 1
28 Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer Completed NCT00005842 Phase 1 tipifarnib
29 Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum Completed NCT00005860 Phase 1 floxuridine;leucovorin calcium;oxaliplatin
30 Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity Completed NCT00003548 Phase 1 aminocamptothecin colloidal dispersion
31 Irinotecan and Capecitabine in Treating Patients With Solid Tumors Completed NCT00003867 Phase 1 capecitabine;irinotecan hydrochloride
32 PV701 in Treating Patients With Advanced or Recurrent Peritoneal Cancer Completed NCT00055705 Phase 1
33 Thalidomide and Docetaxel in Treating Patients With Advanced Cancer Completed NCT00049296 Phase 1 docetaxel;thalidomide
34 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
35 Capecitabine Combined With Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors Completed NCT00010023 Phase 1 capecitabine;cisplatin
36 Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI Recruiting NCT02833753 Phase 1 Oxaliplatin
37 Safety and Effect of GL-ONC1 Administered IV Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery Active, not recruiting NCT02714374 Phase 1
38 Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Completed NCT01126346 Not Applicable
39 Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients Completed NCT00253383 Not Applicable
40 Low vs. Standard Dose CT for Appendicitis Trial Completed NCT01925014 Not Applicable
41 Knowledge, Attitudes, and Practice of Surgeons Toward Nutrition Support in HIPEC Patients Completed NCT02374411
42 Gastrointestinal Microbiome Study of Appendiceal Cancer Recruiting NCT02599116 Not Applicable
43 Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei Recruiting NCT01946854 Not Applicable
44 Radical Resection and HIPEC for Recurrent Retroperitoneal Sarcoma Recruiting NCT03792867 Not Applicable Doxorubicin
45 Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers Recruiting NCT03604653 Mitomycin c;CDDP;CDDP;Doxorubicin
46 International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) Recruiting NCT03210298
47 The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial Recruiting NCT02800785 Not Applicable Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin
48 Selective Rather Than Routine Histopathological Examination After Appendectomy and Cholecystectomy Recruiting NCT03510923
49 Postoperative Chemotherapy in High-Grade Appendiceal Adenocarcinoma With Peritoneal Carcinomatosis Active, not recruiting NCT02420509 systemic chemotherapy
50 Distant Metastases and Long-Term Survival After Complete Resection of Neuroendocrine Tumors of the Appendix Not yet recruiting NCT03852693

Search NIH Clinical Center for Appendix Cancer

Cochrane evidence based reviews: appendiceal neoplasms

Genetic Tests for Appendix Cancer

Anatomical Context for Appendix Cancer

MalaCards organs/tissues related to Appendix Cancer:

42
Appendix, Lung, Colon, Liver, Breast, Ovary, Pancreas

The Foundational Model of Anatomy Ontology organs/tissues related to Appendix Cancer:

20
The Appendix

Publications for Appendix Cancer

Articles related to Appendix Cancer:

