MCID: ASP007
MIFTS: 46

Aspiration Pneumonia

Categories: Gastrointestinal diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 75 29 6 15 72
Pneumonia, Aspiration 44 17
Aspiration Pneumonitis 72
Pneumonia Aspiration 55

Classifications:



External Ids:

Disease Ontology 12 DOID:0050152
MeSH 44 D011015
SNOMED-CT 68 47839005
ICD10 33 J69.0
UMLS 72 C0032290 C1761609

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to aspiration pneumonitis and peptic esophagitis. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase). The drugs Magnesium citrate and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and colon, and related phenotypes are homeostasis/metabolism and renal/urinary system

Wikipedia : 75 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 292)
# Related Disease Score Top Affiliating Genes
1 aspiration pneumonitis 33.3 ATP4A ATP12A
2 peptic esophagitis 30.3 ATP4A ATP12A
3 hernia, hiatus 30.3 ATP4A ATP12A
4 laryngeal disease 30.0 ATP4A ATP12A
5 microinvasive gastric cancer 29.9 ATP4A ATP12A
6 esophageal disease 28.4 TRPV1 TEF ATP4A ATP12A ALB
7 megaesophagus 11.6
8 oculopharyngeal muscular dystrophy 11.3
9 muscular dystrophy-dystroglycanopathy , type a, 4 11.3
10 orofaciodigital syndrome ix 11.3
11 neurodegeneration with brain iron accumulation 5 11.3
12 spastic paraplegia 2, x-linked 11.3
13 spinal and bulbar muscular atrophy, x-linked 1 11.3
14 dystonia 3, torsion, x-linked 11.3
15 lissencephaly 1 11.3
16 spastic paraplegia 35, autosomal recessive 11.3
17 chops syndrome 11.3
18 eclampsia 11.3
19 anaerobic pneumonia 11.3
20 corticobasal degeneration 11.3
21 fukuyama type muscular dystrophy 11.3
22 microgastria limb reduction defect 11.3
23 x-linked dystonia-parkinsonism/lubag 11.3
24 spastic paraplegia type 49 11.3
25 pneumonia 11.1
26 dysphagia 10.7
27 leukocyte adhesion deficiency, type i 10.4 ITGAM IL17A
28 autoimmune optic neuritis 10.4 ITGAM IL17A
29 fungal esophagitis 10.4 ATP4A ATP12A
30 gastroduodenal crohn's disease 10.4 ATP4A ATP12A
31 diclofenac allergy 10.4 ATP4A ATP12A
32 neonatal candidiasis 10.4 ATP4A ATP12A
33 gastroesophageal reflux 10.4
34 squamous papillomatosis 10.4 ATP4A ATP12A
35 photoallergic dermatitis 10.4 ATP4A ATP12A
36 gastrointestinal neuroendocrine benign tumor 10.4 ATP4A ATP12A
37 toxic megacolon 10.4 ATP4A ATP12A
38 granulomatous gastritis 10.4 ATP4A ATP12A
39 gastric antral vascular ectasia 10.4 ATP4A ATP12A
40 acute laryngitis 10.4 ATP4A ATP12A
41 laryngitis 10.4 ATP4A ATP12A
42 gastric neuroendocrine neoplasm 10.4 ATP4A ATP12A
43 esophageal candidiasis 10.4 ATP4A ATP12A
44 duodenitis 10.3 ATP4A ATP12A
45 active peptic ulcer disease 10.3 ATP4A ATP12A
46 rumination disorder 10.3 ATP4A ATP12A
47 bile reflux 10.3 ATP4A ATP12A
48 ischemic neuropathy 10.3 ATP4A ATP12A
49 bladder calculus 10.3 ATP4A ATP12A
50 congenital disorder of deglycosylation 10.3 ATP4A ATP12A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.65 ALB ATP12A ATP4A CHAT CHST8 IL17A
2 renal/urinary system MP:0005367 9.02 ALB ATP12A IL17A TAC1 TRPV1

