MCID: ASP007
MIFTS: 49

Aspiration Pneumonia

Categories: Gastrointestinal diseases, Infectious diseases, Respiratory diseases

Aliases & Classifications for Aspiration Pneumonia

MalaCards integrated aliases for Aspiration Pneumonia:

Name: Aspiration Pneumonia 12 74 29 6 15 71
Pneumonia, Aspiration 44 17
Aspiration Pneumonitis 71
Pneumonia Aspiration 54

Classifications:



External Ids:

Disease Ontology 12 DOID:0050152
MeSH 44 D011015
SNOMED-CT 67 47839005
ICD10 32 J69.0
UMLS 71 C0032290 C1761609

Summaries for Aspiration Pneumonia

Disease Ontology : 12 A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has symptom tachypnea and has symptom cough.

MalaCards based summary : Aspiration Pneumonia, also known as pneumonia, aspiration, is related to eclampsia and aspiration pneumonitis, and has symptoms including cough and tachypnea. An important gene associated with Aspiration Pneumonia is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are Folate Metabolism and amb2 Integrin signaling. The drugs Chlorhexidine and Remifentanil have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and tongue, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 74 Aspiration pneumonia is a type of lung infection that is due to a relatively large amount of material... more...

Related Diseases for Aspiration Pneumonia

Diseases related to Aspiration Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 762)
# Related Disease Score Top Affiliating Genes
1 eclampsia 32.0 F2 ALB ACE
2 aspiration pneumonitis 31.8 SERPINA3 F3 CRP ATP4A ATP12A ALB
3 lung abscess 30.9 LACTB IL6 CRP ALB
4 bronchiolitis 30.7 IL6 IL17A CRP
5 pneumonia 30.6 PIK3C2A LACTB ITGAM IL6 IL17A GPT
6 cerebrovascular disease 30.5 SERPINA3 IL6 F2 CRP ACE
7 pulmonary edema 30.5 PIK3C2A F2 CRP ACE
8 adult respiratory distress syndrome 30.5 ITGAM IL6 F2 ACE
9 hernia, hiatus 30.4 CRP ATP4A ATP12A
10 ileus 30.3 IL6 F2 CRP
11 periodontitis 30.3 SERPINA3 IL6 IL17A CRP
12 bronchitis 30.3 TAC1 LACTB IL6 CRP ALB
13 pleural empyema 30.2 IL6 GPT F2 CRP ALB
14 peptic esophagitis 30.2 IL6 ATP4A ATP12A ALB
15 viral pneumonia 30.1 IL6 IL17A CRP
16 cranial nerve palsy 30.1 CRP ALB ACE
17 bronchopneumonia 30.1 SERPINA3 IL6 IL17A GPT CRP ALB
18 uremia 30.1 IL6 CRP ALB ACE
19 urinary tract infection 30.1 CRP ACE
20 common cold 30.1 IL6 IL17A ALB
21 bronchiolitis obliterans 30.1 IL6 IL17A CRP
22 severe acute respiratory syndrome 30.1 IL6 CRP ACE
23 left bundle branch hemiblock 30.1 PIK3C2A CRP ACE
24 duodenal obstruction 30.0 CRP ATP4A ATP12A ALB
25 supranuclear palsy, progressive, 1 30.0 SNCA SERPINA3 CHAT
26 vascular dementia 30.0 SERPINA3 IL6 CRP CHAT ACE
27 klebsiella pneumonia 30.0 IL6 IL17A CRP ALB
28 stroke, ischemic 30.0 SERPINA3 IL6 F3 F2 CRP ALB
29 gastroenteritis 29.9 LACTB IL6 CRP ALB
30 interstitial lung disease 29.9 IL6 IL17A CRP ALB
31 polyneuropathy 29.9 IL6 CRP ALB ACE
32 lipid pneumonia 29.9 NPC2 CRP
33 cardiac arrest 29.9 PIK3C2A GPT ALB ACE
34 pulmonary embolism 29.9 F3 F2 CRP ALB ACE
35 gas gangrene 29.9 SERPINA3 PIK3C2A IL6 CRP
36 bacterial infectious disease 29.8 SERPINA3 ITGAM IL6 IL17A CRP
37 vasculitis 29.8 SERPINA3 ITGAM IL6 IL17A CRP
38 myocarditis 29.8 PIK3C2A IL6 IL17A ACE
39 otitis media 29.8 LACTB IL6 IL17A CRP ALB
40 bacterial pneumonia 29.8 SERPINA3 LACTB IL6 IL17A GPT CRP
41 disease by infectious agent 29.8 SERPINA3 LACTB IL6 IL17A GPT CRP
42 toxic shock syndrome 29.8 IL6 F3 CRP
43 lung disease 29.7 SERPINA3 IL6 IL17A F3 CRP ALB
44 acute pancreatitis 29.7 SERPINA3 IL6 GPT CRP
45 hepatic encephalopathy 29.7 IL6 GPT F2 ALB
46 hepatic coma 29.7 GPT F3 F2 ALB
47 intracranial embolism 29.7 F3 F2 CRP ALB ACE
48 metabolic acidosis 29.7 IL6 GPT F2 ALB
49 congestive heart failure 29.6 PIK3C2A IL6 CRP ALB ACE
50 myositis 29.6 SNCA SERPINA3 PIK3C2A IL6 IL17A

