Aspiration Pneumonitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ASP008 MIFTS: 45	Aspiration Pneumonitis Categories: Respiratory diseases
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Aliases & Classifications for Aspiration Pneumonitis

MalaCards integrated aliases for Aspiration Pneumonitis:

Name: Aspiration Pneumonitis ¹² ¹⁵ ⁷¹

Mendelson's Syndrome Resulting from a Procedure ⁷¹

Pneumonitis Due to Fumes and/or Vapors ⁷¹

Aspiration Pneumonia ⁷¹

Chemical Pneumonitis ¹²

Mendelson's Syndrome ¹²

Toxic Pneumonitis ⁷¹

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the respiratory system

Lung diseases due to external agents

Pneumonitis due to solids and liquids

Pneumonitis due to food and vomit

Other diseases of the respiratory system

Postprocedural respiratory disorders, not elsewhere classified

Mendelson syndrome

Pregnancy, childbirth and the puerperium

Complications of labour and delivery

Complications of anaesthesia during labour and delivery

Aspiration pneumonitis due to anaesthesia during labour and delivery

External Ids:

Disease Ontology ¹² DOID:3240

MeSH ⁴³ D011015

SNOMED-CT ⁶⁷ 422588002

ICD10 ³² J69.0 J95.4 O74.0

UMLS ⁷¹ C0032290 C0264458 C0340150 more

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Summaries for Aspiration Pneumonitis

Disease Ontology : ¹² A pneumonia that is defined as an acute lung injury after the inhalation of foreign material such as regurgitated acidic gastric contents, petroleum products and laxative oils. This syndrome occurs in patients who have a marked disturbance of consciousness such as that resulting from a drug overdose, seizures, a massive cerebrovascular accident, or the use of anesthesia. Aspiration of gastric contents results in a chemical burn of the tracheobronchial tree and pulmonary parenchyma, causing an intense parenchymal inflammatory reaction. The disease has symptom non-productive cough, has symptom tachypnea, has symptom bronchospasm, has symptom bloody sputum, has symptom frothy sputum, or has symptom respiratory distress, 2-5 hrs after aspiration.

MalaCards based summary : Aspiration Pneumonitis, also known as mendelson's syndrome resulting from a procedure, is related to lipid pneumonia and aspiration pneumonia, and has symptoms including tachypnea, respiratory distress and bronchospasm. An important gene associated with Aspiration Pneumonitis is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Folate Metabolism and AGE-RAGE signaling pathway in diabetic complications. The drugs Sodium citrate and Magnesium oxide have been mentioned in the context of this disorder. Affiliated tissues include lung, tongue and testes, and related phenotypes are digestive/alimentary and homeostasis/metabolism

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Related Diseases for Aspiration Pneumonitis

Diseases related to Aspiration Pneumonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 504)

