Aliases & Classifications for Arthropathy

MalaCards integrated aliases for Arthropathy:

Name: Arthropathy 12 30 56 15 74
Joint Ankylosis of the Pelvic Region and Thigh 12
Ankylosis of Joint of Pelvic Region and Thigh 12
Joint Ankylosis of the Ankle and/or Foot 12
Ankylosis of Joint of Ankle and/or Foot 12
Joint Ankylosis of the Shoulder Region 12
Ankylosis of Joint of Shoulder Region 12
Joint Ankylosis of the Ankle and Foot 12
Arthropathy Associated with Infection 74
Ankylosis of Joint of Multiple Sites 12
Ankylosis of Ankle and Foot Joint 12
Joint Ankylosis of the Lower Leg 12
Joint Ankylosis of the Upper Arm 12
Ankylosis of Joint of Lower Leg 12
Ankylosis of Joint of Upper Arm 12
Joint Ankylosis of the Forearm 12
Ankylosis of Joint of Forearm 12
Ankylosis of Lower Leg Joint 12
Ankylosis of Multiple Joints 12
Ankylosis of Upper Arm Joint 12
Joint Ankylosis of the Hand 12
Ankylosis of Forearm Joint 12
Ankylosis of Joint of Hand 12
Ankylosis of Hand Joint 12
Infectious Arthropathy 12
Joint Diseases 45
Joint Disease 17

Classifications:



Summaries for Arthropathy

Disease Ontology : 12 A bone disease that is located in the joint.

MalaCards based summary : Arthropathy, also known as joint ankylosis of the pelvic region and thigh, is related to reactive arthritis and hemophilic arthropathy, and has symptoms including joint stiffness, arthralgia and back pain. An important gene associated with Arthropathy is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Overview of nanoparticle effects and Transcription_Role of VDR in regulation of genes involved in osteoporosis. The drugs Adalimumab and Etanercept have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and eye, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia : 77 An arthropathy is a disease of a joint. Arthritis is a form of arthropathy that involves inflammation of... more...

Related Diseases for Arthropathy

Diseases in the Arthropathy family:

Transient Arthropathy

Diseases related to Arthropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 499)
# Related Disease Score Top Affiliating Genes
1 reactive arthritis 32.9 COMP CRP TNF
2 hemophilic arthropathy 32.9 COMP HFE TNFRSF11B TNFSF11
3 osteoarthritis 32.4 ACAN COMP PRG4 TNF
4 psoriatic arthritis 31.9 COMP CRP MICA TNF TNFRSF11B TNFSF11
5 chondrocalcinosis 30.8 ANKH HFE TNFRSF11B
6 pericarditis 30.8 CRP PRG4 TNF
7 multicentric reticulohistiocytosis 30.7 TNFRSF11B TNFSF11
8 spondylitis 30.6 CRP MICA TNF
9 arthritis 30.4 ACAN ANKH MICA TNF TNFSF11
10 spondyloarthropathy 1 29.9 ANKH B2M CRP TNF TNFRSF11B
11 rheumatic disease 29.8 CRP TNF TNFRSF11B
12 rheumatoid arthritis 29.8 COMP CRP TNF TNFRSF11B TNFSF11
13 peritonitis 29.5 B2M CRP TNF
14 myeloma, multiple 29.5 B2M CRP TNF TNFRSF11B TNFSF11
15 uremia 29.4 B2M CRP TNFRSF11B
16 tenosynovitis 29.4 COMP CRP
17 familial mediterranean fever 29.4 CRP NLRP3 TNF
18 chronic meningitis 29.4 CRP NLRP3
19 meningitis 29.4 CRP NLRP3 TNF
20 synovitis 29.3 COMP CRP PRG4 TNF TNFRSF11B TNFSF11
21 bone disease 28.8 ACAN B2M TNF TNFRSF11B TNFSF11
22 bone inflammation disease 28.0 ACAN COMP CRP NLRP3 TNF TNFRSF11B
23 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.7
24 multicentric osteolysis, nodulosis, and arthropathy 12.6
25 arthropathy, progressive pseudorheumatoid, of childhood 12.6
26 crystal arthropathies 12.6
27 digital arthropathy-brachydactyly, familial 12.5
28 neurogenic arthropathy 12.4
29 mseleni joint disease 12.4
30 behcet's syndrome arthropathy 12.2
31 handigodu joint disease 12.2
32 transient arthropathy 12.2
33 multicentric osteolysis-nodulosis-arthropathy spectrum 12.2
34 arthropathy, erosive 12.1
35 chondrocalcinosis 2 12.0
36 familial calcium pyrophosphate deposition 11.9
37 handigodu disease 11.9
38 joint disorders 11.8
39 gout 11.7
40 jaccoud's syndrome 11.6
41 hemochromatosis, type 2a 11.5
42 distal arthrogryposis 11.4
43 myhre syndrome 11.3
44 cinca syndrome 11.3
45 ankylosis 11.3
46 wild type abeta2m amyloidosis 11.3
47 hemochromatosis type 2 11.3
48 mandibuloacral dysplasia with type a lipodystrophy 11.3
49 winchester syndrome 11.2
50 mitochondrial dna depletion syndrome 6 11.1

