MCID: ASP007
MIFTS: 46

Aspiration Pneumonia

Categories: Gastrointestinal diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 76 29 6 15 73
Aspiration Pneumonitis 73
Pneumonia, Aspiration 44
Pneumonia Aspiration 55

Classifications:



External Ids:

Disease Ontology 12 DOID:0050152
ICD10 33 J69.0
MeSH 44 D011015
SNOMED-CT 68 47839005

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as aspiration pneumonitis, is related to aspiration pneumonitis and megaesophagus. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways is Ion channel transport. The drugs Propofol and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotype is homeostasis/metabolism.

Wikipedia : 76 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
# Related Disease Score Top Affiliating Genes
1 aspiration pneumonitis 32.4 ATP12A ATP4A
2 megaesophagus 11.5
3 oculopharyngeal muscular dystrophy 11.1
4 orofaciodigital syndrome ix 11.1
5 spastic paraplegia 2, x-linked 11.1
6 spinal and bulbar muscular atrophy, x-linked 1 11.1
7 eclampsia 11.1
8 anaerobic pneumonia 11.1
9 corticobasal degeneration 11.1
10 fukuyama type muscular dystrophy 11.1
11 microgastria limb reduction defect 11.1
12 x-linked dystonia-parkinsonism/lubag 11.1
13 pneumonia 11.0
14 dysphagia 10.4
15 leiomyoma cutis 10.2 TAC1 TRPV1
16 leukocyte adhesion deficiency, type i 10.2 IL17A ITGAM
17 autoimmune optic neuritis 10.2 IL17A ITGAM
18 trigeminal nerve disease 10.1 TAC1 TRPV1
19 burning mouth syndrome 10.1 TAC1 TRPV1
20 mononeuropathy 10.1 TAC1 TRPV1
21 dental pulp disease 10.1 TAC1 TRPV1
22 chronic inflammatory demyelinating polyradiculoneuropathy 10.1 ALB IL17A
23 polyradiculoneuropathy 10.1 ALB IL17A
24 central nervous system disease 10.1 CHAT IL17A TRPV1
25 cardiovascular organ benign neoplasm 10.1 TAC1 TRPV1
26 benign perivascular tumor 10.1 TAC1 TRPV1
27 bronchial disease 10.1 IL17A TAC1 TRPV1
28 pain agnosia 10.1 TAC1 TRPV1
29 autonomic nervous system disease 10.1 ALB TAC1
30 agnosia 10.0 TAC1 TRPV1
31 nervous system disease 10.0 ALB CHAT TRPV1
32 lung abscess 10.0
33 immune system disease 10.0 ALB IL17A TRPV1
34 intestinal disease 10.0 ALB IL17A TRPV1
35 respiratory system disease 10.0 ALB IL17A TRPV1
36 nasal cavity disease 10.0 TAC1 TRPV1
37 somatoform disorder 10.0 TAC1 TRPV1
38 peripheral nervous system disease 10.0 ALB TAC1 TRPV1
39 stroke, ischemic 10.0
40 cerebrovascular disease 10.0
41 achalasia 10.0
42 nose disease 10.0 TAC1 TRPV1
43 meningoencephalitis 10.0 ALB TAC1
44 drug allergy 9.9 ALB ATP12A
45 fungal esophagitis 9.9 ATP12A ATP4A
46 diclofenac allergy 9.9 ATP12A ATP4A
47 gastroduodenal crohn's disease 9.9 ATP12A ATP4A
48 neonatal candidiasis 9.9 ATP12A ATP4A
49 photoallergic dermatitis 9.9 ATP12A ATP4A
50 squamous papillomatosis 9.9 ATP12A ATP4A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 ALB ATP12A ATP4A CHAT CHST8 IL17A

