Aliases & Classifications for Arthritis, Sacroiliac

MalaCards integrated aliases for Arthritis, Sacroiliac:

Name: Arthritis, Sacroiliac 56
Sacroiliac Arthritis 6

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
arthritis, sacroiliac:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 108100
MedGen 41 C0748473

Summaries for Arthritis, Sacroiliac

MalaCards based summary : Arthritis, Sacroiliac, also known as sacroiliac arthritis, is related to arthritis and sarcoidosis 1. An important gene associated with Arthritis, Sacroiliac is RELN (Reelin). The drugs Methylprednisolone and Methylprednisolone hemisuccinate have been mentioned in the context of this disorder. Affiliated tissues include bone, and related phenotypes are paresthesia and pruritus

More information from OMIM: 108100

Related Diseases for Arthritis, Sacroiliac

Diseases related to Arthritis, Sacroiliac via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 arthritis 10.2
2 sarcoidosis 1 10.1
3 osteomyelitis 10.1
4 endocarditis 10.1
5 brucellosis 10.1
6 systemic lupus erythematosus 9.9
7 rheumatoid arthritis 9.9
8 late congenital syphilis 9.9
9 inflammatory spondylopathy 9.9
10 toxic shock syndrome 9.9
11 ankylosis 9.9
12 syphilis 9.9
13 spondylitis 9.9
14 lupus erythematosus 9.9
15 congenital syphilis 9.9
16 back pain 9.9

Graphical network of the top 20 diseases related to Arthritis, Sacroiliac:



Diseases related to Arthritis, Sacroiliac

Symptoms & Phenotypes for Arthritis, Sacroiliac

Human phenotypes related to Arthritis, Sacroiliac:

31
# Description HPO Frequency HPO Source Accession
1 paresthesia 31 very rare (1%) HP:0003401
2 pruritus 31 HP:0000989
3 sacroiliac arthritis 31 HP:0012317

Symptoms via clinical synopsis from OMIM:

56
Genitourinary Kidneys:
renal disease, uncharacterized (in some patients)

Skeletal Hands:
swelling (in some patients)
tingling (in some patients)
itching ( in some patients)

Laboratory Abnormalities:
elevated uric acid on urinalysis (in some patients)

Skeletal Pelvis:
sacroiliac pain, intermittent, severe

Skeletal Feet:
swelling (in some patients)
tingling (in some patients)
itching ( in some patients)

Clinical features from OMIM:

108100

Drugs & Therapeutics for Arthritis, Sacroiliac

Drugs for Arthritis, Sacroiliac (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
2
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3 2921-57-5
3
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
4 Prednisolone acetate Approved, Vet_approved Phase 2, Phase 3 52-21-1
5
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3 302-25-0
6
Prednisolone hemisuccinate Experimental Phase 2, Phase 3 2920-86-7
7 Antiemetics Phase 2, Phase 3
8 Anti-Inflammatory Agents Phase 2, Phase 3
9 Gastrointestinal Agents Phase 2, Phase 3
10 Neuroprotective Agents Phase 2, Phase 3
11 Protective Agents Phase 2, Phase 3
12 glucocorticoids Phase 2, Phase 3
13 Methylprednisolone Acetate Phase 2, Phase 3
14 Antineoplastic Agents, Hormonal Phase 2, Phase 3
15 Autonomic Agents Phase 2, Phase 3
16 Hormone Antagonists Phase 2, Phase 3
17 Hormones Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison Between Intra-articular Pulsed Radiofrequency With Steroids Injection Versus Intra-articular Steroids Injection in Chronic Sacroiliac Joint Arthritis Recruiting NCT03564106 Phase 2, Phase 3 intraarticular radiofrequency + intraarticular methylprednisolone;intraarticular methylprednisolone

Search NIH Clinical Center for Arthritis, Sacroiliac

Genetic Tests for Arthritis, Sacroiliac

Anatomical Context for Arthritis, Sacroiliac

MalaCards organs/tissues related to Arthritis, Sacroiliac:

40
Bone

Publications for Arthritis, Sacroiliac

Articles related to Arthritis, Sacroiliac:

(show all 44)
# Title Authors PMID Year
1
Sacroiliac pain and CT-guided steroid injection treatment: high-grade arthritis has an adverse effect on outcomes in long-term follow-up. 61
26241533 2015
2
[Analysis of clinical and imaging characteristics of infectious sacroiliac arthritis and review of literatures]. 61
26080821 2015
3
Ultrasound-guided versus fluoroscopy-guided sacroiliac joint intra-articular injections in the noninflammatory sacroiliac joint dysfunction: a prospective, randomized, single-blinded study. 61
24121083 2014
4
Lumbar disc degenerative disease: disc degeneration symptoms and magnetic resonance image findings. 61
24353850 2013
5
Outcome of distraction interference arthrodesis of the sacroiliac joint for sacroiliac arthritis. 61
24133301 2013
6
Juvenile Psoriatic Arthritis (JPsA): juvenile arthritis with psoriasis? 61
23497068 2013
7
2 cases of HLA-B27-positive seronegative spondylarthritides in pediatric age treated with adalimumab. 61
24390108 2013
8
Distribution of HLA-B27 and CYP2D6*4 mutations in the middle Black Sea area (Tokat) of Turkey. 61
22180068 2011
9
Pyogenic Sacroiliac Arthritis Resulting in Septic Shock in a Postpartum Patient: A Rare Problem with a Rare Organism: A Case Report. 61
29252253 2011
10
[Chlamydia-associated arthritis and enteropathic arthritis--two important spondyloarthritides]. 61
21720100 2011
11
Long-term results of iliac wing fixation below extensive fusions in ambulatory adult patients with spinal disorders. 61
20124910 2010
12
Sacroiliac joint involvement in psoriasis. 61
20354857 2010
13
Possible use of arthrodesis for intractable sacroiliitis in spondylarthropathy: report of two cases. 61
11598524 2001
14
[Abscess of the psoas muscle: analysis of 11 cases and review of the literature]. 61
9542304 1998
15
[Reiter's syndrome--analysis of 187 patients]. 61
9471825 1997
16
[Septic sacroiliac arthritis in an adolescent]. 61
9230990 1997
17
Acute sacroiliac arthritis and sarcoidosis. 61
9178403 1997
18
[A case with systemic lupus erythematosus complicated with tuberculosis sacroiliac arthritis]. 61
9128422 1997
19
Infective sacroiliac arthritis and psoas abscess caused by Streptococcus milleri. 61
2778345 1989
20
[Pyogenic sacroiliac arthritis in children. Apropos of 6 cases]. 61
3065722 1988
21
[Relation between sacroiliac arthritis in Reiter's syndrome and the HLA-B27 antigen]. 61
3877964 1985
22
CT scanning in septic sacroiliac arthritis or periarticular osteomyelitis. 61
6734163 1984
23
[Acute pyogenic sacroiliac arthritis in children]. 61
6316511 1983
24
[Acute pyogenic sacroiliac arthritis in the child]. 61
6402973 1983
25
[Pyogenic sacroiliac arthritis in children. Analysis and commentary apropos of 7 cases]. 61
6850970 1983
26
Computed tomography in the evaluation of sacroiliac arthritis. 61
7220889 1981
27
[Deep bone biopsy using a trocar under television radioscopy in sacroiliac arthritis]. 61
7221434 1981
28
Aseptic arthritis after gonorrhoea. 61
6770765 1980
29
[Early sacroiliac arthritis without clinical symptoms]. 61
451376 1979
30
[Sacroiliac arthritis in sarcoidosis]. 61
749187 1978
31
[Diagnosis and treatment of sacroiliac arthritis]. 61
982068 1976
32
Displaced fractures of the major pelvis: a method of management. 61
1192635 1975
33
[Sacroiliac arthritis revealing an enterococcal endocarditis]. 61
4688237 1973
34
[Postabortum sacroiliac arthritis]. 61
5153226 1971
35
[Apropos of a case of sacroiliac arthritis of melitococcal origin]. 61
13707614 1960
36
SACROILIAC arthritis. 61
13857545 1959
37
[Sacroiliac arthritis in ankylosing spondylarthritis]. 61
13290509 1955
38
[A case of sacroiliac arthritis caused by late congenital syphilis]. 61
12976090 1952
39
[Chronic non-tuberculous sacroiliac arthritis of young adults]. 61
14798197 1950
40
[Sacroiliac arthritis in the group of isolated lumbosacralgias]. 61
14798198 1950
41
[Three exceptional varieties of sacroiliac arthritis and arthroses]. 61
14798199 1950
42
[A case of metastatic sacroiliac arthritis during bacterial endocarditis]. 61
14786620 1950
43
[Non tuberculous sacroiliac arthritis]. 61
15396891 1949
44
Brucellosis as a cause of sacroiliac arthritis; a study of its relationship to rheumatoid spondylitis. 61
18877477 1948

Variations for Arthritis, Sacroiliac

ClinVar genetic disease variations for Arthritis, Sacroiliac:

6 ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 RELN NC_000007.14:g.103523425T>Cundetermined variant Pathogenic 684430 7:103163872-103163872

Expression for Arthritis, Sacroiliac

Search GEO for disease gene expression data for Arthritis, Sacroiliac.

Pathways for Arthritis, Sacroiliac

GO Terms for Arthritis, Sacroiliac

Sources for Arthritis, Sacroiliac

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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