#	Related Disease	Score	Top Affiliating Genes
1	lipid pneumonia	32.4	SP110 COPA
2	aspiration pneumonia	31.3	TEF SLC22A4 SERPINA3 F3 CRP ATP4A
3	tracheomalacia	30.0	TEF SLC22A4 ATP4A ATP12A
4	bronchiolitis obliterans	29.4	TNF CXCL8 CRP
5	bronchitis	29.3	TNF CXCL8 CRP ALB
6	pulmonary edema	29.3	TNF OXT CXCL8 CRP
7	constipation	29.2	TNF CRP ATP4A ATP12A ALB
8	bronchiolitis	29.2	TNF CXCL8 CRP
9	intracranial hypertension	29.2	TNF SERPINA3 F3 ALB
10	bronchopneumonia	29.1	TNF SERPINA3 CXCL8 CRP ALB
11	bronchiectasis	29.0	TNF SERPINA3 CXCL8 CRP
12	gastroesophageal reflux	28.7	TNF HRH2 CXCL8 ATP4A ATP12A
13	pneumonia	28.4	TNF HRH2 F3 CXCL8 CRP ALB
14	peptic ulcer disease	28.3	TNF HRH2 CXCL8 ATP4A ATP12A ALB
15	respiratory failure	28.3	TNF SERPINA3 F3 CXCL8 CRP ALB
16	pulmonary disease, chronic obstructive	28.1	TNF SERPINA3 CXCL8 CRP ATP4A ATP12A
17	exanthem	27.9	TNF F3 CXCL8 CRP ATP4A ATP12A
18	lung disease	27.9	TNF SERPINA3 F3 CXCL8 CRP COPA
19	vagus nerve disease	10.5	ATP4A ATP12A
20	hemangioma of intra-abdominal structure	10.5	ATP4A ATP12A
21	acquired gastric outlet stenosis	10.5	ATP4A ATP12A
22	displacement of cardia through esophageal hiatus	10.5	ATP4A ATP12A
23	angiodysplasia of intestine	10.5	ATP4A ATP12A
24	benzylpenicillin allergy	10.5	ATP4A ATP12A
25	granulomatous gastritis	10.5	ATP4A ATP12A
26	bacterial esophagitis	10.5	ATP4A ATP12A
27	lingual goiter	10.5	ATP4A ATP12A
28	gastrojejunal ulcer	10.5	ATP4A ATP12A
29	laryngeal tuberculosis	10.5	ATP4A ATP12A
30	fungal esophagitis	10.5	ATP4A ATP12A
31	dieulafoy lesion	10.5	ATP4A ATP12A
32	cervix erosion	10.5	ATP4A ATP12A
33	gastric gastrinoma	10.5	ATP4A ATP12A
34	cefuroxime allergy	10.5	ATP4A ATP12A
35	chronic intestinal vascular insufficiency	10.5	ATP4A ATP12A
36	rumination disorder	10.5	ATP4A ATP12A
37	acute laryngitis	10.5	ATP4A ATP12A
38	gastroduodenitis	10.5	ATP4A ATP12A
39	internal hemorrhoid	10.5	ATP4A ATP12A
40	scalp dermatosis	10.5	ATP4A ATP12A
41	central nervous system origin vertigo	10.5	ATP4A ATP12A
42	lymphocytic gastritis	10.5	ATP4A ATP12A
43	x-linked chondrodysplasia punctata 1	10.5	ATP4A ATP12A
44	eosinophilic gastritis	10.4	ATP4A ATP12A
45	gastric antral vascular ectasia	10.4	ATP4A ATP12A
46	functional diarrhea	10.4	ATP4A ATP12A
47	chronic duodenal ileus	10.4	CRP ALB
48	diarrhea 1, secretory chloride, congenital	10.4	ATP4A ATP12A
49	barbiturate abuse	10.4	ATP4A ATP12A
50	tuberculous peritonitis	10.4	CRP ALB

Graphical network of the top 20 diseases related to Aspiration Pneumonitis:

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Symptoms & Phenotypes for Aspiration Pneumonitis

Symptoms:

¹²

• tachypnea
• respiratory distress
• bronchospasm

• non-productive cough
• bloody sputum
• frothy sputum

MGI Mouse Phenotypes related to Aspiration Pneumonitis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.5	ALB ATP12A ATP4A HRH2 OXT SLC22A4
2	homeostasis/metabolism	MP:0005376	9.36	ALB ATP12A ATP4A CRP F3 HRH2

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Drugs & Therapeutics for Aspiration Pneumonitis

Drugs for Aspiration Pneumonitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 190)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Sodium citrate

