Aspiration Pneumonia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ASP007 MIFTS: 46	Aspiration Pneumonia Categories: Gastrointestinal diseases, Respiratory diseases
Genes Variations Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia ¹² ⁷⁶ ²⁹ ⁶ ¹⁵ ⁷³

Aspiration Pneumonitis ⁷³

Pneumonia, Aspiration ⁴⁴

Pneumonia Aspiration ⁵⁵

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the respiratory system

Lung diseases due to external agents

Pneumonitis due to solids and liquids

Pneumonitis due to food and vomit

External Ids:

Disease Ontology ¹² DOID:0050152

ICD10 ³³ J69.0

MeSH ⁴⁴ D011015

SNOMED-CT ⁶⁸ 47839005

UMLS ⁷³ C0032290 C1761609

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Summaries for Aspiration Pneumonia

Disease Ontology : ¹² A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as aspiration pneumonitis, is related to aspiration pneumonitis and megaesophagus. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways is Ion channel transport. The drugs Propofol and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and testes, and related phenotype is homeostasis/metabolism.

Wikipedia : ⁷⁶ Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

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Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)

#	Related Disease	Score	Top Affiliating Genes
1	aspiration pneumonitis	32.4	ATP12A ATP4A
2	megaesophagus	11.5
3	oculopharyngeal muscular dystrophy	11.1
4	orofaciodigital syndrome ix	11.1
5	spastic paraplegia 2, x-linked	11.1
6	spinal and bulbar muscular atrophy, x-linked 1	11.1
7	eclampsia	11.1
8	anaerobic pneumonia	11.1
9	corticobasal degeneration	11.1
10	fukuyama type muscular dystrophy	11.1
11	microgastria limb reduction defect	11.1
12	x-linked dystonia-parkinsonism/lubag	11.1
13	pneumonia	11.0
14	dysphagia	10.4
15	leiomyoma cutis	10.2	TAC1 TRPV1
16	leukocyte adhesion deficiency, type i	10.2	IL17A ITGAM
17	autoimmune optic neuritis	10.2	IL17A ITGAM
18	trigeminal nerve disease	10.1	TAC1 TRPV1
19	burning mouth syndrome	10.1	TAC1 TRPV1
20	mononeuropathy	10.1	TAC1 TRPV1
21	dental pulp disease	10.1	TAC1 TRPV1
22	chronic inflammatory demyelinating polyradiculoneuropathy	10.1	ALB IL17A
23	polyradiculoneuropathy	10.1	ALB IL17A
24	central nervous system disease	10.1	CHAT IL17A TRPV1
25	cardiovascular organ benign neoplasm	10.1	TAC1 TRPV1
26	benign perivascular tumor	10.1	TAC1 TRPV1
27	bronchial disease	10.1	IL17A TAC1 TRPV1
28	pain agnosia	10.1	TAC1 TRPV1
29	autonomic nervous system disease	10.1	ALB TAC1
30	agnosia	10.0	TAC1 TRPV1
31	nervous system disease	10.0	ALB CHAT TRPV1
32	lung abscess	10.0
33	immune system disease	10.0	ALB IL17A TRPV1
34	intestinal disease	10.0	ALB IL17A TRPV1
35	respiratory system disease	10.0	ALB IL17A TRPV1
36	nasal cavity disease	10.0	TAC1 TRPV1
37	somatoform disorder	10.0	TAC1 TRPV1
38	peripheral nervous system disease	10.0	ALB TAC1 TRPV1
39	stroke, ischemic	10.0
40	cerebrovascular disease	10.0
41	achalasia	10.0
42	nose disease	10.0	TAC1 TRPV1
43	meningoencephalitis	10.0	ALB TAC1
44	drug allergy	9.9	ALB ATP12A
45	fungal esophagitis	9.9	ATP12A ATP4A
46	diclofenac allergy	9.9	ATP12A ATP4A
47	gastroduodenal crohn's disease	9.9	ATP12A ATP4A
48	neonatal candidiasis	9.9	ATP12A ATP4A
49	photoallergic dermatitis	9.9	ATP12A ATP4A
50	squamous papillomatosis	9.9	ATP12A ATP4A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:

