MCID: ART010
MIFTS: 28

Arteriolosclerosis

Categories: Cardiovascular diseases

Aliases & Classifications for Arteriolosclerosis

MalaCards integrated aliases for Arteriolosclerosis:

Name: Arteriolosclerosis 12 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5162
ICD10 33 I70
MeSH 44 D050379
NCIt 50 C35543
SNOMED-CT 68 17941002
UMLS 73 C0878486

Summaries for Arteriolosclerosis

MalaCards based summary : Arteriolosclerosis is related to chronic kidney failure and iga glomerulonephritis. An important gene associated with Arteriolosclerosis is CD79A (CD79a Molecule). Affiliated tissues include brain, kidney and heart, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : 76 Arteriolosclerosis is a form of cardiovascular disease involving hardening and loss of elasticity of... more...

Related Diseases for Arteriolosclerosis

Diseases related to Arteriolosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 chronic kidney failure 29.3 ADIPOQ CD79A REN
2 iga glomerulonephritis 29.2 CD79A REN
3 kidney disease 29.1 C3 CD79A REN
4 acute maxillary sinusitis 10.5 C3 CD79A
5 hypersensitivity vasculitis 10.5 C3 CD79A
6 hypersensitivity reaction type iii disease 10.5 C3 CD79A
7 anemia, autoimmune hemolytic 10.4 C3 CD79A
8 autoimmune disease of blood 10.4 C3 CD79A
9 henoch-schoenlein purpura 10.4 C3 CD79A
10 chronic maxillary sinusitis 10.4 C3 CD79A
11 proliferative glomerulonephritis 10.4 C3 CD79A
12 membranoproliferative glomerulonephritis 10.3 C3 CD79A
13 degeneration of macula and posterior pole 10.2 C3 HTRA1
14 invasive aspergillosis 10.2 CABIN1 CD79A
15 cerebritis 10.1
16 cantu syndrome 10.0 ABCC9 TARDBP
17 aging 10.0
18 hypertensive retinopathy 10.0 ADIPOQ REN
19 membranous nephropathy 9.9 C3 CD79A
20 hypertension, essential 9.9
21 focal segmental glomerulosclerosis 1 9.9
22 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.9
23 focal segmental glomerulosclerosis 9.9
24 ischemia 9.9
25 retinitis 9.9
26 pyelitis 9.9 CD79A REN
27 apnea, obstructive sleep 9.9 ADIPOQ REN
28 diabetes mellitus 9.7
29 glomerulonephritis 9.7
30 hepatitis 9.7
31 heart disease 9.7
32 hypertensive heart disease 9.7
33 dementia 9.7
34 hyperglycemia 9.7
35 pyoderma 9.7
36 pyoderma gangrenosum 9.7
37 vascular dementia 9.7
38 obstructive jaundice 9.7 CD79A REN
39 sleep apnea 9.7 ADIPOQ REN
40 alport syndrome, x-linked 9.7 CD79A REN
41 glucose metabolism disease 9.7 ADIPOQ REN
42 arteries, anomalies of 9.5 ADIPOQ REN
43 orthostatic proteinuria 9.5 C3 CD79A REN
44 urinary system disease 9.3 CABIN1 CD79A REN
45 acquired metabolic disease 9.2 ADIPOQ REN

Graphical network of the top 20 diseases related to Arteriolosclerosis:



Diseases related to Arteriolosclerosis

Symptoms & Phenotypes for Arteriolosclerosis

MGI Mouse Phenotypes related to Arteriolosclerosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.8 ABCC9 ADIPOQ C3 HTRA1 REN TARDBP
2 hematopoietic system MP:0005397 9.73 ADIPOQ C3 CABIN1 CD79A REN TARDBP
3 immune system MP:0005387 9.63 ADIPOQ C3 CABIN1 CD79A REN TARDBP
4 muscle MP:0005369 9.35 ABCC9 ADIPOQ C3 REN TARDBP
5 renal/urinary system MP:0005367 8.92 CD79A REN ADIPOQ C3

Drugs & Therapeutics for Arteriolosclerosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pathophysiology of Martorell Hypertensive Ischemic Leg Ulcer (HYTILU) Recruiting NCT01578382

Search NIH Clinical Center for Arteriolosclerosis

Cochrane evidence based reviews: arteriolosclerosis

Genetic Tests for Arteriolosclerosis

Anatomical Context for Arteriolosclerosis

MalaCards organs/tissues related to Arteriolosclerosis:

41
Brain, Kidney, Heart, Spleen

Publications for Arteriolosclerosis

Articles related to Arteriolosclerosis:

(show top 50) (show all 64)
# Title Authors Year
1
A case of chronic ulcer due to subcutaneous arteriolosclerosis in an obese patient mimicking pyoderma gangrenosum. ( 29887980 )
2018
2
Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism. ( 28931619 )
2017
3
Long-term treatment with chaethomellic acid A reduces glomerulosclerosis and arteriolosclerosis in a rat model of chronic kidney disease. ( 29032332 )
2017
4
Relationship Between Type of Hypertension and Renal Arteriolosclerosis in Chronic Glomerular Disease. ( 27327274 )
2016
5
Letter by Kawada Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People". ( 27118795 )
2016
6
Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People. ( 26768207 )
2016
7
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. ( 26738751 )
2016
8
Response to Letter Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People". ( 27118794 )
2016
9
Hepatic Arteriolosclerosis: A Small-vessel Complication of Diabetes and Hypertension. ( 25786083 )
2015
10
Relationship between vascular function indexes, renal arteriolosclerosis, and renal clinical outcomes in chronic kidney disease. ( 25854541 )
2015
11
Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. ( 25289893 )
2014
12
Large blood pressure variability aggravates arteriolosclerosis and cortical sclerotic changes in the kidney in hypertensive rats. ( 24976508 )
2014
13
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. ( 24271328 )
2014
14
C3d deposition in the media of renal arterioles is a useful marker for arteriolosclerosis in IgA nephropathy. ( 24480433 )
2014
15
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. ( 24135527 )
2013
16
Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease. ( 22863782 )
2012
17
Stroke patients with cerebral microbleeds on MRI scans have arteriolosclerosis as well as systemic atherosclerosis. ( 22739424 )
2012
18
Severe intra- and periventricular hemorrhage: role of arteriolosclerosis related to maternal smoke. ( 21744137 )
2011
19
Postprandial hyperglycemia and hyperinsulinemia associated with renal arterio-arteriolosclerosis in chronic kidney disease. ( 20186145 )
2010
20
Martorell hypertensive ischemic leg ulcer: a model of ischemic subcutaneous arteriolosclerosis. ( 20855694 )
2010
21
Association between serum adiponectin levels and arteriolosclerosis in IgA nephropathy patients. ( 17443034 )
2007
22
Hyaline arteriolosclerosis: new meaning for an old lesion. ( 12631104 )
2003
23
Significance of white matter high intensity lesions as a predictor of stroke from arteriolosclerosis. ( 11971040 )
2002
24
Clinical picture of arteriolosclerosis. ( 11725387 )
2001
25
A clinical investigation on 30 cases of senile benign renal arteriolosclerosis treated by huang qi gu jing yin. ( 11789320 )
2001
26
Coronary reserve and arteriolosclerosis in hypertensive heart disease. ( 11151783 )
2000
27
Adverse effect of donor arteriolosclerosis on graft outcome after renal transplantation. ( 10809815 )
2000
28
Super long-term surviving two renal grafts with severe arteriolosclerosis and glomerulosclerosis. ( 11092352 )
2000
29
Severe renal arterio-arteriolosclerosis after cocaine use. ( 10069205 )
1999
30
Brain arteriolosclerosis and hemodynamic disturbance may induce leukoaraiosis. ( 10563635 )
1999
31
Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementia. ( 8929154 )
1996
32
Decrease of urine protein after treatment with probucol in patients with mild glomerulonephritis and arteriolosclerosis. ( 7477633 )
1995
33
Spontaneous coronary arteriolosclerosis in broiler chickens. ( 8357921 )
1993
34
Myoendothelial contacts in arteriolosclerosis. ( 1635004 )
1992
35
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. ( 2043948 )
1991
36
Arteriolosclerosis of the human renal allograft: morphology, origin, life history and relationship to cyclosporine therapy. ( 1899956 )
1991
37
Significance of renal hyaline arteriolosclerosis and tubulo-interstitial change in IgA glomerulonephropathy and focal glomerular sclerosis. ( 3696327 )
1987
38
Arteriolosclerosis in a cat. ( 3672816 )
1987
39
The pathogenesis of hyaline arteriolosclerosis. ( 2420184 )
1986
40
Renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. ( 3736745 )
1986
41
Significance of renal hyaline arteriolosclerosis in focal segmental glomerulosclerosis. ( 3897888 )
1985
42
The distribution of arteriolosclerosis along the arterioles in DOCA hypertensive rats. ( 6627747 )
1983
43
Histophysical and histochemical investigations on muscle arterioles in hypertensive arteriolosclerosis; an interference microscopical, polarization optical and histophotometrical study. ( 104533 )
1978
44
The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriolosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. ( 884912 )
1977
45
Quantitative studies of the renal corpuscles IV. Determination of normal values in various age categories, and an analysis of the possible influence of physiological degrees of arteriolosclerosis. ( 878873 )
1977
46
Hyaline arteriolosclerosis in wild animals. ( 4194799 )
1970
47
Hypertension with arteriolosclerosis in childhood: report of two cases. ( 6043880 )
1967
48
Retinal arteriolosclerosis in age, essential hypertension, and diabetes mellitus. ( 5964940 )
1966
49
"EXUDATIVE" LESIONS IN GLOMERULI OF CHILDREN: ? A VARIANT OF HYALINE ARTERIOLOSCLEROSIS. ( 14280313 )
1965
50
CONSIDERATIONS REGARDING THE PATHOGENESIS OF ARTERIOLOSCLEROSIS IN THE PULMONARY AND SYSTEMIC VASCULAR BED. ( 14295713 )
1964

Variations for Arteriolosclerosis

Expression for Arteriolosclerosis

Search GEO for disease gene expression data for Arteriolosclerosis.

Pathways for Arteriolosclerosis

GO Terms for Arteriolosclerosis

Biological processes related to Arteriolosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to drug GO:0035690 8.96 ADIPOQ REN
2 response to drug GO:0042493 8.8 ABCC9 ADIPOQ REN

Molecular functions related to Arteriolosclerosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.8 ADIPOQ C3 REN

Sources for Arteriolosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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