MCID: AST056
MIFTS: 18

Asthma-Related Traits 2

Categories: Genetic diseases, Immune diseases

Aliases & Classifications for Asthma-Related Traits 2

MalaCards integrated aliases for Asthma-Related Traits 2:

Name: Asthma-Related Traits 2 57 75
Asthma-Related Traits, Susceptibility to, 2 57 29 6 73
Asthma, Susceptibility to, 2 57 13
Asrt2 57 75
Asthma-Related Traits, Susceptibility to, Type 2 40
Asthma 2 57

Classifications:



External Ids:

OMIM 57 608584
MedGen 42 C1837811
MeSH 44 D001249
UMLS 73 C1837811

Summaries for Asthma-Related Traits 2

OMIM : 57 Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002). For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see 600807. (608584)

MalaCards based summary : Asthma-Related Traits 2, also known as asthma-related traits, susceptibility to, 2, is related to asthma and respiratory failure. An important gene associated with Asthma-Related Traits 2 is NPSR1 (Neuropeptide S Receptor 1). Affiliated tissues include testes.

UniProtKB/Swiss-Prot : 75 Asthma-related traits 2: Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis.

Related Diseases for Asthma-Related Traits 2

Diseases in the Asthma-Related Traits 1 family:

Asthma-Related Traits 2 Asthma-Related Traits 3
Asthma-Related Traits 4 Asthma-Related Traits 5
Asthma-Related Traits 6 Asthma-Related Traits 7
Asthma-Related Traits 8

Diseases related to Asthma-Related Traits 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 asthma 10.0
2 respiratory failure 9.5

Symptoms & Phenotypes for Asthma-Related Traits 2

Clinical features from OMIM:

608584

Drugs & Therapeutics for Asthma-Related Traits 2

Search Clinical Trials , NIH Clinical Center for Asthma-Related Traits 2

Genetic Tests for Asthma-Related Traits 2

Genetic tests related to Asthma-Related Traits 2:

# Genetic test Affiliating Genes
1 Asthma-Related Traits, Susceptibility to, 2 29 NPSR1

Anatomical Context for Asthma-Related Traits 2

MalaCards organs/tissues related to Asthma-Related Traits 2:

41
Testes

Publications for Asthma-Related Traits 2

Articles related to Asthma-Related Traits 2:

# Title Authors Year
1
Asthma 2 Oral Presentations. ( 27005360 )
2016
2
Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. ( 21820163 )
2011
3
Adherence and compliance in the management of asthma: 2. ( 10076216 )
1998
4
Practical aspects of aerosol therapy in asthma (2): Metered dose inhalers and spacers. ( 9164027 )
1997
5
Asthma: 2. Trends in pharmacologic therapy. ( 2880649 )
1987
6
Management of asthma. 2. Antiasthmatic drugs. ( 404636 )
1977
7
Acute respiratory failure due to asthma. 2. Diagnostic and therapeutic principles. ( 5566206 )
1971

Variations for Asthma-Related Traits 2

ClinVar genetic disease variations for Asthma-Related Traits 2:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 NPSR1 NM_207173.1(NPSR1): c.320A> T (p.Asn107Ile) single nucleotide variant risk factor rs324981 GRCh37 Chromosome 7, 34818113: 34818113
2 NPSR1 NM_207173.1(NPSR1): c.320A> T (p.Asn107Ile) single nucleotide variant risk factor rs324981 GRCh38 Chromosome 7, 34778501: 34778501

Expression for Asthma-Related Traits 2

Search GEO for disease gene expression data for Asthma-Related Traits 2.

Pathways for Asthma-Related Traits 2

GO Terms for Asthma-Related Traits 2

Sources for Asthma-Related Traits 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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