MCID: ATR055
MIFTS: 25

Atrial Septal Aneurysm

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Atrial Septal Aneurysm

MalaCards integrated aliases for Atrial Septal Aneurysm:

Name: Atrial Septal Aneurysm 58 71

Classifications:

Orphanet: 58  
Rare cardiac malformations
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 33 Q21.1
UMLS via Orphanet 72 C0521533
Orphanet 58 ORPHA99107
UMLS 71 C0521533

Summaries for Atrial Septal Aneurysm

MalaCards based summary : Atrial Septal Aneurysm is related to aneurysm and patent foramen ovale. The drugs Platelet Aggregation Inhibitors and Anticoagulants have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and brain.

Related Diseases for Atrial Septal Aneurysm

Diseases related to Atrial Septal Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 aneurysm 11.9
2 patent foramen ovale 10.9
3 heart septal defect 10.8
4 atrial heart septal defect 10.7
5 orthostatic intolerance 10.7
6 cerebrovascular disease 10.5
7 stroke, ischemic 10.5
8 transient cerebral ischemia 10.5
9 intracranial embolism 10.5
10 pulmonary embolism 10.5
11 migraine with or without aura 1 10.4
12 interatrial communication 10.4
13 atrial fibrillation 10.4
14 progressive familial heart block, type ia 10.3
15 mitral valve stenosis 10.3
16 progressive familial heart block, type ib 10.3
17 migraine with aura 10.3
18 right bundle branch block 10.3
19 pulmonary hypertension 10.2
20 mitral valve insufficiency 10.2
21 ventricular septal defect 10.2
22 congestive heart failure 10.2
23 supravalvular aortic stenosis 10.1
24 thrombophilia due to thrombin defect 10.1
25 hypoplastic right heart syndrome 10.1
26 endocarditis 10.1
27 dilated cardiomyopathy 10.1
28 thrombophilia 10.1
29 ischemia 10.1
30 restrictive cardiomyopathy 10.1
31 kidney disease 10.1
32 mitral valve disease 10.1
33 cor triatriatum 10.1
34 atrial standstill 1 10.0
35 cardiac arrhythmia 10.0
36 cardiac conduction defect 10.0
37 hypercholesterolemia, familial, 1 10.0
38 juvenile polyposis syndrome 10.0
39 thrombophilia due to activated protein c resistance 10.0
40 wolff-parkinson-white syndrome 10.0
41 cutis marmorata telangiectatica congenita 10.0
42 pseudoxanthoma elasticum 10.0
43 pulmonary arteriovenous fistulas 10.0
44 tricuspid atresia 10.0
45 patent ductus arteriosus 1 10.0
46 cyanosis, transient neonatal 10.0
47 atrial septal defect 3 10.0
48 atrioventricular block 10.0
49 aphasia 10.0
50 polycystic kidney disease 10.0

Graphical network of the top 20 diseases related to Atrial Septal Aneurysm:



Diseases related to Atrial Septal Aneurysm

Symptoms & Phenotypes for Atrial Septal Aneurysm

Drugs & Therapeutics for Atrial Septal Aneurysm

Drugs for Atrial Septal Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Platelet Aggregation Inhibitors Phase 4
2 Anticoagulants Phase 4
3 Coagulants Phase 4
4
Apixaban Approved Phase 3 503612-47-3 10182969
5
Rivaroxaban Approved Phase 3 366789-02-8
6
Dipyridamole Approved Phase 3 58-32-2 3108
7
Dabigatran Investigational Phase 3 211914-51-1
8 HIV Protease Inhibitors Phase 3
9 Fibrinolytic Agents Phase 3
10 Antithrombins Phase 3
11 Anti-Inflammatory Agents Phase 3
12
protease inhibitors Phase 3
13 Analgesics, Non-Narcotic Phase 3
14 Anti-Inflammatory Agents, Non-Steroidal Phase 3
15 Antipyretics Phase 3
16 Serine Proteinase Inhibitors Phase 3
17 Cyclooxygenase Inhibitors Phase 3
18 Aspirin, Dipyridamole Drug Combination Phase 3
19 Antivitamins K Phase 3
20 Antirheumatic Agents Phase 3
21 Analgesics Phase 3
22 Antithrombin III Phase 3
23 Factor Xa Inhibitors Phase 3
24
Serine Investigational, Nutraceutical Phase 3 56-45-1 5951
25
Aspirin Approved, Vet_approved 50-78-2 2244
26
Clopidogrel Approved 120202-66-6, 113665-84-2 60606
27 Neurotransmitter Agents
28 Purinergic P2Y Receptor Antagonists
29 Calamus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Device Closure Versus Medical Therapy for Secondary Prevention in Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale : DEFENSE-PFO Recruiting NCT01550588 Phase 4 Standard medical treatment
2 Interventional Left Atrial Appendage Closure vs. Novel Anticoagulation Agents in High-risk Patients With Atrial Fibrillation (PRAGUE-17 Study) Recruiting NCT02426944 Phase 4 NOAC
3 Closure of Patent Foramen Ovale or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence Completed NCT00562289 Phase 3 aspirin;Antivitamins K or rivaroxaban or dabigatran or apixaban
4 Prospective Clinical Follow-up of Patients Presenting With Cryptogenic Stroke Treated With the Percutaneous Closure of a Patent Foramen Ovale Unknown status NCT01149447
5 Secondary Stroke Prevention In Patients With Patent Foramen Ovale: International PFO Consortium Recruiting NCT00859885 Antithrombotic treatment
6 A Pilot Randomized Controlled Trial of Maternal Oxygen Therapy for Fetal Left Heart Hypoplasia Recruiting NCT02965638
7 Suture Mediated Septal Defect Closure/Repair Evaluation of the NobleStitch EL System Enrolling by invitation NCT03373929
8 Prospective, Open-label, Multicenter, Non-randomized Investigation on Percutaneous Patent Foramen Ovale (PFO) Closure Using the Occlutech PFO Occluder to Prevent Recurrence of Stroke in Patients With Cryptogenic Stroke and High Risk PFO Not yet recruiting NCT04029233

Search NIH Clinical Center for Atrial Septal Aneurysm

Genetic Tests for Atrial Septal Aneurysm

Anatomical Context for Atrial Septal Aneurysm

MalaCards organs/tissues related to Atrial Septal Aneurysm:

40
Heart, Kidney, Brain, Cerebellum, Retina, Skin, Neutrophil

Publications for Atrial Septal Aneurysm

Articles related to Atrial Septal Aneurysm:

(show top 50) (show all 711)
# Title Authors PMID Year
1
Patent foramen ovale and stroke: current evidence and treatment options. 61
31789709 2020
2
Screening and evaluation of newly diagnosed cardiovascular diseases in first-trimester asymptomatic pregnant women in a tertiary antenatal care center in Turkey. 61
32011322 2020
3
Study of transesophageal echocardiography in young patients (<40 years) with acute arterial ischemic stroke: A pilot study. 61
32020968 2020
4
A giant atrial septal aneurysm causing tricuspid valvular obstruction. 61
31930731 2020
5
Fetal atrial septal aneurysm: a differential diagnosis of aortic arch retrograde flow. 61
31969409 2020
6
An atrial septal aneurysm with an organized thrombus in an asymptomatic patient: A case report. 61
31770224 2019
7
Is there any association between rs1303 (Pi*M3) variant of alpha-1 antitrypsin gene and atrial septal aneurysm development? 61
31523846 2019
8
Reprint of : Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology. 61
31787326 2019
9
Left atrial enlargement as a maker of significant high-risk patent foramen ovale. 61
31325066 2019
10
Stroke in the Young: a Global Update. 61
31768660 2019
11
Correlations between serum homocysteine levels and RoPE score in patients with patent foramen ovale. 61
31676957 2019
12
Role of 3D transesophageal echocardiography in transcatheter closure of atrial septal aneurysms. 61
31541598 2019
13
Frugal innovation in the cardiac catheter laboratory: Retrograde balloon mitral valvuloplasty using extra back-up guide catheter. 61
31497174 2019
14
Association between atrial septal aneurysm and arrhythmias. 61
31544553 2019
15
Transcatheter closure of patent foramen ovale to prevent stroke recurrence in patients with otherwise unexplained ischaemic stroke: Expert consensus of the French Neurovascular Society and the French Society of Cardiology. 61
31378692 2019
16
Long-Term Outcome After Percutaneous Closure of Patent Foramen Ovale for Cryptogenic Ischemic Events. 61
31368895 2019
17
Identification of High-Risk Patent Foramen Ovale Associated With Cryptogenic Stroke: Development of a Scoring System. 61
31130417 2019
18
Cutis marmorata in decompression sickness is associated with a patent foramen ovale. 61
31087401 2019
19
Atrial septal aneurysm with rare comorbid pulmonary arteriovenous malformation as aetiology for cryptogenic stroke. 61
31248896 2019
20
Insertable cardiac monitor detection of silent atrial fibrillation in candidates for percutaneous patent foramen ovale closure. 61
30921267 2019
21
Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated meta-analysis of randomized trials. 61
31110604 2019
22
Cardioembolic Sources in Patients With Small Single Subcortical Infarcts. 61
30817491 2019
23
Updated meta-analysis of closure of patent foramen ovale versus medical therapy after cryptogenic stroke. 61
30905408 2019
24
[Patent foramen ovale with a license to kill]. 61
30859250 2019
25
Echocardiographic Findings in Patients with Atrial Septal Aneurysm: A Prospective Case-Control Study. 61
31061729 2019
26
Management of Patients with Patent Foramen Ovale and Cryptogenic Stroke: An Update. 61
31307049 2019
27
Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials. 61
30783525 2019
28
A Proposed Etiology for Atrial Tachyarrhythmia in Neonates with Atrial Septal Aneurysms. 61
30426160 2019
29
Clinical relevance of atrial septal aneurysm and patent foramen ovale with migraine. 61
30568946 2018
30
Current management aspects in adult congenital heart disease: non-surgical closure of patent foramen ovale. 61
30740321 2018
31
Giant atrial septal aneurysm prolapsing into the right ventricle in an asymptomatic infant. 61
30391977 2018
32
Electrocardiography-gated dual-source computed tomography in the detection of atrial septal aneurysm. 61
30402163 2018
33
Patent foramen ovale closure for patients with cryptogenic stroke: A systematic review and comprehensive meta-analysis of 5 randomized controlled trials and 14 observational studies. 61
29804325 2018
34
Interatrial shunts: technical approaches to percutaneous closure. 61
30246569 2018
35
Updated Meta-analysis on the Closure of Patent Foramen Ovale in Reduction of Stroke Rates: the DEFENSE-PFO Trial Does not Change the Scenario. 61
30517261 2018
36
Is Patent Foramen Ovale Closure More Effective Than Medical Therapy in Preventing Stroke Recurrence in Patients With Cryptogenic Stroke?: A Critically Appraised Topic. 61
30169372 2018
37
[Patent foramen ovale-intervention or pharmaceutical treatment]. 61
29978350 2018
38
Patent foramen ovale and stroke. 61
29680895 2018
39
Is transesophageal echocardiography needed for evaluating tissue-based transient ischemic attack? 61
30028329 2018
40
Multiperforated atrial septal "aneurysm in aneurysm": Percutaneous closure guided by real-time three-dimensional transesophageal echocardiography. 61
29080307 2018
41
Patent foramen ovale closure reduces recurrent stroke risk in cryptogenic stroke: A systematic review and meta-analysis of randomized controlled trials. 61
29983901 2018
42
Closure, Anticoagulation, or Antiplatelet Therapy for Cryptogenic Stroke With Patent Foramen Ovale: Systematic Review of Randomized Trials, Sequential Meta-Analysis, and New Insights From the CLOSE Study. 61
29910193 2018
43
Novel Association of Juvenile Polyposis Syndrome With Atrial Septal Aneurysm and Patent Foramen Ovale: A Case Report. 61
29634562 2018
44
[Clinical analysis of young and middle-aged stroke patients with patent foramen ovale]. 61
29804420 2018
45
Cryptogenic Stroke and High-Risk Patent Foramen Ovale: The DEFENSE-PFO Trial. 61
29544871 2018
46
Patent foramen ovale closure vs. medical therapy for cryptogenic stroke: a meta-analysis of randomized controlled trials. 61
29590333 2018
47
Right Hemothorax Caused by Septal Puncture During Catheter Ablation for Atrial Fibrillation: A Case With Atrial Septal Aneurysm and Pulmonary Emphysema. 61
30067498 2018
48
Ischemic stroke due to embolic heart diseases and associated factors in Benin hospital setting. 61
29571848 2018
49
[Patent foramen ovele, good reasons to close it]. 61
29506302 2018
50
Which Patent Foramen Ovales Need Closure to Prevent Cryptogenic Strokes? 61
29175238 2018

Variations for Atrial Septal Aneurysm

Expression for Atrial Septal Aneurysm

Search GEO for disease gene expression data for Atrial Septal Aneurysm.

Pathways for Atrial Septal Aneurysm

GO Terms for Atrial Septal Aneurysm

Sources for Atrial Septal Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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