Graphical network of the top 20 diseases related to Aspiration Pneumonia:



Diseases related to Aspiration Pneumonia

Symptoms & Phenotypes for Aspiration Pneumonia

Symptoms:

12
  • cough
  • tachypnea

MGI Mouse Phenotypes related to Aspiration Pneumonia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.18 ACE ALB CHAT CRP F2 F3
2 homeostasis/metabolism MP:0005376 10.09 ACE ALB ATP12A ATP4A CHAT CRP
3 growth/size/body region MP:0005378 10.07 ACE ATP12A ATP4A CHAT F2 F3
4 digestive/alimentary MP:0005381 9.92 ALB ATP12A ATP4A CHAT F2 IL17A
5 immune system MP:0005387 9.77 ACE ALB ATP4A CRP F2 F3
6 renal/urinary system MP:0005367 9.28 ACE ALB ATP12A IL17A IL6 PIK3C2A

Drugs & Therapeutics for Aspiration Pneumonia

Drugs for Aspiration Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 66)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
2
Remifentanil Approved Phase 4 132875-61-7 60815
3
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
4
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
5
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
6
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
7
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
8
Succinylcholine Approved Phase 4 306-40-1 5314
9 Anti-Infective Agents Phase 4
10 Disinfectants Phase 4
11 Anti-Infective Agents, Local Phase 4
12 Chlorhexidine gluconate Phase 4
13 Dermatologic Agents Phase 4
14 Anti-Bacterial Agents Phase 4
15 Anesthetics Phase 4
16 Antibiotics, Antitubercular Phase 4
17 Neurotransmitter Agents Phase 4
18 Adrenergic alpha-Agonists Phase 4
19 Hypnotics and Sedatives Phase 4
20 Analgesics, Non-Narcotic Phase 4
21 Neuromuscular Blocking Agents Phase 4
22 Analgesics, Opioid Phase 4
23 Excitatory Amino Acid Antagonists Phase 4
24 Analgesics Phase 4
25 Adrenergic Agents Phase 4
26 Anesthetics, Intravenous Phase 4
27 Anesthetics, Dissociative Phase 4
28 Neuromuscular Nondepolarizing Agents Phase 4
29 Anesthetics, General Phase 4
30 Adrenergic Agonists Phase 4
31 Vasoconstrictor Agents Phase 4
32
Amoxicillin Approved, Vet_approved Phase 2, Phase 3 26787-78-0 33613
33
Clavulanate Approved, Vet_approved Phase 2, Phase 3 58001-44-8 5280980
34
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
35
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
36
Moxifloxacin Approved, Investigational Phase 3 151096-09-2, 354812-41-2 152946
37
Sulbactam Approved Phase 3 68373-14-8
38
Ampicillin Approved, Vet_approved Phase 3 69-53-4 6249
39
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
40
Polyestradiol phosphate Approved Phase 3 28014-46-2
41
Nitric Oxide Approved Phase 3 10102-43-9 145068
42 Estradiol 3-benzoate Phase 3
43 Contraceptive Agents Phase 3
44 Contraceptives, Oral Phase 3
45 Contraceptives, Oral, Combined Phase 3
46 Estradiol 17 beta-cypionate Phase 3
47 beta-Lactamase Inhibitors Phase 3
48 Norgestimate, ethinyl estradiol drug combination Phase 3
49 Anti-Asthmatic Agents Phase 3
50 Respiratory System Agents Phase 3

