Atrial Fibrillation, Familial, 14 (ATFB14)

External Ids:

OMIM 56 615378 OMIM Phenotypic Series 56 PS608583 MeSH 43 D001281

MedGen 41 C3809312 CN179766 SNOMED-CT via HPO 68 164931005 164947007 24184005 263681008 282825002 38341003 76388001 more UMLS 71 C3809312

OMIM : ⁵⁶ Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997). For a discussion of genetic heterogeneity of familial atrial fibrillation, see ATFB1 (608583). (615378)

MalaCards based summary : Atrial Fibrillation, Familial, 14, is also known as atfb14. An important gene associated with Atrial Fibrillation, Familial, 14 is SCN2B (Sodium Voltage-Gated Channel Beta Subunit 2). Affiliated tissues include heart, and related phenotypes are hypertension and paroxysmal atrial fibrillation

UniProtKB/Swiss-Prot : ⁷³ Atrial fibrillation, familial, 14: A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure.

Clinical features from OMIM:

615378

Search Clinical Trials , NIH Clinical Center for Atrial Fibrillation, Familial, 14

Search GEO for disease gene expression data for Atrial Fibrillation, Familial, 14.