MCID: ASP007
MIFTS: 48

Aspiration Pneumonia

Categories: Gastrointestinal diseases, Infectious diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 74 29 6 15 71
Pneumonia, Aspiration 43 17
Aspiration Pneumonitis 71
Pneumonia Aspiration 54

Classifications:



External Ids:

Disease Ontology 12 DOID:0050152
MeSH 43 D011015
SNOMED-CT 67 422588002
ICD10 32 J69.0
UMLS 71 C0032290 C1761609

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to eclampsia and aspiration pneumonitis. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are Folate Metabolism and amb2 Integrin signaling. The drugs Sodium citrate and Magnesium oxide have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and testes, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 74 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 686)
# Related Disease Score Top Affiliating Genes
1 eclampsia 32.1 IL6 F2 ALB ACE
2 aspiration pneumonitis 32.0 TEF SLC22A4 SERPINA3 F3 CRP ATP4A
3 gastroesophageal reflux 31.0 IL6 CHAT ATP4A ATP12A
4 lung abscess 30.9 LACTB IL6 CRP ALB
5 pleural empyema 30.8 F2 CRP ALB
6 bronchiolitis 30.8 IL6 IL17A CRP
7 bronchopneumonia 30.6 SERPINA3 IL6 CRP ALB
8 periodontitis, chronic 30.4 MMP8 IL6
9 pulmonary edema 30.4 PIK3C2A F2 CRP ACE
10 peptic ulcer disease 30.3 ATP4A ATP12A ALB
11 cerebrovascular disease 30.3 SERPINA3 IL6 F2 CRP ACE
12 esophageal disease 30.3 TEF ATP4A ATP12A ALB
13 gastritis 30.2 ITGAM IL6 IL17A ATP4A
14 bronchitis 30.2 TAC1 LACTB IL6 CRP ALB
15 covid-19 30.2 IL6 CRP ACE
16 peptic esophagitis 30.2 IL6 ATP4A ATP12A ALB
17 laryngeal disease 30.2 MMP8 ATP4A ATP12A
18 cranial nerve palsy 30.2 CRP ALB ACE
19 klebsiella pneumonia 30.2 LACTB IL17A CRP ALB
20 viral pneumonia 30.1 IL6 IL17A CRP
21 ileus 30.1 IL6 IL17A F2 CRP
22 volvulus of midgut 30.1 CRP ATP4A ATP12A ALB
23 bacterial pneumonia 30.1 SERPINA3 LACTB IL6 IL17A CRP ALB
24 common cold 30.1 IL6 IL17A ALB
25 left bundle branch hemiblock 30.1 PIK3C2A CRP ACE
26 periodontitis 30.0 SERPINA3 MMP8 IL6 IL17A CRP
27 severe acute respiratory syndrome 30.0 IL6 CRP ACE
28 pneumonia 30.0 PIK3C2A MMP8 LACTB ITGAM IL6 IL17A
29 mycobacterium tuberculosis 1 30.0 SERPINA3 ITGAM IL17A CRP
30 vasculitis 30.0 SERPINA3 ITGAM IL6 IL17A CRP
31 hernia, hiatus 30.0 TEF SLC22A4 CRP ATP4A ATP12A
32 hepatic coma 30.0 F3 F2 ALB
33 gastroenteritis 29.9 LACTB IL6 CRP ALB
34 bronchiolitis obliterans 29.9 MMP8 IL6 IL17A CRP
35 sleep disorder 29.9 IL6 CRP ACE
36 duodenal obstruction 29.9 TEF CRP ATP4A ATP12A ALB
37 newborn respiratory distress syndrome 29.9 SLC22A4 IL6 CRP
38 vascular dementia 29.9 SERPINA3 IL6 CRP CHAT ACE
39 uremia 29.9 ITGAM IL6 CRP ALB ACE
40 acute pancreatitis 29.8 SERPINA3 IL6 CRP ALB
41 polyneuropathy 29.8 IL6 CRP ALB ACE
42 pulmonary embolism 29.8 F3 F2 CRP ALB ACE
43 hepatic encephalopathy 29.8 IL6 F2 ATP12A ALB
44 gas gangrene 29.8 SERPINA3 PIK3C2A IL6 CRP
45 otitis media 29.8 LACTB IL6 IL17A CRP ALB
46 bacterial infectious disease 29.8 SERPINA3 ITGAM IL6 IL17A CRP
47 myositis 29.8 SERPINA3 PIK3C2A IL6 IL17A
48 myocarditis 29.7 PIK3C2A IL6 IL17A ACE
49 neutropenia 29.7 LACTB ITGAM IL6 CRP ALB
50 portal hypertension 29.6 F3 F2 ALB ACE

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

MGI Mouse Phenotypes related to Aspiration Pneumonia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10 ACE ALB CHAT CRP F2 F3
2 homeostasis/metabolism MP:0005376 9.91 ACE ALB ATP12A ATP4A CHAT CRP
3 digestive/alimentary MP:0005381 9.76 ALB ATP12A ATP4A CHAT F2 IL17A
4 immune system MP:0005387 9.4 ACE ALB ATP4A CRP F2 F3

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 190)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sodium citrate Approved, Investigational Phase 4 68-04-2
2
Magnesium oxide Approved Phase 4 1309-48-4 14792
3
Magnesium citrate Approved Phase 4 3344-18-1
4
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
5
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
7
Desflurane Approved Phase 4 57041-67-5 42113
8 Poractant alfa Approved Phase 4 129069-19-8
9
Remifentanil Approved Phase 4 132875-61-7 60815
10
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
11
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
12
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
13
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
14
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
15
Succinylcholine Approved Phase 4 306-40-1 5314
16
Lisinopril Approved, Investigational Phase 4 76547-98-3, 83915-83-7 5362119
17
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
18
Ramosetron Investigational Phase 4 132036-88-5
19 Gastrointestinal Agents Phase 4
20 Antacids Phase 4
21 Anti-Ulcer Agents Phase 4
22 Cathartics Phase 4
23 Citrate Phase 4
24 Chelating Agents Phase 4
25 Laxatives Phase 4
26 Anticoagulants Phase 4
27 Calcium, Dietary Phase 4
28 Picosulfate sodium Phase 4
29 Anti-Infective Agents Phase 4
30 beta-Lactamase Inhibitors Phase 4
31 Anti-Infective Agents, Local Phase 4
32 Disinfectants Phase 4
33 Cholinesterase Inhibitors Phase 4
34
Glycopyrrolate Phase 4 596-51-0 3494
35 Amoxicillin-Potassium Clavulanate Combination Phase 4
36 Pulmonary Surfactants Phase 4
37 Narcotics Phase 4
38 Anti-Bacterial Agents Phase 4
39 Antibiotics, Antitubercular Phase 4
40 Anesthetics Phase 4
41 Adrenergic alpha-Agonists Phase 4
42 Excitatory Amino Acid Antagonists Phase 4
43 Anesthetics, Dissociative Phase 4
44 Vasoconstrictor Agents Phase 4
45 Analgesics Phase 4
46 Anesthetics, General Phase 4
47 Analgesics, Opioid Phase 4
48 Adrenergic Agents Phase 4
49 Analgesics, Non-Narcotic Phase 4
50 Hypnotics and Sedatives Phase 4

Interventional clinical trials:

(show top 50) (show all 177)
# Name Status NCT ID Phase Drugs
1 Phase IV, Prospective, Randomized Study Comparing Preparation the Day Before and Split-dose Regimen With Sodium Picosulphate/Magnesium Citrate for Morning Colonoscopies Unknown status NCT01481714 Phase 4 Sodium picosulphate, magnesium oxid and citric acid;Sodium picosulphate/magnesium oxide and citric acid
2 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Completed NCT02862314 Phase 4
3 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
4 Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management Completed NCT01710891 Phase 4
5 The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy Completed NCT01402622 Phase 4 Propofol anesthesia
6 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial Completed NCT02861131 Phase 4 Sugammadex;Neostigmine
7 Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life Completed NCT02258763 Phase 4 Amoxicillin-Potassium Clavulanate Combination;Placebo
8 Stress Assessment in Preterm Infants With Respiratory Distress Syndrome Treated or Not With an Analgesic Drug During the Traditional or the Less Invasive Method of Surfactant Therapy. Not yet recruiting NCT04073173 Phase 4 Analgesic, Opioid
9 Eliminating Use of Non Depolarizing Neuromuscular Blocking Agents to Reduce Postoperative Pulmonary Complications: A Multi-center, Randomized Control Trial Suspended NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
10 A Randomized Placebo Controlled Trial of Low Dose Angiotensin Converting Enzyme Inhibitor to Prevent Pneumonia in Older People Who Require Tube Feeding Because of Neurological Dysphagia Terminated NCT02358642 Phase 4 Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
11 Efficacy and Cost Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Locally Advanced Head and Neck Cancer to Prevent Aspiration Pneumonia. A Randomized Phase II-III Study Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
12 Phase 2/3 Application of Botulinum Neurotoxin Type A in Salivary Glands as a Treatment of Chronic Drooling in Patients With Cerebral Palsy: A Controlled Clinical Trial. Unknown status NCT01489904 Phase 2, Phase 3
13 Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
14 Venticute in Patients With Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Ventilation, and Severe Oxygenation Impairment: A Randomized, Multinational, Multicenter, Parallel Group, Double Blind, Control Group Study Completed NCT00074906 Phase 3 Venticute
15 Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial Completed NCT02080754 Phase 3
16 A Randomised Controlled Trial of Dysphagia Therapies for Swallowing Disorders Following Stroke. Completed NCT00257764 Phase 2, Phase 3
17 The Effects of Bronchodilator Therapy On Respiratory and Autonomic Function in Patients With Familial Dysautonomia Completed NCT01987219 Phase 3 Albuterol-sulphate;Ipratropium-bromide
18 Muscle Preservation and Swallow Function Following Radiotherapy: A Dose Response Study Completed NCT01279837 Phase 2, Phase 3
19 Esophageal Stent is More Effective Than Tamponade Controlling Refractory Esophageal Variceal Bleeding: a Randomized Controlled Trial Completed NCT01242280 Phase 3
20 Survey of Miglustat Therapeutic Effects on Neurological and Systemic Symptoms of Infantile Type of Sandhoff and Taysachs Diseases Recruiting NCT03822013 Phase 3 Miglustat
21 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
22 Calfactant Therapy for Direct Acute Respiratory Distress Syndrome & Direct Acute Lung Injury in Adults and Children Terminated NCT00682500 Phase 3 Calfactant;Room Air (placebo)
23 The Randomized Inhaled Nitric Oxide Study (NINOS) in Full-Term and Nearly Full-Term Infants With Hypoxic Respiratory Failure Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
24 Early Inhaled Nitric Oxide Therapy in Term and Near Term Infants With Respiratory Failure Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
25 Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Terminated NCT00016523 Phase 3 Inhaled nitric oxide;Placebo
26 Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia Terminated NCT01971320 Phase 3
27 Regular Versus Liquid Diet as the First Meal in Patients Undergoing Major Abdominal Gynecologic Cancer Operation: A Randomized Controlled Trial Withdrawn NCT00328757 Phase 3
28 Effect of Daikenchuto (TJ-100) on Intestinal Dysmotility and For the Prevention of Postoperative Paralytic Ileus in Patients Undergoing Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-Controlled Phase II Trial Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
29 Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI) Unknown status NCT02819479 Phase 2 25% Mannitol;Low-dose Intra-arterial Bevacizumab
30 Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging Completed NCT03050957 Phase 2
31 A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients Completed NCT00568698 Phase 1, Phase 2 Hydroxyurea;Placebo to match hydroxyurea
32 Effectiveness of a New Neuromuscular Electrical Stimulation (NMES) Treatment Technique (VitalStim® Therapy) in the Management of Young Infants With Severe Dysphagia: a Prospective Pilot Study Completed NCT01723358 Phase 2
33 Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia Completed NCT01085903 Phase 2 Modafinil;Placebo
34 Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia (OD). A Randomized Controlled Trial. Completed NCT01777672 Phase 2
35 Establishing Normal Swallowing and Breathing Profiles in Healthy Adults Across the Age Span Completed NCT03122145 Phase 1, Phase 2 Capsaicin
36 Aromatherapy for Postoperative Nausea and Vomiting in Children: A Single Blind Randomized Clinical Trial Completed NCT02663154 Phase 2 Aromatherapy inhaler;Saline inhaler
37 Induction of Volitional Swallowing in Chronic Dysphagia Post Stroke: A Novel Mechanism-Based Intervention Completed NCT00306501 Phase 2
38 Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts Completed NCT00773227 Phase 2
39 Cough and Swallow Rehabilitation Following Stroke Completed NCT01907321 Phase 1, Phase 2 Measures performed on all subjects
40 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial Recruiting NCT02927691 Phase 2
41 The Nutritional Supplement Phosphatidylserine in Patients With Familial Recruiting NCT02276716 Phase 2 Phosphatidylserine
42 Therapeutic Impact of tDCS on Dysphagia in the Acute Phase of Stroke / Impact thérapeutique de la tDCS Sur la Dysphagie en Phase Aigue de l'Accident Vasculaire cérébral Active, not recruiting NCT01758991 Phase 1, Phase 2
43 Effect Of Early Initiation Of Noninvasive Positive Pressure Ventilation On ICU Length Of Stay In Children With Status Asthmaticus, A Prospective Randomized Trial Withdrawn NCT01403428 Phase 2
44 A Randomised Placebo Controlled Trial to Explore the Effectiveness of Botulinum Toxin Injection at Reducing Oral Secretions and Frequency of Tracheal Suctioning in Tracheotomised Patients. Withdrawn NCT00973999 Phase 2 Botulinum Toxin
45 Comparison of GERD and the Effects of Anti-Reflux Therapy on Pulmonary Function Between Able-Bodied and SCI Individuals Unknown status NCT02584751 Phase 1 Omeprazole
46 Airway Protection Deficits According to Stimulus Type in Parkinson's Disease Completed NCT02390089 Phase 1 Capsaicin vapor
47 PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients: a Feasibility Study Not yet recruiting NCT03723291 Phase 1
48 Dynamic Laryngotracheal Separation for Aspiration. Prevention of Silent Aspiration Pneumonia During Swallowing by an Implanted Stimulator Suspended NCT00580346 Phase 1
49 Validation of a Marker for Aspiration and Endotracheal Tube Cuff Leak. Withdrawn NCT02301845 Phase 1 Diatoms Shells
50 Salivary Alpha Amylase Bronchial Measure for Early Aspiration Pneumonia Diagnosis in Patients Treated With Therapeutic Hypothermia After Out-of-hospital Cardiac Arrest. Unknown status NCT03007862

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 29

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

40
Lung, Brain, Testes, Colon, Tongue, Liver, Spinal Cord

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 4086)
# Title Authors PMID Year
1
Aspiration pneumonia and primary lung abscess: diagnosis and therapy of an aerobic or an anaerobic infection? 54 61
20477271 2007
2
Clinicopathological findings of a long-term survivor of V180I genetic Creutzfeldt-Jakob disease. 61
32178563 2020
3
Is There an Upper Age Limit for Bariatric Surgery? Laparoscopic Gastric Bypass Outcomes in Septuagenarians. 61
32152838 2020
4
Aspiration Pneumonia or COVID-19 Infection: A Diagnostic Challenge. 61
32381329 2020
5
Management of children with tuberculous broncho-esophageal fistulae. 61
32275811 2020
6
Use of an Ultra-slim Gastroscope to Accomplish Endoscopist-Facilitated Rescue Intubation During ERCP: A Novel Approach to Enhance Patient and Staff Safety. 61
32504349 2020
7
Indications for non-invasive ventilation in respiratory failure. 61
32493199 2020
8
Miniplate-Augmented Interlaminar Fusion in C1-C2 Screwing. 61
32173550 2020
9
Pulmonary complications in dogs with acute presentation of pancreatitis. 61
32571307 2020
10
Management of dysphagia in Huntington's disease: a descriptive review. 61
31989345 2020
11
Obstruction-related dysphagia in inclusion body myositis: Cricopharyngeal bar on videofluoroscopy indicates risk of aspiration. 61
32172012 2020
12
Myopathies featuring early or prominent dysphagia. 61
32510670 2020
13
Characterization of Dysphagia and Longitudinal Changes in Swallowing Function in Adults with Niemann-Pick Disease Type C Treated with Miglustat. 61
32562141 2020
14
Safety of withholding intubation in gamma-hydroxybutyrate- and gamma-butyrolactone-intoxicated coma patients in the emergency department. 61
31815871 2020
15
Oropharyngeal Dysphagia and Aspiration Pneumonia Following Coronavirus Disease 2019: A Case Report. 61
32533346 2020
16
A 95-year-old patient with unexpected coronavirus disease 2019 masked by aspiration pneumonia: a case report. 61
32576232 2020
17
Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study. 61
32478453 2020
18
An Autopsy Case of Idiopathic Pleuroparenchymal Fibroelastosis with Left Vocal Cord Paralysis and a Rapid Deterioration without an Acute Exacerbation. 61
32188804 2020
19
Consideration of Cough Reflex Development When Ordering Modified Barium Swallow Studies in Infants. 61
31493070 2020
20
The cost-effectiveness of food consistency modification with xanthan gum-based Nutilis Clear® in patients with post-stroke dysphagia in Poland. 61
32552742 2020
21
The prevalence and findings of fibre-optic endoscopic evaluation of swallowing in hospitalised patients with dysphagia. 61
32479646 2020
22
Segmentation of cervical intervertebral disks in videofluorography by CNN, multi-channelization and feature selection. 61
32306186 2020
23
Pathologic Lesions of the Budgett Frog (Lepidobatrachus laevis), an Emerging Laboratory Animal Model. 61
32234112 2020
24
Dysphagia is associated with oral, physical, cognitive and psychological frailty in Japanese community-dwelling elderly persons. 61
31874118 2020
25
Value of robotic-assisted technique in redo gastrojejunostomy for severe stenosis after gastric bypass. 61
31463879 2020
26
Mechanism of dysphagia after acute traumatic cervical spinal cord injury. 61
32486896 2020
27
Comparing the Safety and Cost of Image-Guided Percutaneous Gastrostomy Tube Placement in the Outpatient Versus Overnight Observation Setting in a Single-Center Retrospective Study. 61
32527708 2020
28
Cardiothoracic Patients with Unilateral Vocal Fold Paralysis: Pneumonia Rates Following Injection Laryngoplasty. 61
32506947 2020
29
Delayed diagnosis of fatal pneumonic canine plague: clinical and pathologic features in two naturally infected Colorado dogs. 61
32450913 2020
30
Palliative care and infection management at end of life in nursing homes: A descriptive survey. 61
32153248 2020
31
Salivary gland ablation: introducing an interventional radiology treatment alternative in the management of sialorrhea. 61
32198665 2020
32
A Sensory Stimulation Protocol to Modulate Cough Sensitivity: A Randomized Controlled Trial Safety Study. 61
32379483 2020
33
Percutaneous transhepatic endoscopic lithotripsy of biliary stones with holmium laser for the treatment of recurrent cholangitis. 61
32367249 2020
34
Brachycephalic airway syndrome: management of post-operative respiratory complications in 248 dogs. 61
32037517 2020
35
Echocardiographic and Clinical Follow-up After Aortic Valve Neocuspidization Using Autologous Pericardium. 61
32458022 2020
36
Silent microaspirations: The forerunner to the diagnosis of bulbar onset myasthenia gravis in a young woman. 61
32467548 2020
37
Bilateral Vocal Cord Immobility After Chemoradiotherapy For Nasopharyngeal Carcinoma. 61
32476655 2020
38
Dysphagia in Myositis: A Study of the Structural and Physiologic Changes Resulting in Disordered Swallowing. 61
31764229 2020
39
T4 cervical esophageal cancer cured with modern chemoradiotherapy: A case report. 61
32518786 2020
40
Exploratory study of clinical effectiveness and safety of TJ-116 bukuryoingohangekobokuto for anxiety and postoperative water brash in esophageal cancer patients (TJ116E). 61
32481404 2020
41
A case of simultaneous superficial hypopharyngeal and superficial esophageal cancers treated by endoscopic resection. 61
32475899 2020
42
Development of a tension pneumomediastinum during mechanical ventilation of a young Irish Wolfhound. 61
32147906 2020
43
Tracheostomy during COVID-19 pandemic-Novel approach. 61
32358855 2020
44
Bilateral vocal cord paralysis after endoscopic placement of fully covered self-expandable metal stent for palliative treatment of malignant proximal esophageal obstruction: two case reports. 61
32410595 2020
45
Postintubation Dysphagia During COVID-19 Outbreak-Contemporary Review. 61
32468193 2020
46
A proposed guideline for vagus nerve stimulator handling in palliative care and after death. 61
32463125 2020
47
Time Course and Recovery of the Movements of Hyoid Bone and Thyroid Cartilage During Swallowing in a Patient With Sarcopenic Dysphagia. 61
31058647 2020
48
Nasogastric Intubation as Health and Safety Risk in Equine Practice-A Questionnaire. 61
32303319 2020
49
Lateral conservative approach for recurrent/persistent hypopharyngeal carcinoma: a case series. 61
32367150 2020
50
A Pilot Study of Pharyngeal Electrical Stimulation for Orally Intubated ICU Patients with Dysphagia. 61
31313142 2020

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6 ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 CHAT NM_020549.4(CHAT):c.2081C>G (p.Ser694Cys)SNV Pathogenic 523529 rs201439531 10:50872926-50872926 10:49664880-49664880
2 CHAT NM_020549.4(CHAT):c.1061C>T (p.Thr354Met)SNV Conflicting interpretations of pathogenicity 523528 rs769234940 10:50835781-50835781 10:49627735-49627735

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

Pathways related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.35 SERPINA3 IL6 F2 CRP ALB
2 10.81 MYH2 ITGAM IL6

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 TAC1 SERPINA3 MMP8 IL6 IL17A F3
2 extracellular space GO:0005615 9.4 TAC1 SERPINA3 MMP8 ITGAM IL6 IL17A

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.55 TAC1 SERPINA3 IL6 IL17A CRP
2 positive regulation of neuroinflammatory response GO:0150078 9.4 MMP8 IL6
3 regulation of neuroinflammatory response GO:0150077 9.37 MMP8 IL6
4 negative regulation of lipid storage GO:0010888 9.32 IL6 CRP
5 neutrophil mediated immunity GO:0002446 9.26 IL6 ACE
6 regulation of microglial cell activation GO:1903978 8.96 MMP8 IL6
7 acute-phase response GO:0006953 8.92 SERPINA3 IL6 F2 CRP

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Aspiration Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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