MCID: ASP004
MIFTS: 50

Asphyxia Neonatorum

Categories: Fetal diseases, Neuronal diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Asphyxia Neonatorum

MalaCards integrated aliases for Asphyxia Neonatorum:

Name: Asphyxia Neonatorum 12 74 20 44 15 37 17 71
Birth Asphyxia 12 32
Asphyxia, in Liveborn Infant 12
Hypoxia, in Liveborn Infant 71
Postnatal Asphyxia 12
Hypoxia Neonatorum 20
Asphyxia - Birth 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11088
ICD9CM 34 768.9
MeSH 44 D001238
SNOMED-CT 67 413654009
ICD10 32 P21 P21.9 P84
UMLS 71 C0004045 C0520599

Summaries for Asphyxia Neonatorum

Disease Ontology : 12 A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain.

MalaCards based summary : Asphyxia Neonatorum, also known as birth asphyxia, is related to neonatal hypoxic and ischemic brain injury and cerebral hypoxia. An important gene associated with Asphyxia Neonatorum is OXT (Oxytocin/Neurophysin I Prepropeptide), and among its related pathways/superpathways are Folate Metabolism and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Tocopherol and Sertraline have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and placenta, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 74 Perinatal asphyxia (also known as neonatal asphyxia or birth asphyxia) is the medical condition... more...

Related Diseases for Asphyxia Neonatorum

Diseases related to Asphyxia Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 552)
# Related Disease Score Top Affiliating Genes
1 neonatal hypoxic and ischemic brain injury 30.8 ENO2 BDNF
2 cerebral hypoxia 30.3 NOS1 CASP3
3 newborn respiratory distress syndrome 30.0 CRP ALB ABCC8
4 hypoglycemia 30.0 SLC16A1 KCNJ11 INS HADH ABCC8
5 hyperinsulinism 30.0 SLC16A1 KCNJ11 INS HADH ABCC8
6 bilirubin metabolic disorder 30.0 OXT CRP ALB
7 cardiac arrest 29.9 S100B EPO ENO2 ALB
8 gestational diabetes 29.8 KCNJ11 INS IL6 CRP ABCC8
9 pre-eclampsia 29.6 OXT INS IL6 IL1B CRP ALB
10 chorioamnionitis 29.6 OXT IL6 IL1B CRP
11 carotid artery occlusion 29.6 IL1B CASP3 BDNF
12 perinatal necrotizing enterocolitis 29.6 IL6 IL1B CRP ALB
13 pain agnosia 29.5 OXT IL6 IL1B BDNF ALB
14 ischemia 29.5 NOS1 EPO CASP3 BDNF
15 blood coagulation disease 29.4 IL6 IL1B EPO CRP ALB
16 brain edema 29.3 IL6 IL1B CRP ALB
17 attention deficit-hyperactivity disorder 29.3 S100B OXT NOS1 IL6 BDNF
18 persistent fetal circulation syndrome 29.2 OXT INS IL6 IL1B ALB
19 cerebral palsy 29.2 S100B NOS1 IL6 IL1B BDNF
20 congestive heart failure 29.0 INS IL6 IL1B EPO CRP ALB
21 chronic kidney disease 28.9 INS IL6 IL1B EPO CRP ALB
22 thrombocytopenia 28.9 IL6 IL1B EPO CRP CASP3 ALB
23 brain injury 28.8 S100B IL6 IL1B EPO ENO2 CASP3
24 intracranial cysts 10.4 S100B ENO2
25 bednar tumor 10.4 S100B ENO2
26 vibrio vulnificus infection 10.4 IL6 EPO
27 meningeal melanocytoma 10.4 S100B ENO2
28 munchausen by proxy 10.4 KCNJ11 ABCC8
29 head injury 10.4 S100B ENO2
30 folic acid deficiency anemia 10.4 EPO CRP
31 gallbladder small cell carcinoma 10.4 ENO2 CRP
32 cold agglutinin disease 10.4 IL6 CRP
33 breast abscess 10.4 OXT CRP
34 subleukemic leukemia 10.4 S100B OXT ENO2
35 malignant otitis externa 10.4 INS CRP
36 uvulitis 10.4 INS CRP
37 retroperitoneal hemangiopericytoma 10.3 INS ENO2
38 systemic autoimmune disease 10.3 IL6 CRP
39 cryopyrin-associated periodic syndrome 10.3 IL6 CRP
40 pineocytoma 10.3 S100B ENO2
41 post-cardiac arrest syndrome 10.3 S100B IL6 ENO2
42 cavernous sinus thrombosis 10.3 INS CRP
43 iritis 10.3 IL6 EPO CRP
44 alexithymia 10.3 OXT IL6 CRP
45 coronary artery vasospasm 10.3 KCNJ11 CRP ABCC8
46 silent myocardial infarction 10.3 INS CRP
47 neurogenic arthropathy 10.3 INS CRP
48 cerebral arterial disease 10.3 S100B IL6 CRP
49 factitious disorder 10.3 KCNJ11 INS ABCC8
50 seizure disorder 10.3

