ATFB5
MCID: ATR027
MIFTS: 15

Atrial Fibrillation, Familial, 5 (ATFB5)

Categories: Blood diseases, Cardiovascular diseases, Genetic diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Atrial Fibrillation, Familial, 5

MalaCards integrated aliases for Atrial Fibrillation, Familial, 5:

Name: Atrial Fibrillation, Familial, 5 56 13 71
Atfb5 56

Characteristics:

HPO:

31
atrial fibrillation, familial, 5:
Inheritance polygenic inheritance


Classifications:



External Ids:

OMIM 56 611494
OMIM Phenotypic Series 56 PS608583
MedGen 41 C1969099
SNOMED-CT via HPO 68 49436004
UMLS 71 C1969099

Summaries for Atrial Fibrillation, Familial, 5

OMIM : 56 Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997). For a discussion of genetic heterogeneity of atrial fibrillation, see 608583. (611494)

MalaCards based summary : Atrial Fibrillation, Familial, 5, also known as atfb5, is related to atrial fibrillation and familial atrial fibrillation. An important gene associated with Atrial Fibrillation, Familial, 5 is ATFB5 (Atrial Fibrillation, Familial, 5). Related phenotype is atrial fibrillation.

Related Diseases for Atrial Fibrillation, Familial, 5

Symptoms & Phenotypes for Atrial Fibrillation, Familial, 5

Human phenotypes related to Atrial Fibrillation, Familial, 5:

31
# Description HPO Frequency HPO Source Accession
1 atrial fibrillation 31 HP:0005110

Clinical features from OMIM:

611494

Drugs & Therapeutics for Atrial Fibrillation, Familial, 5

Search Clinical Trials , NIH Clinical Center for Atrial Fibrillation, Familial, 5

Genetic Tests for Atrial Fibrillation, Familial, 5

Anatomical Context for Atrial Fibrillation, Familial, 5

Publications for Atrial Fibrillation, Familial, 5

Articles related to Atrial Fibrillation, Familial, 5:

# Title Authors PMID Year
1
A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a. 56
27866707 2016
2
Common variants in KCNN3 are associated with lone atrial fibrillation. 56
20173747 2010
3
Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population. 56
19707791 2009
4
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. 56
19597491 2009
5
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. 56
19597492 2009
6
Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. 56
18991354 2008
7
Variants conferring risk of atrial fibrillation on chromosome 4q25. 56
17603472 2007
8
Identification of a genetic locus for familial atrial fibrillation. 56
9070470 1997

Variations for Atrial Fibrillation, Familial, 5

Expression for Atrial Fibrillation, Familial, 5

Search GEO for disease gene expression data for Atrial Fibrillation, Familial, 5.

Pathways for Atrial Fibrillation, Familial, 5

GO Terms for Atrial Fibrillation, Familial, 5

Sources for Atrial Fibrillation, Familial, 5

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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