MCID: ARG004
MIFTS: 28

Argyria

Categories: Rare diseases

Aliases & Classifications for Argyria

MalaCards integrated aliases for Argyria:

Name: Argyria 58
Silver Staining 58

Characteristics:

Orphanet epidemiological data:

58
argyria
Inheritance: Not applicable; Age of onset: Adult; Age of death: normal life expectancy;

Classifications:



External Ids:

MESH via Orphanet 44 D001129
ICD10 via Orphanet 33 T56.8
UMLS via Orphanet 72 C0003782
Orphanet 58 ORPHA60014

Summaries for Argyria

MalaCards based summary : Argyria, also known as silver staining, is related to pick disease of brain and dowling-degos disease 1. The drugs Guaifenesin and Clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include brain, skin and liver.

Wikipedia : 74 Argyria or argyrosis is a condition caused by excessive exposure to chemical compounds of the element... more...

Related Diseases for Argyria

Diseases related to Argyria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 267)
# Related Disease Score Top Affiliating Genes
1 pick disease of brain 11.4
2 dowling-degos disease 1 10.4
3 cyanosis, transient neonatal 10.3
4 ochronosis 10.3
5 tièche-jadassohn nevus 10.3
6 adenocarcinoma 10.2
7 lymphocytic leukemia 10.2
8 skin disease 10.2
9 hemochromatosis, type 1 10.1
10 wilson disease 10.1
11 heart disease 10.1
12 epidermolysis bullosa 10.1
13 epidermolysis bullosa dystrophica 10.1
14 stevens-johnson syndrome/toxic epidermal necrolysis 10.1
15 adenoma 10.1
16 breast cancer 10.1
17 oral squamous cell carcinoma 10.1
18 benign mesothelioma 10.1
19 acquired immunodeficiency syndrome 10.1
20 in situ carcinoma 10.1
21 posttransplant acute limbic encephalitis 10.1
22 multiple system atrophy 1 10.0
23 leukemia, chronic lymphocytic 10.0
24 mesothelioma, malignant 10.0
25 triiodothyronine receptor auxiliary protein 10.0
26 leukemia, acute lymphoblastic 10.0
27 ductal carcinoma in situ 10.0
28 lyme disease 10.0
29 acute leukemia 10.0
30 clonorchiasis 10.0
31 endometrial adenocarcinoma 10.0
32 adenosquamous carcinoma 10.0
33 rapidly involuting congenital hemangioma 10.0
34 hashimoto thyroiditis 10.0
35 porphyria cutanea tarda 10.0
36 varicose veins 10.0
37 alkaptonuria 10.0
38 osteogenic sarcoma 10.0
39 membranous nephropathy 10.0
40 hypertrophic scars 10.0
41 erythema multiforme 10.0
42 lymphoma 10.0
43 inguinal hernia 10.0
44 pyelonephritis 10.0
45 visual epilepsy 10.0
46 nephrotic syndrome 10.0
47 allergic hypersensitivity disease 10.0
48 neutropenia 10.0
49 bronchopneumonia 10.0
50 crescentic glomerulonephritis 10.0

Symptoms & Phenotypes for Argyria

Drugs & Therapeutics for Argyria

Drugs for Argyria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
2
Clarithromycin Approved Phase 4 81103-11-9 84029
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
5
Metronidazole Approved Phase 4 443-48-1 4173
6 Anti-Infective Agents Phase 4
7 Cytochrome P-450 CYP3A Inhibitors Phase 4
8 Cytochrome P-450 Enzyme Inhibitors Phase 4
9 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
10 Anti-Bacterial Agents Phase 4
11 Protective Agents
12 Fluorides
13 Cariostatic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Eradication of Helicobacter Pylori According to 23S rRNA Point Mutations Associated With Clarithromycin Resistance Completed NCT01453036 Phase 4
2 Phase 2 Study Examining the Effects of Topical Intranasal Silver Colloid in Patients With Recalcitrant Chronic Rhinosinusitis Completed NCT02403479 Phase 1, Phase 2 Silver Colloid
3 Comparison of Morphometric Assessment Using Methyl Green Pyronin and AgNOR Staining of Oral Squamous Cell Carcinoma Unknown status NCT01987934
4 Effects of DIammine SIlver Fluoride Placed Over Cervical Lesions of Permanent Teeth to Reduce Tooth Sensitivity Unknown status NCT01063530

