Aliases & Classifications for Arthritis

MalaCards integrated aliases for Arthritis:

Name: Arthritis 12 74 29 54 6 42 3 43 15 37 17 71
Inflammatory Joint Disease 54 71
Inflammatory Disorder of Joint 12


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Disease Ontology 12 DOID:848
MeSH 43 D001168
NCIt 49 C2883
SNOMED-CT 67 3723001
UMLS 71 C0003864 C0683381

Summaries for Arthritis

MedlinePlus : 42 If you feel pain and stiffness in your body or have trouble moving around, you might have arthritis. Most kinds of arthritis cause pain and swelling in your joints. Joints are places where two bones meet, such as your elbow or knee. Over time, a swollen joint can become severely damaged. Some kinds of arthritis can also cause problems in your organs, such as your eyes or skin. Types of arthritis include Osteoarthritis is the most common type of arthritis. It's often related to aging or to an injury. Autoimmune arthritis happens when your body's immune system attacks healthy cells in your body by mistake. Rheumatoid arthritis is the most common form of this kind of arthritis. Juvenile arthritis is a type of arthritis that happens in children. Infectious arthritis is an infection that has spread from another part of the body to the joint. Psoriatic arthritis affects people with psoriasis. Gout is a painful type of arthritis that happens when too much uric acid builds up in the body. It often starts in the big toe. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

MalaCards based summary : Arthritis, also known as inflammatory joint disease, is related to juvenile rheumatoid arthritis and rheumatoid arthritis, and has symptoms including joint stiffness, arthralgia and back pain. An important gene associated with Arthritis is RELN (Reelin), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Betamethasone and Nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include joint, skin over the joint and bone, and related phenotypes are Increased vaccinia virus (VACV) infection and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : 12 A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located in joint and/or redness located in skin over the joint.

CDC : 3 Arthritis means inflammation or swelling of one or more joints. It describes more than 100 conditions that affect the joints, tissues around the joint, and other connective tissues. Specific symptoms vary depending on the type of arthritis, but usually include joint pain and stiffness.

Wikipedia : 74 Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include... more...

Related Diseases for Arthritis

Diseases in the Arthritis family:

Transient Arthritis

Diseases related to Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2462)
# Related Disease Score Top Affiliating Genes
1 juvenile rheumatoid arthritis 36.1 TNF MMP3 MIF LTA IL6 IL1B
2 rheumatoid arthritis 36.1 TNFSF11 TNF PTPN22 MMP9 MMP3 MMP13
3 psoriatic arthritis 35.9 TNFSF11 TNF PTPN22 NOD2 MMP3 MMP1
4 reactive arthritis 35.6 TNF IL6 IL1B IL17A IL10
5 rheumatoid arthritis, systemic juvenile 35.5 MIF LACC1 IL6
6 systemic onset juvenile idiopathic arthritis 35.3 TNF IL1B
7 psoriatic juvenile idiopathic arthritis 35.3 PSTPIP1 NOD2
8 oligoarticular juvenile idiopathic arthritis 35.1 TNF PTPN22 MIF
9 spondyloarthropathy 1 34.9 TNFSF11 TNF NOD2 MMP3 IL17A
10 osteoarthritis 34.9 TNFSF11 TNF MMP9 MMP3 MMP13 MMP1
11 blau syndrome 34.8 TNF PSTPIP1 NOD2 IL1B IL10
12 psoriasis 34.2 TNF PTPN22 NOD2 LTA IL6 IL1B
13 adult-onset still's disease 34.1 TNF MIF IL6 IL1B
14 systemic lupus erythematosus 34.0 TNF PTPN22 MMP9 MIF LTA IL6
15 lyme disease 34.0 TNF MMP9 IL6 IL1B IL17A
16 behcet syndrome 33.9 TNF PTPN22 PSTPIP1 NOD2 LTA IL6
17 palindromic rheumatism 33.8 TNF PTPN22 IL1B
18 arthropathy 33.8 TNFSF11 TNF MMP3 MMP13 MMP1 LTA
19 rheumatic disease 33.8 TNF MMP3 IL1B IL10
20 fibromyalgia 33.7 TNF IL6 IL1B IL10 CCL2
21 osteoporosis 33.7 TNFSF11 TNF MMP9 MMP3 MIF IL6
22 familial mediterranean fever 33.7 TNF PSTPIP1 NOD2 IL6 IL1B IL17A
23 interstitial lung disease 33.7 TNF MMP9 IL6 IL1B IL1A IL17A
24 connective tissue disease 33.7 TNFSF11 TNF MMP3 MMP13 IL6 IL1B
25 crohn's disease 33.6 TNF PTPN22 NOD2 LACC1 IL6 IL1B
26 carpal tunnel syndrome 33.5 IL6 IL1B CCL2
27 temporal arteritis 33.5 TNF PTPN22 IL6 IL17A CCL2
28 shigellosis 33.5 TNF LTA IL1B IL10
29 dermatitis 33.5 TNF NOD2 IL6 IL1A IL17A IL10
30 sarcoidosis 1 33.5 TNF NOD2 MIF LTA IL1B IL1A
31 bone disease 33.5 TNFSF11 TNF MMP9 MMP13 LTA IL6
32 mixed connective tissue disease 33.5 TNF IL6 IL10
33 bronchiolitis obliterans 33.5 TNF MMP9 IL6 IL17A IL10
34 dermatitis, atopic 33.5 TNF NOD2 MIF LTA IL6 IL1B
35 cartilage disease 33.4 TNF MMP3 MMP13
36 spinal stenosis 33.4 MMP3 MMP13 MMP1
37 neurofibromatosis, type ii 33.4 TNF PSTPIP1 IL6 IL1A
38 osteonecrosis 33.4 TNFSF11 TNF IL10
39 brucellosis 33.4 TNF IL6 IL17A IL10
40 scleritis 33.3 TNF MMP9 CCL2
41 rosacea 33.3 TNF MMP9 MMP3 IL6
42 tropical spastic paraparesis 33.3 MMP9 IL6 IL17A IL10
43 autoimmune disease 33.3 TNF PTPN22 MMP9 MIF LTA IL6
44 rheumatoid nodulosis 33.3 MMP9 MMP3
45 cinca syndrome 33.3 PSTPIP1 NOD2 IL6 IL1B
46 common variable immunodeficiency 33.1 TNF NOD2 IL6 IL10
47 spondylitis 33.0 TNFSF11 TNF NOD2 LTA IL6 IL17A
48 scoliosis 33.0 TNFSF11 RELN MMP9 MMP3 MMP13 IL6
49 synovitis 32.9 TNFSF11 TNF RELN MMP9 MMP3 MMP13
50 uveitis 32.8 TNF NOD2 LTA IL6 IL1A IL17A