MCID: ASB003
MIFTS: 26

Asbestos Intoxication

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Asbestos Intoxication

MalaCards integrated aliases for Asbestos Intoxication:

Name: Asbestos Intoxication 58
Asbestosis 58 71

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

ICD10 via Orphanet 33 J61
UMLS via Orphanet 72 C0003949
Orphanet 58 ORPHA2302
UMLS 71 C0003949

Summaries for Asbestos Intoxication

MalaCards based summary : Asbestos Intoxication, also known as asbestosis, is related to asbestosis and anthracosis. The drugs Artichoke and Nintedanib have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and testes.

Related Diseases for Asbestos Intoxication

Diseases related to Asbestos Intoxication via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
# Related Disease Score Top Affiliating Genes
1 asbestosis 12.8
2 anthracosis 11.7
3 interstitial lung disease 11.6
4 benign mesothelioma 10.9
5 silicosis 10.8
6 pneumoconiosis 10.7
7 idiopathic interstitial pneumonia 10.7
8 pulmonary fibrosis 10.7
9 lung disease 10.6
10 lung cancer 10.6
11 mesothelioma, malignant 10.5
12 pleural disease 10.5
13 pulmonary fibrosis, idiopathic 10.4
14 peritoneal mesothelioma 10.4
15 fibrosis of extraocular muscles, congenital, 1 10.4
16 bronchitis 10.4
17 sarcoidosis 1 10.3
18 pulmonary tuberculosis 10.3
19 malignant pleural mesothelioma 10.3
20 pleurisy 10.2
21 labrador lung 10.2
22 respiratory failure 10.2
23 adenocarcinoma 10.2
24 diffuse pulmonary fibrosis 10.2
25 peripheral nervous system disease 10.2
26 neuropathy 10.2
27 mycobacterium tuberculosis 1 10.1
28 gastric cancer 10.1
29 aspergillosis 10.1
30 berylliosis 10.1
31 larynx cancer 10.1
32 glomerulonephritis 10.1
33 bronchiolitis 10.1
34 pneumonia 10.1
35 autoimmune disease 10.0
36 myeloma, multiple 10.0
37 lung cancer susceptibility 3 10.0
38 small cell carcinoma 10.0
39 pericarditis 10.0
40 systemic scleroderma 10.0
41 pleural cancer 10.0
42 extrinsic allergic alveolitis 10.0
43 bronchiectasis 10.0
44 47,xyy 10.0
45 back pain 10.0
46 colorectal cancer 9.9
47 systemic lupus erythematosus 9.9
48 neutrophil migration 9.9
49 ovarian cancer 9.9
50 pulmonary hypertension, primary, 1 9.9

Graphical network of the top 20 diseases related to Asbestos Intoxication:



Diseases related to Asbestos Intoxication

Symptoms & Phenotypes for Asbestos Intoxication

Drugs & Therapeutics for Asbestos Intoxication

Drugs for Asbestos Intoxication (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Artichoke Approved Phase 2
2
Nintedanib Approved Phase 2 656247-17-5 56843413
3 Xenon Experimental Early Phase 1 7440-63-3
4 Respiratory System Agents
5 Anesthetics Early Phase 1
6 Anesthetics, General Early Phase 1
7 Central Nervous System Depressants Early Phase 1
8 Anesthetics, Inhalation Early Phase 1

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Comparison of the Ultra-low-dose Veo Algorithm With the Gold Standard Filtered Back Projection for Detecting Pulmonary Asbestos-related Conditions Completed NCT01955018 Phase 4
2 Utility of Lung Clearance Index Score as a Noninvasive Marker of Small Airways Disease Recruiting NCT03241420 Phase 3
3 Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population (The ABOCA Phase II Trial) Recruiting NCT02076672 Phase 2 Artichoke WPC
4 The Nintedanib in Progressive Pneumoconiosis Study (NiPPS): a Collaborative NSW Treatment Trial Not yet recruiting NCT04161014 Phase 2 Nintedanib 150 MG [Ofev]
5 OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early Diagnosis Unknown status NCT02280343
6 Idiopathic Pulmonary Fibrosis Job Exposures Study Completed NCT03211507
7 Linkage Study in Familial Pulmonary Fibrosis Completed NCT00016627
8 Specialized Center of Research in Occupational and Immunologic Lung Disease Completed NCT00005280
9 It's Not JUST Idiopathic Pulmonary Fibrosis Study Recruiting NCT03670576
10 Molecular Epidemiology of Acute Respiratory Distress Syndrome Recruiting NCT00006496
11 The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study Enrolling by invitation NCT04016181
12 Developing Optimal Parameters for Hyperpolarized Noble Gas (3He and 129Xe) and Inert Fluorinated Gas Magnetic Resonance Imaging of Lung Disorders Not yet recruiting NCT02748798 Early Phase 1 HP 3He;HP 129Xe;PFP;SF6

Search NIH Clinical Center for Asbestos Intoxication

Genetic Tests for Asbestos Intoxication

Anatomical Context for Asbestos Intoxication

MalaCards organs/tissues related to Asbestos Intoxication:

40
Lung, T Cells, Testes, Neutrophil, Lymph Node, Heart, Nk Cells

Publications for Asbestos Intoxication

Articles related to Asbestos Intoxication:

(show top 50) (show all 2251)
# Title Authors PMID Year
1
Malignant Diffuse Mesothelioma in Women: A Study of 354 Cases. 61
31876584 2020
2
Mortality and mesothelioma incidence among chrysotile asbestos miners in Balangero, Italy: A cohort study. 61
31821579 2020
3
[Diffuse Intraparenchymal Mesothelioma: An Atypical Presentation]. 61
32035500 2020
4
A case of hypersensitivity pneumonitis in a worker exposed to terephthalic acid in the production of polyethylene terephthalate. 61
31691678 2020
5
Occurrence, behaviour, and human exposure pathways and health risks of toxic geogenic contaminants in serpentinitic ultramafic geological environments (SUGEs): A medical geology perspective. 61
31693951 2020
6
Analytical transmission electron microscopy of amosite asbestos from South Africa. 61
30702033 2020
7
Pleural Plaques and the Risk of Lung Cancer in Asbestos-exposed Subjects. 61
31433952 2020
8
Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study. 61
31714372 2020
9
The MUC5B promoter risk allele for idiopathic pulmonary fibrosis predisposes to asbestosis. 61
31949121 2020
10
[The occurrence of asbestos-related diseases among former employees of asbestos processing plants in Poland]. 61
31682242 2019
11
Position Paper on Asbestos of the Italian Society of Occupational Medicine. 61
31846450 2019
12
Asbestos, Smoking and Lung Cancer: An Update. 61
31905913 2019
13
[Incidence and yrend of occupational pneumoconiosis in Ankang city from 1974 to 2017]. 61
31937033 2019
14
[Idiopathic pleuroparenehymal fibroelastosis: report of one case and review of literature]. 61
31694096 2019
15
Relationship between pleural plaques and biomarkers of cumulative asbestos dose. A necropsy study. 61
31659992 2019
16
Bronchoalveolar cell differential count and the number of asbestos bodies correlate with survival in patients with asbestosis. 61
31331950 2019
17
Pneumatosis intestinalis and pneumoretroperitoneum post steroid use in a patient with superior mesenteric artery syndrome. 61
31262624 2019
18
The Wittenoom legacy. 61
31670764 2019
19
Asbestosis and silicosis hospitalizations in Italy (2001-2015): results from the National Hospital Discharge Registry. 61
30753424 2019
20
Mortality of older construction and craft workers employed at department of energy nuclear sites: Follow-up through 2016. 61
31380577 2019
21
On the diagnosis of malignant pleural mesothelioma: A necropsy-based study of 171 cases (1997-2016). 61
29714657 2019
22
Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy. 61
31391078 2019
23
In vivo probe-based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT. 61
30811085 2019
24
NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis. 61
31434799 2019
25
[Asbestos and its effects on health of Icelanders - review]. 61
31411568 2019
26
Mesothelioma mortality within two radiation monitored occupational cohorts. 61
31290725 2019
27
The natural course of lung function decline in asbestos exposed subjects with pleural plaques and asbestosis. 61
31226624 2019
28
Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice. 61
31022494 2019
29
Oxidative effects of lungs in Wistar rats caused by long-term exposure to four kinds of China representative chrysotile. 61
31055741 2019
30
High frequency and severity of pleural changes in former workers exposed to anthophyllite associated with other contaminating amphibole asbestos in Brazil. 61
31046142 2019
31
Monitoring of airborne asbestos fibers in an urban ambient air of Shahryar City, Iran: levels, spatial distribution, seasonal variations, and health risk assessment. 61
30623323 2019
32
Imaging in idiopathic pulmonary fibrosis: diagnosis and mimics. 61
30726312 2019
33
Protocol for identification of airborne asbestos fibres in the urban areas and spatio-temporal trend. 61
31667124 2019
34
Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos. 61
31239765 2019
35
An outbreak of cancer and asbestosis among former amosite-exposed subjects in Ledro Valley, Italy. From discovery to environmental cleanup. 61
30968842 2019
36
Transbronchial lung cryobiopsy: a novel confirmatory tool to diagnose asbestos-related pulmonary fibrosis. 61
30455954 2019
37
Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event. 61
30609805 2019
38
Interstitial Lung Diseases in Developing Countries. 61
30741505 2019
39
The Its Not JUST Idiopathic pulmonary fibrosis Study (INJUSTIS): description of the protocol for a multicentre prospective observational cohort study identifying biomarkers of progressive fibrotic lung disease. 61
31258922 2019
40
Outcomes after lung transplantation for patients with occupational lung diseases. 61
30506808 2019
41
[The German Mesothelioma Register : Current pathological diagnostics and services]. 61
30446780 2018
42
Impact of asbestos on public health: a retrospective study on a series of subjects with occupational and non-occupational exposure to asbestos during the activity of Fibronit plant (Broni, Italy). 61
30687679 2018
43
Dosimetry of inhaled elongate mineral particles in the respiratory tract: The impact of shape factor. 61
29738812 2018
44
Measuring EMPs in the lung what can be measured in the lung: Asbestiform minerals and cleavage fragments. 61
29959999 2018
45
Mortality among workers exposed to asbestos at the shipyard of Genoa, Italy: a 55 years follow-up. 61
30594195 2018
46
Shorter telomere length and DNA hypermethylation in peripheral blood cells of coal workers. 61
30442342 2018
47
Spatial analysis of asbestos exposure and occupational health care in Poland during the period 2004-2013. 61
30451463 2018
48
Monsanto, PCBs, and the creation of a "world-wide ecological problem". 61
30401808 2018
49
Breath analysis as a diagnostic and screening tool for malignant pleural mesothelioma: a systematic review. 61
30450290 2018
50
WHO/ILO work-related burden of disease and injury: Protocol for systematic reviews of occupational exposure to dusts and/or fibres and of the effect of occupational exposure to dusts and/or fibres on pneumoconiosis. 61
29958118 2018

Variations for Asbestos Intoxication

Expression for Asbestos Intoxication

Search GEO for disease gene expression data for Asbestos Intoxication.

Pathways for Asbestos Intoxication

GO Terms for Asbestos Intoxication

Sources for Asbestos Intoxication

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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