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 190)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 437-38-7 3345
3
Desflurane Approved Phase 4 57041-67-5 42113
4
Remifentanil Approved Phase 4 132875-61-7 60815
5
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 2713 9552079
6
Sulbactam Approved Phase 4,Phase 3 68373-14-8
7
Ampicillin Approved, Vet_approved Phase 4,Phase 3 69-53-4 6249
8
Neostigmine Approved, Vet_approved Phase 4,Not Applicable 59-99-4 4456
9
Salmon Calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
10
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
11
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
12 Ramosetron Investigational Phase 4 132036-88-5
13 Chlorine dioxide Investigational Phase 4 10049-04-4
14
Calcitonin gene-related peptide Investigational Phase 4 83652-28-2
15 Central Nervous System Depressants Phase 4,Phase 3,Not Applicable
16 Anesthetics Phase 4,Phase 3,Not Applicable
17 Anesthetics, General Phase 4,Phase 3
18 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Not Applicable
19 Anti-Infective Agents, Local Phase 4,Not Applicable
20 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Not Applicable
21 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3
22 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1
23 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Bronchodilator Agents Phase 4,Phase 1,Not Applicable
25 Autonomic Agents Phase 4,Phase 1,Not Applicable
26 Protective Agents Phase 4,Phase 1
27 Hypnotics and Sedatives Phase 4,Phase 3
28 Antiemetics Phase 4,Not Applicable
29 Anesthetics, Intravenous Phase 4,Phase 3
30 Dermatologic Agents Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable
31 Chlorhexidine gluconate Phase 4,Not Applicable
32 Disinfectants Phase 4,Not Applicable
33 Adrenergic Agonists Phase 4,Not Applicable
34 Adrenergic alpha-Agonists Phase 4,Not Applicable
35 Adrenergic Agents Phase 4,Not Applicable
36 Cholinergic Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
37 Cholinesterase Inhibitors Phase 4,Not Applicable
38 HIV Protease Inhibitors Phase 4,Not Applicable
39
protease inhibitors Phase 4,Not Applicable
40 Neuromuscular Blocking Agents Phase 4,Not Applicable
41 Bone Density Conservation Agents Phase 4
42 calcitonin Phase 4
43 Analgesics Phase 4
44 Analgesics, Non-Narcotic Phase 4
45 Adrenergic alpha-2 Receptor Agonists Phase 4
46 Adjuvants, Anesthesia Phase 4,Phase 3
47 Cholinergic Antagonists Phase 4
48 Muscarinic Antagonists Phase 4
49
Glycopyrrolate Phase 4 596-51-0 3494
50 Antihypertensive Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 134)
# Name Status NCT ID Phase Drugs
1 The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy Completed NCT01402622 Phase 4 Propofol anesthesia
2 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
3 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
4 Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques Completed NCT01463540 Phase 4
5 Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders Completed NCT03533335 Phase 4
6 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Recruiting NCT02862314 Phase 4
7 Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation Recruiting NCT02958150 Phase 4 Dexmedetomidine
8 Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications Active, not recruiting NCT02644876 Phase 4 Penehyclidine inhalation;Placebo inhalation
9 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
10 Drug to Prevent Pneumonia in the Tube Fed Terminated NCT02358642 Phase 4 Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
11 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
12 Pre Hospital Evaluation of Video Laryngoscopy Withdrawn NCT01374061 Phase 4
13 Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
14 BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
15 Sellick Interest in Rapid Sequence Induction Completed NCT02080754 Phase 3
16 Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults Completed NCT02610868 Phase 3 MYOBLOC
17 Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in Japan Recruiting NCT03336645 Phase 3 SHP615
18 Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting Recruiting NCT03336450 Phase 3 SHP615;MHOS/SHP615
19 SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition Active, not recruiting NCT02175979 Phase 3
20 Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia Terminated NCT01971320 Phase 3
21 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
22 A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor Terminated NCT02377466 Phase 3 Retosiban IV infusion;Placebo IV infusion
23 A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour Terminated NCT02292771 Phase 3 Retosiban;Atosiban;Placebo matching retosiban;Placebo matching atosiban
24 Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
25 Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea Unknown status NCT01812993 Phase 2
26 Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia Completed NCT01777672 Phase 2
27 Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging Completed NCT03050957 Phase 2
28 Cough and Swallow Rehab Following Stroke Completed NCT01907321 Phase 1, Phase 2 Measures performed on all subjects
29 Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts Completed NCT00773227 Phase 2
30 Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease Completed NCT01479127 Phase 2 ABT-SLV187;Oral Levodopa/Carbidopa
31 Dysport for the Treatment of OMD Completed NCT01921270 Phase 1, Phase 2 Low Dose - AbobotulinumtoxinA
32 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial Recruiting NCT02927691 Phase 2
33 Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer Recruiting NCT03224000 Phase 2
34 Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation Active, not recruiting NCT01758991 Phase 1, Phase 2
35 Proof of Concept (POC) in Patients With Ischaemic Stroke Terminated NCT01808261 Phase 2 GSK249320 100/mg;Placebo
36 GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals Unknown status NCT02584751 Phase 1 Omeprazole
37 Cough According to Stimulus Type in PD Active, not recruiting NCT02390089 Phase 1 Capsaicin vapor
38 Fecal Microbiota Transplantation for Treatment of Refractory Graft Versus Host Disease-a Pilot Study Not yet recruiting NCT03549676 Phase 1
39 Dynamic Laryngotracheal Separation for Aspiration Suspended NCT00580346 Phase 1
40 Pre-Procedural Fasting in Cardiac Intervention Unknown status NCT02562638 Not Applicable
41 Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment Unknown status NCT02243722
42 Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy Unknown status NCT02983175 Not Applicable
43 Comparison of Ultrasound and Videofluoroscopic Imaging Techniques in Diagnosing Dysphagia in Stroke Patients Unknown status NCT01249300
44 Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy Unknown status NCT00536952 Early Phase 1 Pulmozyme;Placebo
45 EtCO2 Monitoring in Acute Self-poisoning Unknown status NCT01800123
46 Mechanical Ventilation During Cardiac Surgery Unknown status NCT02090205 Not Applicable
47 Minimal-Massive Intervention in Elderly Patients With Dysphagia Unknown status NCT02396992 Not Applicable
48 General Anesthesia for Endovascular Thrombectomy; A Pilot Study. Unknown status NCT02639806 Sevoflurane;Lidocaine
49 The Research of the Evaluation of Clinical Procedures in Gastroesophageal Varices in Patients With Liver Cirrhosis Unknown status NCT01592578 Not Applicable
50 The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on the Incidence of Aspiration Pneumonia and Postoperative Length of Stay Completed NCT02858596 Not Applicable

