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MCID: ART023
MIFTS: 64

Arthropathy

Categories: Bone diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Arthropathy

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MalaCards integrated aliases for Arthropathy:

Name: Arthropathy 12 29 55 15 73
Joint Ankylosis of the Pelvic Region and Thigh 12
Ankylosis of Joint of Pelvic Region and Thigh 12
Joint Ankylosis of the Ankle and/or Foot 12
Ankylosis of Joint of Ankle and/or Foot 12
Joint Ankylosis of the Shoulder Region 12
Ankylosis of Joint of Shoulder Region 12
Joint Ankylosis of the Ankle and Foot 12
Arthropathy Associated with Infection 73
Ankylosis of Joint of Multiple Sites 12
Ankylosis of Ankle and Foot Joint 12
Joint Ankylosis of the Lower Leg 12
Joint Ankylosis of the Upper Arm 12
Ankylosis of Joint of Lower Leg 12
Ankylosis of Joint of Upper Arm 12
Joint Ankylosis of the Forearm 12
Ankylosis of Joint of Forearm 12
Ankylosis of Lower Leg Joint 12
Ankylosis of Multiple Joints 12
Ankylosis of Upper Arm Joint 12
Joint Ankylosis of the Hand 12
Ankylosis of Forearm Joint 12
Ankylosis of Joint of Hand 12
Ankylosis of Hand Joint 12
Infectious Arthropathy 12
Joint Diseases 44

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 33


Sources

Summaries for Arthropathy

About this section
Disease Ontology : 12 A bone disease that is located in the joint.

MalaCards based summary : Arthropathy, also known as joint ankylosis of the pelvic region and thigh, is related to hemophilic arthropathy and reactive arthritis, and has symptoms including joint stiffness, arthralgia and back pain. An important gene associated with Arthropathy is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Overview of nanoparticle effects and Transcription_Role of VDR in regulation of genes involved in osteoporosis. The drugs Etanercept and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and spinal cord, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia : 76 An arthropathy is a disease of a joint. Arthritis is a form of arthropathy that involves inflammation of... more...

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Related Diseases for Arthropathy

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Diseases in the Arthropathy family:

Transient Arthropathy

Diseases related to Arthropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 416)
# Related Disease Score Top Affiliating Genes
1 hemophilic arthropathy 33.0 COMP HFE TNFRSF11B TNFSF11
2 reactive arthritis 32.8 COMP CRP TNF
3 osteoarthritis 32.3 ACAN COMP PRG4 TNF
4 psoriatic arthritis 32.1 COMP CRP MICA TNF TNFRSF11B TNFSF11
5 multicentric reticulohistiocytosis 30.7 TNFRSF11B TNFSF11
6 pericarditis 30.6 CRP PRG4 TNF
7 chondrocalcinosis 30.5 ANKH HFE TNFRSF11B
8 arthritis 30.4 ACAN ANKH MICA TNF TNFSF11
9 spondylitis 30.1 CRP MICA TNF
10 rheumatoid arthritis 29.9 COMP CRP TNF TNFRSF11B TNFSF11
11 spondyloarthropathy 1 29.7 ANKH B2M CRP TNF TNFRSF11B
12 rheumatic disease 29.6 CRP TNF TNFRSF11B
13 myeloma, multiple 29.6 B2M CRP TNF TNFRSF11B TNFSF11
14 synovitis 29.5 COMP CRP PRG4 TNF TNFRSF11B TNFSF11
15 chronic meningitis 29.4 CRP NLRP3
16 tenosynovitis 29.4 COMP CRP
17 meningitis 29.4 CRP NLRP3 TNF
18 uremia 29.4 B2M CRP TNFRSF11B
19 bone inflammation disease 28.5 ACAN COMP CRP NLRP3 TNF TNFRSF11B
20 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.7
21 multicentric osteolysis, nodulosis, and arthropathy 12.5
22 crystal arthropathies 12.5
23 digital arthropathy-brachydactyly, familial 12.5
24 arthropathy, progressive pseudorheumatoid, of childhood 12.4
25 neurogenic arthropathy 12.4
26 mseleni joint disease 12.4
27 behcet's syndrome arthropathy 12.2
28 handigodu joint disease 12.2
29 transient arthropathy 12.1
30 multicentric osteolysis-nodulosis-arthropathy spectrum 12.1
31 arthropathy, erosive 12.0
32 progeria-associated arthropathy 11.9
33 chondrocalcinosis 2 11.9
34 familial calcium pyrophosphate deposition 11.9
35 handigodu disease 11.8
36 gout 11.7
37 joint disorders 11.5
38 hemochromatosis, type 2a 11.4
39 distal arthrogryposis 11.3
40 ankylosis 11.3
41 myhre syndrome 11.3
42 cinca syndrome 11.3
43 hemochromatosis type 2 11.3
44 wild type abeta2m amyloidosis 11.3
45 winchester syndrome 11.2
46 mitochondrial dna depletion syndrome 6 11.1
47 mpv17-related hepatocerebral mitochondrial dna depletion syndrome 11.1
48 atransferrinemia 11.0
49 xanthinuria, type i 11.0
50 chondrocalcinosis 1 11.0

