Aspiration Pneumonia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ASP007 MIFTS: 46	Aspiration Pneumonia Categories: Gastrointestinal diseases, Respiratory diseases
Genes Variations Tissues Related diseases Publications Drugs Expand all tables

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Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia ¹² ⁷⁷ ³⁰ ⁶ ¹⁵ ⁷⁴

Pneumonia, Aspiration ⁴⁵ ¹⁷

Aspiration Pneumonitis ⁷⁴

Pneumonia Aspiration ⁵⁶

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Diseases of the respiratory system

Lung diseases due to external agents

Pneumonitis due to solids and liquids

Pneumonitis due to food and vomit

External Ids:

Disease Ontology ¹² DOID:0050152

MeSH ⁴⁵ D011015

SNOMED-CT ⁶⁹ 47839005

ICD10 ³⁴ J69.0

EFO ¹⁷ EFO_1001399

UMLS ⁷⁴ C0032290 C1761609

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Summaries for Aspiration Pneumonia

Disease Ontology : ¹² A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to aspiration pneumonitis and megaesophagus. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase). The drugs Fentanyl and Desflurane have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotypes are homeostasis/metabolism and renal/urinary system

Wikipedia : ⁷⁷ Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

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Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 181)

#	Related Disease	Score	Top Affiliating Genes
1	aspiration pneumonitis	32.8	ATP12A ATP4A
2	megaesophagus	11.5
3	oculopharyngeal muscular dystrophy	11.2
4	orofaciodigital syndrome ix	11.2
5	spastic paraplegia 2, x-linked	11.2
6	spinal and bulbar muscular atrophy, x-linked 1	11.2
7	eclampsia	11.2
8	anaerobic pneumonia	11.2
9	corticobasal degeneration	11.2
10	fukuyama type muscular dystrophy	11.2
11	microgastria limb reduction defect	11.2
12	x-linked dystonia-parkinsonism/lubag	11.2
13	pneumonia	11.1
14	dysphagia	10.4
15	leukocyte adhesion deficiency, type i	10.3	IL17A ITGAM
16	chronic inflammatory demyelinating polyradiculoneuropathy	10.3	ALB IL17A
17	polyradiculoneuropathy	10.3	ALB IL17A
18	autoimmune optic neuritis	10.2	IL17A ITGAM
19	fungal esophagitis	10.2	ATP12A ATP4A
20	diclofenac allergy	10.2	ATP12A ATP4A
21	gastroduodenal crohn's disease	10.2	ATP12A ATP4A
22	neonatal candidiasis	10.2	ATP12A ATP4A
23	photoallergic dermatitis	10.2	ATP12A ATP4A
24	squamous papillomatosis	10.2	ATP12A ATP4A
25	toxic megacolon	10.2	ATP12A ATP4A
26	gastrointestinal neuroendocrine benign tumor	10.2	ATP12A ATP4A
27	gastric antral vascular ectasia	10.2	ATP12A ATP4A
28	granulomatous gastritis	10.2	ATP12A ATP4A
29	esophageal candidiasis	10.2	ATP12A ATP4A
30	gastric neuroendocrine neoplasm	10.2	ATP12A ATP4A
31	acute laryngitis	10.2	ATP12A ATP4A
32	laryngitis	10.2	ATP12A ATP4A
33	duodenitis	10.2	ATP12A ATP4A
34	rumination disorder	10.2	ATP12A ATP4A
35	active peptic ulcer disease	10.2	ATP12A ATP4A
36	congenital disorder of deglycosylation	10.2	ATP12A ATP4A
37	bladder calculus	10.2	ATP12A ATP4A
38	ischemic neuropathy	10.2	ATP12A ATP4A
39	bile reflux	10.2	ATP12A ATP4A
40	peptic esophagitis	10.2	ATP12A ATP4A
41	hernia, hiatus	10.2	ATP12A ATP4A
42	postsurgical hypothyroidism	10.2	ATP12A ATP4A
43	lymphocytic colitis	10.2	ATP12A ATP4A
44	clostridium difficile colitis	10.2	ATP12A ATP4A
45	diarrhea 1, secretory chloride, congenital	10.2	ATP12A ATP4A
46	esophagitis, eosinophilic, 1	10.2	ATP12A ATP4A
47	microscopic colitis	10.2	ATP12A ATP4A
48	laryngeal tuberculosis	10.2	ATP12A ATP4A
49	chronic laryngitis	10.2	ATP12A ATP4A
50	eosinophilic gastritis	10.2	ATP12A ATP4A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:

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Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.61	ALB ATP12A ATP4A CHAT CHST8 IL17A
2	renal/urinary system	MP:0005367	9.02	ALB ATP12A IL17A TAC1 TRPV1

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Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 195)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Fentanyl

Approved, Illicit, Investigational, Vet_approved

Phase 4,Not Applicable

437-38-7

3345

Desflurane

Approved

Phase 4

57041-67-5

42113

Propofol

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

2078-54-8

4943

Remifentanil

Approved

Phase 4,Not Applicable

132875-61-7

60815

Chlorhexidine

Approved, Vet_approved

Phase 4,Not Applicable

55-56-1

2713 9552079

Ampicillin

Approved, Vet_approved

Phase 4,Phase 3

69-53-4

6249

Sulbactam

Approved

Phase 4,Phase 3

68373-14-8

tannic acid

Approved

Phase 4,Not Applicable

1401-55-4

Atracurium

Approved, Experimental, Investigational

Phase 4

64228-79-1

47319

Cisatracurium

Approved

Phase 4

96946-41-7

Succinylcholine

Approved

Phase 4

306-40-1

5314

Benzocaine

Approved, Investigational

Phase 4,Not Applicable

1994-09-7, 94-09-7

2337

Neostigmine

Approved, Vet_approved

Phase 4,Not Applicable

59-99-4

4456

Dexmedetomidine

Approved, Vet_approved

Phase 4

113775-47-6

5311068 68602

Lisinopril

Approved, Investigational

Phase 4

83915-83-7, 76547-98-3

5362119

Ramosetron

Investigational

Phase 4

132036-88-5

Chlorine dioxide

Investigational

Phase 4

10049-04-4

Anesthetics

Phase 4,Phase 3,Not Applicable

Anti-Infective Agents

Phase 4,Phase 2,Phase 3,Not Applicable

Bronchodilator Agents

Phase 4,Phase 3,Phase 1,Not Applicable

Antibiotics, Antitubercular

Phase 4,Phase 2,Phase 3,Not Applicable

Anti-Bacterial Agents

Phase 4,Phase 2,Phase 3,Not Applicable

Neurotransmitter Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1

Autonomic Agents

Phase 4,Phase 3,Phase 1,Not Applicable

Protective Agents

Phase 4,Phase 3,Phase 1

Hypnotics and Sedatives

Phase 4,Phase 3

Central Nervous System Depressants

Phase 4,Phase 3,Not Applicable

Antiemetics

Phase 4,Not Applicable

Anesthetics, General

Phase 4,Phase 3

Anesthetics, Intravenous

Phase 4,Phase 3

Anti-Infective Agents, Local

Phase 4,Not Applicable

Chlorhexidine gluconate

Phase 4,Not Applicable

Dermatologic Agents

Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable

Disinfectants

Phase 4,Not Applicable

Cholinergic Antagonists

Phase 4

Neuromuscular Nondepolarizing Agents

Phase 4

Neuromuscular Depolarizing Agents

Phase 4

Neuromuscular Agents

Phase 4,Phase 3,Phase 1,Phase 2

Neuromuscular Blocking Agents

Phase 4,Not Applicable

Cholinergic Agents

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Adrenergic Agonists

Phase 4,Not Applicable

Adrenergic alpha-Agonists

Phase 4,Not Applicable

Adrenergic Agents

Phase 4,Not Applicable

Cholinesterase Inhibitors

Phase 4,Not Applicable

HIV Protease Inhibitors

Phase 4,Not Applicable

protease inhibitors

Phase 4,Not Applicable

Analgesics, Non-Narcotic

Phase 4

Analgesics

Phase 4

Adrenergic alpha-2 Receptor Agonists

Phase 4

Interventional clinical trials:

(show top 50) (show all 148)

