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MCID: ART023
MIFTS: 67

Arthropathy

Categories: Bone diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Arthropathy

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MalaCards integrated aliases for Arthropathy:

Name: Arthropathy 12 29 55 15 73
Joint Ankylosis of the Pelvic Region and Thigh 12
Ankylosis of Joint of Pelvic Region and Thigh 12
Joint Ankylosis of the Ankle and/or Foot 12
Ankylosis of Joint of Ankle and/or Foot 12
Joint Ankylosis of the Shoulder Region 12
Ankylosis of Joint of Shoulder Region 12
Joint Ankylosis of the Ankle and Foot 12
Arthropathy Associated with Infection 73
Ankylosis of Joint of Multiple Sites 12
Ankylosis of Ankle and Foot Joint 12
Joint Ankylosis of the Lower Leg 12
Joint Ankylosis of the Upper Arm 12
Ankylosis of Joint of Lower Leg 12
Ankylosis of Joint of Upper Arm 12
Joint Ankylosis of the Forearm 12
Ankylosis of Joint of Forearm 12
Ankylosis of Lower Leg Joint 12
Ankylosis of Multiple Joints 12
Ankylosis of Upper Arm Joint 12
Joint Ankylosis of the Hand 12
Ankylosis of Forearm Joint 12
Ankylosis of Joint of Hand 12
Ankylosis of Hand Joint 12
Infectious Arthropathy 12
Joint Diseases 44

Classifications:

MalaCards categories:
Anatomical: Bone diseases
See all MalaCards categories (disease lists)
ICD10: 33


Sources

Summaries for Arthropathy

About this section
Disease Ontology : 12 A bone inflammation disease that is located in joint.

MalaCards based summary : Arthropathy, also known as joint ankylosis of the pelvic region and thigh, is related to reactive arthritis and hemophilic arthropathy, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthropathy is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Overview of nanoparticle effects and Transcription_Role of VDR in regulation of genes involved in osteoporosis. The drugs Etanercept and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include joint, bone and testes, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia : 76 An arthropathy is a disease of a joint. Arthritis is a form of arthropathy that involves inflammation of... more...

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Related Diseases for Arthropathy

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Diseases in the Arthropathy family:

Transient Arthropathy

Diseases related to Arthropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 310)
# Related Disease Score Top Affiliating Genes
1 reactive arthritis 32.8 COMP CRP TNF
2 hemophilic arthropathy 32.1 COMP HFE TNFRSF11B TNFSF11
3 pericarditis 30.8 CRP PRG4 TNF
4 psoriatic arthritis 30.5 COMP CRP MICA TNF TNFRSF11B TNFSF11
5 multicentric reticulohistiocytosis 30.3 TNFRSF11B TNFSF11
6 chondrocalcinosis 30.2 ANKH HFE TNFRSF11B
7 spondylitis 30.1 CRP MICA TNF
8 spondylarthropathy 30.0 B2M TNF
9 rheumatic disease 29.5 CRP TNF TNFRSF11B
10 spondyloarthropathy 1 29.4 ANKH CRP TNF TNFRSF11B
11 arthritis 29.4 ACAN ANKH MICA TNF TNFSF11
12 celiac disease 1 29.3 HFE MICA TNF
13 chronic meningitis 29.1 CRP NLRP3
14 meningitis 29.1 CRP NLRP3 TNF
15 rheumatoid arthritis 28.3 COMP CRP TNF TNFRSF11B TNFSF11
16 myeloma, multiple 28.2 B2M CRP TNF TNFRSF11B TNFSF11
17 synovitis 27.9 COMP CRP PRG4 TNF TNFRSF11B TNFSF11
18 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.5
19 multicentric osteolysis, nodulosis, and arthropathy 12.4
20 crystal arthropathies 12.4
21 digital arthropathy-brachydactyly, familial 12.3
22 arthropathy, progressive pseudorheumatoid, of childhood 12.3
23 neurogenic arthropathy 12.2
24 mseleni joint disease 12.2
25 behcet's syndrome arthropathy 12.0
26 handigodu joint disease 12.0
27 transient arthropathy 12.0
28 arthropathy, erosive 11.9
29 multicentric osteolysis-nodulosis-arthropathy spectrum 11.8
30 progeria-associated arthropathy 11.8
31 chondrocalcinosis 2 11.8
32 familial calcium pyrophosphate deposition 11.6
33 gout 11.4
34 osteoarthritis 11.3
35 distal arthrogryposis 11.2
36 ankylosis 11.1
37 myhre syndrome 11.1
38 winchester syndrome 11.0
39 hemochromatosis, type 2a 11.0
40 mitochondrial dna depletion syndrome 6 10.9
41 mpv17-related hepatocerebral mitochondrial dna depletion syndrome 10.9
42 atransferrinemia 10.8
43 xanthinuria, type i 10.8
44 chondrocalcinosis 1 10.8
45 xanthinuria, type ii 10.8
46 cinca syndrome 10.8
47 spondyloepiphyseal dysplasia, kimberley type 10.8
48 czech dysplasia 10.8
49 hemochromatosis, type 2b 10.8
50 hemochromatosis type 2 10.8

Graphical network of the top 20 diseases related to Arthropathy:



Diseases related to Arthropathy
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Symptoms & Phenotypes for Arthropathy

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UMLS symptoms related to Arthropathy:


arthralgia, back pain, metatarsalgia, muscle cramp, sciatica, other symptoms referable to joint, other symptoms referable to joint, shoulder region, other symptoms referable to joint, upper arm, other symptoms referable to joint, forearm, other symptoms referable to joint, hand, other symptoms referable to joint, pelvic region and thigh, other symptoms referable to joint, lower leg, other symptoms referable to joint, ankle and foot, other symptoms referable to joint, other specified sites, other symptoms referable to joint, multiple sites, joint stiffness, musculoskeletal symptom, other symptoms referable to joint, site unspecified, joint symptom, stiffness of joint, not elsewhere classified in icd10cm

MGI Mouse Phenotypes related to Arthropathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 NLRP3 TNF TNFSF11 TRPV4 ZMPSTE24 ANKH
2 growth/size/body region MP:0005378 10.17 ANKH B2M COMP HFE HGD MMP2
3 immune system MP:0005387 10.17 ANKH B2M COMP CRP F8 F9
4 cardiovascular system MP:0005385 10.16 F9 MMP2 TNF TNFRSF11B TRPV4 ANKH
5 hematopoietic system MP:0005397 10.14 ANKH B2M F8 F9 HFE MMP2
6 limbs/digits/tail MP:0005371 9.86 ANKH COMP HFE NLRP3 TNF TNFRSF11B
7 liver/biliary system MP:0005370 9.7 B2M F9 HFE HGD NLRP3 TNF
8 muscle MP:0005369 9.5 COMP MMP2 TNF TNFSF11 TRPV4 ZMPSTE24
9 skeleton MP:0005390 9.28 ANKH COMP HGD MMP2 NLRP3 TNF
Sources

Drugs & Therapeutics for Arthropathy

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Drugs for Arthropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 917)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 185243-69-0
2
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 9004-61-9 53477741
3
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
4
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
5
Thrombin Approved, Investigational Phase 4,Not Applicable
6
Bevacizumab Approved, Investigational Phase 4 216974-75-3
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
8
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-84-3 187
9
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
10
Menthol Approved Phase 4,Phase 3,Phase 2,Not Applicable 2216-51-5 16666
11
Iron Approved Phase 4,Phase 1,Phase 2 7439-89-6 23925
12
Rivaroxaban Approved Phase 4,Phase 2,Phase 3,Not Applicable 366789-02-8
13
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
14
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
15
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 169590-42-5 2662
16
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 1 161796-78-7, 119141-88-7 4594 9579578
17
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22204-53-1 1302 156391
18
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 2180-92-9, 38396-39-3 2474
19
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
20
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
21
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Not Applicable 84057-95-4 71273 175805
22
Cimetidine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 51481-61-9 2756
23
Hyoscyamine Approved Phase 4 101-31-5 64692
24
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
25
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 51-41-2 439260
26
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1959-05-2, 59-05-2 126941
27
Tacrolimus Approved, Investigational Phase 4,Phase 3 104987-11-3 445643 439492
28
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2,Not Applicable 118-42-3 3652
29
Sulfasalazine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 599-79-1 5353980 5359476
30
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75706-12-6 3899
31
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
32
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
33
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 15307-86-5 3033
34
Etoricoxib Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 202409-33-4 123619
35
Abatacept Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 332348-12-6 10237
36
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 174722-31-7 10201696
37
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83-43-2 6741
38
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 16590-41-3 5360515
39
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
40
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
41
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
42
Ketorolac Approved Phase 4,Phase 3,Phase 2,Not Applicable 74103-06-3, 66635-83-4 3826
43
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 57-27-2 5288826
44
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
45
Calcium Carbonate Approved, Investigational Phase 4,Phase 3,Phase 2 471-34-1
46
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 50-18-0, 6055-19-2 2907
47
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 22916-47-8 4189
48
Clonidine Approved Phase 4,Not Applicable 4205-90-7 2803
49
Pamidronate Approved Phase 4 40391-99-9 4674
50
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337

Interventional clinical trials:

(show top 50) (show all 7057)
# Name Status NCT ID Phase Drugs
1 Targeting Synovitis in Early Rheumatoid Arthritis Unknown status NCT00920478 Phase 4
2 Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis Unknown status NCT00144820 Phase 4 Injection of Hyaluronan or Saline
3 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
4 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
5 Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens Unknown status NCT02314325 Phase 4 ADVATE [Antihemophilic Factor (Recombinant)];ADVATE [Antihemophilic Factor (Recombinant)]
6 Birmingham Hip Resurfacing (BHR) Study: Implantation of a Hip Resurfacing Endoprosthesis Unknown status NCT00180206 Phase 4
7 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4 Human Fibrinogen and human thrombin (Evicel);Sodium Chlorure (Physiological saline)
8 Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic Synovitis Unknown status NCT02060305 Phase 4 Bevacizumab intra-articular injection
9 Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection Unknown status NCT02835521 Phase 4 Joint injection with triamcinolone hexacetonide
10 Safety and Efficacy of Intra-articular Ozone Injections for Knee Osteoarthritis Unknown status NCT02833545 Phase 4
11 Intra-articular Botox Type A Versus Corticosteroids in Knee Osteoarthritis Unknown status NCT02829281 Phase 4 Botulinum Toxin Type A;Triamcinolone hexacetonide;Saline
12 Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN Unknown status NCT02821468 Phase 4 Droglican;Paracetamol or oral NSAIDs excluding COX2 inhibitors
13 Assessment of a Knee Brace in Patients With Osteoarthritis Unknown status NCT02706106 Phase 4
14 Effectiveness of Trapeziometacarpal Splint Unknown status NCT02635932 Phase 4
15 Effects of Hyaluronic Acid vs. Hyaluronic Acid on Knee Osteoarthritis Unknown status NCT02625727 Phase 4
16 Intravenous Iron Sucrose in Arthroplasty Unknown status NCT02544828 Phase 4 Iron Sucrose 200mg;placebo
17 Does Intraoperative Intravenous Iron Enhance Postoperative Oxygenation Profile in Total Knee Arthroplasty Surgery? Unknown status NCT02544464 Phase 4 ferric carboxymaltose 1000 mg;placebo
18 The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy Unknown status NCT02539069 Phase 4
19 The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) Unknown status NCT02539056 Phase 4
20 Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis Unknown status NCT02484508 Phase 4 Guli capsule;Kangguzengsheng capsule
21 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
22 Validation of a Stress Device for the Knee Unknown status NCT02444663 Phase 4
23 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
24 Medical Chitosan or Sodium Hyaluronate for Knee Osteoarthritis (CHOOSE) Unknown status NCT02323451 Phase 4 Sodium Hyaluronate Injection
25 Tranexamic Acid in Knee Joint Surgery Unknown status NCT02278263 Phase 4 Tranexamic Acid;Normal saline (0.9% NaCl)
26 Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty Unknown status NCT02152917 Phase 4 Tranexamic acid;Floseal®
27 Intraarticular Xylitol Injections for Knee Osteoarthritis Unknown status NCT02104596 Phase 4
28 Daily Activity and Gait Analysis After Viscosupplement Injection Among Hip Osteoarthritis Patients Unknown status NCT02086474 Phase 4 Hyaluronan;Bupivacaine
29 The Effect of Spironolactone on Pain in Older People With Osteoarthritis Unknown status NCT02046668 Phase 4 spironolactone
30 Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy Unknown status NCT02000297 Phase 4
31 A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis Unknown status NCT01985165 Phase 4 Imrecoxib
32 Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR) Unknown status NCT01973530 Phase 4
33 Reinflation After Early Tourniquet Release in Total Knee Arthroplasty Unknown status NCT01832272 Phase 4
34 Hip Viscosupplementation: What is the Best Dosage? Unknown status NCT01810809 Phase 4 1 ampoule of Hylan GF-20;2 ampoules of Hylan GF-20;3 ampoules of Hylan GF-20
35 Bone Forming at Prosthetic Surfaces. Fingerprint2 Unknown status NCT01623687 Phase 4
36 RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem Unknown status NCT01618084 Phase 4
37 Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis Unknown status NCT01329406 Phase 4 Milnacipran;Placebo
38 Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Unknown status NCT01233739 Phase 4 Chondroitin sulfate;Placebo
39 Assessment of the Effects of Chondroitin Sulphate in Patients With Knee Osteoarthritis With Functional Magnetic Resonance Imaging (fMRI) Unknown status NCT01226615 Phase 4 Chondroitin sulphate (Condrosan®);Placebo
40 Prophecy Guide Outcomes in Total Knee Replacement Surgery Unknown status NCT01163708 Phase 4
41 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
42 Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty Unknown status NCT01027819 Phase 4
43 The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics Unknown status NCT00778076 Phase 4
44 Use of Cold and Compression Therapy With Total Knee Replacement Patients Unknown status NCT00712816 Phase 4
45 Trial Comparing Navigated and Conventional Implantation Techniques in Knee Replacement Surgery Unknown status NCT00431509 Phase 4
46 The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Unknown status NCT00422643 Phase 4 Sodium hyaluronate (hyaluronic acid)
47 Effectiveness Study of Hylan G-F 20 to Preserve Cartilage in Osteoarthritis of the Knee Unknown status NCT00393393 Phase 4 intra-articular injection of Hylan G-F 20
48 Effect of Flex-a-New on Osteoarthritis of the Knee Unknown status NCT00294801 Phase 4 flex-a-new (food supplement)
49 Comparing Clinical Outcome of 2 Different Total Knee Prostheses: Nexgen LPS-Flex Versus AGC Unknown status NCT00294528 Phase 4
50 Efficacy of Celecoxib Vs Placebo to Prevent Pain in a Paced Walk Unknown status NCT00194090 Phase 4 celecoxib

Search NIH Clinical Center for Arthropathy

Cochrane evidence based reviews: joint diseases

Sources

Genetic Tests for Arthropathy

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Genetic tests related to Arthropathy:

# Genetic test Affiliating Genes
1 Arthropathy 29
Sources

Anatomical Context for Arthropathy

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The Foundational Model of Anatomy Ontology organs/tissues related to Arthropathy:

19
Joint

MalaCards organs/tissues related to Arthropathy:

41
Bone, Testes, Eye, Bone Marrow, Breast, Heart, Endothelial
Sources

Publications for Arthropathy

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Articles related to Arthropathy:

(show top 50) (show all 1034)
# Title Authors Year
1
Postural control during a transition task in haemophilic children, adolescents and young adults with haemophilic ankle arthropathy. ( 29673013 )
2018
2
Mid-term outcomes of routine proximal row carpectomy compared with proximal row carpectomy with dorsal capsular interposition arthroplasty for the treatment of late-stage arthropathy of the wrist. ( 29437062 )
2018
3
Range of motion after total knee arthroplasty in hemophilic arthropathy. ( 29788949 )
2018
4
Safety of intra-articular transplantation of lentivirally transduced mesenchymal stromal cells for haemophilic arthropathy in a non-human primate. ( 29737459 )
2018
5
Primary Total Hip Arthroplasty for Charcot Arthropathy is Associated With High Complications but Improved Clinical Outcomes. ( 29706256 )
2018
6
Dynamic contrast-enhanced magnetic resonance imaging for differentiating osteomyelitis from acute neuropathic arthropathy in the complicated diabetic foot. ( 29654348 )
2018
7
Acute locked superior shoulder dislocation in a patient with cuff tear arthropathy. ( 29930172 )
2018
8
Erosive Gouty Arthropathy Resulting in a Telescoping Digit. ( 29794875 )
2018
9
Advanced Hemophilic Arthropathy: Sensitivity of Soft Tissue Discrimination With Musculoskeletal Ultrasound. ( 29363781 )
2018
10
Diabetic foot syndrome: Charcot arthropathy or osteomyelitis? Part I: Clinical picture and radiography. ( 29844940 )
2018
11
Synovectomy using Samarium-153 Hydroxyapatite in the Elbows and Ankles of Patients with Hemophilic Arthropathy. ( 29398959 )
2018
12
Safety and effectiveness of fascial therapy in adult patients with hemophilic arthropathy. A pilot study. ( 29334292 )
2018
13
Joint lavage followed by intra-articular injection of hyaluronic acid and/or corticosteroids in patients with severe hemophilic arthropathy of the knee: Is this intervention really effective? ( 29722575 )
2018
14
Association of CXCL13 serum level and ultrasonographic findings of joints in patients with systemic lupus erythematosus and Jaccoud's arthropathy. ( 29338586 )
2018
15
Clinical and Radiological Evaluation After Chemical Synovectomy With Rifampicin in Hemophilic Arthropathy: Korean Experience With a 2-Week Interval Protocol. ( 29961743 )
2018
16
Safety of fascial therapy in adult patients with hemophilic arthropathy of ankle. A cohort study. ( 29550698 )
2018
17
Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome. ( 29397575 )
2018
18
Advanced Imaging in the Diagnosis of Gout and Other Crystal Arthropathies. ( 29672810 )
2018
19
Management of autonomic dysreflexia associated with Charcot spinal arthropathy in a patient with complete spinal cord injury: Case report and review of the literature. ( 29930879 )
2018
20
Risk and risk factors for revision after primary reverse shoulder arthroplasty for cuff tear arthropathy and osteoarthritis: a Nordic Arthroplasty Register Association study. ( 29779980 )
2018
21
Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. ( 29922458 )
2018
22
Syringomyelia with left knee charcot arthropathy: a case report. ( 29405778 )
2018
23
Missing angiogenic factors in hemophilic arthropathy. ( 29103337 )
2018
24
Arthroscopic soft-tissue interposition arthroplasty of the glenohumeral joint for ochronotic arthropathy: A case report. ( 29361375 )
2018
25
Imaging of Progressive Neuropathic Arthropathy of The Shoulder. ( 29979203 )
2018
26
Charcot spinal arthropathy. ( 29755231 )
2018
27
Primary Total Knee Arthroplasty in Patients With Neuropathic (Charcot) Arthropathy: Contemporary Results. ( 29706257 )
2018
28
Autoimmune temporomandibular arthropathy: diagnostic considerations. ( 29964250 )
2018
29
Radiological features of crystal-induced arthropathy associated with hereditary hemochromatosis with homozygous C282Y mutation. ( 29731342 )
2018
30
Simultaneous bilateral total knee arthroplasty in patients with end-stage hemophilic arthropathy: a mean follow-up of 6 years. ( 29371670 )
2018
31
Neuropathic Arthropathy of the Glenohumeral Joint A Review of the Literature. ( 29799367 )
2018
32
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNFI+ pathway. ( 29776906 )
2018
33
Quantification of physical activity in adult patients with haemophilic arthropathy in prophylaxis treatment using a fitness tracker. ( 29271553 )
2018
34
Response to: missing angiogenic factors in hemophilic arthropathy. ( 29092644 )
2018
35
Sensory strategies of postural sway during quiet stance in patients with haemophilic arthropathy. ( 28722821 )
2017
36
Functional pedal construct achieved by combined operative treatment in peritalar complex Charcot arthropathy: A prospective study of 38 feet. ( 29409253 )
2017
37
Familial digital arthropathy-brachydactyly, familial: An infrequent cause of joint deformity in the adolescents. ( 28755822 )
2017
38
Fresh Osteochondral Allograft Transplantation for Focal Chondral Defect of the Humerus Associated With Anchor Arthropathy and Failed SLAP Repair. ( 29354455 )
2017
39
Arthroscopic debridement for advanced haemophilic ankle arthropathy. ( 28782247 )
2017
40
Musculoskeletal Disease in MDA5-Related Type I Interferonopathy: A Mendelian Mimic of Jaccoud's Arthropathy. ( 28605144 )
2017
41
Reverse Total Shoulder Arthroplasty as Treatment for Rotator Cuff-Tear Arthropathy and Shoulder Dislocations in an Elderly Male with Parkinson's Disease. ( 28948058 )
2017
42
Management of Hemophilic Arthropathy of the Ankle. ( 28891453 )
2017
43
Effect of radiosynoviorthesis on the progression of arthropathy and haemarthrosis reduction in haemophilic patients. ( 28891593 )
2017
44
Ultrasound for Early Detection of Joint Disease in Patients with Hemophilic Arthropathy. ( 28758960 )
2017
45
Comment on: Hereditary haemochromatosis arthropathy and Doppler ultrasound findings of synovitis: reply. ( 29228396 )
2017
46
Hereditary hemochromatosis arthropathy and Doppler ultrasound findings of synovitis. ( 28371912 )
2017
47
Advanced MR Imaging Techniques for Differentiation of Neuropathic Arthropathy and Osteomyelitis in the Diabetic Foot. ( 28696850 )
2017
48
Sonographic Findings of Hands and Wrists in Systemic Lupus Erythematosus Patients With Jaccoud Arthropathy. ( 29200021 )
2017
49
Flip or Flop: Post-Traumatic Charcot Arthropathy of the Right Hip from Acrobatics. ( 28832382 )
2017
50
Jaccoud's arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment. ( 28776364 )
2017
Sources

Variations for Arthropathy

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Expression for Arthropathy

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Search GEO for disease gene expression data for Arthropathy.
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Pathways for Arthropathy

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Pathways related to Arthropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Overview of nanoparticle effects 1
10.54 CRP TNF
2
Transcription_Role of VDR in regulation of genes involved in osteoporosis 22
10.45 TNF TNFRSF11B TNFSF11
3
Osteoclast Signaling 1
10.36 TNFRSF11B TNFSF11
4
Osteoblast Signaling 1
10.1 TNFRSF11B TNFSF11
Sources

GO Terms for Arthropathy

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Cellular components related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.91 ANKH HFE MICA TNF TNFRSF11B TNFSF11
2 extracellular region GO:0005576 9.77 ACAN B2M COMP CRP F8 F9
3 extracellular matrix GO:0031012 9.62 ACAN COMP MMP2 PRG4
4 extracellular space GO:0005615 9.4 B2M COMP CRP F8 F9 HFE
5 MHC class I protein complex GO:0042612 9.26 B2M HFE
6 HFE-transferrin receptor complex GO:1990712 9.16 B2M HFE

Biological processes related to Arthropathy according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.91 B2M PRG4 TNF TNFRSF11B TNFSF11
2 extracellular matrix organization GO:0030198 9.76 ACAN COMP TNF TNFRSF11B
3 defense response to Gram-positive bacterium GO:0050830 9.7 CRP NLRP3 TNF
4 positive regulation of JNK cascade GO:0046330 9.67 TNF TNFSF11 TRPV4
5 skeletal system development GO:0001501 9.62 ACAN ANKH COMP TNFRSF11B
6 blood coagulation, intrinsic pathway GO:0007597 9.55 F8 F9
7 regulation of osteoclast differentiation GO:0045670 9.54 TNF TNFSF11
8 negative regulation of lipid storage GO:0010888 9.48 CRP TNF
9 cellular response to iron ion GO:0071281 9.43 B2M HFE
10 acute-phase response GO:0006953 9.43 CRP F8 HFE
11 negative regulation of receptor binding GO:1900121 9.4 B2M HFE
12 positive regulation of receptor binding GO:1900122 9.37 B2M HFE
13 regulation of iron ion import GO:1900390 9.16 B2M HFE
14 positive regulation of ferrous iron binding GO:1904434 8.96 B2M HFE
15 positive regulation of transferrin receptor binding GO:1904437 8.62 B2M HFE

Molecular functions related to Arthropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 B2M CRP HGD NLRP3 TNF TRPV4
2 beta-2-microglobulin binding GO:0030881 8.62 HFE MICA
Sources

Sources for Arthropathy

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
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31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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37 KEGG
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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