MCID: AST001
MIFTS: 19

Astrakhan Spotted Fever

Categories: Infectious diseases

Aliases & Classifications for Astrakhan Spotted Fever

MalaCards integrated aliases for Astrakhan Spotted Fever:

Name: Astrakhan Spotted Fever 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050041

Summaries for Astrakhan Spotted Fever

Disease Ontology : 12 A spotted fever that has material basis in Rickettsia conorii subsp caspia, which is transmitted by ticks (Rhipicephalus pumilio and Rhipicephalus sanguineus). The infection has symptom fever, has symptom eschar (usually single), has symptom regional adenopathy, has symptom maculopapular rash on extremities.

MalaCards based summary : Astrakhan Spotted Fever is related to scrub typhus and spotted fever, and has symptoms including fever, eschar and regional adenopathy. An important gene associated with Astrakhan Spotted Fever is PUS10 (Pseudouridine Synthase 10). Affiliated tissues include lung and skin.

Related Diseases for Astrakhan Spotted Fever

Diseases related to Astrakhan Spotted Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 scrub typhus 30.1 F3 CD40LG
2 spotted fever 30.1 CD40LG CCL5
3 exanthem 30.1 F3 CD40LG
4 epidemic typhus 29.7 CD40LG CCL5
5 siberian tick typhus 10.3 PUS10 CMPK1
6 heparin-induced thrombocytopenia 10.0 F3 CD40LG
7 fournier gangrene 10.0 F3 CD40LG
8 catastrophic antiphospholipid syndrome 10.0 F3 CD40LG
9 antiphospholipid syndrome 10.0 F3 CD40LG
10 intracranial sinus thrombosis 10.0 F3 CD40LG
11 volkmann contracture 10.0 F3 CD40LG
12 splenic sequestration 10.0 F3 CD40LG
13 splenic infarction 10.0 F3 CD40LG
14 rocky mountain spotted fever 10.0 F3 CD40LG
15 hantavirus pulmonary syndrome 10.0 F3 CD40LG
16 ebola hemorrhagic fever 10.0 F3 CD40LG
17 hantavirus hemorrhagic fever with renal syndrome 10.0 F3 CD40LG
18 papilledema 10.0 F3 CD40LG
19 anuria 10.0 F3 CD40LG
20 primary thrombocytopenia 10.0 F3 CD40LG
21 thrombophlebitis 10.0 F3 CD40LG
22 autoimmune disease of blood 10.0 F3 CD40LG
23 aspiration pneumonia 10.0 F3 CD40LG
24 pericardium disease 10.0 F3 CD40LG
25 pulmonary artery disease 10.0 F3 CD40LG
26 splenic disease 9.9 F3 CD40LG
27 mycoplasma pneumoniae pneumonia 9.9 F3 CD40LG
28 endocardium disease 9.9 F3 CD40LG
29 hepatic vascular disease 9.9 F3 CD40LG
30 blood protein disease 9.9 F3 CD40LG
31 pericardial effusion 9.9 F3 CD40LG
32 retinal vein occlusion 9.9 F3 CD40LG
33 vein disease 9.9 F3 CD40LG
34 thrombotic thrombocytopenic purpura 9.9 F3 CD40LG
35 purpura 9.9 F3 CD40LG
36 dengue hemorrhagic fever 9.9 F3 CD40LG
37 bilirubin metabolic disorder 9.8 F3 CD40LG
38 hemorrhagic disease 9.8 F3 CD40LG
39 blood coagulation disease 9.8 F3 CD40LG
40 hemolytic-uremic syndrome 9.8 F3 CD40LG
41 portal hypertension 9.8 F3 CD40LG
42 toxic shock syndrome 9.8 F3 CD40LG
43 maxillary sinusitis 9.8 CD40LG CCL5
44 idiopathic neutropenia 9.7 CD40LG CCL5
45 african tick-bite fever 9.7 CD40LG CCL5
46 viral meningitis 9.7 CD40LG CCL5
47 bullous skin disease 9.7 CD40LG CCL5
48 pulmonary embolism 9.7 F3 CD40LG
49 conjunctival disease 9.7 CD40LG CCL5
50 viral encephalitis 9.7 CD40LG CCL5

Graphical network of the top 20 diseases related to Astrakhan Spotted Fever:



Diseases related to Astrakhan Spotted Fever

Symptoms & Phenotypes for Astrakhan Spotted Fever

Symptoms:

12
  • fever
  • eschar
  • regional adenopathy
  • maculopapular rash on extremities

Drugs & Therapeutics for Astrakhan Spotted Fever

Search Clinical Trials , NIH Clinical Center for Astrakhan Spotted Fever

Genetic Tests for Astrakhan Spotted Fever

Anatomical Context for Astrakhan Spotted Fever

MalaCards organs/tissues related to Astrakhan Spotted Fever:

40
Lung, Skin

Publications for Astrakhan Spotted Fever

Articles related to Astrakhan Spotted Fever:

# Title Authors PMID Year
1
[Retrospective serological diagnostics of spotted fever group rickettsioses in high risk areas of Rickettsia conorii subsp. Caspia infection.] 61
31200408 2019
2
[Information technologies in epidemiological control of natural-focal infectious diseases]. 61
23805655 2013
3
[Scientific collaboration of Russia and France in the study of ricketsioses]. 61
18756786 2008
4
Rickettsial diseases in Russia. 61
17114680 2006
5
Problems and perspectives of molecular epidemiology of infectious diseases. 61
12860718 2003
6
[Bacterial zoonoses with natural focality: current trends in epidemic manifestation]. 61
12506638 2002
7
Cytokins in the pathogenesis of astrakhan spotted Fever and North Asian scrub typhus: problems of immunocorrection. 61
12459842 2002
8
[New and emerging rickettsial and bartonella infections]. 61
11837209 2001
9
Studies of a "new" rickettsiosis "Astrakhan" spotted fever. 61
1884783 1991

Variations for Astrakhan Spotted Fever

Expression for Astrakhan Spotted Fever

Search GEO for disease gene expression data for Astrakhan Spotted Fever.

Pathways for Astrakhan Spotted Fever

GO Terms for Astrakhan Spotted Fever

Biological processes related to Astrakhan Spotted Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of T cell proliferation GO:0042102 8.96 CD40LG CCL5
2 leukocyte cell-cell adhesion GO:0007159 8.62 CD40LG CCL5

Sources for Astrakhan Spotted Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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