MCID: ATR026
MIFTS: 19

Atrial Fibrillation, Familial, 1

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases

Aliases & Classifications for Atrial Fibrillation, Familial, 1

MalaCards integrated aliases for Atrial Fibrillation, Familial, 1:

Name: Atrial Fibrillation, Familial, 1 57 29 13 73
Atrial Fibrillation, Autosomal Dominant 57
Atfb1 57

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant

Miscellaneous:
average age at diagnosis 17.8 years (range 2-35 years)
genetic heterogeneity (see, e.g., atfb3, )


HPO:

32
atrial fibrillation, familial, 1:
Inheritance autosomal dominant inheritance heterogeneous


Classifications:



External Ids:

OMIM 57 608583
MedGen 42 C1843687
SNOMED-CT via HPO 69 263681008 49436004
UMLS 73 C1843687

Summaries for Atrial Fibrillation, Familial, 1

OMIM : 57 Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997). (608583)

MalaCards based summary : Atrial Fibrillation, Familial, 1, also known as atrial fibrillation, autosomal dominant, is related to familial atrial fibrillation and atrial fibrillation. An important gene associated with Atrial Fibrillation, Familial, 1 is ATFB1 (Atrial Fibrillation, Familial 1). Affiliated tissues include heart, and related phenotypes are thromboembolic stroke and atrial fibrillation

Related Diseases for Atrial Fibrillation, Familial, 1

Symptoms & Phenotypes for Atrial Fibrillation, Familial, 1

Symptoms via clinical synopsis from OMIM:

57
Cardiovascular Heart:
atrial fibrillation, isolated
rapid heart beat
irregular heart beat
thromboembolic stroke may occur


Clinical features from OMIM:

608583

Human phenotypes related to Atrial Fibrillation, Familial, 1:

32
# Description HPO Frequency HPO Source Accession
1 thromboembolic stroke 32 frequent (33%) HP:0001727
2 atrial fibrillation 32 HP:0005110

Drugs & Therapeutics for Atrial Fibrillation, Familial, 1

Search Clinical Trials , NIH Clinical Center for Atrial Fibrillation, Familial, 1

Genetic Tests for Atrial Fibrillation, Familial, 1

Genetic tests related to Atrial Fibrillation, Familial, 1:

# Genetic test Affiliating Genes
1 Atrial Fibrillation, Familial, 1 29

Anatomical Context for Atrial Fibrillation, Familial, 1

MalaCards organs/tissues related to Atrial Fibrillation, Familial, 1:

41
Heart

Publications for Atrial Fibrillation, Familial, 1

Variations for Atrial Fibrillation, Familial, 1

Expression for Atrial Fibrillation, Familial, 1

Search GEO for disease gene expression data for Atrial Fibrillation, Familial, 1.

Pathways for Atrial Fibrillation, Familial, 1

GO Terms for Atrial Fibrillation, Familial, 1

Sources for Atrial Fibrillation, Familial, 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....