Aspiration Pneumonia

Categories: Gastrointestinal diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 74 29 6 15 71
Pneumonia, Aspiration 43 17
Aspiration Pneumonitis 71
Pneumonia Aspiration 54


External Ids:

Disease Ontology 12 DOID:0050152
MeSH 43 D011015
SNOMED-CT 67 47839005
ICD10 32 J69.0
UMLS 71 C0032290 C1761609

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to eclampsia and aspiration pneumonitis. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are Folate Metabolism and amb2 Integrin signaling. The drugs Magnesium oxide and Magnesium citrate have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and colon, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 74 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 627)
# Related Disease Score Top Affiliating Genes
1 eclampsia 32.5 F2 ALB ACE
2 aspiration pneumonitis 32.4 TEF SLC22A4 F3 CRP ATP4A ATP12A
3 lung abscess 30.9 LACTB IL6 CRP ALB
4 bronchiolitis 30.8 IL6 IL17A CRP
5 bronchopneumonia 30.8 IL6 CRP ALB
6 cerebrovascular disease 30.5 IL6 F2 CRP ACE
7 periodontitis, chronic 30.5 MMP8 IL6
8 pulmonary edema 30.4 PIK3C2A F2 CRP ACE
9 hernia, hiatus 30.4 TEF CRP ATP4A ATP12A
10 peptic ulcer disease 30.4 ATP4A ATP12A ALB
11 laryngeal disease 30.4 MMP8 ATP4A ATP12A
12 bacterial pneumonia 30.3 LACTB IL6 IL17A CRP ALB
13 constipation 30.3 TAC1 CHAT ATP4A ATP12A
14 periodontitis 30.3 MMP8 IL6 IL17A CRP
15 esophageal disease 30.3 TEF ATP4A ATP12A ALB
16 bronchitis 30.2 TAC1 LACTB IL6 CRP ALB
17 vasculitis 30.2 ITGAM IL6 IL17A CRP
18 peptic esophagitis 30.2 IL6 ATP4A ATP12A ALB
19 cranial nerve palsy 30.2 CRP ALB ACE
20 klebsiella pneumonia 30.2 LACTB IL17A CRP ALB
21 viral pneumonia 30.2 IL6 IL17A CRP
22 duodenal obstruction 30.1 TEF ATP4A ATP12A ALB
23 left bundle branch hemiblock 30.1 PIK3C2A CRP ACE
24 pneumonia 30.1 PIK3C2A MMP8 LACTB ITGAM IL6 IL17A
25 common cold 30.1 IL6 IL17A ALB
26 ileus 30.1 IL6 IL17A F2 CRP
27 gas gangrene 30.1 PIK3C2A IL6 CRP
28 bacterial infectious disease 30.0 ITGAM IL6 IL17A CRP
29 lipid pneumonia 30.0 NPC2 CRP
30 sleep disorder 30.0 IL6 CRP ACE
31 bronchiolitis obliterans 29.9 MMP8 IL6 IL17A CRP
32 gastroenteritis 29.9 LACTB IL6 CRP ALB
33 pulmonary tuberculosis 29.9 IL6 IL17A CRP ALB
34 uremia 29.9 ITGAM IL6 CRP ALB ACE
35 vascular dementia 29.9 IL6 CRP CHAT ACE
36 hepatic encephalopathy 29.9 IL6 F2 ALB
37 leptin deficiency or dysfunction 29.9 IL6 CRP ALB
38 pulmonary embolism 29.8 F3 F2 CRP ALB ACE
39 otitis media 29.8 LACTB IL6 IL17A CRP ALB
40 volvulus of midgut 29.8 F2 CRP ATP4A ATP12A ALB
41 intestinal obstruction 29.7 IL6 CRP ATP4A ATP12A ALB
42 intracranial embolism 29.7 F3 F2 CRP ACE
43 neuromuscular disease 29.7 PABPN1 IL6 IL17A CHAT ALB
44 adult respiratory distress syndrome 29.7 IL6 F2 ACE
45 portal hypertension 29.7 F3 F2 ALB ACE
46 stroke, ischemic 29.6 IL6 F3 F2 CRP ALB ACE
47 myocarditis 29.6 PIK3C2A IL6 IL17A ALB ACE
48 lung disease 29.6 MMP8 IL6 IL17A F3 CRP ALB
49 congestive heart failure 29.5 PIK3C2A IL6 CRP ALB ACE
50 toxic shock syndrome 29.5 IL6 F3 CRP

Graphical network of the top 20 diseases related to Aspiration Pneumonia:

Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.11 ACE ALB ATP12A ATP4A CHAT CRP
2 cardiovascular system MP:0005385 10.1 ACE ALB CHAT CRP F2 F3
3 digestive/alimentary MP:0005381 9.86 ALB ATP12A ATP4A CHAT F2 IL17A
4 immune system MP:0005387 9.77 ACE ALB ATP4A CRP F2 F3
5 mortality/aging MP:0010768 9.44 ACE ALB ATP4A CHAT F2 F3

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 201)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Magnesium oxide Approved Phase 4 1309-48-4 14792
Magnesium citrate Approved Phase 4 3344-18-1
Sodium citrate Approved, Investigational Phase 4 68-04-2
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
Desflurane Approved Phase 4 57041-67-5 42113
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
Succinylcholine Approved Phase 4 306-40-1 5314
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
Remifentanil Approved Phase 4 132875-61-7 60815
15 Poractant alfa Approved Phase 4 129069-19-8
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
Ramosetron Investigational Phase 4 132036-88-5
20 Gastrointestinal Agents Phase 4
21 Cathartics Phase 4
22 Laxatives Phase 4
23 Chelating Agents Phase 4
24 Citrate Phase 4
25 Anticoagulants Phase 4
26 Anti-Ulcer Agents Phase 4
27 Picosulfate sodium Phase 4
28 Calcium, Dietary Phase 4
29 Antacids Phase 4
30 Antiemetics Phase 4
31 Anti-Infective Agents Phase 4
32 beta-Lactamase Inhibitors Phase 4
33 Antitubercular Agents Phase 4
34 Chlorhexidine gluconate Phase 4
35 Disinfectants Phase 4
36 Anti-Infective Agents, Local Phase 4
37 Amoxicillin-Potassium Clavulanate Combination Phase 4
38 Anti-Bacterial Agents Phase 4
39 Antibiotics, Antitubercular Phase 4
40 Adrenergic Agonists Phase 4
41 Adrenergic alpha-2 Receptor Agonists Phase 4
42 Vasoconstrictor Agents Phase 4
43 Anesthetics, Dissociative Phase 4
44 Analgesics, Non-Narcotic Phase 4
45 Neuromuscular Agents Phase 4
46 Neuromuscular Blocking Agents Phase 4
47 Anesthetics, General Phase 4
48 Anesthetics, Intravenous Phase 4
49 Hypnotics and Sedatives Phase 4
50 Neuromuscular Nondepolarizing Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 169)
# Name Status NCT ID Phase Drugs
1 Phase IV, Prospective, Randomized Study Comparing Preparation the Day Before and Split-dose Regimen With Sodium Picosulphate/Magnesium Citrate for Morning Colonoscopies Unknown status NCT01481714 Phase 4 Sodium picosulphate, magnesium oxid and citric acid;Sodium picosulphate/magnesium oxide and citric acid
2 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
3 The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy Completed NCT01402622 Phase 4 Propofol anesthesia
4 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
5 Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life Completed NCT02258763 Phase 4 Amoxicillin-Potassium Clavulanate Combination;Placebo
6 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Recruiting NCT02862314 Phase 4
7 Eliminating Use of Non Depolarizing Neuromuscular Blocking Agents to Reduce Postoperative Pulmonary Complications: A Multi-center, Randomized Control Trial Recruiting NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
8 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
9 Stress Assessment in Preterm Infants With Respiratory Distress Syndrome Treated or Not With an Analgesic Drug During the Traditional or the Less Invasive Method of Surfactant Therapy. Not yet recruiting NCT04073173 Phase 4 Analgesic, Opioid
10 A Randomized Placebo Controlled Trial of Low Dose Angiotensin Converting Enzyme Inhibitor to Prevent Pneumonia in Older People Who Require Tube Feeding Because of Neurological Dysphagia Terminated NCT02358642 Phase 4 Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
11 Efficacy and Cost Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Locally Advanced Head and Neck Cancer to Prevent Aspiration Pneumonia. A Randomized Phase II-III Study Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
12 Phase 2/3 Application of Botulinum Neurotoxin Type A in Salivary Glands as a Treatment of Chronic Drooling in Patients With Cerebral Palsy: A Controlled Clinical Trial. Unknown status NCT01489904 Phase 2, Phase 3
13 Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
14 Venticute in Patients With Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Ventilation, and Severe Oxygenation Impairment: A Randomized, Multinational, Multicenter, Parallel Group, Double Blind, Control Group Study Completed NCT00074906 Phase 3 Venticute
15 Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial Completed NCT02080754 Phase 3
16 A Randomised Controlled Trial of Dysphagia Therapies for Swallowing Disorders Following Stroke. Completed NCT00257764 Phase 2, Phase 3
17 The Effects of Bronchodilator Therapy On Respiratory and Autonomic Function in Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