Approved, Investigational

Phase 4

68-04-2

Magnesium oxide

Approved

Phase 4

1309-48-4

14792

Magnesium citrate

Approved

Phase 4

3344-18-1

Fentanyl

Approved, Illicit, Investigational, Vet_approved

Phase 4

437-38-7

3345

Clavulanate

Approved, Vet_approved

Phase 4

58001-44-8

5280980

Amoxicillin

Approved, Vet_approved

Phase 4

26787-78-0

33613

Propofol

Approved, Investigational, Vet_approved

Phase 4

2078-54-8

4943

Desflurane

Approved

Phase 4

57041-67-5

42113

Neostigmine

Approved, Vet_approved

Phase 4

59-99-4

4456

Remifentanil

Approved

Phase 4

132875-61-7

60815

Poractant alfa

Approved

Phase 4

129069-19-8

Lisinopril

Approved, Investigational

Phase 4

76547-98-3, 83915-83-7

5362119

Citric acid

Approved, Nutraceutical, Vet_approved

Phase 4

77-92-9

311

Ramosetron

Investigational

Phase 4

132036-88-5

Gastrointestinal Agents

Phase 4

Anti-Ulcer Agents

Phase 4

Antacids

Phase 4

Citrate

Phase 4

Cathartics

Phase 4

Chelating Agents

Phase 4

Laxatives

Phase 4

Anticoagulants

Phase 4

Calcium, Dietary

Phase 4

Picosulfate sodium

Phase 4

Anti-Bacterial Agents

Phase 4

Anti-Infective Agents

Phase 4

Antibiotics, Antitubercular

Phase 4

beta-Lactamase Inhibitors

Phase 4

Hypnotics and Sedatives

Phase 4

Anesthetics, General

Phase 4

Anesthetics, Intravenous

Phase 4

Cholinesterase Inhibitors

Phase 4

Glycopyrrolate

Phase 4

596-51-0

3494

Amoxicillin-Potassium Clavulanate Combination

Phase 4

Analgesics

Phase 4

Pulmonary Surfactants

Phase 4

Narcotics

Phase 4

Analgesics, Opioid

Phase 4

Cardiotonic Agents

Phase 4

Antihypertensive Agents

Phase 4

Angiotensin-Converting Enzyme Inhibitors

Phase 4

protease inhibitors

Phase 4

HIV Protease Inhibitors

Phase 4

Protective Agents

Phase 4

Calcium

Nutraceutical

Phase 4

7440-70-2

271

Ampicillin

Approved, Vet_approved

Phase 3

69-53-4

6249

Sulbactam

Approved

Phase 3

68373-14-8

Estradiol

Approved, Investigational, Vet_approved

Phase 3

50-28-2

5757

Norgestimate

Approved, Investigational

Phase 3

35189-28-7

6540478

Moxifloxacin

Approved, Investigational

Phase 3

354812-41-2, 151096-09-2

152946

Interventional clinical trials:

(show top 50) (show all 166)

