MCID: ASP007
MIFTS: 46

Aspiration Pneumonia

Categories: Gastrointestinal diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 77 30 6 15 74
Pneumonia, Aspiration 45 17
Aspiration Pneumonitis 74
Pneumonia Aspiration 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0050152
MeSH 45 D011015
SNOMED-CT 69 47839005
ICD10 34 J69.0

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to aspiration pneumonitis and megaesophagus. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase). The drugs Fentanyl and Desflurane have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotypes are homeostasis/metabolism and renal/urinary system

Wikipedia : 77 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 181)
# Related Disease Score Top Affiliating Genes
1 aspiration pneumonitis 32.8 ATP12A ATP4A
2 megaesophagus 11.5
3 oculopharyngeal muscular dystrophy 11.2
4 orofaciodigital syndrome ix 11.2
5 spastic paraplegia 2, x-linked 11.2
6 spinal and bulbar muscular atrophy, x-linked 1 11.2
7 eclampsia 11.2
8 anaerobic pneumonia 11.2
9 corticobasal degeneration 11.2
10 fukuyama type muscular dystrophy 11.2
11 microgastria limb reduction defect 11.2
12 x-linked dystonia-parkinsonism/lubag 11.2
13 pneumonia 11.1
14 dysphagia 10.4
15 leukocyte adhesion deficiency, type i 10.3 IL17A ITGAM
16 chronic inflammatory demyelinating polyradiculoneuropathy 10.3 ALB IL17A
17 polyradiculoneuropathy 10.3 ALB IL17A
18 autoimmune optic neuritis 10.2 IL17A ITGAM
19 fungal esophagitis 10.2 ATP12A ATP4A
20 diclofenac allergy 10.2 ATP12A ATP4A
21 gastroduodenal crohn's disease 10.2 ATP12A ATP4A
22 neonatal candidiasis 10.2 ATP12A ATP4A
23 photoallergic dermatitis 10.2 ATP12A ATP4A
24 squamous papillomatosis 10.2 ATP12A ATP4A
25 toxic megacolon 10.2 ATP12A ATP4A
26 gastrointestinal neuroendocrine benign tumor 10.2 ATP12A ATP4A
27 gastric antral vascular ectasia 10.2 ATP12A ATP4A
28 granulomatous gastritis 10.2 ATP12A ATP4A
29 esophageal candidiasis 10.2 ATP12A ATP4A
30 gastric neuroendocrine neoplasm 10.2 ATP12A ATP4A
31 acute laryngitis 10.2 ATP12A ATP4A
32 laryngitis 10.2 ATP12A ATP4A
33 duodenitis 10.2 ATP12A ATP4A
34 rumination disorder 10.2 ATP12A ATP4A
35 active peptic ulcer disease 10.2 ATP12A ATP4A
36 congenital disorder of deglycosylation 10.2 ATP12A ATP4A
37 bladder calculus 10.2 ATP12A ATP4A
38 ischemic neuropathy 10.2 ATP12A ATP4A
39 bile reflux 10.2 ATP12A ATP4A
40 peptic esophagitis 10.2 ATP12A ATP4A
41 hernia, hiatus 10.2 ATP12A ATP4A
42 postsurgical hypothyroidism 10.2 ATP12A ATP4A
43 lymphocytic colitis 10.2 ATP12A ATP4A
44 clostridium difficile colitis 10.2 ATP12A ATP4A
45 diarrhea 1, secretory chloride, congenital 10.2 ATP12A ATP4A
46 esophagitis, eosinophilic, 1 10.2 ATP12A ATP4A
47 microscopic colitis 10.2 ATP12A ATP4A
48 laryngeal tuberculosis 10.2 ATP12A ATP4A
49 chronic laryngitis 10.2 ATP12A ATP4A
50 eosinophilic gastritis 10.2 ATP12A ATP4A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 ALB ATP12A ATP4A CHAT CHST8 IL17A
2 renal/urinary system MP:0005367 9.02 ALB ATP12A IL17A TAC1 TRPV1