Graphical network of the top 20 diseases related to Arthropathy:



Diseases related to Arthropathy

Symptoms & Phenotypes for Arthropathy

UMLS symptoms related to Arthropathy:


joint stiffness, arthralgia, back pain, sciatica, muscle cramp, metatarsalgia, joint symptom, musculoskeletal symptom, other symptoms referable to joint, stiffness of joint, not elsewhere classified in icd10cm, other symptoms referable to joint, shoulder region, other symptoms referable to joint, upper arm, other symptoms referable to joint, forearm, other symptoms referable to joint, hand, other symptoms referable to joint, pelvic region and thigh, other symptoms referable to joint, lower leg, other symptoms referable to joint, ankle and foot, other symptoms referable to joint, other specified sites, other symptoms referable to joint, multiple sites, other symptoms referable to joint, site unspecified

MGI Mouse Phenotypes related to Arthropathy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 ANKH B2M COMP CRP F8 F9
2 growth/size/body region MP:0005378 10.17 ANKH B2M COMP HFE HGD MMP2
3 immune system MP:0005387 10.17 ANKH B2M COMP CRP F8 F9
4 cardiovascular system MP:0005385 10.16 ANKH B2M COMP CRP F9 MMP2
5 hematopoietic system MP:0005397 10.14 ANKH B2M F8 F9 HFE MMP2
6 limbs/digits/tail MP:0005371 9.86 ANKH COMP HFE NLRP3 TNF TNFRSF11B
7 liver/biliary system MP:0005370 9.7 B2M F9 HFE HGD NLRP3 TNF
8 muscle MP:0005369 9.5 ANKH COMP MMP2 TNF TNFSF11 TRPV4
9 skeleton MP:0005390 9.32 ANKH COMP HFE HGD MMP2 NLRP3

Drugs & Therapeutics for Arthropathy

Drugs for Arthropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1023)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
2
Etanercept Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 185243-69-0
3
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 9004-61-9 53477741
4
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
5
Azithromycin Approved Phase 4,Phase 3 83905-01-5 447043 55185
6
Thrombin Approved, Investigational Phase 4,Not Applicable
7
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
8
Rivaroxaban Approved Phase 4,Phase 2,Phase 3,Not Applicable 366789-02-8
9
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
10
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
11
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 169590-42-5 2662
12
Dalteparin Approved Phase 4,Phase 3 9005-49-6
13
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
14
Heparin Approved, Investigational Phase 4,Phase 3,Not Applicable 9005-49-6 46507594 772
15
Acetylcholine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
16
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 15307-86-5 3033
17
Glucosamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 3416-24-8 439213
18
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
19
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
20
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1177-87-3
21
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
22
Ketorolac Approved Phase 4,Phase 3,Phase 2,Not Applicable 74103-06-3, 66635-83-4 3826
23
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 378-44-9 9782
24
Iron Approved, Experimental Phase 4,Phase 1,Phase 2,Not Applicable 7439-89-6, 15438-31-0 27284 23925
25
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22204-53-1 156391 1302
26
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
27
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
28
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 175805 71273
29
Cimetidine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 51481-61-9 2756
30
Hyoscyamine Approved Phase 4,Not Applicable 101-31-5 64692
31
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 51-41-2 439260
32
Levomilnacipran Approved, Investigational Phase 4 96847-54-0
33
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
34
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 38396-39-3, 2180-92-9 2474
35
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-05-9 143 6006
36
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1959-05-2, 59-05-2 126941
37
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 332348-12-6 10237
38
Sulfasalazine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 599-79-1 5359476 5353980
39
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2,Not Applicable 118-42-3 3652
40
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75706-12-6 3899
41
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
42
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
43
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 202409-33-4 123619
44
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 174722-31-7 10201696
45
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 2921-57-5
46
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 302-25-0
47
Ethanol Approved Phase 4,Phase 3,Phase 2,Not Applicable 64-17-5 702
48
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 16590-41-3 5360515
49
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
50
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83-43-2 6741