Graphical network of the top 20 diseases related to Asphyxia Neonatorum:



Diseases related to Asphyxia Neonatorum

Symptoms & Phenotypes for Asphyxia Neonatorum

MGI Mouse Phenotypes related to Asphyxia Neonatorum:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.26 BDNF CASP3 ENO2 GATM IL6 INS
2 homeostasis/metabolism MP:0005376 10.25 ABCC8 ALB BDNF CASP3 CRP EPO
3 growth/size/body region MP:0005378 10.21 ABCC8 BDNF CASP3 ENO2 GATM HADH
4 cellular MP:0005384 10.2 ALB BDNF CASP3 ENO2 EPO GATM
5 adipose tissue MP:0005375 10.15 GATM HADH IL6 INS KCNJ11 NOS1
6 endocrine/exocrine gland MP:0005379 10.14 ABCC8 ALB BDNF CASP3 GATM HADH
7 digestive/alimentary MP:0005381 10.09 ALB BDNF CASP3 GATM IL6 INS
8 integument MP:0010771 9.96 BDNF CASP3 EPO GATM IL1B IL6
9 muscle MP:0005369 9.81 ALB CASP3 EPO GATM IL6 INS
10 no phenotypic analysis MP:0003012 9.5 ABCC8 BDNF CASP3 INS KCNJ11 NOS1
11 renal/urinary system MP:0005367 9.28 ALB CASP3 GATM HADH IL6 INS

