MCID: ART110
MIFTS: 31

Arteritic Anterior Ischemic Optic Neuropathy

Categories: Neuronal diseases, Eye diseases

Aliases & Classifications for Arteritic Anterior Ischemic Optic Neuropathy

MalaCards integrated aliases for Arteritic Anterior Ischemic Optic Neuropathy:

Name: Arteritic Anterior Ischemic Optic Neuropathy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050863

Summaries for Arteritic Anterior Ischemic Optic Neuropathy

MalaCards based summary : Arteritic Anterior Ischemic Optic Neuropathy is related to nonarteritic anterior ischemic optic neuropathy and retinal artery occlusion. An important gene associated with Arteritic Anterior Ischemic Optic Neuropathy is ITGB3 (Integrin Subunit Beta 3), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Folate Metabolism. Affiliated tissues include eye, neutrophil and endothelial.

Related Diseases for Arteritic Anterior Ischemic Optic Neuropathy

Diseases related to Arteritic Anterior Ischemic Optic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 nonarteritic anterior ischemic optic neuropathy 32.7 ACE F2 F5 GP1BA MTHFR NOS3
2 retinal artery occlusion 31.0 F2 F5 MTHFR
3 central retinal vein occlusion 31.0 F2 F5 MTHFR
4 retinal vein occlusion 31.0 F2 F5 MTHFR
5 antiphospholipid syndrome 30.9 F2 F5 MTHFR
6 sleep apnea 30.2 ACE CRP NOS3
7 retinal vascular occlusion 30.1 F2 F5 FANCG MTHFR
8 ischemic optic neuropathy 27.8 3.8-1.2 ACE F2 F5 GP1BA GSTM1
9 optic nerve disease 11.0
10 neuropathy 11.0
11 fetal and neonatal alloimmune thrombocytopenia 11.0 GP1BA ITGB3
12 inferior vena cava interruption 10.9 F5 MTHFR
13 amaurosis fugax 10.9 F5 MTHFR
14 hemifacial spasm 10.9 MTHFR NOS3
15 paracetamol poisoning 10.8 F2 F5
16 sticky platelet syndrome 10.8 F5 ITGB3
17 mesenteric vascular occlusion 10.8 F2 MTHFR
18 cerebral sinovenous thrombosis 10.7 F2 F5
19 hepatoportal sclerosis 10.7 ACE F2
20 blood protein disease 10.7 F2 MTHFR
21 hearing loss, noise-induced 10.7 GSTM1 GSTT1
22 renal artery disease 10.7 ACE NOS3
23 inherited blood coagulation disease 10.7 F2 GP1BA ITGB3
24 cerebral atherosclerosis 10.6 ACE MTHFR
25 hemoglobin e disease 10.6 F2 F5
26 coenurosis 10.6 F2 MT-ND1
27 spinal cord infarction 10.6 F2 F5 MTHFR
28 livedoid vasculopathy 10.6 F2 F5 MTHFR
29 prothrombin deficiency, congenital 10.6 F2 F5
30 cryptogenic cirrhosis 10.6 F2 F5 MTHFR
31 sister chromatid exchange, frequency of 10.6 GSTM1 GSTT1
32 porencephaly 10.6 F2 F5 MTHFR
33 thrombophlebitis 10.6 F2 F5 MTHFR
34 antithrombin iii deficiency 10.6 F2 F5 MTHFR
35 glanzmann thrombasthenia 10.6 F2 GP1BA ITGB3
36 portal vein thrombosis 10.6 F2 F5 MTHFR
37 buerger disease 10.6 F2 MTHFR NOS3
38 patent foramen ovale 10.6 F2 F5 MTHFR
39 blood platelet disease 10.6 F2 GP1BA ITGB3
40 von willebrand's disease 10.6 F2 F5 GP1BA
41 protein s deficiency 10.6 F2 F5 MTHFR
42 vein disease 10.6 F2 F5 MTHFR
43 placental abruption 10.6 F2 F5 MTHFR
44 protein c deficiency 10.6 F2 F5 MTHFR
45 intracranial hypertension 10.6 F2 F5 MTHFR
46 sagittal sinus thrombosis 10.6 F2 F5
47 hepatic vascular disease 10.6 F2 MTHFR NOS3
48 thrombophilia due to activated protein c resistance 10.6 F2 F5 MTHFR
49 bernard-soulier syndrome 10.6 F2 GP1BA ITGB3
50 autosomal dominant macrothrombocytopenia 10.6 GP1BA ITGB3

Graphical network of the top 20 diseases related to Arteritic Anterior Ischemic Optic Neuropathy:



Diseases related to Arteritic Anterior Ischemic Optic Neuropathy

Symptoms & Phenotypes for Arteritic Anterior Ischemic Optic Neuropathy

Drugs & Therapeutics for Arteritic Anterior Ischemic Optic Neuropathy

Search Clinical Trials , NIH Clinical Center for Arteritic Anterior Ischemic Optic Neuropathy

Genetic Tests for Arteritic Anterior Ischemic Optic Neuropathy

Anatomical Context for Arteritic Anterior Ischemic Optic Neuropathy

MalaCards organs/tissues related to Arteritic Anterior Ischemic Optic Neuropathy:

41
Eye, Neutrophil, Endothelial

Publications for Arteritic Anterior Ischemic Optic Neuropathy

Articles related to Arteritic Anterior Ischemic Optic Neuropathy:

(show top 50) (show all 93)
# Title Authors Year
1
Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) corresponds to visual function. ( 29953490 )
2018
2
The polymorphisms of ATOH 7, ET-1 and ACE in non-arteritic anterior ischemic optic neuropathy. ( 29792847 )
2018
3
Anomalous coagulation factors in non-arteritic anterior ischemic optic neuropathy with central retinal vein occlusion: A case report. ( 29642215 )
2018
4
The Association Between Phosphodiesterase Type 5 Inhibitor Use and Risk of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis. ( 29884471 )
2018
5
The Effect of Combined Systemic Erythropoietin and Steroid on Non-arteritic Anterior Ischemic Optic Neuropathy: A Prospective Study. ( 28632028 )
2017
6
High-dose intravenous pulse steroid therapy for optic disc swelling and subretinal fluid in non-arteritic anterior ischemic optic neuropathy. ( 28303068 )
2017
7
Optical coherence tomography angiography in acute arteritic and non-arteritic anterior ischemic optic neuropathy. ( 28861697 )
2017
8
Atrial fibrillation in retinal vascular occlusion disease and non-arteritic anterior ischemic optic neuropathy. ( 28771491 )
2017
9
Bilateral Arteritic Anterior Ischemic Optic Neuropathy Associated with Giant Cell Arteritis in Korea. ( 28994270 )
2017
10
Comparison of Optic Nerve Head Morphology in Patients with Primary Open Angle Glaucoma and Non-Arteritic Anterior Ischemic Optic Neuropathy. ( 29485789 )
2017
11
Visual outcome following bilateral non-arteritic anterior ischemic optic neuropathy: a systematic review and meta-analysis. ( 28836961 )
2017
12
Postural effects on intraocular pressure and ocular perfusion pressure in patients with non-arteritic anterior ischemic optic neuropathy. ( 28427356 )
2017
13
Giant cell arteritis with arteritic anterior ischemic optic neuropathy. ( 28523333 )
2017
14
A case of non-arteritic anterior ischemic optic neuropathy after completion of Harvoni therapy. ( 29260058 )
2017
15
Sequential development of non-arteritic anterior ischemic optic neuropathy in a patient on hemodialysis. ( 28944153 )
2017
16
OCT angiography of acute non-arteritic anterior ischemic optic neuropathy. ( 28117076 )
2017
17
Optical coherence tomography angiography of optic disc perfusion in non-arteritic anterior ischemic optic neuropathy. ( 28944200 )
2017
18
Arteritic Anterior Ischemic Optic Neuropathy Associated with Giant Cell Arteritis in an Elderly Korean Man. ( 27247526 )
2016
19
The effect of high-dose steroids, and normobaric oxygen therapy, on recent onset non-arteritic anterior ischemic optic neuropathy: a randomized clinical trial. ( 27510295 )
2016
20
Non arteritic anterior ischemic optic neuropathy; does Anticoagulation help? ( 28586576 )
2016
21
Analysis of optic disc damage by optical coherence tomography in terms of therapy in non-arteritic anterior ischemic optic neuropathy. ( 27672604 )
2016
22
Temporal Arteritis With Arteritic Anterior Ischemic Optic Neuropathy is Bilateral Until Proven Otherwise: Response. ( 27855129 )
2016
23
Clinical and color Doppler imaging features of one patient with occult giant cell arteritis presenting arteritic anterior ischemic optic neuropathy. ( 27516038 )
2016
24
Early macular ganglion cell-inner plexiform layer analysis in non-arteritic anterior ischemic optic neuropathy. ( 26631135 )
2016
25
Neutrophil-to-Lymphocyte Ratio and Non-arteritic Anterior Ischemic Optic Neuropathy. ( 27761294 )
2016
26
Giant Cell Arteritis With Arteritic Anterior Ischemic Optic Neuropathy Is Bilateral Until Proven Otherwise. ( 27855128 )
2016
27
Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): A Review and Update on Animal Models. ( 26959135 )
2016
28
Increased Risk of Stroke in Patients with Non-arteritic Anterior Ischemic Optic Neuropathy: A Nationwide Retrospective Cohort Study. ( 27521605 )
2016
29
Choroidal thickness in Chinese patients with non-arteritic anterior ischemic optic neuropathy. ( 27580594 )
2016
30
Could Topical Minoxidil Cause Non-Arteritic Anterior Ischemic Optic Neuropathy? ( 27656541 )
2016
31
Retinal Ganglion Cell Layer Thinning Within One Month of Presentation for Non-Arteritic Anterior Ischemic Optic Neuropathy. ( 27388052 )
2016
32
Delayed non-arteritic anterior ischemic optic neuropathy following acute primary angle closure. ( 26028953 )
2015
33
Intravitreal injection of a Rho-kinase inhibitor (fasudil) for recent onset non-arteritic anterior ischemic optic neuropathy. ( 26444290 )
2015
34
Cataract surgery as a risk factor for non-arteritic anterior ischemic optic neuropathy and the intra-operative use of intravitreal corticosteroid. ( 26622149 )
2015
35
Acute Monocular Blindness after Carotid Endarterectomy due to Non-arteritic Anterior Ischemic Optic Neuropathy. ( 26286388 )
2015
36
Corticosteroid therapy in patients with non-arteritic anterior ischemic optic neuropathy. ( 26040070 )
2015
37
Choroidal thickness in non-arteritic anterior ischemic optic neuropathy. ( 25488646 )
2015
38
Protective effects of systemic treatment with methylprednisolone in a rodent model of non-arteritic anterior ischemic optic neuropathy (rAION). ( 25543054 )
2015
39
Steroid-induced central serous chorioretinopathy in a patient with non-arteritic anterior ischemic optic neuropathy. ( 26155086 )
2015
40
Macular star formation in diabetic patients with non-arteritic anterior ischemic optic neuropathy (NA-AION). ( 25859144 )
2015
41
Obstructive sleep apnea syndrome and non-arteritic anterior ischemic optic neuropathy: a case control study. ( 26913263 )
2015
42
Differences between Non-arteritic Anterior Ischemic Optic Neuropathy and Open Angle Glaucoma with Altitudinal Visual Field Defect. ( 26635459 )
2015
43
Glutathione-S-Transferase Deletions and Non-arteritic Anterior Ischemic Optic Neuropathy. ( 25990411 )
2015
44
Change of Retinal Nerve Layer Thickness in Non-Arteritic Anterior Ischemic Optic Neuropathy Revealed by Fourier Domain Optical Coherence Tomography. ( 26580572 )
2015
45
Neutrophil-to-Lymphocyte Ratio as a Marker in Patients with Non-arteritic Anterior Ischemic Optic Neuropathy. ( 26740898 )
2015
46
Translational Preclinical Research may Lead to Improved Medical Management of Non-Arteritic Anterior Ischemic Optic Neuropathy. ( 25071709 )
2014
47
Choroidal Thickness in Non-Arteritic Anterior Ischemic Optic Neuropathy. ( 25217855 )
2014
48
Assessment of functional and morphometric endpoints in patients with non-arteritic anterior ischemic optic neuropathy (NAION). ( 24477537 )
2014
49
Subretinal fluid is common in experimental non-arteritic anterior ischemic optic neuropathy. ( 25257770 )
2014
50
Visual outcome of mega-dose intravenous corticosteroid treatment in non-arteritic anterior ischemic optic neuropathy - retrospective analysis. ( 24886579 )
2014

Variations for Arteritic Anterior Ischemic Optic Neuropathy

Expression for Arteritic Anterior Ischemic Optic Neuropathy

Search GEO for disease gene expression data for Arteritic Anterior Ischemic Optic Neuropathy.

Pathways for Arteritic Anterior Ischemic Optic Neuropathy

Pathways related to Arteritic Anterior Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.3 F2 F5 GP1BA ITGB3 LEFTY2 NOS3
2
Show member pathways
12 CRP F2 MPO MTHFR
3 11.78 GP1BA ITGB3 NOS3
4
Show member pathways
11.76 F2 F5 GP1BA PRTN3
5 11.74 GP1BA ITGB3 MPO
6
Show member pathways
11.62 F2 GP1BA ITGB3
7 11.6 GSTM1 GSTT1 ITGB3 NOS3
8 11.47 GSTM1 MPO PRTN3
9 10.65 GSTT1 MPO
10 10.59 GSTM1 GSTT1 MPO
11 10.55 NOS3 PDE5A
12 10.1 GSTM1 MPO

GO Terms for Arteritic Anterior Ischemic Optic Neuropathy

Cellular components related to Arteritic Anterior Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.17 ACE CRP F2 F5 LEFTY2 MPO

Biological processes related to Arteritic Anterior Ischemic Optic Neuropathy according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.65 F5 ITGB3 LEFTY2
2 platelet activation GO:0030168 9.61 F2 GP1BA ITGB3
3 glutathione derivative biosynthetic process GO:1901687 9.51 GSTM1 GSTT1
4 fibrinolysis GO:0042730 9.49 F2 GP1BA
5 blood coagulation, intrinsic pathway GO:0007597 9.46 F2 GP1BA
6 removal of superoxide radicals GO:0019430 9.4 MPO NOS3
7 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.37 CRP ITGB3
8 regulation of blood coagulation GO:0030193 9.32 F2 GP1BA
9 negative regulation of lipid storage GO:0010888 9.26 CRP ITGB3
10 negative regulation of platelet activation GO:0010544 9.16 F2 NOS3
11 hemostasis GO:0007599 9.13 F2 F5 GP1BA
12 blood coagulation GO:0007596 9.02 F2 F5 GP1BA ITGB3 PRTN3

Sources for Arteritic Anterior Ischemic Optic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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