Interventional clinical trials:

(show all 42)
# Name Status NCT ID Phase Drugs
1 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
2 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Completed NCT02862314 Phase 4
3 Eliminating Use of Non Depolarizing Neuromuscular Blocking Agents to Reduce Postoperative Pulmonary Complications: A Multi-center, Randomized Control Trial Suspended NCT03962725 Phase 4 Neuromuscular Blocking Agents;Anesthetic Adjuncts
4 Efficacy and Cost Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Locally Advanced Head and Neck Cancer to Prevent Aspiration Pneumonia. A Randomized Phase II-III Study Unknown status NCT01598402 Phase 2, Phase 3 amoxicillin/clavulanic acid suspension
5 Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia Completed NCT01045902 Phase 3 Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
6 Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial Completed NCT02080754 Phase 3
7 Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects Terminated NCT00000362 Phase 3
8 Early Inhaled Nitric Oxide Therapy in Term and Near Term Infants With Respiratory Failure Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
9 The Randomized Inhaled Nitric Oxide Study (NINOS) in Full-Term and Nearly Full-Term Infants With Hypoxic Respiratory Failure Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
10 Effect of Daikenchuto (TJ-100) on Intestinal Dysmotility and For the Prevention of Postoperative Paralytic Ileus in Patients Undergoing Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-Controlled Phase II Trial Unknown status NCT01607307 Phase 2 Oral/enteral TJ-100 solution;Oral/enteral placebo solution
11 Dynamic Laryngotracheal Separation for Aspiration. Prevention of Silent Aspiration Pneumonia During Swallowing by an Implanted Stimulator Suspended NCT00580346 Phase 1
12 Validation of a Marker for Aspiration and Endotracheal Tube Cuff Leak. Withdrawn NCT02301845 Phase 1 Diatoms Shells
13 Salivary Alpha Amylase Bronchial Measure for Early Aspiration Pneumonia Diagnosis in Patients Treated With Therapeutic Hypothermia After Out-of-hospital Cardiac Arrest. Unknown status NCT03007862
14 Preoperative Fasting for Ambulatory Cataract Surgery: A Time-Interrupted Prospective Study Unknown status NCT03828500
15 Mechanical Ventilation During Cardiac Surgery, a Randomized Controlled Trial Unknown status NCT02090205
16 Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation Unknown status NCT03108430
17 Measuring the Effects of a Music Therapy Protocol on Respiratory and Bulbar Functions of Patients With Early and Mid-stage Amyotrophic Lateral Sclerosis: Mixed Methods Single Case Study Series Unknown status NCT03604822
18 Cross Sectional Evaluation of Coughing Force in Stroke Patients With Severe Aspiration Completed NCT02080988
19 Evaluation du Dosage de l'Amylase Dans le Liquide Broncho Alveolaire Dans le Diagnostic précoce de la Pneumopathie d'Inhalation Infectieuse du Sujet Comateux intubé-ventilé. Completed NCT03182387
20 The Effect of Continuous vs Enteral Pump Feeding in Aspiration in Tube Fed Patients Completed NCT00164957
21 Evaluation of Gastric Residual Volume in Fasting Obese Patients Using Gastric Ultrasound: a Comparative Study Completed NCT04544371
22 Functionality and Accuracy of the smARTrack System in Real-Life ICU Settings Completed NCT02705781
23 Efficacy of Surface Landmark Palpation for Identification of the Cricoid Cartilage in Obstetric Patients Completed NCT02416219
24 Bedside Gastric Ultrasound for Preoperative Assessment of Gastric Content in Diabetic Patients Following ASA Fasting Guidelines Completed NCT04181814
25 Evaluation of the Effectiveness and Safety of an Own-invention System for Continuous Supraglottic Aspiration in Intubated and Mechanically Ventilated Patients: the "SUPRAtube" Device Completed NCT03573635
26 The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on Clinical Outcomes, Specifically the Incidence of Aspiration Pneumonia and Postoperative Length of Stay Completed NCT02858596
27 Syndrome and Aspiration Pneumonia in Intensive Care Completed NCT01881672
28 The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation: A Pilot Study Completed NCT01301352
29 Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery Completed NCT02779595
30 Perioperative Change of Regional Ventilation During Spontaneous Breathing Completed NCT02419196
31 Flexible Endoscopic Evaluation of Swallowing (FEES) to Determine Neurological Patients' Oral Diet Completed NCT03753841
32 Impact of a Strategy Based on the Unyvero® Testing System on Appropriate Antimicrobial Treatment in Patients With Suspected Aspiration Pneumonia Requiring Mechanical Ventilation : a Randomized Controlled Unblinded Trial Recruiting NCT03763799
33 Nutrition Monitoring and Feeding Optimization With the smART+ System Recruiting NCT04098224
34 Ultrasound Assessment of Metoclopramide Effect on Gastric Volume in Patients Undergoing Cesarean Section: A Randomized, Double-blind, Cross-sectional Study" Recruiting NCT04157998 normal saline;Metoclopramide 10mg
35 Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function Recruiting NCT04747691
36 Redefining Community Acquired Pneumonia in Older Adults: The Role and Impact of Aspiration Recruiting NCT04709978
37 Screen and Intervene : A Diagnostic Accuracy Study and A Randomized Controlled Trial for Postextubation Dysphagia Recruiting NCT03284892
38 Slow-Stream Expiratory Muscle Strength Training for Veterans With Dysphagia Living in Long-term Care Not yet recruiting NCT04064333
39 Nocturnal Nasal Continuous Positive Airway Pressure in Aspiration Pneumonia Terminated NCT03844568
40 Functionality and Accuracy of the smART System in Real-Life ICU Settings Terminated NCT03689985
41 Intra-laryngeal Implant for Treatment of Chronic Aspirations Withdrawn NCT03325725
42 Detection of Silent Aspiration Events Utilizing pH/Impedance Probes in Hospitalized Patients Withdrawn NCT02720029