18 Muscle Preservation and Swallow Function Following Radiotherapy: A Dose Response Study Completed NCT01279837 Phase 2, Phase 3
19 Esophageal Stent is More Effective Than Tamponade Controlling Refractory Esophageal Variceal Bleeding: a Randomized Controlled Trial Completed NCT01242280 Phase 3
20 Survey of Miglustat Therapeutic Effects on Neurological and Systemic Symptoms of Infantile Type of Sandhoff and Taysachs Diseases Recruiting NCT03822013 Phase 3 Miglustat
21 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
22 Calfactant Therapy for Direct Acute Respiratory Distress Syndrome & Direct Acute Lung Injury in Adults and Children Terminated NCT00682500 Phase 3 Calfactant;Room Air (placebo)
23 The Randomized Inhaled Nitric Oxide Study (NINOS) in Full-Term and Nearly Full-Term Infants With Hypoxic Respiratory Failure Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
24 Early Inhaled Nitric Oxide Therapy in Term and Near Term Infants With Respiratory Failure Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
25 Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Terminated NCT00016523 Phase 3 Inhaled nitric oxide;Placebo
26 Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia Terminated NCT01971320 Phase 3
27 Regular Versus Liquid Diet as the First Meal in Patients Undergoing Major Abdominal Gynecologic Cancer Operation: A Randomized Controlled Trial Withdrawn NCT00328757 Phase 3
28 Effect of Daikenchuto (TJ-100) on Intestinal Dysmotility and For the Prevention of Postoperative Paralytic Ileus in Patients Undergoing Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-Controlled Phase II Trial Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
29 Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI) Unknown status NCT02819479 Phase 2 25% Mannitol;Low-dose Intra-arterial Bevacizumab
30 Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging Completed NCT03050957 Phase 2
31 A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients Completed NCT00568698 Phase 1, Phase 2 Hydroxyurea;Placebo to match hydroxyurea
32 Effectiveness of a New Neuromuscular Electrical Stimulation (NMES) Treatment Technique (VitalStim® Therapy) in the Management of Young Infants With Severe Dysphagia: a Prospective Pilot Study Completed NCT01723358 Phase 2
33 Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia Completed NCT01085903 Phase 2 Modafinil;Placebo
34 Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia (OD). A Randomized Controlled Trial. Completed NCT01777672 Phase 2
35 Establishing Normal Swallowing and Breathing Profiles in Healthy Adults Across the Age Span Completed NCT03122145 Phase 1, Phase 2 Capsaicin
36 Aromatherapy for Postoperative Nausea and Vomiting in Children: A Single Blind Randomized Clinical Trial Completed NCT02663154 Phase 2 Aromatherapy inhaler;Saline inhaler
37 Induction of Volitional Swallowing in Chronic Dysphagia Post Stroke: A Novel Mechanism-Based Intervention Completed NCT00306501 Phase 2
38 Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts Completed NCT00773227 Phase 2
39 Cough and Swallow Rehabilitation Following Stroke Completed NCT01907321 Phase 1, Phase 2 Measures performed on all subjects
40 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial Recruiting NCT02927691 Phase 2
41 The Nutritional Supplement Phosphatidylserine in Patients With Familial Recruiting NCT02276716 Phase 2 Phosphatidylserine
42 Therapeutic Impact of tDCS on Dysphagia in the Acute Phase of Stroke / Impact thérapeutique de la tDCS Sur la Dysphagie en Phase Aigue de l'Accident Vasculaire cérébral Active, not recruiting NCT01758991 Phase 1, Phase 2
43 Effect Of Early Initiation Of Noninvasive Positive Pressure Ventilation On ICU Length Of Stay In Children With Status Asthmaticus, A Prospective Randomized Trial Withdrawn NCT01403428 Phase 2
44 A Randomised Placebo Controlled Trial to Explore the Effectiveness of Botulinum Toxin Injection at Reducing Oral Secretions and Frequency of Tracheal Suctioning in Tracheotomised Patients. Withdrawn NCT00973999 Phase 2 Botulinum Toxin
45 Comparison of GERD and the Effects of Anti-Reflux Therapy on Pulmonary Function Between Able-Bodied and SCI Individuals Unknown status NCT02584751 Phase 1 Omeprazole
46 Airway Protection Deficits According to Stimulus Type in Parkinson's Disease Completed NCT02390089 Phase 1 Capsaicin vapor
47 PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients: a Feasibility Study Not yet recruiting NCT03723291 Phase 1
48 Dynamic Laryngotracheal Separation for Aspiration. Prevention of Silent Aspiration Pneumonia During Swallowing by an Implanted Stimulator Suspended NCT00580346 Phase 1
49 Validation of a Marker for Aspiration and Endotracheal Tube Cuff Leak. Withdrawn NCT02301845 Phase 1 Diatoms Shells
50 Salivary Alpha Amylase Bronchial Measure for Early Aspiration Pneumonia Diagnosis in Patients Treated With Therapeutic Hypothermia After Out-of-hospital Cardiac Arrest. Unknown status NCT03007862

