ASRT7
MCID: AST032
MIFTS: 13

Asthma-Related Traits 7 (ASRT7)

Categories: Genetic diseases, Immune diseases, Skin diseases

Aliases & Classifications for Asthma-Related Traits 7

MalaCards integrated aliases for Asthma-Related Traits 7:

Name: Asthma-Related Traits 7 57 72
Asthma-Related Traits, Susceptibility to, 7 57 29 13 6
Asrt7 57 72
Asthma-Related Traits, Susceptibility to, Type 7 39

Classifications:



External Ids:

OMIM® 57 611960
MeSH 44 D001249
MedGen 41 C2677770

Summaries for Asthma-Related Traits 7

OMIM® : 57 Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006). For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see 600807. (611960) (Updated 20-May-2021)

MalaCards based summary : Asthma-Related Traits 7, is also known as asthma-related traits, susceptibility to, 7. An important gene associated with Asthma-Related Traits 7 is CHI3L1 (Chitinase 3 Like 1).

UniProtKB/Swiss-Prot : 72 Asthma-related traits 7: Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis.

Related Diseases for Asthma-Related Traits 7

Symptoms & Phenotypes for Asthma-Related Traits 7

Clinical features from OMIM®:

611960 (Updated 20-May-2021)

Drugs & Therapeutics for Asthma-Related Traits 7

Search Clinical Trials , NIH Clinical Center for Asthma-Related Traits 7

Genetic Tests for Asthma-Related Traits 7

Genetic tests related to Asthma-Related Traits 7:

# Genetic test Affiliating Genes
1 Asthma-Related Traits, Susceptibility to, 7 29 CHI3L1

Anatomical Context for Asthma-Related Traits 7

Publications for Asthma-Related Traits 7

Articles related to Asthma-Related Traits 7:

# Title Authors PMID Year
1
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. 6 57
18403759 2008
2
A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. 57
16391567 2006
3
Genetics of asthma and related phenotypes. 57
12065182 2002
4
A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. 57
11326283 2001

Variations for Asthma-Related Traits 7

ClinVar genetic disease variations for Asthma-Related Traits 7:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 CHI3L1 NM_001276.2(CHI3L1):c.-131C>G SNV risk factor 8112 rs4950928 GRCh37: 1:203155882-203155882
GRCh38: 1:203186754-203186754

Expression for Asthma-Related Traits 7

Search GEO for disease gene expression data for Asthma-Related Traits 7.

Pathways for Asthma-Related Traits 7

GO Terms for Asthma-Related Traits 7

Sources for Asthma-Related Traits 7

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....