MCID: ASP004
MIFTS: 45

Asphyxia Neonatorum

Categories: Fetal diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Asphyxia Neonatorum

MalaCards integrated aliases for Asphyxia Neonatorum:

Name: Asphyxia Neonatorum 12 74 52 43 15 37 17 71
Birth Asphyxia 12 32
Asphyxia, in Liveborn Infant 12
Hypoxia, in Liveborn Infant 71
Postnatal Asphyxia 12
Hypoxia Neonatorum 52
Asphyxia - Birth 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11088
ICD9CM 34 768.9
MeSH 43 D001238
SNOMED-CT 67 28314004
ICD10 32 P21 P21.9 P84
UMLS 71 C0004045 C0520599

Summaries for Asphyxia Neonatorum

MalaCards based summary : Asphyxia Neonatorum, also known as birth asphyxia, is related to cardiac arrest and hypoglycemia. An important gene associated with Asphyxia Neonatorum is OXT (Oxytocin/Neurophysin I Prepropeptide), and among its related pathways/superpathways are HIF-1 signaling pathway and Type II diabetes mellitus. The drugs Tocopherol and Oxytocin have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and kidney, and related phenotypes are adipose tissue and homeostasis/metabolism

Wikipedia : 74 Perinatal asphyxia (also known as neonatal asphyxia or birth asphyxia) is the medical condition... more...

Related Diseases for Asphyxia Neonatorum

Diseases related to Asphyxia Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 cardiac arrest 29.8 TTN S100B OXT EPO ENO2
2 hypoglycemia 29.5 SLC16A1 KCNJ11 INS HADH ABCC8
3 hyperinsulinism 29.5 SLC16A1 KCNJ11 INS HADH ABCC8
4 brain injury 29.5 S100B EPO ENO2 CASP3
5 gestational diabetes 29.2 KCNJ11 INS CRP ABCC8
6 intracranial cysts 10.5 S100B ENO2
7 bednar tumor 10.5 S100B ENO2
8 munchausen by proxy 10.5 KCNJ11 ABCC8
9 head injury 10.5 S100B ENO2
10 meningeal melanocytoma 10.5 S100B ENO2
11 papillary ependymoma 10.5 S100B ENO2
12 placenta praevia 10.4 TMEM106C OXT APEH
13 pineocytoma 10.4 S100B ENO2
14 folic acid deficiency anemia 10.4 EPO CRP
15 breast abscess 10.4 OXT CRP
16 maturity-onset diabetes of the young, type 11 10.4 KCNJ11 ABCC8
17 late congenital syphilis 10.4 OXT CRP
18 post-cardiac arrest syndrome 10.4 S100B ENO2
19 chronic duodenal ileus 10.4 KCNJ11 CRP
20 maturity-onset diabetes of the young, type 13 10.4 KCNJ11 ABCC8
21 akinetic mutism 10.4 S100B ENO2
22 subleukemic leukemia 10.4 S100B OXT ENO2
23 aspiration pneumonitis 10.4 OXT CRP
24 maturity-onset diabetes of the young, type 8, with exocrine dysfunction 10.3 KCNJ11 ABCC8
25 balantidiasis 10.3 MPG EPO
26 pre-eclampsia 10.3
27 anoxia 10.3
28 hypoxia 10.3
29 bacterial conjunctivitis 10.3 TMEM106C CRP
30 uterine inversion 10.3 ZBP1 OXT
31 rosai-dorfman disease 10.3 S100B CRP
32 angiomyoma 10.3 HECTD4 ENO2
33 tuberculous epididymitis 10.3 PLEKHG5 CRP
34 preterm premature rupture of the membranes 10.3 OXT CRP APEH
35 ossifying fibromyxoid tumor 10.3 S100B ENO2
36 gallbladder small cell carcinoma 10.3 ENO2 CRP
37 lumbosacral lipoma 10.3 PLEKHG5 HECTD4
38 hemangioblastoma 10.3 S100B EPO ENO2
39 pulmonary edema 10.3 OXT EPO CRP
40 pain agnosia 10.2
41 pneumothorax 10.2
42 encephalopathy 10.2
43 calcific tendinitis 10.2 HECTD4 CRP
44 miliary tuberculosis 10.2 EPO ENO2 CRP
45 intracranial embolism 10.2 ENO2 CRP
46 hypotonia 10.2
47 extraosseous ewing sarcoma 10.2 S100B ENO2
48 hemiplegia 10.1 S100B HECTD4 ENO2
49 alveolar soft part sarcoma 10.1 SLC16A1 ENO2 CRP
50 lymphangitis 10.1 HECTD4 CRP