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Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.28	ALB ATP12A ATP4A CHAT CHST8 IL17A

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Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 190)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Propofol

Approved, Investigational, Vet_approved

Phase 4

2078-54-8

4943

Fentanyl

Approved, Illicit, Investigational, Vet_approved

Phase 4,Not Applicable

437-38-7

3345

Desflurane

Approved

Phase 4

57041-67-5

42113

Remifentanil

Approved

Phase 4

132875-61-7

60815

Chlorhexidine

Approved, Vet_approved

Phase 4,Not Applicable

55-56-1

2713 9552079

Sulbactam

Approved

Phase 4,Phase 3

68373-14-8

Ampicillin

Approved, Vet_approved

Phase 4,Phase 3

69-53-4

6249

Neostigmine

Approved, Vet_approved

Phase 4,Not Applicable

59-99-4

4456

Salmon Calcitonin

Approved, Investigational

Phase 4

47931-85-1

16129616

Dexmedetomidine

Approved, Vet_approved

Phase 4

113775-47-6

68602 5311068

Lisinopril

Approved, Investigational

Phase 4

83915-83-7, 76547-98-3

5362119

Ramosetron

Investigational

Phase 4

132036-88-5

Chlorine dioxide

Investigational

Phase 4

10049-04-4

Calcitonin gene-related peptide

Investigational

Phase 4

83652-28-2

Central Nervous System Depressants

Phase 4,Phase 3,Not Applicable

Anesthetics

Phase 4,Phase 3,Not Applicable

Anesthetics, General

Phase 4,Phase 3

Anti-Infective Agents

Phase 4,Phase 2,Phase 3,Not Applicable

Anti-Infective Agents, Local

Phase 4,Not Applicable

Anti-Bacterial Agents

Phase 4,Phase 2,Phase 3,Not Applicable

Antibiotics, Antitubercular

Phase 4,Phase 2,Phase 3

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1

Neurotransmitter Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Bronchodilator Agents

Phase 4,Phase 1,Not Applicable

Autonomic Agents

Phase 4,Phase 1,Not Applicable

Protective Agents

Phase 4,Phase 1

Hypnotics and Sedatives

Phase 4,Phase 3

Antiemetics

Phase 4,Not Applicable

Anesthetics, Intravenous

Phase 4,Phase 3

Dermatologic Agents

Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable

Chlorhexidine gluconate

Phase 4,Not Applicable

Disinfectants

Phase 4,Not Applicable

Adrenergic Agonists

Phase 4,Not Applicable

Adrenergic alpha-Agonists

Phase 4,Not Applicable

Adrenergic Agents

Phase 4,Not Applicable

Cholinergic Agents

Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Cholinesterase Inhibitors

Phase 4,Not Applicable

HIV Protease Inhibitors

Phase 4,Not Applicable

protease inhibitors

Phase 4,Not Applicable

Neuromuscular Blocking Agents

Phase 4,Not Applicable

Bone Density Conservation Agents

Phase 4

calcitonin

Phase 4

Analgesics

Phase 4

Analgesics, Non-Narcotic

Phase 4

Adrenergic alpha-2 Receptor Agonists

Phase 4

Adjuvants, Anesthesia

Phase 4,Phase 3

Cholinergic Antagonists

Phase 4

Muscarinic Antagonists

Phase 4

Glycopyrrolate

Phase 4

596-51-0

3494

Antihypertensive Agents

Phase 4

Interventional clinical trials:

(show top 50) (show all 134)