Graphical network of the top 20 diseases related to Arthropathy:



Diseases related to Arthropathy
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Symptoms & Phenotypes for Arthropathy

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UMLS symptoms related to Arthropathy:


joint stiffness, arthralgia, back pain, sciatica, muscle cramp, metatarsalgia, joint symptom, musculoskeletal symptom, other symptoms referable to joint, stiffness of joint, not elsewhere classified in icd10cm, other symptoms referable to joint, shoulder region, other symptoms referable to joint, upper arm, other symptoms referable to joint, forearm, other symptoms referable to joint, hand, other symptoms referable to joint, pelvic region and thigh, other symptoms referable to joint, lower leg, other symptoms referable to joint, ankle and foot, other symptoms referable to joint, other specified sites, other symptoms referable to joint, multiple sites, other symptoms referable to joint, site unspecified

MGI Mouse Phenotypes related to Arthropathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 ANKH B2M COMP CRP F8 F9
2 growth/size/body region MP:0005378 10.17 ANKH B2M COMP HFE HGD MMP2
3 immune system MP:0005387 10.17 ANKH B2M COMP CRP F8 F9
4 cardiovascular system MP:0005385 10.16 ANKH B2M COMP CRP F9 MMP2
5 hematopoietic system MP:0005397 10.14 ANKH B2M F8 F9 HFE MMP2
6 limbs/digits/tail MP:0005371 9.86 ANKH COMP HFE NLRP3 TNF TNFRSF11B
7 liver/biliary system MP:0005370 9.7 B2M F9 HFE HGD NLRP3 TNF
8 muscle MP:0005369 9.5 ANKH COMP MMP2 TNF TNFSF11 TRPV4
9 skeleton MP:0005390 9.32 ANKH COMP HFE HGD MMP2 NLRP3
Sources

Drugs & Therapeutics for Arthropathy

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Drugs for Arthropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 963)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etanercept Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 185243-69-0
2
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 9004-61-9 53477741
3
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
4
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
5
Thrombin Approved, Investigational Phase 4,Not Applicable
6
Bevacizumab Approved, Investigational Phase 4 216974-75-3
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
8
Dalteparin Approved Phase 4,Phase 3 9005-49-6
9
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
10
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
11
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
12
Heparin Approved, Investigational Phase 4,Phase 3 9005-49-6 772 46507594
13
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
14
Glucosamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 3416-24-8 439213
15
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
16
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
17
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1177-87-3
18
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
19
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 378-44-9 9782
20
Ketorolac Approved Phase 4,Phase 3,Phase 2,Not Applicable 66635-83-4, 74103-06-3 3826
21
Iron Approved Phase 4,Phase 1,Phase 2,Not Applicable 7439-89-6 23925
22
Rivaroxaban Approved Phase 4,Phase 2,Phase 3,Not Applicable 366789-02-8
23
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22204-53-1 1302 156391
24
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
25
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 169590-42-5 2662
26
Chitosan Approved Phase 4,Phase 3,Not Applicable 9012-76-4 71853
27
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833
28
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 175805 71273
29
Cimetidine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 51481-61-9 2756
30
Hyoscyamine Approved Phase 4,Not Applicable 101-31-5 64692
31
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
32
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 51-41-2 439260
33
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 2180-92-9, 38396-39-3 2474
34
Tacrolimus Approved, Investigational Phase 4,Phase 3 104987-11-3 445643 439492
35
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 59-05-2, 1959-05-2 126941
36
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 332348-12-6 10237
37
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-05-9 6006 143
38
Sulfasalazine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 599-79-1 5353980 5359476
39
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2,Not Applicable 118-42-3 3652
40
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75706-12-6 3899
41
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
42
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
43
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 202409-33-4 123619
44
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 15307-86-5 3033
45
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 174722-31-7 10201696
46
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
47
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 16590-41-3 5360515
48
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 302-25-0
49
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83-43-2 6741
50
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 2921-57-5

Interventional clinical trials:

(show top 50) (show all 7525)
# Name Status NCT ID Phase Drugs
1 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
2 Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis Unknown status NCT00144820 Phase 4 Injection of Hyaluronan or Saline
3 A Clinical Phenotype Based Individualized Prophylaxis in Chinese Hemophilia A Children Unknown status NCT02999308 Phase 4
4 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
5 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
6 Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens Unknown status NCT02314325 Phase 4 ADVATE [Antihemophilic Factor (Recombinant)];ADVATE [Antihemophilic Factor (Recombinant)]
7 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
8 W-Shaped Acetabular Angular Plate (WAAP) Versus Reconstruction Plate Unknown status NCT02327949 Phase 4
9 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4 Human Fibrinogen and human thrombin (Evicel);Sodium Chlorure (Physiological saline)
10 Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic Synovitis Unknown status NCT02060305 Phase 4 Bevacizumab intra-articular injection
11 Additional Effects of Triamcinolone to Hyaluronic Acid on Knee Osteoarthritis Unknown status NCT02949466 Phase 4 Triamcinolone
12 Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty Unknown status NCT02865174 Phase 4 Topical tranexamic acid;Floseal®;Enoxaparin
13 Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection Unknown status NCT02835521 Phase 4 Joint injection with triamcinolone hexacetonide
14 Intra-articular Botox Type A Versus Corticosteroids in Knee Osteoarthritis Unknown status NCT02829281 Phase 4 Botulinum Toxin Type A;Triamcinolone hexacetonide;Saline
15 Primary Care Study With Chondroitin Sulfate and Glucosamine Hydrochloride in Hand Osteoarhritis Unknown status NCT02823548 Phase 4 Droglican;Placebo
16 Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN Unknown status NCT02821468 Phase 4 Droglican;Paracetamol or oral NSAIDs excluding COX2 inhibitors
17 Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial Unknown status NCT02760459 Phase 4 Dexamethasone;Normal saline solution
18 Assessment of a Knee Brace in Patients With Osteoarthritis Unknown status NCT02706106 Phase 4
19 Effectiveness of Trapeziometacarpal Splint Unknown status NCT02635932 Phase 4
20 26 Week Open Label Study Evaluating Single IA Injection of DUROLANE SJ for Treatment of Osteoarthritis Pain of the Ankle Unknown status NCT02627859 Phase 4
21 Effects of Hyaluronic Acid vs. Hyaluronic Acid on Knee Osteoarthritis Unknown status NCT02625727 Phase 4
22 Comparing Intra-articular Corticosteroid to Intra-articular Ketorolac Knee Injections Unknown status NCT02612272 Phase 4 Ketorolac;Betamethasone
23 Intravenous Iron Sucrose in Arthroplasty Unknown status NCT02544828 Phase 4 Iron Sucrose 200mg;placebo
24 The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy Unknown status NCT02539069 Phase 4
25 The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) Unknown status NCT02539056 Phase 4
26 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4 Guli capsule;Kangguzengsheng capsule
27 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
28 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
29 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
30 Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE) Unknown status NCT02323451 Phase 4 Sodium Hyaluronate Injection
31 Tranexamic Acid in Knee Joint Surgery Unknown status NCT02278263 Phase 4 Tranexamic Acid;Normal saline (0.9% NaCl)
32 Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty Unknown status NCT02152917 Phase 4 Tranexamic acid;Floseal®
33 Intraarticular Xylitol Injections for Knee Osteoarthritis Unknown status NCT02104596 Phase 4
34 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4 spironolactone
35 Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy Unknown status NCT02000297 Phase 4
36 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4 Imrecoxib
37 Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR) Unknown status NCT01973530 Phase 4
38 Reinflation After Early Tourniquet Release in Total Knee Arthroplasty Unknown status NCT01832272 Phase 4
39 Hip Viscosupplementation: What is the Best Dosage? Unknown status NCT01810809 Phase 4 1 ampoule of Hylan GF-20;2 ampoules of Hylan GF-20;3 ampoules of Hylan GF-20
40 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
41 RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem Unknown status NCT01618084 Phase 4
42 Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis Unknown status NCT01329406 Phase 4 Milnacipran;Placebo
43 Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Unknown status NCT01233739 Phase 4 Chondroitin sulfate;Placebo
44 Assessment of the Effects of Chondroitin Sulphate in Patients With Knee Osteoarthritis With Functional Magnetic Resonance Imaging (fMRI) Unknown status NCT01226615 Phase 4 Chondroitin sulphate (Condrosan®);Placebo
45 Prophecy Guide Outcomes in Total Knee Replacement Surgery Unknown status NCT01163708 Phase 4
46 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
47 Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty Unknown status NCT01027819 Phase 4
48 The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics Unknown status NCT00778076 Phase 4
49 Use of Cold and Compression Therapy With Total Knee Replacement Patients Unknown status NCT00712816 Phase 4
50 Trial Comparing Navigated and Conventional Implantation Techniques in Knee Replacement Surgery Unknown status NCT00431509 Phase 4

Search NIH Clinical Center for Arthropathy

Cochrane evidence based reviews: joint diseases

Sources

Genetic Tests for Arthropathy

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Genetic tests related to Arthropathy:

# Genetic test Affiliating Genes
1 Arthropathy 29
Sources

Anatomical Context for Arthropathy

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MalaCards organs/tissues related to Arthropathy:

41
Bone, Testes, Spinal Cord, T Cells, Heart, Kidney, Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Arthropathy:

19
The Joint
Sources

Publications for Arthropathy

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Articles related to Arthropathy:

(show top 50) (show all 1341)
# Title Authors Year
1
Postural control during a transition task in haemophilic children, adolescents and young adults with haemophilic ankle arthropathy. ( 29673013 )
2018
2
Mid-term outcomes of routine proximal row carpectomy compared with proximal row carpectomy with dorsal capsular interposition arthroplasty for the treatment of late-stage arthropathy of the wrist. ( 29437062 )
2018
3
Range of motion after total knee arthroplasty in hemophilic arthropathy. ( 29788949 )
2018
4
Safety of intra-articular transplantation of lentivirally transduced mesenchymal stromal cells for haemophilic arthropathy in a non-human primate. ( 29737459 )
2018
5
Primary Total Hip Arthroplasty for Charcot Arthropathy is Associated With High Complications but Improved Clinical Outcomes. ( 29706256 )
2018
6
Dynamic contrast-enhanced magnetic resonance imaging for differentiating osteomyelitis from acute neuropathic arthropathy in the complicated diabetic foot. ( 29654348 )
2018
7
Acute locked superior shoulder dislocation in a patient with cuff tear arthropathy. ( 29930172 )
2018
8
Erosive Gouty Arthropathy Resulting in a Telescoping Digit. ( 29794875 )
2018
9
Advanced Hemophilic Arthropathy: Sensitivity of Soft Tissue Discrimination With Musculoskeletal Ultrasound. ( 29363781 )
2018
10
Diabetic foot syndrome: Charcot arthropathy or osteomyelitis? Part I: Clinical picture and radiography. ( 29844940 )
2018
11
Synovectomy using Samarium-153 Hydroxyapatite in the Elbows and Ankles of Patients with Hemophilic Arthropathy. ( 29398959 )
2018
12
Safety and effectiveness of fascial therapy in adult patients with hemophilic arthropathy. A pilot study. ( 29334292 )
2018
13
Joint lavage followed by intra-articular injection of hyaluronic acid and/or corticosteroids in patients with severe hemophilic arthropathy of the knee: Is this intervention really effective? ( 29722575 )
2018
14
Association of CXCL13 serum level and ultrasonographic findings of joints in patients with systemic lupus erythematosus and Jaccoud's arthropathy. ( 29338586 )
2018
15
Clinical and Radiological Evaluation After Chemical Synovectomy With Rifampicin in Hemophilic Arthropathy: Korean Experience With a 2-Week Interval Protocol. ( 29961743 )
2018
16
Safety of fascial therapy in adult patients with hemophilic arthropathy of ankle. A cohort study. ( 29550698 )
2018
17
Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome. ( 29397575 )
2018
18
Management of autonomic dysreflexia associated with Charcot spinal arthropathy in a patient with complete spinal cord injury: Case report and review of the literature. ( 29930879 )
2018
19
Risk and risk factors for revision after primary reverse shoulder arthroplasty for cuff tear arthropathy and osteoarthritis: a Nordic Arthroplasty Register Association study. ( 29779980 )