Graphical network of the top 20 diseases related to Asphyxia Neonatorum:



Diseases related to Asphyxia Neonatorum

Symptoms & Phenotypes for Asphyxia Neonatorum

MGI Mouse Phenotypes related to Asphyxia Neonatorum:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.5 HADH INS KCNJ11 MPG OXT SLC16A1
2 homeostasis/metabolism MP:0005376 9.47 ABCC8 CASP3 CRP EPO HADH INS

Drugs & Therapeutics for Asphyxia Neonatorum

Drugs for Asphyxia Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 99)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tocopherol Approved, Investigational Phase 4 1406-66-2, 54-28-4 14986
2
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
3
Sertraline Approved Phase 4 79617-96-2 68617
4
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
5
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
6 Tocotrienol Investigational Phase 4 6829-55-6
7 Tocopherols Phase 4
8 Tocotrienols Phase 4
9 Chlorhexidine gluconate Phase 4
10 Vaccines Phase 4
11 Dermatologic Agents Phase 4
12 Disinfectants Phase 4
13 Anti-Infective Agents, Local Phase 4
14 Anti-Infective Agents Phase 4
15 Neurotransmitter Agents Phase 4
16 Serotonin Uptake Inhibitors Phase 4
17 Psychotropic Drugs Phase 4
18 Serotonin Agents Phase 4
19 Antidepressive Agents Phase 4
20 Oxytocics Phase 4
21
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
22
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
23
Misoprostol Approved Phase 3 59122-46-2 5282381
24
Dinoprostone Approved Phase 3 363-24-6 5280360
25
Papaverine Approved, Investigational Phase 2, Phase 3 58-74-2, 61-25-6 4680
26
Alprostadil Approved, Investigational Phase 3 745-65-3 149351 5280723
27
Azithromycin Approved Phase 3 83905-01-5 55185 447043
28
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
29 Vasodilator Agents Phase 2, Phase 3
30 Phosphodiesterase Inhibitors Phase 2, Phase 3
31 Pharmaceutical Solutions Phase 3
32 Analgesics Phase 2, Phase 3
33 Anti-Arrhythmia Agents Phase 3
34 Hormones Phase 3
35 Tocolytic Agents Phase 3
36 Calcium, Dietary Phase 3
37 calcium channel blockers Phase 3
38 Anticonvulsants Phase 3
39 Autonomic Agents Phase 2, Phase 3
40 Gastrointestinal Agents Phase 3
41 Anti-Ulcer Agents Phase 3
42 Antacids Phase 3
43 Drotaverin Phase 2, Phase 3
44 Parasympatholytics Phase 2, Phase 3
45 Lactoferrin Phase 3
46 Hematinics Phase 3
47 Epoetin alfa Phase 3 113427-24-0
48
Nitric Oxide Approved Phase 1, Phase 2 10102-43-9 145068
49
Topiramate Approved Phase 2 97240-79-4 5284627
50
Darbepoetin alfa Approved, Investigational Phase 1, Phase 2 209810-58-2, 11096-26-7

Interventional clinical trials:

(show top 50) (show all 97)
# Name Status NCT ID Phase Drugs
1 Single High Dose Vitamin E and Vitamin C in Hypoxic Ischemic Encephalopathy (Following Birth Asphyxia)in Newborns Completed NCT01743742 Phase 4 Vitamin E, Vitamin C
2 Brain Research to Ameliorate Impaired Neurodevelopment (BRAIN): Home-based Intervention A Multicenter Trial of the Global Network for Women's and Children's Health Research Completed NCT00639184 Phase 4
3 A Randomized Controlled Trial to Evaluate the Acceptability, Feasibility and Efficacy of the Use of a Neonatal Package to Reduce Neonatal Infection in a Rural District of Pakistan Completed NCT02279381 Phase 4 Chlorhexidine
4 Z 31801 - A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women Recruiting NCT04094870 Phase 4 Sertraline
5 Continued Versus Discontinued Oxytocin Stimulation of Labour in a Double-blind Randomised Controlled Trial Recruiting NCT02553226 Phase 4 Oxytocin;Placebo
6 Phase III Study of Efficacy of High Dose Erythropoietin to Prevent Hypoxic-ischemic Encephalopathy Sequelae in Term Newborn Unknown status NCT01732146 Phase 3 erythropoietin Beta;Placebo
7 Neonatal Resuscitation in Zambia Completed NCT00097097 Phase 3
8 Achievement of a Targeted Saturation in Extremely Low Gestational Age Neonates Resuscitated With Low or High Oxygen Concentration: A Prospective Randomized Trial Completed NCT00494702 Phase 3
9 Erythropoietin in Perinatal Asphyxia: A Randomized Placebo Controlled Trial Completed NCT02002039 Phase 2, Phase 3 Erythropoietin
10 Magnesium Sulphate in Perinatal Asphyxia: A Randomized Placebo Controlled Trial. Completed NCT00553072 Phase 3 Magnesium sulphate;Normal saline
11 Use of Antispasmodic Drotaverine to Shorten the Length of Labor in Nulliparous Women Completed NCT01639027 Phase 2, Phase 3 Drotaverine;Placebo
12 Evaluation of Systemic Hypothermia Initiated After 6 Hours of Age in Infants ≥36 Weeks Gestation With Hypoxic-Ischemic Encephalopathy: A Bayesian Evaluation. A Protocol for the NICHD Neonatal Research Network Completed NCT00614744 Phase 2, Phase 3
13 A Randomized Controlled Trial of Oral Misoprostol, Low Dose Vaginal Misoprostol and Vaginal Dinoprostone for Induction of Labour Completed NCT03489928 Phase 3 Oral Misoprostol;Vaginal Misoprostol;Dinoprostone
14 Lactoferrin for Prevention of Sepsis in Infants Completed NCT01525316 Phase 3
15 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis and Death: a Phase III Double-blind Randomized Clinical Trial Recruiting NCT03199547 Phase 3 Azithromycin;Placebo Oral Tablet
16 High-dose Erythropoietin for Asphyxia and Encephalopathy Active, not recruiting NCT02811263 Phase 3 Normal saline placebo;Erythropoietin
17 Birth Asphyxia in Uganda: Prevalence, Associated Factors and Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes Not yet recruiting NCT04043299 Phase 3 100% Oxygen
18 Effects of Probiotic Mixture Supplementation and Evaluation of Intestinal Mucosal Tolerance and Gut Microbiome in Newborns With Perinatal Asphyxia Receiving Hypothermic Treatment: a Randomized, Multicentric, Blinded, Controlled Trial Not yet recruiting NCT04145713 Phase 3
19 Optimizing Cooling Strategies at < 6 Hours of Age for Neonatal Hypoxic-Ischemic Encephalopathy Terminated NCT01192776 Phase 3
20 Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes Study Unknown status NCT01913340 Phase 1, Phase 2 Erythropoietin;Normal saline
21 Human Recombinant Erythropoietin (HrEPO) in Asphyxia Neonatorum: A Pilot Trial Completed NCT00945789 Phase 1, Phase 2 Human recombinant erythropoietin
22 Melatonin for Neuroprotection Following Perinatal Asphyxia Completed NCT02071160 Phase 1, Phase 2 Melatonin
23 Safety and Efficacy of Oral Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia: a Pilot Study of the Neonatal Neuroprotection of Asphyxiated Tuscan Infants (NeoNATI) Network Completed NCT01241019 Phase 2 Topiramate in newborns with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