#	Name	Status	NCT ID	Phase	Drugs
1	The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy	Completed	NCT01402622	Phase 4	Propofol anesthesia
2	Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients	Completed	NCT00610324	Phase 4	Chlorhexidine gluconate;Potassium permanganate
3	Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management	Completed	NCT01710891	Phase 4
4	Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques	Completed	NCT01463540	Phase 4
5	Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders	Completed	NCT03533335	Phase 4
6	PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration	Recruiting	NCT02862314	Phase 4
7	Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation	Recruiting	NCT02958150	Phase 4	Dexmedetomidine
8	Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications	Active, not recruiting	NCT02644876	Phase 4	Penehyclidine inhalation;Placebo inhalation
9	The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications	Active, not recruiting	NCT02861131	Phase 4	Sugammadex;Neostigmine
10	Drug to Prevent Pneumonia in the Tube Fed	Terminated	NCT02358642	Phase 4	Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
11	IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis	Terminated	NCT00774631	Phase 4
12	Pre Hospital Evaluation of Video Laryngoscopy	Withdrawn	NCT01374061	Phase 4
13	Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Head and Neck Cancer to Prevent Aspiration Pneumonia	Unknown status	NCT01598402	Phase 2, Phase 3	amoxicillin/clavulanic acid suspension
14	BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia	Completed	NCT01045902	Phase 3	Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
15	Sellick Interest in Rapid Sequence Induction	Completed	NCT02080754	Phase 3
16	Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults	Completed	NCT02610868	Phase 3	MYOBLOC
17	Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in Japan	Recruiting	NCT03336645	Phase 3	SHP615
18	Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting	Recruiting	NCT03336450	Phase 3	SHP615;MHOS/SHP615
19	SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition	Active, not recruiting	NCT02175979	Phase 3
20	Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia	Terminated	NCT01971320	Phase 3
21	Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects	Terminated	NCT00000362	Phase 3
22	A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor	Terminated	NCT02377466	Phase 3	Retosiban IV infusion;Placebo IV infusion
23	A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour	Terminated	NCT02292771	Phase 3	Retosiban;Atosiban;Placebo matching retosiban;Placebo matching atosiban
24	Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy	Unknown status	NCT01607307	Phase 2	Oral/enteral TJ-100 solution;Oral/enteral placebo solution
25	Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea	Unknown status	NCT01812993	Phase 2
26	Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia	Completed	NCT01777672	Phase 2
27	Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging	Completed	NCT03050957	Phase 2
28	Cough and Swallow Rehab Following Stroke	Completed	NCT01907321	Phase 1, Phase 2	Measures performed on all subjects
29	Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts	Completed	NCT00773227	Phase 2
30	Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease	Completed	NCT01479127	Phase 2	ABT-SLV187;Oral Levodopa/Carbidopa
31	Dysport for the Treatment of OMD	Completed	NCT01921270	Phase 1, Phase 2	Low Dose - AbobotulinumtoxinA
32	Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial	Recruiting	NCT02927691	Phase 2
33	Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer	Recruiting	NCT03224000	Phase 2
34	Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation	Active, not recruiting	NCT01758991	Phase 1, Phase 2
35	Proof of Concept (POC) in Patients With Ischaemic Stroke	Terminated	NCT01808261	Phase 2	GSK249320 100/mg;Placebo
36	GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals	Unknown status	NCT02584751	Phase 1	Omeprazole
37	Cough According to Stimulus Type in PD	Active, not recruiting	NCT02390089	Phase 1	Capsaicin vapor
38	Fecal Microbiota Transplantation for Treatment of Refractory Graft Versus Host Disease-a Pilot Study	Not yet recruiting	NCT03549676	Phase 1
39	Dynamic Laryngotracheal Separation for Aspiration	Suspended	NCT00580346	Phase 1
40	Pre-Procedural Fasting in Cardiac Intervention	Unknown status	NCT02562638	Not Applicable
41	Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment	Unknown status	NCT02243722
42	Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy	Unknown status	NCT02983175	Not Applicable
43	Comparison of Ultrasound and Videofluoroscopic Imaging Techniques in Diagnosing Dysphagia in Stroke Patients	Unknown status	NCT01249300
44	Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy	Unknown status	NCT00536952	Early Phase 1	Pulmozyme;Placebo
45	EtCO2 Monitoring in Acute Self-poisoning	Unknown status	NCT01800123
46	Mechanical Ventilation During Cardiac Surgery	Unknown status	NCT02090205	Not Applicable
47	Minimal-Massive Intervention in Elderly Patients With Dysphagia	Unknown status	NCT02396992	Not Applicable
48	General Anesthesia for Endovascular Thrombectomy; A Pilot Study.	Unknown status	NCT02639806		Sevoflurane;Lidocaine
49	The Research of the Evaluation of Clinical Procedures in Gastroesophageal Varices in Patients With Liver Cirrhosis	Unknown status	NCT01592578	Not Applicable
50	The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on the Incidence of Aspiration Pneumonia and Postoperative Length of Stay	Completed	NCT02858596	Not Applicable