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 195)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 437-38-7 3345
2
Desflurane Approved Phase 4 57041-67-5 42113
3
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
4
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
5
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 2713 9552079
6
Ampicillin Approved, Vet_approved Phase 4,Phase 3 69-53-4 6249
7
Sulbactam Approved Phase 4,Phase 3 68373-14-8
8
tannic acid Approved Phase 4,Not Applicable 1401-55-4
9
Atracurium Approved, Experimental, Investigational Phase 4 64228-79-1 47319
10
Cisatracurium Approved Phase 4 96946-41-7
11
Succinylcholine Approved Phase 4 306-40-1 5314
12
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
13
Neostigmine Approved, Vet_approved Phase 4,Not Applicable 59-99-4 4456
14
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
15
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
16 Ramosetron Investigational Phase 4 132036-88-5
17 Chlorine dioxide Investigational Phase 4 10049-04-4
18 Anesthetics Phase 4,Phase 3,Not Applicable
19 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Not Applicable
20 Bronchodilator Agents Phase 4,Phase 3,Phase 1,Not Applicable
21 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Not Applicable
22 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Not Applicable
23 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1
25 Autonomic Agents Phase 4,Phase 3,Phase 1,Not Applicable
26 Protective Agents Phase 4,Phase 3,Phase 1
27 Hypnotics and Sedatives Phase 4,Phase 3
28 Central Nervous System Depressants Phase 4,Phase 3,Not Applicable
29 Antiemetics Phase 4,Not Applicable
30 Anesthetics, General Phase 4,Phase 3
31 Anesthetics, Intravenous Phase 4,Phase 3
32 Anti-Infective Agents, Local Phase 4,Not Applicable
33 Chlorhexidine gluconate Phase 4,Not Applicable
34 Dermatologic Agents Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable
35 Disinfectants Phase 4,Not Applicable
36 Cholinergic Antagonists Phase 4
37 Neuromuscular Nondepolarizing Agents Phase 4
38 Neuromuscular Depolarizing Agents Phase 4
39 Neuromuscular Agents Phase 4,Phase 3,Phase 1,Phase 2
40 Neuromuscular Blocking Agents Phase 4,Not Applicable
41 Cholinergic Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
42 Adrenergic Agonists Phase 4,Not Applicable
43 Adrenergic alpha-Agonists Phase 4,Not Applicable
44 Adrenergic Agents Phase 4,Not Applicable
45 Cholinesterase Inhibitors Phase 4,Not Applicable
46 HIV Protease Inhibitors Phase 4,Not Applicable
47
protease inhibitors Phase 4,Not Applicable
48 Analgesics, Non-Narcotic Phase 4
49 Analgesics Phase 4
50 Adrenergic alpha-2 Receptor Agonists Phase 4

Interventional clinical trials:

(show top 50) (show all 148)
# Name Status NCT ID Phase Drugs
1 The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy Completed NCT01402622 Phase 4 Propofol anesthesia
2 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
3 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
4 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications Completed NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
5 Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques Completed NCT01463540 Phase 4
6 Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders Completed NCT03533335 Phase 4
7 Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery Completed NCT02635542 Phase 4 Succinylcholine;Cisatracurium
8 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Recruiting NCT02862314 Phase 4
9 Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation Recruiting NCT02958150 Phase 4 Dexmedetomidine
10 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
11 Avoiding Neuromuscular Blockers to Reduce Complications Not yet recruiting NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
12 Drug to Prevent Pneumonia in the Tube Fed Terminated NCT02358642 Phase 4 Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
13 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
14 Pre Hospital Evaluation of Video Laryngoscopy Withdrawn NCT01374061 Phase 4
15 Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
16 SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition Unknown status NCT02175979 Phase 3
17 BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
18 Sellick Interest in Rapid Sequence Induction Completed NCT02080754 Phase 3
19 Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults Completed NCT02610868 Phase 3 MYOBLOC
20 Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in Japan Recruiting NCT03336645 Phase 3 SHP615
21 Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting Recruiting NCT03336450 Phase 3 SHP615;MHOS/SHP615
22 Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia Terminated NCT01971320 Phase 3
23 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
24 A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor Terminated NCT02377466 Phase 3 Retosiban IV infusion;Placebo IV infusion
25 A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour Terminated NCT02292771 Phase 3 Retosiban;Atosiban;Placebo matching retosiban;Placebo matching atosiban
26 Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
27 Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
28 Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
29 Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea Unknown status NCT01812993 Phase 2
30 Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia Completed NCT01777672 Phase 2
31 Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging Completed NCT03050957 Phase 2
32 Cough and Swallow Rehab Following Stroke Completed NCT01907321 Phase 1, Phase 2 Measures performed on all subjects
33 Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts Completed NCT00773227 Phase 2
34 Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease Completed NCT01479127 Phase 2 ABT-SLV187;Oral Levodopa/Carbidopa
35 Dysport for the Treatment of OMD Completed NCT01921270 Phase 1, Phase 2 Low Dose - AbobotulinumtoxinA
36 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial Recruiting NCT02927691 Phase 2
37 Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer Recruiting NCT03224000 Phase 2
38 Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation Active, not recruiting NCT01758991 Phase 1, Phase 2
39 Proof of Concept (POC) in Patients With Ischaemic Stroke Terminated NCT01808261 Phase 2 GSK249320 100/mg;Placebo
40 GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals Unknown status NCT02584751 Phase 1 Omeprazole
41 Cough According to Stimulus Type in PD Completed NCT02390089 Phase 1 Capsaicin vapor
42 Fecal Microbiota Transplantation for Treatment of Refractory Graft Versus Host Disease-a Pilot Study Not yet recruiting NCT03549676 Phase 1
43 Dynamic Laryngotracheal Separation for Aspiration Suspended NCT00580346 Phase 1
44 Validation of Aspiration Markers Withdrawn NCT02301845 Phase 1 Diatoms Shells
45 Bronchial Alpha Amylase as a Marker for Early Aspiration Pneumonia in Therapeutic Hypothermia. Unknown status NCT03007862
46 Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation Unknown status NCT03108430
47 Pre-Procedural Fasting in Cardiac Intervention Unknown status NCT02562638 Not Applicable
48 Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment Unknown status NCT02243722
49 Laparoscopy Heller Myotomy With Fundoplication Associated Versus Peroral Endoscopic Myotomy (POEM) Unknown status NCT02138643 Not Applicable
50 Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy Unknown status NCT02983175 Not Applicable