#	Name	Status	NCT ID	Phase	Drugs
1	Phase IV, Prospective, Randomized Study Comparing Preparation the Day Before and Split-dose Regimen With Sodium Picosulphate/Magnesium Citrate for Morning Colonoscopies	Unknown status	NCT01481714	Phase 4	Sodium picosulphate, magnesium oxid and citric acid;Sodium picosulphate/magnesium oxide and citric acid
2	Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management	Completed	NCT01710891	Phase 4
3	The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy	Completed	NCT01402622	Phase 4	Propofol anesthesia
4	PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration	Completed	NCT02862314	Phase 4
5	The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial	Completed	NCT02861131	Phase 4	Sugammadex;Neostigmine
6	Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life	Completed	NCT02258763	Phase 4	Amoxicillin-Potassium Clavulanate Combination;Placebo
7	Stress Assessment in Preterm Infants With Respiratory Distress Syndrome Treated or Not With an Analgesic Drug During the Traditional or the Less Invasive Method of Surfactant Therapy.	Not yet recruiting	NCT04073173	Phase 4	Analgesic, Opioid
8	A Randomized Placebo Controlled Trial of Low Dose Angiotensin Converting Enzyme Inhibitor to Prevent Pneumonia in Older People Who Require Tube Feeding Because of Neurological Dysphagia	Terminated	NCT02358642	Phase 4	Angiotensin converting enzyme inhibitor (Lisinopril);Placebo
9	Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration	Unknown status	NCT00312507	Phase 3	Bovine Lipid Extract Surfactant (administered by lavage);Bovine Lipid Extract Surfactant (administered by bolus)
10	Efficacy and Cost Efficacy of Prophylactic Treatment With Antibiotics During Concomitant Chemoradiotherapy in Patients With Locally Advanced Head and Neck Cancer to Prevent Aspiration Pneumonia. A Randomized Phase II-III Study	Unknown status	NCT01598402	Phase 2, Phase 3	amoxicillin/clavulanic acid suspension
11	Phase 2/3 Application of Botulinum Neurotoxin Type A in Salivary Glands as a Treatment of Chronic Drooling in Patients With Cerebral Palsy: A Controlled Clinical Trial.	Unknown status	NCT01489904	Phase 2, Phase 3
12	Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia	Completed	NCT01045902	Phase 3	Avelox (Moxifloxacin, BAY12-8039);Sulbactam/Ampicillin
13	A Randomised Controlled Trial of Dysphagia Therapies for Swallowing Disorders Following Stroke.	Completed	NCT00257764	Phase 2, Phase 3
14	Sellick Maneuver Evaluation in Rapid Sequence Induction of General Anesthesia Non Inferiority Trial	Completed	NCT02080754	Phase 3
15	The Effects of Bronchodilator Therapy On Respiratory and Autonomic Function in Patients With Familial Dysautonomia	Completed	NCT01987219	Phase 3	Albuterol-sulphate;Ipratropium-bromide
16	Muscle Preservation and Swallow Function Following Radiotherapy: A Dose Response Study	Completed	NCT01279837	Phase 2, Phase 3
17	Esophageal Stent is More Effective Than Tamponade Controlling Refractory Esophageal Variceal Bleeding: a Randomized Controlled Trial	Completed	NCT01242280	Phase 3
18	Survey of Miglustat Therapeutic Effects on Neurological and Systemic Symptoms of Infantile Type of Sandhoff and Taysachs Diseases	Recruiting	NCT03822013	Phase 3	Miglustat
19	Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia	Terminated	NCT01971320	Phase 3
20	Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects	Terminated	NCT00000362	Phase 3
21	Regular Versus Liquid Diet as the First Meal in Patients Undergoing Major Abdominal Gynecologic Cancer Operation: A Randomized Controlled Trial	Withdrawn	NCT00328757	Phase 3
22	Effect of Daikenchuto (TJ-100) on Intestinal Dysmotility and For the Prevention of Postoperative Paralytic Ileus in Patients Undergoing Pancreaticoduodenectomy: A Multicenter, Randomized, Placebo-Controlled Phase II Trial	Unknown status	NCT01607307	Phase 2	Oral/enteral TJ-100 solution;Oral/enteral placebo solution
23	Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI)	Unknown status	NCT02819479	Phase 2	25% Mannitol;Low-dose Intra-arterial Bevacizumab
