MCID: ATR055
MIFTS: 22

Atrial Septal Aneurysm

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Atrial Septal Aneurysm

MalaCards integrated aliases for Atrial Septal Aneurysm:

Name: Atrial Septal Aneurysm 58 6 70

Classifications:

Orphanet: 58  
Rare cardiac malformations
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 33 Q21.1
UMLS via Orphanet 71 C0521533
Orphanet 58 ORPHA99107
UMLS 70 C0521533

Summaries for Atrial Septal Aneurysm

MalaCards based summary : Atrial Septal Aneurysm is related to patent foramen ovale and atrial heart septal defect. An important gene associated with Atrial Septal Aneurysm is SERPINA1 (Serpin Family A Member 1). The drug Tea has been mentioned in the context of this disorder. Affiliated tissues include heart, cerebellum and retina.

Related Diseases for Atrial Septal Aneurysm

Diseases related to Atrial Septal Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 patent foramen ovale 11.4
2 atrial heart septal defect 11.3
3 aneurysm 11.0
4 heart septal defect 10.8
5 orthostatic intolerance 10.7
6 intracranial embolism 10.5
7 transient cerebral ischemia 10.5
8 interatrial communication 10.4
9 progressive familial heart block, type ia 10.3
10 migraine with or without aura 1 10.3
11 mitral valve stenosis 10.3
12 stroke, ischemic 10.3
13 progressive familial heart block, type ib 10.3
14 migraine with aura 10.3
15 right bundle branch block 10.3
16 pulmonary embolism 10.3
17 atrial fibrillation 10.2
18 mitral valve insufficiency 10.2
19 ventricular septal defect 10.2
20 thrombophilia 10.2
21 atrial standstill 1 10.1
22 pulmonary hypertension 10.1
23 hypoplastic right heart syndrome 10.1
24 dilated cardiomyopathy 10.1
25 ischemia 10.1
26 restrictive cardiomyopathy 10.1
27 mitral valve disease 10.1
28 cerebrovascular disease 10.1
29 cor triatriatum 10.1
30 headache 10.1
31 aortic valve disease 1 10.0
32 cardiac arrhythmia 10.0
33 cardiac conduction defect 10.0
34 hypercholesterolemia, familial, 1 10.0
35 juvenile polyposis syndrome 10.0
36 supravalvular aortic stenosis 10.0
37 thrombophilia due to activated protein c resistance 10.0
38 wolff-parkinson-white syndrome 10.0
39 cutis marmorata telangiectatica congenita 10.0
40 pseudoxanthoma elasticum 10.0
41 pulmonary arteriovenous fistulas 10.0
42 tricuspid atresia 10.0
43 patent ductus arteriosus 1 10.0
44 cyanosis, transient neonatal 10.0
45 atrial septal defect 3 10.0
46 atrioventricular block 10.0
47 aphasia 10.0
48 colitis 10.0
49 ischemic colitis 10.0
50 polycystic kidney disease 10.0

Graphical network of the top 20 diseases related to Atrial Septal Aneurysm:



Diseases related to Atrial Septal Aneurysm

Symptoms & Phenotypes for Atrial Septal Aneurysm

Drugs & Therapeutics for Atrial Septal Aneurysm

Drugs for Atrial Septal Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Tea

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Transcatheter Exclusion of Atrial Septal Aneurysm Via Transseptal Perforation: First-in-human Use Study Recruiting NCT04561882

Search NIH Clinical Center for Atrial Septal Aneurysm

Genetic Tests for Atrial Septal Aneurysm

Anatomical Context for Atrial Septal Aneurysm

MalaCards organs/tissues related to Atrial Septal Aneurysm:

40
Heart, Cerebellum, Retina, Neutrophil

Publications for Atrial Septal Aneurysm

Articles related to Atrial Septal Aneurysm:

(show top 50) (show all 740)
# Title Authors PMID Year
1
Closure or medical therapy of patent foramen ovale in cryptogenic stroke: prospective case series. 61
33789756 2021
2
Ischemic colitis and atrial septal aneurysm as a potential cause of systemic thromboembolism. 61
33768927 2021
3
Individualized Experience With Percutaneous Transcatheter Closure of Multiple Atrial Septal Defects: A Single-Center Study. 61
33659280 2021
4
Transcatheter closure of patent foramen ovale: Current evidence and future perspectives. 61
33144025 2021
5
Transcranial Doppler as a Screening Tool for High-Risk Patent Foramen Ovale in Cryptogenic Stroke. 61
32896963 2021
6
Patent foramen ovale closure in non-lacunar cryptogenic ischemic stroke: where are we now? 61
33613660 2021
7
Device closure for patent foramen ovale in patients with cryptogenic stroke: which patients should get it? 61
33664639 2020
8
Predictive value of free fatty acid levels in embolic stroke of undetermined source: A retrospective observational study. 61
33019438 2020
9
A giant atrial septal aneurysm causing tricuspid valvular obstruction. 61
31930731 2020
10
Predictors of Residual Right-to-Left Shunt After Percutaneous Suture-Mediated Patent Fossa Ovalis Closure. 61
32972572 2020
11
Transseptal occluder migration after transcatheter atrial septal aneurysm and double secondary septal defect correction: A case report. 61
32566068 2020
12
Importance of Persistent Right-to-Left Shunt After Patent Foramen Ovale Closure in Cryptogenic Stroke Patients. 61
33472221 2020
13
Patent foramen ovale closure in children without cardiopathy: Child-PFO study. 61
32680737 2020
14
Rare Association of Patent Foramen Ovale and Atrial Septal Aneurysm Leading to Branch Retinal Artery Occlusion in a Young Healthy Man. 61
32775076 2020
15
Atrial Septal Aneurysm may Cause In-Hospital Recurrence of Cryptogenic Stroke. 61
32684557 2020
16
Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence: A Prospective Cohort Study. 61
32422058 2020
17
Association between atrial septal aneurysm and arrhythmias. 61
31544553 2020
18
A gigantic atrial septal aneurysm. 61
32617513 2020
19
Cardiovascular MRI: A valuable tool to detect cardiac source of emboli in cryptogenic ischemic strokes. 61
32304360 2020
20
Atrial Septal Aneurysm, Shunt Size, and Recurrent Stroke Risk in Patients With Patent Foramen Ovale. 61
32381162 2020
21
Correlations between serum homocysteine levels and RoPE score in patients with patent foramen ovale. 61
31676957 2020
22
Patent foramen ovale. 61
32299831 2020
23
Acute cerebral infarction with acute myocardial infarction due to patent foramen ovale: A case report. 61
32384468 2020
24
[Isolated atrial septal aneurysm: Exceptional cause of digital ischemia - a case report]. 61
32222284 2020
25
Atrial septal aneurysm in pregnancy: echocardiography and obstetric outcomes. 61
32134736 2020
26
[Patent foramen ovale with a license to kill]. 61
30859250 2020
27
Patent foramen ovale and stroke: current evidence and treatment options. 61
31789709 2020
28
Simultaneous Multifocal Paradoxical Embolism in an Elderly Patient with Patent Foramen Ovale: A Case Report. 61
32206456 2020
29
Morphometric Features of Patent Foramen Ovale as a Risk Factor of Cerebrovascular Accidents: A Systematic Review and Meta-Analysis. 61
32097931 2020
30
Study of transesophageal echocardiography in young patients (<40 years) with acute arterial ischemic stroke: A pilot study. 61
32020968 2020
31
Reprint of : Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology. 61
31787326 2020
32
Left Atrial Function in Young Patients With Cryptogenic Stroke and Patent Foramen Ovale: A Left Atrial Longitudinal Strain Study. 61
33250839 2020
33
Patent Foramen Ovale in Cryptogenic Ischemic Stroke: Direct Cause, Risk Factor, or Incidental Finding? 61
32670184 2020
34
Screening and evaluation of newly diagnosed cardiovascular diseases in first-trimester asymptomatic pregnant women in a tertiary antenatal care center in Turkey. 61
32011322 2020
35
Prior Stroke in PFO Patients Is Associated With Both PFO-Related and -Unrelated Factors. 61
32582015 2020
36
Fetal atrial septal aneurysm: a differential diagnosis of aortic arch retrograde flow. 61
31969409 2020
37
'Windsock' type atrial septal aneurysm in an adult causing paradoxical embolism. 61
32463106 2020
38
Is there any association between rs1303 (Pi*M3) variant of alpha-1 antitrypsin gene and atrial septal aneurysm development? 61
31523846 2019
39
An atrial septal aneurysm with an organized thrombus in an asymptomatic patient: A case report. 61
31770224 2019
40
Stroke in the Young: a Global Update. 61
31768660 2019
41
Patent foramen ovale closure versus medical therapy for cryptogenic stroke: An updated systematic review and meta-analysis. 61
32248916 2019
42
Left atrial enlargement as a maker of significant high-risk patent foramen ovale. 61
31325066 2019
43
Role of 3D transesophageal echocardiography in transcatheter closure of atrial septal aneurysms. 61
31541598 2019
44
Frugal innovation in the cardiac catheter laboratory: Retrograde balloon mitral valvuloplasty using extra back-up guide catheter. 61
31497174 2019
45
Long-Term Outcome After Percutaneous Closure of Patent Foramen Ovale for Cryptogenic Ischemic Events. 61
31368895 2019
46
Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology. 61
31378692 2019
47
Identification of High-Risk Patent Foramen Ovale Associated With Cryptogenic Stroke: Development of a Scoring System. 61
31130417 2019
48
Atrial septal aneurysm with rare comorbid pulmonary arteriovenous malformation as aetiology for cryptogenic stroke. 61
31248896 2019
49
Cutis marmorata in decompression sickness is associated with a patent foramen ovale. 61
31087401 2019
50
Insertable cardiac monitor detection of silent atrial fibrillation in candidates for percutaneous patent foramen ovale closure. 61
30921267 2019

Variations for Atrial Septal Aneurysm

ClinVar genetic disease variations for Atrial Septal Aneurysm:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 RNF213-AS1 , RNF213 NM_001256071.3(RNF213):c.11659A>G (p.Lys3887Glu) SNV Uncertain significance 523426 rs1555673862 GRCh37: 17:78337499-78337499
GRCh38: 17:80363699-80363699

Expression for Atrial Septal Aneurysm

Search GEO for disease gene expression data for Atrial Septal Aneurysm.

Pathways for Atrial Septal Aneurysm

GO Terms for Atrial Septal Aneurysm

Sources for Atrial Septal Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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