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 29

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

41
Lung, Colon, Testes, Brain, Tongue, Liver, Cortex

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 571)
# Title Authors Year
1
Effect of starting oral intake on weekends on the clinical course of patients with aspiration pneumonia. ( 29780243 )
2018
2
A Randomized Controlled Trial to Investigate the Effectiveness of the Prevention of Aspiration Pneumonia Using Recommendations for Swallowing Care Guided by Ultrasound Examination. ( 29439537 )
2018
3
Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems. ( 29790300 )
2018
4
Using oral health assessment to predict aspiration pneumonia in older adults. ( 29446124 )
2018
5
Comparison of Videofluoroscopic Swallowing Study and Radionuclide Salivagram for Aspiration Pneumonia in Children With Swallowing Difficulty. ( 29560324 )
2018
6
Pre-stroke undiagnosed dysphagia lusoria as a rare cause of aspiration pneumonia with respiratory failure in a stroke patient. ( 29552342 )
2018
7
Bacteriological testing and recurrence prevention efforts in the diagnosis and treatment of nursing- and healthcare-associated pneumonia and aspiration pneumonia: A questionnaire survey of hospitals across Japan. ( 29548653 )
2018
8
Aspiration Pneumonia as a Cause of Death in Critically Ill Patients with Dysphagia After Extubation. ( 29538126 )
2018
9
Variation in the Diagnosis of Aspiration Pneumonia and Association with Hospital Pneumonia Outcomes. ( 29298090 )
2018
10
Silent aspiration predicts mortality in older adults with aspiration pneumonia admitted to acute hospitals. ( 29388314 )
2018
11
Could Polymerase Chain Reaction-Based Methods Differentiate Pneumonitis From Bacterial Aspiration Pneumonia? ( 29252957 )
2018
12
Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease. ( 29874285 )
2018
13
Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study. ( 29932081 )
2018
14
Relationship of aspiration pneumonia to cognitive impairment and oral condition: a cross-sectional study. ( 29388021 )
2018
15
Determining peak cough flow cut-off values to predict aspiration pneumonia among patients with dysphagia using the citric acid reflexive cough test. ( 29981313 )
2018
16
The importance of oral health to prevent aspiration pneumonia. ( 29531209 )
2018
17
Repetitive Aspiration Pneumonia Caused by Basilar Impression. ( 29877294 )
2018
18
Assessment of aspiration pneumonia using the Anticholinergic Risk Scale. ( 29856113 )
2018
19
Aspiration Pneumonia and Related Syndromes. ( 29730088 )
2018
20
The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit. ( 29603057 )
2018
21
Project SITUP: An Interdisciplinary Quality Improvement Initiative to Reduce Aspiration Pneumonia. ( 29466260 )
2018
22
ASPIRATION PNEUMONIA IN TWO TIBETAN YAK BULLS ( BOS GRUNNIENS) AS A COMPLICATION OF KETAMINE-XYLAZINE-BUTORPHANOL ANESTHESIA FOR RECUMBENT CASTRATION. ( 29517446 )
2018
23
Antibacterial treatment of aspiration pneumonia in older people: a systematic review. ( 30464429 )
2018
24
Clinical significance and efficacy analysis of atorvastatin in the treatment of patients with cerebral infarction and aspiration pneumonia. ( 30542469 )
2018
25
Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis. ( 30556343 )
2018
26
The impact of aspiration pneumonia and nasogastric feeding on clinical outcomes in stroke patients: A retrospective cohort study. ( 28618137 )
2018
27
Erratum to "The possible protective role of pumpkin seed oil in an animal model of acid aspiration pneumonia: Light and electron microscopic study Acta Histochemica 119 (2017) 161-171". ( 29764621 )
2018
28
Incidence of aspiration pneumonia during hospitalization in Japanese hospitalized cases did not increase whereas concern factors were exacerbated in a time-dependent manner: analysis of Diagnosis Procedure Combination (DPC) data. ( 30087546 )
2018
29
Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature: Reply. ( 30119837 )
2018
30
Asymptomatic dysphagia causing recurrent aspiration pneumonia. ( 30131410 )
2018
31
Predictors for achieving oral intake in older patients with aspiration pneumonia: Videofluoroscopic evaluation of swallowing function. ( 30168244 )
2018
32
Retrospective analysis of incidence, clinical features, potential risk factors, and prognostic indicators for aspiration pneumonia in three brachycephalic dog breeds. ( 30211637 )
2018
33
A novel semi-solidifying liquid formula via the nasogastric route to maintain enteral nutrition in the event of recurrent aspiration pneumonia: A case report. ( 30214747 )
2018
34
Dysphagia and aspiration pneumonia in elderly hospitalization stroke patients: Risk factors, cerebral infarction area comparison. ( 30223382 )
2018
35
Diagnostic Accuracy of Procalcitonin for Early Aspiration Pneumonia in Critically Ill Patients with Coma: A Prospective Study. ( 30267280 )
2018
36
Use of prophylactic antibiotics in aspiration pneumonia. ( 30321306 )
2018
37
Effects of preoperative cisapride on postoperative aspiration pneumonia in dogs with laryngeal paralysis. ( 30387153 )
2018
38
Diagnostic performance of initial serum albumin level for predicting in-hospital mortality among aspiration pneumonia patients. ( 28666627 )
2017
39
Effects of aspiration pneumonia on the intensive care requirements and in-hospital mortality of hospitalised patients with acute cerebrovascular disease. ( 28883847 )
2017
40
Percutaneous endoscopic gastrostomy for aspiration pneumonia: A 10-year single-center experience. ( 28427747 )
2017
41
Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from aspiration pneumonia. ( 28024728 )
2017
42
Antipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions: A Cohort Study. ( 29095482 )
2017
43
Rehabilitative management for aspiration pneumonia in elderly patients. ( 29263982 )
2017
44
Aspiration Pneumonia in Carbon Monoxide Poisoning Patients with Loss of Consciousness: Prevalence, Outcomes, and Risk Factors. ( 28803137 )
2017
45
Preoperative Pulmonary Function Tests Predict Aspiration Pneumonia After Gastric Endoscopic Submucosal Dissection. ( 28879570 )
2017
46
National Trends in Admission for Aspiration Pneumonia in the United States, 2002-2012. ( 28272915 )
2017
47
Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature. ( 28992957 )
2017
48
Ability of High-Resolution Manometry to Determine Feeding Method and to Predict Aspiration Pneumonia in Patients With Dysphagia. ( 28374817 )
2017
49
The occurrence of aspiration pneumonia after emergency endotracheal intubation. ( 28760377 )
2017
50
Efficacy of a New Post-Mouthwash Intervention (Wiping Plus Oral Nutritional Supplements) for Preventing Aspiration Pneumonia in Elderly People: A Multicenter, Randomized, Comparative Trial. ( 29183037 )
2017