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 200)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Magnesium citrate Approved Phase 4 3344-18-1
2
Sodium citrate Approved, Investigational Phase 4 68-04-2
3
Magnesium oxide Approved Phase 4 1309-48-4 14792
4
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
5
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
7
Desflurane Approved Phase 4 57041-67-5 42113
8
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
9
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
10
Remifentanil Approved Phase 4 132875-61-7 60815
11
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
12
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
13
Succinylcholine Approved Phase 4 306-40-1 5314
14
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
15
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
16
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
17
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
18 Ramosetron Investigational Phase 4 132036-88-5
19 Gastrointestinal Agents Phase 4
20 Cathartics Phase 4
21 Laxatives Phase 4
22 Antacids Phase 4
23 Citrate Phase 4
24 Chelating Agents Phase 4
25 Picosulfate sodium Phase 4
26 Anticoagulants Phase 4
27 Anti-Ulcer Agents Phase 4
28 Calcium, Dietary Phase 4
29 Anti-Infective Agents Phase 4
30 beta-Lactamase Inhibitors Phase 4
31 Antitubercular Agents Phase 4
32 Disinfectants Phase 4
33 Chlorhexidine gluconate Phase 4
34 Anti-Infective Agents, Local Phase 4
35 Antiemetics Phase 4
36 Amoxicillin-Potassium Clavulanate Combination Phase 4
37 Peripheral Nervous System Agents Phase 4
38 Autonomic Agents Phase 4
39 Cholinergic Antagonists Phase 4
40
Glycopyrrolate Phase 4 596-51-0 3494
41 Adjuvants, Anesthesia Phase 4
42 Muscarinic Antagonists Phase 4
43 Cholinesterase Inhibitors Phase 4
44 Anti-Bacterial Agents Phase 4
45 Antibiotics, Antitubercular Phase 4
46 Anesthetics Phase 4
47 Neuromuscular Nondepolarizing Agents Phase 4
48 Analgesics, Non-Narcotic Phase 4
49 Narcotics Phase 4
50 Adrenergic alpha-2 Receptor Agonists Phase 4

Interventional clinical trials:

(show top 50) (show all 159)
# Name Status NCT ID Phase Drugs
1 Phase IV, Prospective, Randomized Study Comparing Preparation the Day Before and Split-dose Regimen With Sodium Picosulphate/Magnesium Citrate for Morning Colonoscopies Unknown status NCT01481714 Phase 4 Sodium picosulphate, magnesium oxid and citric acid;Sodium picosulphate/magnesium oxide and citric acid
2 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
3 The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy Completed NCT01402622 Phase 4 Propofol anesthesia
4 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
5 Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life Completed NCT02258763 Phase 4 Amoxicillin-Potassium Clavulanate Combination;Placebo
6 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Recruiting NCT02862314 Phase 4
7 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial Active, not recruiting NCT02861131 Phase 4 Sugammadex;Neostigmine
8 Eliminating Use of Non Depolarizing Neuromuscular Blocking Agents to Reduce Postoperative Pulmonary Complications: A Multi-center, Randomized Control Trial Not yet recruiting NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
9 A Randomized Placebo Controlled Trial of Low Dose Angiotensin Converting Enzyme Inhibitor to Prevent Pneumonia in Older People Who Require Tube Feeding Because of Neurological Dysphagia Terminated NCT02358642 Phase 4 Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
10 Efficacy and Cost Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Locally Advanced Head and Neck Cancer to Prevent Aspiration Pneumonia. A Randomized Phase II-III Study Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
11 Phase 2/3 Application of Botulinum Neurotoxin Type A in Salivary Glands as a Treatment of Chronic Drooling in Patients With Cerebral Palsy: A Controlled Clinical Trial. Unknown status NCT01489904 Phase 2, Phase 3
12 Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
13 Venticute in Patients With Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Ventilation, and Severe Oxygenation Impairment: A Randomized, Multinational, Multicenter, Parallel Group, Double Blind, Control Group Study Completed NCT00074906 Phase 3 Venticute
14 Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial Completed NCT02080754 Phase 3
15 A Randomised Controlled Trial of Dysphagia Therapies for Swallowing Disorders Following Stroke. Completed NCT00257764 Phase 2, Phase 3
16 The Effects of Bronchodilator Therapy On Respiratory and Autonomic Function in Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
17 Muscle Preservation and Swallow Function Following Radiotherapy: A Dose Response Study Completed NCT01279837 Phase 2, Phase 3
18 Esophageal Stent is More Effective Than Tamponade Controlling Refractory Esophageal Variceal Bleeding: a Randomized Controlled Trial Completed NCT01242280 Phase 3
19 Survey of Miglustat Therapeutic Effects on Neurological and Systemic Symptoms of Infantile Type of Sandhoff and Taysachs Diseases Recruiting NCT03822013 Phase 3 Miglustat
20 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
21 Calfactant Therapy for Direct Acute Respiratory Distress Syndrome & Direct Acute Lung Injury in Adults and Children Terminated NCT00682500 Phase 3 Calfactant;Room Air (placebo)
22 The Randomized Inhaled Nitric Oxide Study (NINOS) in Full-Term and Nearly Full-Term Infants With Hypoxic Respiratory Failure Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
23 Early Inhaled Nitric Oxide Therapy in Term and Near Term Infants With Respiratory Failure Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
24 Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Terminated NCT00016523 Phase 3 Inhaled nitric oxide;Placebo
25 Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia Terminated NCT01971320 Phase 3
26 Regular Versus Liquid Diet as the First Meal in Patients Undergoing Major Abdominal Gynecologic Cancer Operation: A Randomized Controlled Trial Withdrawn NCT00328757 Phase 3
27 Effect of Daikenchuto (TJ-100) on Intestinal Dysmotility and For the Prevention of Postoperative Paralytic Ileus in Patients Undergoing Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-Controlled Phase II Trial Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
28 Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging Completed NCT03050957 Phase 2
29 Effectiveness of a New Neuromuscular Electrical Stimulation (NMES) Treatment Technique (VitalStim® Therapy) in the Management of Young Infants With Severe Dysphagia: a Prospective Pilot Study Completed NCT01723358 Phase 2
30 A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients Completed NCT00568698 Phase 1, Phase 2 Hydroxyurea
31 Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia (OD). A Randomized Controlled Trial. Completed NCT01777672 Phase 2
32 Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia Completed NCT01085903 Phase 2 Modafinil;Placebo
33 Aromatherapy for Postoperative Nausea and Vomiting in Children: A Single Blind Randomized Clinical Trial Completed NCT02663154 Phase 2 Aromatherapy inhaler;Saline inhaler
34 Induction of Volitional Swallowing in Chronic Dysphagia Post Stroke: A Novel Mechanism-Based Intervention Completed NCT00306501 Phase 2
35 Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts Completed NCT00773227 Phase 2
36 Cough and Swallow Rehabilitation Following Stroke Completed NCT01907321 Phase 1, Phase 2 Measures performed on all subjects
37 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial Recruiting NCT02927691 Phase 2
38 Establishing Normal Swallowing and Breathing Profiles in Healthy Adults Across the Age Span Recruiting NCT03122145 Phase 1, Phase 2 Capsaicin
39 The Nutritional Supplement Phosphatidylserine in Patients With Familial Recruiting NCT02276716 Phase 2 Phosphatidylserine
40 Therapeutic Impact of tDCS on Dysphagia in the Acute Phase of Stroke / Impact thérapeutique de la tDCS Sur la Dysphagie en Phase Aigue de l'Accident Vasculaire cérébral Active, not recruiting NCT01758991 Phase 1, Phase 2
41 Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI) Active, not recruiting NCT02819479 Phase 2 25% Mannitol;Low-dose Intra-arterial Bevacizumab
42 Effect Of Early Initiation Of Noninvasive Positive Pressure Ventilation On ICU Length Of Stay In Children With Status Asthmaticus, A Prospective Randomized Trial Withdrawn NCT01403428 Phase 2
43 A Randomised Placebo Controlled Trial to Explore the Effectiveness of Botulinum Toxin Injection at Reducing Oral Secretions and Frequency of Tracheal Suctioning in Tracheotomised Patients. Withdrawn NCT00973999 Phase 2 Botulinum Toxin
44 Comparison of GERD and the Effects of Anti-Reflux Therapy on Pulmonary Function Between Able-Bodied and SCI Individuals Unknown status NCT02584751 Phase 1 Omeprazole
45 Airway Protection Deficits According to Stimulus Type in Parkinson's Disease Completed NCT02390089 Phase 1 Capsaicin vapor
46 PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients: a Feasibility Study Not yet recruiting NCT03723291 Phase 1
47 Dynamic Laryngotracheal Separation for Aspiration. Prevention of Silent Aspiration Pneumonia During Swallowing by an Implanted Stimulator Suspended NCT00580346 Phase 1
48 Validation of a Marker for Aspiration and Endotracheal Tube Cuff Leak. Withdrawn NCT02301845 Phase 1 Diatoms Shells
49 Salivary Alpha Amylase Bronchial Measure for Early Aspiration Pneumonia Diagnosis in Patients Treated With Therapeutic Hypothermia After Out-of-hospital Cardiac Arrest. Unknown status NCT03007862
50 Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation Unknown status NCT03108430

