MCID: ATR024
MIFTS: 19

Atrial Fibrillation and Stroke

Aliases & Classifications for Atrial Fibrillation and Stroke

MalaCards integrated aliases for Atrial Fibrillation and Stroke:

Name: Atrial Fibrillation and Stroke 54

Summaries for Atrial Fibrillation and Stroke

NINDS : 54 Atrial fibrillation (AF) describes the rapid, irregular beating of the left atrium (upper chamber) of the heart. These rapid contractions of the heart are weaker than normal contractions, resulting in slow flow of blood in the atrium. The blood pools and becomes sluggish and can result in the formation of blood clots. If a clot leaves the heart and travels to the brain, it can cause a stroke by blocking the flow of blood through cerebral arteries. Some people with AF have no symptoms, but others may experience a fluttering feeling in the area of the chest above the heart, chest pain, lightheadness or fainting, shortness of breath, and fatigue. AF is diagnosed by an electrocardiogram (ECG), a device that records the heart’s electrical activity. Other tests are often performed to rule out contributing causes, such as high blood pressure, an overactive thyroid gland, heart failure, faulty heart valves, lung disease, and stimulant or alcohol abuse. Some people will have no identifiable cause for their AF.

MalaCards based summary : Atrial Fibrillation and Stroke is related to atrial fibrillation and atrial heart septal defect. An important gene associated with Atrial Fibrillation and Stroke is NPPA (Natriuretic Peptide A). The drug Anticoagulants has been mentioned in the context of this disorder. Affiliated tissues include heart, thyroid and lung.

Related Diseases for Atrial Fibrillation and Stroke

Diseases related to Atrial Fibrillation and Stroke via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 atrial fibrillation 10.7
2 atrial heart septal defect 10.1
3 apnea, obstructive sleep 9.8
4 arteries, anomalies of 9.8
5 aging 9.8
6 myocardial infarction 9.8
7 acute myocardial infarction 9.8
8 inflammatory bowel disease 9.8
9 peripheral artery disease 9.8
10 sleep apnea 9.8
11 sick sinus syndrome 9.8
12 sleep disorder 9.8
13 psoriasis 9.8
14 depression 9.8

Graphical network of the top 20 diseases related to Atrial Fibrillation and Stroke:



Diseases related to Atrial Fibrillation and Stroke

Symptoms & Phenotypes for Atrial Fibrillation and Stroke

Drugs & Therapeutics for Atrial Fibrillation and Stroke

Drugs for Atrial Fibrillation and Stroke (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anticoagulants Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial Completed NCT00256152 Phase 4
2 SILENT - Subclinical AtrIal FibrilLation and StrokE PreveNtion Trial Not yet recruiting NCT02004509 Phase 4 anticoagulant by physician criteria
3 Atrial Fibrillation in Cryptogenic Stroke and TIA Recruiting NCT02937077
4 Ischemia Care Biomarkers of Acute Stroke Etiology (BASE) Recruiting NCT02014896
5 Characterization and Prediction of Atrial Fibrillation-caused Adverse Events After Hospital Discharge for Cardiac Surgery Active, not recruiting NCT03466125

Search NIH Clinical Center for Atrial Fibrillation and Stroke

Genetic Tests for Atrial Fibrillation and Stroke

Anatomical Context for Atrial Fibrillation and Stroke

MalaCards organs/tissues related to Atrial Fibrillation and Stroke:

41
Heart, Thyroid, Lung, Brain, Testes, Kidney

Publications for Atrial Fibrillation and Stroke

Articles related to Atrial Fibrillation and Stroke:

(show top 50) (show all 62)
# Title Authors Year
1
Atrial fibrillation and stroke risk factors induce decline in creatinine clearance: Is there a specific "fibrillatory kidney disease"? ( 29306477 )
2018
2
Atrial fibrillation and stroke prevention: where we are and where we should be. ( 29853572 )
2018
3
Incident Atrial Fibrillation and Stroke in Patients With Atrial Flutter. ( 29729880 )
2018
4
Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter-A Population-Based Study. ( 29801742 )
2018
5
Atrial fibrillation and stroke: The more we learn, the less we understand. ( 29910049 )
2018
6
Subclinical device-detected atrial fibrillation and stroke risk: a systematic review and meta-analysis. ( 29340587 )
2018
7
Stroke type and severity in patients with subclinical atrial fibrillation: An analysis from the Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT). ( 29764671 )
2018
8
Pro-atrial natriuretic peptide and prediction of atrial fibrillation and stroke: The MalmAP Preventive Project. ( 28195503 )
2017
9
Cancer, atrial fibrillation, and stroke. ( 28528288 )
2017
10
Long-Term Risk of Atrial Fibrillation and Stroke in Patients With Atrial Septal Defect Diagnosed in Childhood. ( 27939228 )
2017
11
Impact of pro-atrial natriuretic peptide in atrial fibrillation and stroke. ( 28452559 )
2017
12
Epidemiology and Management of Atrial Fibrillation and Stroke: Review of Data from Four European Countries. ( 28634569 )
2017
13
Atrial fibrillation and stroke as initial manifestations of painless type A aortic dissection. ( 28803639 )
2017
14
Some light in the shadows of atrial fibrillation and stroke: To look or not to look. ( 28904089 )
2017
15
Global longitudinal strain predicts incident atrial fibrillation and stroke occurrence after acute myocardial infarction. ( 27858918 )
2016
16
Atrial Fibrillation and Stroke: Making Sense of Recent Observations on Anticoagulation. ( 27150180 )
2016
17
New perspectives on atrial fibrillation and stroke. ( 27559092 )
2016
18
The Presence of a Large Chiari Network in a Patient with Atrial Fibrillation and Stroke. ( 27547469 )
2016
19
The Epidemiology of Atrial Fibrillation and Stroke. ( 27150174 )
2016
20
The Influence of Left Atrial Enlargement on the Relationship between Atrial Fibrillation and Stroke. ( 27012217 )
2016
21
Atrial fibrillation and stroke: risk factors, anticoagulation, and left atrial appendage occluders. ( 27558318 )
2016
22
Atrial fibrillation and stroke: unrecognised and undertreated. ( 27560257 )
2016
23
Specific risk of atrial fibrillation and stroke in oncology patients. ( 27694543 )
2016
24
Postoperative Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery Predicts Long-Term Atrial Fibrillation and Stroke. ( 28457078 )
2016
25
Metabolic syndrome, atrial fibrillation, and stroke: Tackling an emerging epidemic. ( 26142297 )
2015
26
Phosphodiesterase4D (PDE4D)--A risk factor for atrial fibrillation and stroke? ( 26671126 )
2015
27
Recent advances in atrial fibrillation and stroke. ( 25875354 )
2015
28
HRS/NSA 2014 survey of atrial fibrillation and stroke: Gaps in knowledge and perspective, opportunities for improvement. ( 25981149 )
2015
29
Association of Atrial Fibrillation and Stroke: Analysis of Maccabi Health Services Cardiovascular Database. ( 26394490 )
2015
30
Early detection of occult atrial fibrillation and stroke prevention. ( 25935765 )
2015
31
Outcome of men and women after atrial fibrillation and stroke. ( 25649996 )
2015
32
Atrial fibrillation and stroke after atrial septal defect closure. Is earlier closure warranted? ( 25711960 )
2015
33
Complex interventional treatment in a patient with atrial fibrillation and stroke caused by large carotid artery thrombus: a case report. ( 25902793 )
2015
34
Atrial Fibrillation and Stroke: It's About Point of View. ( 25935313 )
2015
35
Subclinical atrial fibrillation and stroke: insights from continuous monitoring by implanted cardiac electronic devices. ( 26842114 )
2015
36
ATRIAL FIBRILLATION AND STROKE PREVENTION PRACTICES IN PATIENTS WITH CANDIDACY FOR ANTICOAGULATION THERAPY. ( 26721036 )
2015
37
HRS/NSA 2014 Survey of Atrial Fibrillation and Stroke: Gaps in Knowledge and Perspective, Opportunities for Improvement. ( 26255580 )
2015
38
The association of the QT interval with atrial fibrillation and stroke: the Multi-Ethnic Study of Atherosclerosis. ( 25752461 )
2015
39
Association between depression and risk of atrial fibrillation and stroke in patients with psoriasis: a Danish nationwide cohort study. ( 25781210 )
2015
40
Atrial fibrillation and stroke in adult patients with atrial septal defect and the long-term effect of closure. ( 25691512 )
2015
41
Atrial fibrillation and stroke: epidemiology. ( 24655742 )
2014
42
Atrial fibrillation and stroke prevention in aging patients: what's good can be even better. ( 24895453 )
2014
43
Atrial fibrillation and stroke - Coexistence and attitude to preventive therapy on the basis of Szczecin and Szczecin region patients. ( 25482252 )
2014
44
Prevalence of risk factors for atrial fibrillation and stroke among 1210 patients with sleep disordered breathing. ( 24726170 )
2014
45
Asymptomatic atrial fibrillation and stroke risk. ( 24864620 )
2014
46
Risk of new-onset atrial fibrillation and stroke after radiofrequency ablation of isolated, typical atrial flutter. ( 24998999 )
2014
47
Postoperative atrial fibrillation and stroke--is it time to act? ( 24552515 )
2014
48
Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke. ( 25123217 )
2014
49
Peripheral arterial disease and risk of atrial fibrillation and stroke: the multi-ethnic study of atherosclerosis. ( 25404190 )
2014
50
Atrial fibrillation and stroke prevention: brief observations on the last decade. ( 24650307 )
2014

Variations for Atrial Fibrillation and Stroke

Expression for Atrial Fibrillation and Stroke

Search GEO for disease gene expression data for Atrial Fibrillation and Stroke.

Pathways for Atrial Fibrillation and Stroke

GO Terms for Atrial Fibrillation and Stroke

Biological processes related to Atrial Fibrillation and Stroke according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 8.62 NPPA PDE4D

Sources for Atrial Fibrillation and Stroke

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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