#	Name	Status	NCT ID	Phase	Drugs
1	The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy	Completed	NCT01402622	Phase 4	Propofol anesthesia
2	Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management	Completed	NCT01710891	Phase 4
3	Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients	Completed	NCT00610324	Phase 4	Chlorhexidine gluconate;Potassium permanganate
4	Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications	Completed	NCT02644876	Phase 4	Penehyclidine inhalation;Placebo inhalation
5	Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques	Completed	NCT01463540	Phase 4
6	Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders	Completed	NCT03533335	Phase 4
7	Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery	Completed	NCT02635542	Phase 4	Succinylcholine;Cisatracurium
8	PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration	Recruiting	NCT02862314	Phase 4
9	Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation	Recruiting	NCT02958150	Phase 4	Dexmedetomidine
10	The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications	Active, not recruiting	NCT02861131	Phase 4	Sugammadex;Neostigmine
11	Avoiding Neuromuscular Blockers to Reduce Complications	Not yet recruiting	NCT03962725	Phase 4	Neuromuscular Blocking Agents;Anesthetic Adjuncts
12	Drug to Prevent Pneumonia in the Tube Fed	Terminated	NCT02358642	Phase 4	Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
13	IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis	Terminated	NCT00774631	Phase 4
14	Pre Hospital Evaluation of Video Laryngoscopy	Withdrawn	NCT01374061	Phase 4
15	Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia	Unknown status	NCT01598402	Phase 2, Phase 3	amoxicillin/clavulanic acid suspension
16	SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition	Unknown status	NCT02175979	Phase 3
17	BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia	Completed	NCT01045902	Phase 3	Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
18	Sellick Interest in Rapid Sequence Induction	Completed	NCT02080754	Phase 3
19	Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults	Completed	NCT02610868	Phase 3	MYOBLOC
20	Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in Japan	Recruiting	NCT03336645	Phase 3	SHP615
21	Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting	Recruiting	NCT03336450	Phase 3	SHP615;MHOS/SHP615
22	Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia	Terminated	NCT01971320	Phase 3
23	Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects	Terminated	NCT00000362	Phase 3
24	A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor	Terminated	NCT02377466	Phase 3	Retosiban IV infusion;Placebo IV infusion
25	A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour	Terminated	NCT02292771	Phase 3	Retosiban;Atosiban;Placebo matching retosiban;Placebo matching atosiban
26	Inhaled Nitric Oxide Study for Respiratory Failure in Newborns	Terminated	NCT00005776	Phase 3	Inhaled nitric oxide;Placebo
27	Early Inhaled Nitric Oxide for Respiratory Failure in Newborns	Terminated	NCT00005773	Phase 3	Inhaled Nitric Oxide;Standard iNO therapy
28	Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy	Unknown status	NCT01607307	Phase 2	Oral/enteral TJ-100 solution;Oral/enteral placebo solution
29	Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea	Unknown status	NCT01812993	Phase 2
30	Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia	Completed	NCT01777672	Phase 2
31	Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging	Completed	NCT03050957	Phase 2
32	Cough and Swallow Rehab Following Stroke	Completed	NCT01907321	Phase 1, Phase 2	Measures performed on all subjects
33	Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts	Completed	NCT00773227	Phase 2
34	Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease	Completed	NCT01479127	Phase 2	ABT-SLV187;Oral Levodopa/Carbidopa
35	Dysport for the Treatment of OMD	Completed	NCT01921270	Phase 1, Phase 2	Low Dose - AbobotulinumtoxinA
36	Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial	Recruiting	NCT02927691	Phase 2
37	Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer	Recruiting	NCT03224000	Phase 2
38	Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation	Active, not recruiting	NCT01758991	Phase 1, Phase 2
39	Proof of Concept (POC) in Patients With Ischaemic Stroke	Terminated	NCT01808261	Phase 2	GSK249320 100/mg;Placebo
40	GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals	Unknown status	NCT02584751	Phase 1	Omeprazole
41	Cough According to Stimulus Type in PD	Completed	NCT02390089	Phase 1	Capsaicin vapor
42	Fecal Microbiota Transplantation for Treatment of Refractory Graft Versus Host Disease-a Pilot Study	Not yet recruiting	NCT03549676	Phase 1
43	Dynamic Laryngotracheal Separation for Aspiration	Suspended	NCT00580346	Phase 1
44	Validation of Aspiration Markers	Withdrawn	NCT02301845	Phase 1	Diatoms Shells
45	Bronchial Alpha Amylase as a Marker for Early Aspiration Pneumonia in Therapeutic Hypothermia.	Unknown status	NCT03007862
46	Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation	Unknown status	NCT03108430
47	Pre-Procedural Fasting in Cardiac Intervention	Unknown status	NCT02562638	Not Applicable
48	Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment	Unknown status	NCT02243722
49	Laparoscopy Heller Myotomy With Fundoplication Associated Versus Peroral Endoscopic Myotomy (POEM)	Unknown status	NCT02138643	Not Applicable
50	Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy	Unknown status	NCT02983175	Not Applicable