Search NIH Clinical Center for Aspiration Pneumonia

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Prednisolone

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 29

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

41
Lung, Brain, Colon, Testes, Tongue, Liver, Spinal Cord

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 3868)
# Title Authors PMID Year
1
Aspiration pneumonia and primary lung abscess: diagnosis and therapy of an aerobic or an anaerobic infection? 9 38
20477271 2007
2
Effects of the rotigotine transdermal patch versus oral levodopa on swallowing in patients with Parkinson's disease. 38
31323520 2019
3
Conversion to Gastrojejunostomy Tubes in Developmentally Disabled Children Intolerant to Gastrostomy Tube Feeding. 38
31107798 2019
4
Chronic radiation-associated dysphagia in oropharyngeal cancer survivors: Towards age-adjusted dose constraints for deglutitive muscles. 38
31341972 2019
5
A New Fully Covered Irradiation Stent Versus a Partially Covered Irradiation Stent for Unresectable Malignant Dysphagia: A Single-Center Experience. 38
31144010 2019
6
Effectiveness and safety of perioperative enteral feeding in patients with burn injuries: a systematic review protocol. 38
30889069 2019
7
Impact of the Hospitalist System in Japan on the Quality of Care and Healthcare Economics. 38
31391388 2019
8
Enhancement of swallowing motor activity by the ACE inhibitor imidapril in an arterially perfused rat preparation. 38
31421086 2019
9
Is the modified Mann Assessment of Swallowing Ability useful for assessing dysphagia in patients with mild to moderate dementia? 38
31416733 2019
10
Safety and effectiveness of endoscopic mucosal resection or endoscopic submucosal dissection for gastric neoplasia within 2 days' hospital stay. 38
31393357 2019
11
Anesthesia for peroral endoscopic myotomy in Japan. 38
30994477 2019
12
Laparoscopic fundoplication for a child with abdominal intrathecal Baclofen pump. 38
31430037 2019
13
Flavin adenine dinucleotide synthase deficiency due to FLAD1 mutation presenting as multiple acyl-CoA dehydrogenation deficiency-like disease: A case report. 38
30982706 2019
14
Esophageal intramural pseudodiverticulosis complicated with severe stricture requiring surgical resection. 38
30697669 2019
15
Fascia lata graft closure of an enlarged tracheoesophageal puncture (TEP) after laryngectomy/laryngopharyngectomy. 38
31076881 2019
16
Predictors of Penetration-Aspiration in Parkinson's Disease Patients With Dysphagia: A Retrospective Analysis. 38
30939890 2019
17
Gerstmann-Sträussler-Scheinker syndrome misdiagnosed as conversion disorder. 38
31413052 2019
18
Dentures discovered in larynx 8 days after general anaesthetic. 38
31406002 2019
19
Predictive value of a novel pragmatic tool for post-stroke aspiration risk: The Functional Bedside Aspiration Screen. 38
31348609 2019
20
Oropharyngeal dysphagia among patients newly discharged to nursing home care after an episode of hospital care. 38
31332709 2019
21
Endoscopic Nasoenteral Feeding Tube Fixation with Hemoclip Reduces Tube Dislodgement. 38
31367879 2019
22
Mortality of four captive-born crested screamer chicks (Chauna torquata). 38
31360650 2019
23
Calf Circumference Is a Useful Index for Assessing Dysphagia among Community Dwelling Elderly Recipients of Long-Term Care. 38
31366821 2019
24
Prevalence of drooling, swallowing, and feeding problems in cerebral palsy across the lifespan: a systematic review and meta-analyses. 38
31328797 2019
25
Aural stimulation with capsaicin prevented pneumonia in dementia patients. 38
31280931 2019
26
Cefepime challenge after piperacillin/tazobactam-induced thrombocytopenia. 38
30968302 2019
27
Convulsive status epilepticus due to different evolutionary stages of neurocysticercosis - solitary cyticercus granuloma, low cyst load, and single calcific lesion in an endemic country: Clinical profile. 38
31419720 2019
28
[Intra- and postoperative complications classified according to the Clavien-Dindo classification in patients > 80 years after transurethral resection of the urinary bladder]. 38
29518819 2019
29
A Pilot Study of Pharyngeal Electrical Stimulation for Orally Intubated ICU Patients with Dysphagia. 38
31313142 2019
30
Removal of a Trigger Cord Stuck between Bands during Endoscopic Multiple-Band Ligation for Treating Esophageal Variceal Hemorrhage. 38
31337195 2019
31
Carcinoma cervix with cerebellar metastases presenting with pulmonary aspiration: a rare presentation and a rare metastatic site in a common cancer. 38
31352376 2019
32
Aspiration Pneumonia in Older Adults. 38
30794136 2019
33
A phase III, multicenter, prospective, single-blinded, noninferiority, randomized controlled trial on the performance of a novel esophageal stent with an antireflux valve (with video). 38
30684601 2019
34
Routine monitoring of gastric residual for prevention of necrotising enterocolitis in preterm infants. 38
31425604 2019
35
A case of esophageal cancer with human immunodeficiency virus infection that progressed rapidly after neoadjuvant chemoradiotherapy. 38
31352645 2019
36
Change in tongue pressure and the related factors after esophagectomy: a short-term, longitudinal study. 38
30941604 2019
37
Beta-sarcoglycan-deficient muscular dystrophy presenting as chronic bronchopneumonia in a young cat. 38
31308955 2019
38
Economic costs of dysphagia among hospitalized patients. 38
31314145 2019
39
Aspiration Pneumonia: a Shadow in Post-Bariatric Patient : Correlation between aspiration and minigrastric bypass. 38
31332615 2019
40
Food bolus-forming ability predicts incidence of aspiration pneumonia in nursing home older adults: a prospective observational study. 38
31299094 2019
41
A Double-Blind Randomized Controlled Trial to Determine the Preventive Effect of Hangekobokuto on Aspiration Pneumonia in Patients Undergoing Cardiovascular Surgery. 38
31316037 2019
42
Outcome of two variations of a surgical technique performed for canine unilateral arytenoid lateralisation. 38
31292275 2019
43
The effect of repetitive transcranial magnetic stimulation combined with traditional dysphagia therapy on poststroke dysphagia: a pilot double-blinded randomized-controlled trial. 38
30676426 2019
44
Dysphagia screening and risks of pneumonia and adverse outcomes after acute stroke: An international multicenter study. 38
31226922 2019
45
Is discard better than return gastric residual aspirates: a systematic review and meta-analysis. 38
31253100 2019
46
Rates of Dysphagia-Related Diagnoses in Long-Term Survivors of Head and Neck Cancers. 38
31184260 2019
47
Presbyphagia to Dysphagia: Multiple Perspectives and Strategies for Quality Care of Older Adults. 38
31158906 2019
48
Pulmonary Complications of Opioid Overdose Treated With Naloxone. 38
31182316 2019
49
Laryngotracheal separation in pediatric patients: 13-year experience in a reference service. 38
31166409 2019
50
RETROSPECTIVE ANALYSIS OF MORTALITY IN CAPTIVE BONGO (TRAGELAPHUS EURYCERUS), 1995-2015. 38
31260193 2019