(show all 46)
# Title Authors Year
1
Mucinous appendiceal neoplasms: classification, imaging, and HIPEC. ( 30610247 )
2019
2
Spectrum of computed tomography manifestations of appendiceal neoplasms: acute appendicitis and beyond. ( 31069398 )
2019
3
Review: Pathology and Its Clinical Relevance of Mucinous Appendiceal Neoplasms and Pseudomyxoma Peritonei. ( 30611664 )
2018
4
Appendiceal Neoplasms. ( 30186049 )
2018
5
Single-center analysis of appendiceal neoplasms. ( 29731850 )
2018
6
Mucinous appendiceal neoplasms: pathologic classification, clinical implications, imaging spectrum and mimics. ( 29564494 )
2018
7
Correction to: Tan et al., Diagnostic and therapeutic laparoscopy in assessment and management of patients with appendiceal neoplasms. ( 28967270 )
2018
8
Diagnostic and therapeutic laparoscopy in assessment and management of patients with appendiceal neoplasms. ( 28605985 )
2018
9
Analysis of Appendiceal Neoplasms on 3544 Appendectomy Specimens for Acute Appendicitis: Retrospective Cohort Study of a Single Institution. ( 29947345 )
2018
10
The histopathological classification, diagnosis and differential diagnosis of mucinous appendiceal neoplasms, appendiceal adenocarcinomas and pseudomyxoma peritonei. ( 28746986 )
2017
11
Expert Commentary on Appendiceal Neoplasms. ( 29112558 )
2017
12
Appendiceal Neoplasms. ( 29112557 )
2017
13
Two concurrent appendiceal neoplasms in an elderly patient: A case report. ( 28988021 )
2017
14
Mucinous appendiceal neoplasms: Incidence, diagnosis and surgical treatment. ( 28655402 )
2017
15
Radical appendectomy as an alternative to right colon resection in patients with epithelial appendiceal neoplasms. ( 28317590 )
2017
16
When and When Not to Perform a Right Colon Resection with Mucinous Appendiceal Neoplasms. ( 27770344 )
2017
17
Occult Appendiceal Neoplasms in Acute and Chronic Appendicitis: A Single-Institution Experience of 1793 Appendectomies. ( 29336758 )
2017
18
Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care. ( 28591173 )
2017
19
Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion in Patients with High-Grade, High-Volume Disseminated Mucinous Appendiceal Neoplasms. ( 26429720 )
2016
20
Preoperative CT and MRI prediction of non-resectability in patients treated for pseudomyxoma peritonei from mucinous appendiceal neoplasms. ( 26856956 )
2016
21
Recommendations in the management of epithelial appendiceal neoplasms and peritoneal dissemination from mucinous tumours (pseudomyxoma peritonei). ( 26489426 )
2016
22
Prophylactic hyperthermic intraperitoneal chemotherapy in patients with epithelial appendiceal neoplasms. ( 27050712 )
2016
23
Guidelines on the use of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal surface malignancy arising from colorectal or appendiceal neoplasms. ( 25908915 )
2015
24
Management of Appendix Cancer. ( 26648795 )
2015
25
Does obesity affect outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemoperfusion for disseminated mucinous appendiceal neoplasms? ( 24916747 )
2014
26
Evaluation of a new staging classification and a Peritoneal Surface Disease Severity Score (PSDSS) in 229 patients with mucinous appendiceal neoplasms with or without peritoneal dissemination. ( 24898451 )
2014
27
Mucinous appendiceal neoplasms. Do we all speak the same language? ( 22300121 )
2012
28
Inflammatory markers in blood and serum tumor markers predict survival in patients with epithelial appendiceal neoplasms undergoing surgical cytoreduction and intraperitoneal chemotherapy. ( 22750758 )
2012
29
Aggressive management of peritoneal carcinomatosis from mucinous appendiceal neoplasms. ( 22302270 )
2012
30
Systemic Chemotherapy prior to Cytoreductive Surgery and HIPEC for Carcinomatosis from Appendix Cancer: Impact on Perioperative Outcomes and Short-Term Survival. ( 22899903 )
2012
31
Is malignant dedifferentiation for mucinous appendiceal neoplasms a valid phenomenon or merely histopathologic ambiguity? ( 21530846 )
2011
32
Significant association of appendiceal neoplasms and ulcerative colitis rather than Crohn's disease. ( 19705419 )
2010
33
Clinicopathological analysis of primary epithelial appendiceal neoplasms. ( 19851895 )
2010
34
Epithelial appendiceal neoplasms. ( 19556909 )
2009
35
Appendiceal mucinous cystadenoma is a neoplastic complication of IBD: case-control study of primary appendiceal neoplasms. ( 18989894 )
2009
36
The porta hepatis as a site of recurrence of mucinous appendiceal neoplasms treated by cytoreductive surgery and perioperative intraperitoneal chemotherapy. ( 19112943 )
2008
37
Mucinous appendiceal neoplasms: preoperative MR staging and classification compared with surgical and histopathologic findings. ( 18287436 )
2008
38
Appendiceal neoplasms and pseudomyxoma peritonei: a population based study. ( 17524597 )
2008
39
Appendiceal neoplasms with peritoneal dissemination: outcomes after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy. ( 16538401 )
2006
40
The "alphabet soup" of peritoneal dissemination from appendiceal neoplasms and other malignancies. ( 16538404 )
2006
41
Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms. ( 15807473 )
2004
42
Synchronous extraperitoneal and intraperitoneal dissemination of appendix cancer. ( 15336733 )
2004
43
Appendix cancer mimicking ovarian cancer. ( 12445258 )
2002
44
Surgical debulking and intraperitoneal chemotherapy for established peritoneal metastases from colon and appendix cancer. ( 11776492 )
2001
45
Primary appendiceal neoplasms. ( 8270409 )
1993
46
Mucinous adenocarcinoma of the appendix presenting as an ovarian cystadenocarcinoma: case report and review of appendiceal neoplasms with ovarian metastases. ( 3023143 )
1986

Variations for Appendix Cancer

Expression for Appendix Cancer

Search GEO for disease gene expression data for Appendix Cancer.

Pathways for Appendix Cancer

Pathways related to Appendix Cancer according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 GNAS HRAS KRAS KRT20
2
Show member pathways
12.73 CDX2 GNAS HRAS KRAS
3
Show member pathways
12.13 GNAS HRAS KRAS
4
Show member pathways
11.83 GNAS HRAS KRAS
5
Show member pathways
11.72 GNAS HRAS KRAS
6
Show member pathways
11.67 HRAS KRAS MUC1 MUC6
7 11.49 GNAS HRAS KRAS
8 11.28 GNAS HRAS KRAS
9 11.22 HRAS KRAS
10 11.14 GNAS HRAS KRAS
11 11.08 HRAS KRAS
12 11.01 HRAS KRAS
13 11 HRAS KRAS
14
Show member pathways
10.97 HRAS KRAS
15
Show member pathways
10.91 HRAS KRAS
16 10.84 HRAS KRAS
17 10.8 HRAS KRAS
18 10.71 HRAS KRAS
19 10.58 GNAS HRAS KRAS
20 10.44 HRAS KRAS

GO Terms for Appendix Cancer

Biological processes related to Appendix Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of long-term neuronal synaptic plasticity GO:0048169 9.16 HRAS KRAS
2 response to isolation stress GO:0035900 8.96 HRAS KRAS
3 stimulatory C-type lectin receptor signaling pathway GO:0002223 8.92 HRAS KRAS MUC1 MUC6

Molecular functions related to Appendix Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 methyl-CpG binding GO:0008327 8.62 CDX2 ZBTB38

Sources for Appendix Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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