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CHAT NM_020549.4(CHAT): c.1061C> T (p.Thr354Met) single nucleotide variant Conflicting interpretations of pathogenicity rs769234940 GRCh37 Chromosome 10, 50835781: 50835781
2 CHAT NM_020549.4(CHAT): c.1061C> T (p.Thr354Met) single nucleotide variant Conflicting interpretations of pathogenicity rs769234940 GRCh38 Chromosome 10, 49627735: 49627735
3 CHAT NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys) single nucleotide variant Pathogenic rs201439531 GRCh37 Chromosome 10, 50872926: 50872926
4 CHAT NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys) single nucleotide variant Pathogenic rs201439531 GRCh38 Chromosome 10, 49664880: 49664880

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

Pathways related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.42 ATP12A ATP4A GLRA1 TRPV1

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.92 GLRA1 IL17A ITGAM TRPV1

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.8 ATP12A ATP4A GLRA1 TRPV1
2 potassium ion import across plasma membrane GO:1990573 9.48 ATP12A ATP4A
3 cellular response to nerve growth factor stimulus GO:1990090 9.46 TAC1 TRPV1
4 potassium ion import GO:0010107 9.43 ATP12A ATP4A
5 ATP hydrolysis coupled proton transport GO:0015991 9.4 ATP12A ATP4A
6 response to pain GO:0048265 9.37 TAC1 TRPV1
7 microglial cell activation GO:0001774 9.32 ITGAM TRPV1
8 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
9 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
10 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
11 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Aspiration Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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