Search NIH Clinical Center for Aspiration Pneumonia

Cochrane evidence based reviews: pneumonia, aspiration

Genetic Tests for Aspiration Pneumonia

Genetic tests related to Aspiration Pneumonia:

# Genetic test Affiliating Genes
1 Aspiration Pneumonia 29

Anatomical Context for Aspiration Pneumonia

MalaCards organs/tissues related to Aspiration Pneumonia:

40
Lung, Brain, Tongue, Liver, Thyroid, Heart, Bone

Publications for Aspiration Pneumonia

Articles related to Aspiration Pneumonia:

(show top 50) (show all 4265)
# Title Authors PMID Year
1
Aspiration pneumonia and primary lung abscess: diagnosis and therapy of an aerobic or an anaerobic infection? 61 54
20477271 2007
2
Esophageal Obstruction and Death in a Nonverbal Patient. 61
33583613 2021
3
Detection of associated bacteria in aspiration pneumonia and lung abscesses using partial 16S rRNA gene amplicon sequencing. 61
33540111 2021
4
Interventions to Prevent Aspiration Pneumonia in Older Adults: An Updated Systematic Review. 61
33405973 2021
5
Prevalence and Severity of Dysphagia Using Videofluoroscopic Swallowing Study in Patients with Aspiration Pneumonia. 61
33458798 2021
6
Predictive Value of the Pneumonia Severity Score on Mortality due to Aspiration Pneumonia. 61
33547167 2021
7
Myasthenia Gravis Associated With Programmed Death-1 (PD-1) Receptor Inhibitor Pembrolizumab: A 40-day Case Report. 61
33143531 2021
8
An autopsy case of corticobasal syndrome due to asymmetric degeneration of the motor cortex and substantia nigra with TDP-43 proteinopathy, associated with Alzheimer's disease pathology. 61
33537992 2021
9
Whipple's pancreaticoduodenectomy for cancer of the head of the pancreas in a patient with amyotrophic lateral sclerosis: perioperative challenges. 61
33185456 2021
10
The frequency of gastroesophageal reflux when radiofrequency catheter ablation procedures for atrial fibrillation under general anesthesia with a supraglottic device: Observational pilot study. 61
33578560 2021
11
Prevalence and Risk Factors of Dysphagia in Patients with Multiple Sclerosis. 61
33580368 2021
12
Clinicopathological findings of a mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes/Leigh syndrome overlap patient with a novel m.3482A>G mutation in MT-ND1. 61
33300189 2021
13
Clinical Factors Associated With Successful Gastrostomy Tube Weaning in Patients With Prolonged Dysphagia After Stroke. 61
33557480 2021
14
A Descriptive and Quantitative Immunohistochemical Study Demonstrating a Spectrum of Platelet Recruitment Patterns Across Pulmonary Infections Including COVID-19. 61
33174599 2021
15
New treatment of bronchopleural fistula following surgical resection of the dorsal segment of the left lower lobe: A case report. 61
33305506 2021
16
Effect of multi-professional education on the perceptions and awareness of oral health care among undergraduate nursing students in a nursing school. 61
33576016 2021
17
Neurophysiological monitoring of the laryngeal adductor reflex during cerebellar-pontine angle and brainstem surgery. 61
33272821 2021
18
Development of an Oral Care Multidisciplinary Initiative in an Acute Care Community Hospital: Framework, Timeline, and Outcomes. 61
33561350 2021
19
A case of esophageal achalasia presenting with empyema and septic shock differentiated from esophageal rupture. 61
33527334 2021
20
Evaluation of the pharynx and upper esophageal sphincter motility using high-resolution pharyngeal manometry for Parkinson's disease. 61
33421742 2021
21
Oral dysfunctions and cognitive impairment/dementia. 61
33164225 2021
22
[New aspects of rapid sequence induction including treatment of pulmonary aspiration]. 61
33410921 2021
23
First confirmed case of infant botulism in Africa, caused by a dual-toxin-producing Clostridium botulinum strain. 61
33212262 2021
24
Oral feeding for infants and children receiving nasal continuous positive airway pressure and high flow nasal cannula: a systematic review. 61
33596866 2021
25
Assessment of the Clinical Pulmonary Infection Scores for prediction of ventilator associated pneumonia in patients with out of hospital cardiac arrest. 61
32962955 2021
26
Premature oral pre-shaping for feeding in elderly population with risk of aspiration pneumonia. 61
33556135 2021
27
Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review. 61
32677660 2021
28
Prediction of oral intake recovery for inpatients with aspiration pneumonia by videoendoscopic evaluation using the Hyodo-Komagane score in Japan. 61
33025615 2021
29
Effectiveness of Water Jelly Ingestion for Both Rehabilitation and Prevention of Aspiration Pneumonia in Elderly Patients With Moderate to Severe Dysphagia. 61
33471491 2021
30
Risk Factors and Assessment Using an Endoscopic Scoring System for Postoperative Respiratory Complications after Anterior Cervical Decompression and Fusion Surgery. 61
33575489 2021
31
The Spectrum of Histopathologic Findings in Lungs of Patients With Fatal Coronavirus Disease 2019 (COVID-19) Infection. 61
32821902 2021
32
Aerodigestive Disease in Dogs. 61
33131915 2021
33
The Modified Volume-Viscosity Swallow Test as a Predictor of Aspiration Pneumonia after Acute Ischemic Stroke. 61
33168332 2021
34
Evaluation of the therapeutic effect of high-flow nasal cannula oxygen therapy on patients with aspiration pneumonia accompanied by respiratory failure in the post-stroke sequelae stage. 61
33413281 2021
35
Posterior circulation stroke presenting as a new continuous cough: not always COVID-19. 61
33431481 2021
36
Immediate Effects of Sensorimotor Training in Airway Protection (smTAP) on Cough Outcomes in Progressive Supranuclear Palsy: A Feasibility Study. 61
33515312 2021
37
Clinical features and outcome of patients with primary central nervous system lymphoma admitted to the intensive care unit: a French national expert center experience. 61
33452932 2021
38
Dysphagia: Evaluation and Collaborative Management. 61
33448766 2021
39
CHARGE syndrome in the era of molecular diagnosis: Similar outcomes in those without coloboma or choanal atresia. 61
33189935 2021
40
Videofluoroscopy, CT angiography, and ultrasonography of congenital esophageal stenosis in a Labrador retriever. 61
30590864 2021
41
Effect of Daikenchuto for mechanically ventilated patients with enteral feeding intolerance: a propensity score-matched analysis using a nationwide administrative inpatient database. 61
33483948 2021
42
Fatal coccidioidomycosis involving the lungs, brain, tongue, and adrenals in a cirrhotic patient. An autopsy case. 61
33532240 2021
43
Glyphosate poisoning - a case report. 61
33533750 2021
44
Effects of conservative treatment of 2-week rigorous bed rest on muscle disuse atrophy in osteoporotic vertebral fracture patients. 61
33442429 2021
45
Video-Assisted Thoracoscopic Surgery for Re-Collapse of Vertebrae after Percutaneous Vertebral Augmentation (PVA). 61
33575492 2021
46
Construction of a Mutant in Prevotella melaninogenica Using the Conjugation Transfer Method with Escherichia coli. 61
32815125 2021
47
Hemorrhaging from an Intramedullary Cavernous Malformation Diagnosed due to Recurrent Pneumonia and Diffuse Aspiration Bronchiolitis. 61
33281156 2020
48
Hypoxaemia and interstitial lung disease in an infant with hypothyroidism and hypotonia. 61
33370995 2020
49
Primary cardiac hemangiosarcoma in a horse: echocardiographic and necropsy findings. 61
33176251 2020
50
Aspiration of periodontopathic bacteria due to poor oral hygiene potentially contributes to the aggravation of COVID-19. 61
33177276 2020

Variations for Aspiration Pneumonia

ClinVar genetic disease variations for Aspiration Pneumonia:

6
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 CHAT NM_020549.4(CHAT):c.1061C>T (p.Thr354Met) SNV Pathogenic 523528 rs769234940 10:50835781-50835781 10:49627735-49627735
2 CHAT NM_020549.4(CHAT):c.2081C>G (p.Ser694Cys) SNV Pathogenic 523529 rs201439531 10:50872926-50872926 10:49664880-49664880

Expression for Aspiration Pneumonia

Search GEO for disease gene expression data for Aspiration Pneumonia.

Pathways for Aspiration Pneumonia

Pathways related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.35 SERPINA3 IL6 F2 CRP ALB
2 10.81 MYH2 ITGAM IL6

GO Terms for Aspiration Pneumonia

Cellular components related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 TAC1 SNCA SERPINA3 NPC2 IL6 IL17A
2 external side of plasma membrane GO:0009897 9.55 TRPV1 ITGAM IL17A F2 ACE
3 extracellular space GO:0005615 9.47 TAC1 SNCA SERPINA3 NPC2 ITGAM IL6

Biological processes related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.67 SNCA IL6 F2 ALB
2 inflammatory response GO:0006954 9.43 TRPV1 TAC1 SERPINA3 IL6 IL17A CRP
3 neutrophil mediated immunity GO:0002446 9.4 IL6 ACE
4 microglial cell activation GO:0001774 9.33 TRPV1 SNCA ITGAM
5 negative regulation of lipid storage GO:0010888 9.32 IL6 CRP
6 negative regulation of dopamine metabolic process GO:0045963 9.26 SNCA ITGAM
7 acute-phase response GO:0006953 8.92 SERPINA3 IL6 F2 CRP

Molecular functions related to Aspiration Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Aspiration Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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