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MCID: ART022
MIFTS: 76

Arthritis

Categories: Bone diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Arthritis

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MalaCards integrated aliases for Arthritis:

Name: Arthritis 38 12 76 29 55 43 3 44 15 73
Inflammatory Joint Disease 55 73
Inflammatory Disorder of Joint 12

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:848
MeSH 44 D001168
NCIt 50 C2883
Sources

Summaries for Arthritis

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MedlinePlus : 43 If you feel pain and stiffness in your body or have trouble moving around, you might have arthritis. Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Over time, a swollen joint can become severely damaged. Some kinds of arthritis can also cause problems in your organs, such as your eyes or skin. Types of arthritis include Osteoarthritis is the most common type of arthritis. It's often related to aging or to an injury. Autoimmune arthritis happens when your body's immune system attacks healthy cells in your body by mistake. Rheumatoid arthritis is the most common form of this kind of arthritis. Juvenile arthritis is a type of arthritis that happens in children. Infectious arthritis is an infection that has spread from another part of the body to the joint. Psoriatic arthritis affects people with psoriasis. Gout is a painful type of arthritis that happens when too much uric acid builds up in the body. It often starts in the big toe. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

MalaCards based summary : Arthritis, also known as inflammatory joint disease, is related to juvenile rheumatoid arthritis and rheumatoid arthritis, systemic juvenile, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthritis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Rayos and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include joint, skin over the joint and bone, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

CDC : 3 Arthritis affects 54.4 million US adults, more than 1 of 4. It is a major cause of work disability in the United States and one of the most common chronic conditions in the nation. Arthritis is a common cause of chronic pain.

Disease Ontology : 12 A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located in joint and/or redness located in skin over the joint.

Wikipedia : 76 Arthritis is a term often used to mean any disorder that affects joints.Symptoms generally include joint... more...

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Related Diseases for Arthritis