Drugs & Therapeutics for Asphyxia Neonatorum

Drugs for Asphyxia Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 74)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tocopherol Approved, Investigational Phase 4 1406-66-2
2
Sertraline Approved Phase 4 79617-96-2 68617
3
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
4
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
5 Tocotrienol Investigational Phase 4 6829-55-6
6 Trace Elements Phase 4
7 Protective Agents Phase 4
8 Micronutrients Phase 4
9 Antioxidants Phase 4
10 Vitamins Phase 4
11 Tocotrienols Phase 4
12 Tocopherols Phase 4
13 Nutrients Phase 4
14 Neurotransmitter Agents Phase 4
15 Psychotropic Drugs Phase 4
16 Anti-Retroviral Agents Phase 4
17 Serotonin Uptake Inhibitors Phase 4
18
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
19
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
20 Vasodilator Agents Phase 2, Phase 3
21 Anesthetics Phase 3
22 Analgesics Phase 3
23 Anti-Arrhythmia Agents Phase 3
24 Hormones Phase 3
25 Tocolytic Agents Phase 3
26 Calcium, Dietary Phase 3
27 Anticonvulsants Phase 3
28 calcium channel blockers Phase 3
29 Parasympatholytics Phase 2, Phase 3
30 Drotaverin Phase 2, Phase 3
31 Hematinics Phase 3
32 Epoetin alfa Phase 3 113427-24-0
33
Calcium Nutraceutical Phase 3 7440-70-2 271
34
Nitric Oxide Approved Phase 1, Phase 2 10102-43-9 145068
35
Melatonin Approved, Nutraceutical, Vet_approved Phase 1, Phase 2 73-31-4 896
36 Respiratory System Agents Phase 1, Phase 2
37 Anti-Asthmatic Agents Phase 1, Phase 2
38 Bronchodilator Agents Phase 1, Phase 2
39 Endothelium-Dependent Relaxing Factors Phase 1, Phase 2
40 Pharmaceutical Solutions Phase 2
41
Sodium citrate Approved, Investigational Phase 1 68-04-2
42
Citric acid Approved, Nutraceutical, Vet_approved Phase 1 77-92-9 311
43 Phosphodiesterase Inhibitors Phase 1
44 Citrate Phase 1
45 Phosphodiesterase 5 Inhibitors Phase 1
46 Sildenafil Citrate Phase 1 171599-83-0
47
Nicotine Approved 54-11-5 942 89594
48
Metronidazole Approved 443-48-1 4173
49
chloroquine Approved, Investigational, Vet_approved 54-05-7 2719
50
Misoprostol Approved 59122-46-2 5282381

Interventional clinical trials:

(show top 50) (show all 69)
# Name Status NCT ID Phase Drugs
1 The First-day High Dose Vitamin E and Vitamin C in Hypoxic Ischemic Encephalopathy (Following Birth Asphyxia) in Newborns Completed NCT01743742 Phase 4 Vitamin E, Vitamin C
2 Z 31801 - A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women Completed NCT04094870 Phase 4 Sertraline
3 Achievement of a Targeted Saturation in Extremely Low Gestational Age Neonates Resuscitated With Low or High Oxygen Concentration: A Prospective Randomized Trial Completed NCT00494702 Phase 3
4 Neonatal Resuscitation in Zambia Completed NCT00097097 Phase 3
5 Magnesium Sulphate in Perinatal Asphyxia: A Randomized Placebo Controlled Trial. Completed NCT00553072 Phase 3 Magnesium sulphate;Normal saline
6 Erythropoietin in Perinatal Asphyxia: A Randomized Placebo Controlled Trial Completed NCT02002039 Phase 2, Phase 3 Erythropoietin
7 Use of Antispasmodic Drotaverine to Shorten the Length of Labor in Nulliparous Women Completed NCT01639027 Phase 2, Phase 3 Drotaverine;Placebo
8 Birth Asphyxia in Uganda: Prevalence, Associated Factors and Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes Recruiting NCT04043299 Phase 3 100% Oxygen;21% oxygen
9 High-dose Erythropoietin for Asphyxia and Encephalopathy Active, not recruiting NCT02811263 Phase 3 Normal saline placebo;Erythropoietin
10 Effects of Probiotic Mixture Supplementation and Evaluation of Intestinal Mucosal Tolerance and Gut Microbiome in Newborns With Perinatal Asphyxia Receiving Hypothermic Treatment: a Randomized, Multicentric, Blinded, Controlled Trial Not yet recruiting NCT04145713 Phase 3
11 Human Recombinant Erythropoietin (HrEPO) in Asphyxia Neonatorum: A Pilot Trial Completed NCT00945789 Phase 1, Phase 2 Human recombinant erythropoietin
12 Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes Study Completed NCT01913340 Phase 1, Phase 2 Erythropoietin;Normal saline
13 Melatonin for Neuroprotection Following Perinatal Asphyxia Completed NCT02071160 Phase 1, Phase 2 Melatonin
14 A Multi-centre, Randomised, Double-blind, Placebo-controlled Phase II Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of 2-Iminobiotin (2-IB) in Neonates With ≥36 Weeks GA With Moderate to Severe Perinatal Asphyxia Terminated NCT01626924 Phase 2 2-Iminobiotin
15 Neonatal Erythropoietin in Asphyxiated Term Newborns: a Phase I Trial Completed NCT00719407 Phase 1 erythropoietin
16 Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia: An Open-label Dose-finding Clinical Trial (Phase Ib Study) Recruiting NCT04169191 Phase 1 Sildenafil Citrate
17 Sildenafil Administration to Treat Neonatal Encephalopathy (SANE) and Repair Brain Injury Secondary to Birth Asphyxia: A Randomized, Double-blind, Placebo-controlled Pilot Phase Ib Study Active, not recruiting NCT02812433 Phase 1 Sildenafil;Ora-Blend
18 Development of a Mobile Application Through User Centered Design to Improve Helping Babies Breath Skills Retention Unknown status NCT03577054
19 Brain-Cooling for the Treatment of Perinatal Hypoxic-Ischemic Encephalopathy Completed NCT00383305
20 Lufwanyama Neonatal Survival Project Completed NCT00518856
21 Infant Special Program for In Hospital Resuscitation Education in the Delivery Room - INSPIRE-D Completed NCT02347241
22 Naushero Feroze Neonatal Survival Project: A Cluster Randomized Trial to Determine the Effectiveness of Package of Community Based Interventions to Reduce Neonatal Deaths Due to Birth Asphyxia, Low Birth Weight & Neonatal Sepsis Completed NCT01350765
23 Asphyxia at Birth : Evolution of Birth Asphyxia Rate, Etiologies and Neonatal Outcome From 2000 to 2016 Completed NCT03227536
24 Randomized Clinical Trial Assessing Laryngeal Mask Airway (LMA) Versus Face-mask Ventilation (FMV) in Neonatal Resuscitation at Mulago Hospital, Uganda Completed NCT02042118
25 FIRST BREATH: Neonatal Resuscitation in Developing Countries Completed NCT00136708
26 Intraosseous Infusion for Neonatal Asphyxiated Resuscitation Completed NCT01866358
27 Video Laryngoscopy for Enhancing and Maintaining Intubation Skills Completed NCT02572427
28 Whole Body Hypothermia for the Treatment of Perinatal Asphyxial Encephalopathy Completed NCT00147030
29 Does Placenta Pathology Predict Outcome of Neonates With Hypoxic Ischemic Encephalopathy?" Completed NCT03284528
30 Evaluation of Two Strategies for Constructive Immediate Feedback in the Development of Skills for Neonatal Resuscitation: a Randomized Clinical Trial Completed NCT03606278
31 Validation of Biomarkers of Adverse Neurologic Outcome in Newborns Who Required Resuscitation or Are Suspected to be at Risk for Perinatal Brain Injury and Long-term Adverse Neurological Outcome A Prospective Multicenter Observational Study for Development of a Diagnostic Test Completed NCT03357250
32 Verification of Biomarkers to Examine Neonatal Asphyxia Induced Hypoxic-ischemic Encephalopathy. A Prospective Multicenter Observational Study for Development of a Diagnostic Test Completed NCT03354208
33 Virtual Psychiatric Care for Perinatal Depression (Virtual-PND): A Pilot Randomized Controlled Trial Completed NCT03291600
34 Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings. Completed NCT02862925
35 Skills and Drills Intervention for Improving Emergency Obstetric and Neonatal Care in Select First Referral Units in Northern Karnataka Completed NCT01865656
36 Safer Births - New Knowledge and Innovations to Decrease Perinatal Mortality and Morbidity Worldwide Completed NCT01869582
37 Characterization of the Cord Blood Stem Cell in Situation of Neonatal Asphyxia Completed NCT01284673
38 Early or Late Cord Clamping in the Depressed Neonate - a Randomized Controlled Study in a Low-income Facility Setting for Improved Early Neonatal Outcome Completed NCT02727517
39 Effect of Home Based Child Care on Child Mortality and Malnutrition in a Tribal Population of Melghat, India: Cluster Randomised Control Field Trial Completed NCT02473796
40 Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression Completed NCT02979444
41 Saving Lives at Birth in Uganda: Building and Sustaining Capacity of Frontline Health Workers - A Program Evaluation Completed NCT03254628 oxytocin and misoprostol
42 Continuous Training and Certification in Neonatal Resuscitation in Remote Areas Using a Multi-platform Information and Communication Technology Intervention Compared to Standard Training: A Randomized Cluster Trial Completed NCT03210194
43 Autophagy, Mitophagy, Inflammation and Plasmatic Concentration of Melatonin in Newborn With Metabolic Acidosis at Birth Recruiting NCT03897101
44 Echocardiography Substrudy of the Umbilical Cord Milking in Non Vigorous Infants Trial Recruiting NCT03798093
45 Umbilical Cord Milking in Non-Vigorous Infants Recruiting NCT03631940
46 Umbilical Cord Milking in Non-Vigorous Infants - NIRS Sub-study (MINVI_NIRS) Recruiting NCT03621956
47 Standard 6-sec Method Versus Tap-based Application Method to Assess Heart Rate at Birth - a Randomized Controlled Trial Recruiting NCT03913533
48 Validation of Biomarkers of Adverse Neurologic Outcome in Newborns at Risk for Perinatal Brain Injury - Study on Neuro-developmental Follow-up at 2 Years A Prospective Multicenter Observational Study for Development of a Diagnostic Test Recruiting NCT04714775
49 SAVE (Sustained Cord Circulation Awaiting VEntilation) Recruiting NCT04070560
50 Fentanyl and Clonidine for Analgesia During Hypothermia in Term Asphyxiated Infants - a Prospective Pharmacokinetic/Pharmacodynamic/Pharmacogenetic Observational Study. Cohort 1 in The SANNI Project. Recruiting NCT03177980 Fentanyl;Fentanyl and clonidine

Search NIH Clinical Center for Asphyxia Neonatorum

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Asphyxia Neonatorum cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Asphyxia Neonatorum:
Cord blood-derived hematopoietic stem cells for treatment of oxygen deprivation in newborns
Embryonic/Adult Cultured Cells Related to Asphyxia Neonatorum:
Umbilical cord blood-derived hematopoietic stem cells (family)

Cochrane evidence based reviews: asphyxia neonatorum

Genetic Tests for Asphyxia Neonatorum

Anatomical Context for Asphyxia Neonatorum

MalaCards organs/tissues related to Asphyxia Neonatorum:

40
Brain, Heart, Placenta, Kidney, Pituitary, Endothelial, Thalamus

Publications for Asphyxia Neonatorum

Articles related to Asphyxia Neonatorum:

(show top 50) (show all 2057)
# Title Authors PMID Year
1
Burden and consequence of birth defects in Nepal-evidence from prospective cohort study. 61
33588792 2021
2
Molecular Diagnostic Yield of Exome Sequencing in Patients With Cerebral Palsy. 61
33528536 2021
3
Health care workers' experiences of managing foetal distress and birth asphyxia at health facilities in Northern Uganda. 61
33546720 2021
4
Birthweight is an independent predictor of birth asphyxia in twins: A retrospective cross-sectional cohort study of 5337 Chinese twins. 61
33387841 2021
5
Phenobarbital, midazolam, bumetanide, and neonatal seizures: The devil is in the details. 61
33534145 2021
6
Towards multimodal brain monitoring in asphyxiated newborns with amplitude-integrated EEG and simultaneous somatosensory evoked potentials. 61
33310460 2021
7
Perinatal death in Northern Uganda: incidence and risk factors in a community-based prospective cohort study. 61
33446087 2021
8
Quantification of Posterior Risk Related to Intrapartum FIGO 2015 Criteria for Cardiotocography in the Second Stage of Labor. 61
33508830 2021
9
Moderate rate of implementation of spinal anesthesia for cesarean section: does it improve neonatal well-being? A case-control study. 61
33420309 2021
10
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya. 61
33444346 2021
11
Timing and causes of neonatal mortality in Tamale Teaching Hospital, Ghana: A retrospective study. 61
33439915 2021
12
Implementation of a referral and expert advice call Center for Maternal and Newborn Care in the resource constrained health system context of the Greater Accra region of Ghana. 61
33441115 2021
13
How common is substandard obstetric care in adverse events of birth asphyxia, shoulder dystocia and postpartum hemorrhage? Findings from an external inspection of Norwegian maternity units. 61
32668008 2021
14
Perinatal Infection: A Major Contributor to Efficacy of Cooling in Newborns Following Birth Asphyxia. 61
33445791 2021
15
CD15 immunostaining improves placental diagnosis of fetal hypoxia. 61
33545630 2021
16
Association between Hyperbilirubinemia and Hearing Screen Failure in the Neonatal Intensive Care Unit in Infants Born Preterm. 61
33359471 2021
17
Molecular Basis of Sex Difference in Neuroprotection induced by Hypoxia Preconditioning in Zebrafish. 61
32862360 2020
18
Monocytic Infiltrates Contribute to Autistic-like Behaviors in a Two-Hit Model of Neurodevelopmental Defects. 61
33127853 2020
19
Phenobarbital and midazolam suppress neonatal seizures in a noninvasive rat model of birth asphyxia, whereas bumetanide is ineffective. 61
33258158 2020
20
A physiologically validated rat model of term birth asphyxia with seizure generation after, not during, brain hypoxia. 61
33338272 2020
21
50 Years Ago in TheJournalofPediatrics: Magnesium and Birth Asphyxia. 61
33228912 2020
22
Hyperinsulinemic hypoglycemia in children and adolescents: Recent advances in understanding of pathophysiology and management. 61
32185602 2020
23
Assessing the changes in childbirth care practices and neonatal outcomes in Western China: pre-comparison and post-comparison study on early essential newborn care interventions. 61
33371038 2020
24
A Randomized Trial of Laryngeal Mask Airway in Neonatal Resuscitation. 61
33252870 2020
25
Stillbirth 2010-2018: a prospective, population-based, multi-country study from the Global Network. 61
33256783 2020
26
Can an mhealth clinical decision-making support system improve adherence to neonatal healthcare protocols in a low-resource setting? 61
33243172 2020
27
Clinico-Biochemical Correlation in Birth Asphyxia and Its Effects on Outcome. 61
33312805 2020
28
Correlation of Thompson Score in Predicting Early Outcome of Newborn with Birth Asphyxia. 61
33210631 2020
29
Maternal risk factors for birth asphyxia in low-resource communities. A systematic review of the literature. 61
31825270 2020
30
Late Pregnancy Vitamin D Deficiency is Associated with Doubled Odds of Birth Asphyxia and Emergency Caesarean Section: A Prospective Cohort Study. 61
32844359 2020
31
Activity Recognition From Newborn Resuscitation Videos. 61
32149702 2020
32
Neonatal deaths in rural Karnataka, India 2014-2018: a prospective population-based observational study in a low-resource setting. 61
33256777 2020
33
Oral herbal medicine for women with intrahepatic cholestasis in pregnancy: a systematic review of randomized controlled trials. 61
33028282 2020
34
A practice improvement package at scale to improve management of birth asphyxia in Rwanda: a before-after mixed methods evaluation. 61
33023484 2020
35
Prevalence and associated factors of birth asphyxia among live births at Debre Tabor General Hospital, North Central Ethiopia. 61
33115413 2020
36
Liver abscess in early infancy with no underlying risk factors: a case series. 61
33070703 2020
37
Admissions to a Low-Resource Neonatal Unit in Malawi Using a Mobile App: Digital Perinatal Outcome Audit. 61
33084581 2020
38
Helping Babies Breathe Global Development Alliance and the Power of Partnerships. 61
33004637 2020
39
Discharge against medical advice from a Mission tertiary hospital, South-West, Nigeria. 61
33047688 2020
40
N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats. 61
32957477 2020
41
Implementation of the Perinatal Death Surveillance and Response guidelines: Lessons from annual health system strengthening interventions in the Rwenzori Sub-Region, Western Uganda. 61
32802370 2020
42
A Glutathione Precursor Reduces Oxidative Injury to Cultured Embryonic Cardiomyocytes. 61
30277904 2020
43
Neonatal Adrenal Hemorrhage: A Case Series. 61
32898884 2020
44
Magnitude, trend, and causes of under-five mortality from Kilite-Awlaelo health demographic surveillance database, northern Ethiopia, 2009-2017. 61
32993625 2020
45
Clinical profile and outcome of neonatal pneumothorax in resource-limited neonatal intensive care unit. 61
32981419 2020
46
Maternal and Fetal Outcome in Emergency versus Elective Caesarean Section. 61
32969374 2020
47
Trends, patterns and cause-specific neonatal mortality in Tanzania: a hospital-based retrospective survey. 61
32975558 2020
48
Admission of full-term infants to the neonatal intensive care unit: a 9.5-year review in a tertiary teaching hospital. 61
30624998 2020
49
Automatic identification of stimulation activities during newborn resuscitation using ECG and accelerometer signals. 61
32283386 2020
50
Evaluation of the role of ischemia modified albumin in neonatal hypoxic-ischemic encephalopathy. 61
32746533 2020

Variations for Asphyxia Neonatorum

Expression for Asphyxia Neonatorum

Search GEO for disease gene expression data for Asphyxia Neonatorum.

Pathways for Asphyxia Neonatorum

GO Terms for Asphyxia Neonatorum

Cellular components related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.81 S100B OXT INS IL6 IL1B EPO
2 extracellular space GO:0005615 9.32 S100B OXT INS IL6 IL1B EPO
3 inward rectifying potassium channel GO:0008282 8.96 ABCC8 KCNJ11

Biological processes related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.75 BDNF IL6 NOS1
2 memory GO:0007613 9.73 OXT BDNF ABCC8
3 cellular response to organic cyclic compound GO:0071407 9.7 SLC16A1 IL1B CASP3
4 response to glucocorticoid GO:0051384 9.67 CASP3 IL6 OXT
5 learning or memory GO:0007611 9.65 CASP3 GATM S100B
6 response to activity GO:0014823 9.61 HADH IL6 OXT
7 positive regulation of neuroinflammatory response GO:0150078 9.57 IL6 IL1B
8 negative regulation of lipid storage GO:0010888 9.55 CRP IL6
9 response to lipopolysaccharide GO:0032496 9.55 ABCC8 CASP3 EPO IL1B NOS1
10 positive regulation of prostaglandin secretion GO:0032308 9.54 IL1B OXT
11 negative regulation of insulin secretion GO:0046676 9.54 ABCC8 HADH KCNJ11
12 creatine metabolic process GO:0006600 9.51 GATM SLC6A8
13 cellular response to organic substance GO:0071310 9.5 IL1B CASP3 ABCC8
14 vascular endothelial growth factor production GO:0010573 9.46 IL1B IL6
15 negative regulation of neurogenesis GO:0050768 9.43 ABCC8 IL1B IL6
16 negative regulation of calcium ion transport into cytosol GO:0010523 9.4 EPO NOS1
17 acute-phase response GO:0006953 9.26 CRP EPO IL6 INS
18 regulation of insulin secretion GO:0050796 9.1 ABCC8 HADH IL1B IL6 KCNJ11 SLC16A1

Molecular functions related to Asphyxia Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATP-activated inward rectifier potassium channel activity GO:0015272 8.62 ABCC8 KCNJ11

Sources for Asphyxia Neonatorum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....