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

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Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

#	Genetic test	Affiliating Genes
1	Aspiration Pneumonia ²⁹

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Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

⁴¹

Lung, Colon, Testes, Brain, Tongue, Liver, Cortex

Sources

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 571)

#	Title	Authors	Year
1	Effect of starting oral intake on weekends on the clinical course of patients with aspiration pneumonia. ( 29780243 )	Kenzaka T....Okayama M.	2018
2	A Randomized Controlled Trial to Investigate the Effectiveness of the Prevention of Aspiration Pneumonia Using Recommendations for Swallowing Care Guided by Ultrasound Examination. ( 29439537 )	Miura Y....Sanada H.	2018
3	Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems. ( 29790300 )	Komatsu R....Ichinose M.	2018
4	Using oral health assessment to predict aspiration pneumonia in older adults. ( 29446124 )	Noguchi S....Mukae H.	2018
5	Comparison of Videofluoroscopic Swallowing Study and Radionuclide Salivagram for Aspiration Pneumonia in Children With Swallowing Difficulty. ( 29560324 )	Kim G.E....Kim J.S.	2018
6	Pre-stroke undiagnosed dysphagia lusoria as a rare cause of aspiration pneumonia with respiratory failure in a stroke patient. ( 29552342 )	Spatenkova V....Jedlicka J.	2018
7	Bacteriological testing and recurrence prevention efforts in the diagnosis and treatment of nursing- and healthcare-associated pneumonia and aspiration pneumonia: A questionnaire survey of hospitals across Japan. ( 29548653 )	Kenzaka T....Yahata S.	2018
8	Aspiration Pneumonia as a Cause of Death in Critically Ill Patients with Dysphagia After Extubation. ( 29538126 )	Taito S....Ishida S.	2018
9	Variation in the Diagnosis of Aspiration Pneumonia and Association with Hospital Pneumonia Outcomes. ( 29298090 )	Lindenauer P.K....Dorsey K.	2018
10	Silent aspiration predicts mortality in older adults with aspiration pneumonia admitted to acute hospitals. ( 29388314 )	Nakashima T....Akagi J.	2018
11	Could Polymerase Chain Reaction-Based Methods Differentiate Pneumonitis From Bacterial Aspiration Pneumonia? ( 29252957 )	Tortuyaux R....Nseir S.	2018
12	Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease. ( 29874285 )	Tomita S....Sawada H.	2018
13	Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study. ( 29932081 )	Papadopoulos D....Filaditaki V.	2018
14	Relationship of aspiration pneumonia to cognitive impairment and oral condition: a cross-sectional study. ( 29388021 )	Naruishi K....Nagata T.	2018
15	Determining peak cough flow cut-off values to predict aspiration pneumonia among patients with dysphagia using the citric acid reflexive cough test. ( 29981313 )	Sohn D....Im S.	2018
16	The importance of oral health to prevent aspiration pneumonia. ( 29531209 )		2018
17	Repetitive Aspiration Pneumonia Caused by Basilar Impression. ( 29877294 )		2018
18	Assessment of aspiration pneumonia using the Anticholinergic Risk Scale. ( 29856113 )		2018
19	Aspiration Pneumonia and Related Syndromes. ( 29730088 )		2018
20	The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit. ( 29603057 )		2018
21	Project SITUP: An Interdisciplinary Quality Improvement Initiative to Reduce Aspiration Pneumonia. ( 29466260 )		2018
22	ASPIRATION PNEUMONIA IN TWO TIBETAN YAK BULLS ( BOS GRUNNIENS) AS A COMPLICATION OF KETAMINE-XYLAZINE-BUTORPHANOL ANESTHESIA FOR RECUMBENT CASTRATION. ( 29517446 )		2018
23	Antibacterial treatment of aspiration pneumonia in older people: a systematic review. ( 30464429 )	Bowerman TJ...Waite LM	2018
24	Clinical significance and efficacy analysis of atorvastatin in the treatment of patients with cerebral infarction and aspiration pneumonia. ( 30542469 )	Wei B...Liu Y	2018
25	Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis. ( 30556343 )	Byun SE...Sim Y	2018