24	Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging	Completed	NCT03050957	Phase 2
25	A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients	Completed	NCT00568698	Phase 1, Phase 2	Hydroxyurea;Placebo to match hydroxyurea
26	Effectiveness of a New Neuromuscular Electrical Stimulation (NMES) Treatment Technique (VitalStim® Therapy) in the Management of Young Infants With Severe Dysphagia: a Prospective Pilot Study	Completed	NCT01723358	Phase 2
27	Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia	Completed	NCT01085903	Phase 2	Modafinil;Placebo
28	Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia (OD). A Randomized Controlled Trial.	Completed	NCT01777672	Phase 2
29	Establishing Normal Swallowing and Breathing Profiles in Healthy Adults Across the Age Span	Completed	NCT03122145	Phase 1, Phase 2	Capsaicin
30	Aromatherapy for Postoperative Nausea and Vomiting in Children: A Single Blind Randomized Clinical Trial	Completed	NCT02663154	Phase 2	Aromatherapy inhaler;Saline inhaler
31	Induction of Volitional Swallowing in Chronic Dysphagia Post Stroke: A Novel Mechanism-Based Intervention	Completed	NCT00306501	Phase 2
32	Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts	Completed	NCT00773227	Phase 2
33	Cough and Swallow Rehabilitation Following Stroke	Completed	NCT01907321	Phase 1, Phase 2	Measures performed on all subjects
34	Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial	Recruiting	NCT02927691	Phase 2
35	The Nutritional Supplement Phosphatidylserine in Patients With Familial	Recruiting	NCT02276716	Phase 2	Phosphatidylserine
36	Therapeutic Impact of tDCS on Dysphagia in the Acute Phase of Stroke / Impact thérapeutique de la tDCS Sur la Dysphagie en Phase Aigue de l'Accident Vasculaire cérébral	Active, not recruiting	NCT01758991	Phase 1, Phase 2
37	Effect Of Early Initiation Of Noninvasive Positive Pressure Ventilation On ICU Length Of Stay In Children With Status Asthmaticus, A Prospective Randomized Trial	Withdrawn	NCT01403428	Phase 2
38	A Randomised Placebo Controlled Trial to Explore the Effectiveness of Botulinum Toxin Injection at Reducing Oral Secretions and Frequency of Tracheal Suctioning in Tracheotomised Patients.	Withdrawn	NCT00973999	Phase 2	Botulinum Toxin
39	Comparison of GERD and the Effects of Anti-Reflux Therapy on Pulmonary Function Between Able-Bodied and SCI Individuals	Unknown status	NCT02584751	Phase 1	Omeprazole
40	Airway Protection Deficits According to Stimulus Type in Parkinson's Disease	Completed	NCT02390089	Phase 1	Capsaicin vapor
41	PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients: a Feasibility Study	Not yet recruiting	NCT03723291	Phase 1
42	Dynamic Laryngotracheal Separation for Aspiration. Prevention of Silent Aspiration Pneumonia During Swallowing by an Implanted Stimulator	Suspended	NCT00580346	Phase 1
43	Salivary Alpha Amylase Bronchial Measure for Early Aspiration Pneumonia Diagnosis in Patients Treated With Therapeutic Hypothermia After Out-of-hospital Cardiac Arrest.	Unknown status	NCT03007862
44	Continuous EtCO2 Monitoring in Acute Self Poisoned Patients Admitted in an Emergency Department	Unknown status	NCT01800123
45	Comparative Study of the Effect of Three Different Analgesic Techniques on the Incidence of Postoperative Nausea and Vomiting After Scleral Buckling Under General Anesthesia	Unknown status	NCT03313479		Dexmedetomidine
46	Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation	Unknown status	NCT03108430
47	Establish Comprehensive Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment	Unknown status	NCT02243722
48	A Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation and Chemotherapy	Unknown status	NCT00536952	Early Phase 1	Pulmozyme;Placebo
49	Incidence of Dysphagia in Intensive Care Patients With Tracheostomy Using High Resolution Pharyngoesophageal Manometry and Impedance	Unknown status	NCT02874352
50	Ultrasound Assessment of Gastric Content and Gastric Volume Before Crash Induction for Appendectomy	Unknown status	NCT02983175

Search NIH Clinical Center for Aspiration Pneumonitis

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Genetic Tests for Aspiration Pneumonitis

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Anatomical Context for Aspiration Pneumonitis

MalaCards organs/tissues related to Aspiration Pneumonitis:

⁴⁰

Lung, Tongue, Testes, Brain, Liver, Cortex, Spinal Cord

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Publications for Aspiration Pneumonitis

Articles related to Aspiration Pneumonitis:

(show top 50) (show all 534)

#	Title	Authors	PMID	Year
1	Perioperative Stroke and Readmissions Rates in Noncardiac Non-Neurologic Surgery. ⁶¹	Raman N...Thirumala PD	32280000	2020
2	First case of paralytic ileus after endoscopic mucosal resection of caecal polyp. ⁶¹	Khan Z...Nawras A	32423855	2020
3	An observational cohort study of numbers and causes of preventable general hospital admissions in people with and without intellectual disabilities in England. ⁶¹	Glover G...Oyinlola J	32141168	2020
4	Chronic Aspiration Pneumonitis Caused by Spontaneous Cerebrospinal Fluid Fistulae of the Skull Base. ⁶¹	Or M...Zada G	32449957	2020
5	Effects of Sugammadex on Post-Operative Pulmonary Complications in Laparoscopic Gastrectomy: A Retrospective Cohort Study. ⁶¹	Han J...Oh AY	32344750	2020
6	Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent. ⁶¹	Isoardi KZ...Isbister GK	32336161	2020
7	Nursing Home-Associated Pneumonia, Part I: Diagnosis. ⁶¹	Mylotte JM	31178286	2020
8	Increased severity associated with tallowamine in acute glyphosate poisoning. ⁶¹	Langrand J...Pulce C	31169038	2020
9	Choking agents and chlorine gas - History, pathophysiology, clinical effects and treatment. ⁶¹	Zellner T...Eyer F	31811912	2020
10	Burden and spectrum of paediatric respiratory diseases at a referral hospital in North-Central Nigeria - A five year review. ⁶¹	Ibraheem RM...Johnson WBR	32161704	2020
11	[Barium contrast aspiration pneumonitis]. ⁶¹	Tarrazo Tarrazo C...Maderuelo Riesco I	32173044	2020
12	Dysphagia Screening for Pneumonia Prevention in a Cancer Hospital: Results of a Quality/Safety Initiative. ⁶¹	Ebersole B...Jamal N	31791195	2020
13	Aspiration Pneumonitis Causing Respiratory Collapse in a Pregnant Patient Not in Labor. ⁶¹	Lozada MJ...Pacheco LD	31977784	2020
14	Adverse respiratory outcomes among head and neck cancer survivors in the Utah Cancer Survivors Study. ⁶¹	Kawakita D...Hashibe M	31721181	2020
15	Liquid Mosquito Repellent Ingestion in Children. ⁶¹	Reddy MV...Baranwal AK	31768860	2020
16	Pulmonary Complications of Opioid Overdose Treated With Naloxone. ⁶¹	Farkas A...Martin-Gill C	31182316	2020
17	Invasive Aspergillosis After Non-Fatal Drowning. ⁶¹	Koide S...Yamashita H	32210640	2020
18	Kerosene, Camphor, and Naphthalene Poisoning in Children. ⁶¹	Kumar S...Angurana SK	32021004	2019
19	Respiratory complications and 30-day unplanned hospital readmissions in patients with epilepsy. ⁶¹	Parikh R...Stapleton R	31750026	2019
20	Aspiration Pneumonitis Causing Respiratory Collapse in a Pregnant Patient Not in Labor. ⁶¹	Westerfield KL...Green S	31503154	2019
21	Indiscriminate Use of Antibiotics in Neurotrauma Patients Referred for Expert Neurosurgical Care in a Developing Country. ⁶¹	Oyemolade TA...Adeleye AO	31831986	2019
22	The Effect of S-Adenosylmethionine Treatment on Neurobehavioral Phenotypes in Lesch-Nyhan Disease: A Case Report. ⁶¹	Momosaki K...Nakamura K	31607891	2019
23	Diffuse Villous Tumor Arising in Barrett's Esophagus Presenting With Aspiration Pneumonitis. ⁶¹	Kaila V...Feldman M	31737717	2019
24	Obstructive retrosternal goitre mimicking severe bronchial asthma in pregnancy. ⁶¹	Loo GH...Azman M	31383679	2019