About this section

Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1327)
# Related Disease Score Top Affiliating Genes
1 juvenile rheumatoid arthritis 35.7 IL1B IL6 LTA TNF
2 rheumatoid arthritis, systemic juvenile 35.4 IL6 LACC1 MIF
3 systemic onset juvenile idiopathic arthritis 35.1 IL1B TNF
4 oligoarticular juvenile idiopathic arthritis 35.0 MIF PTPN22 TNF
5 spondyloarthropathy 1 34.6 IL17A MMP3 TNF
6 polyarticular onset juvenile idiopathic arthritis 34.5 TNFRSF11A TNFSF11
7 psoriatic arthritis 34.4 IL17A IL1A IL1B IL6 LTA MMP1
8 adult-onset still's disease 33.9 IL1B IL6 MIF TNF
9 rheumatoid lung disease 33.8 IL17A MMP3 TNF
10 palindromic rheumatism 33.7 IL1B PTPN22 TNF
11 osteoarthritis 33.5 IL1B IL6 MMP1 MMP13 MMP3 TNF
12 lyme disease 33.4 IL17A IL1B IL6 TNF
13 rheumatoid nodulosis 33.3 MMP3 MMP9
14 temporal arteritis 33.3 CCL2 IL6 PTPN22
15 scleritis 33.2 CCL2 MMP9 TNF
16 rosacea 33.1 IL6 MMP9 TNF
17 crohn's disease 33.1 IL1B IL6 LACC1 TNF
18 joint disorders 33.1 IL17A IL1B IL6 MMP3 TNF TNFSF11
19 familial mediterranean fever 33.0 IL1B PSTPIP1 SAA1 TNF
20 systemic lupus erythematosus 33.0 CCL2 IL17A IL6 LTA PTPN22 TNF
21 brucellosis 32.8 CXCL8 IL6 SAA1 TNF
22 bronchiolitis obliterans 32.8 CXCL8 IL17A IL6 MMP9 TNF
23 psoriasis 32.6 CCL2 CXCL8 IL17A IL1A IL1B IL6
24 tropical spastic paraparesis 32.5 IL17A IL6 MMP9
25 behcet syndrome 32.4 CXCL8 IL17A IL1B IL6 LTA PSTPIP1
26 interstitial lung disease 32.4 CCL2 CXCL8 IL1A IL1B IL6 MMP9
27 sarcoidosis 1 32.4 CCL2 IL1B LTA MIF TNF
28 spondylitis 32.3 IL17A IL6 LTA TNF
29 osteoporosis 32.3 IL1A IL1B IL6 MMP3 TNF TNFRSF11A
30 bone disease 32.3 IL1B IL6 MMP13 TNF TNFRSF11A TNFSF11
31 uveitis 32.0 CCL2 IL17A IL1A TNF
32 spondyloarthropathy 31.9 IL17A IL6 MMP3 TNF TNFSF11
33 chlamydia 31.8 CXCL8 IL1B IL6 TNF
34 anterior uveitis 31.7 CCL2 IL6 PTPN22
35 pericarditis 31.7 IL1B IL6 TNF
36 rheumatoid arthritis 31.7 CCL2 CXCL8 IL17A IL1A IL1B IL6
37 chikungunya 31.6 CCL2 IL1B IL6 TNF
38 pneumonia 31.6 CCL2 CXCL8 IL1B IL6 TNF
39 autoimmune disease 31.5 IL17A IL1B IL6 PTPN22 TNF
40 pyoderma gangrenosum 31.5 CXCL8 PSTPIP1 TNF
41 lung disease 31.5 CCL2 CXCL8 IL1B MMP9 TNF
42 fasciitis 31.4 CXCL8 IL6 TNF
43 pyoderma 31.4 CXCL8 MMP1 PSTPIP1 TNF
44 laryngitis 31.4 IL1B IL6 TNF
45 osteomyelitis 31.3 CXCL8 IL1A IL1B IL6 TNF TNFSF11
46 kawasaki disease 31.3 CCL2 IL6 MMP3 MMP9 TNF
47 myelitis 31.2 IL17A IL6 TNF
48 synovitis 31.2 CXCL8 IL1B IL6 MMP1 MMP13 MMP3
49 haemophilus influenzae 31.2 CXCL8 IL1B TNF
50 colitis 31.2 CXCL8 IL17A IL1B IL6 LACC1 TNF

Graphical network of the top 20 diseases related to Arthritis:



Diseases related to Arthritis
Sources

Symptoms & Phenotypes for Arthritis

About this section

UMLS symptoms related to Arthritis:


arthralgia, back pain, metatarsalgia, muscle cramp, sciatica, joint stiffness

GenomeRNAi Phenotypes related to Arthritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression GR00224-A-2 8.8 IL1A MMP13 MMP9

MGI Mouse Phenotypes related to Arthritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.27 TNFRSF11A TNFSF11 PTPN22 SAA1 TNF IL6
2 hematopoietic system MP:0005397 10.25 TNFRSF11A TNFSF11 PTPN22 TNF MMP3 IL6
3 immune system MP:0005387 10.25 TNFAIP6 TNFRSF11A TNFSF11 TNF IL6 MMP9
4 integument MP:0010771 9.86 TNF TNFRSF11A TNFSF11 IL1B IL6 MMP9
5 neoplasm MP:0002006 9.81 TNFRSF11A TNFSF11 TNF IL6 MMP9 MIF
6 respiratory system MP:0005388 9.61 TNF TNFAIP6 TNFRSF11A TNFSF11 PTPN22 IL6
7 skeleton MP:0005390 9.32 TNF TNFRSF11A TNFSF11 IL1B MMP3 IL6
Sources

Drugs & Therapeutics for Arthritis

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FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Rayos 18 PREDNISONE Horizon Pharma July of 2012