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 30

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

42
Lung, Colon, Testes, Liver, Cortex, Brain, Neutrophil

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 576)
# Title Authors Year
1
The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit. ( 29603057 )
2019
2
Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature: Reply. ( 30119837 )
2019
3
Dysphagia and aspiration pneumonia in elderly hospitalization stroke patients: Risk factors, cerebral infarction area comparison. ( 30223382 )
2019
4
Diagnostic Accuracy of Procalcitonin for Early Aspiration Pneumonia in Critically Ill Patients with Coma: A Prospective Study. ( 30267280 )
2019
5
Effects of preoperative cisapride on postoperative aspiration pneumonia in dogs with laryngeal paralysis. ( 30387153 )
2019
6
Aspiration pneumonia and pneumonitis: a spectrum of infectious/noninfectious diseases affecting the lung. ( 30676341 )
2019
7
Aspiration Pneumonia. ( 30763196 )
2019
8
Aspiration Pneumonia in Older Adults. ( 30794136 )
2019
9
Clinical and radiographic findings in cats with aspiration pneumonia: retrospective evaluation of 28 cases. ( 30843218 )
2019
10
Meconium aspiration pneumonia and otitis media in two goat kids. ( 30852957 )
2019
11
The Mortality and the Risk of Aspiration Pneumonia Related with Dysphagia in Stroke Patients. ( 30857927 )
2019
12
Antimicrobial susceptibilities of clinical isolates of the anaerobic bacteria which can cause aspiration pneumonia. ( 30951830 )
2019
13
Proportion of Aspiration Pneumonia Cases Among Patients With Community-Acquired Pneumonia: A Single-Center Study in Korea. ( 31072078 )
2019
14
Long-Term Mortality and Prognostic Factors in Aspiration Pneumonia. ( 31080159 )
2019
15
Could Polymerase Chain Reaction-Based Methods Differentiate Pneumonitis From Bacterial Aspiration Pneumonia? ( 29252957 )
2018
16
Variation in the Diagnosis of Aspiration Pneumonia and Association with Hospital Pneumonia Outcomes. ( 29298090 )
2018
17
Relationship of aspiration pneumonia to cognitive impairment and oral condition: a cross-sectional study. ( 29388021 )
2018
18
Silent aspiration predicts mortality in older adults with aspiration pneumonia admitted to acute hospitals. ( 29388314 )
2018
19
A Randomized Controlled Trial to Investigate the Effectiveness of the Prevention of Aspiration Pneumonia Using Recommendations for Swallowing Care Guided by Ultrasound Examination. ( 29439537 )
2018
20
Using oral health assessment to predict aspiration pneumonia in older adults. ( 29446124 )
2018
21
Project SITUP: An Interdisciplinary Quality Improvement Initiative to Reduce Aspiration Pneumonia. ( 29466260 )
2018
22
ASPIRATION PNEUMONIA IN TWO TIBETAN YAK BULLS ( BOS GRUNNIENS) AS A COMPLICATION OF KETAMINE-XYLAZINE-BUTORPHANOL ANESTHESIA FOR RECUMBENT CASTRATION. ( 29517446 )
2018
23
The importance of oral health to prevent aspiration pneumonia. ( 29531209 )
2018
24
Aspiration Pneumonia as a Cause of Death in Critically Ill Patients with Dysphagia After Extubation. ( 29538126 )
2018
25
Bacteriological testing and recurrence prevention efforts in the diagnosis and treatment of nursing- and healthcare-associated pneumonia and aspiration pneumonia: A questionnaire survey of hospitals across Japan. ( 29548653 )
2018
26
Pre-stroke undiagnosed dysphagia lusoria as a rare cause of aspiration pneumonia with respiratory failure in a stroke patient. ( 29552342 )
2018
27
Comparison of Videofluoroscopic Swallowing Study and Radionuclide Salivagram for Aspiration Pneumonia in Children With Swallowing Difficulty. ( 29560324 )
2018
28
Aspiration Pneumonia and Related Syndromes. ( 29730088 )
2018
29
Erratum to "The possible protective role of pumpkin seed oil in an animal model of acid aspiration pneumonia: Light and electron microscopic study Acta Histochemica 119 (2017) 161-171". ( 29764621 )
2018
30
Effect of starting oral intake on weekends on the clinical course of patients with aspiration pneumonia. ( 29780243 )