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

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Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

#	Genetic test	Affiliating Genes
1	Aspiration Pneumonia ³⁰

Sources

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

⁴²

Lung, Colon, Testes, Liver, Cortex, Brain, Neutrophil

Sources

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 576)

#	Title	Authors	Year
1	The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit. ( 29603057 )	Perry SE...Huckabee ML	2019
2	Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature: Reply. ( 30119837 )	Gurrera RJ...Perry NL	2019
3	Dysphagia and aspiration pneumonia in elderly hospitalization stroke patients: Risk factors, cerebral infarction area comparison. ( 30223382 )	Xu Z...Zhang J	2019
4	Diagnostic Accuracy of Procalcitonin for Early Aspiration Pneumonia in Critically Ill Patients with Coma: A Prospective Study. ( 30267280 )	Legriel S...PCT INHAL study group	2019
5	Effects of preoperative cisapride on postoperative aspiration pneumonia in dogs with laryngeal paralysis. ( 30387153 )	Ogden J...Saile K	2019
6	Aspiration pneumonia and pneumonitis: a spectrum of infectious/noninfectious diseases affecting the lung. ( 30676341 )	Neill S...Dean N	2019
7	Aspiration Pneumonia. ( 30763196 )	Mandell LA...Niederman MS	2019
8	Aspiration Pneumonia in Older Adults. ( 30794136 )	Makhnevich A...Sinvani L	2019
9	Clinical and radiographic findings in cats with aspiration pneumonia: retrospective evaluation of 28 cases. ( 30843218 )	Levy N...Koenigshof A	2019
10	Meconium aspiration pneumonia and otitis media in two goat kids. ( 30852957 )	Newman SJ...Fasina OO	2019
11	The Mortality and the Risk of Aspiration Pneumonia Related with Dysphagia in Stroke Patients. ( 30857927 )	Feng MC...Hung CH	2019
12	Antimicrobial susceptibilities of clinical isolates of the anaerobic bacteria which can cause aspiration pneumonia. ( 30951830 )	Fujita K...Mikamo H	2019
13	Proportion of Aspiration Pneumonia Cases Among Patients With Community-Acquired Pneumonia: A Single-Center Study in Korea. ( 31072078 )	Jeon I...Oh BM	2019
14	Long-Term Mortality and Prognostic Factors in Aspiration Pneumonia. ( 31080159 )	Yoon HY...Ryu YJ	2019
15	Could Polymerase Chain Reaction-Based Methods Differentiate Pneumonitis From Bacterial Aspiration Pneumonia? ( 29252957 )	Tortuyaux R...Nseir S	2018
16	Variation in the Diagnosis of Aspiration Pneumonia and Association with Hospital Pneumonia Outcomes. ( 29298090 )	Lindenauer PK...Dorsey K	2018
17	Relationship of aspiration pneumonia to cognitive impairment and oral condition: a cross-sectional study. ( 29388021 )	Naruishi K...Nagata T	2018
18	Silent aspiration predicts mortality in older adults with aspiration pneumonia admitted to acute hospitals. ( 29388314 )	Nakashima T...Akagi J	2018
19	A Randomized Controlled Trial to Investigate the Effectiveness of the Prevention of Aspiration Pneumonia Using Recommendations for Swallowing Care Guided by Ultrasound Examination. ( 29439537 )	Miura Y...Sanada H	2018
20	Using oral health assessment to predict aspiration pneumonia in older adults. ( 29446124 )	Noguchi S...Mukae H	2018
21	Project SITUP: An Interdisciplinary Quality Improvement Initiative to Reduce Aspiration Pneumonia. ( 29466260 )	O?Malley MB...Bradway C	2018
22	ASPIRATION PNEUMONIA IN TWO TIBETAN YAK BULLS ( BOS GRUNNIENS) AS A COMPLICATION OF KETAMINE-XYLAZINE-BUTORPHANOL ANESTHESIA FOR RECUMBENT CASTRATION. ( 29517446 )	Smith JS...Chigerwe M	2018
23	The importance of oral health to prevent aspiration pneumonia. ( 29531209 )	Normaliza AM...Colman MG	2018
24	Aspiration Pneumonia as a Cause of Death in Critically Ill Patients with Dysphagia After Extubation. ( 29538126 )	Taito S...Ishida S	2018