24 Darbe Administration in Newborns Undergoing Cooling for Encephalopathy Completed NCT01471015 Phase 1, Phase 2 Darbepoetin alfa;Darbepoetin alfa;Placebo
25 Effect of Systemic Hypothermia on Neonatal Hypoxic-Ischemic Encephalopathy Completed NCT00817401 Phase 1, Phase 2
26 Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest Completed NCT00797680 Phase 2
27 A Multi-centre, Randomised, Double-blind, Placebo-controlled Phase II Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of 2-Iminobiotin (2-IB) in Neonates With ≥36 Weeks GA With Moderate to Severe Perinatal Asphyxia Terminated NCT01626924 Phase 2 2-Iminobiotin
28 Neonatal Erythropoietin in Asphyxiated Term Newborns: a Phase I Trial Completed NCT00719407 Phase 1 erythropoietin
29 Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia: An Open-label Dose-finding Clinical Trial (Phase Ib Study) Recruiting NCT04169191 Phase 1 Sildenafil Citrate
30 Sildenafil Administration to Treat Neonatal Encephalopathy (SANE) and Repair Brain Injury Secondary to Birth Asphyxia: A Randomized, Double-blind, Placebo-controlled Pilot Phase Ib Study Active, not recruiting NCT02812433 Phase 1 Sildenafil;Ora-Blend
31 Safer Births - New Knowledge and Innovations to Decrease Perinatal Mortality and Morbidity Worldwide Unknown status NCT01869582
32 Validation of Biomarkers of Adverse Neurologic Outcome in Newborns Who Required Resuscitation or Are Suspected to be at Risk for Perinatal Brain Injury and Long-term Adverse Neurological Outcome A Prospective Multicenter Observational Study for Development of a Diagnostic Test Unknown status NCT03357250
33 Prospective Multicenter Study to Evaluate the Validity of the Specified Apgar-score in Asphyxiated Infants Under Resuscitation Unknown status NCT01193751
34 FIRST BREATH: Neonatal Resuscitation in Developing Countries Completed NCT00136708
35 Naushero Feroze Neonatal Survival Project: A Cluster Randomized Trial to Determine the Effectiveness of Package of Community Based Interventions to Reduce Neonatal Deaths Due to Birth Asphyxia, Low Birth Weight & Neonatal Sepsis Completed NCT01350765
36 Asphyxia at Birth : Evolution of Birth Asphyxia Rate, Etiologies and Neonatal Outcome From 2000 to 2016 Completed NCT03227536
37 Intraosseous Infusion for Neonatal Asphyxiated Resuscitation Completed NCT01866358
38 Infant Special Program for In Hospital Resuscitation Education in the Delivery Room - INSPIRE-D Completed NCT02347241
39 Randomized Clinical Trial Assessing Laryngeal Mask Airway (LMA) Versus Face-mask Ventilation (FMV) in Neonatal Resuscitation at Mulago Hospital, Uganda Completed NCT02042118
40 Brain-Cooling for the Treatment of Perinatal Hypoxic-Ischemic Encephalopathy Completed NCT00383305
41 Does Placenta Pathology Predict Outcome of Neonates With Hypoxic Ischemic Encephalopathy?" Completed NCT03284528
42 Verification of Biomarkers to Examine Neonatal Asphyxia Induced Hypoxic-ischemic Encephalopathy. A Prospective Multicenter Observational Study for Development of a Diagnostic Test Completed NCT03354208
43 Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings. Completed NCT02862925
44 Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy Completed NCT00385229 induction of labor
45 Whole Body Hypothermia for the Treatment of Perinatal Asphyxial Encephalopathy Completed NCT00147030
46 Video Laryngoscopy for Enhancing and Maintaining Intubation Skills Completed NCT02572427
47 Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury Completed NCT02445417
48 Effect of Home Based Child Care on Child Mortality and Malnutrition in a Tribal Population of Melghat, India: Cluster Randomised Control Field Trial Completed NCT02473796
49 Evaluation of Two Strategies for Constructive Immediate Feedback in the Development of Skills for Neonatal Resuscitation: a Randomized Clinical Trial Completed NCT03606278
50 Skills and Drills Intervention for Improving Emergency Obstetric and Neonatal Care in Select First Referral Units in Northern Karnataka Completed NCT01865656

