MCID: ARG004
MIFTS: 26

Argyria

Categories: Rare diseases

Aliases & Classifications for Argyria

MalaCards integrated aliases for Argyria:

Name: Argyria 58
Silver Staining 58

Characteristics:

Orphanet epidemiological data:

58
argyria
Inheritance: Not applicable; Age of onset: Adult; Age of death: normal life expectancy;

Classifications:



External Ids:

MESH via Orphanet 45 D001129
ICD10 via Orphanet 33 T56.8
UMLS via Orphanet 71 C0003782
Orphanet 58 ORPHA60014

Summaries for Argyria

MalaCards based summary : Argyria, also known as silver staining, is related to dowling-degos disease 1 and ochronosis. The drugs Guaifenesin and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include endothelial, cortex and pituitary.

Wikipedia : 73 Argyria or argyrosis is a condition caused by excessive exposure to chemical compounds of the element... more...

Related Diseases for Argyria

Diseases related to Argyria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 185)
# Related Disease Score Top Affiliating Genes
1 dowling-degos disease 1 10.2
2 ochronosis 10.2
3 cyanosis, transient neonatal 10.2
4 tièche-jadassohn nevus 10.1
5 triiodothyronine receptor auxiliary protein 10.1
6 clonorchiasis 10.1
7 adenocarcinoma 10.1
8 skin disease 10.0
9 huntington disease 10.0
10 multiple system atrophy 1 10.0
11 sarcoidosis 1 10.0
12 suppressor of tumorigenicity 3 10.0
13 senile plaque formation 10.0
14 leukemia, acute lymphoblastic 10.0
15 oral squamous cell carcinoma 10.0
16 acute leukemia 10.0
17 lymphadenitis 10.0
18 viral hepatitis 10.0
19 lysosomal storage disease 10.0
20 adenosquamous carcinoma 10.0
21 peripheral nervous system disease 10.0
22 acquired immunodeficiency syndrome 10.0
23 measles 10.0
24 in situ carcinoma 10.0
25 wallerian degeneration 10.0
26 posttransplant acute limbic encephalitis 10.0
27 thyroid carcinoma 10.0
28 hemochromatosis, type 1 10.0
29 wilson disease 10.0
30 melanoma 10.0
31 epidermolysis bullosa 10.0
32 epidermolysis bullosa dystrophica 10.0
33 stevens-johnson syndrome/toxic epidermal necrolysis 10.0
34 pfeiffer syndrome 9.8
35 alzheimer disease 9.8
36 bladder cancer 9.8
37 cat eye syndrome 9.8
38 factor viii deficiency 9.8
39 congenital anomalies of kidney and urinary tract 2 9.8
40 hypercholesterolemia, familial, 1 9.8
41 renal cell carcinoma, nonpapillary 9.8
42 hypertriglyceridemia, familial 9.8
43 kaposi sarcoma 9.8
44 lentigines 9.8
45 leukemia, chronic lymphocytic 9.8
46 thyroid carcinoma, familial medullary 9.8
47 mesothelioma, malignant 9.8
48 schistosoma mansoni infection, susceptibility/ 9.8
49 buerger disease 9.8
50 macular dystrophy, corneal 9.8

Symptoms & Phenotypes for Argyria

Drugs & Therapeutics for Argyria

Drugs for Argyria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
2
Metronidazole Approved Phase 4 443-48-1 4173
3
Clarithromycin Approved Phase 4 81103-11-9 84029
4
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
5
Phenylpropanolamine Approved, Vet_approved, Withdrawn Phase 4 14838-15-4 26934
6
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
7 Chlorpheniramine, phenylpropanolamine drug combination Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Eradication of Helicobacter Pylori According to 23S rRNA Point Mutations Associated With Clarithromycin Resistance Completed NCT01453036 Phase 4

Search NIH Clinical Center for Argyria

Genetic Tests for Argyria

Anatomical Context for Argyria

MalaCards organs/tissues related to Argyria:

40
Endothelial, Cortex, Pituitary, Bone Marrow, Spinal Cord, Prostate, Brain

Publications for Argyria

Articles related to Argyria:

(show top 50) (show all 5785)
# Title Authors PMID Year
1
Quartz crystal microbalance cardiac Troponin I immunosensors employing signal amplification with TiO2 nanoparticle photocatalyst. 61
33773737 2021
2
A visual bio-barcode immunoassay for sensitive detection of triazophos based on biochip silver staining signal amplification. 61
33461115 2021
3
Electroacupuncture improves neuronal plasticity through the A2AR/cAMP/PKA signaling pathway in SNL rats. 61
33577869 2021
4
Incorporating mitogenome sequencing into integrative taxonomy: The multidisciplinary redescription of the ciliate Thuricola similis (Peritrichia, Vaginicolidae) provides new insights into the evolutionary relationships among Oligohymenophorea subclasses. 61
33545277 2021
5
Oral leukoplakia-epidemiological survey and histochemical analysis of 107 cases in Brazil. 61
32761445 2021
6
[Effect of electroacupuncture on angiopoietin-1 in spinal cord of rats with neuropathic pain]. 61
33798293 2021
7
Morphological speculation of the MHPD and related clinical projections. 61
33661355 2021
8
Oxidized low-density lipoprotein activates extracellular signal-regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells. 61
33694195 2021
9
Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice. 61
33646289 2021
10
Characteristics of Brucella abortus vaccine strain A19 reveals its potential mechanism of attenuated virulence. 61
33582483 2021
11
Loss of the virulence plasmid by Shigella sonnei promotes its interactions with CD207 and CD209 receptors. 61
33591245 2021
12
The lipopolysaccharide outer core transferase genes pcgD and hptE contribute differently to the virulence of Pasteurella multocida in ducks. 61
33663572 2021
13
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma. 61
33692132 2021
14
The role of silver coating for arthroplasty components. 61
33641432 2021
15
A terminal alkyne and disulfide functionalized agarose resin specifically enriches azidohomoalanine labeled nascent proteins. 61
33486215 2021
16
Detection of Glycosaminoglycans by Polyacrylamide Gel Electrophoresis and Silver Staining. 61
33720131 2021
17
Occupational Localized Cutaneous Argyria With Pseudo-Ochronosis in a Jeweler. 61
33606379 2021
18
Silver-coated megaprosthesis in prevention and treatment of peri-prosthetic infections: a systematic review and meta-analysis about efficacy and toxicity in primary and revision surgery. 61
32889672 2021
19
Hippocampal-Dependent Cognitive Dysfunction Following Repeated Diffuse Rotational Brain Injury in Male and Female Mice. 61
33622092 2021
20
A colorimetric immuno-microarray for the quantitation and direct visualization of illicit drugs in body fluids. 61
33165458 2021
21
Inhibition of persimmon tannin extract on guinea pig skin pigmentation. 61
33480158 2021
22
Inter-Simple Sequence Repeats (ISSR), Microsatellite-Primed Genomic Profiling Using Universal Primers. 61
33301098 2021
23
Rapid and sensitive electrochemical detection of microRNAs by gold nanoparticle-catalyzed silver enhancement. 61
33016298 2021
24
Drug Affinity Responsive Target Stability (DARTS ) Assay to Detect Interaction Between a Purified Protein and a Small Molecule. 61
33270202 2021
25
Exploitation of Capsule Polymerases for Enzymatic Synthesis of Polysaccharide Antigens Used in Glycoconjugate Vaccines. 61
32959251 2021
26
Increased mRNA expression of key cytokines among suspected cases of Pneumocystis jirovecii infection. 61
33413198 2021
27
Sidestream Smoke Affects Dendritic Complexity and Astrocytes After Model Mild Closed Head Traumatic Brain Injury. 61
33417143 2021
28
Detection of RNA viruses from influenza and HIV to Ebola and SARS-CoV-2: a review. 61
33283798 2021
29
Silver in biology and medicine: opportunities for metallomics researchers. 61
33570135 2021
30
Argyria: a cause of pseudocyanosis. 61
33401304 2021
31
Toxicity of colloidal silver products and their marketing claims in Finland. 61
33437653 2021
32
Argentic staining reveals changes in cerebellar tissue organisation by prenatal glucocorticoid administration in rats. 61
33331648 2020
33
Postnatal Growth Restriction in Mice Alters Cardiac Protein Composition and Leads to Functional Impairment in Adulthood. 61
33322681 2020
34
Danio rerio as an alternative vertebrate model for jellyfish venom study: The toxinological aspects of Nemopilema nomurai venom. 61
33157172 2020
35
A digital image analysis study on the disintegration kinetics of reticular fibers in the ethylene glycol-induced rat liver tissue. 61
33220018 2020
36
[A school-aged boy with nephrotic syndrome with cough for one month and shortness of breath for half a month]. 61
33328005 2020
37
Inhibition of Aβ aggregates in Alzheimer's disease by epigallocatechin and epicatechin-3-gallate from green tea. 61
33137558 2020
38
Elevated level of uric acid in aqueous humour is associated with posterior subcapsular cataract in human lens. 61
32713071 2020
39
Generalized Argyria Successfully Treated with Q-switched Alexandrite Laser: A Case Report. 61
33283247 2020
40
A clinical mimicker of melanoma with distinctive histopathology: Topical silver nitrate exposure. 61
32803880 2020
41
Methamphetamine leads to the alterations of microRNA profiles in the nucleus accumbens of rats. 61
32893733 2020
42
D-serine Ameliorates Motor and Cognitive Impairments in β-amyloid 1-42 Injected Mice by Inhibiting JNK Signaling Pathway. 61
32781134 2020
43
Occurrence of primary progressive multiple sclerosis in a patient with argyria: Causality or coincidence? 61
32890815 2020
44
Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging. 61
32726643 2020
45
[Observation of dendrite osteocytes of mice at different developmental stages using Ploton silver staining and phalloidin staining]. 61
33243734 2020
46
Ribosomal DNA transcription in prefrontal pyramidal neurons is decreased in suicide. 61
30859295 2020
47
Adenosine A2A Receptors in Bone Marrow-Derived Cells Attenuate Cognitive Impairment in Mice After Chronic Hypoperfusion White Matter Injury. 61
32394183 2020
48
Genetic characterization and assessment of diversity in Pandharpuri buffalo breed of India using heterologous microsatellite markers. 61
31092100 2020
49
High Sensitivity Protein Gel Electrophoresis Label Compatible with Mass-Spectrometry. 61
33142797 2020
50
Successful treatment of acupuncture-induced argyria using Q-switched 1064-nm Nd:YAG laser. 61
32995425 2020

Variations for Argyria

Expression for Argyria

Search GEO for disease gene expression data for Argyria.

Pathways for Argyria

GO Terms for Argyria

Sources for Argyria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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