25	Bacteriological testing and recurrence prevention efforts in the diagnosis and treatment of nursing- and healthcare-associated pneumonia and aspiration pneumonia: A questionnaire survey of hospitals across Japan. ( 29548653 )	Kenzaka T...Yahata S	2018
26	Pre-stroke undiagnosed dysphagia lusoria as a rare cause of aspiration pneumonia with respiratory failure in a stroke patient. ( 29552342 )	Spatenkova V...Jedlicka J	2018
27	Comparison of Videofluoroscopic Swallowing Study and Radionuclide Salivagram for Aspiration Pneumonia in Children With Swallowing Difficulty. ( 29560324 )	Kim GE...Kim JS	2018
28	Aspiration Pneumonia and Related Syndromes. ( 29730088 )	Lee AS...Ryu JH	2018
29	Erratum to "The possible protective role of pumpkin seed oil in an animal model of acid aspiration pneumonia: Light and electron microscopic study Acta Histochemica 119 (2017) 161-171". ( 29764621 )	Omar NM...Sarhan NR	2018
30	Effect of starting oral intake on weekends on the clinical course of patients with aspiration pneumonia. ( 29780243 )	Kenzaka T...Okayama M	2018
31	Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems. ( 29790300 )	Komatsu R...Ichinose M	2018
32	Assessment of aspiration pneumonia using the Anticholinergic Risk Scale. ( 29856113 )	Kose E...Seki T	2018
33	Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease. ( 29874285 )	Tomita S...Sawada H	2018
34	Repetitive Aspiration Pneumonia Caused by Basilar Impression. ( 29877294 )	Kawabata H...Yatera K	2018
35	Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study. ( 29932081 )	Papadopoulos D...Filaditaki V	2018
36	Determining Peak Cough Flow Cutoff Values to Predict Aspiration Pneumonia Among Patients With Dysphagia Using the Citric Acid Reflexive Cough Test. ( 29981313 )	Sohn D...Im S	2018
37	Incidence of aspiration pneumonia during hospitalization in Japanese hospitalized cases did not increase whereas concern factors were exacerbated in a time-dependent manner: analysis of Diagnosis Procedure Combination (DPC) data. ( 30087546 )	Nonaka S...Fujimoto K	2018
38	Asymptomatic dysphagia causing recurrent aspiration pneumonia. ( 30131410 )	L?kke A...Hilberg O	2018
39	Predictors for achieving oral intake in older patients with aspiration pneumonia: Videofluoroscopic evaluation of swallowing function. ( 30168244 )	Ito M...Liu M	2018
40	Retrospective analysis of incidence, clinical features, potential risk factors, and prognostic indicators for aspiration pneumonia in three brachycephalic dog breeds. ( 30211637 )	Darcy HP...Ter Haar G	2018
41	A novel semi-solidifying liquid formula via the nasogastric route to maintain enteral nutrition in the event of recurrent aspiration pneumonia: A case report. ( 30214747 )	Toh Yoon EW	2018
42	Use of prophylactic antibiotics in aspiration pneumonia. ( 30321306 )	Karabay O...Karabay M	2018
43	Antibacterial treatment of aspiration pneumonia in older people: a systematic review. ( 30464429 )	Bowerman TJ...Waite LM	2018
44	Clinical significance and efficacy analysis of atorvastatin in the treatment of patients with cerebral infarction and aspiration pneumonia. ( 30542469 )	Wei B...Liu Y	2018
45	Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis. ( 30556343 )	Byun SE...Sim Y	2018
46	Observations from a pediatric dysphagia clinic: Characteristics of children at risk of aspiration pneumonia. ( 30582163 )	Pavithran J...Iyer S	2018
47	Different clinical predictors of aspiration pneumonia in dysphagic stroke patients related to stroke lesion: A STROBE-complaint retrospective study. ( 30593222 )	Yu KJ...Park D	2018
48	The impact of aspiration pneumonia and nasogastric feeding on clinical outcomes in stroke patients: A retrospective cohort study. ( 28618137 )	Schwarz M...Cardell E	2018
49	Diagnostic performance of initial serum albumin level for predicting in-hospital mortality among aspiration pneumonia patients. ( 28666627 )	Kim H...Park B	2018
50	The occurrence of aspiration pneumonia after emergency endotracheal intubation. ( 28760377 )	Driver BE...Miner JR	2018