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 29

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

Lung, Brain, Colon, Testes, Heart, Tongue, Liver

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 3997)
# Title Authors PMID Year
Aspiration pneumonia and primary lung abscess: diagnosis and therapy of an aerobic or an anaerobic infection? 54 61
20477271 2007
Laryngeal Disease in Dogs and Cats: An Update. 61
31882166 2020
Echocardiography-Guided Dual-Lumen Venovenous Extracorporeal Membrane Oxygenation Cannula Placement in the ICU-A Retrospective Review. 61
31812567 2020
Individualized prediction of late-onset dysphagia in head and neck cancer survivors. 61
32031294 2020
A case of esophageal cancer with human immunodeficiency virus infection that progressed rapidly after neoadjuvant chemoradiotherapy. 61
31352645 2020
Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund. 61
31852861 2020
Unusual trifecta of infections, aspiration, and metastatic prostatic adenocarcinoma in a bronchoalveolar lavage specimen. 61
31639284 2020
Dysphagia Screening for Pneumonia Prevention in a Cancer Hospital: Results of a Quality/Safety Initiative. 61
31791195 2020
Cefepime vs. meropenem for moderate-to-severe pneumonia in patients at risk for aspiration: An open-label, randomized study. 61
31473111 2020
Association between dipeptidyl peptidase-4 inhibitor and aspiration pneumonia: disproportionality analysis using the spontaneous reporting system in Japan. 61
31822955 2020
Superior Laryngeal Nerve Palsy in Revision Anterior Cervical Surgery. 61
31246644 2020
Protecting Patient Safety and Preventing Modifiable Complications After Acute Ischemic Stroke. 61
32006035 2020
Aural stimulation with capsaicin prevented pneumonia in dementia patients. 61
31280931 2020
A cost effective custom dental guard for transoral robotic surgery. 61
30826917 2020
Motor Learning Feeding Interventions for Infants at Risk of Cerebral Palsy: A Systematic Review. 61
31069491 2020
Oropharyngeal dysphagia among patients newly discharged to nursing home care after an episode of hospital care. 61
31332709 2020
Pre-implantation genetic diagnosis in an Iranian family with a novel mutation in MUT gene. 61
32013889 2020
Per-oral endoscopic myotomy for esophageal diverticula with or without esophageal motility disorders. 61
31080116 2020
Brachycephalic airway syndrome: management of post-operative respiratory complications in 248 dogs. 61
32037517 2020
Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial. 61
31952975 2020
[Pulmonary complications in cocaine users]. 61
31883817 2020
[A case of systemic AL amyloidosis diagnosed on muscle biopsy]. 61
31852873 2020
Outcomes of enteral metallic stent in patients with pancreatic carcinoma and gastric outlet obstruction: A single center experience. 61
31171401 2020
Giant axonal neuropathy: a multicenter retrospective study with genotypic spectrum expansion. 61
31655922 2020
Spectrum of 18F-FDG Uptake in Bilateral Lung Parenchymal Diseases on PET/CT. 61
31524673 2020
Megaesophagus Is a Major Pathological Condition in Rats With a Large Deletion in the Rbm20 Gene. 61
31221019 2020
Multiple cause of death analysis in multiple sclerosis: A population-based study. 61
31932517 2020
Percutaneous endoscopic gastrostomy with jejunal extension for a post-esophagectomy gastric conduit. 61
31981087 2020
Management of dysphagia in Huntington's disease: a descriptive review. 61
31989345 2020
Total Oesophagogastric Dissociation in Neurologically Impaired Children: 18 Years' Experience and Long-Term Follow-Up. 61
31913925 2020
Aspiration pneumonia after antireflux surgery among neurologically impaired children with GERD. 61
32037217 2020
Incomplete recovery from rocuronium-induced muscle relaxation in patients with amyotrophic lateral sclerosis using sugammadex: A case report. 61
32011508 2020
Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders. 61
30996170 2020
Thrombocytopenia associated with clonidine in a case of clozapine-induced sialorrhea. 61
31942277 2020
Psychiatric inpatients subjected to physical restraint have a higher risk of deep vein thrombosis and aspiration pneumonia. 61
31734627 2020
Food bolus-forming ability predicts incidence of aspiration pneumonia in nursing home older adults: A prospective observational study. 61
31299094 2020
Association between sarcopenia and pneumonia in older people. 61
31808265 2020
Spatiotemporal clustering of in-hospital Clostridioides difficile infection. 61
32000873 2020
Endoscopic Nasoenteral Feeding Tube Fixation with Hemoclip Reduces Tube Dislodgement. 61
31367879 2020
The Mini Nutritional Assessment-Short Form as a predictor of nursing home mortality in Japan: A 30-month longitudinal study. 61
31710866 2020
Clinical characteristics of exposures to liquid laundry detergent packets. 61
31578092 2020
A Comparative Study of Two Tube Feeding Methods in Patients with Dysphagia After Stroke: A Randomized Controlled Trial. 61
31924485 2020
Pulmonary Complications of Opioid Overdose Treated With Naloxone. 61
31182316 2020
Amoxicillin-Clavulanate Dosing in the Intensive Care Unit: The Additive Effect of Renal Replacement Therapy in a Patient with Normal Kidney Function. 61
31940615 2020
Endoscopic retrieval of gastric and oesophageal foreign bodies in 52 cats. 61
31709553 2020
Rapid versus slow withdrawal of antiepileptic drugs. 61
31990368 2020
Long-Term Safety and Efficacy of Blonanserin Transdermal Patches in Japanese Patients with Schizophrenia: A 52-Week Open-Label, Multicenter Study. 61
31883082 2020
Riluzole-induced interstitial lung disease is a rare and potentially life-threatening adverse event successfully treated with high-dose steroid therapy: Case reports and review of the literature. 61
31901592 2019
Gastroesophageal reflux and respiratory diseases: does a real link exist? 61
31129955 2019
Esophageal Dysphagia in the Elderly. 61
31741211 2019

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6 ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 CHAT NM_020549.4(CHAT):c.2081C>G (p.Ser694Cys)SNV Pathogenic 523529 rs201439531 10:50872926-50872926 10:49664880-49664880
2 CHAT NM_020549.4(CHAT):c.1061C>T (p.Thr354Met)SNV Conflicting interpretations of pathogenicity 523528 rs769234940 10:50835781-50835781 10:49627735-49627735

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

Pathways related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
Show member pathways
11.59 IL6 F2 CRP ALB
2 10.48 MYH2 ITGAM IL6

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 TAC1 NPC2 MMP8 IL6 IL17A F3
2 extracellular space GO:0005615 9.4 TAC1 NPC2 MMP8 ITGAM IL6 IL17A

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of neuroinflammatory response GO:0150078 9.37 MMP8 IL6
2 regulation of neuroinflammatory response GO:0150077 9.32 MMP8 IL6
3 negative regulation of lipid storage GO:0010888 9.26 IL6 CRP
4 neutrophil mediated immunity GO:0002446 9.16 IL6 ACE
5 regulation of microglial cell activation GO:1903978 8.96 MMP8 IL6
6 acute-phase response GO:0006953 8.8 IL6 F2 CRP

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Aspiration Pneumonia

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
Loading form....