Drugs for Arthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 986)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1959-05-2, 59-05-2 126941
2
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75706-12-6 3899
3
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 185243-69-0
4
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 332348-12-6 10237
5
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
6
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
7
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 174722-31-7 10201696
8
Hydroxychloroquine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 118-42-3 3652
9
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83-43-2 6741
10
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 16590-41-3 5360515
11
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
12
Sulfasalazine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 599-79-1 5353980 5359476
13
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 104987-11-3 445643 439492
14
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 15307-86-5 3033
15
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 202409-33-4 123619
16
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
17
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2216-51-5 16666
18
Cimetidine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 51481-61-9 2756
19
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
20
Spironolactone Approved Phase 4,Phase 2 1952-01-7, 52-01-7 5833
21
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 169590-42-5 2662
22
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
23
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22204-53-1 1302 156391
24
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 9004-61-9 53477741
25
Dimethyl fumarate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 624-49-7 5271565 637568
26
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7440-66-6 23994
27
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
28
Polidocanol Approved Phase 4 9002-92-0
29
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
30
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 53-03-2 5865
31
Azathioprine Approved Phase 4,Phase 3,Phase 2 446-86-6 2265
32
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
33
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
34
Iron Approved Phase 4,Phase 1,Phase 2,Not Applicable 7439-89-6 23925
35
Rivaroxaban Approved Phase 4,Phase 3,Not Applicable 366789-02-8
36
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
37
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
38
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
39
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 71273 175805
40
Hyoscyamine Approved Phase 4 101-31-5 64692
41
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
42
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260
43
Everolimus Approved Phase 4,Phase 1,Phase 2 159351-69-6 6442177
44
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 22916-47-8 4189
45
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 128794-94-5 5281078
46
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 24280-93-1 446541
47
Sirolimus Approved, Investigational Phase 4,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
48
Calcium Carbonate Approved, Investigational Phase 4,Phase 3,Phase 2 471-34-1
49
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-18-0, 6055-19-2 2907
50
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816

Interventional clinical trials:

(show top 50) (show all 7117)
# Name Status NCT ID Phase Drugs
1 Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis Unknown status NCT02087696 Phase 4 Tocilizumab
2 Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic Arthritis Unknown status NCT01939132 Phase 4 Open label H.P. Acthar Gel
3 Efficacy Study of Leflunomide to Treat Juvenile Idiopathic Arthritis Unknown status NCT02024334 Phase 4 Leflunomide
4 Etanercept and Methotrexate in Patients to Induce Remission in Early Arthritis (EMPIRE) Unknown status NCT01303874 Phase 4 Etanercept (ETN);Placebo
5 Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis Unknown status NCT01000441 Phase 4 infliximab, etanercept, adalimumab;abatacept, rituximab or tocilizumab
6 Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis Unknown status NCT00291915 Phase 4 Adalimumab;Methotrexate
7 Effectiveness of Iguratimod Versus Placebo to Treat Early Rheumatoid Arthritis on MRI Unknown status NCT01893151 Phase 4 Iguratimod;Iguratimod placebo
8 Long-term Efficacy of Iguratimod Alone or Iguratimod in Combination With Methotrexate in Patients With Rheumatoid Arthritis Unknown status NCT01548001 Phase 4 Iguratimod;Methotrexate
9 Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis Unknown status NCT01301703 Phase 4
10 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
11 Withdrawal of Etanercept After Successful Treatment of Juvenile Idiopathic Arthritis Unknown status NCT01287715 Phase 4 etanercept;etanercept
12 TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis Unknown status NCT00908089 Phase 4 Trexan+Salazopyrin+Oxiklorin+prednisolone + infliximab;Trexan+Salazopyrin+Oxiklorin+prednisolone + placebo
13 Study of Iguratimod Plus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheumatoid Arthritis Unknown status NCT02275299 Phase 4 Iguratimod;Leflunomide;Methotrexate
14 Remission Induction in Very Early Rheumatoid Arthritis Unknown status NCT00523692 Phase 4 Etanercept, methotrexate and depomedrone;depemedrone
15 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
16 Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis Unknown status NCT01002716 Phase 4
17 The Clinical Efficacy and Safety of Tacrolimus in Refractory Rheumatoid Arthritis Patients for 6 Months Treatment Unknown status NCT02837978 Phase 4 Tacrolimus;MTX
18 REstore Working Ability in RheumatoiD Arthritis Unknown status NCT01405326 Phase 4
19 Comparison of the Effect of Etoricoxib and Diclofenac on Early Morning Activity in Rheumatoid Arthritis (RA) Unknown status NCT01067430 Phase 4 Etoricoxib;Diclofenac
20 Clinical Study to Evaluate the Efficacy of Anakinra in Patients With Rheumatoid Arthritis and Diabetes Unknown status NCT02236481 Phase 4 Anakinra;TNF alpha inhibitors
21 Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker Unknown status NCT01072058 Phase 4 TNF blockers (infliximab, adalimumab, etanercept)
22 Rheumatoid Arthritis Patients in Training Unknown status NCT00434200 Phase 4
23 Evaluation Effects of Treatment With IL-6R Inhibitor on Clinical Response and Biomarkers in Patients With Rheumatoid Arthritis (RA) Not Responding to DMARDs and/or a First Biological Agent. Unknown status NCT01835613 Phase 4
24 Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Unknown status NCT02132234 Phase 4 Etanercept;Adalimumab;Certolizumab;Infliximab
25 Ultrasonographic Monitoring of Response to Infliximab in Patients With Rheumatoid Arthritis Unknown status NCT01282528 Phase 4
26 Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis Unknown status NCT00216177 Phase 4 Infliximab;Adalimumab
27 Effect of Tocilizumab to the Cellular Immune Response to Influenza Vaccine Unknown status NCT01980836 Phase 4
28 Bucillamine Study of Holding Remission After Infliximab Dose-off Unknown status NCT00716248 Phase 4 bucillamine;methotrexate
29 Very Early Versus Delayed Etanercept in Patients With RA Unknown status NCT02433184 Phase 4 Etanercept;Methotrexate;Sulfasalazine;Hydroxychloroquine;Etanercept;Methotrexate
30 Efficacy and Safety of Adalimumab 80 mg Every Other Week With Methotrexate Unknown status NCT01270035 Phase 4 Adalimumab
31 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
32 Gait Analysis of Ankle Arthroplasty and Arthrodesis Unknown status NCT00921076 Phase 4
33 Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis Unknown status NCT01223976 Phase 4
34 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
35 Corticosteroids as Additive in Temporomandibular Joint (TMJ) Arthrocentesis Unknown status NCT01275014 Phase 4 Dexamethasone;Isotonic saline
36 The Long-term Evaluation of Glucosamine Sulphate Study Unknown status NCT00513422 Phase 4
37 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4 spironolactone
38 The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy Unknown status NCT02539069 Phase 4
39 The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) Unknown status NCT02539056 Phase 4
40 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
41 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4 Imrecoxib
42 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4 Guli capsule;Kangguzengsheng capsule
43 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
44 Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection Unknown status NCT02539095 Phase 4
45 Comparison of Efficacy and Safety of Microfracture and Modified Microfracture Unknown status NCT02539030 Phase 4
46 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
47 The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Unknown status NCT00422643 Phase 4 Sodium hyaluronate (hyaluronic acid)
48 The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis Unknown status NCT01088165 Phase 4 Adalimumab treatment arm;Fumaric acid esters treatment group
49 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
50 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4

Search NIH Clinical Center for Arthritis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Arthritis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Arthritis:
AlloStem
Embryonic/Adult Cultured Cells Related to Arthritis:
Adipose-derived mesenchymal stem cells combined with allograft bone (AlloStem PMIDs: 22500696