Sources

Genes for Aspiration Pneumonia

Genes related to Aspiration Pneumonia (1 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CHAT	Choline O-Acetyltransferase	Protein Coding	417.96	Pathogenic ⁶ GeneCards inferred via : Variants (show sections)
2	MYH2	Myosin Heavy Chain 2	Protein Coding	20.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	IL17A	Interleukin 17A	Protein Coding	20.09	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	ITGAM	Integrin Subunit Alpha M	Protein Coding	16.66	GeneCards inferred via : Publications (show sections)
5	TEF	TEF Transcription Factor, PAR BZIP Family Member	Protein Coding	16.66	DISEASES inferred ¹⁵
6	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	15.62	DISEASES inferred ¹⁵
7	ALB	Albumin	Protein Coding	15.57	DISEASES inferred ¹⁵
8	TAC1	Tachykinin Precursor 1	Protein Coding	15.56	DISEASES inferred ¹⁵
9	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	15.55	DISEASES inferred ¹⁵
10	CHST8	Carbohydrate Sulfotransferase 8	Protein Coding	15.51	DISEASES inferred ¹⁵
11	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	15	DISEASES inferred ¹⁵
12	FLAD1	Flavin Adenine Dinucleotide Synthetase 1	Protein Coding	14.81	DISEASES inferred ¹⁵

Sources

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

⁶

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	CHAT	NM_020549.4(CHAT): c.1061C> T (p.Thr354Met)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs769234940	GRCh37	Chromosome 10, 50835781: 50835781
2	CHAT	NM_020549.4(CHAT): c.1061C> T (p.Thr354Met)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs769234940	GRCh38	Chromosome 10, 49627735: 49627735
3	CHAT	NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys)	single nucleotide variant	Pathogenic	rs201439531	GRCh37	Chromosome 10, 50872926: 50872926
4	CHAT	NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys)	single nucleotide variant	Pathogenic	rs201439531	GRCh38	Chromosome 10, 49664880: 49664880

Sources

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Sources

Pathways for Aspiration Pneumonia

Sources

GO Terms for Aspiration Pneumonia

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	potassium ion import across plasma membrane	GO:1990573	9.46	ATP12A ATP4A
2	cellular response to nerve growth factor stimulus	GO:1990090	9.43	TAC1 TRPV1
3	ATP hydrolysis coupled proton transport	GO:0015991	9.4	ATP12A ATP4A
4	response to pain	GO:0048265	9.37	TAC1 TRPV1
5	microglial cell activation	GO:0001774	9.32	ITGAM TRPV1
6	cellular sodium ion homeostasis	GO:0006883	9.26	ATP12A ATP4A
7	establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	9.16	ATP12A ATP4A
8	cellular potassium ion homeostasis	GO:0030007	8.96	ATP12A ATP4A
9	sodium ion export across plasma membrane	GO:0036376	8.62	ATP12A ATP4A

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sodium:potassium-exchanging ATPase activity	GO:0005391	8.96	ATP12A ATP4A
2	potassium:proton exchanging ATPase activity	GO:0008900	8.62	ATP12A ATP4A

Sources

Sources for Aspiration Pneumonia

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

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⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

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¹⁴ DiseaseEnhancer

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¹⁶ DrugBank

¹⁷ EFO

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¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia