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MCID: ART022
MIFTS: 77

Arthritis

Categories: Bone diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Arthritis

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MalaCards integrated aliases for Arthritis:

Name: Arthritis 38 12 76 29 55 43 3 44 15 73
Inflammatory Joint Disease 55 73
Inflammatory Disorder of Joint 12

Classifications:

MalaCards categories:
Anatomical: Bone diseases Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:848
MeSH 44 D001168
NCIt 50 C2883
SNOMED-CT 68 3723001
Sources

Summaries for Arthritis

About this section
MedlinePlus : 43 If you feel pain and stiffness in your body or have trouble moving around, you might have arthritis. Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Over time, a swollen joint can become severely damaged. Some kinds of arthritis can also cause problems in your organs, such as your eyes or skin. Types of arthritis include Osteoarthritis is the most common type of arthritis. It's often related to aging or to an injury. Autoimmune arthritis happens when your body's immune system attacks healthy cells in your body by mistake. Rheumatoid arthritis is the most common form of this kind of arthritis. Juvenile arthritis is a type of arthritis that happens in children. Infectious arthritis is an infection that has spread from another part of the body to the joint. Psoriatic arthritis affects people with psoriasis. Gout is a painful type of arthritis that happens when too much uric acid builds up in the body. It often starts in the big toe. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

MalaCards based summary : Arthritis, also known as inflammatory joint disease, is related to juvenile rheumatoid arthritis and septic arthritis, and has symptoms including joint stiffness, arthralgia and back pain. An important gene associated with Arthritis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Rayos and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include bone, t cells and lung, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

Disease Ontology : 12 A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located in joint and/or redness located in skin over the joint.

CDC : 3 Arthritis affects 54.4 million US adults, more than 1 of 4. It is a major cause of work disability in the United States and one of the most common chronic conditions in the nation. Arthritis is a common cause of chronic pain.

Wikipedia : 76 Arthritis is a term often used to mean any disorder that affects joints.Symptoms generally include joint... more...

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Related Diseases for Arthritis