Cochrane evidence based reviews: arthritis

Sources

Genetic Tests for Arthritis

About this section

Genetic tests related to Arthritis:

# Genetic test Affiliating Genes
1 Arthritis 29
Sources

Anatomical Context for Arthritis

About this section

The Foundational Model of Anatomy Ontology organs/tissues related to Arthritis:

19
Joint, Skin Over The Joint

MalaCards organs/tissues related to Arthritis:

41
Bone, T Cells, Testes, Skin, Eye, Endothelial, B Cells
Sources

Publications for Arthritis

About this section

Articles related to Arthritis:

(show top 50) (show all 17121)
# Title Authors Year
1
Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis. ( 29070531 )
2018
2
miR-522 Modulated the Expression of Proinflammatory Cytokines and Matrix Metalloproteinases Partly via Targeting Suppressor of Cytokine Signaling 3 in Rheumatoid Arthritis Synovial Fibroblasts. ( 29394098 )
2018
3
Discitis caused by rat bite fever in a rheumatoid arthritis patient on tocilizumab-first ever case. ( 29522179 )
2018
4
"STATus of STAT3 in Psoriatic Arthritis." ( 29439293 )
2018
5
The DNA methylation landscape of CD4<sup>+</sup>T cells in oligoarticular juvenile idiopathic arthritis. ( 28969936 )
2018
6
The association between caspase-5 gene polymorphisms and rheumatoid arthritis in a Chinese population. ( 29158166 )
2018
7
Association of heterogeneity of the thyroid gland with matrix metalloproteinase-3 in rheumatoid arthritis patients with Hashimoto's thyroiditis. ( 29442475 )
2018
8
Bacteremia and Septic Arthritis due to a Nontoxigenic Strain of<i>Clostridium difficile</i>in a Patient With Sickle Cell Disease. ( 29410974 )
2018
9
Usefulness of tocilizumab for treating rheumatoid arthritis with myelodysplastic syndrome: A case report and literature review. ( 29924032 )
2018
10
HMGB proteins and arthritis. ( 28916968 )
2018
11
Minimal Disease Activity among Active Psoriatic Arthritis Patients Treated with Secukinumab: 2-year Results from the FUTURE 2 Study. ( 29409133 )
2018
12
Rituximab therapy in rheumatoid arthritis and primary biliary cholangitis. ( 29338925 )
2018
13
Effect of Biologics on Fatigue in Psoriatic Arthritis: A Systematic Literature Review with Meta-analysis. ( 29452303 )
2018
14
Simultaneous Quadruple Joint Replacement (QJR) in Disabling Juvenile Rheumatoid Arthritis - a Case Report with Review of Literature. ( 29911143 )
2018
15
Chronic reactive arthritis associated with prostatitis caused by<i>Neisseria meningitidis</i>. ( 29374652 )
2018
16
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report. ( 29891129 )
2018
17
Causal association between rheumatoid arthritis and aA decreased risk of Alzheimer's disease : AA Mendelian randomization study. ( 29974225 )
2018
18
Involvement of M1/M2 macrophages in the pathomechanisms of intralymphatic histiocytosis associated with rheumatoid arthritis. ( 29905385 )
2018
19
Cost and Cost Effectiveness of Treatments for Psoriatic Arthritis: A Systematic Literature Review. ( 29441473 )
2018
20
Treatment Patterns Among Patients with Psoriatic Arthritis Treated with a Biologic in the United States: Descriptive Analyses from an Administrative Claims Database. ( 29952704 )
2018
21
Clinical, Imaging, and Pathological Suppression of Synovitis in Rheumatoid Arthritis: Is the Disease Curable? ( 29868592 )
2018
22
Burden of Depression among Working-Age Adults with Rheumatoid Arthritis. ( 29971163 )
2018
23
Enthesitis: A hallmark of psoriatic arthritis. ( 29429762 )
2018
24
Primary meningococcal arthritis as a presentation of nodal marginal zone lymphoma. ( 29367362 )
2018
25