25	Predictive Factors of Postendoscopic Submucosal Dissection Electrocoagulation Syndrome and the Utility of Computed Tomography Scan after Esophageal Endoscopic Submucosal Dissection. ⁶¹	Yamaguchi H...Itoi T	31412351	2019
26	Spontaneous cerebrospinal fluid rhinorrhoea and aspiration pneumonitis following initiation of continuous positive airway pressure treatment for obstructive sleep apnoea. ⁶¹	Wasgewatta SL...Heraganahally SS	31139415	2019
27	Inflammasome-Independent and Atypical Processing of IL-1β Contributes to Acid Aspiration-Induced Acute Lung Injury. ⁶¹	Mizushina Y...Takahashi M	31109954	2019
28	Science and fiction in critical care: established concepts with or without evidence? ⁶¹	Westphal M	31200737	2019
29	Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial. ⁶¹	Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology...Wrigge H	31157366	2019
30	Myasthenic crisis following iodinated contrast material (iohexol) aspiration: a case report. ⁶¹	Bopeththa BVKM...Ralapanawa U	31146780	2019
31	Effect of Preemptive Acetaminophen Administered Within 1 Hour of General Anesthesia on Gastric Residual Volume and pH in Children. ⁶¹	Burke CN...Voepel-Lewis T	30270047	2019
32	Unusual case of intraoperative acute cor pulmonale during spine surgery. ⁶¹	Mohan B...Wander GS	30971611	2019
33	Preoperative fasting for ambulatory cataract surgery: asystematic review. ⁶¹	Popovic M...El-Defrawy S	30975334	2019
34	[Harmful biological agents in municipal waste thermal treatment plants]. ⁶¹	Cyprowski M	30653196	2019
35	Thin Patient, Fatty Liver. ⁶¹	Mukthinuthalapati VVPK...Gandhi SR	31058022	2019
36	Intravenous Sedation in Arnold-Chiari Malformation With Respiratory Failure. ⁶¹	Shionoya Y...Sunada K	30883227	2019
37	Accidental Pyrethroid Ingestion in Toddler: Near-Fatal Atypical Presentation and Successful Recovery. ⁶¹	Pallavidino M...Ramaiah AKH	31998671	2019
38	Explosive Vomiting Associated with Proximal Colonic Distention during a Difficult Propofol-Assisted Colonoscopy. ⁶¹	Rah KH...Tse J	31392065	2019
39	An autopsy based descriptive study of the spectrum of pulmonary lesions encountered in fetal deaths at a tertiary care center. ⁶¹	Neeha S...Patil AG	30303136	2018
40	Neuroleptic malignant syndrome in a young adult female at the university of Benin Teaching Hospital: a case report. ⁶¹	Agbonrofo PI...Osakue JE	30603012	2018
41	Prophylactic Antimicrobial Therapy for Acute Aspiration Pneumonitis. ⁶¹	Dragan V...Leis JA	29438467	2018
42	Airway obstruction due to sticky rice cake (mochi): a case series and review of the literature. ⁶¹	Nagata S...Norii T	31179924	2018
43	Fatal Diesel Poisoning: A Case Report and Brief Review of Literature. ⁶¹	Srinivasa Murthy A...Bheemanathi Hanuman S	29465462	2018
44	Hospital Inpatient Admissions With Dehydration and/or Malnutrition in Medicare Beneficiaries Receiving Enteral Nutrition: A Cohort Study. ⁶¹	Drake R...Braid-Forbes MJ	28636843	2018
45	Brain-stem hemangioblastomas: The seemingly innocuous lesion in a perilous location. ⁶¹	Joseph J...Jaiswal AK	29766943	2018
46	Let food be thy medicine and medicine be thy food? ⁶¹	Stauss M...Reynolds B	29992017	2018
47	[A Case of Treated with Laparoscopic Surgery for Intussusception Up to the Splenic Flexion Region Due to Cecum Cancer]. ⁶¹	Masuda G...Ishikawa T	29650919	2018
48	Will Maintenance of Oral Hygiene in Nursing Home Residents Prevent Pneumonia? ⁶¹	Mylotte JM	29266355	2018
49	Risk factors for maternal mortality associated with eclampsia presenting at a Nigerian tertiary hospital. ⁶¹	Rabiu KA...Alausa TG	30464647	2018
50	Percutaneous Endoscopic Gastrostomy in Ile-Ife, Nigeria:An Initial Report. ⁶¹	Alatise OI...Amusa YB	29607479	2018