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Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1565)
# Related Disease Score Top Affiliating Genes
1 juvenile rheumatoid arthritis 34.7 IL1B IL6 LTA TNF
2 septic arthritis 34.6 CXCL8 MMP1 MMP3
3 rheumatoid arthritis, systemic juvenile 34.3 IL6 LACC1 MIF
4 systemic onset juvenile idiopathic arthritis 34.3 MIF TNF
5 psoriatic arthritis 34.2 IL17A IL1A IL1B IL6 LTA MMP1
6 oligoarticular juvenile idiopathic arthritis 34.0 MIF PTPN22 TNF
7 spondyloarthropathy 1 33.8 IL17A MMP3 TNF
8 polyarticular onset juvenile idiopathic arthritis 33.7 TNFRSF11A TNFSF11
9 rheumatoid arthritis 33.5 CCL2 CXCL8 IL17A IL1A IL1B IL6
10 osteoarthritis 33.2 IL1B IL6 MMP1 MMP13 MMP3 TNF
11 adult-onset still's disease 32.9 IL1B IL6 MIF TNF
12 palindromic rheumatism 32.8 IL1B PTPN22 TNF
13 rheumatoid lung disease 32.7 IL17A IL1B MMP3 TNF
14 joint disorders 32.4 IL17A IL1B IL6 MMP3 TNF TNFSF11
15 psoriasis 32.4 CCL2 CXCL8 IL17A IL1A IL1B IL6
16 behcet syndrome 32.4 CXCL8 IL17A IL1B IL6 LTA PSTPIP1
17 lyme disease 32.3 IL17A IL1B IL6 MMP9 TNF
18 rheumatoid nodulosis 32.3 MMP3 MMP9
19 temporal arteritis 32.2 CCL2 IL6 PTPN22 TNF
20 rosacea 32.2 IL6 MMP9 TNF
21 scleritis 32.2 CCL2 MMP9 TNF
22 familial mediterranean fever 32.1 IL1B PSTPIP1 SAA1 TNF
23 systemic lupus erythematosus 32.1 CCL2 CXCL8 IL17A IL1B IL6 LTA
24 sarcoidosis 1 32.1 CCL2 IL1B LTA MIF TNF
25 bronchiolitis obliterans 32.1 CXCL8 IL17A IL6 MMP9 TNF
26 interstitial lung disease 32.1 CCL2 CXCL8 IL1A IL1B IL6 MMP9
27 brucellosis 32.0 CXCL8 IL6 SAA1 TNF
28 osteoporosis 32.0 IL1A IL1B IL6 MMP3 TNF TNFRSF11A
29 bone disease 31.9 IL1B IL6 MMP13 TNF TNFRSF11A TNFSF11
30 tropical spastic paraparesis 31.7 IL17A IL6 MMP9
31 spondylitis 31.4 IL17A IL6 LTA TNF
32 uveitis 31.2 CCL2 IL17A IL1A TNF
33 synovitis 31.1 CXCL8 IL1B IL6 MMP1 MMP13 MMP3
34 spondyloarthropathy 30.9 IL17A IL6 MMP3 TNF TNFSF11
35 lung disease 30.9 CCL2 CXCL8 IL17A IL1B IL6 MMP9
36 chlamydia 30.9 CXCL8 IL1A IL1B IL6 TNF
37 pneumonia 30.9 CCL2 CXCL8 IL1B IL6 TNF
38 osteomyelitis 30.9 CXCL8 IL1A IL1B IL6 TNF TNFSF11
39 pericarditis 30.9 IL1B IL6 TNF
40 chikungunya 30.8 CCL2 IL1B IL6 TNF
41 pyoderma gangrenosum 30.8 CXCL8 PSTPIP1 TNF
42 pyoderma 30.7 CXCL8 MMP1 PSTPIP1 TNF
43 autoimmune disease 30.7 CCL2 IL17A IL1B IL6 LTA PTPN22
44 bone resorption disease 30.7 IL6 TNFRSF11A TNFSF11
45 colitis 30.6 CXCL8 IL17A IL1B IL6 LACC1 TNF
46 anterior uveitis 30.6 IL6 PTPN22 TNF
47 endocarditis 30.6 CXCL8 IL6 TNF
48 diabetes mellitus 30.6 IL1A IL1B IL6 LTA PTPN22 TNF
49 bronchiolitis 30.5 CXCL8 IL17A IL6 TNF
50 fasciitis 30.4 CXCL8 IL6 TNF

Graphical network of the top 20 diseases related to Arthritis:



Diseases related to Arthritis
Sources

Symptoms & Phenotypes for Arthritis

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UMLS symptoms related to Arthritis:


joint stiffness, arthralgia, back pain, sciatica, muscle cramp, metatarsalgia

GenomeRNAi Phenotypes related to Arthritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression GR00224-A-2 8.8 IL1A MMP13 MMP9

MGI Mouse Phenotypes related to Arthritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.27 IL17A IL1A IL1B IL6 LACC1 LTA
2 hematopoietic system MP:0005397 10.25 IL17A IL1A IL1B IL6 LACC1 LTA
3 immune system MP:0005387 10.25 CCL2 IL17A IL1A IL1B IL6 LACC1
4 integument MP:0010771 9.86 IL1A IL1B IL6 MMP13 MMP9 TNF
5 neoplasm MP:0002006 9.81 IL1A IL1B IL6 MIF MMP1 MMP9
6 respiratory system MP:0005388 9.61 IL17A IL6 LTA MMP9 PTPN22 TNF
7 skeleton MP:0005390 9.32 IL17A IL1B IL6 LTA MMP13 MMP3
Sources

Drugs & Therapeutics for Arthritis

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FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Rayos 18 PREDNISONE Horizon Pharma July of 2012