Search NIH Clinical Center for Asphyxia Neonatorum

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Asphyxia Neonatorum cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Asphyxia Neonatorum:
Cord blood-derived hematopoietic stem cells for treatment of oxygen deprivation in newborns
Embryonic/Adult Cultured Cells Related to Asphyxia Neonatorum:
Umbilical cord blood-derived hematopoietic stem cells (family)

Cochrane evidence based reviews: asphyxia neonatorum

Genetic Tests for Asphyxia Neonatorum

Anatomical Context for Asphyxia Neonatorum

MalaCards organs/tissues related to Asphyxia Neonatorum:

40
Brain, Heart, Kidney, Placenta, Testes, Bone, Liver

Publications for Asphyxia Neonatorum

Articles related to Asphyxia Neonatorum:

(show top 50) (show all 1953)
# Title Authors PMID Year
1
A Phase IIa Clinical Trial of 2-Iminobiotin for the Treatment of Birth Asphyxia in DR Congo, a Low-Income Country. 61
31960360 2020
2
Restrictive versus routine episiotomy among Southeast Asian term pregnancies: a multicentre randomised controlled trial. 61
31749273 2020
3
Determinants of Birth Asphyxia Among Newborns in Referral Hospitals of Amhara National Regional State, Ethiopia. 61
32021550 2020
4
Risk Factors of Birth Asphyxia Among Neonates Born in Public Hospitals of Tigray, Northern Ethiopia. 61
32021551 2020
5
Description of perinatal adversities in children with attention-deficit/hyperactivity disorder. 61
31854320 2020
6
Perinatal features of Prader-Willi syndrome: a Chinese cohort of 134 patients. 61
31964399 2020
7
Clinical features and aetiology of cerebral palsy in children from Cross River State, Nigeria. 61
31959596 2020
8
Cesarean section does not affect neonatal outcomes of pregnancies complicated with preterm premature rupture of membranes. 61
31923101 2020
9
Neonatal complications in women with premature rupture of membranes (PROM) at term and near term and its correlation with time lapsed since PROM to delivery. 61
31726941 2020
10
Efficacy of Progressive Muscle Relaxation on Pregnancy Outcome among Anxious Indian Primi Mothers. 61
31956594 2020
11
Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial. 61
31923193 2020
12
Fetal heart rate monitoring practices at a public hospital in Northern Uganda - what health workers document, do and say. 61
31955672 2020
13
Oxygen metabolism and oxygenation of the newborn. 61
32037265 2020
14
Diagnosis and Management of Critical Congenital Heart Diseases in the Newborn. 61
31989462 2020
15
Cause-specific neonatal morbidity and mortality in the Solomon Islands: An assessment of data from four hospitals over a three-year period. 61
31820849 2019
16
A decision tree model of cerebral palsy based on risk factors. 61
31842640 2019
17
Cesarean section does not affect neonatal outcomes of pregnancies complicated with preterm premature rupture of membranes. 61
31855961 2019
18
Maternal risk factors for birth asphyxia in low-resource communities. A systematic review of the literature. 61
31825270 2019
19
Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study. 61
31892353 2019
20
Prevalence and contributing factors of birth asphyxia among the neonates delivered at Nigist Eleni Mohammed memorial teaching hospital, Southern Ethiopia: a cross-sectional study. 61
31888542 2019
21
Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report. 61
32026066 2019
22
How fast did newborns die in Nigeria from 2009-2013: a time-to-death analysis using Verbal /Social Autopsy data. 61
31360450 2019
23
Neonatal mortality and its determinates in public hospitals of Gamo and Gofa zones, southern Ethiopia: prospective follow up study. 61
31842806 2019
24
Predictions of Hypoxic-Ischemic Encephalopathy by Umbilical Cord Blood Lactate in Newborns with Birth Asphyxia. 61
32010377 2019
25
Gamma Knife Radiosurgical Pallidotomy for Dystonia: Not a Fallen Angel. 61
31857549 2019
26
Congenital Heart Disease and Autism: A Case-Control Study. 61
31601611 2019
27
Neonatal Morbidity in Late Preterm Infants Associated with Intrauterine Growth Restriction. 61
32010382 2019
28
A Retrospective Cohort Study of Safety Outcomes in New Zealand Infants Exposed to Tdap Vaccine in Utero. 61
31614582 2019
29
Trend of Cesarean Section Rates and Correlations with Adverse Maternal and Neonatal Outcomes: A Secondary Analysis of Thai Universal Coverage Scheme Data. 61
31673478 2019
30
Effect of Acetyl-L-carnitine Used for Protection of Neonatal Hypoxic-Ischemic Brain Injury on Acute Kidney Changes in Male and Female Rats. 61
31041669 2019
31
Placental clearance/synthesis of neurobiomarkers GFAP and UCH-L1 in healthy term neonates and those with moderate-severe neonatal encephalopathy. 61
31132788 2019
32
[Short-term prognosis of the co-twin who survives after single intrauterine fetal demise]. 61
31506147 2019
33
Prospective qualification of early cerebral biomarkers in a randomised trial of treatment with xenon combined with moderate hypothermia after birth asphyxia. 61
31451436 2019
34
Birth asphyxia following delayed recognition and response to abnormal labour progress and fetal distress in a 31-year-old multiparous Malawian woman. 61
31511259 2019
35
Evaluation of novel biomarkers for early diagnosis of acute kidney injury in asphyxiated full-term newborns: a case-control study. 61
31536999 2019
36
Making neonatal intensive care: cost effective. 61
31446821 2019
37
Distinct outcomes of labetalol exposed infants: case reports and systematic review. 61
31510808 2019
38
Screening circulating proteins to identify biomarkers of fetal macrosomia. 61
31533811 2019
39
Peripartum interventions resulting in reduced perinatal mortality rates, and birth asphyxia rates, over 18 years in a tertiary centre in South India: a retrospective study. 61
31257695 2019
40
Readiness to treat and factors associated with survival of newborns with breathing difficulties in Ethiopia. 61
31391044 2019
41
Clinico-etiological Profile and Developmental Status of Infants Aged 1-24 months with Epilepsy. 61
30976964 2019
42
Incidence of epilepsy in children born prematurely and small for gestational age at term gestation: A population-based cohort study. 61
31464013 2019
43
Theophylline and aminophylline for prevention of acute kidney injury in neonates and children: a systematic review. 61
30798259 2019
44
Improving the quality of neonatal data capture and clinical care at a tertiary-care hospital in Uganda through enhanced surveillance, training and mentorship. 61
31290375 2019
45
Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy. 61
31308390 2019
46
Morbidity Patterns of Late Preterm Babies Born Small for Gestation. 61
30863925 2019
47
Distinct mortality patterns at 0-2 days versus the remaining neonatal period: results from population-based assessment in the Indian state of Bihar. 61
31319860 2019
48
Evaluating WHO-Recommended Interventions for Preterm Birth: A Mathematical Model of the Potential Reduction of Preterm Mortality in Sub-Saharan Africa. 61
31249020 2019
49
Child mortality trends and causes of death in South Africa, 1997 - 2012, and the importance of a national burden of disease study. 61
31266573 2019
50
Object Detection During Newborn Resuscitation Activities. 61
31247581 2019