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6
# Gene Variation Type Significance SNP ID GRCh37 Pos GRCh38 Pos
1 CHAT NM_020549.4(CHAT): c.2081C> G (p.Ser694Cys) single nucleotide variant Pathogenic rs201439531 10:50872926-50872926 10:49664880-49664880
2 CHAT NM_020549.4(CHAT): c.1061C> T (p.Thr354Met) single nucleotide variant Conflicting interpretations of pathogenicity rs769234940 10:50835781-50835781 10:49627735-49627735

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 TAC1 MMP8 ITGAM IL17A ATP4A ALB

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of nitric oxide biosynthetic process GO:0045429 9.49 TRPV1 MMP8
2 potassium ion import across plasma membrane GO:1990573 9.48 ATP4A ATP12A
3 cellular response to nerve growth factor stimulus GO:1990090 9.46 TRPV1 TAC1
4 ATP hydrolysis coupled proton transport GO:0015991 9.43 ATP4A ATP12A
5 response to pain GO:0048265 9.4 TRPV1 TAC1
6 microglial cell activation GO:0001774 9.37 TRPV1 ITGAM
7 cellular sodium ion homeostasis GO:0006883 9.32 ATP4A ATP12A
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP4A ATP12A
9 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
10 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
11 positive regulation of microglial cell activation GO:1903980 8.62 MMP8 ITGAM

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP4A ATP12A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Aspiration Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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