Drugs for Arthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1061)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-05-2, 1959-05-2 126941
2
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-05-9 6006 143
3
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75706-12-6 3899
4
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 185243-69-0
5
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
6
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 332348-12-6 10237
7
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 174722-31-7 10201696
8
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
9
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83-43-2 6741
10
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 2921-57-5
11
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 302-25-0
12
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 16590-41-3 5360515
13
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
14
Hydroxychloroquine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 118-42-3 3652
15
Sulfasalazine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 599-79-1 5353980 5359476
16
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 104987-11-3 445643 439492
17
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 15307-86-5 3033
18
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 202409-33-4 123619
19
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
20
Entecavir Approved, Investigational Phase 4,Phase 3,Not Applicable 142217-69-4 153941
21
Cimetidine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 51481-61-9 2756
22
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
23
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 1177-87-3
24
Glucosamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 3416-24-8 439213
25
Spironolactone Approved Phase 4,Phase 2 52-01-7, 1952-01-7 5833
26
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
27
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22204-53-1 1302 156391
28
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 169590-42-5 2662
29
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 9004-61-9 53477741
30
Dimethyl fumarate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 624-49-7 637568 5271565
31
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7440-66-6
32
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
33
Polidocanol Approved Phase 4 9002-92-0
34
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
35
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 53-03-2 5865
36
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
37
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
38
Heparin Approved, Investigational Phase 4,Phase 3,Not Applicable 9005-49-6 772 46507594
39
Thrombin Approved, Investigational Phase 4,Phase 1
40
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
41
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
42
Dalteparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6
43
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
44
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
45
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 378-44-9 9782
46
Ketorolac Approved Phase 4,Phase 3,Phase 2,Not Applicable 66635-83-4, 74103-06-3 3826
47
Iron Approved Phase 4,Phase 1,Phase 2,Not Applicable 7439-89-6 23925
48
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Not Applicable 366789-02-8
49
Chitosan Approved Phase 4,Not Applicable 9012-76-4 71853
50
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 175805 71273

Interventional clinical trials:

(show top 50) (show all 7552)
# Name Status NCT ID Phase Drugs
1 Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis Unknown status NCT02087696 Phase 4 Tocilizumab
2 Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic Arthritis Unknown status NCT01939132 Phase 4 Open label H.P. Acthar Gel
3 Efficacy Study of Leflunomide to Treat Juvenile Idiopathic Arthritis Unknown status NCT02024334 Phase 4 Leflunomide
4 Etanercept and Methotrexate in Patients to Induce Remission in Early Arthritis (EMPIRE) Unknown status NCT01303874 Phase 4 Etanercept (ETN);Placebo
5 Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis Unknown status NCT01000441 Phase 4 infliximab, etanercept, adalimumab;abatacept, rituximab or tocilizumab
6 Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis Unknown status NCT00291915 Phase 4 Adalimumab;Methotrexate
7 Effectiveness of Iguratimod Versus Placebo to Treat Early Rheumatoid Arthritis on MRI Unknown status NCT01893151 Phase 4 Iguratimod;Iguratimod placebo
8 Long-term Efficacy of Iguratimod Alone or Iguratimod in Combination With Methotrexate in Patients With Rheumatoid Arthritis Unknown status NCT01548001 Phase 4 Iguratimod;Methotrexate
9 Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis Unknown status NCT01301703 Phase 4
10 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
11 Inhibition of Co-Stimulation in Rheumatoid Arthritis Unknown status NCT02652273 Phase 4 Abatacept
12 Withdrawal of Etanercept After Successful Treatment of Juvenile Idiopathic Arthritis Unknown status NCT01287715 Phase 4 etanercept;etanercept
13 Study of Iguratimod Plus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheumatoid Arthritis Unknown status NCT02275299 Phase 4 Iguratimod;Leflunomide;Methotrexate
14 TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis Unknown status NCT00908089 Phase 4 Trexan+Salazopyrin+Oxiklorin+prednisolone + infliximab;Trexan+Salazopyrin+Oxiklorin+prednisolone + placebo
15 Remission Induction in Very Early Rheumatoid Arthritis Unknown status NCT00523692 Phase 4 Etanercept, methotrexate and depomedrone;depemedrone
16 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
17 Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis Unknown status NCT01002716 Phase 4
18 The Clinical Efficacy and Safety of Tacrolimus in Refractory Rheumatoid Arthritis Patients for 6 Months Treatment Unknown status NCT02837978 Phase 4 Tacrolimus;MTX
19 REstore Working Ability in RheumatoiD Arthritis Unknown status NCT01405326 Phase 4
20 Comparison of the Effect of Etoricoxib and Diclofenac on Early Morning Activity in Rheumatoid Arthritis (RA) Unknown status NCT01067430 Phase 4 Etoricoxib;Diclofenac
21 Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker Unknown status NCT01072058 Phase 4 TNF blockers (infliximab, adalimumab, etanercept)
22 Rheumatoid Arthritis Patients in Training Unknown status NCT00434200 Phase 4
23 Evaluation Effects of Treatment With IL-6R Inhibitor on Clinical Response and Biomarkers in Patients With Rheumatoid Arthritis (RA) Not Responding to DMARDs and/or a First Biological Agent. Unknown status NCT01835613 Phase 4
24 Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Unknown status NCT02132234 Phase 4 Etanercept;Adalimumab;Certolizumab;Infliximab
25 Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis Unknown status NCT00216177 Phase 4 Infliximab;Adalimumab
26 Ultrasonographic Monitoring of Response to Infliximab in Patients With Rheumatoid Arthritis Unknown status NCT01282528 Phase 4
27 Effect of Tocilizumab to the Cellular Immune Response to Influenza Vaccine Unknown status NCT01980836 Phase 4
28 Entecavir for Biological Agents Associated HBV Reactivation in Inflammatory Arthritis Patients Unknown status NCT01907230 Phase 4 Entecavir
29 Bucillamine Study of Holding Remission After Infliximab Dose-off Unknown status NCT00716248 Phase 4 bucillamine;methotrexate
30 Very Early Versus Delayed Etanercept in Patients With RA Unknown status NCT02433184 Phase 4 Etanercept;Methotrexate;Sulfasalazine;Hydroxychloroquine;Etanercept;Methotrexate
31 Efficacy and Safety of Adalimumab 80 mg Every Other Week With Methotrexate Unknown status NCT01270035 Phase 4 Adalimumab
32 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
33 Gait Analysis of Ankle Arthroplasty and Arthrodesis Unknown status NCT00921076 Phase 4
34 Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis Unknown status NCT01223976 Phase 4
35 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
36 Corticosteroids as Additive in Temporomandibular Joint (TMJ) Arthrocentesis Unknown status NCT01275014 Phase 4 Dexamethasone;Isotonic saline
37 The Long-term Evaluation of Glucosamine Sulphate Study Unknown status NCT00513422 Phase 4
38 The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy Unknown status NCT02539069 Phase 4
39 The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) Unknown status NCT02539056 Phase 4
40 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4 spironolactone
41 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
42 Acthar for the Treatment of Systemic Lupus Erythematosus in Patients With a History of Persistently Active Disease Unknown status NCT01753401 Phase 4 Acthar;Placebo for Acthar
43 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4 Imrecoxib
44 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4 Guli capsule;Kangguzengsheng capsule
45 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
46 Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection Unknown status NCT02539095 Phase 4
47 Comparison of Efficacy and Safety of Microfracture and Modified Microfracture Unknown status NCT02539030 Phase 4
48 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
49 The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Unknown status NCT00422643 Phase 4 Sodium hyaluronate (hyaluronic acid)
50 The Influence of Adalimumab on Cardiovascular and Metabolic Risk in Psoriasis Unknown status NCT01088165 Phase 4 Adalimumab treatment arm;Fumaric acid esters treatment group