Variations for Asphyxia Neonatorum

Expression for Asphyxia Neonatorum

Search GEO for disease gene expression data for Asphyxia Neonatorum.

Pathways for Asphyxia Neonatorum

Pathways related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.37 INS EPO ENO2
2
Show member pathways
11.11 KCNJ11 INS ABCC8
3 10.57 KCNJ11 INS HADH ABCC8

GO Terms for Asphyxia Neonatorum

Cellular components related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inward rectifying potassium channel GO:0008282 8.62 KCNJ11 ABCC8

Biological processes related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.76 KCNJ11 HADH CASP3 ABCC8
2 response to estradiol GO:0032355 9.61 OXT KCNJ11 CASP3
3 memory GO:0007613 9.58 S100B OXT ABCC8
4 regulation of insulin secretion GO:0050796 9.5 SLC16A1 KCNJ11 ABCC8
5 response to glucocorticoid GO:0051384 9.43 S100B OXT CASP3
6 negative regulation of blood vessel diameter GO:0097756 9.37 INS CRP
7 glucose metabolic process GO:0006006 9.33 KCNJ11 INS HECTD4
8 acute-phase response GO:0006953 9.13 INS EPO CRP
9 negative regulation of insulin secretion GO:0046676 8.8 KCNJ11 HADH ABCC8

Molecular functions related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 OXT INS EPO
2 protease binding GO:0002020 8.8 TTN INS CASP3

Sources for Asphyxia Neonatorum

3 CDC
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11 DGIdb
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32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
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44 MESH via Orphanet
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57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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