26	The impact of aspiration pneumonia and nasogastric feeding on clinical outcomes in stroke patients: A retrospective cohort study. ( 28618137 )	Schwarz M...Cardell E	2018
27	Erratum to "The possible protective role of pumpkin seed oil in an animal model of acid aspiration pneumonia: Light and electron microscopic study Acta Histochemica 119 (2017) 161-171". ( 29764621 )	Omar NM...Sarhan NR	2018
28	Incidence of aspiration pneumonia during hospitalization in Japanese hospitalized cases did not increase whereas concern factors were exacerbated in a time-dependent manner: analysis of Diagnosis Procedure Combination (DPC) data. ( 30087546 )	Nonaka S...Fujimoto K	2018
29	Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature: Reply. ( 30119837 )	Gurrera RJ...Perry NL	2018
30	Asymptomatic dysphagia causing recurrent aspiration pneumonia. ( 30131410 )	L?kke A...Hilberg O	2018
31	Predictors for achieving oral intake in older patients with aspiration pneumonia: Videofluoroscopic evaluation of swallowing function. ( 30168244 )	Ito M...Liu M	2018
32	Retrospective analysis of incidence, clinical features, potential risk factors, and prognostic indicators for aspiration pneumonia in three brachycephalic dog breeds. ( 30211637 )	Darcy HP...Ter Haar G	2018
33	A novel semi-solidifying liquid formula via the nasogastric route to maintain enteral nutrition in the event of recurrent aspiration pneumonia: A case report. ( 30214747 )	Toh Yoon EW	2018
34	Dysphagia and aspiration pneumonia in elderly hospitalization stroke patients: Risk factors, cerebral infarction area comparison. ( 30223382 )	Xu Z...Zhang J	2018
35	Diagnostic Accuracy of Procalcitonin for Early Aspiration Pneumonia in Critically Ill Patients with Coma: A Prospective Study. ( 30267280 )	Legriel S...PCT INHAL study group	2018
36	Use of prophylactic antibiotics in aspiration pneumonia. ( 30321306 )	Karabay O...Karabay M	2018
37	Effects of preoperative cisapride on postoperative aspiration pneumonia in dogs with laryngeal paralysis. ( 30387153 )	Ogden J...Saile K	2018
38	Diagnostic performance of initial serum albumin level for predicting in-hospital mortality among aspiration pneumonia patients. ( 28666627 )	Kim H....Park B.	2017
39	Effects of aspiration pneumonia on the intensive care requirements and in-hospital mortality of hospitalised patients with acute cerebrovascular disease. ( 28883847 )	GA1ngen A.C....Erkorkmaz A.9.	2017
40	Percutaneous endoscopic gastrostomy for aspiration pneumonia: A 10-year single-center experience. ( 28427747 )	Tomioka H....Kaneko M.	2017
41	Laryngeal tumours and radiotherapy dose to the cricopharyngeus are predictive of death from aspiration pneumonia. ( 28024728 )	O'Hare J....Graham P.	2017
42	Antipsychotics and the Risk of Aspiration Pneumonia in Individuals Hospitalized for Nonpsychiatric Conditions: A Cohort Study. ( 29095482 )	Herzig S.J....Marcantonio E.R.	2017
43	Rehabilitative management for aspiration pneumonia in elderly patients. ( 29263982 )	Momosaki R.	2017
44	Aspiration Pneumonia in Carbon Monoxide Poisoning Patients with Loss of Consciousness: Prevalence, Outcomes, and Risk Factors. ( 28803137 )	Sohn C.H....Kim W.Y.	2017
45	Preoperative Pulmonary Function Tests Predict Aspiration Pneumonia After Gastric Endoscopic Submucosal Dissection. ( 28879570 )	Matsumi A....Kawahara Y.	2017
46	National Trends in Admission for Aspiration Pneumonia in the United States, 2002-2012. ( 28272915 )	Wu C.P....Pinelis E.	2017
47	Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature. ( 28992957 )	Kaplan J....Ward M.C.	2017
48	Ability of High-Resolution Manometry to Determine Feeding Method and to Predict Aspiration Pneumonia in Patients With Dysphagia. ( 28374817 )	Park C.H....Yoon K.J.	2017
49	The occurrence of aspiration pneumonia after emergency endotracheal intubation. ( 28760377 )	Driver B.E....Miner J.R.	2017
50	Efficacy of a New Post-Mouthwash Intervention (Wiping Plus Oral Nutritional Supplements) for Preventing Aspiration Pneumonia in Elderly People: A Multicenter, Randomized, Comparative Trial. ( 29183037 )	Higashiguchi T....Maruyama M.	2017

