Arthrogryposis, Distal, Type 6 disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Arthrogryposis, Distal, Type 6

MalaCards integrated aliases for Arthrogryposis, Distal, Type 6:

Name: Arthrogryposis, Distal, Type 6 ⁵⁸

Arthrogryposis-Like Hand Anomaly-Sensorineural Deafness Syndrome ⁶⁰

Arthrogryposis and Sensorineural Deafness ⁵⁸

Distal Arthrogryposis Type 6 ⁶⁰

Da6 ⁵⁸

Characteristics:

Orphanet epidemiological data:

⁶⁰

arthrogryposis-like hand anomaly-sensorineural deafness syndrome
Prevalence: <1/1000000 (Worldwide); Age of onset: Neonatal; Age of death: normal life expectancy;

OMIM:

⁵⁸

Inheritance:
autosomal dominant

HPO:

³³

arthrogryposis, distal, type 6:
Inheritance autosomal dominant inheritance

Classifications:

MalaCards categories:
Global: Fetal diseases Rare diseases Genetic diseases
Anatomical: Ear diseases Neuronal diseases Respiratory diseases Bone diseases Oral diseases Muscle diseases Eye diseases Smell/Taste diseases

See all MalaCards categories (disease lists)

ICD10: ³⁵

Congenital malformations, deformations and chromosomal abnormalities

Congenital malformations and deformations of the musculoskeletal system

Other congenital musculoskeletal deformities

Other specified congenital musculoskeletal deformities

Orphanet: ⁶⁰

Rare otorhinolaryngological diseases

Developmental anomalies during embryogenesis

External Ids:

OMIM ⁵⁸ 108200

MESH via Orphanet ⁴⁶ C535386

ICD10 via Orphanet ³⁵ Q68.8

UMLS via Orphanet ⁷⁵ C1862471

Orphanet ⁶⁰ ORPHA1144

MedGen ⁴³ C1862471

SNOMED-CT via HPO ⁷⁰ 111246005 237836003 238108007 more

Sources

Summaries for Arthrogryposis, Distal, Type 6

OMIM : ⁵⁸ Distal arthrogryposis type 6 (DA6) is distinguished by the additional feature of sensorineural deafness (summary by Bamshad et al., 2009). For a phenotypic description and a discussion of genetic heterogeneity of distal arthrogryposis, see DA1 (108120). (108200)

MalaCards based summary : Arthrogryposis, Distal, Type 6, also known as arthrogryposis-like hand anomaly-sensorineural deafness syndrome, is related to arthrogryposis-like hand anomaly and sensorineural deafness. The drugs Buprenorphine and Ethanol have been mentioned in the context of this disorder. Related phenotypes are joint stiffness and sensorineural hearing impairment

Sources

Related Diseases for Arthrogryposis, Distal, Type 6

Diseases in the Distal Arthrogryposis family:

Arthrogryposis, Distal, Type 1a	Arthrogryposis, Distal, Type 5
Arthrogryposis, Distal, Type 6	Arthrogryposis, Distal, Type 3
Arthrogryposis, Distal, Type 9	Arthrogryposis, Distal, Type 2e
Arthrogryposis, Distal, Type 7	Arthrogryposis, Distal, Type 8
Arthrogryposis, Distal, Type 10	Arthrogryposis, Distal, Type 2a
Arthrogryposis, Distal, Type 4	Arthrogryposis, Distal, Type 1b
Arthrogryposis, Distal, Type 5d

Diseases related to Arthrogryposis, Distal, Type 6 via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	arthrogryposis-like hand anomaly and sensorineural deafness	11.3

Sources

Symptoms & Phenotypes for Arthrogryposis, Distal, Type 6

Human phenotypes related to Arthrogryposis, Distal, Type 6:

⁶⁰ ³³ (show all 7)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	joint stiffness ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0001387
2	sensorineural hearing impairment ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0000407
3	arachnodactyly ⁶⁰ ³³	hallmark (90%)	Very frequent (99-80%)	HP:0001166
4	short stature ⁶⁰ ³³	frequent (33%)	Frequent (79-30%)	HP:0004322
5	cachexia ⁶⁰ ³³	frequent (33%)	Frequent (79-30%)	HP:0004326
6	arthrogryposis multiplex congenita ³³			HP:0002804
7	arthrogryposis-like hand anomaly ³³			HP:0005612

Symptoms via clinical synopsis from OMIM:

⁵⁸

Ears:
sensorineural hearing loss

Limbs:
arthrogryposis-like hand anomaly

Clinical features from OMIM:

108200

Sources

Drugs & Therapeutics for Arthrogryposis, Distal, Type 6

Drugs for Arthrogryposis, Distal, Type 6 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Buprenorphine

Approved, Illicit, Investigational, Vet_approved

Phase 1

52485-79-7

40400 644073

Synonyms:

(-)-buprenorphine

(−)-buprenorphine

(-)-Buprenorphine

(5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-(methyloxy)-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol

(5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol

[5alpha,7alpha(S)]-17-(Cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol

17-Cyclopropylmethyl-4,5a-epoxy-7a-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol

17-cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol

17-Cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol

17-Cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl-6-methoxy-6,14-endo-ethanomorphinan-3-ol

17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol

17-Cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol

2-(N-Cyclopropylmethyl-4,5a-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6a-yl)-3,3-dimethyl-2-butanol

2-(N-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol

2-(N-Cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol

2-(N-Cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-7alpha-yl)-3,3-dimethyl-2-butanol

2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanol

2-(N-Cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanol

2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol

2-[3-Cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol

21-(Cyclopropyl-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-Cyclopropyl-7a-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-cyclopropyl-7alpha-(2-hydroxy-3,3-dimethyl-2-butyl)-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-Cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

21-Cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine

52485-79-7

53152-21-9 (hydrochloride)

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-,

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (alphaS,5alpha,7alpha)- (9CI)

6029-M

AC1L23NL

AC1L9B1M

AC1LD8IH

Buprel

Buprenex

Buprenophine

Buprenorfina

Buprenorfina [INN-Spanish]

buprenorphine

Buprenorphine

Buprenorphine (JAN/INN)

Buprenorphine [INN:BAN]

Buprenorphine grünenthal brand

Buprenorphine Hcl

Buprenorphine hydrochloride

Buprenorphinum

Buprenorphinum [INN-Latin]

Buprex

C08007

C29H41NO4

CHEBI:3216

CHEMBL1201894

CHEMBL47085

CID40400

CID441363

CID5311033

CID6321408

CID644073

D07132

DB00921

DEA No. 9064

EINECS 257-950-6

Essex brand OF buprenorphine hydrochloride

Grünenthal brand OF buprenorphine

Grünenthal brand OF buprenorphine hydrochloride

Hydrochloride, buprenorphine

Key brand OF buprenorphine hydrochloride

LS-67682

MolPort-004-285-844

PDSP2_000111

Prefin

Probuphine

Reckitt and colman brand 1 OF buprenorphine hydrochloride

Reckitt and colman brand 2 OF buprenorphine hydrochloride

Reckitt benckiser brand OF buprenorphine hydrochloride

Reckitt brand OF buprenorphine hydrochloride

RX 6029 m

RX 6029M

RX-6029-m

RX-6029-M

Schering plough brand OF buprenorphine hydrochloride

Schering-plough brand OF buprenorphine hydrochloride

Subutex

Temgesic

Temgésic

Temgesic (TN)

UNII-40D3SCR4GZ

2

Ethanol

Approved

Phase 1

64-17-5

702

Synonyms:

(C6-C9)Alkyl alcohol

[CH2Me(OH)]

[OEtH]

02483_FLUKA

02851_FLUKA

02853_FLUKA

02854_FLUKA

02855_FLUKA

02856_FLUKA

02856_SIAL

02857_FLUKA

02857_SIAL

02858_FLUKA

02858_SIAL

02860_FLUKA

02865_FLUKA

02865_SIAL

02870_FLUKA

02870_SIAL

02875_FLUKA

02877_FLUKA

02878_FLUKA

02882_FLUKA

02882_SIAL

02883_FLUKA

02884_FLUKA

02890_FLUKA

02890_SIAL

02891_FLUKA

02891_SIAL

100C.NPA

121182-78-3

187380_ALDRICH

187380_SIAL

1-Hydroxyethane

24102_RIEDEL

24102_SIAL

24103_RIEDEL

24103_SIAL

24105_RIEDEL

24105_SIAL

24106_RIEDEL

24106_SIAL

24194_RIEDEL

24194_SIAL

245119_ALDRICH

245119_SIAL

270741_ALDRICH

270741_SIAL

277649_ALDRICH

277649_SIAL

2858_SIGMA

29221_FLUKA

32205_RIEDEL

32205_SIAL

32221_RIEDEL

32221_SIAL

32294_RIEDEL

32294_SIAL

34870_SIAL

34963_RIEDEL

39278_FLUKA

40210_ALDRICH

40210_RIEDEL

41322_FLUKA

458600_ALDRICH

458600_SIAL

459828_ALDRICH

459828_SIAL

459836_ALDRICH

459836_SIAL

459844_SIAL

48075_SUPELCO

493511_SIAL

493538_ALDRICH

493538_SIAL

493546_ALDRICH

493546_SIAL

64-17-5

676829_SIAL

68475-56-9

71076-86-3

71329-38-9

8000-16-6

8024-45-1

absolute alcohol

Absolute alcohol

Absolute Alcohol

Absolute ethanol

Absolute Ethanol

Absolute ethyl alcohol

AC1L19TW

AC1Q31MM

Aethanol

Aethanol [German]

Aethylalkohol

AHD 2000

AI3-01706

Alcare hand degermer

Alcare Hand Degermer

alcohol

Alcohol

Alcohol (ethyl)

Alcohol (USP)

Alcohol [USP]

ALCOHOL 5% IN D5-W

Alcohol anhydrous

Alcohol Anhydrous

Alcohol dehydrated

Alcohol denatured

alcohol etilico

Alcohol etilico

Alcohol etílico

Alcohol, absolute

Alcohol, Absolute

Alcohol, anhydrous

Alcohol, dehydrated

Alcohol, Dehydrated

Alcohol, denatured

Alcohol, diluted

Alcohol, Diluted

Alcohol, ethyl

Alcohol, grain

Alcohol, Grain

Alcohols

Alcohols, C1-3

Alcohols, C30

Alcohols, C6-9

Alcool ethylique

Alcool Ethylique

Alcool éthylique

Alcool etilico

Alcool Etilico

Algrain

Alkohol

Alkohol [German]

Alkoholu etylowego

Alkoholu Etylowego

Aminoethanol

Anhydrol

Anhydrol PM 4085

Anhydrous alcohol

Anhydrous ethanol

Äthanol

Äthylalkohol

Beta-Aminoethanol

Beta-Aminoethyl Alcohol

Beta-Ethanolamine

Beta-Hydroxyethylamine

bmse000297

C00469

C2H5OH

C2H6O

Caswell No. 426

Caswell No. 430

CCRIS 945

CDA 19

CDA 19-200

CHEBI:16236

CHEMBL545

CID702

Colamine

Cologne spirit

Cologne Spirit

Cologne spirits

D000431

D00068

DB00898

Dehydrated alcohol

Dehydrated ethanol

Dehydrated Ethanol

Denatured alcohol

Denatured Alcohol

Denatured Alcohol Cd-10

Denatured Alcohol Cd-5

Denatured Alcohol Cd-5a

Denatured Alcohol Sd-1

Denatured Alcohol Sd-13a

Denatured Alcohol Sd-17

Denatured Alcohol Sd-23a

Denatured Alcohol Sd-28

Denatured Alcohol Sd-30

Denatured Alcohol Sd-39b

Denatured Alcohol Sd-39c

Denatured Alcohol Sd-3a

Denatured Alcohol Sd-40m

Denatured ethanol

Denatured Ethanol

Desinfektol el

Desinfektol EL

Diluted alcohol

Distilled spirits

E2385_SIGMA

E7023_ALDRICH

E7023_SIAL

E7148_ALDRICH

E7148_SIAL

E7517_SIGMA

EINECS 200-578-6

EINECS 270-649-4

Envision Conditioner Pdd 9020

EOH

EOX

Esumiru WK 88

ETA

etanol

Etanol

Etanolo

Etanolo [Italian]

ethanol

éthanol

Ethanol (9CI)

Ethanol [JAN]

Ethanol 200 proof

Ethanol 200 Proof

Ethanol Absolute

Ethanol Absolute Bp

Ethanol Anhydrous

Ethanol Extra Pure

Ethanol solution

Ethanol Vapor

Ethanol, Silent Spirit

Ethanol, undenatured

Ethanolum anhydricum

Ethicap

Ethyl alc

ethyl alcohol

Ethyl alcohol

Ethyl Alcohol

Ethyl Alcohol & Water, 10%

Ethyl Alcohol & Water, 20%

Ethyl Alcohol & Water, 30%

Ethyl Alcohol & Water, 40%

Ethyl Alcohol & Water, 5%

Ethyl Alcohol & Water, 50%

Ethyl Alcohol & Water, 60%

Ethyl Alcohol & Water, 70%

Ethyl Alcohol & Water, 80%

Ethyl Alcohol & Water, 95%

Ethyl Alcohol & Water, 96%

Ethyl alcohol anhydrous

Ethyl Alcohol Anhydrous

Ethyl alcohol in alcoholic beverages

Ethyl alcohol usp

Ethyl Alcohol, Anhydrous

Ethyl Alcohol, Denatured

Ethyl hydrate

Ethyl Hydrate

Ethyl hydroxide

Ethyl Hydroxide

Ethylalcohol

Ethylalcohol [Dutch]

Ethylol

Ethylolamine

Ethyloxy Group

EtOH

Etylowy alkohol

FEMA No. 2419

FEMA Number 2419

Fermentation alcohol

Glycinol

grain alcohol

Grain alcohol

Hinetoless

HSDB 531

HSDB 82

Hydroxyethane

HYDROXYETHYL GROUP

I14-12648

IMS 99

Infinity pure

Infinity Pure

Jaysol

Jaysol S

LS-1539

LTBB002977

Lux

Methylated spirit

Methylated Spirit Mineralised

Methylcarbinol

Molasses alcohol

MolPort-001-785-844

NCGC00091458-01

nchem.651-comp3c

nchembio.552-comp10

nchembio.94-comp20

NCI-C03134

NSC 85228

NSC85228

Oxydimethylene Group

potato Alcohol

Potato alcohol

Punctilious ethyl alcohol

Pyro

QMHAIh@

Reagent Alcohol

Ru-Tuss Expectorant

SDA 3A

SDA 40-2

SDM No. 37

Sekundasprit

Silent spirit

Spirit

Spirits of wine

Spirits OF wine

spiritus vini

Spiritus vini

Spirt

SY Fresh M

Synasol

Tecsol

Tecsol C

Thanol

Thiofaco M-50

Undenatured ethanol

UNII-3K9958V90M

USAF EK-1597

WLN: Q2

3

Naloxone

Approved, Vet_approved

Phase 1

465-65-6

5284596

Synonyms:

(-)-N-allyl-14-hydroxynordihydroxymorphinan-6-one

(−)-naloxone

(-)-Naloxone

(5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one

(5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one

12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro(4,5-bcd)furanone

12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5(6H)-one

17-Allyl-3,14-dihydroxy-4,5a-epoxymorphinan-6-one

17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one

17-Allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one

17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-one

17-Allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-one

17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one

17-Allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-one

1-N-Allyl-14-hydroxynordihydromorphinone

1-N-Allyl-7,8-dihydro-14-hydroxynormorphinone

3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one

357-08-4 (hydrochloride)

465-65-6

abello Brand OF naloxone hydrochloride

abello, Naloxone

BIDD:GT0110

Boots brand OF naloxone hydrochloride

BPBio1_000136

BRD-K67511046-003-03-7

Bristol myers squibb brand OF naloxone hydrochloride

Bristol-myers squibb brand OF naloxone hydrochloride

BRN 1089071

BSPBio_000122

C07252

CHEBI:7459

CHEMBL80

CID5284596

Curamed brand OF naloxone hydrochloride

Curamed, naloxon

D08249

DB01183

DBL Naloxone

DBL Naloxone (TN)

Dihydride, naloxone hydrochloride

EINECS 207-365-7

EN 1530 base

EN 1530 Base

endo Brand OF naloxone hydrochloride

HMS2090F20

HSDB 3279

Hydrobromide, naloxone

Hydrochloride dihydride, naloxone

Hydrochloride, naloxone

lamepro Brand OF naloxone hydrochloride

l-N-Allyl-14-hydroxynordihydromorphinone

l-N-Allyl-7,8-dihydro-14-hydroxynormorphinone

l-Naloxone

L-Naloxone

LS-187184

LS-92141

MolPort-002-536-640

Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy- (8CI)

Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)- (9CI)

MRZ 2593 BR

MRZ 2593BR

MRZ 2593-BR

N-Allyl-4,5alpha-epoxy-3,14-dihydroxy-6-morphinanon

n-Allylnoroxymorphone

N-Allylnoroxymorphone

N-Allyl-noroxymorphone

Nalone

Nalossone

Nalossone [Dcit]

Nalossone [DCIT]

Naloxon curamed

Naloxon ratiopharm

Naloxona

Naloxona [INN-Spanish]

naloxone

Naloxone

Naloxone (INN)

Naloxone [INN:BAN]

Naloxone abello

Naloxone HCl

Naloxone hydrobromide

Naloxone hydrochloride

Naloxone hydrochloride dihydride

Naloxone hydrochloride, (5 beta,9 alpha,13 alpha,14 alpha)-isomer

Naloxone, (5 beta,9 alpha,13 alpha,14 alpha)-isomer

Naloxonratiopharm

Naloxon-ratiopharm

Naloxonum

Naloxonum [INN-Latin]

Narcan

Narcanti

Narcon

NCGC00024674-02

NSC 70413

NSC70413

PDSP2_001520

Prestwick0_000111

Prestwick1_000111

Prestwick2_000111

Prestwick3_000111

Ratiopharm brand OF naloxone hydrochloride

SERB brand OF naloxone hydrochloride

SMP1_000205

SPBio_002061

STOCK1N-69923

UNII-36B82AMQ7N

United drug brand OF naloxone hydrochloride

4

Naltrexone

Approved, Investigational, Vet_approved

Phase 1

16590-41-3

5360515

Synonyms:

16590-41-3

16676-29-2

17-(Cyclopropylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan-6-one

17-(Cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one

17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one

17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one

3,14-dihydroxy-17-(cyclopropylmethyl)-4,5alpha-epoxymorphinan-6-one

Antaxone

BIDD:GT0405

BPBio1_000146

BRD-K88172511-310-03-8

Bristol myers squibb brand OF naltrexone hydrochloride

Bristol-myers squibb brand OF naltrexone hydrochloride

BRN 3596648

BSPBio_000132

C07253

CCRIS 3506

Celupan

CHEBI:121459

CHEBI:7465

CHEMBL142

CID5360515

D05113

DB00704

Depade

Du pont brand OF naltrexone hydrochloride

EINECS 240-649-9

EN-1639A

HMS2089O11

HS-0002

HSDB 6750

Hydrochloride, naltrexone

Lacer brand OF naltrexone hydrochloride

lamepro Brand OF naltrexone hydrochloride

LS-92094

MLS002153483

MolPort-004-920-221

MorViva

Nalorex

Naltrexon

Naltrexona

Naltrexona [INN-Spanish]

naltrexone

Naltrexone

naltrexone (ReVia)

Naltrexone (USAN/INN)

Naltrexone [Usan:Ban:Inn]

Naltrexone [USAN:BAN:INN]

Naltrexone [USAN:INN:BAN]

Naltrexone Hcl

Naltrexone hydrochloride

Naltrexonum

Naltrexonum [INN-Latin]

N-Cyclopropylmethyl-14-hydroxydihydromorphinone

N-Cyclopropylmethylnoroxymorphone

Nemexin

Orphan brand OF naltrexone hydrochloride

PDSP2_000847

Pharmazam brand OF naltrexone hydrochloride

Prestwick0_000116

Prestwick1_000116

Prestwick2_000116

Prestwick3_000116

PTI-555

ReVia

Schering plough brand OF naltrexone hydrochloride

Schering-plough brand OF naltrexone hydrochloride

SMP1_000206

SPBio_002071

Trexan

UM-792

UNII-5S6W795CQM

United drug brand OF naltrexone hydrochloride

Vivitrex

Vivitrol

Vivitrol (TN)

5

Cocaine

Approved, Illicit

Phase 1

50-36-2

446220 5760

Synonyms:

(−)-cocaine

(-)-Cocaine

(-)-Cocaine base

(1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate

(1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate

(R)-Cocaine

[1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, methyl ester

[1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester

[1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester

1-Cocaine

1i7z

1q72

2beta-Carbomethoxy-3beta-benzoxytropane

2-beta-Carbomethoxy-3-beta-benzoxytropane

2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester)

2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)

2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylic acid benzoic acid (ester)

2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylate benzoate (ester)

2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylic acid benzoic acid (ester)

2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylate benzoate (ester)

2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylic acid benzoic acid (ester)

2-methyl-3β-hydroxy-1αH,5αH-tropane-2β-carboxylate benzoate (ester)

3beta-Hydroxy-2beta-tropanecarboxylic acid methyl ester benzoate (ester)

3-Tropanylbenzoate-2-carboxylic acid methyl ester

50-36-2

53-21-4 (hydrochloride)

610089_ALDRICH

610089_FLUKA

AC-16037

AC1L1EK2

AC1L1L2T

AC1L3U2D

AC1L9JBL

AC-20208

Allococaine

Allopseudococaine

Badrock

Bazooka

b-Cocain

Benzoylethylecgonine

Benzoylmethylecgonine

Bernice

Bernice [Street Name]

Bernies

beta-Cocain

Beta-Cocain

Blast

Blizzard

Blow

Blow [Street Name]

Bouncing Powder

Bump

Burese

C" Carrie

C01416

C8912_SIGMA

Cabello

Candy

Carrie

Caviar

Cecil

Cecil [Street Name]

Charlie

CHEBI:27958

Chicken Scratch

Cholly

CID11779748

CID2826

CID446220

CID5760

COC

Coca

Cocain

Cocaina

cocaine

Cocaine

Cocaine (TN)

Cocaine (USP)

Cocaine [BAN]

Cocaine free base

Cocaine Free Base

Cocaine HCL

Cocaine hydrochloride

Cocaine solution

Cocaine-M

cocainum

Cocainum

Cocktail

Coke

Cola

Corine

CPD-9776

Crack

Crack cocaine

D00110

Dama blanca

Dama Blanca

DB00907

DEA No. 9041

Delcaine

Depsococaine

Dextrocaine

DivK1c_000975

d-Pseudococaine

D-pseudococaine

Dust

Ecgonine methyl ester benzoate

Ecgonine methyl ester benzoate solution

Ecgonine, methyl ester, benzoate (ester)

EINECS 200-032-7

Eritroxilina

Erytroxylin

Flake

Flake [Street Name]

Flex

Florida Snow

Foo Foo

Freeze

Girl

Girl [Street Name]

Gold dust

Gold Dust

Gold dust [Street Name]

Goofball

Green gold

Green Gold

G-Rock

Happy dust

Happy Dust

Happy dust [Street Name]

Happy powder

Happy Powder

Happy trails

Happy Trails

HCL, Cocaine

Heaven

Hell

HSDB 6469

Hydrochloride, cocaine

IDI1_000975

Isocaine

Isococain

Isococaine

Jam

KBio1_000975

Kibbles n' Bits

Kibbles N' Bits

Kokain

Kokan

Kokayeen

L000836

Lady

Lady [Street Name]

l-Cocain

L-Cocain

L-Cocaine

Leaf

LS-157759

methyl (1S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

methyl (3S,4R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid

Methyl 3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate

methyl 3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester)

Methyl benzoylecgonine

Methyl Benzoylecgonine

MLS002320697

MolPort-002-535-520

MolPort-003-937-722

Moonrocks

NCGC00159467-02

nchembio.284-comp4

Neurocaine

NINDS_000975

Nose candy

Pimp's drug

Pimp's Drug

Prime Time

Pseudoallococaine

Pseudococaine

Rock

Rock [Street Name]

Sleighride

SMR001338843

Snort

Snow

Snow (birds)

Star dust

Star Dust

Star-spangled powder

Star-Spangled Powder

STOCK1N-68258

Sugar

Sweet Stuff

Toke

Toot

Toot [Street Name]

Trails

UNII-I5Y540LHVR

White girl or lady

Yeyo

Zip

β-cocain

6

Narcotics

Phase 1

7

Narcotic Antagonists

Phase 1

8

Peripheral Nervous System Agents

Phase 1

9

Central Nervous System Depressants

Phase 1

10

Analgesics

Phase 1

11

Buprenorphine, Naloxone Drug Combination

Phase 1

12

Analgesics, Opioid

Phase 1

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Buprenorphine Naltrexone-P1 A-Cocaine	Completed	NCT00733720	Phase 1	Suboxone

Search NIH Clinical Center for Arthrogryposis, Distal, Type 6

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Sources

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Publications for Arthrogryposis, Distal, Type 6

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Variations for Arthrogryposis, Distal, Type 6

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Expression for Arthrogryposis, Distal, Type 6

Search GEO for disease gene expression data for Arthrogryposis, Distal, Type 6.

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Pathways for Arthrogryposis, Distal, Type 6

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GO Terms for Arthrogryposis, Distal, Type 6

Sources

Sources for Arthrogryposis, Distal, Type 6

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia

Arthrogryposis, Distal, Type 6 (DA6)

Aliases & Classifications for Arthrogryposis, Distal, Type 6

MalaCards integrated aliases for Arthrogryposis, Distal, Type 6:

Characteristics:

Orphanet epidemiological data:

OMIM:

HPO:

Classifications:

External Ids:

Summaries for Arthrogryposis, Distal, Type 6

Related Diseases for Arthrogryposis, Distal, Type 6

Diseases in the Distal Arthrogryposis family:

Diseases related to Arthrogryposis, Distal, Type 6 via text searches within MalaCards or GeneCards Suite gene sharing:

Symptoms & Phenotypes for Arthrogryposis, Distal, Type 6

Human phenotypes related to Arthrogryposis, Distal, Type 6:

Symptoms via clinical synopsis from OMIM:

Clinical features from OMIM:

Drugs & Therapeutics for Arthrogryposis, Distal, Type 6

Drugs for Arthrogryposis, Distal, Type 6 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Arthrogryposis, Distal, Type 6

Anatomical Context for Arthrogryposis, Distal, Type 6

Publications for Arthrogryposis, Distal, Type 6

Genes for Arthrogryposis, Distal, Type 6

Variations for Arthrogryposis, Distal, Type 6

Expression for Arthrogryposis, Distal, Type 6

Pathways for Arthrogryposis, Distal, Type 6

GO Terms for Arthrogryposis, Distal, Type 6

Sources for Arthrogryposis, Distal, Type 6