2018
20
Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. ( 29922458 )
2018
21
Syringomyelia with left knee charcot arthropathy: a case report. ( 29405778 )
2018
22
Missing angiogenic factors in hemophilic arthropathy. ( 29103337 )
2018
23
Arthroscopic soft-tissue interposition arthroplasty of the glenohumeral joint for ochronotic arthropathy: A case report. ( 29361375 )
2018
24
Imaging of Progressive Neuropathic Arthropathy of The Shoulder. ( 29979203 )
2018
25
Charcot spinal arthropathy. ( 29755231 )
2018
26
Primary Total Knee Arthroplasty in Patients With Neuropathic (Charcot) Arthropathy: Contemporary Results. ( 29706257 )
2018
27
Autoimmune temporomandibular arthropathy: diagnostic considerations. ( 29964250 )
2018
28
Radiological features of crystal-induced arthropathy associated with hereditary hemochromatosis with homozygous C282Y mutation. ( 29731342 )
2018
29
Simultaneous bilateral total knee arthroplasty in patients with end-stage hemophilic arthropathy: a mean follow-up of 6 years. ( 29371670 )
2018
30
Neuropathic Arthropathy of the Glenohumeral Joint A Review of the Literature. ( 29799367 )
2018
31
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNFI+ pathway. ( 29776906 )
2018
32
Quantification of physical activity in adult patients with haemophilic arthropathy in prophylaxis treatment using a fitness tracker. ( 29271553 )
2018
33
Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family. ( 30511553 )
2018
34
Knee Arthroscopy: A Diagnostic and Therapeutic Tool for Management of Ochronotic Arthropathy. ( 30533354 )
2018
35
Clinical Features and Treatment of Down Syndrome Arthropathy: Experience from Two US Tertiary Hospitals. ( 30547384 )
2018
36
Jaccoud's Arthropathy and Jaundice in a Young Female. ( 30557734 )
2018
37
Heel pain in psoriatic arthropathy: Analysis of a series of 291 patients. ( 28576643 )
2018
38
Health-Related Quality of Life and Association With Arthropathy in Greek Patients with Hemophilia. ( 28992766 )
2018
39
Hybrid Fixation for Ankle Fusion in Diabetic Charcot Arthropathy. ( 29035584 )
2018
40
Angiographic assessment of atherosclerotic load at the lower extremity in patients with diabetic foot and charcot neuro-arthropathy. ( 29056486 )
2018
41
Response to: missing angiogenic factors in hemophilic arthropathy. ( 29092644 )
2018
42
MRI ankle and subtalar characteristics in haemochromatosis arthropathy: a case-control study. ( 29126545 )
2018
43
Treating Charcot Arthropathy Is a Challenge: Explaining Why My Treatment Algorithm Has Changed. ( 29156160 )
2018
44
Intra-articular corticosteroid injections in haemophilic arthropathy: are they recommended? ( 29172843 )
2018
45
Mid-term outcomes and complications of total knee arthroplasty in haemophilic arthropathy: A review of consecutive 131 knees between 2006 and 2015 in a single institute. ( 29193440 )
2018
46
Crystalline arthropathy and bone health. ( 29194109 )
2018
47
Characteristics of children with acute lymphoblastic leukemia presenting with arthropathy. ( 29464526 )
2018
48
Injury to the axillary and suprascapular nerves in rotator cuff arthropathy and after reverse shoulder arthroplasty: a prospective electromyographic analysis. ( 29475786 )
2018
49
Physiotherapist inter-rater reliability of the Haemophilia Early Arthropathy Detection with Ultrasound protocol. ( 29493853 )
2018
50
Beekeeper' arthropathy. ( 29530760 )
2018
Sources

Variations for Arthropathy

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Expression for Arthropathy

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Search GEO for disease gene expression data for Arthropathy.
Sources

Pathways for Arthropathy

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Pathways related to Arthropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Overview of nanoparticle effects 1
10.54 CRP TNF
2
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
10.45 TNF TNFRSF11B TNFSF11
3
Osteoclast Signaling 1
10.36 TNFRSF11B TNFSF11
4
Osteoblast Signaling 1
10.1 TNFRSF11B TNFSF11
Sources

GO Terms for Arthropathy

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Cellular components related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 ACAN B2M CCN6 COMP CRP F8
2 collagen-containing extracellular matrix GO:0062023 9.67 ACAN COMP MMP2 PRG4
3 extracellular matrix GO:0031012 9.55 ACAN CCN6 COMP MMP2 TNFRSF11B
4 extracellular space GO:0005615 9.4 B2M CCN6 COMP CRP F8 F9
5 MHC class I protein complex GO:0042612 9.32 B2M HFE
6 HFE-transferrin receptor complex GO:1990712 9.26 B2M HFE

Biological processes related to Arthropathy according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.8 ACAN COMP TNF TNFRSF11B
2 animal organ morphogenesis GO:0009887 9.77 COMP TNF TNFSF11
3 defense response to Gram-positive bacterium GO:0050830 9.74 CRP NLRP3 TNF
4 immune response GO:0006955 9.73 B2M HFE MICA PRG4 TNF TNFSF11
5 positive regulation of JNK cascade GO:0046330 9.72 TNF TNFSF11 TRPV4
6 skeletal system development GO:0001501 9.71 ACAN ANKH COMP TNFRSF11B
7 tumor necrosis factor-mediated signaling pathway GO:0033209 9.69 TNF TNFRSF11B TNFSF11
8 T cell mediated cytotoxicity GO:0001913 9.59 HFE MICA
9 blood coagulation, intrinsic pathway GO:0007597 9.58 F8 F9
10 regulation of osteoclast differentiation GO:0045670 9.58 TNF TNFSF11
11 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.56 HFE MICA
12 growth plate cartilage development GO:0003417 9.54 COMP ZMPSTE24
13 acute-phase response GO:0006953 9.54 CRP F8 HFE
14 negative regulation of lipid storage GO:0010888 9.52 CRP TNF
15 cellular response to iron ion GO:0071281 9.48 B2M HFE
16 negative regulation of receptor binding GO:1900121 9.46 B2M HFE
17 positive regulation of receptor binding GO:1900122 9.43 B2M HFE
18 regulation of iron ion import GO:1900390 9.32 B2M HFE
19 positive regulation of ferrous iron binding GO:1904434 9.16 B2M HFE
20 positive regulation of gene expression GO:0010628 9.1 CRP HFE TNF TNFSF11 TRPV4 ZMPSTE24
21 positive regulation of transferrin receptor binding GO:1904437 8.96 B2M HFE

Molecular functions related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.8 B2M CRP HGD NLRP3 TNF TRPV4
2 extracellular matrix structural constituent conferring compression resistance GO:0030021 9.26 ACAN PRG4
3 natural killer cell lectin-like receptor binding GO:0046703 8.96 HFE MICA
4 beta-2-microglobulin binding GO:0030881 8.62 HFE MICA
5 protein binding GO:0005515 10.06 ACAN B2M COMP CRP F8 F9
Sources

Sources for Arthropathy

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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