MCID: ASB003
MIFTS: 26

Asbestos Intoxication

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Asbestos Intoxication

MalaCards integrated aliases for Asbestos Intoxication:

Name: Asbestos Intoxication 58
Asbestosis 58 71

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

ICD10 via Orphanet 33 J61
UMLS via Orphanet 72 C0003949
Orphanet 58 ORPHA2302
UMLS 71 C0003949

Summaries for Asbestos Intoxication

MalaCards based summary : Asbestos Intoxication, also known as asbestosis, is related to asbestosis and anthracosis. The drugs Artichoke and Nintedanib have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and neutrophil.

Related Diseases for Asbestos Intoxication

Diseases related to Asbestos Intoxication via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 asbestosis 12.8
2 anthracosis 11.7
3 interstitial lung disease 11.6
4 benign mesothelioma 10.9
5 silicosis 10.8
6 pneumoconiosis 10.7
7 pulmonary fibrosis 10.7
8 lung cancer 10.6
9 lung disease 10.6
10 mesothelioma, malignant 10.5
11 fibrosis of extraocular muscles, congenital, 1 10.5
12 pleural disease 10.5
13 pulmonary fibrosis, idiopathic 10.4
14 peritoneal mesothelioma 10.4
15 bronchitis 10.4
16 sarcoidosis 1 10.3
17 pulmonary tuberculosis 10.3
18 malignant pleural mesothelioma 10.3
19 pleurisy 10.2
20 adenocarcinoma 10.2
21 labrador lung 10.2
22 respiratory failure 10.2
23 diffuse pulmonary fibrosis 10.2
24 peripheral nervous system disease 10.2
25 neuropathy 10.2
26 mycobacterium tuberculosis 1 10.1
27 gastric cancer 10.1
28 aspergillosis 10.1
29 berylliosis 10.1
30 larynx cancer 10.1
31 glomerulonephritis 10.1
32 bronchiolitis 10.1
33 pneumonia 10.1
34 autoimmune disease 10.0
35 myeloma, multiple 10.0
36 lung cancer susceptibility 3 10.0
37 small cell carcinoma 10.0
38 pericarditis 10.0
39 systemic scleroderma 10.0
40 pleural cancer 10.0
41 extrinsic allergic alveolitis 10.0
42 bronchiectasis 10.0
43 47,xyy 10.0
44 back pain 10.0
45 colorectal cancer 9.9
46 systemic lupus erythematosus 9.9
47 neutrophil migration 9.9
48 ovarian cancer 9.9
49 pulmonary hypertension, primary, 1 9.9
50 small cell cancer of the lung 9.9

Graphical network of the top 20 diseases related to Asbestos Intoxication:



Diseases related to Asbestos Intoxication

Symptoms & Phenotypes for Asbestos Intoxication

Drugs & Therapeutics for Asbestos Intoxication

Drugs for Asbestos Intoxication (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Artichoke Approved Phase 2
2
Nintedanib Approved Phase 2 656247-17-5 56843413
3 Xenon Experimental Early Phase 1 7440-63-3
4 Respiratory System Agents

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Comparison of the Ultra-low-dose Veo Algorithm With the Gold Standard Filtered Back Projection for Detecting Pulmonary Asbestos-related Conditions Completed NCT01955018 Phase 4
2 Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease Recruiting NCT03241420 Phase 3
3 Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population (The ABOCA Phase II Trial) Recruiting NCT02076672 Phase 2 Artichoke WPC
4 The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial Not yet recruiting NCT04161014 Phase 2 Nintedanib 150 MG [Ofev]
5 OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis Unknown status NCT02280343
6 Idiopathic Pulmonary Fibrosis Job Exposures Study Completed NCT03211507
7 Linkage Study in Familial Pulmonary Fibrosis Completed NCT00016627
8 Specialized Center of Research in Occupational and Immunologic Lung Disease Completed NCT00005280
9 Molecular Epidemiology of Acute Respiratory Distress Syndrome Recruiting NCT00006496
10 The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study Enrolling by invitation NCT04016181
11 Developing Optimal Parameters for Hyperpolarized Noble Gas (3He and 129Xe) and Inert Fluorinated Gas Magnetic Resonance Imaging of Lung Disorders Not yet recruiting NCT02748798 Early Phase 1 HP 3He;HP 129Xe;PFP;SF6
12 It's Not JUST Idiopathic Pulmonary Fibrosis Study Suspended NCT03670576

Search NIH Clinical Center for Asbestos Intoxication

Genetic Tests for Asbestos Intoxication

Anatomical Context for Asbestos Intoxication

MalaCards organs/tissues related to Asbestos Intoxication:

40
Lung, Testes, Neutrophil, Lymph Node, Heart, T Cells, Nk Cells

Publications for Asbestos Intoxication

Articles related to Asbestos Intoxication:

(show top 50) (show all 2266)
# Title Authors PMID Year
1
Asbestos-related diseases. 61
32553000 2020
2
Trends in Pneumoconiosis Deaths - United States, 1999-2018. 61
32525855 2020
3
Trends in global, regional and national incidence of pneumoconiosis caused by different aetiologies: an analysis from the Global Burden of Disease Study 2017. 61
32188634 2020
4
Increasing incidence of asbestosis worldwide, 1990-2017: results from the Global Burden of Disease study 2017. 61
32467338 2020
5
[Sustainability in Outpatient Pulmonary Rehabilitation in Patients with Asbestosis - Results of an 8-Year Follow Up]. 61
32053838 2020
6
Factors Affecting Asbestosis Mortality Among Asbestos-Cement Workers in Italy. 61
32328661 2020
7
Prognosis and causes of death of patients with acute exacerbation of fibrosing interstitial lung diseases. 61
32265195 2020
8
A Case of Autoimmune Pulmonary Alveolar Proteinosis with Pulmonary Fibrosis and Asbestosis-Like Features. 61
32336733 2020
9
The MUC5B promoter risk allele for idiopathic pulmonary fibrosis predisposes to asbestosis. 61
31949121 2020
10
The Wittenoom legacy. 61
31670764 2020
11
Familial Interstitial Lung Disease. 61
32279293 2020
12
Talc and mesothelioma: mineral fiber analysis of 65 cases with clinicopathological correlation. 61
32183579 2020
13
[Diagnostic Challenges of Mixed Dust Silicosis (Mixed Dust Pneumoconiosis) - 5 Case Reports]. 61
32052391 2020
14
Malignant Diffuse Mesothelioma in Women: A Study of 354 Cases. 61
31876584 2020
15
Mortality and mesothelioma incidence among chrysotile asbestos miners in Balangero, Italy: A cohort study. 61
31821579 2020
16
[Diffuse Intraparenchymal Mesothelioma: An Atypical Presentation]. 61
32035500 2020
17
Pleural Plaques and the Risk of Lung Cancer in Asbestos-exposed Subjects. 61
31433952 2020
18
NLRP3 and CARD8 polymorphisms influence risk for asbestos-related diseases. 61
32549782 2020
19
Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study. 61
31714372 2020
20
A case of hypersensitivity pneumonitis in a worker exposed to terephthalic acid in the production of polyethylene terephthalate. 61
31691678 2020
21
Occurrence, behaviour, and human exposure pathways and health risks of toxic geogenic contaminants in serpentinitic ultramafic geological environments (SUGEs): A medical geology perspective. 61
31693951 2020
22
[About the asbestos and the Position Paper on asbestos of the Italian Society of Occupational Medicine]. 61
32374117 2020
23
Analytical transmission electron microscopy of amosite asbestos from South Africa. 61
30702033 2020
24
Global use of asbestos - legitimate and illegitimate issues. 61
32549902 2020
25
Asbestos, Smoking and Lung Cancer: An Update. 61
31905913 2019
26
[Incidence and yrend of occupational pneumoconiosis in Ankang city from 1974 to 2017]. 61
31937033 2019
27
[The occurrence of asbestos-related diseases among former employees of asbestos processing plants in Poland]. 61
31682242 2019
28
Position Paper on Asbestos of the Italian Society of Occupational Medicine. 61
31846450 2019
29
[Idiopathic pleuroparenehymal fibroelastosis: report of one case and review of literature]. 61
31694096 2019
30
Pneumatosis intestinalis and pneumoretroperitoneum post steroid use in a patient with superior mesenteric artery syndrome. 61
31262624 2019
31
Asbestosis and silicosis hospitalizations in Italy (2001-2015): results from the National Hospital Discharge Registry. 61
30753424 2019
32
Relationship between pleural plaques and biomarkers of cumulative asbestos dose. A necropsy study. 61
31659992 2019
33
Bronchoalveolar cell differential count and the number of asbestos bodies correlate with survival in patients with asbestosis. 61
31331950 2019
34
Mortality of older construction and craft workers employed at department of energy nuclear sites: Follow-up through 2016. 61
31380577 2019
35
In vivo probe-based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT. 61
30811085 2019
36
NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis. 61
31434799 2019
37
On the diagnosis of malignant pleural mesothelioma: A necropsy-based study of 171 cases (1997-2016). 61
29714657 2019
38
Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy. 61
31391078 2019
39
The natural course of lung function decline in asbestos exposed subjects with pleural plaques and asbestosis. 61
31226624 2019
40
Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice. 61
31022494 2019
41
[Asbestos and its effects on health of Icelanders - review]. 61
31411568 2019
42
Mesothelioma mortality within two radiation monitored occupational cohorts. 61
31290725 2019
43
High frequency and severity of pleural changes in former workers exposed to anthophyllite associated with other contaminating amphibole asbestos in Brazil. 61
31046142 2019
44
Oxidative effects of lungs in Wistar rats caused by long-term exposure to four kinds of China representative chrysotile. 61
31055741 2019
45
Monitoring of airborne asbestos fibers in an urban ambient air of Shahryar City, Iran: levels, spatial distribution, seasonal variations, and health risk assessment. 61
30623323 2019
46
Imaging in idiopathic pulmonary fibrosis: diagnosis and mimics. 61
30726312 2019
47
Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event. 61
30609805 2019
48
Interstitial Lung Diseases in Developing Countries. 61
30741505 2019
49
The Its Not JUST Idiopathic pulmonary fibrosis Study (INJUSTIS): description of the protocol for a multicentre prospective observational cohort study identifying biomarkers of progressive fibrotic lung disease. 61
31258922 2019
50
Transbronchial lung cryobiopsy: a novel confirmatory tool to diagnose asbestos-related pulmonary fibrosis. 61
30455954 2019

Variations for Asbestos Intoxication

Expression for Asbestos Intoxication

Search GEO for disease gene expression data for Asbestos Intoxication.

Pathways for Asbestos Intoxication

GO Terms for Asbestos Intoxication

Sources for Asbestos Intoxication

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....