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Genes for Aspiration Pneumonia

Genes related to Aspiration Pneumonia (1 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CHAT	Choline O-Acetyltransferase	Protein Coding	417.96	Pathogenic ⁶ GeneCards inferred via : Variants (show sections)
2	MYH2	Myosin Heavy Chain 2	Protein Coding	20.63	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	IL17A	Interleukin 17A	Protein Coding	20.16	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	20.14	DISEASES inferred ¹⁵ ¹⁵
5	ITGAM	Integrin Subunit Alpha M	Protein Coding	16.66	GeneCards inferred via : Publications (show sections)
6	TEF	TEF, PAR BZIP Transcription Factor	Protein Coding	16.61	DISEASES inferred ¹⁵
7	CHST8	Carbohydrate Sulfotransferase 8	Protein Coding	15.6	DISEASES inferred ¹⁵
8	TAC1	Tachykinin Precursor 1	Protein Coding	15.59	DISEASES inferred ¹⁵
9	ALB	Albumin	Protein Coding	15.55	DISEASES inferred ¹⁵
10	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	15.52	DISEASES inferred ¹⁵
11	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	15.45	DISEASES inferred ¹⁵
12	GLRA1	Glycine Receptor Alpha 1	Protein Coding	15.02	DISEASES inferred ¹⁵

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Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

⁶

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	CHAT	NM_020549.4(CHAT): c.1061C> T (p.Thr354Met)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs769234940	GRCh37	Chromosome 10, 50835781: 50835781
2	CHAT	NM_020549.4(CHAT): c.1061C> T (p.Thr354Met)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs769234940	GRCh38	Chromosome 10, 49627735: 49627735
3	CHAT	NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys)	single nucleotide variant	Pathogenic	rs201439531	GRCh37	Chromosome 10, 50872926: 50872926
4	CHAT	NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys)	single nucleotide variant	Pathogenic	rs201439531	GRCh38	Chromosome 10, 49664880: 49664880

Sources

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

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Pathways for Aspiration Pneumonia

Pathways related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Ion channel transport ⁶⁶ Show member pathways Stimuli-sensing channels ⁶⁶	11.42	ATP12A ATP4A GLRA1 TRPV1

Sources

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	8.92	GLRA1 IL17A ITGAM TRPV1

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

(show all 11)

#	Name	GO ID	Score	Top Affiliating Genes
1	ion transport	GO:0006811	9.8	ATP12A ATP4A GLRA1 TRPV1
2	potassium ion import across plasma membrane	GO:1990573	9.48	ATP12A ATP4A
3	cellular response to nerve growth factor stimulus	GO:1990090	9.46	TAC1 TRPV1
4	potassium ion import	GO:0010107	9.43	ATP12A ATP4A
5	ATP hydrolysis coupled proton transport	GO:0015991	9.4	ATP12A ATP4A
6	response to pain	GO:0048265	9.37	TAC1 TRPV1
7	microglial cell activation	GO:0001774	9.32	ITGAM TRPV1
8	cellular sodium ion homeostasis	GO:0006883	9.26	ATP12A ATP4A
9	establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	9.16	ATP12A ATP4A
10	cellular potassium ion homeostasis	GO:0030007	8.96	ATP12A ATP4A
11	sodium ion export across plasma membrane	GO:0036376	8.62	ATP12A ATP4A

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sodium:potassium-exchanging ATPase activity	GO:0005391	8.96	ATP12A ATP4A
2	potassium:proton exchanging ATPase activity	GO:0008900	8.62	ATP12A ATP4A

Sources

Sources for Aspiration Pneumonia

¹ BioSystems

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²⁷ GEO DataSets

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³³ ICD10

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⁷⁶ Wikipedia