Search NIH Clinical Center for Argyria

Genetic Tests for Argyria

Anatomical Context for Argyria

MalaCards organs/tissues related to Argyria:

40
Brain, Skin, Liver, Breast, Lung, Endothelial, Bone

Publications for Argyria

Articles related to Argyria:

(show top 50) (show all 5672)
# Title Authors PMID Year
1
Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury. 61
31638090 2020
2
Characterizations and application of CA/ZnO/AgNP composite nanofibers for sustained antibacterial properties. 61
31546450 2019
3
Analysis of chromophores in stained-glass windows using Visible Hyperspectral Imaging in-situ. 61
31323494 2019
4
Development of a rapid and improved two-dimensional electrophoresis method for the separation of protein lysate. 61
31452214 2019
5
Utility and Practicality of Multi-level Sectioning and Upfront Unstained Slide Cutting in Head and Neck Biopsies: A Critical Analysis. 61
30758755 2019
6
Dermoscopy of localised argyria: Apropos of five cases. 61
31736055 2019
7
Diffusion tensor imaging predicting neurological repair of spinal cord injury with transplanting collagen/chitosan scaffold binding bFGF. 61
31686219 2019
8
The complete life cycle of the unusual apostome Hyalophysa clampi (Ciliophora, Apostomatida), a symbiont of crayfish in Alabama (USA). 61
31805440 2019
9
Cytogenetic markers reveal a reinforcement of variation in the tension zone between chromosome races in the brachypterous grasshopper Podisma sapporensis Shir. on Hokkaido Island. 61
31728044 2019
10
Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. 61
31442443 2019
11
Cytogenetics of Eudiplozoon nipponicum (Monogenea, Diplozoidae): Karyotype, spermatocyte division and 18S rDNA location. 61
31770588 2019
12
Diazepam enhances melanogenesis, melanocyte dendricity and melanosome transport via the PBR/cAMP/PKA pathway. 61
31561018 2019
13
Effects of full-length human amelogenin on the differentiation of dental epithelial cells and osteoblastic cells. 61
31330473 2019
14
Bovine digital dermatitis in Victoria, Australia. 61
31286478 2019
15
The reniform body: An integrative lateral protocerebral neuropil complex of Eumalacostraca identified in Stomatopoda and Brachyura. 61
31621907 2019
16
Group B Rotavirus Infections in Mymensingh, 2015. 61
31599242 2019
17
Electron Microscopy of Argyria Treated With Picosecond Alexandrite Laser. 61
31517655 2019
18
Localized argyria from silver nasal piercing unresponsive to Q-switched laser successfully treated with a 1064 picoseconds laser. 61
31532572 2019
19
Biological surface properties in extracellular vesicles and their effect on cargo proteins. 61
31506490 2019
20
Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice. 61
31522685 2019
21
Fear-context association during memory retrieval requires input from granular to dysgranular retrosplenial cortex. 61
31201928 2019
22
LysargiNase enhances protein identification on the basis of trypsin on formalin-fixed paraffin-embedded samples. 61
31066118 2019
23
Cases of Argyria Associated With Colloidal Silver Use. 61
30957522 2019
24
Safety assessment of microsilver-loaded poly(methyl methacrylate) (PMMA) cement spacers in patients with prosthetic hip infections: Results of a prospective cohort study. 61
31537996 2019
25
Noninvasive Photoacoustic Imaging of Dendritic Cell Stimulated with Tumor Cell-Derived Exosome. 61
31385127 2019
26
Extracellular ATP promotes breast cancer invasion and epithelial-mesenchymal transition via hypoxia-inducible factor 2α signaling. 61
31148343 2019
27
Hippocampal damage and white matter lesions contribute to cognitive impairment in MPTP-lesioned mice with chronic cerebral hypoperfusion. 61
30959125 2019
28
Side-by-side Comparison of a Picosecond 755-nm Alexandrite Laser and a Quality-switched 1064-nm Neodymium-doped Yttrium Aluminum Garnet Laser in the Treatment of Argyria. 61
31423404 2019
29
[Silver coating on tumour prostheses]. 61
30927028 2019
30
Morphological and Molecular Identification of a New Ciliate, Zoothamnium palmphlatum nov. spec. (Ciliophora, Peritrichia) from North China. 61
30629314 2019
31
Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex. 61
31168614 2019
32
Spermatogenesis and lobular cyst type of testes organization in marine gastropod Littorina saxatilis (Olivi 1792). 61
30778731 2019
33
Astrocytic tau pathologies in aged human brain. 61
30937988 2019
34
Comparison of 18F-florbetaben quantification results using the standard Centiloid, MR-based, and MR-less CapAIBL® approaches: Validation against histopathology. 61
31101517 2019
35
Modification of outer membrane permeability and alteration of LPS in veterinary enterotoxigenic Escherichia coli. 61
31035220 2019
36
Purification of the Dendritic Filopodia-rich Fraction. 61
31107457 2019
37
Inhibitory effect of valproate sodium on pain behavior in diabetic mice involves suppression of spinal histone deacetylase 1 and inflammatory mediators. 61
30785087 2019
38
Identifying the Pathological Domain of Alpha- Synuclein as a Therapeutic for Parkinson's Disease. 61
31083520 2019
39
Genetic characterization and assessment of diversity in Pandharpuri buffalo breed of India using heterologous microsatellite markers. 61
31092100 2019
40
Delayed Contrast Enhancement in Magnetic Resonance Imaging and Vascular Morphology of Primary Diffuse Large B-Cell Lymphoma (DLBCL) of the Central Nervous System (CNS): A Retrospective Study. 61
31055591 2019
41
Ochronosis Presenting as Methemoglobinemia. 61
30229904 2019
42
Redescription of a Hymenostome Ciliate, Tetrahymena setosa (Protozoa, Ciliophora) Notes on its Molecular Phylogeny. 61
30099801 2019
43
Activation of the nuclear factor erythroid 2-related factor 2-antioxidant response element signal in rats with diffuse axonal injury. 61
30855558 2019
44
Fluorescent Silver Staining of Proteins in Polyacrylamide Gels. 61
31058890 2019
45
Sfrp5 interacts with Slurp1 to regulate the accumulation of triglycerides in hepatocyte steatosis model. 61
30879770 2019
46
Electron microscopy and tomography reveal that sodium 2-naphthalene sulfonate incorporated into perming solutions swells and tilts trichocyte intermediate filaments causing straightening of curly Japanese human hair. 61
30719733 2019
47
Cellulose acetate nanofibers embedded with AgNPs anchored TiO2 nanoparticles for long term excellent antibacterial applications. 61
30600049 2019
48
Characterization of Sample Loss Caused by Competitive Adsorption of Proteins in Vials Using Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis. 61
30813715 2019
49
Ribosomal DNA transcription in prefrontal pyramidal neurons is decreased in suicide. 61
30859295 2019
50
Human Atrial Natriuretic Peptide in Cold Storage of Donation After Circulatory Death Rat Livers: An Old but New Agent for Protecting Vascular Endothelia? 61
30461725 2019

Variations for Argyria

Expression for Argyria

Search GEO for disease gene expression data for Argyria.

Pathways for Argyria

GO Terms for Argyria

Sources for Argyria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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