Interventional clinical trials:

(show top 50) (show all 8009)
# Name Status NCT ID Phase Drugs
1 Study of Adalimumab to Lower Cardiovascular Risk in RA Patients With Well Controlled Joint Disease Unknown status NCT01893996 Phase 4 Adalimumab;Placebo
2 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
3 Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis Unknown status NCT00144820 Phase 4 Injection of Hyaluronan or Saline
4 A Clinical Phenotype Based Individualized Prophylaxis in Chinese Hemophilia A Children Unknown status NCT02999308 Phase 4
5 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
6 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
7 Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens Unknown status NCT02314325 Phase 4 ADVATE [Antihemophilic Factor (Recombinant)];ADVATE [Antihemophilic Factor (Recombinant)]
8 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
9 W-Shaped Acetabular Angular Plate (WAAP) Versus Reconstruction Plate Unknown status NCT02327949 Phase 4
10 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4 Human Fibrinogen and human thrombin (Evicel);Sodium Chlorure (Physiological saline)
11 Combined Topical Tranexamic Acid With Floseal® in Total Knee Arthroplasty Unknown status NCT03328832 Phase 4 Topical tranexamic acid;Floseal®;rivaroxaban (10mg)
12 Outcomes of Injections in Patients Waiting for Total Knee Replacement Unknown status NCT03090698 Phase 4 Hylan G-F 20;Triamcinolone
13 The Study to Evaluate Efficacy and Safety of Celecoxib Capsule in Hand Osteoarthritis Patients Unknown status NCT03067194 Phase 4 Celecoxib 100 MG;Celecoxib 200mg
14 Additional Effects of Triamcinolone to Hyaluronic Acid on Knee Osteoarthritis Unknown status NCT02949466 Phase 4 Triamcinolone
15 Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty Unknown status NCT02865174 Phase 4 Topical tranexamic acid;Floseal®;Enoxaparin
16 Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection Unknown status NCT02835521 Phase 4 Joint injection with triamcinolone hexacetonide
17 Intra-articular Botox Type A Versus Corticosteroids in Knee Osteoarthritis Unknown status NCT02829281 Phase 4 Botulinum Toxin Type A;Triamcinolone hexacetonide;Saline
18 Clinical Study of Artz in the Treatment of Knee Osteoarthritis Unknown status NCT02826031 Phase 4 Sodium Hyaluronate Injection;DICL-SR
19 Primary Care Study With Chondroitin Sulfate and Glucosamine Hydrochloride in Hand Osteoarhritis Unknown status NCT02823548 Phase 4 Droglican;Placebo
20 Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN Unknown status NCT02821468 Phase 4 Droglican;Paracetamol or oral NSAIDs excluding COX2 inhibitors
21 Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial Unknown status NCT02760459 Phase 4 Dexamethasone;Normal saline solution
22 Assessment of a Knee Brace in Patients With Osteoarthritis Unknown status NCT02706106 Phase 4
23 Effectiveness of Trapeziometacarpal Splint Unknown status NCT02635932 Phase 4
24 26 Week Open Label Study Evaluating Single IA Injection of DUROLANE SJ for Treatment of Osteoarthritis Pain of the Ankle Unknown status NCT02627859 Phase 4
25 Effects of Hyaluronic Acid vs. Hyaluronic Acid on Knee Osteoarthritis Unknown status NCT02625727 Phase 4
26 Comparing Intra-articular Corticosteroid to Intra-articular Ketorolac Knee Injections Unknown status NCT02612272 Phase 4 Ketorolac;Betamethasone
27 Intravenous Iron Sucrose in Arthroplasty Unknown status NCT02544828 Phase 4 Iron Sucrose 200mg;placebo
28 The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy Unknown status NCT02539069 Phase 4
29 The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) Unknown status NCT02539056 Phase 4
30 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4 Guli capsule;Kangguzengsheng capsule
31 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
32 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
33 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
34 Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE) Unknown status NCT02323451 Phase 4 Sodium Hyaluronate Injection
35 Tranexamic Acid in Knee Joint Surgery Unknown status NCT02278263 Phase 4 Tranexamic Acid;Normal saline (0.9% NaCl)
36 Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty Unknown status NCT02152917 Phase 4 Tranexamic acid;Floseal®
37 Intraarticular Xylitol Injections for Knee Osteoarthritis Unknown status NCT02104596 Phase 4
38 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4 spironolactone
39 Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy Unknown status NCT02000297 Phase 4
40 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4 Imrecoxib
41 Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR) Unknown status NCT01973530 Phase 4
42 Reinflation After Early Tourniquet Release in Total Knee Arthroplasty Unknown status NCT01832272 Phase 4
43 Hip Viscosupplementation: What is the Best Dosage? Unknown status NCT01810809 Phase 4 1 ampoule of Hylan GF-20;2 ampoules of Hylan GF-20;3 ampoules of Hylan GF-20
44 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
45 RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem Unknown status NCT01618084 Phase 4
46 Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis Unknown status NCT01329406 Phase 4 Milnacipran;Placebo
47 Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Unknown status NCT01233739 Phase 4 Chondroitin sulfate;Placebo
48 Assessment of the Effects of Chondroitin Sulphate in Patients With Knee Osteoarthritis With Functional Magnetic Resonance Imaging (fMRI) Unknown status NCT01226615 Phase 4 Chondroitin sulphate (Condrosan®);Placebo
49 Prophecy Guide Outcomes in Total Knee Replacement Surgery Unknown status NCT01163708 Phase 4
50 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg

Search NIH Clinical Center for Arthropathy

Cochrane evidence based reviews: joint diseases

Genetic Tests for Arthropathy

Genetic tests related to Arthropathy:

# Genetic test Affiliating Genes
1 Arthropathy 30

Anatomical Context for Arthropathy

MalaCards organs/tissues related to Arthropathy:

42
Bone, Testes, Eye, Bone Marrow, Breast, Heart, T Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Arthropathy:

20
The Joint

Publications for Arthropathy

Articles related to Arthropathy:

(show top 50) (show all 2407)
# Title Authors Year
1
Arthropathy in acromegaly: a questionnaire-based estimation of motor disability and its relation with quality of life and work productivity. ( 31032537 )
2019
2
Massive acromio-clavicular joint ganglion cyst associated with cuff tear arthropathy and acromioclavicular joint arthritis with normal functional shoulder-A case report. ( 31061582 )
2019
3
MR neurography showed brachial plexus abnormalities in syringomyelia with shoulder Charcot arthropathy: a case report. ( 30892961 )
2019
4
Risks and patient outcomes of surgical intervention for hemophilic arthropathy. ( 30929534 )
2019
5
Overlapping features of rapidly progressive osteoarthrosis and Charcot arthropathy. ( 30936675 )
2019
6
Using synovial volume measurement by MRI to evaluate the effect of 32P Radiation synovectomy on hemophilic arthropathy patients. ( 30958324 )
2019
7
Monitoring Bone Health in Children with Hemophilic Arthropathy: Where Do We Stand? ( 30972699 )
2019
8
Chronic postrheumatic fever arthropathy. ( 30978163 )
2019
9
Commentary on the paper: "Hindfoot malalignment in adults with haemophilic ankle arthropathy: The importance of early detection and orthotic treatment": Authored by: De la Corte-Rodriguez, Rodriguez-Merchan, Alvarez-Roman, Martin-Salces, Jimenez-Yuste. ( 30994252 )
2019
10
Low-dose computed tomography as diagnostic tool in calcium pyrophosphate deposition disease arthropathy: focus on ligamentous calcifications of the wrist. ( 31025927 )
2019
11
Familial Mediterranean Fever Gene Mutations and Gout as an Auto-Inflammatory Arthropathy. ( 31097862 )
2019
12
Imaging of Progressive Neuropathic Arthropathy of the Shoulder. ( 29979203 )
2019
13
Subgroups of patients with osteoarthritis and medial meniscus tear or crystal arthropathy benefit from arthroscopic treatment. ( 30128683 )
2019
14
Ultrasound-Guided Prolotherapy for Acromial Enthesopathy and Acromioclavicular Joint Arthropathy: A Single-Arm Prospective Study. ( 30171616 )
2019
15
Models of arthropathy: what can we learn from them to improve patient care? ( 30239955 )
2019
16
Glenohumeral Dislocation Arthropathy: Etiology, Diagnosis, and Management. ( 30278009 )
2019
17
Corrigendum to "Primary Total Knee Arthroplasty in Patients With Neuropathic (Charcot) Arthropathy: Contemporary Results" [Journal of Arthroplasty 33 (2018) 2815-2820]. ( 30293755 )
2019
18
Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis-an ultrasound study. ( 30327988 )
2019
19
Assessment of tensile mechanical properties of the Achilles tendon in adult patients with haemophilic arthropathy. Reproducibility study. ( 30375147 )
2019
20
Clinical effectiveness and safety of the extended humeral head arthroplasty for selected patients with rotator cuff tear arthropathy. ( 30392935 )
2019
21
Clinicopathological case: rapid cognitive decline and myoclonus associated with fever, arthropathy and scleritis. ( 30425126 )
2019
22
Joint status in Spanish haemophilia B patients assessed using the Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score. ( 30444298 )
2019
23
Charcot spinal arthropathy presenting as adjacent segment disease after lumbar spinal fusion surgery in Parkinson's disease: A case report. ( 30446371 )
2019
24
Glenoid morphology is associated with the development of instability arthropathy. ( 30509607 )
2019
25
Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy. ( 30648774 )
2019
26
Hindfoot malalignment in adults with haemophilic ankle arthropathy: The importance of early detection and orthotic treatment. ( 30664313 )
2019
27
Poor patient-reported outcome after shoulder replacement in young patients with cuff-tear arthropathy: a matched-pair analysis from the Danish Shoulder Arthroplasty Registry. ( 30669910 )
2019
28
Serum Sclerostin Level and Bone Mineral Density in Pediatric Hemophilic Arthropathy. ( 30671760 )
2019
29
Arthropathy and Cutaneous Eruption in a Patient With Cystic Fibrosis. ( 30673074 )
2019
30
Clinical manifestations and risk factors of arthropathy in cystic fibrosis. ( 30704701 )
2019
31
Assessment of haemophilic arthropathy through balance analysis: a promising tool. ( 30714398 )
2019
32
The Prevalence of Asymptomatic Cervical and Lumbar Facet Arthropathy: A Computed Tomography Study. ( 30744307 )
2019
33
Neuromuscular control during gait in people with haemophilic arthropathy. ( 30748060 )
2019
34
Syphilis with Charcot arthropathy: a case report. ( 30758895 )
2019
35
Can a functional difference be detected in reverse arthroplasty with 135° versus 155° prosthesis for the treatment of rotator cuff arthropathy: a prospective randomized study. ( 30773441 )
2019
36
Facet arthropathy evaluation: CT or MRI? ( 30796571 )
2019
37
Humeral head histopathological changes in cuff tear arthropathy. ( 30798768 )
2019
38
Neuropathic arthropathy of the shoulder joint caused by syringomyelia: report of a rare case. ( 30850574 )
2019
39
Pressure distribution under the contralateral limb in Charcot arthropathy with different walking speeds. ( 30851651 )
2019
40
Long-term results of total knee arthroplasty in hemophilic arthropathy. ( 30852987 )
2019
41
An exploratory comparison of single intra-articular injection of platelet-rich plasma vs hyaluronic acid in treatment of haemophilic arthropathy of the knee. ( 30866117 )
2019
42
Outpatient treatment for haemophilic arthropathy with radiosynovectomy: Radiation dose to family members. ( 30866133 )
2019
43
Anterior osteophyte resection of the ankle joint to increase range of motion in haemophilic ankle arthropathy. ( 30866148 )
2019
44
Destructive arthropathy of the shoulder complicating a cervical ependymoma. ( 30890366 )
2019
45
Injury to the axillary and suprascapular nerves in rotator cuff arthropathy and after reverse shoulder arthroplasty: a prospective electromyographic analysis. ( 29475786 )
2018
46
Physiotherapist inter-rater reliability of the Haemophilia Early Arthropathy Detection with Ultrasound protocol. ( 29493853 )
2018
47
Beekeeper' arthropathy. ( 29530760 )
2018
48
Prevalence of Charcot Arthropathy in Type 2 Diabetes Patients Aged over 50 Years with Severe Peripheral Neuropathy: A Retrospective Study in a Tertiary Care South Indian Hospital. ( 29535947 )
2018
49
Safety of fascial therapy in adult patients with hemophilic arthropathy of ankle. A cohort study. ( 29550698 )
2018
50
Assessment of passive musculoarticular ankle stiffness in children, adolescents and young adults with haemophilic ankle arthropathy. ( 29600577 )
2018

Variations for Arthropathy

Expression for Arthropathy

Search GEO for disease gene expression data for Arthropathy.

Pathways for Arthropathy

Pathways related to Arthropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 CRP TNF
2 10.45 TNF TNFRSF11B TNFSF11
3 10.36 TNFRSF11B TNFSF11
4 10.1 TNFRSF11B TNFSF11

GO Terms for Arthropathy

Cellular components related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 ACAN B2M CCN6 COMP CRP F8
2 collagen-containing extracellular matrix GO:0062023 9.67 ACAN COMP MMP2 PRG4
3 extracellular matrix GO:0031012 9.55 ACAN CCN6 COMP MMP2 TNFRSF11B
4 extracellular space GO:0005615 9.4 B2M CCN6 COMP CRP F8 F9
5 MHC class I protein complex GO:0042612 9.32 B2M HFE
6 HFE-transferrin receptor complex GO:1990712 9.26 B2M HFE

Biological processes related to Arthropathy according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.78 ACAN COMP TNF TNFRSF11B
2 animal organ morphogenesis GO:0009887 9.77 COMP TNF TNFSF11
3 defense response to Gram-positive bacterium GO:0050830 9.73 CRP NLRP3 TNF
4 positive regulation of JNK cascade GO:0046330 9.71 TNF TNFSF11 TRPV4
5 tumor necrosis factor-mediated signaling pathway GO:0033209 9.67 TNF TNFRSF11B TNFSF11
6 skeletal system development GO:0001501 9.67 ACAN ANKH COMP TNFRSF11B
7 immune response GO:0006955 9.65 B2M MICA PRG4 TNF TNFSF11
8 blood coagulation, intrinsic pathway GO:0007597 9.58 F8 F9
9 regulation of osteoclast differentiation GO:0045670 9.57 TNF TNFSF11
10 growth plate cartilage development GO:0003417 9.52 COMP ZMPSTE24
11 negative regulation of lipid storage GO:0010888 9.51 CRP TNF
12 acute-phase response GO:0006953 9.5 CRP F8 HFE
13 cellular response to iron ion GO:0071281 9.46 B2M HFE
14 negative regulation of receptor binding GO:1900121 9.43 B2M HFE
15 positive regulation of receptor binding GO:1900122 9.4 B2M HFE
16 T cell mediated cytotoxicity GO:0001913 9.28 MICA
17 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.25 MICA
18 positive regulation of ferrous iron binding GO:1904434 9.16 B2M HFE
19 positive regulation of gene expression GO:0010628 9.1 CRP HFE TNF TNFSF11 TRPV4 ZMPSTE24
20 positive regulation of transferrin receptor binding GO:1904437 8.96 B2M HFE

Molecular functions related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.8 B2M CRP HGD NLRP3 TNF TRPV4
2 extracellular matrix structural constituent conferring compression resistance GO:0030021 9.26 ACAN PRG4
3 natural killer cell lectin-like receptor binding GO:0046703 8.65 MICA
4 beta-2-microglobulin binding GO:0030881 8.62 HFE MICA
5 protein binding GO:0005515 10.06 ACAN B2M COMP CRP F8 F9

Sources for Arthropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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