Tetraspanin CD82 affects migration, attachment and invasion of rheumatoid arthritis synovial fibroblasts. ( 29980577 )
2018
26
Use of biological disease modifying antirheumatic drugs in rheumatoid arthritis in Austria from 2008 to 2011 : AA retrospective analysis of 72% of the population. ( 29445863 )
2018
27
A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients. ( 29973208 )
2018
28
Acute septic arthritis of the knee: A rare case report of infection with Parvimonas micra after an intra-articular corticosteroid injection for osteoarthritis. ( 29305995 )
2018
29
Physical Activity Assessment Using an Activity Tracker in Patients with Rheumatoid Arthritis and Axial Spondyloarthritis: Prospective Observational Study. ( 29295810 )
2018
30
Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab. ( 29485546 )
2018
31
High Adherence Observed to System-Level Performance Measures for Rheumatoid Arthritis in a National Early Arthritis Cohort Over 8 Years. ( 29450976 )
2018
32
Pain threshold and temporomandibular function in systemic sclerosis: comparison with psoriatic arthritis. ( 29445986 )
2018
33
Lipoma Arborescens Associated With Psoriatic Arthritis in an Adolescent Boy: A Case Report and Review of the Literature. ( 29933323 )
2018
34
Involvement of T helper 17 cells in inflammatory arthritis depends on the host intestinal microbiota. ( 29975009 )
2018
35
Increased Mortality and Reoperation Rates After Treatment for Septic Arthritis of the Knee in People Who Inject Drugs: Nationwide Inpatient Sample, 2000-2013. ( 29762153 )
2018
36
Association of single nucleotide polymorphisms in resistin gene with rheumatoid arthritis in a Chinese population. ( 29978502 )
2018
37
Incidental diagnosis of sternoclavicular septic arthritis with <i>Moraxella nonliquefaciens</i>. ( 29942746 )
2018
38
Association between anti-citrullinated alpha enolase antibodies and clinical features in a cohort of patients with rheumatoid arthritis: a pilot study. ( 29976039 )
2018
39
The subjective components of the Disease Activity Score 28-joints (DAS28) in rheumatoid arthritis patients and coexisting fibromyalgia. ( 29955927 )
2018
40
Psoriasis and the risk of foot and ankle tendinopathy or enthesopathy in the absence of psoriatic arthritis: a population-based study. ( 29862046 )
2018
41
Toxoplasmosis seroprevalence in rheumatoid arthritis patients: A systematic review and meta-analysis. ( 29870527 )
2018
42
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression. ( 29489833 )
2018
43
Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of <i>Staphylococcus aureus</i>-Induced Septic Arthritis. ( 29867945 )
2018
44
Folate Supplementation for Methotrexate Therapy in Patients With Rheumatoid Arthritis: A Systematic Review. ( 29975207 )
2018
45
Circulating levels of carbamylated protein and neutrophil extracellular traps are associated with periodontitis severity in patients with rheumatoid arthritis: A pilot case-control study. ( 29394286 )
2018
46
Predictors of Treatment Response in Rheumatoid Arthritis. ( 29981377 )
2018
47
Physiotherapists' Adoption of a Theory-Based Skills Training Program in Guiding People with Rheumatoid Arthritis to Health-Enhancing Physical Activity. ( 29971578 )
2018
48
Hypertrophic osteoarthropathy mimicking a reactive arthritis: a case report and review of the literature. ( 29759083 )
2018
49
Difficult diagnosis of heart failure in rheumatoid arthritis: six-year follow-up of constrictive pericarditis. ( 29558019 )
2018
50
Proteomics analysis reveals differential pattern of widespread protein expression and novel role of histidine-rich glycoprotein and lipopolysaccharide-binding protein in rheumatoid arthritis. ( 29246875 )
2018