MCID: APP002
MIFTS: 23

Appendix Lymphoma

Categories: Blood diseases, Cancer diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Appendix Lymphoma

MalaCards integrated aliases for Appendix Lymphoma:

Name: Appendix Lymphoma 12 15 70
Appendiceal Lymphoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11241
NCIt 50 C5513
UMLS 70 C1332328

Summaries for Appendix Lymphoma

MalaCards based summary : Appendix Lymphoma, also known as appendiceal lymphoma, is related to gastrointestinal lymphoma and b-cell lymphoma. An important gene associated with Appendix Lymphoma is BCL6 (BCL6 Transcription Repressor). Affiliated tissues include appendix, thyroid and breast, and related phenotype is no phenotypic analysis.

Related Diseases for Appendix Lymphoma

Diseases related to Appendix Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 gastrointestinal lymphoma 29.8 MME CD5 BCL6
2 b-cell lymphoma 29.8 MYC MME CD5 BCL6
3 diffuse large b-cell lymphoma 29.7 MYC MME CD5 BCL6
4 follicular lymphoma 29.5 MYC MME CD5 BCL6
5 lymphoma, non-hodgkin, familial 29.4 MYC MME CD5 BCL6
6 heart lymphoma 10.3 MME BCL6
7 ovarian lymphoma 10.3 MME BCL6
8 high grade b-cell lymphoma with myc and/ or bcl2 and/or bcl6 rearrangement 10.3 MYC BCL6
9 lymphoma aids related 10.3 MYC BCL6
10 t-cell/histiocyte rich large b cell lymphoma 10.3 MME BCL6
11 gray zone lymphoma 10.3 MME BCL6
12 plasmablastic lymphoma 10.3 MYC BCL6
13 testicular lymphoma 10.3 MME BCL6
14 pancreatic serous cystadenocarcinoma 10.2 MME CHGA
15 female urethral cancer 10.2 MME CHGA
16 aids phobia 10.2 TAC1 MME
17 autoimmune atrophic gastritis 10.2 GAST CHGA
18 mixed ductal-endocrine carcinoma 10.2 GAST CHGA
19 intrahepatic bile duct adenoma 10.2 MME CHGA
20 appendicitis 10.2
21 cerebral lymphoma 10.2 SST MME
22 paranasal sinus lymphoma 10.2 MYC MME BCL6
23 pediatric lymphoma 10.1 MYC MME BCL6
24 thyrotoxic exophthalmos 10.1 MME CD5
25 endocrine exophthalmos 10.1 MME CD5
26 rectum neuroendocrine neoplasm 10.1 SST GAST
27 neurogenic bowel 10.1 TAC1 GAST
28 eye lymphoma 10.1 CD5 BCL6
29 postgastrectomy syndrome 10.1 SST GAST
30 duodenal somatostatinoma 10.1 SST GAST
31 akinetopsia 10.1 TAC1 KLK4
32 duodenal benign neoplasm 10.1 SST CHGA
33 gastric antral vascular ectasia 10.1 SST GAST
34 b cell prolymphocytic leukemia 10.1 MYC CD5
35 facial dermatosis 10.1 TAC1 KLK4
36 laryngeal neuroendocrine tumor 10.1 SST CHGA
37 ectopic cushing syndrome 10.1 SST CHGA
38 binswanger's disease 10.1 SST CHGA
39 duodenogastric reflux 10.1 SST GAST
40 meckel diverticulum 10.1 SST CHGA
41 duodenum cancer 10.1 SST GAST
42 papillary thymic adenocarcinoma 10.1 CHGA CD5
43 duodenum disease 10.1 SST GAST
44 adrenal medulla cancer 10.1 SST CHGA
45 dumping syndrome 10.1 SST GAST
46 respiratory system benign neoplasm 10.1 MYC CHGA
47 aggressive nk-cell leukemia 10.1 MYC CD5
48 reticulosarcoma 10.0 MYC BCL6
49 transient refractive change 10.0 TAC1 SST
50 pancreatoblastoma 10.0 SST CHGA

Graphical network of the top 20 diseases related to Appendix Lymphoma:



Diseases related to Appendix Lymphoma

Symptoms & Phenotypes for Appendix Lymphoma

MGI Mouse Phenotypes related to Appendix Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.02 BCL6 CD5 CHGA MYC SST

Drugs & Therapeutics for Appendix Lymphoma

Search Clinical Trials , NIH Clinical Center for Appendix Lymphoma

Genetic Tests for Appendix Lymphoma

Anatomical Context for Appendix Lymphoma

MalaCards organs/tissues related to Appendix Lymphoma:

40
Appendix, Thyroid, Breast, Lung, Bone, Colon, Prostate

Publications for Appendix Lymphoma

Articles related to Appendix Lymphoma:

(show all 15)
# Title Authors PMID Year
1
Burkitt Leukemia Presenting as Acute Appendicitis: A Case Report and Literature Review. 61
32094318 2020
2
Primary lymphoma of appendix presenting as acute appendicitis: A case report. 61
29778032 2018
3
Primary appendiceal lymphoma: clinical characteristics and outcomes of 116 patients. 61
27979474 2017
4
Primary appendiceal lymphoma presenting as suspected perforated acute appendicitis: clinical, sonography and CT findings with pathologic correlation. 61
25400798 2014
5
Primary appendiceal lymphoma presenting as acute appendicitis. 61
21679577 2011
6
Unusual presentation for primary appendiceal lymphoma: A case report. 61
23133274 2010
7
Value of routine histopathologic examination of three common surgical specimens: appendix, gallbladder, and hemorrhoid. 61
19669232 2009
8
Nonendemic Burkitt lymphoma presenting with an atypical clinical picture. 61
17805048 2007
9
Primary appendiceal lymphoma presenting as perforated acute appendicitis. 61
15779487 2004
10
Non-Hodgkin's lymphoma of the appendix: clinical and CT findings with pathologic correlation. 61
11959713 2002
11
Involvement of the appendix in a relapsed case of primary nasal NK/T-cell lymphoma. 61
11042526 2000
12
Endoscopic appearance of primary appendiceal lymphoma. 61
9684675 1998
13
Primary lymphoma of the appendix. Case report and review of the literature. 61
7834115 1994
14
Appendiceal lymphoma: a case report. 61
1744403 1991
15
Lymphoma of the appendix. 61
1879646 1991

Variations for Appendix Lymphoma

Expression for Appendix Lymphoma

Search GEO for disease gene expression data for Appendix Lymphoma.

Pathways for Appendix Lymphoma

GO Terms for Appendix Lymphoma

Cellular components related to Appendix Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 8.92 TAC1 SST MME ENO2

Sources for Appendix Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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