MCID: ASY001
MIFTS: 18

Asymptomatic Dengue

Categories: Infectious diseases

Aliases & Classifications for Asymptomatic Dengue

MalaCards integrated aliases for Asymptomatic Dengue:

Name: Asymptomatic Dengue 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050143

Summaries for Asymptomatic Dengue

Disease Ontology : 12 A dengue disease that results in infection, has material basis in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted by Aedes mosquito bite. The infection has no manifestations of symptoms.

MalaCards based summary : Asymptomatic Dengue is related to dengue virus and viral infectious disease. An important gene associated with Asymptomatic Dengue is FCGR2A (Fc Fragment Of IgG Receptor IIa), and among its related pathways/superpathways are Matrix Metalloproteinases and Cell adhesion_ECM remodeling. The drugs Antibodies and Vaccines have been mentioned in the context of this disorder. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Asymptomatic Dengue

Diseases related to Asymptomatic Dengue via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dengue virus 10.1
2 viral infectious disease 9.9
3 guillain-barre syndrome 9.8
4 lupus erythematosus 9.7 C1S FCGR2A

Symptoms & Phenotypes for Asymptomatic Dengue

GenomeRNAi Phenotypes related to Asymptomatic Dengue according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.32 MMP15
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.32 MMP15
3 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.32 FCGR2A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.32 FCGR2A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.32 FCGR2A MMP15
6 Increased shRNA abundance (Z-score > 2) GR00366-A-172 9.32 MMP15
7 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.32 MMP15
8 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.32 MMP15
9 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.32 FCGR2A

Drugs & Therapeutics for Asymptomatic Dengue

Drugs for Asymptomatic Dengue (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies Not Applicable
2 Vaccines Not Applicable
3 Immunoglobulins Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children Completed NCT01391819 Not Applicable

Search NIH Clinical Center for Asymptomatic Dengue

Genetic Tests for Asymptomatic Dengue

Anatomical Context for Asymptomatic Dengue

Publications for Asymptomatic Dengue

Articles related to Asymptomatic Dengue:

# Title Authors Year
1
Low frequency of asymptomatic dengue virus-infected donors in blood donor centers during the largest dengue outbreak in Taiwan. ( 30296301 )
2018
2
Seroprevalence of Asymptomatic Dengue Virus Infection and Its Antibodies Among Healthy/Eligible Saudi Blood Donors: Findings From Holy Makkah City. ( 28469422 )
2017
3
Tetravalent Dengue Vaccine Reduces Symptomatic and Asymptomatic Dengue Virus Infections in Healthy Children and Adolescents Aged 2-16 Years in Asia and Latin America. ( 27418050 )
2016
4
Seroepidemiology of Asymptomatic Dengue Virus Infection in Jeddah, Saudi Arabia. ( 26917954 )
2016
5
Asymptomatic dengue infection may trigger Guillain-Barré syndrome. ( 27717230 )
2016
6
Asymptomatic dengue infection in a Cuban population confirms the protective role of the RR variant of the FcgammaRIIa polymorphism. ( 20519616 )
2010

Variations for Asymptomatic Dengue

Expression for Asymptomatic Dengue

Search GEO for disease gene expression data for Asymptomatic Dengue.

Pathways for Asymptomatic Dengue

Pathways related to Asymptomatic Dengue according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.25 MMP10 MMP15
2 10.94 MMP10 MMP15
3
Show member pathways
10.9 C1S FCGR2A MMP10
4 10.7 C1S FCGR2A

GO Terms for Asymptomatic Dengue

Biological processes related to Asymptomatic Dengue according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.33 C1S MMP10 MMP15
2 extracellular matrix disassembly GO:0022617 8.96 MMP10 MMP15
3 collagen catabolic process GO:0030574 8.62 MMP10 MMP15

Molecular functions related to Asymptomatic Dengue according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metallopeptidase activity GO:0008237 9.16 MMP10 MMP15
2 metalloendopeptidase activity GO:0004222 8.96 MMP10 MMP15
3 peptidase activity GO:0008233 8.8 C1S MMP10 MMP15

Sources for Asymptomatic Dengue

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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