2018
31
Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems. ( 29790300 )
2018
32
Assessment of aspiration pneumonia using the Anticholinergic Risk Scale. ( 29856113 )
2018
33
Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease. ( 29874285 )
2018
34
Repetitive Aspiration Pneumonia Caused by Basilar Impression. ( 29877294 )
2018
35
Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study. ( 29932081 )
2018
36
Determining Peak Cough Flow Cutoff Values to Predict Aspiration Pneumonia Among Patients With Dysphagia Using the Citric Acid Reflexive Cough Test. ( 29981313 )
2018
37
Incidence of aspiration pneumonia during hospitalization in Japanese hospitalized cases did not increase whereas concern factors were exacerbated in a time-dependent manner: analysis of Diagnosis Procedure Combination (DPC) data. ( 30087546 )
2018
38
Asymptomatic dysphagia causing recurrent aspiration pneumonia. ( 30131410 )
2018
39
Predictors for achieving oral intake in older patients with aspiration pneumonia: Videofluoroscopic evaluation of swallowing function. ( 30168244 )
2018
40
Retrospective analysis of incidence, clinical features, potential risk factors, and prognostic indicators for aspiration pneumonia in three brachycephalic dog breeds. ( 30211637 )
2018
41
A novel semi-solidifying liquid formula via the nasogastric route to maintain enteral nutrition in the event of recurrent aspiration pneumonia: A case report. ( 30214747 )
2018
42
Use of prophylactic antibiotics in aspiration pneumonia. ( 30321306 )
2018
43
Antibacterial treatment of aspiration pneumonia in older people: a systematic review. ( 30464429 )
2018
44
Clinical significance and efficacy analysis of atorvastatin in the treatment of patients with cerebral infarction and aspiration pneumonia. ( 30542469 )
2018
45
Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis. ( 30556343 )
2018
46
Observations from a pediatric dysphagia clinic: Characteristics of children at risk of aspiration pneumonia. ( 30582163 )
2018
47
Different clinical predictors of aspiration pneumonia in dysphagic stroke patients related to stroke lesion: A STROBE-complaint retrospective study. ( 30593222 )
2018
48
The impact of aspiration pneumonia and nasogastric feeding on clinical outcomes in stroke patients: A retrospective cohort study. ( 28618137 )
2018
49
Diagnostic performance of initial serum albumin level for predicting in-hospital mortality among aspiration pneumonia patients. ( 28666627 )
2018
50
The occurrence of aspiration pneumonia after emergency endotracheal intubation. ( 28760377 )
2018

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CHAT NM_020549.4(CHAT): c.1061C> T (p.Thr354Met) single nucleotide variant Conflicting interpretations of pathogenicity rs769234940 GRCh37 Chromosome 10, 50835781: 50835781
2 CHAT NM_020549.4(CHAT): c.1061C> T (p.Thr354Met) single nucleotide variant Conflicting interpretations of pathogenicity rs769234940 GRCh38 Chromosome 10, 49627735: 49627735
3 CHAT NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys) single nucleotide variant Pathogenic rs201439531 GRCh37 Chromosome 10, 50872926: 50872926
4 CHAT NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys) single nucleotide variant Pathogenic rs201439531 GRCh38 Chromosome 10, 49664880: 49664880

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

GO Terms for Aspiration Pneumonia

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.46 ATP12A ATP4A
2 cellular response to nerve growth factor stimulus GO:1990090 9.43 TAC1 TRPV1
3 ATP hydrolysis coupled proton transport GO:0015991 9.4 ATP12A ATP4A
4 response to pain GO:0048265 9.37 TAC1 TRPV1
5 microglial cell activation GO:0001774 9.32 ITGAM TRPV1
6 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
8 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
9 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Aspiration Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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