Search NIH Clinical Center for Arthritis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Arthritis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Arthritis:
AlloStem�, adipose-derived mesenchymal stem cells combined with allograft bone for bone grafting
Embryonic/Adult Cultured Cells Related to Arthritis:
Adipose-derived mesenchymal stem cells combined with allograft bone (AlloStem�) PMIDs: 22500696

Cochrane evidence based reviews: arthritis

Sources

Genetic Tests for Arthritis

About this section

Genetic tests related to Arthritis:

# Genetic test Affiliating Genes
1 Arthritis 29
Sources

Anatomical Context for Arthritis

About this section

MalaCards organs/tissues related to Arthritis:

41
Bone, T Cells, Lung, Testes, Endothelial, Neutrophil, B Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Arthritis:

19
Joint, Skin Over The Joint
Sources

Publications for Arthritis

About this section

Articles related to Arthritis:

(show top 50) (show all 22916)
# Title Authors Year
1
Helminth-based therapies for rheumatoid arthritis: A systematic review and meta-analysis. ( 30529501 )
2019
2
Do neuronal microvascular activation and resultant dysfunction in rheumatoid arthritis contribute to chronic pain? ( 30531079 )
2019
3
A successful treatment of rheumatoid arthritis-related interstitial pneumonia with nintedanib. ( 30533376 )
2019
4
Histone Protein Epitope Mapping for Autoantibody Recognition in Rheumatoid Arthritis. ( 30539581 )
2019
5
Amelioration of clinical symptoms of patients with refractory rheumatoid arthritis following treatment with autologous bone marrow-derived mesenchymal stem cells: A successful clinical trial in Iran. ( 30551438 )
2019
6
Sodium Chloride Aggravates Arthritis via Th17 Polarization. ( 30554495 )
2019
7
Effects of Structured Exercise Training in Children and Adolescents With Juvenile Idiopathic Arthritis. ( 30557274 )
2019
8
Commentary on "Effects of Structured Exercise Training in Individuals With Juvenile Idiopathic Arthritis". ( 30557275 )
2019
9
Centromere Protein-F-like Pattern in a Patient With Rheumatoid Arthritis. ( 30430789 )
2019
10
Tofacitinib for psoriatic arthritis (PsA) is now approved by the European Commission. ( 30380114 )
2019
11
Self-rated walking disability and dynamic ankle joint stiffness in children and adolescents with Juvenile Idiopathic Arthritis receiving intraarticular corticosteroid joint injections of the foot. ( 30396058 )
2019
12
Expression of human and Porphyromonas gingivalis glutaminyl cyclases in periodontitis and rheumatoid arthritis-A pilot study. ( 30399509 )
2019
13
Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-α level in Freund's complete adjuvant-induced arthritis in rats. ( 30336303 )
2019
14
Rheumatoid arthritis - a mathematical model. ( 30347191 )
2019
15
Targeting the extracellular matrix for delivery of bioactive molecules to sites of arthritis. ( 30311636 )
2019
16
Is arthritis associated with suicidal ideation and quality of life? ( 30270646 )
2019
17
The prevalence of depression and insomnia symptoms among patients with rheumatoid arthritis and osteoarthritis in Poland: a case control study. ( 30286609 )
2019
18
Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis. ( 29070531 )
2018
19
miR-522 Modulated the Expression of Proinflammatory Cytokines and Matrix Metalloproteinases Partly via Targeting Suppressor of Cytokine Signaling 3 in Rheumatoid Arthritis Synovial Fibroblasts. ( 29394098 )
2018
20
Discitis caused by rat bite fever in a rheumatoid arthritis patient on tocilizumab-first ever case. ( 29522179 )
2018
21
"STATus of STAT3 in Psoriatic Arthritis." ( 29439293 )
2018
22
The DNA methylation landscape of CD4<sup>+</sup>T cells in oligoarticular juvenile idiopathic arthritis. ( 28969936 )
2018
23
The association between caspase-5 gene polymorphisms and rheumatoid arthritis in a Chinese population. ( 29158166 )
2018
24
Association of heterogeneity of the thyroid gland with matrix metalloproteinase-3 in rheumatoid arthritis patients with Hashimoto's thyroiditis. ( 29442475 )
2018
25
Bacteremia and Septic Arthritis due to a Nontoxigenic Strain of<i>Clostridium difficile</i>in a Patient With Sickle Cell Disease. ( 29410974 )
2018
26
Usefulness of tocilizumab for treating rheumatoid arthritis with myelodysplastic syndrome: A case report and literature review. ( 29924032 )
2018
27
HMGB proteins and arthritis. ( 28916968 )
2018
28
Minimal Disease Activity among Active Psoriatic Arthritis Patients Treated with Secukinumab: 2-year Results from the FUTURE 2 Study. ( 29409133 )
2018
29
Rituximab therapy in rheumatoid arthritis and primary biliary cholangitis. ( 29338925 )
2018
30
Effect of Biologics on Fatigue in Psoriatic Arthritis: A Systematic Literature Review with Meta-analysis. ( 29452303 )
2018
31
Simultaneous Quadruple Joint Replacement (QJR) in Disabling Juvenile Rheumatoid Arthritis - a Case Report with Review of Literature. ( 29911143 )
2018
32
Chronic reactive arthritis associated with prostatitis caused by<i>Neisseria meningitidis</i>. ( 29374652 )
2018
33
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report. ( 29891129 )
2018
34
Causal association between rheumatoid arthritis and aA decreased risk of Alzheimer's disease : AA Mendelian randomization study. ( 29974225 )
2018
35
Involvement of M1/M2 macrophages in the pathomechanisms of intralymphatic histiocytosis associated with rheumatoid arthritis. ( 29905385 )
2018
36
Cost and Cost Effectiveness of Treatments for Psoriatic Arthritis: A Systematic Literature Review. ( 29441473 )
2018
37
Treatment Patterns Among Patients with Psoriatic Arthritis Treated with a Biologic in the United States: Descriptive Analyses from an Administrative Claims Database. ( 29952704 )
2018
38
Clinical, Imaging, and Pathological Suppression of Synovitis in Rheumatoid Arthritis: Is the Disease Curable? ( 29868592 )
2018
39
Burden of Depression among Working-Age Adults with Rheumatoid Arthritis. ( 29971163 )
2018
40
Enthesitis: A hallmark of psoriatic arthritis. ( 29429762 )
2018
41
Primary meningococcal arthritis as a presentation of nodal marginal zone lymphoma. ( 29367362 )
2018
42
Tetraspanin CD82 affects migration, attachment and invasion of rheumatoid arthritis synovial fibroblasts. ( 29980577 )
2018
43
Use of biological disease modifying antirheumatic drugs in rheumatoid arthritis in Austria from 2008 to 2011 : AA retrospective analysis of 72% of the population. ( 29445863 )
2018
44
A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients. ( 29973208 )
2018
45
Acute septic arthritis of the knee: A rare case report of infection with Parvimonas micra after an intra-articular corticosteroid injection for osteoarthritis. ( 29305995 )
2018
46
Physical Activity Assessment Using an Activity Tracker in Patients with Rheumatoid Arthritis and Axial Spondyloarthritis: Prospective Observational Study. ( 29295810 )
2018
47
Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab. ( 29485546 )
2018
48
High Adherence Observed to System-Level Performance Measures for Rheumatoid Arthritis in a National Early Arthritis Cohort Over 8 Years. ( 29450976 )
2018
49
Pain threshold and temporomandibular function in systemic sclerosis: comparison with psoriatic arthritis. ( 29445986 )
2018
50
Lipoma Arborescens Associated With Psoriatic Arthritis in an Adolescent Boy: A Case Report and Review of the Literature. ( 29933323 )
2018