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Genes for Aspiration Pneumonitis

Genes related to Aspiration Pneumonitis (0 elite genes):

(show all 15)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	SERPINA3	Serpin Family A Member 3	Protein Coding	7.23	DISEASES inferred ¹⁵ ¹⁵
2	ATP12A	ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit	Protein Coding	6.36	DISEASES inferred ¹⁵
3	ATP4A	ATPase H+/K+ Transporting Subunit Alpha	Protein Coding	6.36	DISEASES inferred ¹⁵
4	SLC22A4	Solute Carrier Family 22 Member 4	Protein Coding	6.24	DISEASES inferred ¹⁵
5	TEF	TEF Transcription Factor, PAR BZIP Family Member	Protein Coding	6.09	DISEASES inferred ¹⁵
6	CRP	C-Reactive Protein	Protein Coding	5.72	DISEASES inferred ¹⁵
7	HRH2	Histamine Receptor H2	Protein Coding	5.69	DISEASES inferred ¹⁵
8	ALB	Albumin	Protein Coding	5.44	DISEASES inferred ¹⁵
9	OXT	Oxytocin/Neurophysin I Prepropeptide	Protein Coding	5.12	DISEASES inferred ¹⁵
10	SP110	SP110 Nuclear Body Protein	Protein Coding	5.09	DISEASES inferred ¹⁵
11	COPA	COPI Coat Complex Subunit Alpha	Protein Coding	4.93	DISEASES inferred ¹⁵
12	TNF	Tumor Necrosis Factor	Protein Coding	4.9	DISEASES inferred ¹⁵
13	F3	Coagulation Factor III, Tissue Factor	Protein Coding	4.89	DISEASES inferred ¹⁵
14	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	4.84	DISEASES inferred ¹⁵
15	ZNF80	Zinc Finger Protein 80	Protein Coding	4.83	DISEASES inferred ¹⁵

Sources

Variations for Aspiration Pneumonitis

Sources

Expression for Aspiration Pneumonitis

Search GEO for disease gene expression data for Aspiration Pneumonitis.

Sources

Pathways for Aspiration Pneumonitis

Pathways related to Aspiration Pneumonitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Folate Metabolism ¹ Show member pathways Selenium Micronutrient Network ¹ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	11.79	TNF SERPINA3 CRP ALB
2	AGE-RAGE signaling pathway in diabetic complications ³⁶	11.43	TNF F3 CXCL8
3	Overview of nanoparticle effects ¹	10.08	TNF CXCL8 CRP
4	Secretion of Hydrochloric Acid in Parietal Cells ¹	9.65	HRH2 ATP4A

Sources

GO Terms for Aspiration Pneumonitis

Cellular components related to Aspiration Pneumonitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.56	TNF SERPINA3 OXT F3 CXCL8 CRP
2	extracellular space	GO:0005615	9.28	TNF SERPINA3 OXT F3 CXCL8 CRP

Biological processes related to Aspiration Pneumonitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sodium ion export across plasma membrane	GO:0036376	9.26	ATP4A ATP12A
2	cellular potassium ion homeostasis	GO:0030007	9.16	ATP4A ATP12A
3	establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	8.96	ATP4A ATP12A
4	negative regulation of lipid storage	GO:0010888	8.62	TNF CRP

Molecular functions related to Aspiration Pneumonitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	sodium:potassium-exchanging ATPase activity	GO:0005391	9.16	ATP4A ATP12A
2	potassium-transporting ATPase activity	GO:0008556	8.96	ATP4A ATP12A
3	potassium:proton exchanging ATPase activity	GO:0008900	8.62	ATP4A ATP12A

Sources

Sources for Aspiration Pneumonitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia